Home Other Building Blocks Myristoyl coenzyme A

Myristoyl coenzyme A

CAS No.:
3130-72-1
Catalog Number:
AG00CJ10
Molecular Formula:
C35H62N7O17P3S
Molecular Weight:
977.8898
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
≥ 94%
1 week
United States
$213
- +
25mg
≥ 94%
1 week
United States
$608
- +
100mg
≥ 94%
1 week
United States
$1865
- +
Product Description
Catalog Number:
AG00CJ10
Chemical Name:
Myristoyl coenzyme A
CAS Number:
3130-72-1
Molecular Formula:
C35H62N7O17P3S
Molecular Weight:
977.8898
MDL Number:
MFCD00871327
IUPAC Name:
S-[2-[3-[[(2R)-4-[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-2-hydroxy-3,3-dimethylbutanoyl]amino]propanoylamino]ethyl] tetradecanethioate
InChI:
InChI=1S/C35H62N7O17P3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-26(44)63-19-18-37-25(43)16-17-38-33(47)30(46)35(2,3)21-56-62(53,54)59-61(51,52)55-20-24-29(58-60(48,49)50)28(45)34(57-24)42-23-41-27-31(36)39-22-40-32(27)42/h22-24,28-30,34,45-46H,4-21H2,1-3H3,(H,37,43)(H,38,47)(H,51,52)(H,53,54)(H2,36,39,40)(H2,48,49,50)/t24-,28-,29-,30+,34-/m1/s1
InChI Key:
DUAFKXOFBZQTQE-QSGBVPJFSA-N
SMILES:
CCCCCCCCCCCCCC(=O)SCCNC(=O)CCNC(=O)C(C(COP(=O)(OP(=O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1OP(=O)(O)O)O)n1cnc2c1ncnc2N)O)O)(C)C)O
Properties
Complexity:
1590  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
5  
Defined Bond Stereocenter Count:
0
Exact Mass:
977.314g/mol
Formal Charge:
0
Heavy Atom Count:
63  
Hydrogen Bond Acceptor Count:
22  
Hydrogen Bond Donor Count:
9  
Isotope Atom Count:
0
Molecular Weight:
977.894g/mol
Monoisotopic Mass:
977.314g/mol
Rotatable Bond Count:
32  
Topological Polar Surface Area:
389A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.6  
Literature
Title Journal
A new, robust, and nonradioactive approach for exploring N-myristoylation. Journal of lipid research 20121101
Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids. Nature chemical biology 20111101
Effects of HIV-1 Nef on human N-myristoyltransferase 1. Biochemistry 20110426
Regulation of mammalian desaturases by myristic acid: N-terminal myristoylation and other modulations. Biochimica et biophysica acta 20110101
A new topology of ACBP from Moniliophthora perniciosa. Biochimica et biophysica acta 20100101
Secondary acylation of Vibrio cholerae lipopolysaccharide requires phosphorylation of Kdo. The Journal of biological chemistry 20090918
Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): a homotetrameric hotdog fold thioesterase with selectivity for long-chain fatty acyl-CoAs. The Biochemical journal 20090626
[Evolutionary trace analysis of N-myristoyltransferase family]. Yao xue xue bao = Acta pharmaceutica Sinica 20070201
High resolution crystal structures of unliganded and liganded human liver ACBP reveal a new mode of binding for the acyl-CoA ligand. Proteins 20070101
Identification and characterization of recombinant and native rat myristoyl-CoA: protein N-myristoyltransferases. Molecular and cellular biochemistry 20060601
Increased myocardial N-myristoyltransferase activity in rotenone model of Parkinsonism. International journal of molecular medicine 20050601
Desaturation of myristoyl-CoA to myristoleoyl-CoA by hen liver microsomal delta(9)-desaturase. Journal of agricultural and food chemistry 20040630
Direct desaturation of free myristic acid by hen liver microsomal Delta9-desaturase without prior activation to myristoyl-CoA derivative. Journal of agricultural and food chemistry 20040519
A continuous assay of myristoyl-CoA:protein N-myristoyltransferase for proteomic analysis. Analytical biochemistry 20031101
The acyl-CoA oxidases from the yeast Yarrowia lipolytica: characterization of Aox2p. Archives of biochemistry and biophysics 20021101
Characterization of Type I and Type II myristoyl-CoA:protein N-myristoyltransferases with the Acyl-CoAs found on heterogeneously acylated retinal proteins. Experimental eye research 20020701
A continuous fluorometric assay of myristoyl-coenzyme A:protein N-myristoyltransferase. Analytical biochemistry 20020115
Structures of Saccharomyces cerevisiae N-myristoyltransferase with bound myristoylCoA and peptide provide insights about substrate recognition and catalysis. Biochemistry 20010529
Influence of moderate temperatures on myristoyl-CoA metabolism and acyl-CoA thioesterase activity in the psychrophilic antarctic yeast Rhodotorula aurantiaca. The Journal of biological chemistry 20010420
Crystallographic phasing of myristoyl-CoA-protein N-myristoyltransferase using an iodinated analog of myristoyl-CoA. Acta crystallographica. Section D, Biological crystallography 20010301
Fatty-acyl-CoA thioesters inhibit recruitment of steroid receptor co-activator 1 to alpha and gamma isoforms of peroxisome-proliferator-activated receptors by competing with agonists. The Biochemical journal 20010115
High-affinity binding of fatty acyl-CoAs and peroxisome proliferator-CoA esters to glutathione S-transferases effect on enzymatic activity. European journal of biochemistry 19991101
Properties