Home Other Building Blocks 2-Oxopentanedioic acid

2-Oxopentanedioic acid

CAS No.:
378-50-7
Catalog Number:
AG00CAP8
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
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Quantity
  
Product Description
Catalog Number:
AG00CAP8
Chemical Name:
2-Oxopentanedioic acid
CAS Number:
378-50-7
MDL Number:
MFCD00270557
IUPAC Name:
2-oxopentanedioic acid
InChI:
InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)
InChI Key:
KPGXRSRHYNQIFN-UHFFFAOYSA-N
UNII:
8ID597Z82X
NSC Number:
17391
FEMA Number:
3891
Properties
Complexity:
171  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
146.022g/mol
Formal Charge:
0
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
146.098g/mol
Monoisotopic Mass:
146.022g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
91.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.9  
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The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore. Mitochondrion 20120101
Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry. Brain pathology (Zurich, Switzerland) 20120101
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Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120101
Respiration characteristics of mitochondria in parental and giant transformed cells of the murine Nemeth-Kellner lymphoma. Cell biology international 20120101
Pathological features of new animal models for primary biliary cirrhosis. International journal of hepatology 20120101
Cloning and characterization of chicken fat mass and obesity associated (Fto) gene: fasting affects Fto expression. Domestic animal endocrinology 20120101
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PLOD2 induced under hypoxia is a novel prognostic factor for hepatocellular carcinoma after curative resection. Liver international : official journal of the International Association for the Study of the Liver 20120101
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A novel, simple, and sensitive colorimetric method to determine aromatic amino acid aminotransferase activity using the Salkowski reagent. Folia microbiologica 20120101
Combined inactivation of the Clostridium cellulolyticum lactate and malate dehydrogenase genes substantially increases ethanol yield from cellulose and switchgrass fermentations. Biotechnology for biofuels 20120101
The upregulation of thiamine (vitamin B1) biosynthesis in Arabidopsis thaliana seedlings under salt and osmotic stress conditions is mediated by abscisic acid at the early stages of this stress response. BMC plant biology 20120101
Glutaminase immunoreactivity and enzyme activity is increased in the rat dorsal root ganglion following peripheral inflammation. Pain research and treatment 20120101
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Genomic characterization of the Taylorella genus. PloS one 20120101
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Identification of immunogenic proteins of Waddlia chondrophila. PloS one 20120101
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Proteomic analysis of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis. PloS one 20120101
Comparative metaproteomics and diversity analysis of human intestinal microbiota testifies for its temporal stability and expression of core functions. PloS one 20120101
Caenorhabditis elegans battling starvation stress: low levels of ethanol prolong lifespan in L1 larvae. PloS one 20120101
Novel AlkB dioxygenases--alternative models for in silico and in vivo studies. PloS one 20120101
D-Lactate altered mitochondrial energy production in rat brain and heart but not liver. Nutrition & metabolism 20120101
The diversity of cyanobacterial metabolism: genome analysis of multiple phototrophic microorganisms. BMC genomics 20120101
Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. BMC genomics 20120101
Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction. BMC microbiology 20120101
Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease. Current Alzheimer research 20120101
Protective effect of morin on cardiac mitochondrial function during isoproterenol-induced myocardial infarction in male Wistar rats. Redox report : communications in free radical research 20120101
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Toward a Systemic Understanding of Listeria monocytogenes Metabolism during Infection. Frontiers in microbiology 20120101
Creatine protects against excitoxicity in an in vitro model of neurodegeneration. PloS one 20120101
Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. PloS one 20120101
HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia. PloS one 20120101
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Reconstruction and analysis of a genome-scale metabolic model for Scheffersomyces stipitis. Microbial cell factories 20120101
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The mode of sucrose degradation in potato tubers determines the fate of assimilate utilization. Frontiers in plant science 20120101
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Complete Genome of Ignavibacterium album, a Metabolically Versatile, Flagellated, Facultative Anaerobe from the Phylum Chlorobi. Frontiers in microbiology 20120101
Investigating potential mechanisms of obesity by metabolomics. Journal of biomedicine & biotechnology 20120101
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Enzymatic characterization of isocitrate dehydrogenase from an emerging zoonotic pathogen Streptococcus suis. Biochimie 20110901
Quantitative shotgun proteomics using a uniform ¹⁵N-labeled standard to monitor proteome dynamics in time course experiments reveals new insights into the heat stress response of Chlamydomonas reinhardtii. Molecular & cellular proteomics : MCP 20110901
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Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry. Metabolic engineering 20110901
Mutations to metabolic enzymes in cancer herald a need to unify genetics and biochemistry. Cell cycle (Georgetown, Tex.) 20110901
A switching mechanism in doxorubicin bioactivation can be exploited to control doxorubicin toxicity. PLoS computational biology 20110901
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Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature 20110818
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The organellar genome and metabolic potential of the hydrogen-producing mitochondrion of Nyctotherus ovalis. Molecular biology and evolution 20110801
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Computational analysis of storage synthesis in developing Brassica napus L. (oilseed rape) embryos: flux variability analysis in relation to ¹³C metabolic flux analysis. The Plant journal : for cell and molecular biology 20110801
Arginine synthesis from enteral glutamine in healthy adults in the fed state. American journal of physiology. Endocrinology and metabolism 20110801
Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles. Toxicological sciences : an official journal of the Society of Toxicology 20110801
Exercise training induces similar elevations in the activity of oxoglutarate dehydrogenase and peak oxygen uptake in the human quadriceps muscle. Pflugers Archiv : European journal of physiology 20110801
The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase. Rejuvenation research 20110801
Energetic metabolism of axenic promastigotes of Leishmania (Viannia) braziliensis. Experimental parasitology 20110801
Lipoamide dehydrogenase is essential for both bloodstream and procyclic Trypanosoma brucei. Molecular microbiology 20110801
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Heme biosynthesis and its regulation: towards understanding and improvement of heme biosynthesis in filamentous fungi. Applied microbiology and biotechnology 20110801
Renewable energy from Cyanobacteria: energy production optimization by metabolic pathway engineering. Applied microbiology and biotechnology 20110801
The control of mitochondrial succinate-dependent H2O2 production. Journal of bioenergetics and biomembranes 20110801
Simulation of dissolved CO(2) gradients in a scale-down system: a metabolic and transcriptional study of recombinant Escherichia coli. Biotechnology journal 20110801
Succinate receptors in the kidney. Journal of the American Society of Nephrology : JASN 20110801
Crystallization and preliminary crystallographic analysis of a PHD domain of human JARID1B. Acta crystallographica. Section F, Structural biology and crystallization communications 20110801
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Melatonin and succinate reduce rat liver mitochondrial dysfunction in diabetes. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110801
Can metabolic plasticity be a cause for cancer? Warburg-Waddington legacy revisited. Clinical epigenetics 20110801
Identification of ChIP-seq mapped targets of HP1β due to bombesin/GRP receptor activation. Clinical epigenetics 20110801
Toxicity of alpha-ketoglutarate following 14-days repeated oral administration in Wistar rats. Cellular and molecular biology (Noisy-le-Grand, France) 20110727
Multiple targets of nitric oxide in the tricarboxylic acid cycle of Salmonella enterica serovar typhimurium. Cell host & microbe 20110721
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GSH monoethyl ester rescues mitochondrial defects in cystic fibrosis models. Human molecular genetics 20110715
Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells. The international journal of biochemistry & cell biology 20110701
Combining proteomics of root and shoot mitochondria and transcript analysis to define constitutive and variable components in plant mitochondria. Phytochemistry 20110701
Metabolic fate of a high concentration of glutamine and glutamate in rat brain slices: a ¹³C NMR study. Neurochemistry international 20110701
Thiamine responsive megaloblastic anemia in three Indian children. Indian journal of pediatrics 20110701
Acute arginine supplementation fails to improve muscle endurance or affect blood pressure responses to resistance training. Journal of strength and conditioning research 20110701
Proteomic analysis of protective effects of polysaccharides from Salvia miltiorrhiza against immunological liver injury in mice. Phytotherapy research : PTR 20110701
Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis. Hepatology (Baltimore, Md.) 20110701
Characterization of two critical residues in the effector-binding domain of NtcA in the cyanobacterium Anabaena sp. strain PCC 7120. Current microbiology 20110701
Investigation of phosphorylation status of OdhI protein during penicillin- and Tween 40-triggered glutamate overproduction by Corynebacterium glutamicum. Applied microbiology and biotechnology 20110701
Does ear C sink strength contribute to overcoming photosynthetic acclimation of wheat plants exposed to elevated CO2? Journal of experimental botany 20110701
Alterations in urinary metabolites due to unilateral ureteral obstruction in a rodent model. Molecular bioSystems 20110701
Gene profiling and characterization of arginine kinase-1 (MrAK-1) from freshwater giant prawn (Macrobrachium rosenbergii). Fish & shellfish immunology 20110701
Maternal nutrient restriction during late gestation and early postnatal growth in sheep differentially reset the control of energy metabolism in the gastric mucosa. Endocrinology 20110701
Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection. Trends in microbiology 20110701
Pharmacological effect of carvacrol on D: -galactosamine-induced mitochondrial enzymes and DNA damage by single-cell gel electrophoresis. Journal of natural medicines 20110701
Genomic analysis of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles. Extremophiles : life under extreme conditions 20110701
Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress. Epigenetics 20110701
Glioma-derived mutations in isocitrate dehydrogenase 2 beneficial to traditional chemotherapy. Biochemical and biophysical research communications 20110701
Identification of metabolic network models from incomplete high-throughput datasets. Bioinformatics (Oxford, England) 20110701
Detection of tumor glutamate metabolism in vivo using (13)C magnetic resonance spectroscopy and hyperpolarized [1-(13)C]glutamate. Magnetic resonance in medicine 20110701
Suppression of glutamate synthase genes significantly affects carbon and nitrogen metabolism in rice (Oryza sativa L.). Science China. Life sciences 20110701
Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism. PLoS pathogens 20110701
Protective effect of aqueous garlic extract against lead-induced hepatic injury in rats. Indian journal of experimental biology 20110701
In silico evidence for gluconeogenesis from fatty acids in humans. PLoS computational biology 20110701
¹³C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation. PLoS pathogens 20110701
Flux balance analysis for ethylene formation in genetically engineered Saccharomyces cerevisiae. IET systems biology 20110701
Lysine α-ketoglutarate reductase, but not saccharopine dehydrogenase, is subject to substrate inhibition in pig liver. Nutrition research (New York, N.Y.) 20110701
Complete genome sequence of Rhodospirillum rubrum type strain (S1). Standards in genomic sciences 20110701
The disruption of L-carnitine metabolism by aluminum toxicity and oxidative stress promotes dyslipidemia in human astrocytic and hepatic cells. Toxicology letters 20110624
A zinc finger protein, TbZC3H20, stabilizes two developmentally regulated mRNAs in trypanosomes. The Journal of biological chemistry 20110610
X-ray absorption spectroscopy structural investigation of early intermediates in the mechanism of DNA repair by human ABH2. Biochemistry 20110607
2-difluoromethylene-4-methylenepentanoic acid, a paradoxical probe able to mimic the signaling role of 2-oxoglutaric acid in cyanobacteria. Organic letters 20110603
Vernonia cinerea Less. inhibits tumor cell invasion and pulmonary metastasis in C57BL/6 mice. Integrative cancer therapies 20110601
The correlations between TCA-glyoxalate metabolite and antibiotic production of Streptomyces sp. M4018 grown in glycerol, glucose, and starch mediums. Applied biochemistry and biotechnology 20110601
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Transient excretion of succinate from Trichoderma atroviride submerged mycelia reveals the complex movements and metabolism of carboxylates. Antonie van Leeuwenhoek 20110601
Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor. Molecular pharmacology 20110601
Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy. Journal of neurochemistry 20110601
(R,S)-dichlorprop herbicide in agricultural soil induces proliferation and expression of multiple dioxygenase-encoding genes in the indigenous microbial community. Environmental microbiology 20110601
Actinotrichia collagens and their role in fin formation. Developmental biology 20110601
Structural basis of fumarate hydratase deficiency. Journal of inherited metabolic disease 20110601
Chronic alcoholism in rats induces a compensatory response, preserving brain thiamine diphosphate, but the brain 2-oxo acid dehydrogenases are inactivated despite unchanged coenzyme levels. Journal of neurochemistry 20110601
A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation. PLoS genetics 20110601
H NMR spectroscopy-based metabolomic assessment of uremic toxicity, with toxicological outcomes, in male rats following an acute, mid-life insult from ochratoxin a. Toxins 20110601
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[Study on influence of glucoside Tripterygium total tablets on metabolism in rats by NMR metabonomic technique]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601
Expression and functional analysis of glutamate synthase small subunit-like proteins from archaeon Pyrococcus horikoshii. Microbiological research 20110520
Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex. The Journal of biological chemistry 20110520
Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase. Biochemical and biophysical research communications 20110520
Vitamin C is dispensable for oxygen sensing in vivo. Blood 20110519
Two antioxidants are better than one. Blood 20110519
Observation of two families of folding pathways of BBL. Biophysical journal 20110518
Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells. Molecular and cellular endocrinology 20110516
Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia. Journal of proteome research 20110506
Metabolic reprogramming by HIF-1 promotes the survival of bone marrow-derived angiogenic cells in ischemic tissue. Blood 20110505
Substrate specificity of 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum: toward a bio-based production of adipic acid. Biochemistry 20110503
Inhibition of histone demethylases by 4-carboxy-2,2'-bipyridyl compounds. ChemMedChem 20110502
Rosette-forming glioneuronal tumor: a pineal region case with IDH1 and IDH2 mutation analyses and literature review of 43 cases. Journal of neuro-oncology 20110501
Cervical softening during pregnancy: regulated changes in collagen cross-linking and composition of matricellular proteins in the mouse. Biology of reproduction 20110501
Could thiamine pyrophosphate be a regulator of the nitric oxide synthesis in the endothelial cell of diabetic patients? Medical hypotheses 20110501
The tricarboxylic acid cycle in L₃ Teladorsagia circumcincta: metabolism of acetyl CoA to succinyl CoA. Experimental parasitology 20110501
Identification of urinary biomarkers from X-irradiated mice using NMR spectroscopy. Radiation research 20110501
Urine metabolomic analysis identifies potential biomarkers and pathogenic pathways in kidney cancer. Omics : a journal of integrative biology 20110501
Three 2-oxoglutarate-dependent dioxygenase activities of Equisetum arvense L. forming flavone and flavonol from (2S)-naringenin. Phytochemistry 20110501
Deamination role of inducible glutamate dehydrogenase isoenzyme 7 in Brassica napus leaf protoplasts. Phytochemistry 20110501
Multienzyme-modified biosensing surface for the electrochemical analysis of aspartate transaminase and alanine transaminase in human plasma. Analytical and bioanalytical chemistry 20110501
Uncoupled O2-activation in the human HIF-asparaginyl hydroxylase, FIH, does not produce reactive oxygen species. Journal of inorganic biochemistry 20110501
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO reports 20110501
Effect of acute hypoglycemia on human cerebral glucose metabolism measured by ¹³C magnetic resonance spectroscopy. Diabetes 20110501
Genetic factors in isolated and syndromic esophageal atresia. Journal of pediatric gastroenterology and nutrition 20110501
Magnetic resonance spectroscopy studies of human metabolism. Diabetes 20110501
Os-GIGANTEA confers robust diurnal rhythms on the global transcriptome of rice in the field. The Plant cell 20110501
Genome of Herbaspirillum seropedicae strain SmR1, a specialized diazotrophic endophyte of tropical grasses. PLoS genetics 20110501
Development of nano alpha-ketoglutarate nebulization formulation and its pharmacokinetic and safety evaluation in healthy human volunteers for cyanide poisoning. Environmental toxicology and pharmacology 20110501
Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes. Human molecular genetics 20110415
Development of amperometric α-ketoglutarate biosensor based on ruthenium-rhodium modified carbon fiber enzyme microelectrode. Biosensors & bioelectronics 20110415
Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors. The Journal of biological chemistry 20110415
The last step of the biosynthesis of the cyanotoxins cylindrospermopsin and 7-epi-cylindrospermopsin is catalysed by CyrI, a 2-Oxoglutarate-dependent iron oxygenase. Chembiochem : a European journal of chemical biology 20110411
Biochemical diagnosis of mitochondrial disorders. Journal of inherited metabolic disease 20110401
Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production. Amino acids 20110401
Papillary thyroid carcinoma shows elevated levels of 2-hydroxyglutarate. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110401
A gold nanoparticle-mediated enzyme bioreactor for inhibitor screening by capillary electrophoresis. Analytical biochemistry 20110401
¹H-NMR-based metabonomic analysis of metabolic profiling in diabetic nephropathy rats induced by streptozotocin. American journal of physiology. Renal physiology 20110401
Redox signaling in cardiac myocytes. Free radical biology & medicine 20110401
The sodium-dependent di- and tricarboxylate transporter, NaCT, is not responsible for the uptake of D-, L-2-hydroxyglutarate and 3-hydroxyglutarate into neurons. Journal of inherited metabolic disease 20110401
Isocitrate dehydrogenase mutations may be a protective mechanism in glioma patients. Medical hypotheses 20110401
The influence of diabetes on glutamate metabolism in retinas. Journal of neurochemistry 20110401
Plant D-2-hydroxyglutarate dehydrogenase participates in the catabolism of lysine especially during senescence. The Journal of biological chemistry 20110401
Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis. Cancer research 20110401
Cloning, expression and characterization of a new aspartate aminotransferase from Bacillus subtilis B3. The FEBS journal 20110401
Metabolic characterization of Palatinate German white wines according to sensory attributes, varieties, and vintages using NMR spectroscopy and multivariate data analyses. Journal of biomolecular NMR 20110401
Role of aminotransferases in glutamate metabolism of human erythrocytes. Journal of biomolecular NMR 20110401
A sister group contrast using untargeted global metabolomic analysis delineates the biochemical regulation underlying desiccation tolerance in Sporobolus stapfianus. The Plant cell 20110401
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS. PLoS biology 20110401
The neuroprotective effect of 2-oxoglutarate in the experimental ischemia of hippocampus. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110401
Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis. British journal of cancer 20110329
Lysyl hydroxylase 3 glucosylates galactosylhydroxylysine residues in type I collagen in osteoblast culture. The Journal of biological chemistry 20110318
Regulation of erythropoietin production. The Journal of physiology 20110315
Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4. The Biochemical journal 20110315
Protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism. The Journal of biological chemistry 20110311
Characterization of LipL as a non-heme, Fe(II)-dependent α-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis. The Journal of biological chemistry 20110311
Biochemical and structural characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid. Biochemistry 20110308
The 2-oxoglutarate-dependent oxygenase JMJD6 catalyses oxidation of lysine residues to give 5S-hydroxylysine residues. Chembiochem : a European journal of chemical biology 20110307
Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor. The Journal of biological chemistry 20110304
Artefacts in cell culture: α-Ketoglutarate can scavenge hydrogen peroxide generated by ascorbate and epigallocatechin gallate in cell culture media. Biochemical and biophysical research communications 20110304
Dioxygenases, key enzymes to determine the aglycon structures of fusicoccin and brassicicene, diterpene compounds produced by fungi. Journal of the American Chemical Society 20110302
Overexpression of alpha-ketoglutarate dehydrogenase in Yarrowia lipolytica and its effect on production of organic acids. Applied microbiology and biotechnology 20110301
Application of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthase. Analytical biochemistry 20110301
Nitrate regulates floral induction in Arabidopsis, acting independently of light, gibberellin and autonomous pathways. Planta 20110301
Abnormalities in the tricarboxylic acid (TCA) cycle in the brains of schizophrenia patients. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20110301
Functional and structural role of amino acid residues in the matrix alpha-helices, termini and cytosolic loops of the bovine mitochondrial oxoglutarate carrier. Biochimica et biophysica acta 20110301
Effect of alpha-ketoglutarate on neurobehavioral, neurochemical and oxidative changes caused by sub-chronic cyanide poisoning in rats. Neurochemical research 20110301
The rate of nitrite reduction in leaves as indicated by O₂ and CO₂ exchange during photosynthesis. Journal of experimental botany 20110301
Thiamine-responsive megaloblastic anemia syndrome with atrial standstill: a case report. Journal of pediatric hematology/oncology 20110301
Inborn and acquired metabolic defects in cancer. Journal of molecular medicine (Berlin, Germany) 20110301
[Facial dysmorphism associated with ketoglutaric acid]. Anales de pediatria (Barcelona, Spain : 2003) 20110301
Resolving the TCA cycle and pentose-phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis. Biotechnology journal 20110301
Effects of polynitrogen compounds on the activity of recombinant human HIF-1α prolyl hydroxylase 3 in E. coli. Journal of inorganic biochemistry 20110301
Does early treatment prevent deafness in thiamine-responsive megaloblastic anaemia syndrome? Journal of clinical research in pediatric endocrinology 20110301
Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells. PLoS computational biology 20110301
[Metabolic pathways of OGCP and the influence of parkin protein on the metabolism of OGCP]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110301
Studies on substrate specificity of Jmjd2a-c histone demethylases. Biochemical and biophysical research communications 20110225
Ataxia telangiectasia mutated influences cytochrome c oxidase activity. Biochemical and biophysical research communications 20110225
Structural basis for human PHF2 Jumonji domain interaction with metal ions. Journal of molecular biology 20110211
Systems responses of rats to aflatoxin B1 exposure revealed with metabonomic changes in multiple biological matrices. Journal of proteome research 20110204
Hesperidin attenuates mitochondrial dysfunction during benzo(a)pyrene-induced lung carcinogenesis in mice. Fundamental & clinical pharmacology 20110201
Vibrio communis sp. nov., isolated from the marine animals Mussismilia hispida, Phyllogorgia dilatata, Palythoa caribaeorum, Palythoa variabilis and Litopenaeus vannamei. International journal of systematic and evolutionary microbiology 20110201
Prolonged cold storage using a new histidine-tryptophan-ketoglutarate-based preservation solution in isogeneic cardiac mouse grafts. European heart journal 20110201
Clinical, genetic and magnetic resonance findings in an Italian patient affected by L-2-hydroxyglutaric aciduria. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110201
Immunoreactive Coxiella burnetii Nine Mile proteins separated by 2D electrophoresis and identified by tandem mass spectrometry. Microbiology (Reading, England) 20110201
Effects of CaCl2 on viscosity of culture broth, and on activities of enzymes around the 2-oxoglutarate branch, in Bacillus subtilis CGMCC 2108 producing poly-(γ-glutamic acid). Bioresource technology 20110201
Autoantibodies to GW bodies and other autoantigens in primary biliary cirrhosis. Clinical and experimental immunology 20110201
Regulation of muscular glutamate metabolism by high-protein diet in broiler chicks. Animal science journal = Nihon chikusan Gakkaiho 20110201
Respiration and nitrogen assimilation: targeting mitochondria-associated metabolism as a means to enhance nitrogen use efficiency. Journal of experimental botany 20110201
Regulation of nitrate assimilation in cyanobacteria. Journal of experimental botany 20110201
Structure of GlnK1, a signalling protein from Archaeoglobus fulgidus. Acta crystallographica. Section F, Structural biology and crystallization communications 20110201
Antisense inhibition of the iron-sulphur subunit of succinate dehydrogenase enhances photosynthesis and growth in tomato via an organic acid-mediated effect on stomatal aperture. The Plant cell 20110201
Alpha-ketoglutarate stabilizes redox homeostasis and improves arterial elasticity in aged mice. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201
Prevention of cadmium bioaccumulation by herbal adaptogens. Indian journal of pharmacology 20110201
Specific inhibition of the aspartate aminotransferase of Plasmodium falciparum. Journal of molecular biology 20110128
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer cell 20110118
Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates. Organic & biomolecular chemistry 20110107
Global metabolic phenotyping in an experimental laparotomy model of surgical trauma. Journal of proteome research 20110107
Robust control of nitrogen assimilation by a bifunctional enzyme in E. coli. Molecular cell 20110107
Metabonomic investigation of single and multiple strain Trypanosoma brucei brucei infections. The American journal of tropical medicine and hygiene 20110105
Protective effects of chinese traditional medicine buyang huanwu decoction on myocardial injury. Evidence-based complementary and alternative medicine : eCAM 20110101
An mRNA blueprint for C4 photosynthesis derived from comparative transcriptomics of closely related C3 and C4 species. Plant physiology 20110101
Glutamate synthase, but not GABA shunt enzymes, contributes to nitrogen metabolism of the sheep abomasal nematode parasites Haemonchus contortus and Teladorsagia circumcincta. Experimental parasitology 20110101
Identification of up-regulated genes of Bacillus amyloliquefaciens B55 during the early stage of direct surface contact with rice R109 root. Current microbiology 20110101
Gene expression patterns in bone following mechanical loading. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110101
Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases. Trends in biochemical sciences 20110101
Characterisation of the Drosophila procollagen lysyl hydroxylase, dPlod. Gene expression patterns : GEP 20110101
Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I. Brain : a journal of neurology 20110101
Nitrogen metabolism responses to water deficit act through both abscisic acid (ABA)-dependent and independent pathways in Medicago truncatula during post-germination. Journal of experimental botany 20110101
Dimerization of human lysyl hydroxylase 3 (LH3) is mediated by the amino acids 541-547. Matrix biology : journal of the International Society for Matrix Biology 20110101
Prooxidant activity of fisetin: effects on energy metabolism in the rat liver. Journal of biochemical and molecular toxicology 20110101
Brain glutamine synthesis requires neuronal aspartate: a commentary. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110101
Post-translational modifications in secreted peptide hormones in plants. Plant & cell physiology 20110101
Differential toxicological effects induced by mercury in gills from three pedigrees of Manila clam Ruditapes philippinarum by NMR-based metabolomics. Ecotoxicology (London, England) 20110101
Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data. Bioinformatics (Oxford, England) 20110101
α-Ketoglutarate dehydrogenase: a mitochondrial redox sensor. Free radical research 20110101
HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies. Analytical chemistry 20110101
Histone deacetylase inhibitors: the epigenetic therapeutics that repress hypoxia-inducible factors. Journal of biomedicine & biotechnology 20110101
The chloroplastic 2-oxoglutarate/malate transporter has dual function as the malate valve and in carbon/nitrogen metabolism. The Plant journal : for cell and molecular biology 20110101
[Galactosemia associated with Rogers syndrome in a 10-month-old infant]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20110101
Alpha-Ketoglutarate and intestinal function. Frontiers in bioscience (Landmark edition) 20110101
Metabolic pathway engineering based on metabolomics confers acetic and formic acid tolerance to a recombinant xylose-fermenting strain of Saccharomyces cerevisiae. Microbial cell factories 20110101
SPABBATS: A pathway-discovery method based on Boolean satisfiability that facilitates the characterization of suppressor mutants. BMC systems biology 20110101
Role of PII proteins in nitrogen fixation control of Herbaspirillum seropedicae strain SmR1. BMC microbiology 20110101
Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets? International journal of biological sciences 20110101
Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection. Parkinson's disease 20110101
Malate plays a crucial role in starch metabolism, ripening, and soluble solid content of tomato fruit and affects postharvest softening. The Plant cell 20110101
De novo designed proteins from a library of artificial sequences function in Escherichia coli and enable cell growth. PloS one 20110101
Method development and validation for the analysis of a new anti-cancer infusion solution via HPLC. Journal of separation science 20110101
Cardiogenol C can induce Mouse Hair Bulge Progenitor Cells to Transdifferentiate into Cardiomyocyte-like Cells. Proteome science 20110101
Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease. Molecular neurodegeneration 20110101
Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α). PloS one 20110101
Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases. Journal of biomedicine & biotechnology 20110101
Flux balance analysis of ammonia assimilation network in E. coli predicts preferred regulation point. PloS one 20110101
Modulation of the major paths of carbon in photorespiratory mutants of synechocystis. PloS one 20110101
A day in the life of microcystis aeruginosa strain PCC 7806 as revealed by a transcriptomic analysis. PloS one 20110101
Essential metabolites of Mycobacterium tuberculosis and their mimics. mBio 20110101
The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen. Breast cancer research : BCR 20110101
Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling. Journal of clinical biochemistry and nutrition 20110101
Carbon monoxide stimulates global protein methylation via its inhibitory action on cystathionine β-synthase. Journal of clinical biochemistry and nutrition 20110101
Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. PloS one 20110101
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1. PloS one 20110101
Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase. Enzyme research 20110101
2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations. PloS one 20110101
Development of proteomics-based fungicides: new strategies for environmentally friendly control of fungal plant diseases. International journal of molecular sciences 20110101
Colonization-induced host-gut microbial metabolic interaction. mBio 20110101
An effective assessment of simvastatin-induced toxicity with NMR-based metabonomics approach. PloS one 20110101
Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer. BMC cancer 20110101
2-oxoacid metabolism in methanogenic CoM and CoB biosynthesis. Methods in enzymology 20110101
Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease. Retrovirology 20110101
Analysis of the ArcA regulon in anaerobically grown Salmonella enterica sv. Typhimurium. BMC microbiology 20110101
Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses. International journal of Alzheimer's disease 20110101
Metabolome in schizophrenia and other psychotic disorders: a general population-based study. Genome medicine 20110101
Proteomic Profiling of Mitochondrial Enzymes during Skeletal Muscle Aging. Journal of aging research 20110101
Genome sequence of the stramenopile Blastocystis, a human anaerobic parasite. Genome biology 20110101
MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion. PloS one 20110101
Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli. Molecular systems biology 20110101
Hypoxia-inducible factors and the prevention of acute organ injury. Critical care (London, England) 20110101
Amyloid-Beta interaction with mitochondria. International journal of Alzheimer's disease 20110101
Directed culturing of microorganisms using metatranscriptomics. mBio 20110101
p53 Regulates oxidative stress-mediated retrograde signaling: a novel mechanism for chemotherapy-induced cardiac injury. PloS one 20110101
A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress. BMC systems biology 20110101
Natural history of eukaryotic DNA methylation systems. Progress in molecular biology and translational science 20110101
Revealing the beneficial effect of protease supplementation to high gravity beer fermentations using '-omics' techniques. Microbial cell factories 20110101
Transcriptomic analysis of milk somatic cells in mastitis resistant and susceptible sheep upon challenge with Staphylococcus epidermidis and Staphylococcus aureus. BMC genomics 20110101
A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population. Molecular vision 20110101
A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine. Malaria journal 20110101
Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. PloS one 20110101
Quantal amplitude at the cone ribbon synapse can be adjusted by changes in cytosolic glutamate. Molecular vision 20110101
A new crystal form of mouse thiamin pyrophosphokinase. International journal of biochemistry and molecular biology 20110101
The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. PloS one 20110101
Absence of aquaporin-4 in skeletal muscle alters proteins involved in bioenergetic pathways and calcium handling. PloS one 20110101
More than 200 genes required for methane formation from H₂ and CO₂ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus. Archaea (Vancouver, B.C.) 20110101
Design of an efficient medium for heterologous protein production in Yarrowia lipolytica: case of human interferon alpha 2b. Microbial cell factories 20110101
Metabolic regulation of Escherichia coli and its phoB and phoR genes knockout mutants under phosphate and nitrogen limitations as well as at acidic condition. Microbial cell factories 20110101
Do somatic mitochondrial DNA mutations contribute to Parkinson's disease? Parkinson's disease 20110101
Symbolic flux analysis for genome-scale metabolic networks. BMC systems biology 20110101
Identification of prognostic molecular features in the reactive stroma of human breast and prostate cancer. PloS one 20110101
Protein coalitions in a core mammalian biochemical network linked by rapidly evolving proteins. BMC evolutionary biology 20110101
Path finding methods accounting for stoichiometry in metabolic networks. Genome biology 20110101
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma. PloS one 20110101
Comparative transcriptome analysis of Bacillus subtilis responding to dissolved oxygen in adenosine fermentation. PloS one 20110101
The Involvement of Glutamate Metabolism in the Resistance to Thermal, Nutritional, and Oxidative Stress in Trypanosoma cruzi. Enzyme research 20110101
Novel insights into the diversity of catabolic metabolism from ten haloarchaeal genomes. PloS one 20110101
L,L-diaminopimelate aminotransferase from Chlamydomonas reinhardtii: a target for algaecide development. PloS one 20110101
The metabolic advantage of tumor cells. Molecular cancer 20110101
Evaluation of formalin-fixed paraffin-embedded tissues in the proteomic analysis of parathyroid glands. Proteome science 20110101
MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes. PloS one 20110101
Identification of novel soybean microRNAs involved in abiotic and biotic stresses. BMC genomics 20110101
Discrimination of individuals in a general population at high-risk for alcoholic and non-alcoholic fatty liver disease based on liver stiffness: a cross section study. BMC gastroenterology 20110101
Expression of hypoxia-inducible factors, regulators, and target genes in congenital diaphragmatic hernia patients. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 20110101
Multi-locus sequence typing of Salmonella enterica subsp. enterica serovar Enteritidis strains in Japan between 1973 and 2004. Acta veterinaria Scandinavica 20110101
The biological deep sea hydrothermal vent as a model to study carbon dioxide capturing enzymes. Marine drugs 20110101
Carotenoid β-ring hydroxylase and ketolase from marine bacteria-promiscuous enzymes for synthesizing functional xanthophylls. Marine drugs 20110101
Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies. PloS one 20110101
Transcriptomic, proteomic and metabolomic analysis of UV-B signaling in maize. BMC genomics 20110101
Primary biliary cirrhosis: family stories. Autoimmune diseases 20110101
5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells. Genome biology 20110101
A survey of oxidative paracatalytic reactions catalyzed by enzymes that generate carbanionic intermediates: implications for ROS production, cancer etiology, and neurodegenerative diseases. Advances in enzymology and related areas of molecular biology 20110101
Economics of membrane occupancy and respiro-fermentation. Molecular systems biology 20110101
Simplivariate models: uncovering the underlying biology in functional genomics data. PloS one 20110101
Phenotypic variability of the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA): clinical, molecular and biochemical delineation. Orphanet journal of rare diseases 20110101
Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission. PloS one 20110101
Impairment of adult hippocampal neural progenitor proliferation by methamphetamine: role for nitrotyrosination. Molecular brain 20110101
Directional RNA deep sequencing sheds new light on the transcriptional response of Anabaena sp. strain PCC 7120 to combined-nitrogen deprivation. BMC genomics 20110101
General metabolism of Laribacter hongkongensis: a genome-wide analysis. Cell & bioscience 20110101
Compartmentalized Cerebral Metabolism of [1,6-(13)C]Glucose Determined by in vivo (13)C NMR Spectroscopy at 14.1 T. Frontiers in neuroenergetics 20110101
A metabolic model of the mitochondrion and its use in modelling diseases of the tricarboxylic acid cycle. BMC systems biology 20110101
Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease. Alzheimer's research & therapy 20110101
A minimal model for the mitochondrial rapid mode of Ca²+ uptake mechanism. PloS one 20110101
Dynamic changes of the phosphoproteome in postmortem mouse brains. PloS one 20110101
The role of the C8 proton of ATP in the regulation of phosphoryl transfer within kinases and synthetases. BMC biochemistry 20110101
Bacterial RuBisCO is required for efficient Bradyrhizobium/Aeschynomene symbiosis. PloS one 20110101
Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development. Malaria journal 20110101
Viruses and metabolism: alterations of glucose and glutamine metabolism mediated by human cytomegalovirus. Advances in virus research 20110101
The putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation. PloS one 20110101
Hypoxia-inducible factor in thyroid carcinoma. Journal of thyroid research 20110101
Proteomic analysis of an Aedes albopictus cell line infected with Dengue serotypes 1 and 3 viruses. Parasites & vectors 20110101
Detection of copy number variations in rice using array-based comparative genomic hybridization. BMC genomics 20110101
Close Interspecies Interactions between Prokaryotes from Sulfureous Environments. Frontiers in microbiology 20110101
Linking hydrothermal geochemistry to organismal physiology: physiological versatility in Riftia pachyptila from sedimented and basalt-hosted vents. PloS one 20110101
Randomizing genome-scale metabolic networks. PloS one 20110101
Activation of protein kinase C delta following cerebral ischemia leads to release of cytochrome C from the mitochondria via bad pathway. PloS one 20110101
Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. PloS one 20110101
[Astroglia proteins in the rat brain in experimental chronic hepatitis and 2-oxoglutarate effect]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101
Comparative analyses imply that the enigmatic Sigma factor 54 is a central controller of the bacterial exterior. BMC genomics 20110101
Renal mitochondrial cytopathies. International journal of nephrology 20110101
A very early-branching Staphylococcus aureus lineage lacking the carotenoid pigment staphyloxanthin. Genome biology and evolution 20110101
A novel acyl-CoA beta-transaminase characterized from a metagenome. PloS one 20110101
Proteomic characterization of cellular and molecular processes that enable the Nanoarchaeum equitans--Ignicoccus hospitalis relationship. PloS one 20110101
Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella paludicola, the first cultivated representative of the order Methanocellales. PloS one 20110101
The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue. Genome biology 20110101
Epigenetics: new questions on the response to hypoxia. International journal of molecular sciences 20110101
Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052. BMC systems biology 20110101
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth. Molecular systems biology 20110101
Legionella pneumophila serogroup 3 pneumonia in a patient with low-grade 4 non-Hodgkin lymphoma: a case report. Journal of medical case reports 20110101
Molecular characterization of transcriptome-wide interactions between highly pathogenic porcine reproductive and respiratory syndrome virus and porcine alveolar macrophages in vivo. International journal of biological sciences 20110101
Association between markers of fatty liver disease and impaired glucose regulation in men and women from the general population: the KORA-F4-study. PloS one 20110101
Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104. PloS one 20110101
Deletion of UCP2 in iNOS deficient mice reduces the severity of the disease during experimental autoimmune encephalomyelitis. PloS one 20110101
Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: a tangible union against chemoresistant cancer. BMC cancer 20110101
The glutamine synthetase gene family in Populus. BMC plant biology 20110101
Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment. Breast cancer research : BCR 20110101
An Examination by Site-Directed Mutagenesis of Putative Key Residues in the Determination of Coenzyme Specificity in Clostridial NAD-Dependent Glutamate Dehydrogenase. Enzyme research 20110101
Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus. BMC microbiology 20110101
Recombining low homology, functionally rich regions of bacterial subtilisins by combinatorial fragment exchange. PloS one 20110101
Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni. Parasites & vectors 20110101
Analysis of the BarA/UvrY two-component system in Shewanella oneidensis MR-1. PloS one 20110101
Analysis of hypoxia and hypoxia-like states through metabolite profiling. PloS one 20110101
A comprehensive metabolic profile of cultured astrocytes using isotopic transient metabolic flux analysis and C-labeled glucose. Frontiers in neuroenergetics 20110101
Severe encephalopathy, lactic acidosis, vegetative instability and neuropathy with 5-Fluorouracil treatment - pyrimidine degradation defect or beriberi? Case reports in oncology 20110101
Unveiling novel genes upregulated by both rhBMP2 and rhBMP7 during early osteoblastic transdifferentiation of C2C12 cells. BMC research notes 20110101
Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase. BMC biochemistry 20110101
The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR. PloS one 20110101
Large-scale bi-level strain design approaches and mixed-integer programming solution techniques. PloS one 20110101
Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones. PloS one 20110101
Gene expression profile of the cartilage tissue spontaneously regenerated in vivo by using a novel double-network gel: comparisons with the normal articular cartilage. BMC musculoskeletal disorders 20110101
Gibberellin A1 metabolism contributes to the control of photoperiod-mediated tuberization in potato. PloS one 20110101
Chemical biology of lysine demethylases. Current chemical genomics 20110101
Methods for Activity Analysis of the Proteins that Regulate Histone Methylation. Current chemical genomics 20110101
D-ribose induces cellular protein glycation and impairs mouse spatial cognition. PloS one 20110101
Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats. Acta cirurgica brasileira 20110101
Differential expression of three flavanone 3-hydroxylase genes in grains and coleoptiles of wheat. International journal of plant genomics 20110101
Reprogramming of Escherichia coli K-12 metabolism during the initial phase of transition from an anaerobic to a micro-aerobic environment. PloS one 20110101
Modes of metabolic compensation during mitochondrial disease using the Drosophila model of ATP6 dysfunction. PloS one 20110101
Temporal transcriptome changes induced by MDV in Marek's disease-resistant and -susceptible inbred chickens. BMC genomics 20110101
Astrocyte-neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions--in silico study supported by in vitro expression data. BMC systems biology 20110101
An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92. BMC systems biology 20110101
MetaboHunter: an automatic approach for identification of metabolites from 1H-NMR spectra of complex mixtures. BMC bioinformatics 20110101
Horizontal and vertical growth of S. cerevisiae metabolic network. BMC evolutionary biology 20110101
Critical assessment of human metabolic pathway databases: a stepping stone for future integration. BMC systems biology 20110101
Lipoic acid - biological activity and therapeutic potential. Pharmacological reports : PR 20110101
The complete genome sequence of Thermoproteus tenax: a physiologically versatile member of the Crenarchaeota. PloS one 20110101
Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread. Nutrition journal 20110101
Proteomic and biochemical analyses reveal the activation of unfolded protein response, ERK-1/2 and ribosomal protein S6 signaling in experimental autoimmune myocarditis rat model. BMC genomics 20110101
Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity. PloS one 20110101
Antitubercular effect of 8-[(4-Chloro phenyl) sulfonyl]-7-Hydroxy-4-Methyl-2H-chromen-2-One in guinea pigs. Journal of pharmacology & pharmacotherapeutics 20110101
Changes in cardiac substrate transporters and metabolic proteins mirror the metabolic shift in patients with aortic stenosis. PloS one 20110101
Clinical proteomics of the neglected human malarial parasite Plasmodium vivax. PloS one 20110101
Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control. Malaria journal 20110101
Mechanism of disruption of the Amt-GlnK complex by P(II)-mediated sensing of 2-oxoglutarate. PloS one 20110101
Differential responses of the coral host and their algal symbiont to thermal stress. PloS one 20110101
Paromomycin affects translation and vesicle-mediated trafficking as revealed by proteomics of paromomycin -susceptible -resistant Leishmania donovani. PloS one 20110101
Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. International journal of molecular sciences 20110101
Metal-induced oxidative stress and plant mitochondria. International journal of molecular sciences 20110101
Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System. Clinical Medicine Insights. Oncology 20110101
Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells. PloS one 20110101
Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases. Cold Spring Harbor symposia on quantitative biology 20110101
Effect of intravenous GLutamine supplementation IN Trauma patients receiving enteral nutrition study protocol (GLINT Study): a prospective, blinded, randomised, placebo-controlled clinical trial. BMJ open 20110101
GNC and CGA1 modulate chlorophyll biosynthesis and glutamate synthase (GLU1/Fd-GOGAT) expression in Arabidopsis. PloS one 20110101
An engineered pathway for glyoxylate metabolism in tobacco plants aimed to avoid the release of ammonia in photorespiration. BMC biotechnology 20110101
Potential biomarkers in mouse myocardium of doxorubicin-induced cardiomyopathy: a metabonomic method and its application. PloS one 20110101
Sequence of the hyperplastic genome of the naturally competent Thermus scotoductus SA-01. BMC genomics 20110101
[Importance of preservation of biophysical organization of isolated mitochondria for revealing physiological regulation of their functions]. Biofizika 20110101
Biomarkers of acute kidney injury. Journal of toxicology 20110101
Dynamic proteomic profiling of a unicellular cyanobacterium Cyanothece ATCC51142 across light-dark diurnal cycles. BMC systems biology 20110101
In vitro prevention of cataract by Oyster Mushroom Pleurotus florida extract on isolated goat eye lens. Indian journal of pharmacology 20110101
The metabolic reprogramming evoked by nitrosative stress triggers the anaerobic utilization of citrate in Pseudomonas fluorescens. PloS one 20110101
A HNMR-based metabonomics study of postmenopausal osteoporosis and intervention effects of Er-Xian Decoction in ovariectomized rats. International journal of molecular sciences 20110101
Radiation-induced signaling results in mitochondrial impairment in mouse heart at 4 weeks after exposure to X-rays. PloS one 20110101
Genome characterization of the oleaginous fungus Mortierella alpina. PloS one 20110101
Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes. PloS one 20110101
Correlation of gene expression and protein production rate - a system wide study. BMC genomics 20110101
Increasing the source/sink ratio in Vitis vinifera (cv Sangiovese) induces extensive transcriptome reprogramming and modifies berry ripening. BMC genomics 20110101
Chronic deficiency of nitric oxide affects hypoxia inducible factor-1α (HIF-1α) stability and migration in human endothelial cells. PloS one 20110101
[2-Oxoglutarate dehydrogenase complex and its multipoint control]. Postepy biochemii 20110101
Tertiary alcohol preferred: Hydroxylation of trans-3-methyl-L-proline with proline hydroxylases. Beilstein journal of organic chemistry 20110101
[Ultrastructure of coronary microvessels in conditions of heart reperfusion following prolonged ischemia while applying various methods of artificial hypothermia]. Tsitologiia 20110101
Amino acids biosynthesis and nitrogen assimilation pathways: a great genomic deletion during eukaryotes evolution. BMC genomics 20110101
Molecular mechanisms regulating macrophage response to hypoxia. Frontiers in immunology 20110101
Integrated genomic analysis of sézary syndrome. Genetics research international 20110101
Metabolite Signature during Short-Day Induced Growth Cessation in Populus. Frontiers in plant science 20110101
The Plastid Outer Envelope - A Highly Dynamic Interface between Plastid and Cytoplasm. Frontiers in plant science 20110101
From models to crop species: caveats and solutions for translational metabolomics. Frontiers in plant science 20110101
Detecting functional groups of Arabidopsis mutants by metabolic profiling and evaluation of pleiotropic responses. Frontiers in plant science 20110101
Common Motifs in the Response of Cereal Primary Metabolism to Fungal Pathogens are not Based on Similar Transcriptional Reprogramming. Frontiers in plant science 20110101
The metabolite transporters of the plastid envelope: an update. Frontiers in plant science 20110101
Metabolite profile changes in xylem sap and leaf extracts of strategy I plants in response to iron deficiency and resupply. Frontiers in plant science 20110101
FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More? Frontiers in endocrinology 20110101
Past, present, and future of molecular and cellular oncology. Frontiers in oncology 20110101
Exploring the molecular and metabolic factors contributing to the adaptation of maize seedlings to nitrate limitation. Frontiers in plant science 20110101
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509). Standards in genomic sciences 20101231
Structural and mechanistic studies on γ-butyrobetaine hydroxylase. Chemistry & biology 20101222
IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status. Blood 20101216
von Hippel-Lindau β-domain-luciferase fusion protein as a bioluminescent hydroxyproline sensor for a hypoxia-inducible factor prolyl hydroxylase assay. Analytical biochemistry 20101215
Cancer-associated IDH mutations: biomarker and therapeutic opportunities. Oncogene 20101209
Reversible adenylylation of glutamine synthetase is dynamically counterbalanced during steady-state growth of Escherichia coli. Journal of molecular biology 20101203
In vitro activity of antimicrobial agents against Legionella isolated from environmental water systems: first results from Turkey. Environmental monitoring and assessment 20101201
Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201
Effects of ranolazine on fatty acid transformation in the isolated perfused rat liver. Molecular and cellular biochemistry 20101201
Transcriptome atlas of glutamine family amino acid metabolism-related genes in eight regenerating liver cell types. Cell biology international 20101201
Toxicometabolomics approach to urinary biomarkers for mercuric chloride (HgCl₂)-induced nephrotoxicity using proton nuclear magnetic resonance (¹H NMR) in rats. Toxicology and applied pharmacology 20101201
Pyruvate carboxylation in different model systems studied by (13)C MRS. Neurochemical research 20101201
Acetyl-CoA deficit in brain mitochondria in experimental thiamine deficiency encephalopathy. Neurochemistry international 20101201
Dietary keto-acid feed-back on pituitary activity in gilthead sea bream: effects of oral doses of AKG. A proteomic approach. General and comparative endocrinology 20101201
Flavonoid rich fraction of Dioscorea bulbifera Linn. (Yam) enhances mitochondrial enzymes and antioxidant status and thereby protects heart from isoproterenol induced myocardial infarction. Current pharmaceutical biotechnology 20101201
Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia. Molecular genetics and genomics : MGG 20101201
Structural studies on human 2-oxoglutarate dependent oxygenases. Current opinion in structural biology 20101201
Biochemical and structural characterization of recombinant hyoscyamine 6β-hydroxylase from Datura metel L. Plant physiology and biochemistry : PPB 20101201
Linking the salt transcriptome with physiological responses of a salt-resistant Populus species as a strategy to identify genes important for stress acclimation. Plant physiology 20101201
Structural insights into histone lysine demethylation. Current opinion in structural biology 20101201
Fine quantitative trait loci mapping of carbon and nitrogen metabolism enzyme activities and seedling biomass in the maize IBM mapping population. Plant physiology 20101201
Reduced placental prolyl hydroxylase 3 mRNA expression in pregnancies affected by fetal growth restriction. BJOG : an international journal of obstetrics and gynaecology 20101201
Light-enhanced catalysis by pyridoxal phosphate-dependent aspartate aminotransferase. Journal of the American Chemical Society 20101201
Dose dependent in vivo metabolic characteristics of titanium dioxide nanoparticles. Journal of nanoscience and nanotechnology 20101201
Analysis of isocitrate dehydrogenase-1/2 gene mutations in gliomas. Chinese medical journal 20101201
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. Cancer research 20101115
T3 affects expression of collagen I and collagen cross-linking in bone cell cultures. Biochemical and biophysical research communications 20101112
Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. Nature 20101111
1H NMR-based metabonomic investigation of tributyl phosphate exposure in rats. Toxicology letters 20101110
The nonribosomal peptide synthetase enzyme DdaD tethers N(β)-fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-ketoglutarate-dependent epoxidation by DdaC during dapdiamide antibiotic biosynthesis. Journal of the American Chemical Society 20101110
A glimpse at regulation of nitrogen homeostasis. Structure (London, England : 1993) 20101110
Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR. Structure (London, England : 1993) 20101110
The effect of electrostatics on the marginal cooperativity of an ultrafast folding protein. The Journal of biological chemistry 20101105
Multiple turnovers of the nicotino-enzyme PdxB require α-keto acids as cosubstrates. Biochemistry 20101102
Methylophilus flavus sp. nov. and Methylophilus luteus sp. nov., aerobic, methylotrophic bacteria associated with plants. International journal of systematic and evolutionary microbiology 20101101
Caffeic acid protects rat heart mitochondria against isoproterenol-induced oxidative damage. Cell stress & chaperones 20101101
Expression of uncoupling protein 3 in mitochondria protects against stress-induced myocardial injury: a proteomic study. Cell stress & chaperones 20101101
Mitochondrial involvement and erythronic acid as a novel biomarker in transaldolase deficiency. Biochimica et biophysica acta 20101101
The muscle fiber type-fiber size paradox: hypertrophy or oxidative metabolism? European journal of applied physiology 20101101
Genomic analysis of oceanic cyanobacterial myoviruses compared with T4-like myoviruses from diverse hosts and environments. Environmental microbiology 20101101
NMR-based metabonomic analysis of the hepatotoxicity induced by combined exposure to PCBs and TCDD in rats. Toxicology and applied pharmacology 20101101
Glucose promotion of GABA metabolism contributes to the stimulation of insulin secretion in β-cells. The Biochemical journal 20101101
The Saccharomyces cerevisiae zinc factor protein Stb5p is required as a basal regulator of the pentose phosphate pathway. FEMS yeast research 20101101
Influence of mitochondrial genome rearrangement on cucumber leaf carbon and nitrogen metabolism. Planta 20101101
The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. Plant physiology 20101101
Characterization and developmental expression of a glutamate decarboxylase from maritime pine. Planta 20101101
The JmjC domain of Gis1 is dispensable for transcriptional activation. FEMS yeast research 20101101
NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon Methanosarcina mazei Gö1. The FEBS journal 20101101
Relation between obesity and bone mineral density and vertebral fractures in Korean postmenopausal women. Yonsei medical journal 20101101
Molecular mechanisms of 'off-on switch' of activities of human IDH1 by tumor-associated mutation R132H. Cell research 20101101
Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations. Protein & cell 20101101
[Comparative study on metabonomics and on liver and kidney toxicity of Aristolochia fangchi and Stephania tetrandra]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101
Oxygen Sensing, Cardiac Ischemia, HIF-1α and Some Emerging Concepts. Current cardiology reviews 20101101
Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis. Current cardiology reviews 20101101
Transamination is required for {alpha}-ketoisocaproate but not leucine to stimulate insulin secretion. The Journal of biological chemistry 20101029
Carboxyl pK(a) values and acid denaturation of BBL. Journal of molecular biology 20101022
Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor. Bioorganic & medicinal chemistry letters 20101015
IDH2 mutations in patients with D-2-hydroxyglutaric aciduria. Science (New York, N.Y.) 20101015
Prolyl hydroxylase 3 interacts with Bcl-2 to regulate doxorubicin-induced apoptosis in H9c2 cells. Biochemical and biophysical research communications 20101015
Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase. The Journal of biological chemistry 20101008
Histone methyl transferases and demethylases; can they link metabolism and transcription? Cell metabolism 20101006
Analysis of alanine aminotransferase in various organs of soybean (Glycine max) and in dependence of different nitrogen fertilisers during hypoxic stress. Amino acids 20101001
Mild reductions in cytosolic NADP-dependent isocitrate dehydrogenase activity result in lower amino acid contents and pigmentation without impacting growth. Amino acids 20101001
Metabolic pathway of α-ketoglutarate in Lactobacillus sanfranciscensis and Lactobacillus reuteri during sourdough fermentation. Journal of applied microbiology 20101001
2-Oxoglutaric acid administration diminishes fundectomy-induced osteopenia in pigs. Journal of animal physiology and animal nutrition 20101001
Diazotrophic growth of Rhodospirillum rubrum with 2-oxoglutarate as sole carbon source affects regulation of nitrogen metabolism as well as the soluble proteome. Research in microbiology 20101001
Control of AmtB-GlnK complex formation by intracellular levels of ATP, ADP, and 2-oxoglutarate. The Journal of biological chemistry 20101001
Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain. Journal of neurochemistry 20101001
Oxidative phosphorylation is impaired by prolonged hypoxia in breast and possibly in cervix carcinoma. The international journal of biochemistry & cell biology 20101001
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism. Human molecular genetics 20101001
Metabolic engineering of Escherichia coli to produce (2S, 3R, 4S)-4-hydroxyisoleucine. Applied microbiology and biotechnology 20101001
An insight into the metabolic responses of ultra-small superparamagnetic particles of iron oxide using metabonomic analysis of biofluids. Nanotechnology 20101001
The oxoglutarate/malate carrier of rat brain mitochondria operates by a uniport exchange mechanism. Journal of bioenergetics and biomembranes 20101001
Thiamine-responsive megaloblastic anemia syndrome. International journal of hematology 20101001
Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen. The FEBS journal 20101001
Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells. Cell cycle (Georgetown, Tex.) 20101001
Quiescent fibroblasts exhibit high metabolic activity. PLoS biology 20101001
Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease. Cell death & disease 20101001
Mechanism of selective halogenation by SyrB2: a computational study. Journal of the American Chemical Society 20100922
In vitro evidence that phytanic acid compromises Na(+),K(+)-ATPase activity and the electron flow through the respiratory chain in brain cortex from young rats. Brain research 20100917
Structural and functional studies of WlbA: A dehydrogenase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid . Biochemistry 20100914
Cooperative binding of MgATP and MgADP in the trimeric P(II) protein GlnK2 from Archaeoglobus fulgidus. Journal of molecular biology 20100910
Modulating effect of Withania somnifera on TCA cycle enzymes and electron transport chain in azoxymethane-induced colon cancer in mice. Immunopharmacology and immunotoxicology 20100901
L-Tryptophan catabolism by Rubrivivax benzoatilyticus JA2 occurs through indole 3-pyruvic acid pathway. Biodegradation 20100901
Novel α-ketoglutarate dioxygenase tfdA-related genes are found in soil DNA after exposure to phenoxyalkanoic herbicides. Environmental microbiology 20100901
Diversity in mitochondrial metabolic pathways in parasitic protists Plasmodium and Cryptosporidium. Parasitology international 20100901
Composition and metabolism of carbohydrates and lipids in Sparus aurata semen and its relation to viability expressed as sperm motility when activated. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20100901
Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. Plant physiology 20100901
Screening of a thiamine-auxotrophic yeast for alpha-ketoglutaric acid overproduction. Letters in applied microbiology 20100901
Nucleotide sequence and genome organization of Dweet mottle virus and its relationship to members of the family Betaflexiviridae. Archives of virology 20100901
Force field design and molecular dynamics simulations of factor-inhibiting HIF-1 and its complex with known inhibitors: implications for rational inhibitor design. Journal of molecular graphics & modelling 20100901
IDH mutations in glioma and acute myeloid leukemia. Trends in molecular medicine 20100901
American Association for Cancer Research Genetics and Biology of Brain Cancers 2009, December 13-15, 2009, San Diego, CA. Journal of neuro-oncology 20100901
The role of mitochondria in brain aging and the effects of melatonin. Current neuropharmacology 20100901
Structural analysis of WbpE from Pseudomonas aeruginosa PAO1: a nucleotide sugar aminotransferase involved in O-antigen assembly. Biochemistry 20100824
Proline metabolism and microenvironmental stress. Annual review of nutrition 20100821
Navigating the downhill protein folding regime via structural homologues. Journal of the American Chemical Society 20100818
Interaction of JMJD6 with single-stranded RNA. Proceedings of the National Academy of Sciences of the United States of America 20100817
Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation. The Biochemical journal 20100815
Structure and reactivity of Bacillus subtilis MenD catalyzing the first committed step in menaquinone biosynthesis. Journal of molecular biology 20100813
Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6. Journal of molecular biology 20100813
OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling. FEBS letters 20100804
Consumption of pasteurized human lysozyme transgenic goats' milk alters serum metabolite profile in young pigs. Transgenic research 20100801
The sites and topology of mitochondrial superoxide production. Experimental gerontology 20100801
Biochemical characterization of pea ornithine-delta-aminotransferase: substrate specificity and inhibition by di- and polyamines. Biochimie 20100801
HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression. Journal of molecular medicine (Berlin, Germany) 20100801
OdhI dephosphorylation kinetics during different glutamate production processes involving Corynebacterium glutamicum. Applied microbiology and biotechnology 20100801
Dicarboxylate carrier-mediated glutathione transport is essential for reactive oxygen species homeostasis and normal respiration in rat brain mitochondria. American journal of physiology. Cell physiology 20100801
Histidine is a source of the antioxidant, alpha-ketoglutarate, in Pseudomonas fluorescens challenged by oxidative stress. FEMS microbiology letters 20100801
Network analysis of enzyme activities and metabolite levels and their relationship to biomass in a large panel of Arabidopsis accessions. The Plant cell 20100801
Characterizing the metabolism of Dehalococcoides with a constraint-based model. PLoS computational biology 20100801
Ornithine alpha-ketoglutarate: could it be a new therapeutic option for sarcopenia? The journal of nutrition, health & aging 20100801
Metabolic changes reveal the development of schistosomiasis in mice. PLoS neglected tropical diseases 20100801
Host imprints on bacterial genomes--rapid, divergent evolution in individual patients. PLoS pathogens 20100801
Effect of bovine serum albumin on mitochondrial respiration in the brain and liver of mice and rats. Bulletin of experimental biology and medicine 20100801
IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain. Biochemical and biophysical research communications 20100730
Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties. Journal of molecular biology 20100723
A new P(II) protein structure identifies the 2-oxoglutarate binding site. Journal of molecular biology 20100716
Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation. Journal of immunology (Baltimore, Md. : 1950) 20100715
Screening and characterization of an inhibitory chemical specific to Arabidopsis gibberellin 2-oxidases. Bioorganic & medicinal chemistry letters 20100715
Inhibition of hypoxia-inducible factor-targeting prolyl hydroxylase domain-containing protein 2 (PHD2) enhances matrix synthesis by human chondrocytes. The Journal of biological chemistry 20100702
Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts. The Journal of biological chemistry 20100702
Dietary alpha-ketoglutarate supplementation ameliorates intestinal injury in lipopolysaccharide-challenged piglets. Amino acids 20100701
Cytosolic NADP-dependent isocitrate dehydrogenase contributes to redox homeostasis and the regulation of pathogen responses in Arabidopsis leaves. Plant, cell & environment 20100701
Production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from unrelated carbon sources by metabolically engineered Escherichia coli. Metabolic engineering 20100701
Neurochemical evidence that glycine induces bioenergetical dysfunction. Neurochemistry international 20100701
An integrated imaging approach to the study of oxidative stress generation by mitochondrial dysfunction in living cells. Environmental health perspectives 20100701
Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells. The Biochemical journal 20100701
Regulation of the nitrogen transfer pathway in the arbuscular mycorrhizal symbiosis: gene characterization and the coordination of expression with nitrogen flux. Plant physiology 20100701
Increased leaf size: different means to an end. Plant physiology 20100701
WHO-defined 'myelodysplastic syndrome with isolated del(5q)' in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations. Leukemia 20100701
Metabolism of organic acids, nitrogen and amino acids in chlorotic leaves of 'Honeycrisp' apple (Malus domestica Borkh) with excessive accumulation of carbohydrates. Planta 20100701
IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis. Leukemia 20100701
Proteomic changes associated with expression of a gene (ipt) controlling cytokinin synthesis for improving heat tolerance in a perennial grass species. Journal of experimental botany 20100701
Radiolabeling and dose fixation study of oral alpha-ketoglutarate as a cyanide antidote in healthy human volunteers. Clinical toxicology (Philadelphia, Pa.) 20100701
Amish microcephaly: Long-term survival and biochemical characterization. American journal of medical genetics. Part A 20100701
Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus. PLoS pathogens 20100701
Genome-wide analysis reveals novel genes essential for heme homeostasis in Caenorhabditis elegans. PLoS genetics 20100701
[Protective effect of over-expression OGCP on HEK293 cells treated by rotenone and mutant Parkin protein]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100701
Two unrelated Chinese patients with hyperinsulinism /hyperammonemia (HI/HA) syndrome due to mutations in glutamate dehydrogenase gene. Journal of pediatric endocrinology & metabolism : JPEM 20100701
Cyanide-induced changes in the levels of neurotransmitters in discrete brain regions of rats and their response to oral treatment with alpha-ketoglutarate. Indian journal of experimental biology 20100701
2-Amino-5-methyl-pyridinium 4-carb-oxy-butano-ate. Acta crystallographica. Section E, Structure reports online 20100701
Neurological disease rises from ocean to bring model for human epilepsy to life. Toxins 20100701
Complete genome sequence of Thermosphaera aggregans type strain (M11TL). Standards in genomic sciences 20100630
Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). Standards in genomic sciences 20100630
PHD2 in tumour angiogenesis. British journal of cancer 20100629
Glioma-derived mutations in IDH: from mechanism to potential therapy. Biochemical and biophysical research communications 20100625
Transcriptome analysis and molecular signature of human retinal pigment epithelium. Human molecular genetics 20100615
Extended ischemia prevents HIF1alpha degradation at reoxygenation by impairing prolyl-hydroxylation: role of Krebs cycle metabolites. The Journal of biological chemistry 20100611
A novel signal transduction protein P(II) variant from Synechococcus elongatus PCC 7942 indicates a two-step process for NAGK-P(II) complex formation. Journal of molecular biology 20100611
Sex differences in the phosphorylation of mitochondrial proteins result in reduced production of reactive oxygen species and cardioprotection in females. Circulation research 20100611
Identification and functional characterization of a novel mitochondrial carrier for citrate and oxoglutarate in Saccharomyces cerevisiae. The Journal of biological chemistry 20100604
Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells. Cell biology and toxicology 20100601
Tricarboxylic acid cycle activity regulates tomato root growth via effects on secondary cell wall production. Plant physiology 20100601
Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes. Molecular & cellular proteomics : MCP 20100601
Bacterial lifestyle in a deep-sea hydrothermal vent chimney revealed by the genome sequence of the thermophilic bacterium Deferribacter desulfuricans SSM1. DNA research : an international journal for rapid publication of reports on genes and genomes 20100601
Effect of alpha-ketoglutarate and N-acetyl cysteine on cyanide-induced oxidative stress mediated cell death in PC12 cells. Toxicology and industrial health 20100601
Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies. Eukaryotic cell 20100601
Enhanced transforming growth factor-beta signaling and fibrogenesis in ovine fetal skeletal muscle of obese dams at late gestation. American journal of physiology. Endocrinology and metabolism 20100601
The genetics of obesity: FTO leads the way. Trends in genetics : TIG 20100601
Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1. Leukemia 20100601
Characterization of growth and metabolism of the haloalkaliphile Natronomonas pharaonis. PLoS computational biology 20100601
Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism. PLoS neglected tropical diseases 20100601
Constraint-based model of Shewanella oneidensis MR-1 metabolism: a tool for data analysis and hypothesis generation. PLoS computational biology 20100601
Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells. The Journal of biological chemistry 20100528
The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion. The Journal of biological chemistry 20100528
Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly. Journal of molecular biology 20100528
Declining capacity of starving Delftia acidovorans MC1 to degrade phenoxypropionate herbicides correlates with oxidative modification of the initial enzyme. Environmental science & technology 20100515
Analysis of expressed sequence tags from the Huperzia serrata leaf for gene discovery in the areas of secondary metabolite biosynthesis and development regulation. Physiologia plantarum 20100501
Metabonomics study of urine from Sprague-Dawley rats exposed to Huang-yao-zi using (1)H NMR spectroscopy. Journal of pharmaceutical and biomedical analysis 20100501
Enhanced cyclic adenosine monophosphate production by Arthrobacter A302 through rational redistribution of metabolic flux. Bioresource technology 20100501
Practical strategies for suppressing hypoxia-inducible factor activity in cancer therapy. Medical hypotheses 20100501
Genetic changes that increase 5-hydroxymethyl furfural resistance in ethanol-producing Escherichia coli LY180. Biotechnology letters 20100501
Isethionate formation from taurine in Chromohalobacter salexigens: purification of sulfoacetaldehyde reductase. Microbiology (Reading, England) 20100501
Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction. Diabetes 20100501
Proteome of platelets in patients with coronary artery disease. Experimental hematology 20100501
Atlas of rice grain filling-related metabolism under high temperature: joint analysis of metabolome and transcriptome demonstrated inhibition of starch accumulation and induction of amino acid accumulation. Plant & cell physiology 20100501
Enzyme activity profiles during fruit development in tomato cultivars and Solanum pennellii. Plant physiology 20100501
Crystal structures of human FIH-1 in complex with quinol family inhibitors. Molecules and cells 20100501
Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella melitensis antigens. PLoS neglected tropical diseases 20100501
Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria. The Plant cell 20100501
Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. Molecular bioSystems 20100501
Comparative Approach of the de novo Fatty Acid Synthesis (Lipogenesis) between Ruminant and Non Ruminant Mammalian Species: From Biochemical Level to the Main Regulatory Lipogenic Genes. Current genomics 20100501
Complete genome sequence of Sulfurospirillum deleyianum type strain (5175). Standards in genomic sciences 20100430
Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase. Chemistry & biology 20100423
Oxygen activation at mononuclear nonheme iron centers: a superoxo perspective. Inorganic chemistry 20100419
The FHA domain of OdhI interacts with the carboxyterminal 2-oxoglutarate dehydrogenase domain of OdhA in Corynebacterium glutamicum. FEBS letters 20100416
High glucose concentrations attenuate hypoxia-inducible factor-1alpha expression and signaling in non-tumor cells. Experimental cell research 20100415
Alpha-ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain. Brain research 20100409
Structural basis for L-lysine feedback inhibition of homocitrate synthase. The Journal of biological chemistry 20100402
Therapeutic manipulation of the HIF hydroxylases. Antioxidants & redox signaling 20100401
Identification in Agrobacterium tumefaciens of the D-galacturonic acid dehydrogenase gene. Applied microbiology and biotechnology 20100401
Normoxic destabilization of ATF-4 depends on proteasomal degradation. Acta physiologica (Oxford, England) 20100401
Metal and substrate binding to an Fe(II) dioxygenase resolved by UV spectroscopy with global regression analysis. Analytical biochemistry 20100401
Trypanosoma brucei brucei: thymine 7-hydroxylase-like proteins. Experimental parasitology 20100401
Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum. Applied microbiology and biotechnology 20100401
Adipocyte extracellular matrix composition, dynamics and role in obesity. Cellular and molecular life sciences : CMLS 20100401
The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma. Acta neuropathologica 20100401
Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance. Journal of applied physiology (Bethesda, Md. : 1985) 20100401
Simultaneous quantitative determination of alpha-ketoglutaric acid and 5-hydroxymethylfurfural in human plasma by gas chromatography-mass spectrometry. Analytical and bioanalytical chemistry 20100401
Use of response surface methodology in a fed-batch process for optimization of tricarboxylic acid cycle intermediates to achieve high levels of canthaxanthin from Dietzia natronolimnaea HS-1. Journal of bioscience and bioengineering 20100401
Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes. PLoS computational biology 20100401
Purification, crystallization and preliminary X-ray analysis of the aspartate aminotransferase of Plasmodium falciparum. Acta crystallographica. Section F, Structural biology and crystallization communications 20100401
A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito. PLoS neglected tropical diseases 20100401
OptForce: an optimization procedure for identifying all genetic manipulations leading to targeted overproductions. PLoS computational biology 20100401
Up-regulation of the lysyl hydroxylase 2 gene by acetaminophen and isoniazid is modulated by transcription factor c-Myb. The Journal of pharmacy and pharmacology 20100401
The essential toxin: impact of zinc on human health. International journal of environmental research and public health 20100401
Succinylphosphonate esters are competitive inhibitors of MenD that show active-site discrimination between homologous alpha-ketoglutarate-decarboxylating enzymes. Biochemistry 20100330
NMR-based metabonomic study of the sub-acute toxicity of titanium dioxide nanoparticles in rats after oral administration. Nanotechnology 20100326
Metabolism, gliomas, and IDH1. The New England journal of medicine 20100325
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. Cancer cell 20100316
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization. Human molecular genetics 20100315
A 'random steady-state' model for the pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase enzyme complexes. Physical biology 20100312
Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers. The Journal of biological chemistry 20100305
Structural insights into the prereaction state of pyruvate decarboxylase from Zymomonas mobilis . Biochemistry 20100302
Mechanism of S100b release from rat cortical slices determined under basal and stimulated conditions. Neurochemical research 20100301
Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse. Bone 20100301
Oxygen-sensing under the influence of nitric oxide. Cellular signalling 20100301
The protective effects of alpha-ketoacids against oxidative stress on rat spermatozoa in vitro. Asian journal of andrology 20100301
The involvement of lipid peroxide-derived aldehydes in aluminum toxicity of tobacco roots. Plant physiology 20100301
Genomic inventory and transcriptional analysis of Medicago truncatula transporters. Plant physiology 20100301
Identification of circulating placental mRNA in maternal blood of pregnancies affected with fetal congenital heart diseases at the second trimester of pregnancy: implications for early molecular screening. Prenatal diagnosis 20100301
In folio isotopic tracing demonstrates that nitrogen assimilation into glutamate is mostly independent from current CO2 assimilation in illuminated leaves of Brassica napus. The New phytologist 20100301
Reconstruction of metabolic pathways, protein expression, and homeostasis machineries across maize bundle sheath and mesophyll chloroplasts: large-scale quantitative proteomics using the first maize genome assembly. Plant physiology 20100301
Glycolysis and the tricarboxylic acid cycle are linked by alanine aminotransferase during hypoxia induced by waterlogging of Lotus japonicus. Plant physiology 20100301
Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde. Chembiochem : a European journal of chemical biology 20100301
Early hepatic insulin resistance in mice: a metabolomics analysis. Molecular endocrinology (Baltimore, Md.) 20100301
Dual control of cytosolic metals by lysosomal transporters in lobster hepatopancreas. The Journal of experimental biology 20100301
Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response. PLoS biology 20100301
Homeostatic interplay between bacterial cell-cell signaling and iron in virulence. PLoS pathogens 20100301
The essentials of protein import in the degenerate mitochondrion of Entamoeba histolytica. PLoS pathogens 20100301
DFT study of a model system for the dealkylation step catalyzed by AlkB. Interdisciplinary sciences, computational life sciences 20100301
Past, present and future therapeutics for cerebellar ataxias. Current neuropharmacology 20100301
Different experimental approaches in modelling cataractogenesis: An overview of selenite-induced nuclear cataract in rats. Interdisciplinary toxicology 20100301
Complete genome sequence of Desulfohalobium retbaense type strain (HR(100)). Standards in genomic sciences 20100227
Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches. Journal of medicinal chemistry 20100225
Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase. FEBS letters 20100219
Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding. The New England journal of medicine 20100211
Protective roles of Asperosaponin VI, a triterpene saponin isolated from Dipsacus asper Wall on acute myocardial infarction in rats. European journal of pharmacology 20100210
The influence of the acyl chain composition of cardiolipin on the stability of mitochondrial complexes; an unexpected effect of cardiolipin in alpha-ketoglutarate dehydrogenase and prohibitin complexes. Journal of proteomics 20100210
Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from Thermus thermophilus. The Journal of biological chemistry 20100205
Flocculation of dimorphic yeast Benjaminiella poitrasii is altered by modulation of NAD-glutamate dehydrogenase. Bioresource technology 20100201
Expression and molecular characterization of the Mycobacterium tuberculosis PII protein. Journal of biochemistry 20100201
Urinary metabonomic study on biochemical changes in chronic unpredictable mild stress model of depression. Clinica chimica acta; international journal of clinical chemistry 20100201
Glutamine metabolism is essential for human cytomegalovirus infection. Journal of virology 20100201
Alterations in brain glucose utilization accompanying elevations in blood ethanol and acetate concentrations in the rat. Alcoholism, clinical and experimental research 20100201
Downregulation of pyrophosphate: D-fructose-6-phosphate 1-phosphotransferase activity in sugarcane culms enhances sucrose accumulation due to elevated hexose-phosphate levels. Planta 20100201
Energy production genes sucB and ubiF are involved in persister survival and tolerance to multiple antibiotics and stresses in Escherichia coli. FEMS microbiology letters 20100201
Branched-chain and aromatic amino acid catabolism into aroma volatiles in Cucumis melo L. fruit. Journal of experimental botany 20100201
Structural insights into a novel histone demethylase PHF8. Cell research 20100201
Interpreting metabolomic profiles using unbiased pathway models. PLoS computational biology 20100201
Using NMR solvent water relaxation to investigate metalloenzyme-ligand binding interactions. Journal of medicinal chemistry 20100128
Crystal structure of prolyl 4-hydroxylase from Bacillus anthracis. Biochemistry 20100112
Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase. The EMBO journal 20100106
Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites. DNA repair 20100102
Effects of alpha-ketoglutarate on neutrophil intracellular amino and alpha-keto acid profiles and ROS production. Amino acids 20100101
Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. Biochimica et biophysica acta 20100101
SigC sigma factor is involved in acclimation to low inorganic carbon at high temperature in Synechocystis sp. PCC 6803. Microbiology (Reading, England) 20100101
Improving baculovirus production at high cell density through manipulation of energy metabolism. Metabolic engineering 20100101
Short-term effects of zinc on acetylcholine metabolism and viability of SN56 cholinergic neuroblastoma cells. Neurochemistry international 20100101
Molecular cloning of lamprey uncoupling protein and assessment of its uncoupling activity using a yeast heterologous expression system. Mitochondrion 20100101
Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism. The Journal of endocrinology 20100101
Increased chemoresistance induced by inhibition of HIF-prolyl-hydroxylase domain enzymes. Cancer science 20100101
Prevalence of loss-of-function FTO mutations in lean and obese individuals. Diabetes 20100101
The 2-oxoglutarate/malate translocator mediates amino acid and storage protein biosynthesis in pea embryos. The Plant journal : for cell and molecular biology 20100101
Pentanol isomer synthesis in engineered microorganisms. Applied microbiology and biotechnology 20100101
Automatic policing of biochemical annotations using genomic correlations. Nature chemical biology 20100101
A mutation in GDP-mannose pyrophosphorylase causes conditional hypersensitivity to ammonium, resulting in Arabidopsis root growth inhibition, altered ammonium metabolism, and hormone homeostasis. Journal of experimental botany 20100101
Enzymatic and electron paramagnetic resonance studies of anabolic pyruvate synthesis by pyruvate: ferredoxin oxidoreductase from Hydrogenobacter thermophilus. The FEBS journal 20100101
Mild reductions in mitochondrial NAD-dependent isocitrate dehydrogenase activity result in altered nitrate assimilation and pigmentation but do not impact growth. Molecular plant 20100101
Modeling mitochondrial bioenergetics with integrated volume dynamics. PLoS computational biology 20100101
Global transcriptional analysis of nitrogen fixation and ammonium repression in root-associated Pseudomonas stutzeri A1501. BMC genomics 20100101
Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae. BMC biochemistry 20100101
Integrative analysis of the heat shock response in Aspergillus fumigatus. BMC genomics 20100101
