2-Oxopentanedioic acid
Title | Journal |
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Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics. | Scientific reports 20180101 |
Oncometabolites d- and l-2-Hydroxyglutarate Inhibit the AlkB Family DNA Repair Enzymes under Physiological Conditions. | Chemical research in toxicology 20170417 |
An Intestinal Farnesoid X Receptor-Ceramide Signaling Axis Modulates Hepatic Gluconeogenesis in Mice. | Diabetes 20170301 |
Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases. | Journal of hepatology 20160401 |
Tributyltin induces G2/M cell cycle arrest via NAD(+)-dependent isocitrate dehydrogenase in human embryonic carcinoma cells. | The Journal of toxicological sciences 20160401 |
Rotenone Stereospecifically Increases (S)-2-Hydroxyglutarate in SH-SY5Y Neuronal Cells. | Chemical research in toxicology 20150518 |
Selective inhibition of mutant isocitrate dehydrogenase 1 (IDH1) via disruption of a metal binding network by an allosteric small molecule. | The Journal of biological chemistry 20150109 |
Synthetic fermentation of bioactive non-ribosomal peptides without organisms, enzymes or reagents. | Nature chemistry 20141001 |
Metabolomic analysis of biochemical changes in the plasma and urine of collagen-induced arthritis in rats after treatment with Huang-Lian-Jie-Du-Tang. | Journal of ethnopharmacology 20140528 |
Activity of trypsin-like enzymes and gelatinases in rats with doxorubicin cardiomyopathy. | Ukrainian biochemical journal 20140101 |
Manipulation of the HIF-Vegf pathway rescues methyl tert-butyl ether (MTBE)-induced vascular lesions. | Toxicology and applied pharmacology 20131215 |
Screening β-arrestin recruitment for the identification of natural ligands for orphan G-protein-coupled receptors. | Journal of biomolecular screening 20130601 |
Cofactor balance by nicotinamide nucleotide transhydrogenase (NNT) coordinates reductive carboxylation and glucose catabolism in the tricarboxylic acid (TCA) cycle. | The Journal of biological chemistry 20130503 |
(-) Epicatechin attenuates mitochondrial damage by enhancing mitochondrial multi-marker enzymes, adenosine triphosphate and lowering calcium in isoproterenol induced myocardial infarcted rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130301 |
Development of a satisfactory and general continuous assay for aminotransferases by coupling with (R)-2-hydroxyglutarate dehydrogenase. | Analytical biochemistry 20121215 |
The enzymology of alanine aminotransferase (AlaAT) isoforms from Hordeum vulgare and other organisms, and the HvAlaAT crystal structure. | Archives of biochemistry and biophysics 20121201 |
5-Hydroxymethylcytosine--the elusive epigenetic mark in mammalian DNA. | Chemical Society reviews 20121107 |
The role of glutamine synthetase and glutamate dehydrogenase in cerebral ammonia homeostasis. | Neurochemical research 20121101 |
Formation of ethyl acetate by Kluyveromyces marxianus on whey during aerobic batch and chemostat cultivation at iron limitation. | Applied microbiology and biotechnology 20121101 |
α-Ketoglutaric acid production by Yarrowia lipolytica and its regulation. | Applied microbiology and biotechnology 20121101 |
Selective stabilization of HIF-1α in renal tubular cells by 2-oxoglutarate analogues. | The American journal of pathology 20121101 |
Ameliorative potential of alpha-ketoglutaric acid (AKG) on acute lung injuries induced by ammonia inhalation in rats. | Experimental lung research 20121101 |
Reduction of Na+, K+-ATPase activity and expression in cerebral cortex of glutaryl-CoA dehydrogenase deficient mice: a possible mechanism for brain injury in glutaric aciduria type I. | Molecular genetics and metabolism 20121101 |
Remodulation of central carbon metabolic pathway in response to arsenite exposure in Rhodococcus sp. strain NAU-1. | Microbial biotechnology 20121101 |
Enhanced α-ketoglutarate production in Yarrowia lipolytica WSH-Z06 by alteration of the acetyl-CoA metabolism. | Journal of biotechnology 20121031 |
Development of cell-active N6-methyladenosine RNA demethylase FTO inhibitor. | Journal of the American Chemical Society 20121031 |
The α-ketoglutarate/Fe(II)-dependent dioxygenase VldW is responsible for the formation of validamycin B. | Chembiochem : a European journal of chemical biology 20121015 |
IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives. | Clinical cancer research : an official journal of the American Association for Cancer Research 20121015 |
4-Hydroxy-2-oxoglutarate aldolase inactivity in primary hyperoxaluria type 3 and glyoxylate reductase inhibition. | Biochimica et biophysica acta 20121001 |
Whole genome expression profile in neuroblastoma cells exposed to 1-methyl-4-phenylpyridine. | Neurotoxicology 20121001 |
Biochemical characterization and kinetic properties of alanine aminotransferase homologues partially purified from wheat (Triticum aestivum L.). | Phytochemistry 20121001 |
α-Ketoglutarate-related inhibitors of HIF prolyl hydroxylases are substrates of renal organic anion transporters 1 (OAT1) and 4 (OAT4). | Pflugers Archiv : European journal of physiology 20121001 |
Characterization of the fungal gibberellin desaturase as a 2-oxoglutarate-dependent dioxygenase and its utilization for enhancing plant growth. | Plant physiology 20121001 |
IDH mutations in acute myeloid leukemia. | Human pathology 20121001 |
Immobilization of a mediator onto carbon cloth electrode and employment of the modified electrode to an electroenzymatic bioreactor. | Journal of microbiology and biotechnology 20121001 |
Identification and characterization of D-hydroxyproline dehydrogenase and Delta1-pyrroline-4-hydroxy-2-carboxylate deaminase involved in novel L-hydroxyproline metabolism of bacteria: metabolic convergent evolution. | The Journal of biological chemistry 20120921 |
siRNA knock down of glutamate dehydrogenase in astrocytes affects glutamate metabolism leading to extensive accumulation of the neuroactive amino acids glutamate and aspartate. | Neurochemistry international 20120901 |
Marked reduction of Na(+), K(+)-ATPase and creatine kinase activities induced by acute lysine administration in glutaryl-CoA dehydrogenase deficient mice. | Molecular genetics and metabolism 20120901 |
Valine but not leucine or isoleucine supports neurotransmitter glutamate synthesis during synaptic activity in cultured cerebellar neurons. | Journal of neuroscience research 20120901 |
Comparative enzymology of (2S,4R)4-fluoroglutamine and (2S,4R)4-fluoroglutamate. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20120901 |
Ion-exclusion chromatography determination of organic acid in uridine 5'-monophosphate fermentation broth. | Journal of chromatographic science 20120901 |
Unusual cyanobacterial TCA cycles: not broken just different. | Trends in plant science 20120901 |
The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology. | Neurochemistry international 20120901 |
Energy metabolism in cancer cells: how to explain the Warburg and Crabtree effects? | Medical hypotheses 20120901 |
IDH1 mutations inhibit multiple α-ketoglutarate-dependent dioxygenase activities in astroglioma. | Journal of neuro-oncology 20120901 |
Control of hydroxyproline catabolism in Sinorhizobium meliloti. | Molecular microbiology 20120901 |
Expression, purification, crystallization and preliminary X-ray analysis of a novel N-substituted branched-chain L-amino-acid dioxygenase from Burkholderia ambifaria AMMD. | Acta crystallographica. Section F, Structural biology and crystallization communications 20120901 |
Inverse solvent isotope effects demonstrate slow aquo release from hypoxia inducible factor-prolyl hydroxylase (PHD2). | Biochemistry 20120821 |
Structural determinants of the β-selectivity of a bacterial aminotransferase. | The Journal of biological chemistry 20120817 |
Glutaminolysis activates Rag-mTORC1 signaling. | Molecular cell 20120810 |
Metabolomic analysis of biochemical changes in the plasma and urine of first-episode neuroleptic-naïve schizophrenia patients after treatment with risperidone. | Journal of proteome research 20120803 |