Evolution of electron transfer out of the cell: comparative genomics of six Geobacter genomes. BMC genomics 20100101
Proteomic analysis of peach fruit mesocarp softening and chilling injury using difference gel electrophoresis (DIGE). BMC genomics 20100101
Structural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching. PloS one 20100101
Control of ATP homeostasis during the respiro-fermentative transition in yeast. Molecular systems biology 20100101
Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. PloS one 20100101
Detection and manipulation of mitochondrial reactive oxygen species in mammalian cells. Biochimica et biophysica acta 20100101
Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes. BMC genomics 20100101
Metabolic regulation of Escherichia coli and its gdhA, glnL, gltB, D mutants under different carbon and nitrogen limitations in the continuous culture. Microbial cell factories 20100101
Placental gene expression is related to glucose metabolism and fetal cord blood levels of insulin and insulin-like growth factors in intrauterine growth restriction. Early human development 20100101
Rapid determination of tricarboxylic acid cycle enzyme activities in biological samples. BMC biochemistry 20100101
The Arabidopsis pop2-1 mutant reveals the involvement of GABA transaminase in salt stress tolerance. BMC plant biology 20100101
In silico feasibility of novel biodegradation pathways for 1,2,4-trichlorobenzene. BMC systems biology 20100101
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing. PloS one 20100101
The regulation of OXPHOS by extramitochondrial calcium. Biochimica et biophysica acta 20100101
Overexpression of bacterial ethylene-forming enzyme gene in Trichoderma reesei enhanced the production of ethylene. International journal of biological sciences 20100101
Transcriptional regulation of respiration in yeast metabolizing differently repressive carbon substrates. BMC systems biology 20100101
Structural and functional restraints on the occurrence of single amino acid variations in human proteins. PloS one 20100101
Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue. BMC genomics 20100101
Neonatal maternal deprivation response and developmental changes in gene expression revealed by hypothalamic gene expression profiling in mice. PloS one 20100101
Entamoeba histolytica Phosphoserine aminotransferase (EhPSAT): insights into the structure-function relationship. BMC research notes 20100101
Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs. PloS one 20100101
Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome. BMC genomics 20100101
Effects of carboxylic acids on the uptake of non-transferrin-bound iron by astrocytes. Neurochemistry international 20100101
Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. PloS one 20100101
Immunoproteomics analysis of the murine antibody response to vaccination with an improved Francisella tularensis live vaccine strain (LVS). PloS one 20100101
Genetic analysis of central carbon metabolism unveils an amino acid substitution that alters maize NAD-dependent isocitrate dehydrogenase activity. PloS one 20100101
Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages. BMC microbiology 20100101
The unique kinetic behavior of the very large NAD-dependent glutamate dehydrogenase from Janthinobacterium lividum. Bioscience, biotechnology, and biochemistry 20100101
The creation and physiological relevance of divergent hydroxylation patterns in the flavonoid pathway. International journal of molecular sciences 20100101
Co-expression of Skp and FkpA chaperones improves cell viability and alters the global expression of stress response genes during scFvD1.3 production. Microbial cell factories 20100101
Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes. PloS one 20100101
Metabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology. Journal of biomedicine & biotechnology 20100101
Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin inhibits the proliferation of ARPE-19 cells. Journal of biomedical science 20100101
Dynamics and control of the central carbon metabolism in hepatoma cells. BMC systems biology 20100101
Cancer genomics identifies determinants of tumor biology. Genome biology 20100101
The expression and significance of IDH1 and p53 in osteosarcoma. Journal of experimental & clinical cancer research : CR 20100101
Glutamate dehydrogenase and glutamine synthetase are regulated in response to nitrogen availability in Myocbacterium smegmatis. BMC microbiology 20100101
Metabolomic and transcriptomic stress response of Escherichia coli. Molecular systems biology 20100101
The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments. PloS one 20100101
The human collagen beta(1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum localized protein. BMC cell biology 20100101
Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis. BMC systems biology 20100101
Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes. PloS one 20100101
Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. International journal of molecular sciences 20100101
Proteomics reveals a core molecular response of Pseudomonas putida F1 to acute chromate challenge. BMC genomics 20100101
Carbon metabolism of enterobacterial human pathogens growing in epithelial colorectal adenocarcinoma (Caco-2) cells. PloS one 20100101
The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo. BMC medicine 20100101
Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron(II) and 2-oxoglutarate-dependent dioxygenase EctD. PloS one 20100101
Transcriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii. BMC genomics 20100101
Proteomic Profiling of the Dystrophin-Deficient MDX Heart Reveals Drastically Altered Levels of Key Metabolic and Contractile Proteins. Journal of biomedicine & biotechnology 20100101
Transcriptional control by two leucine-responsive regulatory proteins in Halobacterium salinarum R1. BMC molecular biology 20100101
Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. Molecular cancer 20100101
Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate. BMC genomics 20100101
The network of P(II) signalling protein interactions in unicellular cyanobacteria. Advances in experimental medicine and biology 20100101
Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss. PloS one 20100101
Selective neuronal vulnerability to oxidative stress in the brain. Frontiers in aging neuroscience 20100101
Halogenated indole alkaloids from marine invertebrates. Marine drugs 20100101
Structural and transcriptional analysis of plant genes encoding the bifunctional lysine ketoglutarate reductase saccharopine dehydrogenase enzyme. BMC plant biology 20100101
Water buffalo genome science comes of age. International journal of biological sciences 20100101
Inborn errors of energy metabolism associated with myopathies. Journal of biomedicine & biotechnology 20100101
A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients. Molecular cancer 20100101
The complete genome sequence of the pathogenic intestinal spirochete Brachyspira pilosicoli and comparison with other Brachyspira genomes. PloS one 20100101
Divergence involving global regulatory gene mutations in an Escherichia coli population evolving under phosphate limitation. Genome biology and evolution 20100101
Compartmentalization of the Edinburgh Human Metabolic Network. BMC bioinformatics 20100101
Proteomic analysis of growth phase-dependent expression of Legionella pneumophila proteins which involves regulation of bacterial virulence traits. PloS one 20100101
Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90. PloS one 20100101
Specificity of the acute tryptophan and tyrosine plus phenylalanine depletion and loading tests I. Review of biochemical aspects and poor specificity of current amino Acid formulations. International journal of tryptophan research : IJTR 20100101
A global metabolic shift is linked to Salmonella multicellular development. PloS one 20100101
Predicted class-I aminoacyl tRNA synthetase-like proteins in non-ribosomal peptide synthesis. Biology direct 20100101
Modulation of redox homeostasis under suboptimal conditions by Arabidopsis nudix hydrolase 7. BMC plant biology 20100101
Integration of metabolic databases for the reconstruction of genome-scale metabolic networks. BMC systems biology 20100101
Nitric oxide: perspectives and emerging studies of a well known cytotoxin. International journal of molecular sciences 20100101
Integrative inference of gene-regulatory networks in Escherichia coli using information theoretic concepts and sequence analysis. BMC systems biology 20100101
Specificity of the Acute Tryptophan and Tyrosine Plus Phenylalanine Depletion and Loading Tests Part II: Normalisation of the Tryptophan and the Tyrosine Plus Phenylalanine to Competing Amino Acid Ratios in a New Control Formulation. International journal of tryptophan research : IJTR 20100101
Comparative effects of selected non-caffeinated rehydration sports drinks on short-term performance following moderate dehydration. Journal of the International Society of Sports Nutrition 20100101
Oxidant-NO dependent gene regulation in dogs with type I diabetes: impact on cardiac function and metabolism. Cardiovascular diabetology 20100101
Identification of transcriptome induced in roots of maize seedlings at the late stage of waterlogging. BMC plant biology 20100101
Oral microencapsulated live Saccharomyces cerevisiae cells for use in renal failure uremia: preparation and in vivo analysis. Journal of biomedicine & biotechnology 20100101
Recent advances in the treatment of acute myeloid leukemia. F1000 medicine reports 20100101
Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis. Critical care (London, England) 20100101
Gut microbial gene expression in mother-fed and formula-fed piglets. PloS one 20100101
A systematic investigation of Escherichia coli central carbon metabolism in response to superoxide stress. BMC systems biology 20100101
Oxygen sensing in Drosophila: multiple isoforms of the prolyl hydroxylase fatiga have different capacity to regulate HIFalpha/Sima. PloS one 20100101
Prevalence of primary biliary cirrhosis in adults referring hospital for annual health check-up in Southern China. BMC gastroenterology 20100101
Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network. Molecular systems biology 20100101
Comparative genomic analysis of pathogenic and probiotic Enterococcus faecalis isolates, and their transcriptional responses to growth in human urine. PloS one 20100101
Transcriptional profile of maize roots under acid soil growth. BMC plant biology 20100101
The genome of Geobacter bemidjiensis, exemplar for the subsurface clade of Geobacter species that predominate in Fe(III)-reducing subsurface environments. BMC genomics 20100101
Membrane proteomic analysis of pancreatic cancer cells. Journal of biomedical science 20100101
Mitochondrial preconditioning: a potential neuroprotective strategy. Frontiers in aging neuroscience 20100101
The evolutionary trajectory of mitochondrial carrier family during metazoan evolution. BMC evolutionary biology 20100101
Functional characterization of the incomplete phosphotransferase system (PTS) of the intracellular pathogen Brucella melitensis. PloS one 20100101
Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update. Clinical interventions in aging 20100101
Sex-different hepaticglycogen content and glucose output in rats. BMC biochemistry 20100101
Complete genome and comparative analysis of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5. BMC genomics 20100101
Understanding the physiology of Lactobacillus plantarum at zero growth. Molecular systems biology 20100101
[Oxidative damage of mitochondrial DNA: the result or consequence of enhanced generation of reactive oxygen species]. Postepy biochemii 20100101
[The new face of factors induced by hypoxia--HIF-1 and HIF-2 and oxidative stress]. Postepy biochemii 20100101
Iron-sulfur world in aerobic and hyperthermoacidophilic archaea Sulfolobus. Archaea (Vancouver, B.C.) 20100101
Elementary mode analysis for the rational design of efficient succinate conversion from glycerol by Escherichia coli. Journal of biomedicine & biotechnology 20100101
MetAssimulo: simulation of realistic NMR metabolic profiles. BMC bioinformatics 20100101
Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence. BMC genomics 20100101
Response of swine spleen to Streptococcus suis infection revealed by transcription analysis. BMC genomics 20100101
Protective efficacy of natansnin, a dibenzoyl glycoside from Salvinia natans against CCl4 induced oxidative stress and cellular degeneration in rat liver. BMC pharmacology 20100101
Impact of ocean acidification on energy metabolism of oyster, Crassostrea gigas--changes in metabolic pathways and thermal response. Marine drugs 20100101
Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice. PPAR research 20100101
Toxicometabolomics of urinary biomarkers for human gastric cancer in a mouse model. Journal of toxicology and environmental health. Part A 20100101
Deciphering the intracellular metabolism of Listeria monocytogenes by mutant screening and modelling. BMC genomics 20100101
cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. PloS one 20100101
Quantitative analysis of cellular metabolic dissipative, self-organized structures. International journal of molecular sciences 20100101
The aconitate hydratase family from Citrus. BMC plant biology 20100101
Physiological relation between respiration activity and heterologous expression of selected benzoylformate decarboxylase variants in Escherichia coli. Microbial cell factories 20100101
A multi-level study of recombinant Pichia pastoris in different oxygen conditions. BMC systems biology 20100101
Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major. Journal of nucleic acids 20100101
Protective effects of combination of quercetin and α-tocopherol on mitochondrial dysfunction and myocardial infarct size in isoproterenol-treated myocardial infarcted rats: biochemical, transmission electron microscopic, and macroscopic enzyme mapping evidences. Journal of biochemical and molecular toxicology 20100101
Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems. Journal of nucleic acids 20100101
A metabonomic comparison of urinary changes in Zucker and GK rats. Journal of biomedicine & biotechnology 20100101
Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. International journal of Alzheimer's disease 20100101
Review of factors affecting the growth and survival of follicular grafts. Journal of cutaneous and aesthetic surgery 20100101
Short- and long-term consequences on biochemical markers after fundectomy in pigs supplemented with 3-hydroxy-3-methylbutyrate and alpha-ketoglutarate. Berliner und Munchener tierarztliche Wochenschrift 20100101
Mitochondrial metabolites in tissues as indicators of metabolic alterations during hibernation. Cryo letters 20100101
Some nutritional, technological and environmental advances in the use of enzymes in meat products. Enzyme research 20100101
Behavioral impact of the regulation of the brain 2-oxoglutarate dehydrogenase complex by synthetic phosphonate analog of 2-oxoglutarate: implications into the role of the complex in neurodegenerative diseases. International journal of Alzheimer's disease 20100101
Thiamine status in humans and content of phosphorylated thiamine derivatives in biopsies and cultured cells. PloS one 20100101
Intra- and extra-cellular flux distributions of TCA and glyoxalate cycle and vancomycin production of Amycolatopsis orieantalis grown in different glycerol concentration. Prikladnaia biokhimiia i mikrobiologiia 20100101
Analysis of Jmjd6 cellular localization and testing for its involvement in histone demethylation. PloS one 20100101
Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects. PloS one 20100101
An incomplete TCA cycle increases survival of Salmonella Typhimurium during infection of resting and activated murine macrophages. PloS one 20100101
Reconstruction and analysis of genome-scale metabolic model of a photosynthetic bacterium. BMC systems biology 20100101
Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling. PloS one 20100101
Metabolic response of Geobacter sulfurreducens towards electron donor/acceptor variation. Microbial cell factories 20100101
The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies. Microbial cell factories 20100101
An empirical strategy for characterizing bacterial proteomes across species in the absence of genomic sequences. PloS one 20100101
The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. PloS one 20100101
Differential proteomic analysis highlights metabolic strategies associated with balhimycin production in Amycolatopsis balhimycina chemostat cultivations. Microbial cell factories 20100101
ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics. Molecular neurodegeneration 20100101
DNA damage induced by alkylating agents and repair pathways. Journal of nucleic acids 20100101
Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast. Molecular systems biology 20100101
Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. PloS one 20100101
Interaction with diurnal and circadian regulation results in dynamic metabolic and transcriptional changes during cold acclimation in Arabidopsis. PloS one 20100101
Effect of gadolinium chloride on liver regeneration following thioacetamide-induced necrosis in rats. International journal of molecular sciences 20100101
The Lrp family of transcription regulators in archaea. Archaea (Vancouver, B.C.) 20100101
Protein markers for insulin-producing beta cells with higher glucose sensitivity. PloS one 20100101
Transcriptional analysis implicates endoplasmic reticulum stress in bovine spongiform encephalopathy. PloS one 20100101
Biliary epithelial apoptosis, autophagy, and senescence in primary biliary cirrhosis. Hepatitis research and treatment 20100101
Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. PloS one 20100101
Analysis of candidate genes for macular telangiectasia type 2. Molecular vision 20100101
Identification and Partial Characterization of an L-Tyrosine Aminotransferase (TAT) from Arabidopsis thaliana. Biochemistry research international 20100101
The genome sequence of Methanohalophilus mahii SLP(T) reveals differences in the energy metabolism among members of the Methanosarcinaceae inhabiting freshwater and saline environments. Archaea (Vancouver, B.C.) 20100101
The effect of AmtR on growth and amino acids production in Corynebacterium glutamicum. Prikladnaia biokhimiia i mikrobiologiia 20100101
Hot transcriptomics. Archaea (Vancouver, B.C.) 20100101
[Hepatotoxic efects of acetaminophen. Protective properties of tryptophan-derivatives]. Biomeditsinskaia khimiia 20100101
Biochemistry and occurrence of o-demethylation in plant metabolism. Frontiers in physiology 20100101
The role of mitochondria for the regulation of cardiac alternans. Frontiers in physiology 20100101
Role of the mitochondrion in programmed necrosis. Frontiers in physiology 20100101
Amelioration of lead-induced hepatotoxicity by Allium sativum extracts in Swiss albino mice. The Libyan journal of medicine 20100101
Wernicke's Encephalopathy in Colon Cancer. Case reports in oncology 20100101
Biochemical and histologic changes in rats after prolonged administration of the crude aqueous extract of the leaves of Vitex grandifolia. Pharmacognosy research 20100101
AMPylation: Something Old is New Again. Frontiers in microbiology 20100101
Isolation and characterization of genes functionally involved in ovarian development of the giant tiger shrimp Penaeus monodon by suppression subtractive hybridization (SSH). Genetics and molecular biology 20100101
Alterations in gene expression profiles correlated with cisplatin cytotoxicity in the glioma U343 cell line. Genetics and molecular biology 20100101
The francisella tularensis proteome and its recognition by antibodies. Frontiers in microbiology 20100101
Possible implication of oxidative stress in anti filarial effect of certain traditionally used medicinal plants in vitro against Brugia malayi microfilariae. Pharmacognosy research 20100101
Animal models of Alzheimer's disease. International journal of Alzheimer's disease 20100101
Chemical warfare agents. Journal of pharmacy & bioallied sciences 20100101
A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli. Advances and applications in bioinformatics and chemistry : AABC 20100101
Role of Mitochondrial Enzymes and Sarcoplasmic ATPase in Cardioprotection Mediated by Aqueous Extract of Desmodium gangeticum (L) DC Root on Ischemic Reperfusion Injury. Indian journal of pharmaceutical sciences 20100101
Electrochemical microsensors for the detection of cadmium(II) and lead(II) ions in plants. Sensors (Basel, Switzerland) 20100101
Congenital hyperinsulinism with hyperammonaemia. BMJ case reports 20100101
Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. The Journal of biological chemistry 20091218
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Metabolomic analysis of biofluids from rats treated with Aconitum alkaloids using nuclear magnetic resonance and gas chromatography/time-of-flight mass spectrometry. Analytical biochemistry 20091215
Small RNA-dependent expression of secondary metabolism is controlled by Krebs cycle function in Pseudomonas fluorescens. The Journal of biological chemistry 20091211
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Sensation and signaling of alpha-ketoglutarate and adenylylate energy charge by the Escherichia coli PII signal transduction protein require cooperation of the three ligand-binding sites within the PII trimer. Biochemistry 20091208
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A novel role for fatty acid transport protein 1 in the regulation of tricarboxylic acid cycle and mitochondrial function in 3T3-L1 adipocytes. Journal of lipid research 20091201
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Development and implementation of a novel assay for L-2-hydroxyglutarate dehydrogenase (L-2-HGDH) in cell lysates: L-2-HGDH deficiency in 15 patients with L-2-hydroxyglutaric aciduria. Journal of inherited metabolic disease 20091201
Organ preservation solutions attenuate accumulation and nuclear translocation of hypoxia-inducible factor-1alpha in the hepatoma cell line HepG2. Cell biochemistry and function 20091201
Functional characterization of a Na(+)-coupled dicarboxylate transporter from Bacillus licheniformis. Biochimica et biophysica acta 20091201
Analysis of time course 1H NMR metabolomics data by multivariate curve resolution. Magnetic resonance in chemistry : MRC 20091201
Cloning, expression, and enzymatic characterization of isocitrate dehydrogenase from Helicobacter pylori. The protein journal 20091201
Analysis of the intermediary metabolism of a reductive chemoautotroph. The Biological bulletin 20091201
The Bifidobacterium dentium Bd1 genome sequence reflects its genetic adaptation to the human oral cavity. PLoS genetics 20091201
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Regulation of mitochondrial dehydrogenases by calcium ions. Biochimica et biophysica acta 20091101
Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. Journal of biochemistry 20091101
A continuous microplate assay for sirtuins and nicotinamide-producing enzymes. Analytical biochemistry 20091101
Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins. Neurobiology of disease 20091101
Adsorption mechanism of Cu2+ from aqueous solution by chitosan-coated magnetic nanoparticles modified with alpha-ketoglutaric acid. Colloids and surfaces. B, Biointerfaces 20091101
Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing. Cellular and molecular life sciences : CMLS 20091101
Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus. Molecular microbiology 20091101
2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2. Bioorganic & medicinal chemistry letters 20091101
Genetic and biochemical analysis of the serine/threonine protein kinases PknA, PknB, PknG and PknL of Corynebacterium glutamicum: evidence for non-essentiality and for phosphorylation of OdhI and FtsZ by multiple kinases. Molecular microbiology 20091101
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Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica. PLoS genetics 20091101
Histidine-tryptophan-ketoglutarate and delayed graft function after prolonged cold ischemia. Transplantation proceedings 20091101
An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis. PLoS pathogens 20091101
Prebiotic metabolism: production by mineral photoelectrochemistry of alpha-ketocarboxylic acids in the reductive tricarboxylic acid cycle. Astrobiology 20091101
Structural and functional analysis of Vitamin K2 synthesis protein MenD. Biochemical and biophysical research communications 20091030
First-principles study of non-heme Fe(II) halogenase SyrB2 reactivity. Journal of the American Chemical Society 20091014
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D-xylose degradation pathway in the halophilic archaeon Haloferax volcanii. The Journal of biological chemistry 20091002
Metabolite regulation of the interaction between Arabidopsis thaliana PII and N-acetyl-l-glutamate kinase. Biochemical and biophysical research communications 20091002
Enhanced production of poly (gamma-glutamic acid) from Bacillus licheniformis NCIM 2324 by using metabolic precursors. Applied biochemistry and biotechnology 20091001
Ganoderma lucidum (Fr.) P. Karst enhances activities of heart mitochondrial enzymes and respiratory chain complexes in the aged rat. Biogerontology 20091001
Preservation of the in vivo state of mitochondrial network for ex vivo physiological study of mitochondria. The international journal of biochemistry & cell biology 20091001
Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease. Neurotoxicity research 20091001
Colloidal nanoparticles as a wireless booster for electroenzymatic reactions. Small (Weinheim an der Bergstrasse, Germany) 20091001
Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20091001
Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition. Free radical biology & medicine 20091001
Aspergillus terreus NADP-glutamate dehydrogenase is kinetically distinct from the allosteric enzyme of other Aspergilli. Mycological research 20091001
Direct effects of corticosterone on ATP production by mitochondria from immortalized hypothalamic GT1-7 neurons. The Journal of steroid biochemistry and molecular biology 20091001
The Pitx2c N-terminal domain is a critical interaction domain required for asymmetric morphogenesis. Developmental dynamics : an official publication of the American Association of Anatomists 20091001
Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency. Journal of neurochemistry 20091001
Resolving the role of plant glutamate dehydrogenase. I. In vivo real time nuclear magnetic resonance spectroscopy experiments. Plant & cell physiology 20091001
Neuronal apoptosis by prolyl hydroxylation: implication in nervous system tumours and the Warburg conundrum. Journal of cellular and molecular medicine 20091001
Glutamate metabolic pathways and retinal function. Journal of neurochemistry 20091001
Role of plant glyoxylate reductases during stress: a hypothesis. The Biochemical journal 20091001
Structure-based predictive models for allosteric hot spots. PLoS computational biology 20091001
Chemical and functional aspects of posttranslational modification of proteins. Acta naturae 20091001
Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats. Brain research 20090929
Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981 type strain JR1. Standards in genomic sciences 20090929
Complete genome sequence of Methanocorpusculum labreanum type strain Z. Standards in genomic sciences 20090929
Production of bioactive, post-translationally modified, heterotrimeric, human recombinant type-I collagen in transgenic tobacco. Biomacromolecules 20090914
The crystal structure of an algal prolyl 4-hydroxylase complexed with a proline-rich peptide reveals a novel buried tripeptide binding motif. The Journal of biological chemistry 20090911
SDH5 mutations and familial paraganglioma: somewhere Warburg is smiling. Cancer cell 20090908
Acute toxicity of some synthetic cyanogens in rats and their response to oral treatment with alpha-ketoglutarate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090901
Antitumor effects of 2-oxoglutarate through inhibition of angiogenesis in a murine tumor model. Cancer science 20090901
Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination. Biochimie 20090901
Primary biliary cirrhosis. Seminars in immunopathology 20090901
Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090901
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus. Nature chemical biology 20090901
Metabolic discrimination of Catharanthus roseus calli according to their relative locations using (1)H-NMR and principal component analysis. Bioscience, biotechnology, and biochemistry 20090901
[Metabonomic study on the effects of allicin on rats]. Yao xue xue bao = Acta pharmaceutica Sinica 20090901
Lipoic acid synthesis and attachment in yeast mitochondria. The Journal of biological chemistry 20090828
Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation. The Biochemical journal 20090827
Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. The Journal of biological chemistry 20090821
Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38. The Journal of biological chemistry 20090821
Assay and purification of omega-amidase/Nit2, a ubiquitously expressed putative tumor suppressor, that catalyzes the deamidation of the alpha-keto acid analogues of glutamine and asparagine. Analytical biochemistry 20090815
Proline oxidase functions as a mitochondrial tumor suppressor in human cancers. Cancer research 20090815
Flexible heteroarotinoid (Flex-Het) SHetA2 inhibits angiogenesis in vitro and in vivo. Investigational new drugs 20090801
Differential effects of bone morphogenetic protein-2 and transforming growth factor-beta1 on gene expression of collagen-modifying enzymes in human adipose tissue-derived mesenchymal stem cells. Tissue engineering. Part A 20090801
Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study. Molecular and cellular biochemistry 20090801
Central metabolism in Mycobacterium smegmatis during the transition from O2-rich to O2-poor conditions as studied by isotopomer-assisted metabolite analysis. Biotechnology letters 20090801
Functional characterization of stage-specific aminotransferases from trypanosomatids. Molecular and biochemical parasitology 20090801
Chemoorganoheterotrophic growth of Nitrosomonas europaea and Nitrosomonas eutropha. Current microbiology 20090801
Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors. Journal of neuro-oncology 20090801
Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801
Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis. Biochimie 20090801
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. Nature chemical biology 20090801
Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme. Bioorganic & medicinal chemistry 20090801
Efficacy and safety of ornithine alpha-ketoglutarate in heel pressure ulcers in elderly patients: results of a randomized controlled trial. The journal of nutrition, health & aging 20090801
Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice. Genes to cells : devoted to molecular & cellular mechanisms 20090801
Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm. Radiation research 20090801
Drilling for energy in mitochondrial disease. Archives of neurology 20090801
Human NARP mitochondrial mutation metabolism corrected with alpha-ketoglutarate/aspartate: a potential new therapy. Archives of neurology 20090801
[Nephrotoxicity study of Aristolochia fangchi in rats by metabonomics]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20090801
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. PLoS genetics 20090801
On the accessibility of adaptive phenotypes of a bacterial metabolic network. PLoS computational biology 20090801
Modifying the alkylglucosinolate profile in Arabidopsis thaliana alters the tritrophic interaction with the herbivore Brevicoryne brassicae and parasitoid Diaeretiella rapae. Journal of chemical ecology 20090801
Phosphono analogues of 2-oxoglutarate protect cerebellar granule neurons upon glutamate excitotoxicity. Annals of the New York Academy of Sciences 20090801
Integrative normalization and comparative analysis for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. Analytical chemistry 20090715
Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases. Structure (London, England : 1993) 20090715
Origin of the correlation of the rate constant of substrate hydroxylation by nonheme iron(IV)-oxo complexes with the bond-dissociation energy of the C-H bond of the substrate. Chemistry (Weinheim an der Bergstrasse, Germany) 20090706
Chemically assisted microbial production of succinic acid by the yeast Yarrowia lipolytica grown on ethanol. Applied microbiology and biotechnology 20090701
Metabonomic identification of novel biomarkers in doxorubicin cardiotoxicity and protective effect of the natural antioxidant oleuropein. NMR in biomedicine 20090701
The role of respiratory donor enzymes in Campylobacter jejuni host colonization and physiology. Microbial pathogenesis 20090701
A functional analysis of the pyrimidine catabolic pathway in Arabidopsis. The New phytologist 20090701
Regulation and function of proline oxidase under nutrient stress. Journal of cellular biochemistry 20090701
A redox-mediated modulation of stem bolting in transgenic Nicotiana sylvestris differentially expressing the external mitochondrial NADPH dehydrogenase. Plant physiology 20090701
Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate. Journal of experimental botany 20090701
Analysis of achromobactin biosynthesis by Pseudomonas syringae pv. syringae B728a. Journal of bacteriology 20090701
Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response. Journal of proteome research 20090701
Characterization of a robust enzymatic assay for inhibitors of 2-oxoglutarate-dependent hydroxylases. Journal of biomolecular screening 20090701
Metabonomic study of ochratoxin a toxicity in rats after repeated administration: phenotypic anchoring enhances the ability for biomarker discovery. Chemical research in toxicology 20090701
Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts. PLoS computational biology 20090701
Linkage between circadian clock and tricarboxylic acid cycle in Arabidopsis. Plant signaling & behavior 20090701
Protective role of alpha-ketoglutarate against massive doses of cyanide in rats. Journal of environmental biology 20090701
Biochemical characterization of the prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B complex. The Journal of biological chemistry 20090626
N-acetyl-L-glutamate kinase (NAGK) from oxygenic phototrophs: P(II) signal transduction across domains of life reveals novel insights in NAGK control. Journal of molecular biology 20090619
A game with many players: control of gdh transcription in Corynebacterium glutamicum. Journal of biotechnology 20090615
Use of an osmium complex as a universal luminescent probe for enzymatic reactions. Chemistry (Weinheim an der Bergstrasse, Germany) 20090615
TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2. The Journal of investigative dermatology 20090601
Effects of indole-3-acetic acid on Sinorhizobium meliloti survival and on symbiotic nitrogen fixation and stem dry weight production. Applied microbiology and biotechnology 20090601
From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Microbiology (Reading, England) 20090601
Determination of phosphorylation sites for NADP-specific isocitrate dehydrogenase from mycobacterium tuberculosis. Journal of biomolecular structure & dynamics 20090601
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. Cell cycle (Georgetown, Tex.) 20090601
Bruck syndrome: osteogenesis imperfecta and arthrogryposis multiplex congenita. Annals of tropical paediatrics 20090601
Substrate-triggered formation and remarkable stability of the C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2. Biochemistry 20090526
The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer. British journal of cancer 20090519
A stable and selective electrochemical biosensor for the liver enzyme alanine aminotransferase (ALT). Biosensors & bioelectronics 20090515
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science (New York, N.Y.) 20090515
Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure. Journal of medicinal chemistry 20090514
Aluminum-induced defective mitochondrial metabolism perturbs cytoskeletal dynamics in human astrocytoma cells. Journal of neuroscience research 20090501
Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype. International journal of cancer 20090501
Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free radical biology & medicine 20090501
Directed evolution and rational approaches to improving Streptomyces clavuligerus deacetoxycephalosporin C synthase for cephalosporin production. Journal of industrial microbiology & biotechnology 20090501
Catabolism of nutritionally essential amino acids in developing porcine enterocytes. Amino acids 20090501
Phosphate accumulation of Acetobacter xylinum. Archives of microbiology 20090501
Cloning and characterization of Rhodotorula glutinis thymine hydroxylase. Chemical research in toxicology 20090501
Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan. Experimental gerontology 20090501
Mild reduction in the activity of the alpha-ketoglutarate dehydrogenase complex elevates GABA shunt and glycolysis. Journal of neurochemistry 20090501
Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid. Journal of neurochemistry 20090501
Protective effects of compound FLZ, a novel synthetic analogue of squamosamide, on beta-amyloid-induced rat brain mitochondrial dysfunction in vitro. Acta pharmacologica Sinica 20090501
Synthetic regulators of the 2-oxoglutarate oxidative decarboxylation alleviate the glutamate excitotoxicity in cerebellar granule neurons. Biochemical pharmacology 20090501
Multiple osteoporosis susceptibility genes on chromosome 1p36 in Chinese. Bone 20090501
Biosensor based on glutamate dehydrogenase immobilized in chitosan for the determination of ammonium in water samples. Analytical biochemistry 20090501
Mitochondria and energetic depression in cell pathophysiology. International journal of molecular sciences 20090501
A non-heme iron-mediated chemical demethylation in DNA and RNA. Accounts of chemical research 20090421
Branched-chain 2-oxoacid transamination increases GABA-shunt metabolism and insulin secretion in isolated islets. The Biochemical journal 20090415
Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism. Structure (London, England : 1993) 20090415
Cancer. Puzzling patterns of predisposition. Science (New York, N.Y.) 20090410
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. Science (New York, N.Y.) 20090410
Structural analysis of an open active site conformation of nonheme iron halogenase CytC3. Journal of the American Chemical Society 20090408
L: -2-Hydroxyglutaric aciduria, a disorder of metabolite repair. Journal of inherited metabolic disease 20090401
Neuronal mitochondrial toxicity of malondialdehyde: inhibitory effects on respiratory function and enzyme activities in rat brain mitochondria. Neurochemical research 20090401
2007 annual progress report synopsis of the Center for Structures of Membrane Proteins. Journal of structural and functional genomics 20090401
Fast isotopic exchange between mitochondria and cytosol in brain revealed by relayed 13C magnetization transfer spectroscopy. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090401
Development of a defined medium for Clostridium scatologenes ATCC 25775. Letters in applied microbiology 20090401
Differential expression of a virulence factor in pathogenic and non-pathogenic mycobacteria. Molecular microbiology 20090401
Triggering and amplification of insulin secretion by dimethyl alpha-ketoglutarate, a membrane permeable alpha-ketoglutarate analogue. European journal of pharmacology 20090401
Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate. Journal of experimental botany 20090401
Measurement of D: -2-hydroxyglutarate dehydrogenase activity in cell homogenates derived from D: -2-hydroxyglutaric aciduria patients. Journal of inherited metabolic disease 20090401
Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease. Brain : a journal of neurology 20090401
Novel human pathological mutations. Gene symbol: PLOD1. Disease: Ehlers-Danlos syndrome type VIA, kyphoscoliotic type. Human genetics 20090401
Alpha-ketoglutarate protects the liver of piglets exposed during prenatal life to chronic excess of dexamethasone from metabolic and structural changes. Journal of animal physiology and animal nutrition 20090401
Prophylaxis with alpha-lipoic acid against lipopolysaccharide-induced brain injury in rats. Archivum immunologiae et therapiae experimentalis 20090401
Over-expression of a tomato N-acetyl-L-glutamate synthase gene (SlNAGS1) in Arabidopsis thaliana results in high ornithine levels and increased tolerance in salt and drought stresses. Journal of experimental botany 20090401
A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans. PLoS genetics 20090401
Mapping gene associations in human mitochondria using clinical disease phenotypes. PLoS computational biology 20090401
Intra-mitochondrial poly(ADP-ribosyl)ation: potential role for alpha-ketoglutarate dehydrogenase. Mitochondrion 20090401
Control and regulation of integrated mitochondrial function in metabolic and transport networks. International journal of molecular sciences 20090401
Bidirectionality and compartmentation of metabolic fluxes are revealed in the dynamics of isotopomer networks. International journal of molecular sciences 20090401
Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing. International journal of molecular sciences 20090401
Application of 1H NMR-based metabonomics in the study of metabolic profiling of human hepatocellular carcinoma and liver cirrhosis. Cancer science 20090401
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. The Journal of biological chemistry 20090327
Structural insights of the MenD from Escherichia coli reveal ThDP affinity. Biochemical and biophysical research communications 20090320
Direct and continuous assay for prolyl 4-hydroxylase. Analytical biochemistry 20090315
Manganese (II) induces chemical hypoxia by inhibiting HIF-prolyl hydroxylase: implication in manganese-induced pulmonary inflammation. Toxicology and applied pharmacology 20090315
Calcium signaling in brain mitochondria: interplay of malate aspartate NADH shuttle and calcium uniporter/mitochondrial dehydrogenase pathways. The Journal of biological chemistry 20090313
In vitro interactions between the PII proteins and the nitrogenase regulatory enzymes dinitrogenase reductase ADP-ribosyltransferase (DraT) and dinitrogenase reductase-activating glycohydrolase (DraG) in Azospirillum brasilense. The Journal of biological chemistry 20090313
Oxidative stress mediated cytotoxicity of cyanide in LLC-MK2 cells and its attenuation by alpha-ketoglutarate and N-acetyl cysteine. Toxicology letters 20090310
The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability. Journal of cellular and molecular medicine 20090301
Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins. Molecular & cellular proteomics : MCP 20090301
Alpha-ketoglutarate abrogates the nuclear localization of HIF-1alpha in aluminum-exposed hepatocytes. Biochimie 20090301
Effect of Ganoderma lucidum on the activities of mitochondrial dehydrogenases and complex I and II of electron transport chain in the brain of aged rats. Experimental gerontology 20090301
Thiamine deficiency-related brain dysfunction in chronic liver failure. Metabolic brain disease 20090301
AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. Nature chemical biology 20090301
Arginine kinase from Litopenaeus vannamei: cloning, expression and catalytic properties. Fish & shellfish immunology 20090301
Philosophical basis and some historical aspects of systems biology: from Hegel to Noble - applications for bioenergetic research. International journal of molecular sciences 20090301
On-chip microfluidic systems for determination of L-glutamate based on enzymatic recycling of substrate. Biomicrofluidics 20090301
Characterization of novel 2-oxoglutarate dependent dioxygenases converting L-proline to cis-4-hydroxy-l-proline. Biochemical and biophysical research communications 20090220
Oxaloacetate restores the long-term potentiation impaired in rat hippocampus CA1 region by 2-vessel occlusion. European journal of pharmacology 20090214
Bone mineral density and bone turnover in relation to serum leptin, alpha-ketoglutarate and sex steroids in overweight and obese postmenopausal women. Clinical endocrinology 20090201
Toxicity of select organic acids to the slightly thermophilic acidophile Acidithiobacillus caldus. Environmental toxicology and chemistry 20090201
Dynamic protein methylation in chromatin biology. Cellular and molecular life sciences : CMLS 20090201
Removal of Cu2+ from aqueous solution by chitosan-coated magnetic nanoparticles modified with alpha-ketoglutaric acid. Journal of colloid and interface science 20090201
Iron- and 2-oxoglutarate-dependent dioxygenases: an emerging group of molecular targets for nickel toxicity and carcinogenicity. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20090201
Inactivation of GABA transaminase by 3-chloro-1-(4-hydroxyphenyl)propan-1-one. Bioorganic & medicinal chemistry letters 20090201
Prolyl hydroxylases as regulators of cell metabolism. Biochemical Society transactions 20090201
Carnitine in the treatment of valproic acid-induced toxicity. Clinical toxicology (Philadelphia, Pa.) 20090201
Sugar regulation of plastid reversion in citrus epicarp is mediated through organic acid metabolism. Pakistan journal of biological sciences : PJBS 20090201
alpha-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ. Neuroscience 20090123
Reconstitution of Escherichia coli glutamine synthetase adenylyltransferase from N-terminal and C-terminal fragments of the enzyme. Biochemistry 20090120
Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology. Analytical biochemistry 20090115
Role of the mitochondrial sodium/calcium exchanger in neuronal physiology and in the pathogenesis of neurological diseases. Progress in neurobiology 20090112
Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents. Neuroscience 20090112
Carbon dioxide: a waste product in the catalytic cycle of alpha-ketoglutarate dependent halogenases prevents the formation of hydroxylated by-products. The journal of physical chemistry. B 20090108
Oxygen sensors at the crossroad of metabolism. Cell metabolism 20090107
The phosphatidylinositol-protein nanocomplex as a new biosensor for ecological monitoring and clinical diagnostic. Biosensors & bioelectronics 20090101
Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway. Molecular & cellular proteomics : MCP 20090101
Genetic manipulation of lysine catabolism in maize kernels. Plant molecular biology 20090101
Periplasmic cold expression and one-step purification of human dihydrolipoamide dehydrogenase. Protein expression and purification 20090101
Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum. Applied microbiology and biotechnology 20090101
Effect of dietary alpha-ketoglutarate on blood lipid profile during hypercholesterolaemia in rats. Scandinavian journal of clinical and laboratory investigation 20090101
Influence of all-trans-retinoic acid on oxoglutarate carrier via retinoylation reaction. Biochimica et biophysica acta 20090101
Nanoparticle-supported multi-enzyme biocatalysis with in situ cofactor regeneration. Journal of biotechnology 20090101
A pathway-specific microarray analysis highlights the complex and co-ordinated transcriptional networks of the developing grain of field-grown barley. Journal of experimental botany 20090101
How mitochondria produce reactive oxygen species. The Biochemical journal 20090101
Peroxidative damage of mitochondrial respiration is substrate-dependent. Physiological research 20090101
Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function. Chemical research in toxicology 20090101
Role of calcium in acclimation of the cyanobacterium Synechococcus elongatus PCC 7942 to nitrogen starvation. Microbiology (Reading, England) 20090101
Synthetic control of a fitness tradeoff in yeast nitrogen metabolism. Journal of biological engineering 20090101
Metabolic engineering of a reduced-genome strain of Escherichia coli for L-threonine production. Microbial cell factories 20090101
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. BMC medical genomics 20090101
Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells. Molecular vision 20090101
Imbalanced lignin biosynthesis promotes the sexual reproduction of homothallic oomycete pathogens. PLoS pathogens 20090101
Update of cell damage mechanisms in thiamine deficiency: focus on oxidative stress, excitotoxicity and inflammation. Alcohol and alcoholism (Oxford, Oxfordshire) 20090101
Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. PloS one 20090101
Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths. PLoS genetics 20090101
Comparative transcriptomic analysis of Porphyromonas gingivalis biofilm and planktonic cells. BMC microbiology 20090101
Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae. PLoS computational biology 20090101
Inter- and intra-individual variations of urinary endogenous metabolites in healthy male college students using (1)H NMR spectroscopy. Clinical chemistry and laboratory medicine 20090101
Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3. BMC systems biology 20090101
Analysis on relationship between extreme pathways and correlated reaction sets. BMC bioinformatics 20090101
LC/MS-based quantitative proteomic analysis of paraffin-embedded archival melanomas reveals potential proteomic biomarkers associated with metastasis. PloS one 20090101
Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis. Arthritis research & therapy 20090101
Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair. Arthritis research & therapy 20090101
Acid production by oral strains of Candida albicans and lactobacilli. Caries research 20090101
Genome sequence of the pathogenic intestinal spirochete brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine. PloS one 20090101
New therapeutic approach to Tourette Syndrome in children based on a randomized placebo-controlled double-blind phase IV study of the effectiveness and safety of magnesium and vitamin B6. Trials 20090101
The photosynthetic apparatus and its regulation in the aerobic gammaproteobacterium Congregibacter litoralis gen. nov., sp. nov. PloS one 20090101
Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases. Arthritis research & therapy 20090101
Metabolic profiles in urine reflect nephrotoxicity of sirolimus and cyclosporine following rat kidney transplantation. Nephron. Experimental nephrology 20090101
Identification of IbeR as a stationary-phase regulator in meningitic Escherichia coli K1 that carries a loss-of-function mutation in rpoS. Journal of biomedicine & biotechnology 20090101
Transcriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes. BMC genomics 20090101
Connecting extracellular metabolomic measurements to intracellular flux states in yeast. BMC systems biology 20090101
The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome. Proteome science 20090101
Potential mechanisms of muscle mitochondrial dysfunction in aging and obesity and cellular consequences. International journal of molecular sciences 20090101
Host iron binding proteins acting as niche indicators for Neisseria meningitidis. PloS one 20090101
Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane. PloS one 20090101
Choreography of the transcriptome, photophysiology, and cell cycle of a minimal photoautotroph, prochlorococcus. PloS one 20090101
Erythropoiesis stimulating agents and techniques: a challenge for doping analysts. Current medicinal chemistry 20090101
Chapter 17. Siderophore biosynthesis a substrate specificity assay for nonribosomal peptide synthetase-independent siderophore synthetases involving trapping of acyl-adenylate intermediates with hydroxylamine. Methods in enzymology 20090101
In vitro histone demethylase assays. Methods in molecular biology (Clifton, N.J.) 20090101
Advances in pharmacological strategies for the prevention of cataract development. Indian journal of ophthalmology 20090101
Transcriptomic and metabolic responses of Staphylococcus aureus exposed to supra-physiological temperatures. BMC microbiology 20090101
Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation. BMC psychiatry 20090101
Hypoxia. Hypoxia, hypoxia inducible factor and myeloid cell function. Arthritis research & therapy 20090101
Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources. PloS one 20090101
Expression profiling of genes involved in collagen turnover in tendons from cerebral palsy patients. Connective tissue research 20090101
Proteomic and network analysis characterize stage-specific metabolism in Trypanosoma cruzi. BMC systems biology 20090101
Effect of a glucose impulse on the CcpA regulon in Staphylococcus aureus. BMC microbiology 20090101
Proteomics of Porphyromonas gingivalis within a model oral microbial community. BMC microbiology 20090101
Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis. Arthritis research & therapy 20090101
Genomic characterization of methanomicrobiales reveals three classes of methanogens. PloS one 20090101
Modeling heterocyst pattern formation in cyanobacteria. BMC bioinformatics 20090101
A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability. Molecular systems biology 20090101
Activity and gene expression profile of certain antioxidant enzymes in different organs of rats after subacute cyanide exposure: effect of alpha-ketoglutarate. Drug and chemical toxicology 20090101
Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea. Genome biology 20090101
Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. PloS one 20090101
Synergistic effect of imp/ostA and msbA in hydrophobic drug resistance of Helicobacter pylori. BMC microbiology 20090101
Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions. BMC systems biology 20090101
Genome-wide analysis of the RpoN regulon in Geobacter sulfurreducens. BMC genomics 20090101
Expression of genes involved in nitrogen assimilation and the C/N balance sensing in Prochlorococcus sp. strain SS120. Gene expression 20090101
Adherence to the Mediterranean diet moderates the association of aminotransferases with the prevalence of the metabolic syndrome; the ATTICA study. Nutrition & metabolism 20090101
Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum. Microbial cell factories 20090101
Expression of prolyl 3-hydroxylase genes in embryonic and adult mouse tissues. Cell structure and function 20090101
Brucella microti: the genome sequence of an emerging pathogen. BMC genomics 20090101
Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis. BMC genomics 20090101
Genome-scale gene/reaction essentiality and synthetic lethality analysis. Molecular systems biology 20090101
Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli. Molecular systems biology 20090101
Potentials and limitations of microorganisms as renal failure biotherapeutics. Biologics : targets & therapy 20090101
Synthesis of hydrazones derivatives of quinoxalinone--prospective antimicrobial and antiinflammatory agents. Acta poloniae pharmaceutica 20090101
Pathway analysis for intracellular Porphyromonas gingivalis using a strain ATCC 33277 specific database. BMC microbiology 20090101
Nutrition controls mitochondrial biogenesis in the Drosophila adipose tissue through Delg and cyclin D/Cdk4. PloS one 20090101
Determination of enzymatic source of alanine aminotransferase activity in serum from dogs with liver injury. Journal of pharmacological and toxicological methods 20090101
Time-resolved transcriptome analysis of Bacillus subtilis responding to valine, glutamate, and glutamine. PloS one 20090101
Genome-scale comparison and constraint-based metabolic reconstruction of the facultative anaerobic Fe(III)-reducer Rhodoferax ferrireducens. BMC genomics 20090101
LKR/SDH plays important roles throughout the tick life cycle including a long starvation period. PloS one 20090101
Metabolic fluxes in the central carbon metabolism of Dinoroseobacter shibae and Phaeobacter gallaeciensis, two members of the marine Roseobacter clade. BMC microbiology 20090101
Mitigation of mitochondrial dysfunction and regulation of eNOS expression during experimental myocardial necrosis by alpha-mangostin, a xanthonic derivative from Garcinia mangostana. Drug and chemical toxicology 20090101
An ATP and oxalate generating variant tricarboxylic acid cycle counters aluminum toxicity in Pseudomonas fluorescens. PloS one 20090101
The amidase domain of lipoamidase specifically inactivates lipoylated proteins in vivo. PloS one 20090101
Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells. Journal of biomedical science 20090101
Tumor suppressor function of Syk in human MCF10A in vitro and normal mouse mammary epithelium in vivo. PloS one 20090101
Anaesthetic management of an adult patient with DOOR syndrome: a case report. Cases journal 20090101
Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries. BMC genomics 20090101
Transcription analysis of central metabolism genes in Escherichia coli. Possible roles of sigma38 in their expression, as a response to carbon limitation. PloS one 20090101
Sigma factors for cyanobacterial transcription. Gene regulation and systems biology 20090101
An insight into the role of phosphotransacetylase (pta) and the acetate/acetyl-CoA node in Escherichia coli. Microbial cell factories 20090101
Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons. BMC genomics 20090101
Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches. PloS one 20090101
13C-metabolic flux ratio and novel carbon path analyses confirmed that Trichoderma reesei uses primarily the respirative pathway also on the preferred carbon source glucose. BMC systems biology 20090101
Regulation of intestinal epithelial cells transcriptome by enteric glial cells: impact on intestinal epithelial barrier functions. BMC genomics 20090101
Ribosome and transcript copy numbers, polysome occupancy and enzyme dynamics in Arabidopsis. Molecular systems biology 20090101
An integrated analysis of molecular acclimation to high light in the marine diatom Phaeodactylum tricornutum. PloS one 20090101
The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels. PloS one 20090101
Mechanism of dinitrochlorobenzene-induced dermatitis in mice: role of specific antibodies in pathogenesis. PloS one 20090101
Evolution by leaps: gene duplication in bacteria. Biology direct 20090101
A genome-wide survey for host response of silkworm, Bombyx mori during pathogen Bacillus bombyseptieus infection. PloS one 20090101
Coenzyme Q10 effects in neurodegenerative disease. Neuropsychiatric disease and treatment 20090101
Effective identification of conserved pathways in biological networks using hidden Markov models. PloS one 20090101
The hydrogenosomes of Psalteriomonas lanterna. BMC evolutionary biology 20090101
The emerging role of cardiovascular risk factor-induced mitochondrial dysfunction in atherogenesis. Journal of biomedical science 20090101
Proteome analysis of Aspergillus niger: lactate added in starch-containing medium can increase production of the mycotoxin fumonisin B2 by modifying acetyl-CoA metabolism. BMC microbiology 20090101
Extramitochondrial Ca2+ in the nanomolar range regulates glutamate-dependent oxidative phosphorylation on demand. PloS one 20090101
Estradiol stimulates vasodilatory and metabolic pathways in cultured human endothelial cells. PloS one 20090101
Folate nutrition is related to neuropsychological functions in the elderly. Nutrition research and practice 20090101
Microarray analysis of retinal gene expression in Egr-1 knockout mice. Molecular vision 20090101
Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis. BMC genomics 20090101
Proteomic analysis of regenerating mouse liver following 50% partial hepatectomy. Proteome science 20090101
Tuning microbial hosts for membrane protein production. Microbial cell factories 20090101
Transcriptional adaptations following exercise in thoroughbred horse skeletal muscle highlights molecular mechanisms that lead to muscle hypertrophy. BMC genomics 20090101
Mechanisms of c-myc degradation by nickel compounds and hypoxia. PloS one 20090101
Amino acids - Guidelines on Parenteral Nutrition, Chapter 4. German medical science : GMS e-journal 20090101
Oxidative stress and antioxidant defenses in asthmatic murine model exposed to printer emissions and environmental tobacco smoke. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20090101
Effects of long-term oxygen treatment on alpha-ketoglutarate dehydrogenase activity and oxidative modifications in mitochondria of the guinea pig heart. European journal of medical research 20090101
Defective glycinergic synaptic transmission in zebrafish motility mutants. Frontiers in molecular neuroscience 20090101
Treatment advances in Alzheimer's disease based on the oxidative stress model. F1000 medicine reports 20090101
Xylella fastidiosa gene expression analysis by DNA microarrays. Genetics and molecular biology 20090101
Molecular cloning and function analysis of an anthocyanidin synthase gene from Ginkgo biloba, and its expression in abiotic stress responses. Molecules and cells 20081231
Specificity and reactivity in menaquinone biosynthesis: the structure of Escherichia coli MenD (2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase). Journal of molecular biology 20081231
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha. The Biochemical journal 20081215
1,25(OH)2D3 regulates collagen quality in an osteoblastic cell culture system. Biochemical and biophysical research communications 20081212
Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multienzyme complex. Structure (London, England : 1993) 20081212
Effect of alpha-ketoglutarate on monoclonal antibody production of hybridoma cell lines in serum-free and serum-containing medium. Applied biochemistry and biotechnology 20081201
Metabolic cycling in control of glucose-stimulated insulin secretion. American journal of physiology. Endocrinology and metabolism 20081201
Genome-scale model for Clostridium acetobutylicum: Part I. Metabolic network resolution and analysis. Biotechnology and bioengineering 20081201
Coordination changes and auto-hydroxylation of FIH-1: uncoupled O2-activation in a human hypoxia sensor. Journal of inorganic biochemistry 20081201
Inhibition of 2-oxoglutarate dehydrogenase in potato tuber suggests the enzyme is limiting for respiration and confirms its importance in nitrogen assimilation, Plant physiology 20081201
Metabolome phenotyping of inorganic carbon limitation in cells of the wild type and photorespiratory mutants of the cyanobacterium Synechocystis sp. strain PCC 6803. Plant physiology 20081201
Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo. American journal of physiology. Heart and circulatory physiology 20081201
Arginine and nitrogen storage. Current opinion in structural biology 20081201
Towards understanding the nitrogen signal transduction for nif gene expression in Klebsiella pneumoniae. The FEBS journal 20081201
PII, the key regulator of nitrogen metabolism in the cyanobacteria. Science in China. Series C, Life sciences 20081201
[Metabonomic profile of urine from rats administrated with different treatment period of rifampin]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20081201
Spatial distribution of cytosolic NADP(+)-isocitrate dehydrogenase in pine embryos and seedlings. Tree physiology 20081201
A dialogue between the hypoxia-inducible factor and the tumor microenvironment. Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201
Protective effect of aspartate and glutamate on cardiac mitochondrial function during myocardial infarction in experimental rats. Chemico-biological interactions 20081125
Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme. Biochemistry 20081118
Alpha-ketoglutarate oxidoreductase, an essential salvage enzyme of energy metabolism, in coccoid form of Helicobacter pylori. Biochemical and biophysical research communications 20081107
Isolation of a novel family of genes related to 2-oxoglutarate-dependent dioxygenases from soybean and analysis of their expression during root nodule senescence. Journal of plant physiology 20081101
Crystal structure of DFA0005 complexed with alpha-ketoglutarate: a novel member of the ICL/PEPM superfamily from alkali-tolerant Deinococcus ficus. Proteins 20081101
The impact of N-nitrosomelatonin as nitric oxide donor in cell culture experiments. Journal of pineal research 20081101
Endurance exercise as a countermeasure for aging. Diabetes 20081101
Complex I dysfunction redirects cellular and mitochondrial metabolism in Arabidopsis. Plant physiology 20081101
Conservation of notochord gene expression across chordates: insights from the Leprecan gene family. Genesis (New York, N.Y. : 2000) 20081101
Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation. Journal of immunology (Baltimore, Md. : 1950) 20081101
Carbon source-dependent modulation of NADP-glutamate dehydrogenases in isophthalate-degrading Pseudomonas aeruginosa strain PP4, Pseudomonas strain PPD and Acinetobacter lwoffii strain ISP4. Microbiology (Reading, England) 20081101
Ornithine delta-aminotransferase: An enzyme implicated in salt tolerance in higher plants. Plant signaling & behavior 20081101
A stopped flow transient kinetic analysis of substrate binding and catalysis in Escherichia coli D-3-phosphoglycerate dehydrogenase. The Journal of biological chemistry 20081031
Auto-hydroxylation of FIH-1: an Fe(ii), alpha-ketoglutarate-dependent human hypoxia sensor. Chemical communications (Cambridge, England) 20081021
Metabolic pathways in Anopheles stephensi mitochondria. The Biochemical journal 20081015
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. FEBS letters 20081015
Novel roles for collagens in wiring the vertebrate nervous system. Current opinion in cell biology 20081001
Impact of short- and medium-chain organic acids, acylcarnitines, and acyl-CoAs on mitochondrial energy metabolism. Biochimica et biophysica acta 20081001
Biochemical and genetic characterization of Arabidopsis flavanone 3beta-hydroxylase. Plant physiology and biochemistry : PPB 20081001
Identification of target genes for a MYB-type anthocyanin regulator in Gerbera hybrida. Journal of experimental botany 20081001
Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart. The FEBS journal 20081001
Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. Nature genetics 20081001
Variation of metabolic profiles in developing maize kernels up- and down-regulated for the hda101 gene. Journal of experimental botany 20081001
The long-term effect of alpha-ketoglutarate, given early in postnatal life, on both growth and various bone parameters in pigs. Journal of animal physiology and animal nutrition 20081001
Creatine, arginine alpha-ketoglutarate, amino acids, and medium-chain triglycerides and endurance and performance. International journal of sport nutrition and exercise metabolism 20081001
Toxicology. Indian journal of pharmacology 20081001
New method for reducing the binding power of sweet white wines. Journal of agricultural and food chemistry 20080924
Evidence that two enzyme-derived histidine ligands are sufficient for iron binding and catalysis by factor inhibiting HIF (FIH). The Journal of biological chemistry 20080919
Analysis of selected carbonyl oxidation products in wine by liquid chromatography with diode array detection. Analytica chimica acta 20080919
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. The Journal of biological chemistry 20080905
Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction. Protein science : a publication of the Protein Society 20080901
Effects of thiamine and benfotiamine on intracellular glucose metabolism and relevance in the prevention of diabetic complications. Acta diabetologica 20080901
Biochemical characterization of stage-specific isoforms of aspartate aminotransferases from Trypanosoma cruzi and Trypanosoma brucei. Molecular and biochemical parasitology 20080901
Dynamic states of the DNA repair enzyme AlkB regulate product release. EMBO reports 20080901
Ethylene production by metabolic engineering of the yeast Saccharomyces cerevisiae. Metabolic engineering 20080901
Long-term effects of corticosterone on behavior, oxidative and energy metabolism of parietotemporal cerebral cortex and hippocampus of rats: comparison to intracerebroventricular streptozotocin. Journal of neural transmission (Vienna, Austria : 1996) 20080901
Reduction of mitochondrial oxidative damage and improved mitochondrial efficiency by administration of crocetin against benzo[a]pyrene induced experimental animals. Biological & pharmaceutical bulletin 20080901
Lipid lowering effect of antioxidant alpha-lipoic Acid in experimental atherosclerosis. Journal of clinical biochemistry and nutrition 20080901
Purification and characteristics of functional properties of soluble nucleoside triphosphatase (apyrase) from bovine brain. Biochemistry. Biokhimiia 20080901
alpha-Ketoglutarate biosynthesis in wild and industrial strains of Lactococcus lactis. Letters in applied microbiology 20080901
All-atom replica exchange molecular simulation of protein BBL. Proteins 20080815
Huperzine A attenuates mitochondrial dysfunction after middle cerebral artery occlusion in rats. Journal of neuroscience research 20080815
Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle: II. Heterogeneity of metabolite labeling pattern. The Journal of biological chemistry 20080808
Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle. I. Interrelation between gluconeogenesis and cataplerosis; formation of methoxamates from aminooxyacetate and ketoacids. The Journal of biological chemistry 20080808
Stimuli-responsive polyguanidino-oxanorbornene membrane transporters as multicomponent sensors in complex matrices. Journal of the American Chemical Society 20080806
Glutamate availability is important in intramuscular amino acid metabolism and TCA cycle intermediates but does not affect peak oxidative metabolism. Journal of applied physiology (Bethesda, Md. : 1985) 20080801
Immobilization-stabilization of a new recombinant glutamate dehydrogenase from Thermus thermophilus. Applied microbiology and biotechnology 20080801
Difference in metabolite levels between photoautotrophic and photomixotrophic cultures of Synechocystis sp. PCC 6803 examined by capillary electrophoresis electrospray ionization mass spectrometry. Journal of experimental botany 20080801
Glutamate export at the choroid plexus in health, thiamin deficiency, and ethanol intoxication: review and hypothesis. Alcoholism, clinical and experimental research 20080801
Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II. Bioscience reports 20080801
The role of oxidative stress in the development of congestive heart failure in a chicken genotype selected for rapid growth. Avian pathology : journal of the W.V.P.A 20080801
Beta-cell alpha-ketoglutarate hydroxylases may acutely participate in insulin secretion. Metabolism: clinical and experimental 20080801
Interaction of the signal transduction protein GlnJ with the cellular targets AmtB1, GlnE and GlnD in Rhodospirillum rubrum: dependence on manganese, 2-oxoglutarate and the ADP/ATP ratio. Microbiology (Reading, England) 20080801
Inactivation of the general transcription factor TnrA in Bacillus subtilis by proteolysis. Microbiology (Reading, England) 20080801
Identification and functional analysis of light-responsive unique genes and gene family members in rice. PLoS genetics 20080801
Biological effects of 2-oxoglutarate with particular emphasis on the regulation of protein, mineral and lipid absorption/metabolism, muscle performance, kidney function, bone formation and cancerogenesis, all viewed from a healthy ageing perspective state of the art--review article. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801
Muscle contraction and force: the importance of an ancillary network, nutrient supply and waste removal. International journal of molecular sciences 20080801
Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line. The Journal of biological chemistry 20080725
Evolution of quaternary structure in a homotetrameric enzyme. Journal of molecular biology 20080718
Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV. The Journal of biological chemistry 20080711
Polyhydroxyalkanoate production from whey by Pseudomonas hydrogenovora. Bioresource technology 20080701
High doses of nicotinamide prevent oxidative mitochondrial dysfunction in a cellular model and improve motor deficit in a Drosophila model of Parkinson's disease. Journal of neuroscience research 20080701
Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Molecular & cellular proteomics : MCP 20080701
Baicalein induces functional hypoxia-inducible factor-1alpha and angiogenesis. Molecular pharmacology 20080701
Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria. Molecular microbiology 20080701
Sugar signalling mediates cluster root formation and phosphorus starvation-induced gene expression in white lupin. Journal of experimental botany 20080701
Identification and transcriptional profiling of Pseudomonas putida genes involved in furoic acid metabolism. FEMS microbiology letters 20080701
Detection and identification of novel metabolomic biomarkers in preeclampsia. Reproductive sciences (Thousand Oaks, Calif.) 20080701
Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry 20080701
An oxygen molecular sensor, the HIF prolyl 4-hydroxylase, in the marine protist Perkinsus olseni. Protist 20080701
A candidate gene survey of quantitative trait loci affecting chemical composition in tomato fruit. Journal of experimental botany 20080701
Natural product juglone targets three key enzymes from Helicobacter pylori: inhibition assay with crystal structure characterization. Acta pharmacologica Sinica 20080701
Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery. PLoS neglected tropical diseases 20080701
Inactivation of spkD, encoding a Ser/Thr kinase, affects the pool of the TCA cycle metabolites in Synechocystis sp. strain PCC 6803. Microbiology (Reading, England) 20080701
An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation. Free radical research 20080701
Truncation of the krebs cycle during hypoglycemic coma. Medicinal chemistry (Shariqah (United Arab Emirates)) 20080701
A Zn-surprise in Ehlers-Danlos syndrome. Matrix biology : journal of the International Society for Matrix Biology 20080701
[Enhancing alpha-ketoglutaric acid production in Torulopsis glabrata: increase of acetyl-CoA availability]. Wei sheng wu xue bao = Acta microbiologica Sinica 20080701
Effect of poly(D, L-lactic acid) nanoparticles as triptolide carrier on abating rats renal toxicity by NMR-based metabolic analysis. Journal of nanoscience and nanotechnology 20080701
PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer. British journal of cancer 20080617
Regulation of hypoxia-inducible factor-1alpha by NF-kappaB. The Biochemical journal 20080615
Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases. Neuroscience 20080602
Arabidopsis DMR6 encodes a putative 2OG-Fe(II) oxygenase that is defense-associated but required for susceptibility to downy mildew. The Plant journal : for cell and molecular biology 20080601
Structural bases for the specific interactions between the E2 and E3 components of the Thermus thermophilus 2-oxo acid dehydrogenase complexes. Journal of biochemistry 20080601
Mitochondrial respiratory pathways modulate nitrate sensing and nitrogen-dependent regulation of plant architecture in Nicotiana sylvestris. The Plant journal : for cell and molecular biology 20080601
Hepatic mitochondrial transport of glutathione: studies in isolated rat liver mitochondria and H4IIE rat hepatoma cells. Archives of biochemistry and biophysics 20080601
Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes. American journal of physiology. Endocrinology and metabolism 20080601
Anaplerosis from glucose, alpha-ketoisocaproate, and pyruvate in pancreatic islets, INS-1 cells and liver mitochondria. Molecular and cellular biochemistry 20080601
Improvement of poly(gamma-glutamic acid) biosynthesis and redistribution of metabolic flux with the presence of different additives in Bacillus subtilis CGMCC 0833. Applied microbiology and biotechnology 20080601
Gamma-hydroxybutyrate accumulation in Arabidopsis and tobacco plants is a general response to abiotic stress: putative regulation by redox balance and glyoxylate reductase isoforms. Journal of experimental botany 20080601
Concerted modulation of alanine and glutamate metabolism in young Medicago truncatula seedlings under hypoxic stress. Journal of experimental botany 20080601
Specialization of the paralogue LYS21 determines lysine biosynthesis under respiratory metabolism in Saccharomyces cerevisiae. Microbiology (Reading, England) 20080601
Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum. Acta crystallographica. Section D, Biological crystallography 20080601
Degradation of pyrimidines in Saccharomyces kluyveri: transamination of beta-alanine. Nucleosides, nucleotides & nucleic acids 20080601
[Global expression profiling of Saccharomyces cerevisiae: metabolic remodeling in post-log phase]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080601
Changes in ECG and enzyme activity in rat heart after myocardial infarction: effect of TPP and MnCl2. Journal of physiology and biochemistry 20080601
Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily. Journal of molecular biology 20080530
Effect of mangiferin on benzo(a)pyrene induced lung carcinogenesis in experimental Swiss albino mice. Natural product research 20080520
Does inhibition of degradation of hypoxia-inducible factor (HIF) alpha always lead to activation of HIF? Lessons learnt from the effect of proteasomal inhibition on HIF activity. Journal of cellular biochemistry 20080515
Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae. Biochemistry 20080513
Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins. Proteins 20080501
Remote renal preconditioning-induced cardioprotection: a key role of hypoxia inducible factor-prolyl 4-hydroxylases. Molecular and cellular biochemistry 20080501
2-Oxoglutarate-dependent oxygenases control hepcidin gene expression. Journal of hepatology 20080501
Metabolite profiling reveals distinct changes in carbon and nitrogen metabolism in phosphate-deficient barley plants (Hordeum vulgare L.). Plant & cell physiology 20080501
The human side of hypoxia-inducible factor. British journal of haematology 20080501
Structure-function studies of glutamate synthases: a class of self-regulated iron-sulfur flavoenzymes essential for nitrogen assimilation. IUBMB life 20080501
(-)Epigallocatechin-gallate (EGCG) prevents mitochondrial damage in isoproterenol-induced cardiac toxicity in albino Wistar rats: a transmission electron microscopic and in vitro study. Pharmacological research 20080501
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS genetics 20080501
Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells. The Journal of biological chemistry 20080418
Kinetics and mechanism of degradation of p-chloronitrobenzene in water by ozonation. Journal of hazardous materials 20080415
Cell free expression and functional reconstitution of eukaryotic drug transporters. Biochemistry 20080415
Alterations of flavonoid biosynthesis in young grapevine (Vitis vinifera L.) leaves, flowers, and berries induced by the dioxygenase inhibitor prohexadione-Ca. Journal of agricultural and food chemistry 20080409
Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease. Biochimica et biophysica acta 20080401
Apparent negative co-operativity and substrate inhibition in overexpressed glutamate dehydrogenase from Escherichia coli. FEMS microbiology letters 20080401
Metabolomics reveals unique and shared metabolic changes in response to heat shock, freezing and desiccation in the Antarctic midge, Belgica antarctica. Journal of insect physiology 20080401
The absorption, tissue distribution and excretion of enteraly administered alpha-ketoglutarate in rats. Journal of animal physiology and animal nutrition 20080401
Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines. The American journal of pathology 20080401
Modification of respiratory-chain enzyme activities in brown adipose tissue mitochondria by idebenone (hydroxydecyl-ubiquinone). Journal of bioenergetics and biomembranes 20080401
Different responses of the GlnB and GlnZ proteins upon in vitro uridylylation by the Azospirillum brasilense GlnD protein. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20080401
Predicting co-complexed protein pairs from heterogeneous data. PLoS computational biology 20080401
Structural-dynamical properties of the transmembrane segment VI of the mitochondrial oxoglutarate carrier studied by site directed spin-labeling. Molecular membrane biology 20080401
Robustness in Escherichia coli glutamate and glutamine synthesis studied by a kinetic model. Journal of biological physics 20080401
Metabonomic study on the toxicity of Hei-Shun-Pian, the processed lateral root of Aconitum carmichaelii Debx. (Ranunculaceae). Journal of ethnopharmacology 20080328
Comparative quantum mechanics/molecular mechanics (QM/MM) and density functional theory calculations on the oxo-iron species of taurine/alpha-ketoglutarate dioxygenase. The journal of physical chemistry. A 20080320
Use of Lactobacillus plantarum fermentation products in bread-making to prevent Bacillus subtilis ropy spoilage. International journal of food microbiology 20080320
Molecular identification of three Arabidopsis thaliana mitochondrial dicarboxylate carrier isoforms: organ distribution, bacterial expression, reconstitution into liposomes and functional characterization. The Biochemical journal 20080315
Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors. Bioorganic & medicinal chemistry letters 20080315
An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A. Biochemistry 20080304
Zinc toxicity alters mitochondrial metabolism and leads to decreased ATP production in hepatocytes. Journal of applied toxicology : JAT 20080301
Preventing cell death induced by carbonyl stress, oxidative stress or mitochondrial toxins with vitamin B anti-AGE agents. Molecular nutrition & food research 20080301
Profiling of external metabolites during production of hantavirus nucleocapsid protein with recombinant Saccharomyces cerevisiae. Biotechnology letters 20080301
Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins. Placenta 20080301
Expanding chemical biology of 2-oxoglutarate oxygenases. Nature chemical biology 20080301
Metabolism of halophilic archaea. Extremophiles : life under extreme conditions 20080301
Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. PLoS genetics 20080301
A Mouse Model of Metabolic Syndrome; Increase in Visceral Adipose Tissue Precedes the Development of Fatty Liver and Insulin Resistance in High-Fat Diet-Fed Male KK/Ta Mice. Journal of clinical biochemistry and nutrition 20080301
Bofutsushosan, an Oriental Herbal Medicine, Attenuates the Weight Gain of White Adipose Tissue and the Increased Size of Adipocytes Associated with the Increase in Their Expression of Uncoupling Protein 1 in High-Fat Diet-Fed Male KK/Ta mice. Journal of clinical biochemistry and nutrition 20080301
Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases. The Journal of biological chemistry 20080215
1H NMR-based metabonomic analysis of urine from young spontaneously hypertensive rats. Journal of pharmaceutical and biomedical analysis 20080213
Off-pathway, oxygen-dependent thiamine radical in the Krebs cycle. Journal of the American Chemical Society 20080206
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Formation of diacetyl and acetoin by Lactococcus lactis via aspartate catabolism. Journal of applied microbiology 20080101
Fuel-induced amplification of insulin secretion in mouse pancreatic islets exposed to a high sulfonylurea concentration: role of the NADPH/NADP+ ratio. Diabetologia 20080101
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The implausibility of metabolic cycles on the prebiotic Earth. PLoS biology 20080101
Primary biliary cirrhosis. Orphanet journal of rare diseases 20080101
Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity. BMC molecular biology 20080101
Attenuation of Biochemical Parameters in Streptozotocin-induced Diabetic Rats by Oral Administration of Extracts and Fractions of Cephalotaxus sinensis. Journal of clinical biochemistry and nutrition 20080101
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Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure. PloS one 20080101
MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology. PloS one 20080101
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Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. PloS one 20080101
Characterization of human mesenchymal stem cell secretome at early steps of adipocyte and osteoblast differentiation. BMC molecular biology 20080101
Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia. BMC microbiology 20080101
Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP. PloS one 20080101
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Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major. Molecular systems biology 20080101
Transcription of hexose transporters of Saccharomyces cerevisiae is affected by change in oxygen provision. BMC microbiology 20080101
Increase in the contribution of transamination to the respiration of mitochondria during arousal. Cryo letters 20080101
A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery. BMC cell biology 20080101
Malate metabolism in Hoya carnosa mitochondria and its role in photosynthesis during CAM phase III. Journal of experimental botany 20080101
Novel Anticancer Platinum(IV) Complexes with Adamantylamine: Their Efficiency and Innovative Chemotherapy Strategies Modifying Lipid Metabolism. Metal-based drugs 20080101
Dietary alpha-ketoglutarate reduces gastrectomy-evoked loss of calvaria and trabecular bone in female rats. Scandinavian journal of gastroenterology 20080101
Assessment of CcpA-mediated catabolite control of gene expression in Bacillus cereus ATCC 14579. BMC microbiology 20080101
Studies with leucine, beta-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion. Biochimica et biophysica acta 20080101
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Simultaneous gene expression profiling in human macrophages infected with Leishmania major parasites using SAGE. BMC genomics 20080101
Expression of Brugmansia candida Hyoscyamine 6beta-Hydroxylase gene in Saccharomyces cerevisiae and its potential use as biocatalyst. Microbial cell factories 20080101
Divergence of canonical danger signals: the genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide. BMC immunology 20080101
Formate hydrogenlyase in the hyperthermophilic archaeon, Thermococcus litoralis. BMC microbiology 20080101
Yeast mitochondrial biogenesis: a role for the PUF RNA-binding protein Puf3p in mRNA localization. PloS one 20080101
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Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives. BMC pharmacology 20080101
Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins. BMC genomics 20080101
Early vertebrate chromosome duplications and the evolution of the neuropeptide Y receptor gene regions. BMC evolutionary biology 20080101
Nitrogen metabolism in haloarchaea. Saline systems 20080101
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. BMC medical genetics 20080101
A novel strategy involved in [corrected] anti-oxidative defense: the conversion of NADH into NADPH by a metabolic network. PloS one 20080101
Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways. Journal of biomedicine & biotechnology 20080101
Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study. PloS one 20080101
[The role of the functional state of kidney mitochondria in predisposition of hydronephrotic rabits to gentamicin nephrotoxicity]. Eksperimental'naia i klinicheskaia farmakologiia 20080101
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. Advanced drug delivery reviews 20080101
Yeast cell factories for fine chemical and API production. Microbial cell factories 20080101
Altered gene expression in highly purified enterocytes from patients with active coeliac disease. BMC genomics 20080101
Complete genome of Phenylobacterium zucineum--a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562. BMC genomics 20080101
Gene expression and functional studies of the optic nerve head astrocyte transcriptome from normal African Americans and Caucasian Americans donors. PloS one 20080101
Adenine nucleotide translocator transports haem precursors into mitochondria. PloS one 20080101
Global self-organization of the cellular metabolic structure. PloS one 20080101
An extension of the coevolution theory of the origin of the genetic code. Biology direct 20080101
Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia. BMC genomics 20080101
'Fat mass and obesity associated' gene (FTO): no significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents. BMC medical genetics 20080101
Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover. Molecular cancer 20080101
Simplivariate models: ideas and first examples. PloS one 20080101
Iterative reconstruction of a global metabolic model of Acinetobacter baylyi ADP1 using high-throughput growth phenotype and gene essentiality data. BMC systems biology 20080101
A construct with fluorescent indicators for conditional expression of miRNA. BMC biotechnology 20080101
Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes. Molecular systems biology 20080101
Targeting aspartate aminotransferase in breast cancer. Breast cancer research : BCR 20080101
Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes. Molecular cancer 20080101
Glucose uptake and its effect on gene expression in prochlorococcus. PloS one 20080101
Co-regulation analysis of closely linked genes identifies a highly recurrent gain on chromosome 17q25.3 in prostate cancer. BMC cancer 20080101
The transcriptomic signature of fasting murine liver. BMC genomics 20080101
A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans. Genome biology 20080101
Active transport of glutamate in Leishmania (Leishmania) amazonensis. The Journal of eukaryotic microbiology 20080101
The integrated analysis of metabolic and protein interaction networks reveals novel molecular organizing principles. BMC systems biology 20080101
Growth of Yersinia pseudotuberculosis in human plasma: impacts on virulence and metabolic gene expression. BMC microbiology 20080101
Comparative genomic analysis of carbon and nitrogen assimilation mechanisms in three indigenous bioleaching bacteria: predictions and validations. BMC genomics 20080101
Comparative genomics of vesicomyid clam (Bivalvia: Mollusca) chemosynthetic symbionts. BMC genomics 20080101
Multivariate gene expression analysis reveals functional connectivity changes between normal/tumoral prostates. BMC systems biology 20080101
Dietary supplementation with phytohemagglutinin in combination with alpha-ketoglutarate limits the excretion of nitrogen via urinary tract. Annals of agricultural and environmental medicine : AAEM 20080101
Response of the cytoplasmic and membrane proteome of Corynebacterium glutamicum ATCC 13032 to pH changes. BMC microbiology 20080101
Comparative analysis of fatty acid desaturases in cyanobacterial genomes. Comparative and functional genomics 20080101