Uridylylation of Herbaspirillum seropedicae GlnB and GlnK proteins is differentially affected by ATP, ADP and 2-oxoglutarate in vitro. | Archives of microbiology 20120801 |
Ménage à trois: the role of neurotransmitters in the energy metabolism of astrocytes, glutamatergic, and GABAergic neurons. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120801 |
Isocitrate dehydrogenase 1 is downregulated during early skin tumorigenesis which can be inhibited by overexpression of manganese superoxide dismutase. | Cancer science 20120801 |
Variation of the by-product spectrum during α-ketoglutaric acid production from raw glycerol by overexpression of fumarase and pyruvate carboxylase genes in Yarrowia lipolytica. | Applied microbiology and biotechnology 20120801 |
Regioselectivity of substrate hydroxylation versus halogenation by a nonheme iron(IV)-oxo complex: possibility of rearrangement pathways. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120801 |
Lipoic acid metabolism of Plasmodium--a suitable drug target. | Current pharmaceutical design 20120801 |
Individual maize chromosomes in the C(3) plant oat can increase bundle sheath cell size and vein density. | Plant physiology 20120801 |
Screening chelating inhibitors of HIF-prolyl hydroxylase domain 2 (PHD2) and factor inhibiting HIF (FIH). | Journal of inorganic biochemistry 20120801 |
1-Aminocyclopropane-1-carboxylic acid oxidase: insight into cofactor binding from experimental and theoretical studies. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120801 |
γ-Butyrobetaine hydroxylase catalyses a Stevens type rearrangement. | Bioorganic & medicinal chemistry letters 20120801 |
An engineered PII protein variant that senses a novel ligand: atomic resolution structure of the complex with citrate. | Acta crystallographica. Section D, Biological crystallography 20120801 |
Association of a multi-synthetase complex with translating ribosomes in the archaeon Thermococcus kodakarensis. | FEBS letters 20120730 |
Structural insights into the catalytic active site and activity of human Nit2/ω-amidase: kinetic assay and molecular dynamics simulation. | The Journal of biological chemistry 20120727 |
Plant growth regulator daminozide is a selective inhibitor of human KDM2/7 histone demethylases. | Journal of medicinal chemistry 20120726 |
The Skp1 protein from Toxoplasma is modified by a cytoplasmic prolyl 4-hydroxylase associated with oxygen sensing in the social amoeba Dictyostelium. | The Journal of biological chemistry 20120720 |
Alterations in histone H4 lysine 20 methylation: implications for cancer detection and prevention. | Antioxidants & redox signaling 20120715 |
Functional characterization of recombinant hyoscyamine 6β-hydroxylase from Atropa belladonna. | Bioorganic & medicinal chemistry 20120715 |
Free glucosylglycerate is a novel marker of nitrogen stress in Mycobacterium smegmatis. | Journal of proteome research 20120706 |
Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics? | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120701 |
Sample preparation method to minimize chemical shift variability for NMR-based urinary metabonomics of genetically hypertensive rats. | Journal of pharmaceutical and biomedical analysis 20120701 |
Coelomic fluid: a complimentary biological medium to assess sub-lethal endosulfan exposure using ¹H NMR-based earthworm metabolomics. | Ecotoxicology (London, England) 20120701 |
Adverse effects of α-ketoglutarate/malate in a rat model of acute kidney injury. | American journal of physiology. Renal physiology 20120701 |
High-level exogenous glutamic acid-independent production of poly-(γ-glutamic acid) with organic acid addition in a new isolated Bacillus subtilis C10. | Bioresource technology 20120701 |
Application of 1H-NMR-based metabolomics for detecting injury induced by long-term microwave exposure in Wistar rats' urine. | Analytical and bioanalytical chemistry 20120701 |
Lysyl hydroxylase 3-mediated glucosylation in type I collagen: molecular loci and biological significance. | The Journal of biological chemistry 20120629 |
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. | Genes & development 20120615 |
Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells. | Amino acids 20120601 |
Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation. | Neurobiology of aging 20120601 |
Differential regulation of alanine aminotransferase homologues by abiotic stresses in wheat (Triticum aestivum L.) seedlings. | Plant cell reports 20120601 |
Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate. | The Biochemical journal 20120601 |
Influence of the ADP/ATP ratio, 2-oxoglutarate and divalent ions on Azospirillum brasilense PII protein signalling. | Microbiology (Reading, England) 20120601 |
Enhanced α-ketoglutaric acid production in Yarrowia lipolytica WSH-Z06 by an improved integrated fed-batch strategy. | Bioresource technology 20120601 |
Methylmalonate impairs mitochondrial respiration supported by NADH-linked substrates: involvement of mitochondrial glutamate metabolism. | Journal of neuroscience research 20120601 |
Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae. | Archives of biochemistry and biophysics 20120601 |
Two-component signal transduction in Corynebacterium glutamicum and other corynebacteria: on the way towards stimuli and targets. | Applied microbiology and biotechnology 20120601 |
Metabonomic responses in rat urine following subacute exposure to propoxur. | International journal of toxicology 20120601 |
Age-dependent reductions in mitochondrial respiration are exacerbated by calcium in the female rat heart. | Gender medicine 20120601 |
Metabolic profiling of Staphylococcus aureus cultivated under aerobic and anaerobic conditions with (1)H NMR-based nontargeted analysis. | Canadian journal of microbiology 20120601 |
The impact of thiamine treatment in the diabetes mellitus. | Journal of clinical medicine research 20120601 |
Antisense inhibition of the 2-oxoglutarate dehydrogenase complex in tomato demonstrates its importance for plant respiration and during leaf senescence and fruit maturation. | The Plant cell 20120601 |
Identification of Legionella rubrilucens isolated from a hot spring for foot-soaking in Niigata, Japan. | Biocontrol science 20120601 |
Genetic evidence for bacterial chemolithoautotrophy based on the reductive tricarboxylic acid cycle in groundwater systems. | Microbes and environments 20120601 |
Electronic structure analysis of the oxygen-activation mechanism by Fe(II)- and α-ketoglutarate (αKG)-dependent dioxygenases. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120521 |
Characterization of a novel Agrobacterium tumefaciens galactarolactone cycloisomerase enzyme for direct conversion of D-galactarolactone to 3-deoxy-2-keto-L-threo-hexarate. | The Journal of biological chemistry 20120518 |
Tellurite-exposed Escherichia coli exhibits increased intracellular α-ketoglutarate. | Biochemical and biophysical research communications 20120518 |
Thiamine and Parkinson's disease. | Journal of the neurological sciences 20120515 |
The hydroxylation activity of Jmjd6 is required for its homo-oligomerization. | Journal of cellular biochemistry 20120501 |
Autocatalysed oxidative modifications to 2-oxoglutarate dependent oxygenases. | The FEBS journal 20120501 |
Characterization of a Trypanosoma brucei Alkb homolog capable of repairing alkylated DNA. | Experimental parasitology 20120501 |
Alpha-ketoglutarate (AKG) inhibits proliferation of colon adenocarcinoma cells in normoxic conditions. | Scandinavian journal of gastroenterology 20120501 |
Alterations of glucose metabolism in Escherichia coli mutants defective in respiratory-chain enzymes. | Journal of biotechnology 20120430 |
Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation. | The Journal of biological chemistry 20120427 |
[Functional difference of malate-aspartate shuttle system in liver between plateau zokor (Myospalax baileyi) and plateau pika (Ochotona curzoniae)]. | Sheng li xue bao : [Acta physiologica Sinica] 20120425 |