Metabolic pathway alignment between species using a comprehensive and flexible similarity measure. BMC systems biology 20080101
Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets. Annals of medicine 20080101
Three-dimensional culture for monoclonal antibody production by hybridoma cells immobilized in macroporous gel particles. Biotechnology progress 20080101
[Transamination in the mechanism of protection of mitochondria from Ca2+ overload]. Biomeditsinskaia khimiia 20080101
NAD-Malic Enzyme Affects Nitrogen Fixing Activity of Bradyrhizobium japonicum USDA 110 Bacteroids in Soybean Nodules. Microbes and environments 20080101
Pyruvate-sensitive AOX exists as a non-covalently associated dimer in the homeothermic spadix of the skunk cabbage, Symplocarpus renifolius. FEBS letters 20071222
The active site of an algal prolyl 4-hydroxylase has a large structural plasticity. The Journal of biological chemistry 20071221
Succinate inhibition of alpha-ketoglutarate-dependent enzymes in a yeast model of paraganglioma. Human molecular genetics 20071215
Crystal structure of the non-heme iron dioxygenase PtlH in pentalenolactone biosynthesis. The Journal of biological chemistry 20071214
NifI inhibits nitrogenase by competing with Fe protein for binding to the MoFe protein. Biochemical and biophysical research communications 20071214
New methodology for removing carbonyl compounds from sweet wines. Journal of agricultural and food chemistry 20071212
Enantiomers of 4-amino-3-fluorobutanoic acid as substrates for gamma-aminobutyric acid aminotransferase. Conformational probes for GABA binding. Biochemistry 20071204
Enhanced [3H] glutamate binding in the cerebellum of insulin-induced hypoglycaemic and streptozotocin-induced diabetic rats. Cellular and molecular neurobiology 20071201
Control of key metabolic intersections in Bacillus subtilis. Nature reviews. Microbiology 20071201
Enzyme substrate recognition in oxygen sensing: how the HIF trap snaps. The Biochemical journal 20071201
DOOR syndrome: clinical report, literature review and discussion of natural history. American journal of medical genetics. Part A 20071201
Ternary complex formation between AmtB, GlnZ and the nitrogenase regulatory enzyme DraG reveals a novel facet of nitrogen regulation in bacteria. Molecular microbiology 20071201
Harnessing hypoxic adaptation to prevent, treat, and repair stroke. Journal of molecular medicine (Berlin, Germany) 20071201
Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. PLoS genetics 20071201
Integrated NMR-based metabonomic investigation of early metabolic effects of ethylene glycol monomethyl ether (EGME) on male reproductive organs in rats. The Journal of toxicological sciences 20071201
[Metabonomics profile of urine from rats administrated with different treatment period of isoniazid]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20071201
Computational design of digital and memory biological devices. Systems and synthetic biology 20071201
Structural characterization of the transmembrane segments of the mitochondrial oxoglutarate carrier (OGC) by NMR spectroscopy. The Italian journal of biochemistry 20071201
Grape seed proanthocyanidins ameliorates isoproterenol-induced myocardial injury in rats by stabilizing mitochondrial and lysosomal enzymes: an in vivo study. Life sciences 20071130
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. Science (New York, N.Y.) 20071130
Inhibitory properties of nerve-specific human glutamate dehydrogenase isozyme by chloroquine. Journal of biochemistry and molecular biology 20071130
Preconditioning results in S-nitrosylation of proteins involved in regulation of mitochondrial energetics and calcium transport. Circulation research 20071126
CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases. Journal of the American Chemical Society 20071121
Role of rat organic anion transporter 3 (Oat3) in the renal basolateral transport of glutathione. Chemico-biological interactions 20071120
Mitochondrial transport proteins of the brain. Journal of neuroscience research 20071115
The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin. The EMBO journal 20071114
Escherichia coli PII signal transduction protein controlling nitrogen assimilation acts as a sensor of adenylate energy charge in vitro. Biochemistry 20071113
Spectroscopic evidence for a high-spin Br-Fe(IV)-oxo intermediate in the alpha-ketoglutarate-dependent halogenase CytC3 from Streptomyces. Journal of the American Chemical Society 20071107
Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry 20071106
The impact of PHB accumulation on L-glutamate production by recombinant Corynebacterium glutamicum. Journal of biotechnology 20071101
Antimitochondrial antibodies in acute liver failure: implications for primary biliary cirrhosis. Hepatology (Baltimore, Md.) 20071101
The impact of preoperative micronutrient supplementation in lung surgery. A prospective randomized trial of oral supplementation of combined alpha-ketoglutaric acid and 5-hydroxymethylfurfural. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20071101
Osteoma of the calvaria in L-2-hydroxyglutaric aciduria. Journal of inherited metabolic disease 20071101
Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis. Nature 20071101
Global gene expression profiling of wild type and lysC knockout Escherichia coli W3110. FEMS microbiology letters 20071101
From endosymbiont to host-controlled organelle: the hijacking of mitochondrial protein synthesis and metabolism. PLoS computational biology 20071101
Osmotically induced synthesis of the compatible solute hydroxyectoine is mediated by an evolutionarily conserved ectoine hydroxylase. The Journal of biological chemistry 20071026
Hypoxia-inducible factor 1 (HIF-1) pathway. Science's STKE : signal transduction knowledge environment 20071009
Stereospecific enzymatic transformation of alpha-ketoglutarate to (2S,3R)-3-methyl glutamate during acidic lipopeptide biosynthesis. Journal of the American Chemical Society 20071003
Purification and characterization of the bifunctional uridylyltransferase and the signal transducing proteins GlnB and GlnK from Herbaspirillum seropedicae. Protein expression and purification 20071001
Effects of ornithine alpha-ketoglutarate on protein metabolism in Yoshida sarcoma-bearing rats. Clinical nutrition (Edinburgh, Scotland) 20071001
L-2-hydroxyglutaric aciduria, a defect of metabolite repair. Journal of inherited metabolic disease 20071001
Effect of gamma-immunoglobulin on the asaccharolytic growth of Porphyromonas gingivalis. Journal of periodontal research 20071001
Novel insights into L-2-hydroxyglutaric aciduria: mass isotopomer studies reveal 2-oxoglutaric acid as the metabolic precursor of L-2-hydroxyglutaric acid. Journal of inherited metabolic disease 20071001
Biochemistry and bioenergetics of glutaryl-CoA dehydrogenase deficiency. Journal of inherited metabolic disease 20071001
The differential effects of superoxide anion, hydrogen peroxide and hydroxyl radical on cardiac mitochondrial oxidative phosphorylation. Free radical research 20071001
Alpha-ketoglutarate is the precursor of L-2-hydroxyglutarate. Journal of inherited metabolic disease 20071001
Three 2-oxoacid dehydrogenase operons in Haloferax volcanii: expression, deletion mutants and evolution. Microbiology (Reading, England) 20071001
Metabolic reconstruction and modeling of nitrogen fixation in Rhizobium etli. PLoS computational biology 20071001
Chemoenzymatic synthesis of glutamic acid analogues: substrate specificity and synthetic applications of branched chain aminotransferase from Escherichia coli. The Journal of organic chemistry 20070928
Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity. Biochemistry 20070925
Structural and functional properties of isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila reveal a cold-active enzyme with an unusual high thermal stability. Journal of molecular biology 20070907
Purification of branched-chain amino acid aminotransferase from Helicobacter pylori NCTC 11637. Amino acids 20070901
Glutamate production by Corynebacterium glutamicum: dependence on the oxoglutarate dehydrogenase inhibitor protein OdhI and protein kinase PknG. Applied microbiology and biotechnology 20070901
Mitochondrial protein lipoylation does not exclusively depend on the mtKAS pathway of de novo fatty acid synthesis in Arabidopsis. Plant physiology 20070901
Structural features of aluminium(III) complexes with bioligands in glutamate dehydrogenase reaction system--a review. Journal of inorganic biochemistry 20070901
Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins. Nature chemical biology 20070901
Ectopic expression of phosphoenolpyruvate carboxylase in Vicia narbonensis seeds: effects of improved nutrient status on seed maturation and transcriptional regulatory networks. The Plant journal : for cell and molecular biology 20070901
Terrequinone A biosynthesis through L-tryptophan oxidation, dimerization and bisprenylation. Nature chemical biology 20070901
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Peripheral tolerance and the qualitative characteristics of autoreactive T cell clones in primary biliary cirrhosis. Journal of immunology (Baltimore, Md. : 1950) 20070901
Offering surprises: TCA cycle regulation in Corynebacterium glutamicum. Trends in microbiology 20070901
The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins. Journal of structural and functional genomics 20070901
The daily timing of gene expression and physiology in mammals. Dialogues in clinical neuroscience 20070901
Expression and sub-cellular localization of human ABH family molecules. Journal of cellular and molecular medicine 20070901
Pathogenesis of Alzheimer's disease. Clinical interventions in aging 20070901
Crystal structure and biochemical properties of the D-arabinose dehydrogenase from Sulfolobus solfataricus. Journal of molecular biology 20070831
Zinc irreversibly damages major enzymes of energy production and antioxidant defense prior to mitochondrial permeability transition. The Journal of biological chemistry 20070817
Succinate modulation of H2O2 release at NADH:ubiquinone oxidoreductase (Complex I) in brain mitochondria. The Biochemical journal 20070815
Post-translational modifications of collagen upon BMP-induced osteoblast differentiation. Biochemical and biophysical research communications 20070803
Expanding the lysyl hydroxylase toolbox: new insights into the localization and activities of lysyl hydroxylase 3 (LH3). Journal of cellular physiology 20070801
Alpha-ketoglutarate stimulates procollagen production in cultured human dermal fibroblasts, and decreases UVB-induced wrinkle formation following topical application on the dorsal skin of hairless mice. Biological & pharmaceutical bulletin 20070801
Mechanisms and kinetics of chelating reaction between novel chitosan derivatives and Zn(II). Journal of hazardous materials 20070719
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. Nature 20070705
Preparation and properties of modified chitosan as potential matrix materials for drug sustained-release beads. International journal of biological macromolecules 20070701
Cl- -dependent upregulation of human organic anion transporters: different effects on transport kinetics between hOAT1 and hOAT3. American journal of physiology. Renal physiology 20070701
NAD-dependent isocitrate dehydrogenase mutants of Arabidopsis suggest the enzyme is not limiting for nitrogen assimilation. Plant physiology 20070701
Replacement of non-heme Fe(II) with Cu(II) in the alpha-ketoglutarate dependent DNA repair enzyme AlkB: spectroscopic characterization of the active site. Journal of inorganic biochemistry 20070701
Low intensity training decreases markers of oxidative stress in skeletal muscle of mdx mice. Free radical biology & medicine 20070701
The road to non-heme oxoferryls and beyond. Accounts of chemical research 20070701
Sequential measurement of aminotransferase activities by amperometric biosensors. Biosensors & bioelectronics 20070615
Antioxidant properties of Krebs cycle intermediates against malonate pro-oxidant activity in vitro: a comparative study using the colorimetric method and HPLC analysis to determine malondialdehyde in rat brain homogenates. Life sciences 20070613
Lysyl hydroxylase 2 is a specific telopeptide hydroxylase, while all three isoenzymes hydroxylate collagenous sequences. Matrix biology : journal of the International Society for Matrix Biology 20070601
The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes. Neurochemistry international 20070601
Proteome and immunome of the venom of the Thai cobra, Naja kaouthia. Toxicon : official journal of the International Society on Toxinology 20070601
Hypotonic swelling of salicylate-treated cochlear outer hair cells. Hearing research 20070601
Functional and structural role of amino acid residues in the odd-numbered transmembrane alpha-helices of the bovine mitochondrial oxoglutarate carrier. Journal of molecular biology 20070601
Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability. Neurochemistry international 20070601
Light-dependent assimilation of trans-cinnamate by Rhodobacter sphaeroides OU5. Current microbiology 20070601
Protective effect of dietary squalene supplementation on mitochondrial function in liver of aged rats. Prostaglandins, leukotrienes, and essential fatty acids 20070601
Gene expression profiles of Chlamydophila pneumoniae during the developmental cycle and iron depletion-mediated persistence. PLoS pathogens 20070601
Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia. The Yale journal of biology and medicine 20070601
Probing the iron-substrate orientation for taurine/alpha-ketoglutarate dioxygenase using deuterium electron spin echo envelope modulation spectroscopy. Biochemistry 20070522
Characterization of a lipoate-protein ligase A gene of rice (Oryza sativa L.). Gene 20070515
Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans. Biochemistry 20070508
Enhanced transaminase activity of a bifunctional L-aspartate 4-decarboxylase. Biochemical and biophysical research communications 20070504
Role of the H domain of the histidine kinase-like protein NifL in signal transmission. The Journal of biological chemistry 20070504
Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex. Journal of molecular biology 20070504
Recruitment of NADH shuttling in pressure-overloaded and hypertrophic rat hearts. American journal of physiology. Cell physiology 20070501
Physiology of the yeast Kluyveromyces marxianus during batch and chemostat cultures with glucose as the sole carbon source. FEMS yeast research 20070501
A fundamental dual regulatory role of citrate on the biosyntheses of thuringiensin and poly-beta-hydroxybutyrate in Bacillus thuringiensis YBT-032. Biotechnology letters 20070501
The post-translational phenotype of collagen synthesized by SAOS-2 osteosarcoma cells. Bone 20070501
Novel enzyme reactions related to the tricarboxylic acid cycle: phylogenetic/functional implications and biotechnological applications. Applied microbiology and biotechnology 20070501
Manganese speciation in human cerebrospinal fluid using CZE coupled to inductively coupled plasma MS. Electrophoresis 20070501
Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men. International journal of molecular medicine 20070501
The activity of adenylyltransferase in Rhodospirillum rubrum is only affected by alpha-ketoglutarate and unmodified PII proteins, but not by glutamine, in vitro. The FEBS journal 20070501
Identification of a novel PP2C-type mitochondrial phosphatase. Biochemical and biophysical research communications 20070427
Alteration of DMBA-induced oxidative stress by additive action of a modified indigenous preparation--Kalpaamruthaa. Chemico-biological interactions 20070425
Activation and coupling of the glutaminase and synthase reaction of glutamate synthase is mediated by E1013 of the ferredoxin-dependent enzyme, belonging to loop 4 of the synthase domain. Biochemistry 20070417
Repair of methyl lesions in DNA and RNA by oxidative demethylation. Neuroscience 20070414
How a single T cell receptor recognizes both self and foreign MHC. Cell 20070406
Structure-function analysis of glutamine synthetase adenylyltransferase (ATase, EC 2.7.7.49) of Escherichia coli. Biochemistry 20070403
Escherichia coli glutamine synthetase adenylyltransferase (ATase, EC 2.7.7.49): kinetic characterization of regulation by PII, PII-UMP, glutamine, and alpha-ketoglutarate. Biochemistry 20070403
Evidence for a higher glycolytic than oxidative metabolic activity in white matter of rat brain. Neurochemistry international 20070401
Exclusion of OGDH and BMP4 as candidate genes in two siblings with autosomal recessive DOOR syndrome. American journal of medical genetics. Part A 20070401
A gene duplication led to specialized gamma-aminobutyrate and beta-alanine aminotransferase in yeast. The FEBS journal 20070401
Interaction of Epe1 with the heterochromatin assembly pathway in Schizosaccharomyces pombe. Genetics 20070401
Effect of cadmium on chlorophyll biosynthesis and enzymes of nitrogen assimilation in greening maize leaf segments: role of 2-oxoglutarate. Indian journal of experimental biology 20070401
Oxalomalate affects the inducible nitric oxide synthase expression and activity. Life sciences 20070313
Tissue-specific changes in the hydroxylysine content and cross-links of collagens and alterations in fibril morphology in lysyl hydroxylase 1 knock-out mice. The Journal of biological chemistry 20070302
alpha-ketoglutaric semialdehyde dehydrogenase isozymes involved in metabolic pathways of D-glucarate, D-galactarate, and hydroxy-L-proline. Molecular and metabolic convergent evolution. The Journal of biological chemistry 20070302
Functional analysis of norcoclaurine synthase in Coptis japonica. The Journal of biological chemistry 20070302
Poly-beta-hydroxybutyrate accumulation in Nostoc muscorum: effects of metabolic inhibitors. Journal of plant physiology 20070301
Thermal stability and biochemical properties of isocitrate dehydrogenase from the thermoacidophilic archaeon Thermoplasma acidophilum. Extremophiles : life under extreme conditions 20070301
Differential effects of selenium compounds on glucose synthesis in rabbit kidney-cortex tubules and hepatocytes. In vitro and in vivo studies. Journal of inorganic biochemistry 20070301
Effect of ornithine alpha-ketoglutarate on glutamine pools in burn injury: evidence of component interaction. Intensive care medicine 20070301
Downregulation of organic anion transporters in rat kidney under ischemia/reperfusion-induced acute [corrected] renal failure. Kidney international 20070301
Erythropoietin after a century of research: younger than ever. European journal of haematology 20070301
Simultaneous measurement of D-serine dehydratase and d-amino acid oxidase activities by the detection of 2-oxo-acid formation with reverse-phase high-performance liquid chromatography. Analytical biochemistry 20070301
Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta. Nature genetics 20070301
Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one? Nature chemical biology 20070301
Enzymatic and metabolic evidence for a region specific mitochondrial dysfunction in brains of murine succinic semialdehyde dehydrogenase deficiency (Aldh5a1-/- mice). Neurochemistry international 20070301
Alanine aminotransferase catalyses the breakdown of alanine after hypoxia in Arabidopsis thaliana. The Plant journal : for cell and molecular biology 20070301
A statistical approach using L(25) orthogonal array method to study fermentative production of clavulanic acid by Streptomyces clavuligerus MTCC 1142. Applied biochemistry and biotechnology 20070301
Alpha-ketoglutarate decreases serum levels of C-terminal cross-linking telopeptide of type I collagen (CTX) in postmenopausal women with osteopenia: six-month study. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070301
Characterization of the 2-hydroxy-acid dehydrogenase McyI, encoded within the microcystin biosynthesis gene cluster of Microcystis aeruginosa PCC7806. The Journal of biological chemistry 20070216
Toward an improved understanding of the glutamate mutase system. Journal of the American Chemical Society 20070214
S-allylcysteine ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing cardiac mitochondrial and lysosomal enzymes. Life sciences 20070213
HIF and fumarate hydratase in renal cancer. British journal of cancer 20070212
Molecular mechanism of the regulation of Bacillus subtilis gltAB expression by GltC. Journal of molecular biology 20070202
Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates. The Journal of biological chemistry 20070202
Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids. Clinica chimica acta; international journal of clinical chemistry 20070201
Glutamine supplementation in the newborn infant. Seminars in fetal & neonatal medicine 20070201
Expression of cytosolic branched chain aminotransferase (BCATc) mRNA in the developing mouse brain. Gene expression patterns : GEP 20070201
Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3. Nature chemical biology 20070201
The most versatile of all reactive intermediates? Nature chemical biology 20070201
Folding and turnover of human iron regulatory protein 1 depend on its subcellular localization. The FEBS journal 20070201
Global gene expression analysis of glucose overflow metabolism in Escherichia coli and reduction of aerobic acetate formation. Applied microbiology and biotechnology 20070201
N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology. Progress in neurobiology 20070201
Effect of pre-treatment of alpha-ketoglutarate on cyanide-induced toxicity and alterations in various physiological variables in rodents. Biomedical and environmental sciences : BES 20070201
Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake. The EMBO journal 20070124
Development and validation of a liquid chromatographic method for the determination of hydroxymethylfurfural and alpha-ketoglutaric acid in human plasma. Analytica chimica acta 20070109
Adriamycin induced myocardial failure in rats: protective role of Centella asiatica. Molecular and cellular biochemistry 20070101
Regulation of mitochondrial NADP-isocitrate dehydrogenase in rat heart during ischemia. Molecular and cellular biochemistry 20070101
Lipoic acid as a novel treatment for Alzheimer's disease and related dementias. Pharmacology & therapeutics 20070101
Redistribution of carbon flux in Torulopsis glabrata by altering vitamin and calcium level. Metabolic engineering 20070101
Genomic structure and embryonic expression of zebrafish lysyl hydroxylase 1 and lysyl hydroxylase 2. Matrix biology : journal of the International Society for Matrix Biology 20070101
Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101
Tobacco isoenzyme 1 of NAD(H)-dependent glutamate dehydrogenase catabolizes glutamate in vivo. Plant physiology 20070101
Glutamine signalling in bacteria. Frontiers in bioscience : a journal and virtual library 20070101
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Characterization of Bacillus subtilis mutants with carbon source-independent glutamate biosynthesis. Journal of molecular microbiology and biotechnology 20070101
The proteomic profile of Fusobacterium nucleatum is regulated by growth pH. Microbiology (Reading, England) 20070101
Tetrahydrobiopterin availability in Parkinson's and Alzheimer's disease; potential pathogenic mechanisms. Neurochemical research 20070101
Integration of regulatory signals through involvement of multiple global regulators: control of the Escherichia coli gltBDF operon by Lrp, IHF, Crp, and ArgR. BMC microbiology 20070101
Identification of candidate methylation-responsive genes in ovarian cancer. Molecular cancer 20070101
Electrochemical regeneration of NADH using conductive vanadia-silica xerogels. Biotechnology progress 20070101
Fluxome analysis using GC-MS. Microbial cell factories 20070101
Branched chain keto-acids exert biphasic effects on alpha-ketoglutarate-stimulated respiration in intact rat liver mitochondria. Neurochemical research 20070101
Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress. Neurochemical research 20070101
Genome analysis of DNA repair genes in the alpha proteobacterium Caulobacter crescentus. BMC microbiology 20070101
Metabolic modeling of a mutualistic microbial community. Molecular systems biology 20070101
A network perspective on the topological importance of enzymes and their phylogenetic conservation. BMC bioinformatics 20070101
[Simultaneous determination of twenty-one organic acids in food by ion chromatography with eluent autogeneration]. Se pu = Chinese journal of chromatography 20070101
Growth control of the eukaryote cell: a systems biology study in yeast. Journal of biology 20070101
Biochemical assays for mitochondrial activity: assays of TCA cycle enzymes and PDHc. Methods in cell biology 20070101
Multilevel regulation of growth rate in yeast revealed using systems biology. Journal of biology 20070101
A search engine to identify pathway genes from expression data on multiple organisms. BMC systems biology 20070101
Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite. PloS one 20070101
Nitrogen regulation in bacteria and archaea. Annual review of microbiology 20070101
13CO2 as a universal metabolic tracer in isotopologue perturbation experiments. Phytochemistry 20070101
Brucella suis urease encoded by ure1 but not ure2 is necessary for intestinal infection of BALB/c mice. BMC microbiology 20070101
Glutamate in plants: metabolism, regulation, and signalling. Journal of experimental botany 20070101
Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis. Microbial cell factories 20070101
Observing metabolic functions at the genome scale. Genome biology 20070101
Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine. Research in microbiology 20070101
Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes. Genome biology 20070101
Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli. Molecular systems biology 20070101
An analysis of expression patterns of genes encoding proteins with catalytic activities. BMC genomics 20070101
Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases. Current medicinal chemistry 20070101
Comparative proteomics reveal characteristics of life-history transitions in a social insect. Proteome science 20070101
Expression profile of proteins involved in scar formation in the healing process of full-thickness excisional wounds in the porcine model. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101
Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. BMC infectious diseases 20070101
The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. PloS one 20070101
The primordial metabolism: an ancestral interconnection between leucine, arginine, and lysine biosynthesis. BMC evolutionary biology 20070101
Metabolic peculiarities of Aspergillus niger disclosed by comparative metabolic genomics. Genome biology 20070101
Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens. PloS one 20070101
Comparative proteome analysis of human epithelial ovarian cancer. Proteome science 20070101
Horizontal gene transfer in chromalveolates. BMC evolutionary biology 20070101
Cadmium triggers an integrated reprogramming of the metabolism of Synechocystis PCC6803, under the control of the Slr1738 regulator. BMC genomics 20070101
Host origin of plastid solute transporters in the first photosynthetic eukaryotes. Genome biology 20070101
Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons. BMC neuroscience 20070101
Fasting induces a biphasic adaptive metabolic response in murine small intestine. BMC genomics 20070101
Visualizing regulatory interactions in metabolic networks. BMC biology 20070101
Effects of iron loading on muscle: genome-wide mRNA expression profiling in the mouse. BMC genomics 20070101
Long-term abnormalities in brain glucose/energy metabolism after inhibition of the neuronal insulin receptor: implication of tau-protein. Journal of neural transmission. Supplementum 20070101
[Characteristic metabolic disturbances in the rat tissues caused by long-term use of alcohol]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101
UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures. BMC plant biology 20070101
Preventive effect of naringin on cardiac mitochondrial enzymes during isoproterenol-induced myocardial infarction in rats: a transmission electron microscopic study. Journal of biochemical and molecular toxicology 20070101
The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily. BMC biochemistry 20070101
Characterization of ankyrin repeat-containing proteins as substrates of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible transcription factor. Methods in enzymology 20070101
Rapid changes in gene expression dynamics in response to superoxide reveal SoxRS-dependent and independent transcriptional networks. PloS one 20070101
Promoter analysis of intestinal genes induced during iron-deprivation reveals enrichment of conserved SP1-like binding sites. BMC genomics 20070101
Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana. BMC systems biology 20070101
[Effect of cadmium sulphate on the metabolism of carbohydrates in organism of rats of different ages]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101
Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis. BMC bioinformatics 20070101
The oncoprotein H-RasV12 increases mitochondrial metabolism. Molecular cancer 20070101
Sucrose phosphate synthase activity and the co-ordination of carbon partitioning during sucrose and amino acid accumulation in desiccation-tolerant leaf material of the C4 resurrection plant Sporobolus stapfianus during dehydration. Journal of experimental botany 20070101
Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice. BMC genomics 20070101
The plasticizer butyl benzyl phthalate induces genomic changes in rat mammary gland after neonatal/prepubertal exposure. BMC genomics 20070101
Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. Theoretical biology & medical modelling 20070101
Gene expression profile in obesity and type 2 diabetes mellitus. Lipids in health and disease 20070101
Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions. Critical care (London, England) 20070101
Microarray analysis of iron deficiency chlorosis in near-isogenic soybean lines. BMC genomics 20070101
The complete genome sequence and analysis of the epsilonproteobacterium Arcobacter butzleri. PloS one 20070101
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[Decrease of phosphate concentration in the medium by Brevibacterium casei cells]. Mikrobiologiia 20070101
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[L-2-hydroxyglutaric aciduria, an error of metabolism]. Bulletin et memoires de l'Academie royale de medecine de Belgique 20070101
Attenuation of mitochondrial injury by L-arginine preconditioning of the liver. BioFactors (Oxford, England) 20070101
Increased endogenous nitric oxide release by iron chelation and purinergic activation in the rat carotid body. The open biochemistry journal 20070101
Driving parts of Krebs cycle in reverse through mineral photochemistry. Journal of the American Chemical Society 20061220
Mutation-induced metabolite pool alterations in Corynebacterium glutamicum: towards the identification of nitrogen control signals. Journal of biotechnology 20061201
Aging: a shift from redox regulation to oxidative damage. Free radical research 20061201
The genome of deep-sea vent chemolithoautotroph Thiomicrospira crunogena XCL-2. PLoS biology 20061201
The human malaria parasite Plasmodium falciparum expresses an atypical N-terminally extended pyrophosphokinase with specificity for thiamine. Biological chemistry 20061201
Interaction of the membrane-bound GlnK-AmtB complex with the master regulator of nitrogen metabolism TnrA in Bacillus subtilis. The Journal of biological chemistry 20061117
Oxo-4-methylpentanoic acid directs the metabolism of GABA into the Krebs cycle in rat pancreatic islets. The Biochemical journal 20061115
Biochemical and functional modulation of the cartilage collagen network by IGF1, TGFbeta2 and FGF2. Osteoarthritis and cartilage 20061101
2-Oxoglutarate downregulates expression of vascular endothelial growth factor and erythropoietin through decreasing hypoxia-inducible factor-1alpha and inhibits angiogenesis. Journal of cellular physiology 20061101
Functional diversity of lysyl hydroxylase 2 in collagen synthesis of human dermal fibroblasts. Experimental cell research 20061101
Glutamate:glyoxylate aminotransferase modulates amino acid content during photorespiration. Plant physiology 20061101
Dactylorhin B reduces toxic effects of beta-amyloid fragment (25-35) on neuron cells and isolated rat brain mitochondria. Naunyn-Schmiedeberg's archives of pharmacology 20061101
A novel oxalosuccinate-forming enzyme involved in the reductive carboxylation of 2-oxoglutarate in Hydrogenobacter thermophilus TK-6. Molecular microbiology 20061101
Impact of the C-N status on the amino acid profile in tobacco source leaves. Plant, cell & environment 20061101
[Gas liquid chromatographic determination of tricarbonic cycle acids in human plasma]. Klinicheskaia laboratornaia diagnostika 20061101
Mitochondrial glutathione transport: physiological, pathological and toxicological implications. Chemico-biological interactions 20061027
Mitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolism. Chemico-biological interactions 20061027
Ferulic acid with ascorbic acid synergistically extenuates the mitochondrial dysfunction during beta-adrenergic catecholamine induced cardiotoxicity in rats. Chemico-biological interactions 20061027
Free radical scavenging activity of the marine mangrove Rhizophora apiculata bark extract with reference to naphthalene induced mitochondrial dysfunction. Chemico-biological interactions 20061027
Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier. The Journal of biological chemistry 20061020
CRTAP is required for prolyl 3- hydroxylation and mutations cause recessive osteogenesis imperfecta. Cell 20061020
Functional and structural role of amino acid residues in the even-numbered transmembrane alpha-helices of the bovine mitochondrial oxoglutarate carrier. Journal of molecular biology 20061013
In vitro analysis of the Escherichia coli AmtB-GlnK complex reveals a stoichiometric interaction and sensitivity to ATP and 2-oxoglutarate. The Journal of biological chemistry 20061006
First identification of a 2-ketoglutarate/isocitrate transport system in mammalian peroxisomes and its characterization. Biochemical and biophysical research communications 20061006
Direct evidence for a glutamate switch necessary for substrate recognition: crystal structures of lysine epsilon-aminotransferase (Rv3290c) from Mycobacterium tuberculosis H37Rv. Journal of molecular biology 20061006
Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae. Biochemistry 20061003
Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae. Biochemistry 20061003
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH). Proceedings of the National Academy of Sciences of the United States of America 20061003
Retrovirus producer cell line metabolism: implications on viral productivity. Applied microbiology and biotechnology 20061001
Activation of ERK1/2 pathway mediates oxidant-induced decreases in mitochondrial function in renal cells. American journal of physiology. Renal physiology 20061001
Evaluation of metabolic alteration in transgenic rice overexpressing dihydroflavonol-4-reductase. Annals of botany 20061001
Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models. Diabetologia 20061001
Restorative effect of Kalpaamruthaa, an indigenous preparation, on oxidative damage in mammary gland mitochondrial fraction in experimental mammary carcinoma. Molecular and cellular biochemistry 20061001
Metabolic normalization of alpha-ketoglutarate against N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. Fundamental & clinical pharmacology 20061001
The lysyl hydroxylase isoforms are widely expressed during mouse embryogenesis, but obtain tissue- and cell-specific patterns in the adult. Matrix biology : journal of the International Society for Matrix Biology 20061001
Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression. Clinical and experimental pharmacology & physiology 20061001
Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of the biosynthetic N-acetylornithine aminotransferases from Salmonella typhimurium and Escherichia coli. Acta crystallographica. Section F, Structural biology and crystallization communications 20061001
Abiotic stress generates ROS that signal expression of anionic glutamate dehydrogenases to form glutamate for proline synthesis in tobacco and grapevine. The Plant cell 20061001
Kinetic model of mitochondrial Krebs cycle: unraveling the mechanism of salicylate hepatotoxic effects. Journal of biological physics 20061001
A novel alpha-ketoglutaric semialdehyde dehydrogenase: evolutionary insight into an alternative pathway of bacterial L-arabinose metabolism. The Journal of biological chemistry 20060929
Identification and mRNA expression of Ogdh, QP-C, and two predicted genes in the postnatal mouse brain. Neuroscience letters 20060925
Identification of the missing links in prokaryotic pentose oxidation pathways: evidence for enzyme recruitment. The Journal of biological chemistry 20060915
Cytosolic branched chain aminotransferase (BCATc) mRNA is up-regulated in restricted brain areas of BDNF transgenic mice. Brain research 20060907
Preconditioning prevents loss in mitochondrial function and release of cytochrome c during prolonged cardiac ischemia/reperfusion. Archives of biochemistry and biophysics 20060901
Ammonia permeability of the aquaglyceroporins from Plasmodium falciparum, Toxoplasma gondii and Trypansoma brucei. Molecular microbiology 20060901
Pharmacokinetics, safety, and effects on exercise performance of L-arginine alpha-ketoglutarate in trained adult men. Nutrition (Burbank, Los Angeles County, Calif.) 20060901
A metabonomics study of the hepatotoxicants galactosamine, methylene dianiline and clofibrate in rats. Basic & clinical pharmacology & toxicology 20060901
Characterization of salicylate uptake across the basolateral membrane of the malpighian tubules of Drosophila melanogaster. Journal of insect physiology 20060901
Biosynthesis of the (2S,3R)-3-methyl glutamate residue of nonribosomal lipopeptides. Journal of the American Chemical Society 20060830
Study of a novel indolin-2-ketone compound Z24 induced hepatotoxicity by NMR-spectroscopy-based metabonomics of rat urine, blood plasma, and liver extracts. Toxicology and applied pharmacology 20060815
Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins. The Biochemical journal 20060815
A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 alpha. Journal of cell science 20060815
Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer. British journal of cancer 20060807
Modifications of the lipoamide-containing mitochondrial subproteome in a yeast mutant defective in cysteine desulfurase. Molecular & cellular proteomics : MCP 20060801
RS-alpha-lipoic acid protects cholinergic cells against sodium nitroprusside and amyloid-beta neurotoxicity through restoration of acetyl-CoA level. Journal of neurochemistry 20060801
Ammonium chloride and alpha-ketoglutaric acid increase glutamine availability in the early phase of induced acute metabolic acidosis. Acta anaesthesiologica Scandinavica 20060801
Nitrogen source and the retrograde signalling pathway affect detection, not generation, of the [URE3] prion. Yeast (Chichester, England) 20060801
Studying the signaling role of 2-oxoglutaric acid using analogs that mimic the ketone and ketal forms of 2-oxoglutaric acid. Chemistry & biology 20060801
Effect of maternal dexamethasone and alpha-ketoglutarate administration on skeletal development during the last three weeks of prenatal life in pigs. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20060801
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage. The EMBO journal 20060726
Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells. Biochemistry 20060725
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. Nature 20060720
Inactivation of GABA transaminase by 4-acryloylphenol. Bioorganic & medicinal chemistry letters 20060715
The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases. Cardiovascular research 20060715
Ornithine alpha-ketoglutarate increases mineralization and mechanical properties of tibia in turkeys. Bone 20060701
The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates. The Biochemical journal 20060701
On-line optimization of glutamate production based on balanced metabolic control by RQ. Bioprocess and biosystems engineering 20060701
Metabolic pathway analysis for rational design of L-methionine production by Escherichia coli and Corynebacterium glutamicum. Metabolic engineering 20060701
The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima. The FEBS journal 20060701
A shortcut to mitochondrial signaling and pathology: a commentary on 'Nonenzymatic formation of succinate in mitochondria under oxidative stress'. Free radical biology & medicine 20060701
Nonezymatic formation of succinate in mitochondria under oxidative stress. Free radical biology & medicine 20060701
Interaction network in cyanobacterial nitrogen regulation: PipX, a protein that interacts in a 2-oxoglutarate dependent manner with PII and NtcA. Molecular microbiology 20060701
Purification and characterization of two enantioselective alpha-ketoglutarate-dependent dioxygenases, RdpA and SdpA, from Sphingomonas herbicidovorans MH. Applied and environmental microbiology 20060701
Cytosolic heat shock proteins and heme oxygenase-1 are preferentially induced in response to specific and localized intramitochondrial damage by tetrafluoroethylcysteine. Biochemical pharmacology 20060628
Free radical-mediated neurotoxicity may be caused by inhibition of mitochondrial dehydrogenases in vitro and in vivo. Neuroscience 20060619
Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid. FEBS letters 20060612
Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes. The Journal of biological chemistry 20060609
Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. The Journal of biological chemistry 20060602
Changes in oxygen consumption and respiratory enzymes as stress indicators in an estuarine edible crab Scylla serrata exposed to naphthalene. Chemosphere 20060601
Intraduodenal infusion of alpha-ketoglutarate decreases whole body energy expenditure in growing pigs. Clinical nutrition (Edinburgh, Scotland) 20060601
Activities of membrane bound phosphatases, transaminases and mitochondrial enzymes in white spot syndrome virus infected tissues of Fenneropenaeus indicus. Virus research 20060601
Lysyl hydroxylase 3 (LH3) modifies proteins in the extracellular space, a novel mechanism for matrix remodeling. Journal of cellular physiology 20060601
Proteome analysis of Halobacterium sp. NRC-1 facilitated by the biomodule analysis tool BMSorter. Molecular & cellular proteomics : MCP 20060601
Combined transcript and metabolite profiling of Arabidopsis leaves reveals fundamental effects of the thiol-disulfide status on plant metabolism. Plant physiology 20060601
Acrolein is a mitochondrial toxin: effects on respiratory function and enzyme activities in isolated rat liver mitochondria. Mitochondrion 20060601
The myotomal diwanka (lh3) glycosyltransferase and type XVIII collagen are critical for motor growth cone migration. Neuron 20060601
Structural basis for the enantiospecificities of R- and S-specific phenoxypropionate/alpha-ketoglutarate dioxygenases. Protein science : a publication of the Protein Society 20060601
Peroxynitrite as an alternative donor of oxygen in HIF-1alpha proline hydroxylation under low oxygen availability. Free radical research 20060601
Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 A resolution. Acta crystallographica. Section F, Structural biology and crystallization communications 20060601
Relative contribution of OAT1 and OAT3 transport activities in isolated perfused rabbit renal proximal tubules. Biochimica et biophysica acta 20060601
Molecular cloning and characterization of a large subunit of Salmonella typhimurium glutamate synthase (GOGAT) gene in Escherichia coli. Journal of microbiology (Seoul, Korea) 20060601
Diffusion-Weighted MRI in Recurrent Wernicke's Encephalopathy: a Remarkable Cerebellar Lesion. Journal of clinical neurology (Seoul, Korea) 20060601
Influence of peptide supply and cosubstrates on phenylalanine metabolism of Lactobacillus sanfranciscensis DSM20451(T) and Lactobacillus plantarum TMW1.468. Journal of agricultural and food chemistry 20060531
Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlH, a non-heme iron dioxygenase of Streptomyces avermitilis. Journal of the American Chemical Society 20060524
Structural insights into histone demethylation by JMJD2 family members. Cell 20060519
13C magnetic resonance spectroscopy studies of alterations in glutamate neurotransmission. Biological psychiatry 20060515
Corynebacterial protein kinase G controls 2-oxoglutarate dehydrogenase activity via the phosphorylation status of the OdhI protein. The Journal of biological chemistry 20060505
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. Cell 20060505
Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron. Biochimie 20060501
D-2-hydroxyglutaric aciduria in three patients with proven SSADH deficiency: genetic coincidence or a related biochemical epiphenomenon? Molecular genetics and metabolism 20060501
Development of a kinetic metabolic model: application to Catharanthus roseus hairy root. Bioprocess and biosystems engineering 20060501
Variation of milk citrate with stage of lactation and de novo fatty acid synthesis in dairy cows. Journal of dairy science 20060501
Gene expression of Corynebacterium glutamicum in response to the conditions inducing glutamate overproduction. Letters in applied microbiology 20060501