Metabolism of SO₂ binding compounds by Oenococcus oeni during and after malolactic fermentation in white wine. | International journal of food microbiology 20120416 |
Nuclear magnetic resonance-based metabolomics for prediction of gastric damage induced by indomethacin in rats. | Analytica chimica acta 20120413 |
Mechanistic studies on the application of DNA aptamers as inhibitors of 2-oxoglutarate-dependent oxygenases. | Journal of medicinal chemistry 20120412 |
Description of Anaerobaculum hydrogeniformans sp. nov., an anaerobe that produces hydrogen from glucose, and emended description of the genus Anaerobaculum. | International journal of systematic and evolutionary microbiology 20120401 |
Rapid detection of gene mutations responsible for non-syndromic aortic aneurysm and dissection using two different methods: resequencing microarray technology and next-generation sequencing. | Human genetics 20120401 |
Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors. | Molecular biology reports 20120401 |
A metabonomic study of biochemical changes characteristic of genetically hypertensive rats based on (1)H NMR spectroscopic urinalysis. | Hypertension research : official journal of the Japanese Society of Hypertension 20120401 |
Two alanine aminotranferases link mitochondrial glycolate oxidation to the major photorespiratory pathway in Arabidopsis and rice. | Journal of experimental botany 20120401 |
Translatome and metabolome effects triggered by gibberellins during rosette growth in Arabidopsis. | Journal of experimental botany 20120401 |
Synaptic vesicles are capable of synthesizing the VGLUT substrate glutamate from α-ketoglutarate for vesicular loading. | Journal of neurochemistry 20120401 |
Transcriptional response of susceptible and tolerant citrus to infection with Candidatus Liberibacter asiaticus. | Plant science : an international journal of experimental plant biology 20120401 |
The perinatal transition of the circulating metabolome in a nonhuman primate. | Pediatric research 20120401 |
[Regulatory mechanisms of novel lysine biosynthesis in thermophile]. | Seikagaku. The Journal of Japanese Biochemical Society 20120401 |
Microsomal glutathione transferase 1 protects against toxicity induced by silica nanoparticles but not by zinc oxide nanoparticles. | ACS nano 20120327 |
Complete genome sequence of Halopiger xanaduensis type strain (SH-6(T)). | Standards in genomic sciences 20120319 |
The structure and allosteric regulation of mammalian glutamate dehydrogenase. | Archives of biochemistry and biophysics 20120315 |
Functional characterization of aromatic amino acid aminotransferase involved in 2-phenylethanol biosynthesis in isolated rose petal protoplasts. | Journal of plant physiology 20120315 |
[Construction of cDNA library of Aspergillus niger H1 and screening of phosphate-dissolving related gene]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20120304 |
Isolation, characterization, and function analysis of a flavonol synthase gene from Ginkgo biloba. | Molecular biology reports 20120301 |
Transcriptional regulation of neurodevelopmental and metabolic pathways by NPAS3. | Molecular psychiatry 20120301 |
Mitochondrial ATP synthase: architecture, function and pathology. | Journal of inherited metabolic disease 20120301 |
IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F. | Leukemia 20120301 |
Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization. | Molecular & cellular proteomics : MCP 20120301 |
Effects of valproate on glutamate metabolism in rat brain slices: a (13)C NMR study. | Epilepsy research 20120301 |
The pleiotropic effects of erythropoietin in infection and inflammation. | Microbes and infection 20120301 |
Functional genomic analysis unravels a metabolic-inflammatory interplay in adrenoleukodystrophy. | Human molecular genetics 20120301 |
Barley grains, deficient in cytosolic small subunit of ADP-glucose pyrophosphorylase, reveal coordinate adjustment of C:N metabolism mediated by an overlapping metabolic-hormonal control. | The Plant journal : for cell and molecular biology 20120301 |
Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9. | Biotechnology letters 20120301 |
Impact of carbon dioxide enrichment on the responses of maize leaf transcripts and metabolites to water stress. | Physiologia plantarum 20120301 |
Deposition of ammonium and nitrate in the roots of maize seedlings supplied with different nitrogen salts. | Journal of experimental botany 20120301 |
The Fe(II)/α-ketoglutarate-dependent taurine dioxygenases from Pseudomonas putida and Escherichia coli are tetramers. | The FEBS journal 20120301 |
Disruption of genes for the enhanced biosynthesis of α-ketoglutarate in Corynebacterium glutamicum. | Canadian journal of microbiology 20120301 |
Urinary metabonomic study using a CUMS rat model of depression. | Magnetic resonance in chemistry : MRC 20120301 |
Insulin/IGF-1 and hypoxia signaling act in concert to regulate iron homeostasis in Caenorhabditis elegans. | PLoS genetics 20120301 |
Synchronized ATP oscillations have a critical role in prechondrogenic condensation during chondrogenesis. | Cell death & disease 20120301 |
System-level insights into yeast metabolism by thermodynamic analysis of elementary flux modes. | PLoS computational biology 20120301 |
Crystallization and preliminary X-ray studies of an electron-transfer complex of ferredoxin and ferredoxin-dependent glutamate synthase from the cyanobacterium Leptolyngbya boryana. | Acta crystallographica. Section F, Structural biology and crystallization communications 20120301 |
The influence of homocysteine and oxidative stress on pregnancy outcome. | Journal of medicine and life 20120222 |
Production of 3-hydroxypropionic acid via malonyl-CoA pathway using recombinant Escherichia coli strains. | Journal of biotechnology 20120220 |
Malate-aspartate shuttle and exogenous NADH/cytochrome c electron transport pathway as two independent cytosolic reducing equivalent transfer systems. | Archives of biochemistry and biophysics 20120215 |
IDH mutation impairs histone demethylation and results in a block to cell differentiation. | Nature 20120215 |
Linking of 2-oxoglutarate and substrate binding sites enables potent and highly selective inhibition of JmjC histone demethylases. | Angewandte Chemie (International ed. in English) 20120213 |
Characterization of central carbon metabolism of Streptococcus pneumoniae by isotopologue profiling. | The Journal of biological chemistry 20120203 |
Lysyl hydroxylase 3 is secreted from cells by two pathways. | Journal of cellular physiology 20120201 |
Low oxygen concentrations impair tissue development in tissue-engineered cardiovascular constructs. | Tissue engineering. Part A 20120201 |
Development of a non-targeted metabolomics method to investigate urine in a rat model of polycystic kidney disease. | Nephrology (Carlton, Vic.) 20120201 |
Postnatal administration of 2-oxoglutaric acid improves the intestinal barrier affected by the prenatal action of dexamethasone in pigs. | Nutrition (Burbank, Los Angeles County, Calif.) 20120201 |
Crystal structure of NAD+-dependent Peptoniphilus asaccharolyticus glutamate dehydrogenase reveals determinants of cofactor specificity. | Journal of structural biology 20120201 |
Precursors and inhibitors of hydrogen sulfide synthesis affect acute hypoxic pulmonary vasoconstriction in the intact lung. | Journal of applied physiology (Bethesda, Md. : 1985) 20120201 |
Taenia crassiceps: host treatment alters glycolisis and tricarboxilic acid cycle in cysticerci. | Experimental parasitology 20120201 |
Immunodetection of cyclooxygenase-2 (COX-2) is restricted to tissue macrophages in normal rat liver and to recruited mononuclear phagocytes in liver injury and cholangiocarcinoma. | Histochemistry and cell biology 20120201 |
Silencing of flavanone-3-hydroxylase in apple (Malus × domestica Borkh.) leads to accumulation of flavanones, but not to reduced fire blight susceptibility. | Plant physiology and biochemistry : PPB 20120201 |
Changes in mitochondrial glutathione levels and protein thiol oxidation in ∆yfh1 yeast cells and the lymphoblasts of patients with Friedreich's ataxia. | Biochimica et biophysica acta 20120201 |
IDH2 mutations are frequent in angioimmunoblastic T-cell lymphoma. | Blood 20120201 |
Proteome changes in tomato fruits prior to visible symptoms of chilling injury are linked to defensive mechanisms, uncoupling of photosynthetic processes and protein degradation machinery. | Plant & cell physiology 20120201 |
Integrating flux balance analysis into kinetic models to decipher the dynamic metabolism of Shewanella oneidensis MR-1. | PLoS computational biology 20120201 |
Metabolism and regulation of glycerolipids in the yeast Saccharomyces cerevisiae. | Genetics 20120201 |
Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae. | Biochemistry 20120131 |
Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione. | Free radical biology & medicine 20120115 |
The effect of varying carboxylate ligation on the electronic environment of N2O(x) (x = 1-3) nonheme iron: a DFT analysis. | Dalton transactions (Cambridge, England : 2003) 20120114 |
Structural and kinetic isotope effect studies of nicotinamidase (Pnc1) from Saccharomyces cerevisiae. | Biochemistry 20120110 |
The effects of oxaloacetate on hydrogen peroxide generation from ascorbate and epigallocatechin gallate in cell culture media: potential for altering cell metabolism. | Biochemical and biophysical research communications 20120106 |
Divergence and convergence in enzyme evolution. | The Journal of biological chemistry 20120102 |
Enzymology of the branched-chain amino acid oxidation disorders: the valine pathway. | Journal of inherited metabolic disease 20120101 |
Advances and challenges in the treatment of branched-chain amino/keto acid metabolic defects. | Journal of inherited metabolic disease 20120101 |
Methylophilus glucosoxydans sp. nov., a restricted facultative methylotroph from rice rhizosphere. | International journal of systematic and evolutionary microbiology 20120101 |
Metabolic control and regulation of the tricarboxylic acid cycle in photosynthetic and heterotrophic plant tissues. | Plant, cell & environment 20120101 |
The roles of phosphate and the phosphate carrier in the mitochondrial permeability transition pore. | Mitochondrion 20120101 |
Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry. | Brain pathology (Zurich, Switzerland) 20120101 |
Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy. | Advances in hematology 20120101 |
Enabling lead discovery for histone lysine demethylases by high-throughput RapidFire mass spectrometry. | Journal of biomolecular screening 20120101 |
The applications and obstacles of metabonomics in traditional chinese medicine. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Proteomic analysis of mitochondria in APOE transgenic mice and in response to an ischemic challenge. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20120101 |
Respiration characteristics of mitochondria in parental and giant transformed cells of the murine Nemeth-Kellner lymphoma. | Cell biology international 20120101 |
Pathological features of new animal models for primary biliary cirrhosis. | International journal of hepatology 20120101 |
Cloning and characterization of chicken fat mass and obesity associated (Fto) gene: fasting affects Fto expression. | Domestic animal endocrinology 20120101 |
The role of glutamate dehydrogenase in mammalian ammonia metabolism. | Neurotoxicity research 20120101 |
Altered cancer cell metabolism in gliomas with mutant IDH1 or IDH2. | Current opinion in oncology 20120101 |
A novel homozygous 5 bp deletion in FKBP10 causes clinically Bruck syndrome in an Indonesian patient. | European journal of medical genetics 20120101 |
PLOD2 induced under hypoxia is a novel prognostic factor for hepatocellular carcinoma after curative resection. | Liver international : official journal of the International Association for the Study of the Liver 20120101 |
Wild-type MIC distribution and epidemiological cut-off values in clinical Legionella pneumophila serogroup 1 isolates. | Diagnostic microbiology and infectious disease 20120101 |
A novel, simple, and sensitive colorimetric method to determine aromatic amino acid aminotransferase activity using the Salkowski reagent. | Folia microbiologica 20120101 |
Combined inactivation of the Clostridium cellulolyticum lactate and malate dehydrogenase genes substantially increases ethanol yield from cellulose and switchgrass fermentations. | Biotechnology for biofuels 20120101 |
The upregulation of thiamine (vitamin B1) biosynthesis in Arabidopsis thaliana seedlings under salt and osmotic stress conditions is mediated by abscisic acid at the early stages of this stress response. | BMC plant biology 20120101 |
Glutaminase immunoreactivity and enzyme activity is increased in the rat dorsal root ganglion following peripheral inflammation. | Pain research and treatment 20120101 |
The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia. | PloS one 20120101 |
Genomic characterization of the Taylorella genus. | PloS one 20120101 |
Cancer metabolism: current perspectives and future directions. | Cell death & disease 20120101 |
Identification of immunogenic proteins of Waddlia chondrophila. | PloS one 20120101 |
Decoding key nodes in the metabolism of cancer cells: sugar & spice and all things nice. | F1000 biology reports 20120101 |
Proteomic analysis of aortae from human lipoprotein(a) transgenic mice shows an early metabolic response independent of atherosclerosis. | PloS one 20120101 |
Comparative metaproteomics and diversity analysis of human intestinal microbiota testifies for its temporal stability and expression of core functions. | PloS one 20120101 |
Caenorhabditis elegans battling starvation stress: low levels of ethanol prolong lifespan in L1 larvae. | PloS one 20120101 |
Novel AlkB dioxygenases--alternative models for in silico and in vivo studies. | PloS one 20120101 |
D-Lactate altered mitochondrial energy production in rat brain and heart but not liver. | Nutrition & metabolism 20120101 |
The diversity of cyanobacterial metabolism: genome analysis of multiple phototrophic microorganisms. | BMC genomics 20120101 |
Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. | BMC genomics 20120101 |
Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction. | BMC microbiology 20120101 |
Brain insulin resistance and deficiency as therapeutic targets in Alzheimer's disease. | Current Alzheimer research 20120101 |
Protective effect of morin on cardiac mitochondrial function during isoproterenol-induced myocardial infarction in male Wistar rats. | Redox report : communications in free radical research 20120101 |
Energetics based spike generation of a single neuron: simulation results and analysis. | Frontiers in neuroenergetics 20120101 |
Toward a Systemic Understanding of Listeria monocytogenes Metabolism during Infection. | Frontiers in microbiology 20120101 |
Creatine protects against excitoxicity in an in vitro model of neurodegeneration. | PloS one 20120101 |
Transcriptomic analysis of toxoplasma development reveals many novel functions and structures specific to sporozoites and oocysts. | PloS one 20120101 |
HIF-independent regulation of thioredoxin reductase 1 contributes to the high levels of reactive oxygen species induced by hypoxia. | PloS one 20120101 |
Tet2 disruption leads to enhanced self-renewal and altered differentiation of fetal liver hematopoietic stem cells. | Scientific reports 20120101 |
Reconstruction and analysis of a genome-scale metabolic model for Scheffersomyces stipitis. | Microbial cell factories 20120101 |
Indy mutants: live long and prosper. | Frontiers in genetics 20120101 |
High CO2 and silicate limitation synergistically increase the toxicity of Pseudo-nitzschia fraudulenta. | PloS one 20120101 |