Expression of cytosolic NADP+-dependent isocitrate dehydrogenase in bovine mammary epithelium: Modulation by regulators of differentiation and metabolic effectors. Experimental biology and medicine (Maywood, N.J.) 20060501
Metabolic characteristics of recombinant Chinese hamster ovary cells expressing glutamine synthetase in presence and absence of glutamine. Cytotechnology 20060501
Epimerization and desaturation by carbapenem synthase (CarC). A hybrid DFT study. Journal of computational chemistry 20060430
Hypobaric hypoxia affects endogenous levels of alpha-keto acids in murine heart ventricles. Biochemical and biophysical research communications 20060414
Functional characterization of Na+ -coupled citrate transporter NaC2/NaCT expressed in primary cultures of neurons from mouse cerebral cortex. Brain research 20060407
Cardiotoxicity of copper-based antineoplastic drugs casiopeinas is related to inhibition of energy metabolism. Toxicology and applied pharmacology 20060401
Gene cloning, heterologous overexpression and optimized refolding of the NAD-glutamate dehydrogenase from Haloferax mediterranei. Extremophiles : life under extreme conditions 20060401
Substrate-free structure of a monomeric NADP isocitrate dehydrogenase: an open conformation phylogenetic relationship of isocitrate dehydrogenase. Proteins 20060401
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins. Journal of inorganic biochemistry 20060401
Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins. Journal of inorganic biochemistry 20060401
Theoretical analysis of carbon-13 magnetization transfer for in vivo exchange between alpha-ketoglutarate and glutamate. NMR in biomedicine 20060401
Control of carbon flux through enzymes of central and intermediary metabolism during growth of Escherichia coli on acetate. Current opinion in microbiology 20060401
Pathways of carbon assimilation and ammonia oxidation suggested by environmental genomic analyses of marine Crenarchaeota. PLoS biology 20060401
The effect of aging on anaerobic and aerobic enzyme activities in human skeletal muscle. The journals of gerontology. Series A, Biological sciences and medical sciences 20060401
Quantum chemical modeling of reaction mechanism for 2-oxoglutarate dependent enzymes: effect of substitution of iron by nickel and cobalt. The journal of physical chemistry. A 20060330
Effect of lpdA gene knockout on the metabolism in Escherichia coli based on enzyme activities, intracellular metabolite concentrations and metabolic flux analysis by 13C-labeling experiments. Journal of biotechnology 20060323
Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis. Nature 20060316
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines. British journal of cancer 20060313
Glucose inhibits GABA release by pancreatic beta-cells through an increase in GABA shunt activity. American journal of physiology. Endocrinology and metabolism 20060301
Modulation of expression of rat mitochondrial 2-oxoglutarate carrier in NRK-52E cells alters mitochondrial transport and accumulation of glutathione and susceptibility to chemically induced apoptosis. The Journal of pharmacology and experimental therapeutics 20060301
Control of the synthesis and subcellular targeting of the two GDH genes products in leaves and stems of Nicotiana plumbaginifolia and Arabidopsis thaliana. Plant & cell physiology 20060301
Salt stress adaptation of Bacillus subtilis: a physiological proteomics approach. Proteomics 20060301
Metabolomic and bioinformatic analyses in asphyxiated neonates. Clinical biochemistry 20060301
A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD. Molecular microbiology 20060301
Levetiracetam: antiepileptic properties and protective effects on mitochondrial dysfunction in experimental status epilepticus. Epilepsia 20060301
A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and its derivatives. Evidence-based complementary and alternative medicine : eCAM 20060301
Cerebral metabolism in brains of rats infected with neuropathogenic murine leukemia viruses. The Journal of veterinary medical science 20060301
Analysis of ingested material and urine by GC-MS and 1H NMR spectroscopy: poisoning of an adult with adulterated soda. Journal of analytical toxicology 20060301
Vitamins in aging, health, and longevity. Clinical interventions in aging 20060301
Negative mode sheathless capillary electrophoresis electrospray ionization-mass spectrometry for metabolite analysis of prokaryotes. Journal of chromatography. A 20060217
Histone demethylation by a family of JmjC domain-containing proteins. Nature 20060216
Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB. Nature 20060216
Inhibitors of the alpha-ketoglutarate dehydrogenase complex alter [1-13C]glucose and [U-13C]glutamate metabolism in cerebellar granule neurons. Journal of neuroscience research 20060215
Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes. Journal of cell science 20060215
Cloning, expression, and characterization of bacterial L-arabinose 1-dehydrogenase involved in an alternative pathway of L-arabinose metabolism. The Journal of biological chemistry 20060203
Accumulation of nonesterified fatty acids causes the sustained energetic deficit in kidney proximal tubules after hypoxia-reoxygenation. American journal of physiology. Renal physiology 20060201
Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters. Pflugers Archiv : European journal of physiology 20060201
Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. Bioorganic & medicinal chemistry letters 20060201
Biochemical characterization of the glutamate transport in Trypanosoma cruzi. International journal for parasitology 20060201
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco. Plant physiology 20060201
Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme. The FEBS journal 20060201
Regulation of 2-oxoglutarate metabolism in rat liver by NADP-isocitrate dehydrogenase and aspartate aminotransferase. Biochemistry. Biokhimiia 20060201
D-2-Hydroxyglutaric aciduria: unravelling the biochemical pathway and the genetic defect. Journal of inherited metabolic disease 20060201
Effect of alpha-ketoglutarate on cyanide-induced biochemical alterations in rat brain and liver. Biomedical and environmental sciences : BES 20060201
Preferential energy- and potential-dependent accumulation of cisplatin-gutathione complexes in human cancer cell lines (GLC4 and K562): A likely role of mitochondria. Journal of bioenergetics and biomembranes 20060201
Cloning and characterization of a flavanone 3-hydroxylase gene from Ginkgo biloba. Bioscience reports 20060201
Identification and kinetic characterization of HtDTC, the mitochondrial dicarboxylate-tricarboxylate carrier of Jerusalem artichoke tubers. Journal of bioenergetics and biomembranes 20060201
Purifications and characterizations of a ferredoxin and its related 2-oxoacid:ferredoxin oxidoreductase from the hyperthermophilic archaeon, Sulfolobus solfataricus P1. Journal of biochemistry and molecular biology 20060131
Modulation of TCA cycle enzymes and electron transport chain systems in experimental lung cancer. Life sciences 20060125
Cellular mitochondrial heterogeneity in cultured astrocytes as demonstrated by immunogold labeling of alpha-ketoglutarate dehydrogenase. Glia 20060115
Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice. Mechanisms of ageing and development 20060101
Functional analysis through site-directed mutations and phylogeny of the Candida albicans LYS1-encoded saccharopine dehydrogenase. Molecular genetics and genomics : MGG 20060101
Self-hydroxylation of taurine/alpha-ketoglutarate dioxygenase: evidence for more than one oxygen activation mechanism. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20060101
The RpoS-mediated regulation of isocitrate dehydrogenase gene expression in Escherichia coli. Current microbiology 20060101
Antisense repression reveals a crucial role of the plastidic 2-oxoglutarate/malate translocator DiT1 at the interface between carbon and nitrogen metabolism. The Plant journal : for cell and molecular biology 20060101
Redirecting carbon flux in Torulopsis glabrata from pyruvate to alpha-ketoglutaric acid by changing metabolic co-factors. Biotechnology letters 20060101
Heterocyst differentiation and pattern formation in cyanobacteria: a chorus of signals. Molecular microbiology 20060101
Excess casein in the diet is not the unique cause of low-grade metabolic acidosis: role of a deficit in potassium citrate in a rat model. Annals of nutrition & metabolism 20060101
Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae. FEMS yeast research 20060101
GPNN: power studies and applications of a neural network method for detecting gene-gene interactions in studies of human disease. BMC bioinformatics 20060101
sucAB and sucCD are mutually essential genes in Escherichia coli. FEMS microbiology letters 20060101
Release of Ca2+ and Mg2+ from yeast mitochondria is stimulated by increased ionic strength. BMC biochemistry 20060101
A novel low molecular weight alanine aminotransferase from fasted rat liver. Biochemistry. Biokhimiia 20060101
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms. BMC bioinformatics 20060101
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes. BMC bioinformatics 20060101
[Metabolism of recombinant CHO-GS cell reducing of toxic effect of ammonia]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060101
[Stimulatory effects of some amino acids on glycerol production by Candida glycerinogenes]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060101
Alpha-ketoglutarate modulates the circadian patterns of lipid peroxidation and antioxidant status during N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. Journal of medicinal food 20060101
Global gene expression analyses of hematopoietic stem cell-like cell lines with inducible Lhx2 expression. BMC genomics 20060101
Mining gene expression data by interpreting principal components. BMC bioinformatics 20060101
How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome. Lipids in health and disease 20060101
N-acetylaspartate as a reservoir for glutamate. Medical hypotheses 20060101
Association of PLOD1 polymorphisms with bone mineral density in a population-based study of women from the UK. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20060101
Direct removal of alkylation damage from DNA by AlkB and related DNA dioxygenases. Methods in enzymology 20060101
Redox stress is not essential for the pseudo-hypoxic phenotype of succinate dehydrogenase deficient cells. Biochimica et biophysica acta 20060101
Clustering of Pseudomonas aeruginosa transcriptomes from planktonic cultures, developing and mature biofilms reveals distinct expression profiles. BMC genomics 20060101
MANET: tracing evolution of protein architecture in metabolic networks. BMC bioinformatics 20060101
[Correlation between succinate-dependent Ca2+ accumulation and transamination in the heart and the liver mitochondria of experimental animals]. Biomeditsinskaia khimiia 20060101
Aluminum toxicity elicits a dysfunctional TCA cycle and succinate accumulation in hepatocytes. Journal of biochemical and molecular toxicology 20060101
[The influence of the fluorine-containing activators of mitochondrial adenosine triphosphate sensitive potassium channels on the oxidative phosphorilation]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101
Hierarchical modularity of nested bow-ties in metabolic networks. BMC bioinformatics 20060101
Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p)ppGpp synthase. BMC genomics 20060101
Integration of metabolome data with metabolic networks reveals reporter reactions. Molecular systems biology 20060101
Global gene expression of Prochlorococcus ecotypes in response to changes in nitrogen availability. Molecular systems biology 20060101
[Subcellular localization, purification, and various catalitic properties of aspartate aminotransferase from Spirodela polyrhiza]. Izvestiia Akademii nauk. Seriia biologicheskaia 20060101
Comparative proteomic analysis of high cell density cultivations with two recombinant Bacillus megaterium strains for the production of a heterologous dextransucrase. Proteome science 20060101
Circulating immune complexes and trace elements (Copper, Iron and Selenium) as markers in oral precancer and cancer : a randomised, controlled clinical trial. Head & face medicine 20060101
Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal. Arthritis research & therapy 20060101
Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics. Journal of biomedicine & biotechnology 20060101
The creatine kinase/creatine connection to Alzheimer's disease: CK-inactivation, APP-CK complexes and focal creatine deposits. Journal of biomedicine & biotechnology 20060101
Effects of the presence of ColE1 plasmid DNA in Escherichia coli on the host cell metabolism. Microbial cell factories 20060101
A computational analysis of the three isoforms of glutamate dehydrogenase reveals structural features of the isoform EC 1.4.1.4 supporting a key role in ammonium assimilation by plants. Biology direct 20060101
[Catalytic properties of 6-phosphogluconate dehydrogenase from rat liver in normal state and during toxic hepatitis]. Biomeditsinskaia khimiia 20060101
A low protein diet increases the hypoxic tolerance in Drosophila. PloS one 20060101
Structure of a conserved hypothetical protein SA1388 from S. aureus reveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center. BMC structural biology 20060101
[Correction of mitochondrial respiration processes in rats with different resistance to hypoxia under stress by modulators of ATP-sensitive potassium channels]. Biomeditsinskaia khimiia 20060101
Sodium fluoroacetate poisoning. Toxicological reviews 20060101
The oxygen sensing signal cascade under the influence of reactive oxygen species. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20051229
Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20051229
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. The Journal of biological chemistry 20051223
A continuous spectrophotometric assay method for peptidylarginine deiminase type 4 activity. Analytical biochemistry 20051215
Signalling hypoxia by HIF hydroxylases. Biochemical and biophysical research communications 20051209
Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease. The Journal of biological chemistry 20051209
Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor. Oncogene 20051208
White biotechnology for green chemistry: fermentative 2-oxocarboxylic acids as novel building blocks for subsequent chemical syntheses. Journal of industrial microbiology & biotechnology 20051201
Pyruvate protects glucose-deprived Müller cells from nitric oxide-induced oxidative stress by radical scavenging. Glia 20051201
In vivo carbon-13 magnetization transfer effect. Detection of aspartate aminotransferase reaction. Magnetic resonance in medicine 20051201
Effect of aromatic ring-containing drugs on carnitine biosynthesis in rats with special regard to p-aminomethylbenzoic acid. Metabolism: clinical and experimental 20051201
Electron cryotomography of the E. coli pyruvate and 2-oxoglutarate dehydrogenase complexes. Structure (London, England : 1993) 20051201
alpha-Ketoglutarate (AKG) absorption from pig intestine and plasma pharmacokinetics. Journal of animal physiology and animal nutrition 20051201
Enzyme inhibition assay for pyruvate dehydrogenase complex: clinical utility for the diagnosis of primary biliary cirrhosis. World journal of gastroenterology 20051121
Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. The Journal of biological chemistry 20051104
Alterations in neutrophil (PMN) free intracellular alpha-keto acid profiles and immune functions induced by L-alanyl-L-glutamine, arginine or taurine. Amino acids 20051101
Mitochondrial succinate is instrumental for HIF1alpha nuclear translocation in SDHA-mutant fibroblasts under normoxic conditions. Human molecular genetics 20051101
Effects of glucose limitation on biomass and spiramycin production by Streptomyces ambofaciens. Bioprocess and biosystems engineering 20051101
Plasmodium falciparum possesses organelle-specific alpha-keto acid dehydrogenase complexes and lipoylation pathways. Biochemical Society transactions 20051101
Determinants of substrate specificity in omega-aminotransferases. The Journal of biological chemistry 20051028
Identification of PamA as a PII-binding membrane protein important in nitrogen-related and sugar-catabolic gene expression in Synechocystis sp. PCC 6803. The Journal of biological chemistry 20051014
Efficacy of levo carnitine and alpha lipoic acid in ameliorating the decline in mitochondrial enzymes during aging. Clinical nutrition (Edinburgh, Scotland) 20051001
Differential requirements of calcium for oxoglutarate dehydrogenase and mitochondrial nitric-oxide synthase under hypoxia: impact on the regulation of mitochondrial oxygen consumption. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20051001
Lysine is catabolized to 2-aminoadipic acid in Penicillium chrysogenum by an omega-aminotransferase and to saccharopine by a lysine 2-ketoglutarate reductase. Characterization of the omega-aminotransferase. Molecular genetics and genomics : MGG 20051001
Localization of NAD-isocitrate dehydrogenase and glutamate dehydrogenase in rice roots: candidates for providing carbon skeletons to NADH-glutamate synthase. Plant & cell physiology 20051001
Interleukin 4 and prolonged hypoxia induce a higher gene expression of lysyl hydroxylase 2 and an altered cross-link pattern: important pathogenetic steps in early and late stage of systemic scleroderma? Matrix biology : journal of the International Society for Matrix Biology 20051001
Antioxidant effect of Sargassum polycystum (Phaeophyceae) against acetaminophen induced changes in hepatic mitochondrial enzymes during toxic hepatitis. Chemosphere 20051001
Molecular properties and enhancement of thermostability by random mutagenesis of glutamate dehydrogenase from Bacillus subtilis. Bioscience, biotechnology, and biochemistry 20051001
Resonance assignments of Escherichia coli AlkB: a key 2-oxoglutarate and Fe(II) dependent dioxygenase of the adaptive DNA-repair response. Journal of biomolecular NMR 20051001
Modification of thiamine pyrophosphate dependent enzyme activity by oxythiamine in Saccharomyces cerevisiae cells. Canadian journal of microbiology 20051001
Effects of alpha-ketoglutarate on bone homeostasis and plasma amino acids in turkeys. Poultry science 20051001
Dual effect of pyruvate in isolated nerve terminals: generation of reactive oxygen species and protection of aconitase. Neurochemical research 20051001
Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate. Molecular bioSystems 20051001
Structural and functional changes in heart mitochondria from sucrose-fed hypertriglyceridemic rats. Biochimica et biophysica acta 20050930
Incorporation of oxygen into the succinate co-product of iron(II) and 2-oxoglutarate dependent oxygenases from bacteria, plants and humans. FEBS letters 20050926
Effect of sub-acute oral cyanide administration in rats: protective efficacy of alpha-ketoglutarate and sodium thiosulfate. Chemico-biological interactions 20050910
Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. I. Kinetic studies. The Journal of biological chemistry 20050909
Structural and mechanistic studies on anthocyanidin synthase catalysed oxidation of flavanone substrates: the effect of C-2 stereochemistry on product selectivity and mechanism. Organic & biomolecular chemistry 20050907
Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast. The Journal of biological chemistry 20050902
Functional analysis of TMLH variants and definition of domains required for catalytic activity and mitochondrial targeting. Journal of cellular physiology 20050901
Modulation of higher-plant NAD(H)-dependent glutamate dehydrogenase activity in transgenic tobacco via alteration of beta subunit levels. Planta 20050901
Effect of L-carnitine on acetyl-CoA content and activity of blood platelets in healthy and diabetic persons. Clinical chemistry 20050901
Evidence for carbon flux shortage and strong carbon/nitrogen interactions in pea nodules at early stages of water stress. Journal of experimental botany 20050901
Mitochondria-driven changes in leaf NAD status exert a crucial influence on the control of nitrate assimilation and the integration of carbon and nitrogen metabolism. Plant physiology 20050901
Tubulointerstitial nephritis and Fanconi syndrome in primary biliary cirrhosis. American journal of kidney diseases : the official journal of the National Kidney Foundation 20050901
Lipopolysaccharide induces cell death in cultured porcine myenteric neurons. Digestive diseases and sciences 20050901
Alcoholic stem extract of Coscinium fenestratum regulates carbohydrate metabolism and improves antioxidant status in streptozotocin-nicotinamide induced diabetic rats. Evidence-based complementary and alternative medicine : eCAM 20050901
Free CoA-mediated regulation of intermediary and central metabolism: an hypothesis which accounts for the excretion of alpha-ketoglutarate during aerobic growth of Escherichia coli on acetate. Research in microbiology 20050901
Altering the substrate specificity of glutamate dehydrogenase from Bacillus subtilis by site-directed mutagenesis. Bioscience, biotechnology, and biochemistry 20050901
Biochemical characterisation of some non fermenting, non arginine hydrolysing mycoplasmas of ruminants. Veterinary microbiology 20050810
Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells. Biochemistry 20050809
The N-terminal cleavable extension of plant carrier proteins is responsible for efficient insertion into the inner mitochondrial membrane. Journal of molecular biology 20050805
Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice. American journal of physiology. Endocrinology and metabolism 20050801
CaAlaAT1 catalyzes the alanine: 2-oxoglutarate aminotransferase reaction during the resistance response against Tobacco mosaic virus in hot pepper. Planta 20050801
Nrf2 activation involves an oxidative-stress independent pathway in tetrafluoroethylcysteine-induced cytotoxicity. Toxicological sciences : an official journal of the Society of Toxicology 20050801
Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801
Multi-target antimicrobial actions of zinc against oral anaerobes. Archives of oral biology 20050801
Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. Molecular microbiology 20050801
Assays for mechanistic investigations of protein/histone acetyltransferases. Methods (San Diego, Calif.) 20050801
Thiamine-responsive congenital lactic acidosis: clinical and biochemical studies. Pediatric neurology 20050801
Ornithine alpha-ketoglutarate metabolism in the healthy rat in the postabsorptive state. Metabolism: clinical and experimental 20050801
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. Cancer cell 20050801
Effect of potassium salts in rats adapted to an acidogenic high-sulfur amino acid diet. The British journal of nutrition 20050801
Gibberellin 2-oxidases from seedlings of adzuki bean (Vigna angularis) show high gibberellin-binding activity in the presence of 2-oxoglutarate and Co2+. Bioscience, biotechnology, and biochemistry 20050801
Similarities and differences between the characteristics of gibberellin-binding protein and gibberellin 2-oxidases in adzuki bean (Vigna angularis) seedlings. Bioscience, biotechnology, and biochemistry 20050801
A global survey of gene regulation during cold acclimation in Arabidopsis thaliana. PLoS genetics 20050801
Disorders of pyruvate metabolism and the tricarboxylic acid cycle. Molecular genetics and metabolism 20050801
Therapeutic effect of tamoxifen and energy-modulating vitamins on carbohydrate-metabolizing enzymes in breast cancer. Cancer chemotherapy and pharmacology 20050701
Mg2+-malate co-transport, a mechanism for Na+-independent Mg2+ transport in neurons of the leech Hirudo medicinalis. Journal of neurophysiology 20050701
Differential expression of procollagen lysine 2-oxoglutarate 5-deoxygenase and matrix metalloproteinase isoforms in hypothyroid rat ovary and disintegration of extracellular matrix. Endocrinology 20050701
Cerebral metabolic disturbances in the brain during acute liver failure: from hyperammonemia to energy failure and proteolysis. Neurochemistry international 20050701
A combined (1)H NMR and HPLC-MS-based metabonomic study of urine from obese (fa/fa) Zucker and normal Wistar-derived rats. Journal of pharmaceutical and biomedical analysis 20050701
Zinc complexes with cyclic derivatives of alpha-ketoglutaric acid thiosemicarbazone: Synthesis, X-ray structures and DNA interactions. Journal of inorganic biochemistry 20050701
Convergent evolution of hydroxylation mechanisms in the fungal kingdom: molybdenum cofactor-independent hydroxylation of xanthine via alpha-ketoglutarate-dependent dioxygenases. Molecular microbiology 20050701
Identification of differentially expressed genes in hepatic HepG2 cells treated with acetaminophen using suppression subtractive hybridization. Biological & pharmaceutical bulletin 20050701
Short-term regulation of the alpha-ketoglutarate dehydrogenase complex by energy-linked and some other effectors. Biochemistry. Biokhimiia 20050701
Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels. Biochimica et biophysica acta 20050630
An NAD(+)-dependent glutamate dehydrogenase cloned from the ruminal ciliate protozoan, Entodinium caudatum. FEMS microbiology letters 20050615
Bioenergetics in glutaryl-coenzyme A dehydrogenase deficiency: a role for glutaryl-coenzyme A. The Journal of biological chemistry 20050610
Kinetic dissection of the catalytic mechanism of taurine:alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli. Biochemistry 20050607
Does dietary ornithine alpha-ketoglutarate supplementation protect the liver against ischemia-reperfusion injury? Clinical nutrition (Edinburgh, Scotland) 20050601
Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: implications for collagen cross-linking and treatment of fibrosis. Matrix biology : journal of the International Society for Matrix Biology 20050601
Selective inhibition of factor inhibiting hypoxia-inducible factor. Journal of the American Chemical Society 20050601
2-Oxoglutarate and the PII homologues NifI1 and NifI2 regulate nitrogenase activity in cell extracts of Methanococcus maripaludis. Molecular microbiology 20050601
Pretreatment of starved rats with ornithine alpha-ketoglutarate: effects on hepatic mRNA levels and plasma concentrations of three liver-secreted proteins. Nutrition (Burbank, Los Angeles County, Calif.) 20050601
Differential gene expression of collagen-binding small leucine-rich proteoglycans and lysyl hydroxylases, during mineralization by MC3T3-E1 cells cultured on titanium implant material. European journal of oral sciences 20050601
[Construction of recombinant Escherichia coli strains producing poly (4-hydroxybutyric acid) homopolyester from glucose]. Wei sheng wu xue bao = Acta microbiologica Sinica 20050601
Methylophilus quaylei sp. nov., a new aerobic obligately methylotrophic bacterium. Systematic and applied microbiology 20050601
Enhanced expression of a novel dioxygenase during the early developmental stage of tomato fruit. Journal of plant physiology 20050601
Robustness of downhill folding: guidelines for the analysis of equilibrium folding experiments on small proteins. Biochemistry 20050524
Dynamics of glutamate synthesis and excretion fluxes in batch and continuous cultures of temperature-triggered Corynebacterium glutamicum. Bioprocess and biosystems engineering 20050501
Hepatic mitochondrial glutathione: transport and role in disease and toxicity. Toxicology and applied pharmacology 20050501
Role of glutathione transport processes in kidney function. Toxicology and applied pharmacology 20050501
Hypoxia-inducible factor-1 drives the motility of the erythroid progenitor cell line, UT-7/Epo, via autocrine motility factor. Experimental hematology 20050501
Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Annals of neurology 20050501
A novel mutation in the lysyl hydroxylase 1 gene causes decreased lysyl hydroxylase activity in an Ehlers-Danlos VIA patient. The Journal of investigative dermatology 20050501
Pyruvate administered after severe hypoglycemia reduces neuronal death and cognitive impairment. Diabetes 20050501
Severe cognitive impairment correlates with higher cerebrospinal fluid levels of lactate and pyruvate in a canine model of senile dementia. Progress in neuro-psychopharmacology & biological psychiatry 20050501
Ascorbate depletion: a critical step in nickel carcinogenesis? Environmental health perspectives 20050501
Allosteric NADP-glutamate dehydrogenase from aspergilli: purification, characterization and implications for metabolic regulation at the carbon-nitrogen interface. Microbiology (Reading, England) 20050501
Differential expression of cardiac muscle mitochondrial matrix proteins in broilers from ascites-resistant and susceptible lines. Poultry science 20050501
Protective effect of alpha-keto-beta-methyl-n-valeric acid on BV-2 microglia under hypoxia or oxidative stress. Annals of the New York Academy of Sciences 20050501
Investigations into biochemical changes of genetic hypertensive rats using 1H nuclear magnetic resonance-based metabonomics. Hypertension research : official journal of the Japanese Society of Hypertension 20050501
[Proteomics analysis on stressed myocardium injury-related proteins]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20050501
Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria. Biochemical and biophysical research communications 20050429
Gene expression and characterization of two 2-oxoacid:ferredoxin oxidoreductases from Aeropyrum pernix K1. FEBS letters 20050425
Vmax regulation through domain and subunit changes. The active form of phosphoglycerate dehydrogenase. Biochemistry 20050419
D-3-Phosphoglycerate dehydrogenase from Mycobacterium tuberculosis is a link between the Escherichia coli and mammalian enzymes. The Journal of biological chemistry 20050415
The Skp1 prolyl hydroxylase from Dictyostelium is related to the hypoxia-inducible factor-alpha class of animal prolyl 4-hydroxylases. The Journal of biological chemistry 20050415
The unexpected structural role of glutamate synthase [4Fe-4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit. Archives of biochemistry and biophysics 20050415
Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20050415
Substrate specificity of the human renal sodium dicarboxylate cotransporter, hNaDC-3, under voltage-clamp conditions. American journal of physiology. Renal physiology 20050401
New functions for parts of the Krebs cycle in procyclic Trypanosoma brucei, a cycle not operating as a cycle. The Journal of biological chemistry 20050401
PII signal transduction proteins: sensors of alpha-ketoglutarate that regulate nitrogen metabolism. Current opinion in microbiology 20050401
Protective effect of Premna tomentosa extract (L. verbanacae) on acetaminophen-induced mitochondrial dysfunction in rats. Molecular and cellular biochemistry 20050401
Dynamics of intracellular metabolites of glycolysis and TCA cycle during cell-cycle-related oscillation in Saccharomyces cerevisiae. Biotechnology and bioengineering 20050330
Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity. The Journal of biological chemistry 20050325
The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL. Biochimica et biophysica acta 20050322
Steady-state and transient kinetic analyses of taurine/alpha-ketoglutarate dioxygenase: effects of oxygen concentration, alternative sulfonates, and active-site variants on the FeIV-oxo intermediate. Biochemistry 20050315
Isolation and characterization of enzymes involved in lysine catabolism from sorghum seeds. Journal of agricultural and food chemistry 20050309
Mutational analysis of the nucleotide-binding domain of the anti-activator NifL. Journal of molecular biology 20050304
Anaerobic and aerobic enzyme activities in human skeletal muscle from children and adults. Pediatric research 20050301
A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency. Human mutation 20050301
Glutathione depletion resulting in selective mitochondrial complex I inhibition in dopaminergic cells is via an NO-mediated pathway not involving peroxynitrite: implications for Parkinson's disease. Journal of neurochemistry 20050301
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets. Analytical chemistry 20050301
Unique mechanistic features of post-translational regulation of glutamine synthetase activity in Methanosarcina mazei strain Gö1 in response to nitrogen availability. Molecular microbiology 20050301
Dissimilation of cysteate via 3-sulfolactate sulfo-lyase and a sulfate exporter in Paracoccus pantotrophus NKNCYSA. Microbiology (Reading, England) 20050301
Comparative study of flux redistribution of metabolic pathway in glutamate production by two coryneform bacteria. Metabolic engineering 20050301
Mitochondrial aging and dysfunction in Alzheimer's disease. Progress in neuro-psychopharmacology & biological psychiatry 20050301
Chemopreventive effect of piperine on mitochondrial TCA cycle and phase-I and glutathione-metabolizing enzymes in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice. Molecular and cellular biochemistry 20050301
Teaching about citric acid cycle using plant mitochondrial preparations: Some assays for use in laboratory courses*. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 20050301
Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes. Molecules and cells 20050227
Succinate complex crystal structures of the alpha-ketoglutarate-dependent dioxygenase AtsK: steric aspects of enzyme self-hydroxylation. The Journal of biological chemistry 20050218
Regulation of nif expression in Methanococcus maripaludis: roles of the euryarchaeal repressor NrpR, 2-oxoglutarate, and two operators. The Journal of biological chemistry 20050218
Kinetic properties and metabolic contributions of yeast mitochondrial and cytosolic NADP+-specific isocitrate dehydrogenases. The Journal of biological chemistry 20050211
Aluminum triggers decreased aconitase activity via Fe-S cluster disruption and the overexpression of isocitrate dehydrogenase and isocitrate lyase: a metabolic network mediating cellular survival. The Journal of biological chemistry 20050204
Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause D-2-hydroxyglutaric aciduria. American journal of human genetics 20050201
Fatty acid synthesis and the oxidative pentose phosphate pathway in developing embryos of oilseed rape (Brassica napus L.). Journal of experimental botany 20050201
Nitrogen fixation: key genetic regulatory mechanisms. Biochemical Society transactions 20050201
Nitrogen assimilation and nitrogen control in cyanobacteria. Biochemical Society transactions 20050201
Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceraldehyde-3-phosphate dehydrogenase. Chemical research in toxicology 20050201
Inhibition by N'-nitrosonornicotine of the catalytic activity of glutamate dehydrogenase in alpha-ketoglutarate amination. Journal of enzyme inhibition and medicinal chemistry 20050201
Krebs cycle intermediates modulate thiobarbituric acid reactive species (TBARS) production in rat brain in vitro. Neurochemical research 20050201
Aerobic organic carbon mineralization by sulfate-reducing bacteria in the oxygen-saturated photic zone of a hypersaline microbial mat. Microbial ecology 20050201
Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability. Journal of molecular biology 20050121
Characterization of a second Arabidopsis thaliana prolyl 4-hydroxylase with distinct substrate specificity. The Journal of biological chemistry 20050114
Evaluation of brain mitochondrial glutamate and alpha-ketoglutarate transport under physiologic conditions. Journal of neuroscience research 20050101
4-Hydroxyphenylpyruvate dioxygenase. Archives of biochemistry and biophysics 20050101
Structure--function studies on the iron-sulfur flavoenzyme glutamate synthase: an unexpectedly complex self-regulated enzyme. Archives of biochemistry and biophysics 20050101
A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases. Analytical biochemistry 20050101
Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion. American journal of physiology. Endocrinology and metabolism 20050101
Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats. Biochemical pharmacology 20050101
BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death. Biochemical pharmacology 20050101
The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4. Nature biotechnology 20050101
The human malaria parasite Plasmodium falciparum possesses two distinct dihydrolipoamide dehydrogenases. Molecular microbiology 20050101
Overexpression of lysyl hydroxylase-2b leads to defective collagen fibrillogenesis and matrix mineralization. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050101
Bioinformatic mapping of AlkB homology domains in viruses. BMC genomics 20050101
Disruption of MRG19 results in altered nitrogen metabolic status and defective pseudohyphal development in Saccharomyces cerevisiae. Microbiology (Reading, England) 20050101
Structural basis for stereo-specific catalysis in NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans. The FEBS journal 20050101
Cyclic nucleotide binding proteins in the Arabidopsis thaliana and Oryza sativa genomes. BMC bioinformatics 20050101
Inhibition of the alpha-ketoglutarate dehydrogenase complex by the myeloperoxidase products, hypochlorous acid and mono-N-chloramine. Journal of neurochemistry 20050101
Hesperidin, a citrus bioflavonoid, decreases the oxidative stress produced by carbon tetrachloride in rat liver and kidney. BMC pharmacology 20050101
Reactive oxygen species production in the mitochondrial matrix: implications for the mechanism of mitochondrial mutation accumulation. Rejuvenation research 20050101
Supplementation of L-carnitine improves mitochondrial enzymes in heart and skeletal muscle of aged rats. Experimental aging research 20050101
Dual substrate recognition of aminotransferases. Chemical record (New York, N.Y.) 20050101
Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase. Proteome science 20050101
Role of mitochondrial dysfunction and oxidative stress in the pathogenesis of selective neuronal loss in Wernicke's encephalopathy. Molecular neurobiology 20050101
The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration. Molecular neurobiology 20050101
Mutation analysis of the PLOD1 gene: an efficient multistep approach to the molecular diagnosis of the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA). Molecular genetics and metabolism 20050101
Modeling Lactococcus lactis using a genome-scale flux model. BMC microbiology 20050101
Clonogenic growth of human breast cancer cells co-cultured in direct contact with serum-activated fibroblasts. Breast cancer research : BCR 20050101
Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene. Journal of biomedicine & biotechnology 20050101
Protective effect of bacoside A on cigarette smoking-induced brain mitochondrial dysfunction in rats. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20050101
Solution structure of the fifth and sixth transmembrane segments of the mitochondrial oxoglutarate carrier. Molecular membrane biology 20050101
Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources. Antioxidants & redox signaling 20050101
[Carbon metabolism of filamentous anoxygenic phototrophic bacteria of the family Oscillochloridaceae]. Mikrobiologiia 20050101
Sequence-based discovery of the human and rodent peroxisomal proteome. Applied bioinformatics 20050101
Ammonium assimilation in cyanobacteria. Photosynthesis research 20050101
Glutamate synthase: structural, mechanistic and regulatory properties, and role in the amino acid metabolism. Photosynthesis research 20050101
[Dynamics of the reversible transition of Vibrio cholerae into the uncultivable state in the presence of organic and inorganic microcosmic components]. Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20050101
Fumarase deficiency presenting with periventricular cysts. Journal of inherited metabolic disease 20050101
An Ehlers-Danlos syndrome type VIA patient with cystic malformations of the meninges. European journal of dermatology : EJD 20050101
Purification and kinetic studies of recombinant gibberellin dioxygenases. BMC plant biology 20050101
[The modification of nitric oxide production by exogenous substrates of Krebs cycle during acute hypoxia]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101
Natural history of S-adenosylmethionine-binding proteins. BMC structural biology 20050101
Characterization of the metabolic shift between oxidative and fermentative growth in Saccharomyces cerevisiae by comparative 13C flux analysis. Microbial cell factories 20050101
Metabolic profiling of laser microdissected vascular bundles of Arabidopsis thaliana. Plant methods 20050101
Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis. Critical care (London, England) 20050101
Role of cultivation media in the development of yeast strains for large scale industrial use. Microbial cell factories 20050101
Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers. BMC biochemistry 20050101
Assessing the precision of high-throughput computational and laboratory approaches for the genome-wide identification of protein subcellular localization in bacteria. BMC genomics 20050101
Substrate-induced conformational changes of the mitochondrial oxoglutarate carrier: a spectroscopic and molecular modelling study. Molecular membrane biology 20050101
Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies. BMC genomics 20050101
Kinetic characterization of human hydroxyacid-oxoacid transhydrogenase: relevance to D-2-hydroxyglutaric and gamma-hydroxybutyric acidurias. Journal of inherited metabolic disease 20050101
[Effect of intermittent hypoxic hypoxia on energy supply of rat skeletal muscle during adaptation to physical load]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20050101
L-Arabinose 1-dehydrogenase: a novel enzyme involving in bacterial L-arabinose metabolism. Nucleic acids symposium series (2004) 20050101
Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation. The Journal of biological chemistry 20041231
Complex formation and catalytic activation by the PII signaling protein of N-acetyl-L-glutamate kinase from Synechococcus elongatus strain PCC 7942. The Journal of biological chemistry 20041231
Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli. Journal of the American Chemical Society 20041229
Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah. The Journal of biological chemistry 20041217
Mitochondria/nuclear signaling of alternative oxidase gene expression occurs through distinct pathways involving organic acids and reactive oxygen species. Plant cell reports 20041201
Tricarboxylic acid cycle enzymes following thiamine deficiency. Neurochemistry international 20041201
Proteomic identification of collagens and related proteins in human fibroblasts. Amino acids 20041201
Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases. Biochemical Society transactions 20041201
Phenotypic and molecular characterization of Bruck syndrome (osteogenesis imperfecta with contractures of the large joints) caused by a recessive mutation in PLOD2. American journal of medical genetics. Part A 20041201
Heterogeneous basis of the type VIB form of Ehlers-Danlos syndrome (EDS VIB) that is unrelated to decreased collagen lysyl hydroxylation. American journal of medical genetics. Part A 20041201
Effects of ornithine on neutrophil (PMN) free amino acid and alpha-keto acid profiles and immune functions in vitro. Amino acids 20041201
Glutamate dehydrogenase of tobacco is mainly induced in the cytosol of phloem companion cells when ammonia is provided either externally or released during photorespiration. Plant physiology 20041201
Decreased expression of lysyl hydroxylase 2 (LH2) in skin fibroblasts from three Ehlers-Danlos patients does not result from mutations in either the coding or proximal promoter region of the LH2 gene. Molecular genetics and metabolism 20041201
Insertion of transposon Tn5tac1 in the Sinorhizobium meliloti malate dehydrogenase (mdh) gene results in conditional polar effects on downstream TCA cycle genes. Molecular plant-microbe interactions : MPMI 20041201
Effect of alpha-ketoglutarate against selenite cataract formation. Experimental eye research 20041201
Interaction of N-acetylglutamate kinase with a PII-like protein in rice. Plant & cell physiology 20041201
Isolation and characterization of cytosolic alanine aminotransferase isoforms from starved rat liver. Molecular and cellular biochemistry 20041201
Regulation by magnesium of potato tuber mitochondrial respiratory activities. Journal of bioenergetics and biomembranes 20041201
The fate of P2Y-related orphan receptors: GPR80/99 and GPR91 are receptors of dicarboxylic acids. Purinergic signalling 20041201
GPR80/99, proposed to be the P2Y(15) receptor activated by adenosine and AMP, is not a P2Y receptor. Purinergic signalling 20041201
Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation. Biochemistry 20041116
Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20041115
Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity. The Biochemical journal 20041101
Anaplerotic input is sufficient to induce time-dependent potentiation of insulin release in rat pancreatic islets. American journal of physiology. Endocrinology and metabolism 20041101
Molecular dynamics simulation of the interaction between the complex iron-sulfur flavoprotein glutamate synthase and its substrates. Protein science : a publication of the Protein Society 20041101
Copper(II) complexes with substituted thiosemicarbazones of alpha-ketoglutaric acid: synthesis, X-ray structures, DNA binding studies, and nuclease and biological activity. Inorganic chemistry 20041101
Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate. Journal of cardiovascular pharmacology 20041101
Gender-specific proteomic alterations in glycolytic and mitochondrial pathways in aging monkey hearts. Journal of molecular and cellular cardiology 20041101
Effect of low- and high-intensity pulsed ultrasound on collagen post-translational modifications in MC3T3-E1 osteoblasts. Calcified tissue international 20041101
Amino acid transamination in permeabilised cells of Lactobacillus helveticus, Lb. paracasei and Lb. danicus. The Journal of dairy research 20041101
H2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial depolarisation. Toxicology 20041015
A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenase. The Journal of biological chemistry 20041008
Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. The Journal of biological chemistry 20041008
Conformational flexibility of the C terminus with implications for substrate binding and catalysis revealed in a new crystal form of deacetoxycephalosporin C synthase. Journal of molecular biology 20041008
Comparison of ion-pair chromatography and capillary zone electrophoresis for the assay of organic acids as markers of abnormal metabolism. Journal of chromatography. A 20041008
Intermediates of Krebs cycle correct the depression of the whole body oxygen consumption and lethal cooling in barbiturate poisoning in rat. Toxicology 20041001
Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath). PLoS biology 20041001
Identification of distinct genes with restricted expression in the somitic mesoderm in Xenopus embryo. Gene expression patterns : GEP 20041001
Metabolic flux analysis for calcium dependent antibiotic (CDA) production in Streptomyces coelicolor. Metabolic engineering 20041001
Dose dependency of the effect of ornithine alpha-ketoglutarate on tissue glutamine concentrations and hypercatabolic response in endotoxaemic rats. The British journal of nutrition 20041001
Effect of ascorbate, nitrate and nitrite on the amount of flavour compounds produced from leucine by Staphylococcus xylosus and Staphylococcus carnosus. Meat science 20041001
Branched-chain amino acids and neurotransmitter metabolism: expression of cytosolic branched-chain aminotransferase (BCATc) in the cerebellum and hippocampus. The Journal of comparative neurology 20040927
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress. The Journal of biological chemistry 20040924
Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. Biochemistry 20040921
Distinct intracellular localization of Gpd1p and Gpd2p, the two yeast isoforms of NAD+-dependent glycerol-3-phosphate dehydrogenase, explains their different contributions to redox-driven glycerol production. The Journal of biological chemistry 20040917
Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908
Characterization of collagenous peptides bound to lysyl hydroxylase isoforms. The Journal of biological chemistry 20040903
Urease-glutamic dehydrogenase biosensor for screening heavy metals in water and soil samples. Analytical and bioanalytical chemistry 20040901
The oxo/peroxo debate: a nonheme iron perspective. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20040901
Glutamatergic neurotransmission and neuronal glucose oxidation are coupled during intense neuronal activation. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040901
PCR method based on the ogdH gene for the detection of Salmonella spp. from chicken meat samples. Journal of microbiology (Seoul, Korea) 20040901
Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria--case studies. Mitochondrion 20040901
Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity. The Journal of biological chemistry 20040806
Interaction of L-glutamate oxidase with triazine dyes: selection of ligands for affinity chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040805
Regulation of transcription and activity of Rhizobium etli glutaminase A. Biochimica et biophysica acta 20040804
Lysyl hydroxylase-2b directs collagen cross-linking pathways in MC3T3-E1 cells. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040801
Flux to acetate and lactate excretions in industrial fermentations: physiological and biochemical implications. Journal of industrial microbiology & biotechnology 20040801
Krebs cycle enzymes from livers of old mice are differentially regulated by caloric restriction. Experimental gerontology 20040801
Ornithine alpha-ketoglutarate supplementation influences motor activity in healthy rats. Clinical nutrition (Edinburgh, Scotland) 20040801
Cellular oxygen sensing need in CNS function: physiological and pathological implications. The Journal of experimental biology 20040801
Mitochondrial enzymes and endoplasmic reticulum calcium stores as targets of oxidative stress in neurodegenerative diseases. Journal of bioenergetics and biomembranes 20040801
Molecular biology of erythropoietin. Internal medicine (Tokyo, Japan) 20040801
Addition of α-ketoglutarate enhances formation of volatiles by Staphylococcus carnosus during sausage fermentation. Meat science 20040801
Identification of a dehydrogenase acting on D-2-hydroxyglutarate. The Biochemical journal 20040701
Molecular and biochemical characterization of D-phosphoglycerate dehydrogenase from Entamoeba histolytica. A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways. European journal of biochemistry 20040701
Alpha-ketoglutarate treatment early in postnatal life improves bone density in lambs at slaughter. Bone 20040701
Increased formation of pyridinoline cross-links due to higher telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon. Matrix biology : journal of the International Society for Matrix Biology 20040701
Glutamic acid removal and PHB storage in the activated sludge process under dynamic conditions. Biotechnology and bioengineering 20040630
Inhibitory effects of Cimicifuga heracleifolia extract on glutamate formation and glutamate dehydrogenase activity in cultured islets. Molecules and cells 20040630
Immunochemical identification of coenzyme Q0-dihydrolipoamide adducts in the E2 components of the alpha-ketoglutarate and pyruvate dehydrogenase complexes partially explains the cellular toxicity of coenzyme Q0. The Journal of biological chemistry 20040625
Inhibition of thiamin diphosphate dependent enzymes by 3-deazathiamin diphosphate. Organic & biomolecular chemistry 20040621
Limited transfer of cytosolic NADH into mitochondria at high cardiac workload. American journal of physiology. Heart and circulatory physiology 20040601
Endogenous 2-oxoacids differentially regulate expression of oxygen sensors. The Biochemical journal 20040601
Respective roles of the glutamine synthetase/glutamate synthase cycle and glutamate dehydrogenase in ammonium and amino acid metabolism during germination and post-germinative growth in the model legume Medicago truncatula. Planta 20040601
The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants. Neurochemistry international 20040601
A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependent changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity. The Analyst 20040601
The potential biological mechanisms of arsenic-induced diabetes mellitus. Toxicology and applied pharmacology 20040601
The Synechococcus elongatus P signal transduction protein controls arginine synthesis by complex formation with N-acetyl-L-glutamate kinase. Molecular microbiology 20040601
L-ornithine alpha-ketoglutarate in HIV infection: effects on muscle, gastrointestinal, and immune functions. Nutrition (Burbank, Los Angeles County, Calif.) 20040601
Role of the amino-terminal GAF domain of the NifA activator in controlling the response to the antiactivator protein NifL. Molecular microbiology 20040601
Absorption of alpha-ketoglutarate by the gastrointestinal tract of pigs. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040601
Upregulation of the mitochondrial phosphate carrier during freezing in the wood frog Rana sylvatica: potential roles of transporters in freeze tolerance. Journal of bioenergetics and biomembranes 20040601
Global carbon/nitrogen control by PII signal transduction in cyanobacteria: from signals to targets. FEMS microbiology reviews 20040601
A challenge for 21st century molecular biology and biochemistry: what are the causes of obligate autotrophy and methanotrophy? FEMS microbiology reviews 20040601
Regulation of cellular plasticity and resilience by mood stabilizers: the role of AMPA receptor trafficking. Dialogues in clinical neuroscience 20040601
[DOOR (deafness, onychodystrophy, osteodystrophy, mental retardation) syndrome]. Orvosi hetilap 20040530
Prolyl 3-hydroxylase 1, enzyme characterization and identification of a novel family of enzymes. The Journal of biological chemistry 20040528
3-Isopropylmalate is the major endogenous substrate of the Saccharomyces cerevisiae trans-aconitate methyltransferase. Biochemistry 20040525
A hybrid density functional study of O-O bond cleavage and phenyl ring hydroxylation for a biomimetic non-heme iron complex. Inorganic chemistry 20040517
Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase. The Journal of biological chemistry 20040514
Physiology: orphan detectors of metabolism. Nature 20040513
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. Nature 20040513
Conversion into GABA (gamma-aminobutyric acid) may reduce the capacity of L-glutamine as an insulin secretagogue. The Biochemical journal 20040501
Oxygen sensing by HIF hydroxylases. Nature reviews. Molecular cell biology 20040501
Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo. Annals of neurology 20040501
Aberrant activity of the DNA repair enzyme AlkB. Journal of inorganic biochemistry 20040501
Collagen prolyl 4-hydroxylase tetramers and dimers show identical decreases in Km values for peptide substrates with increasing chain length: mutation of one of the two catalytic sites in the tetramer inactivates the enzyme by more than half. The Journal of biological chemistry 20040430
The first biosynthetic studies of the azinomycins: acetate incorporation into azinomycin B. Chemical communications (Cambridge, England) 20040421
Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules. American journal of physiology. Renal physiology 20040401
Hyperinsulinism/hyperammonemia syndrome: insights into the regulatory role of glutamate dehydrogenase in ammonia metabolism. Molecular genetics and metabolism 20040401
Ammonia toxicity to the brain and creatine. Molecular genetics and metabolism 20040401
Inhibition of chlorophyll biosynthesis by mercury in excised etiolated maize leaf segments during greening: effect of 2-oxoglutarate. Indian journal of experimental biology 20040401
Flavonoid methylation: a novel 4'-O-methyltransferase from Catharanthus roseus, and evidence that partially methylated flavanones are substrates of four different flavonoid dioxygenases. Phytochemistry 20040401
[Effects of ovarian stimulation on serum concentrations of lipids and ketone bodies in patients undergoing IVF/ICSI treatment]. Zentralblatt fur Gynakologie 20040401
Crystal structure of the alkylsulfatase AtsK: insights into the catalytic mechanism of the Fe(II) alpha-ketoglutarate-dependent dioxygenase superfamily. Biochemistry 20040323
Mental retardation and hypotonia seen in the knock out mouse for Canavan disease is not due to succinate semialdehyde dehydrogenase deficiency. Neuroscience letters 20040318
Functional features and genomic organization of mouse NaCT, a sodium-coupled transporter for tricarboxylic acid cycle intermediates. The Biochemical journal 20040315
Influence of compartmental localization on the function of yeast NADP+-specific isocitrate dehydrogenases. Archives of biochemistry and biophysics 20040315
Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases. The Journal of biological chemistry 20040312
Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms. The Journal of biological chemistry 20040305
Expression, purification, crystallization, and preliminary X-ray analysis of the N-terminal domain of Escherichia coli adenylyl transferase. Protein expression and purification 20040301
Directed evolution relieves product inhibition and confers in vivo function to a rationally designed tyrosine aminotransferase. Protein science : a publication of the Protein Society 20040301
Urinary alpha-ketoglutarate is elevated in patients with hyperinsulinism-hyperammonemia syndrome. Clinica chimica acta; international journal of clinical chemistry 20040301
Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity. Journal of neurochemistry 20040301
Regulation and differential expression of gdhA encoding NADP-specific glutamate dehydrogenase in Neisseria meningitidis clinical isolates. Molecular microbiology 20040301
Production and export of metabolites from liver and heart mitochondria and anaplerosis. Molecular and cellular biochemistry 20040301
Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease. Neurochemical research 20040301
Substantial linkage disequilibrium across the dihydrolipoyl succinyltransferase gene region without Alzheimer's disease association. Neurochemical research 20040301
Glutamate synthase: a fascinating pathway from L-glutamine to L-glutamate. Cellular and molecular life sciences : CMLS 20040301
Mechanism of dioxygen activation in 2-oxoglutarate-dependent enzymes: a hybrid DFT study. Chemistry (Weinheim an der Bergstrasse, Germany) 20040220
The SLC22 drug transporter family. Pflugers Archiv : European journal of physiology 20040201
Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation. American journal of physiology. Endocrinology and metabolism 20040201
Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice. Journal of neurochemistry 20040201
A novel biotin protein required for reductive carboxylation of 2-oxoglutarate by isocitrate dehydrogenase in Hydrogenobacter thermophilus TK-6. Molecular microbiology 20040201
Retinal function loss after monocarboxylate transport inhibition. Investigative ophthalmology & visual science 20040201
Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis. Plant physiology 20040201
A role for the 2-oxoglutarate carrier in glutathione transport into hepatocyte mitochondria? Hepatology (Baltimore, Md.) 20040201
Differentiation of dicarboxylate transporters in mesophyll and bundle sheath chloroplasts of maize. Plant & cell physiology 20040201
Purification and properties of cytosolic alanine aminotransferase from the liver of two freshwater fish, Clarias batrachus and Labeo rohita. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040201
Metal-induced stabilization of trypsin modified with alpha-oxoglutaric acid. Biotechnology letters 20040201
Mechanistic studies on three 2-oxoglutarate-dependent oxygenases of flavonoid biosynthesis: anthocyanidin synthase, flavonol synthase, and flavanone 3beta-hydroxylase. The Journal of biological chemistry 20040109
Regulation of sodium-dicarboxylate cotransporter-3 from winter flounder kidney by protein kinase C. American journal of physiology. Renal physiology 20040101
In situ evidence of an alternative oxidase and an uncoupling protein in the respiratory chain of Aspergillus fumigatus. The international journal of biochemistry & cell biology 20040101
Brittle cornea syndrome and its delineation from the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VI): report on 23 patients and review of the literature. American journal of medical genetics. Part A 20040101
In vitro uridylylation of the Azospirillum brasilense N-signal transducing GlnZ protein. Protein expression and purification 20040101
The structural basis of cephalosporin formation in a mononuclear ferrous enzyme. Nature structural & molecular biology 20040101
Value of energy substrates in HTK and UW to protect human liver endothelial cells against ischemia and reperfusion injury. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20040101
A critical perspective of the use of (13)C-isotopomer analysis by GCMS and NMR as applied to cardiac metabolism. Metabolic engineering 20040101
Purification and characterization of a branched-chain amino acid aminotransferase from Lactobacillus paracasei subsp. paracasei CHCC 2115. Journal of applied microbiology 20040101
Factorial analysis of tricarboxylic acid cycle intermediates for optimization of zeaxanthin production from Flavobacterium multivorum. Journal of applied microbiology 20040101
Creatine transporters: a reappraisal. Molecular and cellular biochemistry 20040101
Inhibition of Krebs cycle and activation of glyoxylate cycle in the course of chronological aging of Saccharomyces cerevisiae. Compensatory role of succinate oxidation. Biochimie 20040101
Amino-acid-dependent, differential effects of ethanol on glucose production in rabbit kidney-cortex tubules. Alcohol and alcoholism (Oxford, Oxfordshire) 20040101
Entamoeba histolytica: kinetic and molecular evidence of a previously unidentified pyruvate kinase. Experimental parasitology 20040101
Hypoxia and hypoxia inducible factors (HIF) as important regulators of tumor physiology. Cancer treatment and research 20040101
NADP-glutamate dehydrogenase activity is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii. Current microbiology 20040101
Modulating the hypoxia-inducible factor signaling pathway: applications from cardiovascular disease to cancer. Current pharmaceutical design 20040101
Catabolism of leucine to branched-chain fatty acids in Staphylococcus xylosus. Journal of applied microbiology 20040101
The possibility of involvement of the pools of alpha-ketoglutaric acid in the biosynthesis of carotenoids in chloroplasts. Doklady. Biochemistry and biophysics 20040101
FeII/alpha-ketoglutarate-dependent hydroxylases and related enzymes. Critical reviews in biochemistry and molecular biology 20040101
Transcriptional regulation of protein complexes in yeast. Genome biology 20040101
Intracellular metabolic compartmentation assessed by 13C magnetic resonance spectroscopy. Neurochemistry international 20040101
Serial 13C-based flux analysis of an L-phenylalanine-producing E. coli strain using the sensor reactor. Biotechnology progress 20040101
[Levels of unified metabolites and thyroid hormones in blood and oral fluid of children with minimal brain dysfunction]. Biomeditsinskaia khimiia 20040101
The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity. BMC cell biology 20040101
Alpha-Ketoglutarate dehydrogenase and lipoic acid synthase are important for the functioning of peroxisomes of Saccharomyces cerevisiae. Cellular & molecular biology letters 20040101
The effect of alpha-ketoglutaric acid on amino acid utilization by nonstarter Lactobacillus spp. isolated from Cheddar cheese. Letters in applied microbiology 20040101
[Etiology and pathogenesis of Parkinson's disease: from mitochondrial dysfunctions to familial Parkinson's disease]. Rinsho shinkeigaku = Clinical neurology 20040101
The pattern and kinetics of substrate metabolism of Campylobacter jejuni and Campylobacter coli. Letters in applied microbiology 20040101
Interactions of benzylpenicillin and non-steroidal anti-inflammatory drugs with the sodium-dependent dicarboxylate transporter NaDC-3. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101
RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells. Molecular cancer 20040101
Mitochondrial enzymes in schizophrenia. Journal of molecular neuroscience : MN 20040101
Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis. BMC microbiology 20040101
Solution structure of the first and second transmembrane segments of the mitochondrial oxoglutarate carrier. Molecular membrane biology 20040101
[New thermophilic methanotrophs of the genus Methylocaldum]. Mikrobiologiia 20040101
Age-dependent alterations in mitochondrial enzymes in cortex, striatum and hippocampus of rat brain -- potential role of L-Carnitine. Biogerontology 20040101
Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts. Respiratory research 20040101
Molecular characterization and functional expression of flavonol 6-hydroxylase. BMC plant biology 20040101
Hierarchical structure and modules in the Escherichia coli transcriptional regulatory network revealed by a new top-down approach. BMC bioinformatics 20040101
[Effect of K-ATP channel opener-pinacidil on the liver mitochondria function in rats with different resistance to hypoxia during stress]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101
[Myocardium mitochondria functional state during adaptation to intermittent hypoxia and treatment with L-arginine]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101
Use of Lactococcus lactis subsp. cremoris NCDO 763 and α-ketoglutarate to improve the sensory quality of dry fermented sausages. Meat science 20040101
Exploring the overproduction of amino acids using the bilevel optimization framework OptKnock. Biotechnology and bioengineering 20031230
The molecular and cellular physiology of basolateral organic anion transport in mammalian renal tubules. Biochimica et biophysica acta 20031230
L-carnitine ameliorates abnormal vulnerability of steatotic rat livers to cold ischemic preservation. Transplantation 20031227
Synthesis of (3S,5R)-carbapenam-3-carboxylic acid and its role in carbapenem biosynthesis and the stereoinversion problem. Journal of the American Chemical Society 20031224
Impaired oxidative phosphorylation in hepatic mitochondria in growth-retarded rats. American journal of physiology. Endocrinology and metabolism 20031201
Phylogeny of the bacterial superfamily of Crp-Fnr transcription regulators: exploiting the metabolic spectrum by controlling alternative gene programs. FEMS microbiology reviews 20031201
Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel. Molecular pharmacology 20031201
Heterocyst development in Anabaena. Current opinion in microbiology 20031201
Substrate specificity of glutaminyl cyclases from plants and animals. Biological chemistry 20031201
Babesia gibsoni-specific isoenzymes related to energy metabolism of the parasite in infected erythrocytes. The Journal of parasitology 20031201
Thiamin deficiency and brain disorders. Nutrition research reviews 20031201
Collection and characterisation of bacterial membrane proteins. FEBS letters 20031127
Steady-state kinetics and molecular evolution of Escherichia coli MenD [(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase], an anomalous thiamin diphosphate-dependent decarboxylase-carboligase. Biochemistry 20031125
Oxidative alpha-ketoglutarate dehydrogenase inhibition via subtle elevations in monoamine oxidase B levels results in loss of spare respiratory capacity: implications for Parkinson's disease. The Journal of biological chemistry 20031121
Role of the glutamate dehydrogenase reaction in furnishing aspartate nitrogen for urea synthesis: studies in perfused rat liver with 15N. The Biochemical journal 20031115
Minimal methylated substrate and extended substrate range of Escherichia coli AlkB protein, a 1-methyladenine-DNA dioxygenase. The Journal of biological chemistry 20031107
The C-4 stereochemistry of leucocyanidin substrates for anthocyanidin synthase affects product selectivity. Bioorganic & medicinal chemistry letters 20031103
An increase in the level of 2-oxoglutarate promotes heterocyst development in the cyanobacterium Anabaena sp. strain PCC 7120. Microbiology (Reading, England) 20031101
Effects of hypoxia and intracellular iron chelation on hypoxia-inducible factor-1alpha and -1beta in the rat carotid body and glomus cells. Histochemistry and cell biology 20031101
Oxygen tension regulates the expression of a group of procollagen hydroxylases. European journal of biochemistry 20031101
[Regulation of carbon source partitioning in plants: all about regulation in response to internal ratio of C and N]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20031101
The significance of organic carbon compounds for in situ metabolism and chemotaxis of phototrophic consortia. Environmental microbiology 20031101
[CaCO3 stimulates alpha-ketoglutarate accumulation during pyruvate fermentation by Torulopsis glabrata]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20031101
The influence of alpha-ketoglutarate (AKG) on mineralisation, mechanical and structural properties of ulna in turkey under conditions of osteotomy and denervation. Ortopedia, traumatologia, rehabilitacja 20031030
Identification of PLOD2 as telopeptide lysyl hydroxylase, an important enzyme in fibrosis. The Journal of biological chemistry 20031017
Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death. Journal of neuroscience research 20031015
Biochemical and spectroscopic studies on (S)-2-hydroxypropylphosphonic acid epoxidase: a novel mononuclear non-heme iron enzyme. Biochemistry 20031014
Oxygen and iron regulation of iron regulatory protein 2. The Journal of biological chemistry 20031010
Quantification of central metabolic fluxes in the facultative methylotroph methylobacterium extorquens AM1 using 13C-label tracing and mass spectrometry. Biotechnology and bioengineering 20031005
Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation. The Journal of biological chemistry 20031003
Formation of novel flavonoids in apple (Malusxdomestica) treated with the 2-oxoglutarate-dependent dioxygenase inhibitor prohexadione-Ca. Phytochemistry 20031001
Ammonia assimilation by Saccharomyces cerevisiae. Eukaryotic cell 20031001
1H NMR pattern recognition and 31P NMR studies with d-Serine in rat urine and kidney, time- and dose-related metabolic effects. Chemical research in toxicology 20031001
Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity. Antioxidants & redox signaling 20031001
Regulation of NAD- and NADP-dependent isocitrate dehydrogenases by reduction levels of pyridine nucleotides in mitochondria and cytosol of pea leaves. Biochimica et biophysica acta 20030930
Tor1/2 regulation of retrograde gene expression in Saccharomyces cerevisiae derives indirectly as a consequence of alterations in ammonia metabolism. The Journal of biological chemistry 20030919
Determination of tricarboxylic acid cycle acids and other related substances in cultured mammalian cells by gradient ion-exchange chromatography with suppressed conductivity detection. Journal of chromatography. A 20030919
The potential of dairy lactic acid bacteria to metabolise amino acids via non-transaminating reactions and endogenous transamination. International journal of food microbiology 20030915
Occurrence of two different glutamate dehydrogenase activities in the halophilic bacterium Salinibacter ruber. FEMS microbiology letters 20030912
Instability of glutamate production by Corynebacterium glutamicum 2262 in continuous culture using the temperature-triggered process. Journal of biotechnology 20030904
Short-term training attenuates muscle TCA cycle expansion during exercise in women. Journal of applied physiology (Bethesda, Md. : 1985) 20030901
Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes. Diabetologia 20030901
Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion. Hepatology (Baltimore, Md.) 20030901
Investigation by 13C-NMR and tricarboxylic acid (TCA) deletion mutant analysis of pathways for succinate formation in Saccharomyces cerevisiae during anaerobic fermentation. Microbiology (Reading, England) 20030901
Regulation of root ion transporters by photosynthesis: functional importance and relation with hexokinase. The Plant cell 20030901
Effect of hyper- and microgravity on collagen post-translational controls of MC3T3-E1 osteoblasts. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030901
Alteration of citrate metabolism in cluster roots of white lupin. Plant & cell physiology 20030901
Therapeutic effect of Semecarpus anacardium Linn. nut milk extract on carbohydrate metabolizing and mitochondrial TCA cycle and respiratory chain enzymes in mammary carcinoma rats. The Journal of pharmacy and pharmacology 20030901
2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase. Bioorganic & medicinal chemistry letters 20030818
Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor. The Journal of biological chemistry 20030815
Identification, expression, and tissue distribution of the three rat lysyl hydroxylase isoforms. Biochemical and biophysical research communications 20030808
Cloning of a novel prolyl 4-hydroxylase subunit expressed in the fibrous cap of human atherosclerotic plaque. Circulation 20030805
The amino-terminal GAF domain of Azotobacter vinelandii NifA binds 2-oxoglutarate to resist inhibition by NifL under nitrogen-limiting conditions. The Journal of biological chemistry 20030801
Basolateral localization of flounder Na+-dicarboxylate cotransporter (fNaDC-3) in the kidney of Pleuronectes americanus. Pflugers Archiv : European journal of physiology 20030801
Thiamine deficiency results in downregulation of the GLAST glutamate transporter in cultured astrocytes. Glia 20030801
A continuous coupled enzyme assay for bacterial malonyl-CoA:acyl carrier protein transacylase (FabD). Analytical biochemistry 20030801
Novel proline hydroxylase activities in the pneumocandin-producing fungus Glarea lozoyensis responsible for the formation of trans 3- and trans 4-hydroxyproline. Applied microbiology and biotechnology 20030801
The Arabidopsis mutant dct is deficient in the plastidic glutamate/malate translocator DiT2. The Plant journal : for cell and molecular biology 20030801
Export of metabolites from pancreatic islet mitochondria as a means to study anaplerosis in insulin secretion. Metabolism: clinical and experimental 20030801
Carbon-source-dependent nitrogen regulation in Escherichia coli is mediated through glutamine-dependent GlnB signalling. Microbiology (Reading, England) 20030801
Anaplerotic reactions in tumour proliferation and apoptosis. Biochemical pharmacology 20030801
Summary of the Standards, Options and Recommendations for nutritional support in patients undergoing bone marrow transplantation (2002). British journal of cancer 20030801
Association analysis of bone mineral density and single nucleotide polymorphisms in two candidate genes on chromosome 1p36. Calcified tissue international 20030801
Kinetic studies on the inhibition of GABA-T by gamma-vinyl GABA and taurine. Journal of enzyme inhibition and medicinal chemistry 20030801
Effect of alpha-ketoglutarate and oxaloacetate on brain mitochondrial DNA damage and seizures induced by kainic acid in mice. Toxicology letters 20030720
Allosteric interactions and bifunctionality make the response of glutamine synthetase cascade system of Escherichia coli robust and ultrasensitive. The Journal of biological chemistry 20030718
Identification and cloning of genes encoding viomycin biosynthesis from Streptomyces vinaceus and evidence for involvement of a rare oxygenase. Gene 20030717
Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline. Journal of the American Chemical Society 20030716
NMR-based metabonomic studies on the biochemical effects of epicatechin in the rat. Journal of agricultural and food chemistry 20030702
Deficits in a tricarboxylic acid cycle enzyme in brains from patients with Parkinson's disease. Neurochemistry international 20030701
Impaired oxidative phosphorylation in skeletal muscle of intrauterine growth-retarded rats. American journal of physiology. Endocrinology and metabolism 20030701
Mitochondrial complex I, aconitase, and succinate dehydrogenase during hypoxia-reoxygenation: modulation of enzyme activities by MnSOD. American journal of physiology. Lung cellular and molecular physiology 20030701
Disease-related metabolites in culture medium of fibroblasts from patients with D-2-hydroxyglutaric aciduria, L-2-hydroxyglutaric aciduria, and combined D/L-2-hydroxyglutaric aciduria. Clinical chemistry 20030701
Ascorbic acid and alpha-tocopherol as potent modulators on arsenic induced toxicity in mitochondria. The Journal of nutritional biochemistry 20030701
A comparison between NMR and GCMS 13C-isotopomer analysis in cardiac metabolism. Molecular and cellular biochemistry 20030701
Characterization and regulation of NADP+-isocitrate dehydrogenase from Saccharopolyspora erythraea. Biotechnology letters 20030701
Functional properties and cellular distribution of the system A glutamine transporter SNAT1 support specialized roles in central neurons. The Journal of biological chemistry 20030627
The active conformation of glutamate synthase and its binding to ferredoxin. Journal of molecular biology 20030627
The first direct characterization of a high-valent iron intermediate in the reaction of an alpha-ketoglutarate-dependent dioxygenase: a high-spin FeIV complex in taurine/alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli. Biochemistry 20030624
Truncated product of the bifunctional DLST gene involved in biogenesis of the respiratory chain. The EMBO journal 20030616
Toxic effects of copper-based antineoplastic drugs (Casiopeinas) on mitochondrial functions. Biochemical pharmacology 20030615
Construction and expression of a humanized M2 autoantigen trimer and its application in the diagnosis of primary biliary cirrhosis. World journal of gastroenterology 20030615
Crystal structure of carbapenem synthase (CarC). The Journal of biological chemistry 20030606
Chronic hypoxia in development selectively alters the activities of key enzymes of glucose oxidative metabolism in brain regions. Neurochemical research 20030601
Purification and folding of recombinant bovine oxoglutarate/malate carrier by immobilized metal-ion affinity chromatography. Protein expression and purification 20030601
Regulation of amino acid uptake by carbon and nitrogen in Pinus sylvestris. Planta 20030601
Phosphate binder usage in kidney failure patients. Expert opinion on pharmacotherapy 20030601
Proteomic studies of diauxic lag in the differentiating prokaryote Streptomyces coelicolor reveal a regulatory network of stress-induced proteins and central metabolic enzymes. Molecular microbiology 20030601
Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis. Gastroenterology 20030601
Regulatory effects of 5'-deoxypyridoxal on glutamate dehydrogenase activity and insulin secretion in pancreatic islets. Biochimie 20030601
Aerobic growth deficient Haemophilus influenzae mutants are non-virulent: implications on metabolism. International journal of medical microbiology : IJMM 20030601
Toxicovigilance: new biochemical tool used in sulfonylurea herbicides toxicology studies. Acta pharmaceutica (Zagreb, Croatia) 20030601
Nutrition in the critically ill patient: part II. Parenteral nutrition. Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20030601
Tyrosinase protects human melanocytes from ROS-generating compounds. Biochemical and biophysical research communications 20030530
Substrate-induced conformational changes in Escherichia coli taurine/alpha-ketoglutarate dioxygenase and insight into the oligomeric structure. Biochemistry 20030520
Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. Journal of immunology (Baltimore, Md. : 1950) 20030515
The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a unique coenzyme B6-dependent enzyme. Journal of the American Chemical Society 20030514
The mitochondrial oxoglutarate carrier: structural and dynamic properties of transmembrane segment IV studied by site-directed spin labeling. Biochemistry 20030513
Na+-K+-ATPase alpha 2-gene and skeletal muscle characteristics in response to long-term overfeeding. Journal of applied physiology (Bethesda, Md. : 1985) 20030501
Evaluation of newly developed ELISA using 'MESACUP-2 test mitochondrial M2' kit for the diagnosis of primary biliary cirrhosis. Clinical biochemistry 20030501
Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacity. Pflugers Archiv : European journal of physiology 20030501
Crystallization of the proline-rich-peptide binding domain of human type I collagen prolyl 4-hydroxylase. Acta crystallographica. Section D, Biological crystallography 20030501
Crystallization and preliminary X-ray crystallographic analysis of d-phenylglycine aminotransferase from Pseudomonas stutzeri ST201. Acta crystallographica. Section D, Biological crystallography 20030501
Carbon supply and 2-oxoglutarate effects on expression of nitrate reductase and nitrogen-regulated genes in Synechococcus sp. strain PCC 7942. FEMS microbiology letters 20030425
Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status. Biochemistry 20030415
Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells. Cancer research 20030415
Procyclic Trypanosoma brucei do not use Krebs cycle activity for energy generation. The Journal of biological chemistry 20030411
Histidine 454 plays an important role in polymerization of human glutamate dehydrogenase. FEBS letters 20030410
Crystal structures of branched-chain amino acid aminotransferase complexed with glutamate and glutarate: true reaction intermediate and double substrate recognition of the enzyme. Biochemistry 20030408
Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation. Biochemistry 20030401
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophysical journal 20030401
Effect of DHLA on response of isolated rat urinary bladder to repetitive field stimulation. Molecular and cellular biochemistry 20030401
Comparative analysis of the Bradyrhizobium japonicum sucA region. Canadian journal of microbiology 20030401
The selectivity and inhibition of AlkB. The Journal of biological chemistry 20030321
Inhibition study of rhodanese by means of electrophoretically mediated microanalysis. Journal of chromatography. A 20030321
Retrieval-independent localization of lysyl hydroxylase in the endoplasmic reticulum via a peptide fold in its iron-binding domain. The Biochemical journal 20030315
Heat effect on the structure and activity of the recombinant glutamate dehydrogenase from a hyperthermophilic archaeon Pyrococcus horikoshii. Archives of biochemistry and biophysics 20030301
Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells. Molecular pharmacology 20030301
2-Oxo acid dehydrogenase complexes in redox regulation. European journal of biochemistry 20030301
The kinetic properties of various R258 mutants of deacetoxycephalosporin C synthase. European journal of biochemistry 20030301
Identification of photorespiratory glutamate:glyoxylate aminotransferase (GGAT) gene in Arabidopsis. The Plant journal : for cell and molecular biology 20030301
Reconstruction of C(3) and C(4) metabolism in Methylobacterium extorquens AM1 using transposon mutagenesis. Microbiology (Reading, England) 20030301
In vivo induction of insulin secretion by ornithine alpha-ketoglutarate: involvement of nitric oxide and glutamine. Metabolism: clinical and experimental 20030301
Performance of a recombinant strain of Streptomyces lividans for bioconversion of penicillin G to deacetoxycephalosporin G. Journal of industrial microbiology & biotechnology 20030301
Characterization of aspartate aminotransferase from the cyanobacterium Phormidium lapideum. Bioscience, biotechnology, and biochemistry 20030301
Effects of the changes in enzyme activities on metabolic flux redistribution around the 2-oxoglutarate branch in glutamate production by Corynebacterium glutamicum. Bioprocess and biosystems engineering 20030301
Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau. The Journal of biological chemistry 20030227
O2- and alpha-ketoglutarate-dependent tyrosyl radical formation in TauD, an alpha-keto acid-dependent non-heme iron dioxygenase. Biochemistry 20030225
(4-Hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis: the basis for ordered substrate addition. Biochemistry 20030225
Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level. Biochemistry 20030225
Analysis of low-molecular-mass organic acids using capillary zone electrophoresis-electrospray ionization mass spectrometry. Journal of chromatography. A 20030221
Changes in the ornithine cycle following ionising radiation cause a cytotoxic conditioning of the culture medium of H35 hepatoma cells. British journal of cancer 20030210
Alterations in mitochondrial function in a mouse model of hypertrophic cardiomyopathy. American journal of physiology. Heart and circulatory physiology 20030201
The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis. Seminars in cancer biology 20030201
The snakehead Channa asiatica accumulates alanine during aerial exposure, but is incapable of sustaining locomotory activities on land through partial amino acid catabolism. The Journal of experimental biology 20030201
Glutamine deprivation facilitates tumour necrosis factor induced bacterial translocation in Caco-2 cells by depletion of enterocyte fuel substrate. Gut 20030201
Enzymatic assay for determination of bicarbonate ion in plasma using urea amidolyase. Clinica chimica acta; international journal of clinical chemistry 20030201
Glutamate synthesis in barley roots: the role of the plastidic glucose-6-phosphate dehydrogenase. Planta 20030201
Effects of ornithine alpha-ketoglutarate on insulin secretion in rat pancreatic islets: implication of nitric oxide synthase and glutamine synthetase pathways. The British journal of nutrition 20030201
Multimethod characterization of the interaction of aluminum ion with alpha-ketoglutaric acid in acidic aqueous solutions. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030201
A 2-oxoglutarate-dependent dioxygenase is integrated in DIMBOA-biosynthesis. Phytochemistry 20030201
Skeletal muscle metabolism in Duchenne muscular dystrophy (DMD): an in-vitro proton NMR spectroscopy study. Magnetic resonance imaging 20030201
Inhibition of the alpha-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation. Biochimica et biophysica acta 20030120
A thermally sensitive loop in clostridial glutamate dehydrogenase detected by limited proteolysis. The Journal of biological chemistry 20030110
Aluminum detoxification in Pseudomonas fluorescens is mediated by oxalate and phosphatidylethanolamine. Biochimica et biophysica acta 20030102
The export of metabolites from mitochondria and anaplerosis in insulin secretion. Biochimica et biophysica acta 20030102
Urate transport via human PAH transporter hOAT1 and its gene structure. Kidney international 20030101
Reactive oxygen species are involved in the stimulation of the mitochondrial permeability transition by dihydrolipoate. Biochemical pharmacology 20030101
Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients. Nutrition (Burbank, Los Angeles County, Calif.) 20030101
Induction of glutamate dehydrogenase in the ovine fetal liver by dexamethasone infusion during late gestation. Experimental biology and medicine (Maywood, N.J.) 20030101
Metabolic flux redistribution in Corynebacterium glutamicum in response to osmotic stress. Applied microbiology and biotechnology 20030101
Intrinsic tryptophan fluorescence as a probe of metal and alpha-ketoglutarate binding to TfdA, a mononuclear non-heme iron dioxygenase. Journal of inorganic biochemistry 20030101
Transport of organic anions across the basolateral membrane of proximal tubule cells. Reviews of physiology, biochemistry and pharmacology 20030101
Purification and characterization of NADP-linked isocitrate dehydrogenase from the copper-tolerant wood-rotting basidiomycete Fomitopsis palustris. Bioscience, biotechnology, and biochemistry 20030101
Involvement of oxygen free radicals in the respiratory uncoupling induced by free calcium and ADP-magnesium in isolated cardiac mitochondria: comparing reoxygenation in cultured cardiomyocytes. Molecular and cellular biochemistry 20030101
Isolation of the bifunctional enzyme lysine 2-oxoglutarate reductase-saccharopine dehydrogenase from Phaseolus vulgaris. Amino acids 20030101
Redox regulation of homocysteine-dependent glutathione synthesis. Redox report : communications in free radical research 20030101
New enzymatic assay for serum urea nitrogen using urea amidolyase. Journal of clinical laboratory analysis 20030101
Alicycliphilus denitrificans gen. nov., sp. nov., a cyclohexanol-degrading, nitrate-reducing beta-proteobacterium. International journal of systematic and evolutionary microbiology 20030101
Molecular responses to hypoxia in tumor cells. Molecular cancer 20030101
Cataplerotic TCA cycle flux determined as glutamate-sustained oxygen consumption in primary cultures of astrocytes. Neurochemistry international 20030101
Enhancement of circulatory antioxidants by alpha-ketoglutarate during sodium valproate treatment in Wistar rats. Polish journal of pharmacology 20030101
[Arsenite-induced lipid peroxidation in Saccharomyces cerevisiae]. Mikrobiologiia 20030101
[Tricarboxylic acid cycle in energy metabolism and antioxidant cell defense in acute hypoxia]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101
An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). Genome biology 20030101
Altered expression of connective tissue genes in postnatal chondroinduced human dermal fibroblasts. Connective tissue research 20030101
[Carbohydrate metabolism of Bothriocephalus scorpii (Cestoda: Bothriocephalidae)]. Parazitologiia 20030101
A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1alpha (HIF-1alpha) does not impair Pro-564 hydroxylation. Molecular cancer 20030101
[Central metabolism in Acinetobacter sp. grown on ethanol]. Mikrobiologiia 20030101
[Biochemical characterization of the yeast Yarrowia lipolytica overproducing carboxylic acids from ethanol. Nitrogen metabolism enzymes]. Mikrobiologiia 20030101
Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101
Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB. BMC genomics 20030101
[Activity of the enzymes of carbon metabolism in Sulfobacillus sibiricus under various conditions of cultivation]. Mikrobiologiia 20030101
[Role of ATP-sensitive potassium channel activators in liver mitochondrial function in rats with different resistance to hypoxia]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101
Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease. Neurotoxicity research 20030101
[Effect of ATP-sensitive potassium channel modulators and intermittent hypoxia on mitochondrial respiration during stress]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101
Tryptophan metabolism via transamination. In vitro aminotransferase assay using dinitrophenylhydrazine method. Advances in experimental medicine and biology 20030101
Effect of ketoacids on H(2)O(2) induced cataract. Indian journal of clinical biochemistry : IJCB 20030101