Zinc oxide nanoparticles cause nephrotoxicity and kidney metabolism alterations in rats. | Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101 |
Dynamic modelling under uncertainty: the case of Trypanosoma brucei energy metabolism. | PLoS computational biology 20120101 |
Proteomic analysis of Ketogulonicigenium vulgare under glutathione reveals high demand for thiamin transport and antioxidant protection. | PloS one 20120101 |
γ-Aminobutyric acid transporter 2 mediates the hepatic uptake of guanidinoacetate, the creatine biosynthetic precursor, in rats. | PloS one 20120101 |
Novel model of neuronal bioenergetics: postsynaptic utilization of glucose but not lactate correlates positively with Ca2+ signalling in cultured mouse glutamatergic neurons. | ASN neuro 20120101 |
Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients. | Journal of hematology & oncology 20120101 |
Differential Expression ESTs Associated with Fluorosis in Rats Liver. | Comparative and functional genomics 20120101 |
Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain. | Microbial cell factories 20120101 |
eIF2α kinases regulate development through the BzpR transcription factor in Dictyostelium discoideum. | PloS one 20120101 |
Sirtuins as regulators of the yeast metabolic network. | Frontiers in pharmacology 20120101 |
Iron utilization in marine cyanobacteria and eukaryotic algae. | Frontiers in microbiology 20120101 |
Hypoxia reduces arylsulfatase B activity and silencing arylsulfatase B replicates and mediates the effects of hypoxia. | PloS one 20120101 |
Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. | PloS one 20120101 |
The metabolic response of P. putida KT2442 producing high levels of polyhydroxyalkanoate under single- and multiple-nutrient-limited growth: highlights from a multi-level omics approach. | Microbial cell factories 20120101 |
Regulatory tasks of the phosphoenolpyruvate-phosphotransferase system of Pseudomonas putida in central carbon metabolism. | mBio 20120101 |
Aspects of astrocyte energy metabolism, amino acid neurotransmitter homoeostasis and metabolic compartmentation. | ASN neuro 20120101 |
Novel polysome messages and changes in translational activity appear after induction of adipogenesis in 3T3-L1 cells. | BMC molecular biology 20120101 |
An enrichment medium for increasing a very small number of vibrio parahaemolyticus cells to the detection limit of the loop-mediated isothermal amplification (LAMP) assay. | Japanese journal of infectious diseases 20120101 |
Hypoxia negatively regulates antimetastatic PEDF in melanoma cells by a hypoxia inducible factor-independent, autophagy dependent mechanism. | PloS one 20120101 |
Comparative proteomic analysis of early salt stress-responsive proteins in roots of SnRK2 transgenic rice. | Proteome science 20120101 |
Inhibition of SIRT1 impairs the accumulation and transcriptional activity of HIF-1α protein under hypoxic conditions. | PloS one 20120101 |
Gene expression in Atlantic salmon skin in response to infection with the parasitic copepod Lepeophtheirus salmonis, cortisol implant, and their combination. | BMC genomics 20120101 |
Metabonomic profiles delineate the effect of traditional Chinese medicine sini decoction on myocardial infarction in rats. | PloS one 20120101 |
Acid-base disorders in patients with chronic obstructive pulmonary disease: a pathophysiological review. | Journal of biomedicine & biotechnology 20120101 |
Glutathione homeostasis and functions: potential targets for medical interventions. | Journal of amino acids 20120101 |
Proteomic and bioinformatics analyses of mouse liver microsomes. | International journal of proteomics 20120101 |
Engineering a hyperthermophilic archaeon for temperature-dependent product formation. | mBio 20120101 |
Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D. | PloS one 20120101 |
Altered metabolic signature in pre-diabetic NOD mice. | PloS one 20120101 |
Physiology and pathology of calcium signaling in the brain. | Frontiers in pharmacology 20120101 |
Comparative analyses of homocitrate synthase genes of ascomycetous yeasts. | International journal of evolutionary biology 20120101 |
New insights in the amyloid-Beta interaction with mitochondria. | Journal of aging research 20120101 |
Identification of protein networks involved in the disease course of experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis. | PloS one 20120101 |
The redox imbalance and the reduction of contractile protein content in rat hearts administered with L-thyroxine and Doxorubicin. | Oxidative medicine and cellular longevity 20120101 |
Anticonvulsant drugs, brain glutamate dehydrogenase activity and oxygen consumption. | ISRN pharmacology 20120101 |
GABA metabolism and transport: effects on synaptic efficacy. | Neural plasticity 20120101 |
Does Branched-Chain Amino Acids Supplementation Modulate Skeletal Muscle Remodeling through Inflammation Modulation? Possible Mechanisms of Action. | Journal of nutrition and metabolism 20120101 |
Hypoxic-ischemic injury in the developing brain: the role of reactive oxygen species originating in mitochondria. | Neurology research international 20120101 |
Major Functional Transcriptome of an Inferred Center Regulator of an ER(-) Breast Cancer Model System. | Cancer informatics 20120101 |
Transcriptome profiling of the intoxication response of Tenebrio molitor larvae to Bacillus thuringiensis Cry3Aa protoxin. | PloS one 20120101 |
Mutational analysis of the cyanobacterial nitrogen regulator PipX. | PloS one 20120101 |
Salmonella enterica: a surprisingly well-adapted intracellular lifestyle. | Frontiers in microbiology 20120101 |
Effects of combined maternal administration with alpha-ketoglutarate (AKG) and β-hydroxy-β-methylbutyrate (HMB) on prenatal programming of skeletal properties in the offspring. | Nutrition & metabolism 20120101 |
The chimeric genome of Sphaerochaeta: nonspiral spirochetes that break with the prevalent dogma in spirochete biology. | mBio 20120101 |
DipA, a pore-forming protein in the outer membrane of Lyme disease spirochetes exhibits specificity for the permeation of dicarboxylates. | PloS one 20120101 |
Comparative genome analysis of central nitrogen metabolism and its control by GlnR in the class Bacilli. | BMC genomics 20120101 |
Implication of mitochondrial cytoprotection in human islet isolation and transplantation. | Biochemistry research international 20120101 |
AS601245, an Anti-Inflammatory JNK Inhibitor, and Clofibrate Have a Synergistic Effect in Inducing Cell Responses and in Affecting the Gene Expression Profile in CaCo-2 Colon Cancer Cells. | PPAR research 20120101 |
Assessment of periodontal health status in patients undergoing renal dialysis: A descriptive, cross-sectional study. | Journal of Indian Society of Periodontology 20120101 |
Degradation of 2,4-dichlorophenoxyacetic acid by a halotolerant strain of Penicillium chrysogenum: antibiotic production. | Environmental technology 20120101 |
The plant mitochondrial carrier family: functional and evolutionary aspects. | Frontiers in plant science 20120101 |
The mode of sucrose degradation in potato tubers determines the fate of assimilate utilization. | Frontiers in plant science 20120101 |
Transgenic Introduction of a Glycolate Oxidative Cycle into A. thaliana Chloroplasts Leads to Growth Improvement. | Frontiers in plant science 20120101 |
Recent Advances on the Posttranslational Modifications of EXTs and Their Roles in Plant Cell Walls. | Frontiers in plant science 20120101 |
Does a similar metabolic reprogramming occur in fe-deficient plant cells and animal tumor cells? | Frontiers in plant science 20120101 |
Ion channels and zinc: mechanisms of neurotoxicity and neurodegeneration. | Journal of toxicology 20120101 |
The succinate receptor as a novel therapeutic target for oxidative and metabolic stress-related conditions. | Frontiers in endocrinology 20120101 |
The Roles of VHL-Dependent Ubiquitination in Signaling and Cancer. | Frontiers in oncology 20120101 |
Expression of mitochondrial branched-chain aminotransferase and α-keto-acid dehydrogenase in rat brain: implications for neurotransmitter metabolism. | Frontiers in neuroanatomy 20120101 |
Glutathione supplementation attenuates lipopolysaccharide-induced mitochondrial dysfunction and apoptosis in a mouse model of acute lung injury. | Frontiers in physiology 20120101 |
Evolution and expression of tandem duplicated maize flavonol synthase genes. | Frontiers in plant science 20120101 |
Complete Genome of Ignavibacterium album, a Metabolically Versatile, Flagellated, Facultative Anaerobe from the Phylum Chlorobi. | Frontiers in microbiology 20120101 |
Investigating potential mechanisms of obesity by metabolomics. | Journal of biomedicine & biotechnology 20120101 |
Effects of aging and anatomic location on gene expression in human retina. | Frontiers in aging neuroscience 20120101 |
Identification of functional differences in metabolic networks using comparative genomics and constraint-based models. | PloS one 20120101 |
Tirapazamine-doxorubicin interaction referring to heart oxidative stress and Ca²⁺ balance protein levels. | Oxidative medicine and cellular longevity 20120101 |
Pancreatic function, type 2 diabetes, and metabolism in aging. | International journal of endocrinology 20120101 |
The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells. | International journal of cell biology 20120101 |
Phenotypic and transcriptomic response of auxotrophic Mycobacterium avium subsp. paratuberculosis leuD mutant under environmental stress. | PloS one 20120101 |
Arsenic toxicity: the effects on plant metabolism. | Frontiers in physiology 20120101 |
Metabolite adjustments in drought tolerant and sensitive soybean genotypes in response to water stress. | PloS one 20120101 |
Sex differences associated with primary biliary cirrhosis. | Clinical & developmental immunology 20120101 |
Intracellular pathogen Leishmania donovani activates hypoxia inducible factor-1 by dual mechanism for survival advantage within macrophage. | PloS one 20120101 |
Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects. | Oxidative medicine and cellular longevity 20120101 |
Kinetic Modeling of the Mitochondrial Energy Metabolism of Neuronal Cells: The Impact of Reduced α-Ketoglutarate Dehydrogenase Activities on ATP Production and Generation of Reactive Oxygen Species. | International journal of cell biology 20120101 |
Comparative proteomics of inner membrane fraction from carbapenem-resistant Acinetobacter baumannii with a reference strain. | PloS one 20120101 |
Characteristic features of kynurenine aminotransferase allosterically regulated by (alpha)-ketoglutarate in cooperation with kynurenine. | PloS one 20120101 |
Metabolomics approach for analyzing the effects of exercise in subjects with type 1 diabetes mellitus. | PloS one 20120101 |
Improved training tolerance by supplementation with α-Keto acids in untrained young adults: a randomized, double blind, placebo-controlled trial. | Journal of the International Society of Sports Nutrition 20120101 |
Distribution and prediction of catalytic domains in 2-oxoglutarate dependent dioxygenases. | BMC research notes 20120101 |
Phosphonate analogs of 2-oxoglutarate perturb metabolism and gene expression in illuminated Arabidopsis leaves. | Frontiers in plant science 20120101 |
Thiamine-responsive megaloblastic anemia syndrome: a novel mutation. | Genetic counseling (Geneva, Switzerland) 20120101 |
Regulation of the cyanobacterial CO2-concentrating mechanism involves internal sensing of NADP+ and α-ketogutarate levels by transcription factor CcmR. | PloS one 20120101 |
Bioconjugates of PAMAM dendrimers with trans-retinal, pyridoxal, and pyridoxal phosphate. | International journal of nanomedicine 20120101 |
Fe(II)-dependent, uridine-5'-monophosphate α-ketoglutarate dioxygenases in the synthesis of 5'-modified nucleosides. | Methods in enzymology 20120101 |
Enzymatic chlorination and bromination. | Methods in enzymology 20120101 |
Compromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibrium. | PloS one 20120101 |
Molecular mechanisms and metabolic engineering of glutamate overproduction in Corynebacterium glutamicum. | Sub-cellular biochemistry 20120101 |
Microbiologically produced carboxylic acids used as building blocks in organic synthesis. | Sub-cellular biochemistry 20120101 |
Mimivirus collagen is modified by bifunctional lysyl hydroxylase and glycosyltransferase enzyme. | The Journal of biological chemistry 20111223 |
The tricarboxylic acid cycle in cyanobacteria. | Science (New York, N.Y.) 20111216 |
Bezielle (BZL101)-induced oxidative stress damage followed by redistribution of metabolic fluxes in breast cancer cells: a combined proteomic and metabolomic study. | International journal of cancer 20111215 |
Actions of juglone on energy metabolism in the rat liver. | Toxicology and applied pharmacology 20111215 |
2-oxoglutarate enhances NtcA binding activity to promoter regions of the microcystin synthesis gene cluster. | FEBS letters 20111215 |
Comparative metabolic flux profiling of melanoma cell lines: beyond the Warburg effect. | The Journal of biological chemistry 20111209 |
Lipoic acid synthetase deficiency causes neonatal-onset epilepsy, defective mitochondrial energy metabolism, and glycine elevation. | American journal of human genetics 20111209 |
Thiamine pyrophosphokinase deficiency in encephalopathic children with defects in the pyruvate oxidation pathway. | American journal of human genetics 20111209 |
Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family. | The Journal of biological chemistry 20111202 |
Brain [U-13 C]glucose metabolism in mice with decreased α-ketoglutarate dehydrogenase complex activity. | Journal of neuroscience research 20111201 |
Astrocytic energy metabolism and glutamate formation--relevance for 13C-NMR spectroscopy and importance of cytosolic/mitochondrial trafficking. | Magnetic resonance imaging 20111201 |
Barley leaf transcriptome and metabolite analysis reveals new aspects of compatibility and Piriformospora indica-mediated systemic induced resistance to powdery mildew. | Molecular plant-microbe interactions : MPMI 20111201 |
Metabolite channeling and compartmentation in the human cell line AGE1.HN determined by 13C labeling experiments and 13C metabolic flux analysis. | Journal of bioscience and bioengineering 20111201 |
Mechanistic and structural studies of the N-hydroxylating flavoprotein monooxygenases. | Bioorganic chemistry 20111201 |
Effect of biosynthetic intermediates and citrate on the phenyllactic and hydroxyphenyllactic acids production by Lactobacillus plantarum CRL 778. | Journal of applied microbiology 20111201 |
Opaque7 encodes an acyl-activating enzyme-like protein that affects storage protein synthesis in maize endosperm. | Genetics 20111201 |
Isocitrate dehydrogenase mutations in gliomas: mechanisms, biomarkers and therapeutic target. | Current opinion in neurology 20111201 |
α-Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition. | Nature chemical biology 20111201 |
Microbial degradation of furanic compounds: biochemistry, genetics, and impact. | Applied microbiology and biotechnology 20111201 |
A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell death. | Cancer biology & therapy 20111201 |
[IDH1/2 mutations in gliomas]. | Brain and nerve = Shinkei kenkyu no shinpo 20111201 |
A genetic screening strategy identifies novel regulators of the proteostasis network. | PLoS genetics 20111201 |
An investigation into the cytotoxic effects of 13-acetoxysarcocrassolide from the soft coral Sarcophyton crassocaule on bladder cancer cells. | Marine drugs 20111201 |
Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia. | Nature 20111120 |
Mutations in the dimer interface of dihydrolipoamide dehydrogenase promote site-specific oxidative damages in yeast and human cells. | The Journal of biological chemistry 20111118 |
Simulating the physiology of athletes during endurance sports events: modelling human energy conversion and metabolism. | Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20111113 |