DOOR syndrome: deficiency of E1 component of the 2-oxoglutarate dehydrogenase complex. American journal of medical genetics 20021215
The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration. The Journal of physiology 20021215
Experimental identification of downhill protein folding. Science (New York, N.Y.) 20021213
The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis. Biochemistry 20021210
Differential display of mRNAs associated with blood feeding in the midgut of the bloodsucking bug, Triatoma infestans. Parasitology research 20021201
Crystallization and preliminary X-ray structure analysis of isocitrate dehydrogenase from two hyperthermophiles, Aeropyrum pernix and Thermotoga maritima. Acta crystallographica. Section D, Biological crystallography 20021201
Structure of the monomeric isocitrate dehydrogenase: evidence of a protein monomerization by a domain duplication. Structure (London, England : 1993) 20021201
Tobacco plants were transformed by Agrobacterium rhizogenes infection during their evolution. The Plant journal : for cell and molecular biology 20021201
Glutaminolysis and insulin secretion: from bedside to bench and back. Diabetes 20021201
The impact of oxidative stress on Arabidopsis mitochondria. The Plant journal : for cell and molecular biology 20021201
Mercury toxicity and antioxidants: Part 1: role of glutathione and alpha-lipoic acid in the treatment of mercury toxicity. Alternative medicine review : a journal of clinical therapeutic 20021201
Isolation and sequence analysis of the rat dihydrolipoamide succinyltransferase gene. DNA sequence : the journal of DNA sequencing and mapping 20021201
Neonatal liver disease associated with placental transfer of anti-mitochondrial antibodies. Autoimmunity 20021201
Ornithine alpha-ketoglutarate modulates the levels of antioxidants and lipid peroxidation products in ammonium acetate treated rats. Indian journal of biochemistry & biophysics 20021201
A metabolic role of the glyoxylate and tricarboxylic acid cycles for development of the copper-tolerant brown-rot fungus Fomitopsis palustris. FEMS microbiology letters 20021119
Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions. The Biochemical journal 20021115
Cytotoxicity of dopamine-derived tetrahydroisoquinolines on melanoma cells. Biochemical pharmacology 20021115
Renal organic anion transport: a comparative and cellular perspective. Biochimica et biophysica acta 20021113
Amish lethal microcephaly: a new metabolic disorder with severe congenital microcephaly and 2-ketoglutaric aciduria. American journal of medical genetics 20021101
Renal disposition of a furan dicarboxylic acid and other uremic toxins in the rat. The Journal of pharmacology and experimental therapeutics 20021101
Interaction of the metal chelator 2,3-dimercapto-1-propanesulfonate with the rabbit multispecific organic anion transporter 1 (rbOAT1). Molecular pharmacology 20021101
The renal Na(+)-dependent dicarboxylate transporter, NaDC-3, translocates dimethyl- and disulfhydryl-compounds and contributes to renal heavy metal detoxification. Journal of the American Society of Nephrology : JASN 20021101
Effect of deep pentobarbital anesthesia on neurotransmitter metabolism in vivo: on the correlation of total glucose consumption with glutamatergic action. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20021101
The third activity for lysyl hydroxylase 3: galactosylation of hydroxylysyl residues in collagens in vitro. Matrix biology : journal of the International Society for Matrix Biology 20021101
II. Glutamine and glutamate. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20021101
Demonstration of pyruvate recycling in primary cultures of neocortical astrocytes but not in neurons. Neurochemical research 20021101
Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS-DA. FEBS letters 20021023
Cofactor binding to Escherichia coli D-3-phosphoglycerate dehydrogenase induces multiple conformations which alter effector binding. The Journal of biological chemistry 20021018
Selective inactivation of redox-sensitive mitochondrial enzymes during cardiac reperfusion. Archives of biochemistry and biophysics 20021015
Isolation and biochemical characterization of hypophosphite/2-oxoglutarate dioxygenase. A novel phosphorus-oxidizing enzyme from Psuedomonas stutzeri WM88. The Journal of biological chemistry 20021011
Urate/alpha-ketoglutarate exchange in avian basolateral membrane vesicles. American journal of physiology. Cell physiology 20021001
Facilitated diffusion of urate in avian brush-border membrane vesicles. American journal of physiology. Cell physiology 20021001
Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species. European journal of biochemistry 20021001
Inhibition of the alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase complexes by a putative aberrant metabolite of serotonin, tryptamine-4,5-dione. Chemical research in toxicology 20021001
Protective influences of alpha-ketoglutarate on lipid peroxidation and antioxidant status in ammonium acetate treated rats. Indian journal of experimental biology 20021001
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage. Nature 20020912
The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related. The Journal of biological chemistry 20020906
Mitochondrial substrate level phosphorylation is essential for growth of procyclic Trypanosoma brucei. The Journal of biological chemistry 20020906
Ca(2+) modulates respiratory and steroidogenic activities of human term placental mitochondria. Archives of biochemistry and biophysics 20020901
Mutant deoxynucleotide carrier is associated with congenital microcephaly. Nature genetics 20020901
The succinate mechanism of insulin release. Diabetes 20020901
A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology. Journal of molecular medicine (Berlin, Germany) 20020901
A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferases. Analytical biochemistry 20020901
Alpha-ketoglutarate-supplemented enteral nutrition: effects on postoperative nitrogen balance and muscle catabolism. Nutrition (Burbank, Los Angeles County, Calif.) 20020901
Effects of alpha-ketoglutarate on antioxidants and lipid peroxidation products in rats treated with ammonium acetate. Nutrition (Burbank, Los Angeles County, Calif.) 20020901
Goodbye sodium alpha-ketoglutarate? Nutrition (Burbank, Los Angeles County, Calif.) 20020901
Molecular analysis of the role of two aromatic aminotransferases and a broad-specificity aspartate aminotransferase in the aromatic amino acid metabolism of Pyrococcus furiosus. Archaea (Vancouver, B.C.) 20020901
A tormentor in the quest for plant p53-like proteins. FEBS letters 20020828
The anaplerotic substrate alanine stimulates acetate incorporation into glutamate and glutamine in rabbit kidney tubules. A (13)C NMR study. The Journal of biological chemistry 20020816
Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism. Biochemical pharmacology 20020815
The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits. The Journal of biological chemistry 20020809
Calcium modulates the ATP and ADP hydrolysis in human placental mitochondria. The international journal of biochemistry & cell biology 20020801
Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis. American journal of physiology. Endocrinology and metabolism 20020801
Functional expression and mutational analysis of flavonol synthase from Citrus unshiu. European journal of biochemistry 20020801
Role of organic acids in aluminum accumulation and plant growth in Melastoma malabathricum. Tree physiology 20020801
Decreased TCA cycle rate in the rat brain after acute 3-NP treatment measured by in vivo 1H-[13C] NMR spectroscopy. Journal of neurochemistry 20020801
Glutamate dehydrogenase activity: a major criterion for the selection of flavour-producing lactic acid bacteria strains. Antonie van Leeuwenhoek 20020801
Antioxidant alpha-keto-carboxylate pyruvate protects low-density lipoprotein and atherogenic macrophages. Free radical research 20020801
Absorption and metabolism of alpha-ketoglutarate in growing pigs. Journal of animal physiology and animal nutrition 20020801
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family. The Journal of biological chemistry 20020719
HIF-1alpha-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway. Biochemical and biophysical research communications 20020719
Structural studies on the synchronization of catalytic centers in glutamate synthase. The Journal of biological chemistry 20020705
Identification of a novel transporter for dicarboxylates and tricarboxylates in plant mitochondria. Bacterial expression, reconstitution, functional characterization, and tissue distribution. The Journal of biological chemistry 20020705
Characterization of bacterial homocitrate synthase involved in lysine biosynthesis. FEBS letters 20020703
Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice. Molecular pharmacology 20020701
Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK. European journal of biochemistry 20020701
Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. The American journal of psychiatry 20020701
Polymorphism of the vitamin D(3) receptor in patients with psoriasis. Archives of dermatological research 20020701
Cerebrospinal fluid levels of thiamine in patients with Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996) 20020701
Specific growth inhibition by acetate of an Escherichia coli strain expressing Era-dE, a dominant negative Era mutant. Journal of molecular microbiology and biotechnology 20020701
Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020701
Identifying and characterizing plastidic 2-oxoglutarate/malate and dicarboxylate transporters in Arabidopsis thaliana. Plant & cell physiology 20020701
Characterization of oxidative phosphorylation in the colorless chlorophyte Polytomella sp. Its mitochondrial respiratory chain lacks a plant-like alternative oxidase. Biochimica et biophysica acta 20020701
Exploring routes to stabilize a cationic pyridoxamine in an artificial transaminase: site-directed mutagenesis versus synthetic cofactors. Protein engineering 20020701
[TCA cycle, oxidative phosphorylation and uncoupling protein]. Nihon rinsho. Japanese journal of clinical medicine 20020701
Properties of the recombinant ferredoxin-dependent glutamate synthase of Synechocystis PCC6803. Comparison with the Azospirillum brasilense NADPH-dependent enzyme and its isolated alpha subunit. Biochemistry 20020625
Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity. The Journal of biological chemistry 20020621
The use of dioxygen by HIF prolyl hydroxylase (PHD1). Bioorganic & medicinal chemistry letters 20020617
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. Genes & development 20020615
Aspartate aminotransferase isotope exchange reactions: implications for glutamate/glutamine shuttle hypothesis. American journal of physiology. Cell physiology 20020601
Mechanisms used to dispose of progressively increasing alkali load in rats. American journal of physiology. Renal physiology 20020601
Characterization of rainbow trout branched-chain alpha-keto acid dehydrogenase complex: inter-domain segments of the E2 component affect the overall activity. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020601
Glutamine concentration and tissue exchange with intravenously administered alpha-ketoglutaric acid and ammonium: a dose-response study in the pig. Nutrition (Burbank, Los Angeles County, Calif.) 20020601
Decreased Rubisco activity leads to dramatic changes of nitrate metabolism, amino acid metabolism and the levels of phenylpropanoids and nicotine in tobacco antisense RBCS transformants. The Plant journal : for cell and molecular biology 20020601
Amino acid composition of bulk protein and salt relationships of selected enzymes of Salinibacter ruber, an extremely halophilic bacterium. Extremophiles : life under extreme conditions 20020601
A possible mouse model for spontaneous cholangitis: serological and histological characteristics of MRL/lpr mice. Pathology 20020601
Intensity of free radical processes and regulation of cytoplasmic NADP-isocitrate dehydrogenase in rat cardiomyocytes under normal and ischemic conditions. Biochemistry. Biokhimiia 20020601
Promising role of alpha-ketoglutarate in protecting against the lethal effects of cyanide. Human & experimental toxicology 20020601
Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine. Biochemistry 20020528
Cassette mutagenesis and photoaffinity labeling of adenine binding domain of ADP regulatory site within human glutamate dehydrogenase. Biochemistry 20020528
Identification of amino acids important for the catalytic activity of the collagen glucosyltransferase associated with the multifunctional lysyl hydroxylase 3 (LH3). The Journal of biological chemistry 20020524
Substrate recognition by 2-oxoacid:ferredoxin oxidoreductase from Sulfolobus sp. strain 7. Biochimica et biophysica acta 20020520
Nitrogen regulation in Saccharomyces cerevisiae. Gene 20020515
Direct interaction of the NifL regulatory protein with the GlnK signal transducer enables the Azotobacter vinelandii NifL-NifA regulatory system to respond to conditions replete for nitrogen. The Journal of biological chemistry 20020503
Mitochondrial dysfunction in acute hyperammonemia. Neurochemistry international 20020501
Non-invasive measurements of myocardial carbon metabolism using in vivo 13C NMR spectroscopy. NMR in biomedicine 20020501
Spectroscopic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: molecular mechanism and CO(2) activation in the biosynthesis of ethylene. Journal of the American Chemical Society 20020501
Crystallization and preliminary X-ray analysis of the full-size cubic core of pig 2-oxoglutarate dehydrogenase complex. Acta crystallographica. Section D, Biological crystallography 20020501
The novel protein phosphatase PphA from Synechocystis PCC 6803 controls dephosphorylation of the signalling protein PII. Molecular microbiology 20020501
Utilization of sterol carrier protein-2 by phytanoyl-CoA 2-hydroxylase in the peroxisomal alpha oxidation of phytanic acid. Chemistry & biology 20020501
GDH1 expression is regulated by GLN3, GCN4, and HAP4 under respiratory growth. Biochemical and biophysical research communications 20020426
Crystal structure of a clavaminate synthase-Fe(II)-2-oxoglutarate-substrate-NO complex: evidence for metal centered rearrangements. FEBS letters 20020424
X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates. Biochemistry 20020423
Carnitine biosynthesis in Neurospora crassa: identification of a cDNA coding for epsilon-N-trimethyllysine hydroxylase and its functional expression in Saccharomyces cerevisiae. FEMS microbiology letters 20020423
Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations. The Biochemical journal 20020401
Interaction of cytosolic and plastidic nitrogen metabolism in plants. Journal of experimental botany 20020401
Molecular and enzymatic analysis of ammonium assimilation in woody plants. Journal of experimental botany 20020401
Enzyme redundancy and the importance of 2-oxoglutarate in plant ammonium assimilation. Journal of experimental botany 20020401
Steps towards an integrated view of nitrogen metabolism. Journal of experimental botany 20020401
Skeletal muscle characteristics predict body fat gain in response to overfeeding in never-obese young men. Metabolism: clinical and experimental 20020401
Molecular and regulatory properties of leucoplast pyruvate kinase from Brassica napus (rapeseed) suspension cells. Archives of biochemistry and biophysics 20020401
Ischemic preconditioning improves mitochondrial tolerance to experimental calcium overload. The Journal of surgical research 20020401
Escherichia coli aconitases and oxidative stress: post-transcriptional regulation of sodA expression. Microbiology (Reading, England) 20020401
Photorespiration-dependent increases in phospho enolpyruvate carboxylase, isocitrate dehydrogenase and glutamate dehydrogenase in transformed tobacco plants deficient in ferredoxin-dependent glutamine-alpha-ketoglutarate aminotransferase. Planta 20020401
Characterization of isocitrate dehydrogenase from the green sulfur bacterium Chlorobium limicola. A carbon dioxide-fixing enzyme in the reductive tricarboxylic acid cycle. European journal of biochemistry 20020401
[Alpha-ketoglutarate dehydrogenase complex]. Nihon rinsho. Japanese journal of clinical medicine 20020401
[Alpha-ketoglutarate dehydrogenase deficiency]. Nihon rinsho. Japanese journal of clinical medicine 20020401
Temperature dependence of kinetic parameters for hyperthermophilic glutamate dehydrogenase from Aeropyrum pernix K1. Bioscience, biotechnology, and biochemistry 20020401
[Study on biochemical mechanism of citral damage to the A. flavasi's mitochondria]. Wei sheng wu xue bao = Acta microbiologica Sinica 20020401
Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase. The Journal of biological chemistry 20020322
Active site mutations of recombinant deacetoxycephalosporin C synthase. Biochemical and biophysical research communications 20020322
A novel five-subunit-type 2-oxoglutalate:ferredoxin oxidoreductases from Hydrogenobacter thermophilus TK-6. Biochemical and biophysical research communications 20020322
Oxidative stress increases internal calcium stores and reduces a key mitochondrial enzyme. Biochimica et biophysica acta 20020316
Aluminum citrate uptake by immortalized brain endothelial cells: implications for its blood-brain barrier transport. Brain research 20020315
In vitro and in vivo attenuation of experimental cyanide poisoning by alpha-ketoglutarate. Toxicology letters 20020310
Hydrogen turnover and subcellular compartmentation of hepatic [2-(13)C]glutamate and [3-(13)C]aspartate as detected by (13)C NMR. The Journal of biological chemistry 20020308
cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase. Genomics 20020301
Effects of ornithine 2-oxoglutarate on neutrophils in stressed rats: evidence for the involvement of nitric oxide and polyamines. Clinical science (London, England : 1979) 20020301
Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase. Diabetes 20020301
Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301
Glutamine: an anaplerotic precursor. Nutrition (Burbank, Los Angeles County, Calif.) 20020301
The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain. Nitric oxide : biology and chemistry 20020301
Phototrophic consortia: model systems for symbiotic interrelations between prokaryotes. Archives of microbiology 20020301
2-Oxoglutarate increases the binding affinity of the NtcA (nitrogen control) transcription factor for the Synechococcus glnA promoter. FEBS letters 20020213
UCP2-dependent proton leak in isolated mammalian mitochondria. The Journal of biological chemistry 20020208
The Rhizobium leguminosarum bv. viciae VF39 gamma-aminobutyrate (GABA) aminotransferase gene (gabT) is induced by GABA and highly expressed in bacteroids. Microbiology (Reading, England) 20020201
Mitochondrial dysfunction associated with neuronal death following status epilepticus in rat. Epilepsy research 20020201
Identification of the YMN-1 antigen protein and biochemical analyses of protein components in the mitochondrial nucleoid fraction of the yeast Saccharomyces cerevisiae. Protoplasma 20020201
Metabolic compartmentation in cortical synaptosomes: influence of glucose and preferential incorporation of endogenous glutamate into GABA. Neurochemical research 20020201
Structural basis of the dysfunctioning of human 2-oxo acid dehydrogenase complexes. Current medicinal chemistry 20020201
Oxygen sensors and angiogenesis. Seminars in cell & developmental biology 20020201
Plasma lysine concentration and availability of 2-ketoglutarate in liver mitochondria. Journal of inherited metabolic disease 20020201
High-yield actinorhodin production in fed-batch culture by a Streptomyces lividans strain overexpressing the pathway-specific activator gene actll-ORF4. Journal of industrial microbiology & biotechnology 20020201
Inhibition of aspartate aminotransferase by glycation in vitro under various conditions. Journal of enzyme inhibition and medicinal chemistry 20020201
A large outbreak of Legionnaires' disease at a flower show, the Netherlands, 1999. Emerging infectious diseases 20020101
Biosynthesis of anthraquinones in cell cultures of Cinchona 'Robusta' proceeds via the methylerythritol 4-phosphate pathway. Phytochemistry 20020101
Glutamine: clinical applications and mechanisms of action. Current opinion in clinical nutrition and metabolic care 20020101
Structure and mechanism of anthocyanidin synthase from Arabidopsis thaliana. Structure (London, England : 1993) 20020101
Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities. Journal of neurochemistry 20020101
Aminoadipate reductase gene: a new fungal-specific gene for comparative evolutionary analyses. BMC evolutionary biology 20020101
Enzymatic amplification by substrate recycling for alpha-ketoglutarate in conjunction with capillary electrophoresis. Journal of capillary electrophoresis and microchip technology 20020101
Essentiality of mitochondrial oxidative metabolism for photosynthesis: optimization of carbon assimilation and protection against photoinhibition. Critical reviews in biochemistry and molecular biology 20020101
[Different therapeutic approaches for chronic diffuse liver lesions using ornicetil, lactulose, etimizol and corinfar]. Likars'ka sprava 20020101
Gene discovery within the planctomycete division of the domain Bacteria using sequence tags from genomic DNA libraries. Genome biology 20020101
[Biologic properties of lipoic acid]. Postepy higieny i medycyny doswiadczalnej 20020101
Activity of enzymes involved in energy production in the small intestine during suckling-weaning transition of pigs. Biology of the neonate 20020101
Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex. Advances in enzyme regulation 20020101
[Metabolism of Yarrowia lipolytica grown on ethanol under conditions promoting the production of alpha-ketoglutaric and citric acids: a comparative study of the central metabolism enzymes]. Mikrobiologiia 20020101
Molecular characterization of the renal organic anion transporter 1. Cell biochemistry and biophysics 20020101
Effects of ornithine alpha-ketoglutarate on circulatory antioxidants and lipid peroxidation products in ammonium acetate treated rats. Annals of nutrition & metabolism 20020101
The complex fate of alpha-ketoacids. Annual review of plant biology 20020101
Effects of alpha-ketoglutarate on lipid peroxidation and antioxidant status during chronic ethanol administration in Wistar rats. Polish journal of pharmacology 20020101
Regulation of the production of polygalacturonase by Aspergillus niger. Folia microbiologica 20020101
Metabolic signaling between neurons and glial cells: a short review. Journal of physiology, Paris 20020101
[Exogenous L-arginine modulates mitochondrial and microsomal oxidation in acute and intermittent normobaric hypoxia]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20020101
Selective identification of new therapeutic targets of Mycobacterium tuberculosis by IVIAT approach. Tuberculosis (Edinburgh, Scotland) 20020101
Glucose metabolism, energetics, and function of rat hearts exposed to ischemic preconditioning and oxygenated cardioplegia. Journal of cardiac surgery 20020101
Mitochondria in Alzheimer's disease. International review of neurobiology 20020101
[A comparative study of the isocitrate dehydrogenases of Chlorobium limicola forma Chlorobium thiosulfatophilum and Rhodopseudomonas palustris]. Mikrobiologiia 20020101
Heart-specific genes revealed by expressed sequence tag (EST) sampling. Genome biology 20020101
The mitochondrial uncoupling proteins. Genome biology 20020101
Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology. Respiratory research 20020101
[Mitochondria respiration in developing sunflower seeds]. Izvestiia Akademii nauk. Seriia biologicheskaia 20020101
Transport of anionic drugs across the basolateral membrane of proximal S2 segments of the rabbit kidney. Inverse relationship between the affinity to the p-aminohippurate transport system and the transport rate. Arzneimittel-Forschung 20020101
[Regulation of oxidative phosphorylation by liver mitochondria receptors after adaptation by rats to periodic normal pressure and acute hypoxia]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101
[Effect of tricarboxylic acid cycle intermediates on nitric oxide system during acute hypoxia]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101
Ammonia assimilation in Klebsiella pneumoniae F-5-2 that can utilize ammonium and nitrate ions simultaneously: purification and characterization of glutamate dehydrogenase and glutamine synthetase. Journal of bioscience and bioengineering 20020101
The mitochondrial oxoglutarate carrier: cysteine-scanning mutagenesis of transmembrane domain IV and sensitivity of Cys mutants to sulfhydryl reagents. Biochemistry 20011225
Glutamate decreases pyruvate carboxylase activity and spares glucose as energy substrate in cultured cerebellar astrocytes. Journal of neuroscience research 20011215
Monitoring of alpha-ketoglutarate in a fermentation process using expanded bed enzyme reactors. Biosensors & bioelectronics 20011201
Suramin inhibits respiration and induces membrane permeability transition in isolated rat liver mitochondria. Toxicology 20011201
Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases. European journal of biochemistry 20011201
The acute effect of valproate on cerebral energy metabolism in mice. Epilepsy research 20011201
Chemopreventive efficacy of selenium against N-nitrosodiethylamine-induced hepatoma in albino rats. Cell biochemistry and function 20011201
Pyruvate carboxylation in neurons. Journal of neuroscience research 20011201
Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain. Journal of neuroscience research 20011201
Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy. Journal of neuroscience research 20011201
Alternative oxidase in durum wheat mitochondria. Activation by pyruvate, hydroxypyruvate and glyoxylate and physiological role. Plant & cell physiology 20011201
Expression of the 2,4-D degradative pathway of pJP4 in an alkaliphilic, moderately halophilic soda lake isolate, Halomonas sp. EF43. Extremophiles : life under extreme conditions 20011201
Selective loss of KGDHC-enriched neurons in Alzheimer temporal cortex: does mitochondrial variation contribute to selective vulnerability? Journal of molecular neuroscience : MN 20011201
[Study on the organic acids metabolism in Candida glycerolgenesis under different fermentation conditions]. Wei sheng wu xue bao = Acta microbiologica Sinica 20011201
A soybean plastid-targeted NADH-malate dehydrogenase: cloning and expression analyses. American journal of botany 20011201
Effect of DL-alpha-lipoic acid on mitochondrial enzymes in aged rats. Chemico-biological interactions 20011128
Effect of environmental and chemotactic stimuli on the activity of the Campylobacter jejuni flaA sigma(28) promoter. FEMS microbiology letters 20011127
NADP-glutamate dehydrogenase isoenzymes of Saccharomyces cerevisiae. Purification, kinetic properties, and physiological roles. The Journal of biological chemistry 20011123
Modelling mammary metabolism in the dairy cow to predict milk constituent yield, with emphasis on amino acid metabolism and milk protein production: model construction. Journal of theoretical biology 20011121
Analysis of conformationally restricted alpha-ketoglutarate analogues as substrates of dehydrogenases and aminotransferases. Analytical biochemistry 20011115
Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1. Molecular pharmacology 20011101
Crystallization and preliminary X-ray diffraction studies of monomeric isocitrate dehydrogenase by the MAD method using Mn atoms. Acta crystallographica. Section D, Biological crystallography 20011101
Role of a highly conserved YPITP motif in 2-oxoacid:ferredoxin oxidoreductase: heterologous expression of the gene from Sulfolobus sp.strain 7, and characterization of the recombinant and variant enzymes. European journal of biochemistry 20011101
Substrate-specific diffusion of select dicarboxylates through Chlamydia trachomatis PorB. Microbiology (Reading, England) 20011101
Characterization of the ornithine aminotransferase from Plasmodium falciparum. Molecular and biochemical parasitology 20011101
Perspectives on the biology of uncoupling protein (UCP) homologues. Biochemical Society transactions 20011101
Modulation of TCA cycle enzymes and aluminum stress in Pseudomonas fluorescens. Journal of inorganic biochemistry 20011101
The effect of high-intensity exhaustive exercise studied in isolated mitochondria from human skeletal muscle. Pflugers Archiv : European journal of physiology 20011101
Mechanism of inhibition of lysyl hydroxylase activity by the organophosphates malathion and malaoxon. Toxicology and applied pharmacology 20011101
Hydrogen-deuterium exchange at non-labile sites: a new reaction facet with broad implications for structural and dynamic determinations. Journal of the American Society for Mass Spectrometry 20011101
H+-ATPase defect in Corynebacterium glutamicum abolishes glutamic acid production with enhancement of glucose consumption rate. Applied microbiology and biotechnology 20011101
Cyanobacteria perceive nitrogen status by sensing intracellular 2-oxoglutarate levels. The Journal of biological chemistry 20011012
The inhibition of gluconeogenesis by chloroquine contributes to its hypoglycaemic action. European journal of pharmacology 20011012
A single gene produces mitochondrial, cytoplasmic, and peroxisomal NADP-dependent isocitrate dehydrogenase in Aspergillus nidulans. The Journal of biological chemistry 20011005
Metabolic consequences of altered phosphoenolpyruvate carboxykinase activity in Corynebacterium glutamicum reveal anaplerotic regulation mechanisms in vivo. Metabolic engineering 20011001
Contrasting fates for 6-alpha-methylpenicillin N upon oxidation by deacetoxycephalosporin C synthase (DAOCS) and deacetoxy/deacetylcephalosporin C synthase (DAOC/DACS). Bioorganic & medicinal chemistry letters 20010917
Molecular and Biochemical Characterization of Rat epsilon -N-Trimethyllysine Hydroxylase, the First Enzyme of Carnitine Biosynthesis. The Journal of biological chemistry 20010907
NMR indirect detection of glutamate to measure citric acid cycle flux in the isolated perfused mouse heart. FEBS letters 20010907
The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite. Bioorganic & medicinal chemistry letters 20010903
Mechanism of increased renal gene expression during metabolic acidosis. American journal of physiology. Renal physiology 20010901
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. American journal of physiology. Renal physiology 20010901
Structure-function analysis of phytanoyl-CoA 2-hydroxylase mutations causing Refsum's disease. Human molecular genetics 20010901
Conversion of amino acids into aroma compounds by cell-free extracts of Lactobacillus helveticus. Journal of applied microbiology 20010901
Effects of ADP on different inhibitory properties of brain glutamate dehydrogenase isoproteins by perphenazine. Biochimie 20010901
Alteration of the specificity of malate dehydrogenase by chemical modulation of an active site arginine. The Journal of biological chemistry 20010817
Investigations into biochemical changes due to diurnal variation and estrus cycle in female rats using high-resolution (1)H NMR spectroscopy of urine and pattern recognition. Analytical biochemistry 20010815
Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities. Journal of the American Chemical Society 20010801
Detection of antimitochondrial autoantibodies in immunofluorescent AMA-negative patients with primary biliary cirrhosis using recombinant autoantigens. Hepatology (Baltimore, Md.) 20010801
Intrahepatic amino acid and glucose metabolism in a D-galactosamine-induced rat liver failure model. Hepatology (Baltimore, Md.) 20010801
Lipoamide dehydrogenase from Corynebacterium glutamicum: molecular and physiological analysis of the lpd gene and characterization of the enzyme. Microbiology (Reading, England) 20010801
Metabonomic investigations into hydrazine toxicity in the rat. Chemical research in toxicology 20010801
Reaction mechanism from leucoanthocyanidin to anthocyanidin 3-glucoside, a key reaction for coloring in anthocyanin biosynthesis. The Journal of biological chemistry 20010713
Gas chromatographic-mass spectrometric screening for organic acidemias using dried urine filter paper: determination of alpha-ketoacids. Journal of chromatography. B, Biomedical sciences and applications 20010705
A mathematical model of compartmentalized neurotransmitter metabolism in the human brain. American journal of physiology. Endocrinology and metabolism 20010701
Biochemical properties of porcine white adipose tissue mitochondria and relevance to fatty acid oxidation. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010701
Comparative in vitro bacteriostatic and bactericidal activity of trovafloxacin, levofloxacin and moxifloxacin against clinical and environmental isolates of Legionella spp. International journal of antimicrobial agents 20010701
2-Oxoglutarate transport system in Staphylococcus aureus. Archives of microbiology 20010701
Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing. IUBMB life 20010701
Modulation of mitochondrial function by hydrogen peroxide. The Journal of biological chemistry 20010629
Ammonium in nervous tissue: transport across cell membranes, fluxes from neurons to glial cells, and role in signalling. Progress in neurobiology 20010601
Cassette mutagenesis of lysine 130 of human glutamate dehydrogenase. An essential residue in catalysis. European journal of biochemistry 20010601
Energetic determinants of tyrosine phosphorylation of focal adhesion proteins during hypoxia/reoxygenation of kidney proximal tubules. The American journal of pathology 20010601
Lactobacillus casei and Lactobacillus plantarum initiate catabolism of methionine by transamination. Journal of applied microbiology 20010601
Lipoic acid metabolism in Arabidopsis thaliana: cloning and characterization of a cDNA encoding lipoyltransferase. Plant & cell physiology 20010601
Molecular physiology of renal p-aminohippurate secretion. News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 20010601
Glutamine and alpha-ketoglutarate are metabolite signals involved in nitrate reductase gene transcription in untransformed and transformed tobacco plants deficient in ferredoxin-glutamine-alpha-ketoglutarate aminotransferase. Planta 20010601
Resonance Raman studies of the iron(II)--alpha-keto acid chromophore in model and enzyme complexes. Journal of the American Chemical Society 20010530
Alternative reactivity of an alpha-ketoglutarate-dependent iron(II) oxygenase: enzyme self-hydroxylation. Journal of the American Chemical Society 20010530
Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258. The Journal of biological chemistry 20010525
Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS). Journal of molecular biology 20010518
A GTP-dependent vertebrate-type phosphoenolpyruvate carboxykinase from Mycobacterium smegmatis. The Journal of biological chemistry 20010511
Determination of the midpoint potential of the FAD and FMN flavin cofactors and of the 3Fe-4S cluster of glutamate synthase. Biochemistry 20010508
Isolation of a family of organic anion transporters from human liver and kidney. Biochemical and biophysical research communications 20010504
Cloning and functional characterization of a high-affinity Na(+)/dicarboxylate cotransporter from mouse brain. American journal of physiology. Cell physiology 20010501
Inhibition of lysyl hydroxylase by malathion and malaoxon. Toxicology and applied pharmacology 20010501
Protection by thiols of the mitochondrial complexes from 4-hydroxy-2-nonenal. Free radical biology & medicine 20010501
13C isotopomer analysis of glucose and alanine metabolism reveals cytosolic pyruvate compartmentation as part of energy metabolism in astrocytes. Glia 20010501
[Mitochondrial DNA T to G mutation 8993 in Leigh encephalopathy and organic aciduria]. No to hattatsu = Brain and development 20010501
Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase. Cellular and molecular life sciences : CMLS 20010501
Production of beta-thujaplicin in Cupressus lusitanica suspension cultures fed with organic acids and monoterpenes. Bioscience, biotechnology, and biochemistry 20010501
[Effects of ammonia on cell metabolism in the culture of recombinant CHO cells]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20010501
Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme. Biochemistry 20010417
Recombinant tyrosine aminotransferase from Trypanosoma cruzi: structural characterization and site directed mutagenesis of a broad substrate specificity enzyme. Biochimica et biophysica acta 20010407
Glutamine protects mitochondrial structure and function in oxygen toxicity. American journal of physiology. Lung cellular and molecular physiology 20010401
Glutamine supplementation promotes anaplerosis but not oxidative energy delivery in human skeletal muscle. American journal of physiology. Endocrinology and metabolism 20010401
The effects of endurance training and exhaustive exercise on mitochondrial enzymes in tissues of the rat (Rattus norvegicus). Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010401
Adenoviral gene transfer restores lysyl hydroxylase activity in type VI Ehlers-Danlos syndrome. The Journal of investigative dermatology 20010401
Aspartate kinase 2. A candidate gene of a quantitative trait locus influencing free amino acid content in maize endosperm. Plant physiology 20010401
Complete genomic structure of mouse lysyl hydroxylase 2 and lysyl hydroxylase 3/collagen glucosyltransferase. Matrix biology : journal of the International Society for Matrix Biology 20010401
Increased levels of adenine nucleotides modify the interaction between starch synthesis and respiration when adenine is supplied to discs from growing potato tubers. Planta 20010401
Uridylylation of the PII protein from Herbaspirillum seropedicae. Canadian journal of microbiology 20010401
The genes for anabolic 2-oxoglutarate: ferredoxin oxidoreductase from Hydrogenobacter thermophilus TK-6. Biochemical and biophysical research communications 20010330
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation. Journal of molecular biology 20010323
Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location. The Journal of biological chemistry 20010316
Potent cytolytic response by a CD8+ CTL clone to multiple peptides from the same protein in association with an allogeneic class I MHC molecule. Journal of immunology (Baltimore, Md. : 1950) 20010301
Cloning and characterization of the gene encoding the glutamate dehydrogenase of Streptococcus suis serotype 2. Clinical and diagnostic laboratory immunology 20010301
Development of a stable-isotope dilution assay for gamma-aminobutyric acid (GABA) transaminase in isolated leukocytes and evidence that GABA and beta-alanine transaminases are identical. Clinical chemistry 20010301
Gene duplication in the diversification of secondary metabolism: tandem 2-oxoglutarate-dependent dioxygenases control glucosinolate biosynthesis in Arabidopsis. The Plant cell 20010301
Regulation of skeletal muscle amino acid metabolism during exercise. International journal of sport nutrition and exercise metabolism 20010301
Nitrogen shuttling between neurons and glial cells during glutamate synthesis. Journal of neurochemistry 20010301
P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin. Naunyn-Schmiedeberg's archives of pharmacology 20010301
Protective effect of Ninjin-yoei-to on damage to isolated hepatocytes following transient exposure to tert-butyl hydroperoxide. Japanese journal of pharmacology 20010301
Adenosine 5'-0-[S-(4-succinimidyl-benzophenone)thiophosphate]: a new photoaffinity label of the allosteric ADP site of bovine liver glutamate dehydrogenase. Biochemistry 20010213
A novel syndrome affecting multiple mitochondrial functions, located by microcell-mediated transfer to chromosome 2p14-2p13. American journal of human genetics 20010201
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2. Molecular pharmacology 20010201
Mitochondrial biogenesis during germination in maize embryos. Plant physiology 20010201
Chronic lamotrigine treatment increases rat hippocampal GABA shunt activity and elevates cerebral taurine levels. Epilepsy research 20010201
Spatial heterogeneity of energy turnover in the heart. Pflugers Archiv : European journal of physiology 20010201
Inhibitory effect of glycation on catalytic activity of alanine aminotransferase. Molecular and cellular biochemistry 20010201
[Effects of long-term physical training on age-related changes of energy transformation of mice heart mitochondria]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20010201
Mikimopine synthase (mis) gene on pRi1724. Gene 20010124
Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate. The Journal of biological chemistry 20010119
Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2-oxoglutarate due to depletion of the NADPH pool. Yeast (Chichester, England) 20010115
Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: contrast with the unique cold-induced mitochondrial carrier CGI-69. The Biochemical journal 20010115
Recognition of the lipoyl domain is the ultimate determinant of substrate channelling in the pyruvate dehydrogenase multienzyme complex. Journal of molecular biology 20010105
Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins. The Journal of pharmacology and experimental therapeutics 20010101
Biosynthesis of menaquinone (vitamin K2) and ubiquinone (coenzyme Q): a perspective on enzymatic mechanisms. Vitamins and hormones 20010101
Kynurenine aminotransferase I activity in human placenta. Placenta 20010101
Contribution of glutamate dehydrogenase to mitochondrial glutamate metabolism studied by (13)C and (31)P nuclear magnetic resonance. Journal of experimental botany 20010101
Glutamate dehydrogenase from liver of euthermic and hibernating Richardson's ground squirrels: evidence for two distinct enzyme forms. Biochemistry and cell biology = Biochimie et biologie cellulaire 20010101
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases. Genome biology 20010101
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy. Pharmacology 20010101
Lysine metabolism in higher plants. Amino acids 20010101
[Characteristics of NADP-dependent isocitrate dehydrogenase functioning in pea leaves during salt stress]. Izvestiia Akademii nauk. Seriia biologicheskaia 20010101
Effects of scopoletin and aflatoxin B1 on bovine hepatic mitochondrial respiratory complexes, 2: a-ketoglutarate cytochrome c and succinate cytochrome c reductases. Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101
[Metabolic characteristics of the Yarrowia lipolytica strain producing alpha-ketoglutaric and citric acids from ethanol and the effect of [NH4+] and [O2] on yeast respiration and biosynthesis]. Mikrobiologiia 20010101
Glutamate synthesis via photoreduction of NADP+ by photostable chlorophyllide coupled with polyethylene-glycol. Biotechnology and bioengineering 20010101
Tricarboxylic acid cycle enzymes of the ectomycorrhizal basidiomycete, Suillus bovinus. Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101
No association between DLST gene and Alzheimer's disease or Wernicke-Korsakoff syndrome. Neurobiology of aging 20010101
[New aerobic methyltrophic isolates from the Soda lakes of the southern Transbaikal]. Mikrobiologiia 20010101
[State of mitochondrial respiration and calcium capacity in livers of rats with different resistance to hypoxia after injections of L-arginine]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20010101
Purification and characterization of aspartate aminotransferase from developing embryos of the camel tick Hyalomma dromedarii. Experimental & applied acarology 20010101
[Alpha ketoglutarate dehydrogenase deficiency]. Ryoikibetsu shokogun shirizu 20010101
[Disorders of pyruvate metabolism and TCA cycle]. Ryoikibetsu shokogun shirizu 20010101
Effects of substrate structural analogues on the enzymatic activities of aspartate aminotransferase isoenzymes. Journal of enzyme inhibition 20010101
PKA, PKC, and AKAP localization in and around the neuromuscular junction. BMC neuroscience 20010101
Analysis of CHO cells metabolic redistribution in a glutamate-based defined medium in continuous culture. Biotechnology progress 20010101
Acute toxicity studies of alpha-ketoglutarate: a promising antidote for cyanide poisoning. Journal of applied toxicology : JAT 20010101
[The role of hyperlactatedehydrogenasemia in induction of metabolic disorders in the body]. Voprosy meditsinskoi khimii 20010101
Oxidative metabolites of 5-S-cysteinyldopamine inhibit the pyruvate dehydrogenase complex. Journal of neural transmission (Vienna, Austria : 1996) 20010101
Influence on Enterobacter cloacae metabolism, cell-surface hydrophobicity and motility of suprainhibitory concentrations of carbapenems. Folia microbiologica 20010101
The future of nutrition and wound healing. Journal of tissue viability 20010101
[Effect of L-arginine and the nitric oxide synthase blocker L-NNA on calcium capacity in rat liver mitochondria with differing resistance to hypoxia]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101
[Effect of L-arginine and N(omega)-nitro-L-arginine on oxidative phosphorylation and lipid peroxidation in rats with various tolerance to hypoxia under stressful conditions]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101
Inhibition of glutamine transport in rat brain mitochondria by some amino acids and tricarboxylic acid cycle intermediates. Neurochemical research 19990701
Biosynthesis of o-succinylbenzoic acid. I: Cell free synthesis of o-succinylbenzoic acid from isochorismic acid in enzyme preparations from vitamin K producing bacteria. Archives of biochemistry and biophysics 19870701
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