The cardiovascular risk of healthy individuals studied by NMR metabonomics of plasma samples. | Journal of proteome research 20111104 |
Proteomic dissection of the von Hippel-Lindau (VHL) interactome. | Journal of proteome research 20111104 |
[Effect of gamma-glutamyl kinase gene knock-out on metabolism in L-arginine-producing strain Corynebacterium crenatum 8-193]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20111104 |
The proteome of cytosolic lipid droplets isolated from differentiated Caco-2/TC7 enterocytes reveals cell-specific characteristics. | Biology of the cell 20111101 |
Label-free shotgun proteomics and metabolite analysis reveal a significant metabolic shift during citrus fruit development. | Journal of experimental botany 20111101 |
Differential interaction of dicarboxylates with human sodium-dicarboxylate cotransporter 3 and organic anion transporters 1 and 3. | American journal of physiology. Renal physiology 20111101 |
Ratiometric high-resolution imaging of JC-1 fluorescence reveals the subcellular heterogeneity of astrocytic mitochondria. | Pflugers Archiv : European journal of physiology 20111101 |
A lymphoblast model for IDH2 gain-of-function activity in d-2-hydroxyglutaric aciduria type II: novel avenues for biochemical and therapeutic studies. | Biochimica et biophysica acta 20111101 |
The Lys20 homocitrate synthase isoform exerts most of the flux control over the lysine synthesis pathway in Saccharomyces cerevisiae. | Molecular microbiology 20111101 |
Tyrosine aminotransferase contributes to benzylisoquinoline alkaloid biosynthesis in opium poppy. | Plant physiology 20111101 |
Overproduction and secretion of α-ketoglutaric acid by microorganisms. | Applied microbiology and biotechnology 20111101 |
Whole-exome sequencing detects somatic mutations of IDH1 in metaphyseal chondromatosis with D-2-hydroxyglutaric aciduria (MC-HGA). | American journal of medical genetics. Part A 20111101 |
Novel insights into FH-associated disease are KEAPing the lid on oncogenic HIF signalling. | Oncotarget 20111101 |
Identification of biochemical network modules based on shortest retroactive distances. | PLoS computational biology 20111101 |
Serum alanine aminotransferase concentration as a predictive factor for the development or regression of fatty liver. | Journal of clinical biochemistry and nutrition 20111101 |
Evaluating the reliability of analytical results using a probability criterion: a Bayesian perspective. | Analytica chimica acta 20111031 |
Structural basis for leucine-induced allosteric activation of glutamate dehydrogenase. | The Journal of biological chemistry 20111028 |
Elevated CO(2) levels cause mitochondrial dysfunction and impair cell proliferation. | The Journal of biological chemistry 20111028 |
Cell-free synthesis, reconstitution, and characterization of a mitochondrial dicarboxylate-tricarboxylate carrier of Plasmodium falciparum. | Biochemical and biophysical research communications 20111028 |
¹³C-metabolic enrichment of glutamate in glutamate dehydrogenase mutants of Saccharomyces cerevisiae. | Microbiological research 20111020 |
Renal cyst formation in Fh1-deficient mice is independent of the Hif/Phd pathway: roles for fumarate in KEAP1 succination and Nrf2 signaling. | Cancer cell 20111018 |
Complete genome sequence of Ferroglobus placidus AEDII12DO. | Standards in genomic sciences 20111015 |
Draft genome sequence of Caminibacter mediatlanticus strain TB-2, an epsilonproteobacterium isolated from a deep-sea hydrothermal vent. | Standards in genomic sciences 20111015 |
Using substrate analogues to probe the kinetic mechanism and active site of Escherichia coli MenD. | Biochemistry 20111011 |
Tricarboxylic acid cycle activity measured by 13C magnetic resonance spectroscopy in rats subjected to the kaolin model of obstructed hydrocephalus. | Neurochemical research 20111001 |
IDH1 and IDH2 mutations in pediatric acute leukemia. | Leukemia 20111001 |
Functional gene expression profile underlying methotrexate-induced senescence in human colon cancer cells. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20111001 |
A simple method for measuring intracellular activities of glutamine synthetase and glutaminase in glial cells. | American journal of physiology. Cell physiology 20111001 |
Regulation of glutamate metabolism by hydrocortisone and branched chain keto acids in cultured rat retinal Müller cells (TR-MUL). | Neurochemistry international 20111001 |
Hepatic response to aluminum toxicity: dyslipidemia and liver diseases. | Experimental cell research 20111001 |
Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction. | Archives of biochemistry and biophysics 20111001 |
Characterization of Bacillus thuringiensis L-isoleucine dioxygenase for production of useful amino acids. | Applied and environmental microbiology 20111001 |
L-Asparaginase and inhibitors of glutamine synthetase disclose glutamine addiction of β-catenin-mutated human hepatocellular carcinoma cells. | Current cancer drug targets 20111001 |
A mutation threshold distinguishes the antitumorigenic effects of the mitochondrial gene MTND1, an oncojanus function. | Cancer research 20111001 |
Antisense suppression of the small chloroplast protein CP12 in tobacco alters carbon partitioning and severely restricts growth. | Plant physiology 20111001 |
Metabolism of glioma and IDH1/IDH2 mutations. | Revue neurologique 20111001 |
Fumarate reductase activity maintains an energized membrane in anaerobic Mycobacterium tuberculosis. | PLoS pathogens 20111001 |
Enzymatic synthesis of L-tert-leucine with branched chain aminotransferase. | Journal of microbiology and biotechnology 20111001 |
Fuel-Stimulated Insulin Secretion Depends upon Mitochondria Activation and the Integration of Mitochondrial and Cytosolic Substrate Cycles. | Diabetes & metabolism journal 20111001 |
Quantitative mass spectrometry reveals dynamics of factor-inhibiting hypoxia-inducible factor-catalyzed hydroxylation. | The Journal of biological chemistry 20110930 |
Characterization and application of the Fe(II) and α-ketoglutarate dependent hydroxylase FrbJ. | Chemical communications (Cambridge, England) 20110928 |
The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH. | Archives of biochemistry and biophysics 20110915 |
Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells. | Cell metabolism 20110907 |
Assignment of function to histidines 260 and 298 by engineering the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase complex; substitutions that lead to acceptance of substrates lacking the 5-carboxyl group. | Biochemistry 20110906 |
A role for prolyl 3-hydroxylase 2 in post-translational modification of fibril-forming collagens. | The Journal of biological chemistry 20110902 |
Stimulatory effects of calcium on respiration and NAD(P)H synthesis in intact rat heart mitochondria utilizing physiological substrates cannot explain respiratory control in vivo. | The Journal of biological chemistry 20110902 |
The human GLUD2 glutamate dehydrogenase and its regulation in health and disease. | Neurochemistry international 20110901 |
Endogenous 2-oxoglutarate levels impact potencies of competitive HIF prolyl hydroxylase inhibitors. | Pharmacological research 20110901 |
Carbohydrate metabolite pathways and antibiotic production variations of a novel Streptomyces sp. M3004 depending on the concentrations of carbon sources. | Applied biochemistry and biotechnology 20110901 |
Titanium surface topography affects collagen biosynthesis of adherent cells. | Bone 20110901 |
Metabolic surgery profoundly influences gut microbial-host metabolic cross-talk. | Gut 20110901 |
Enzymatic characterization of isocitrate dehydrogenase from an emerging zoonotic pathogen Streptococcus suis. | Biochimie 20110901 |
Quantitative shotgun proteomics using a uniform ¹⁵N-labeled standard to monitor proteome dynamics in time course experiments reveals new insights into the heat stress response of Chlamydomonas reinhardtii. | Molecular & cellular proteomics : MCP 20110901 |
Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways. | Neurochemistry international 20110901 |
Bioenergetic dysfunction in Huntington's disease human cybrids. | Experimental neurology 20110901 |
Glutamine and α-ketoglutarate as glutamate sources for glutathione synthesis in human erythrocytes. | The FEBS journal 20110901 |
Metabolic flux analysis of CHO cells at growth and non-growth phases using isotopic tracers and mass spectrometry. | Metabolic engineering 20110901 |
Mutations to metabolic enzymes in cancer herald a need to unify genetics and biochemistry. | Cell cycle (Georgetown, Tex.) 20110901 |
A switching mechanism in doxorubicin bioactivation can be exploited to control doxorubicin toxicity. | PLoS computational biology 20110901 |
Virtual mutagenesis of isocitrate dehydrogenase 1 involved in glioblastoma multiforme. | Chinese medical journal 20110901 |
Overexpression of the Trichoderma brevicompactum tri5 gene: effect on the expression of the trichodermin biosynthetic genes and on tomato seedlings. | Toxins 20110901 |
Functional plasticity and allosteric regulation of α-ketoglutarate decarboxylase in central mycobacterial metabolism. | Chemistry & biology 20110826 |
Kinetic and chemical mechanisms of homocitrate synthase from Thermus thermophilus. | The Journal of biological chemistry 20110819 |
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. | Nature 20110818 |
Variation in antibiotic-induced microbial recolonization impacts on the host metabolic phenotypes of rats. | Journal of proteome research 20110805 |
Radiotherapy and temozolomide for newly diagnosed glioblastoma and anaplastic astrocytoma: validation of Radiation Therapy Oncology Group-Recursive Partitioning Analysis in the IMRT and temozolomide era. | Journal of neuro-oncology 20110801 |
Isocitrate dehydrogenase mutations: a challenge to traditional views on the genesis and malignant progression of gliomas. | Glia 20110801 |
Effects of α-ketoglutarate on energy status in the intestinal mucosa of weaned piglets chronically challenged with lipopolysaccharide. | The British journal of nutrition 20110801 |
The organellar genome and metabolic potential of the hydrogen-producing mitochondrion of Nyctotherus ovalis. | Molecular biology and evolution 20110801 |
Inhibition of 2-oxoglutarate dependent oxygenases. | Chemical Society reviews 20110801 |
Computational analysis of storage synthesis in developing Brassica napus L. (oilseed rape) embryos: flux variability analysis in relation to ¹³C metabolic flux analysis. | The Plant journal : for cell and molecular biology 20110801 |
Arginine synthesis from enteral glutamine in healthy adults in the fed state. | American journal of physiology. Endocrinology and metabolism 20110801 |
Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles. | Toxicological sciences : an official journal of the Society of Toxicology 20110801 |
Exercise training induces similar elevations in the activity of oxoglutarate dehydrogenase and peak oxygen uptake in the human quadriceps muscle. | Pflugers Archiv : European journal of physiology 20110801 |
The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase. | Rejuvenation research 20110801 |
Energetic metabolism of axenic promastigotes of Leishmania (Viannia) braziliensis. | Experimental parasitology 20110801 |
Lipoamide dehydrogenase is essential for both bloodstream and procyclic Trypanosoma brucei. | Molecular microbiology 20110801 |
Pd-Fe nanoparticles stabilized by chitosan derivatives for perchloroethene dechlorination. | Environment international 20110801 |
Acetyl-CoA metabolism in amprolium-evoked thiamine pyrophosphate deficits in cholinergic SN56 neuroblastoma cells. | Neurochemistry international 20110801 |
Heme biosynthesis and its regulation: towards understanding and improvement of heme biosynthesis in filamentous fungi. | Applied microbiology and biotechnology 20110801 |
Renewable energy from Cyanobacteria: energy production optimization by metabolic pathway engineering. | Applied microbiology and biotechnology 20110801 |
The control of mitochondrial succinate-dependent H2O2 production. | Journal of bioenergetics and biomembranes 20110801 |
Simulation of dissolved CO(2) gradients in a scale-down system: a metabolic and transcriptional study of recombinant Escherichia coli. | Biotechnology journal 20110801 |
Succinate receptors in the kidney. | Journal of the American Society of Nephrology : JASN 20110801 |
Crystallization and preliminary crystallographic analysis of a PHD domain of human JARID1B. | Acta crystallographica. Section F, Structural biology and crystallization communications 20110801 |
Modes of action of microbially-produced phytotoxins. | Toxins 20110801 |
Melatonin and succinate reduce rat liver mitochondrial dysfunction in diabetes. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110801 |
Can metabolic plasticity be a cause for cancer? Warburg-Waddington legacy revisited. | Clinical epigenetics 20110801 |
Identification of ChIP-seq mapped targets of HP1β due to bombesin/GRP receptor activation. | Clinical epigenetics 20110801 |
Toxicity of alpha-ketoglutarate following 14-days repeated oral administration in Wistar rats. | Cellular and molecular biology (Noisy-le-Grand, France) 20110727 |
Multiple targets of nitric oxide in the tricarboxylic acid cycle of Salmonella enterica serovar typhimurium. | Cell host & microbe 20110721 |
The redox basis of epigenetic modifications: from mechanisms to functional consequences. | Antioxidants & redox signaling 20110715 |
GSH monoethyl ester rescues mitochondrial defects in cystic fibrosis models. | Human molecular genetics 20110715 |
Waves of gene regulation suppress and then restore oxidative phosphorylation in cancer cells. | The international journal of biochemistry & cell biology 20110701 |
Combining proteomics of root and shoot mitochondria and transcript analysis to define constitutive and variable components in plant mitochondria. | Phytochemistry 20110701 |
Metabolic fate of a high concentration of glutamine and glutamate in rat brain slices: a ¹³C NMR study. | Neurochemistry international 20110701 |
Thiamine responsive megaloblastic anemia in three Indian children. | Indian journal of pediatrics 20110701 |
Acute arginine supplementation fails to improve muscle endurance or affect blood pressure responses to resistance training. | Journal of strength and conditioning research 20110701 |
Proteomic analysis of protective effects of polysaccharides from Salvia miltiorrhiza against immunological liver injury in mice. | Phytotherapy research : PTR 20110701 |
Epithelial cell specificity and apotope recognition by serum autoantibodies in primary biliary cirrhosis. | Hepatology (Baltimore, Md.) 20110701 |
Characterization of two critical residues in the effector-binding domain of NtcA in the cyanobacterium Anabaena sp. strain PCC 7120. | Current microbiology 20110701 |
Investigation of phosphorylation status of OdhI protein during penicillin- and Tween 40-triggered glutamate overproduction by Corynebacterium glutamicum. | Applied microbiology and biotechnology 20110701 |
Does ear C sink strength contribute to overcoming photosynthetic acclimation of wheat plants exposed to elevated CO2? | Journal of experimental botany 20110701 |
Alterations in urinary metabolites due to unilateral ureteral obstruction in a rodent model. | Molecular bioSystems 20110701 |
Gene profiling and characterization of arginine kinase-1 (MrAK-1) from freshwater giant prawn (Macrobrachium rosenbergii). | Fish & shellfish immunology 20110701 |
Maternal nutrient restriction during late gestation and early postnatal growth in sheep differentially reset the control of energy metabolism in the gastric mucosa. | Endocrinology 20110701 |
Viral effects on metabolism: changes in glucose and glutamine utilization during human cytomegalovirus infection. | Trends in microbiology 20110701 |
Pharmacological effect of carvacrol on D: -galactosamine-induced mitochondrial enzymes and DNA damage by single-cell gel electrophoresis. | Journal of natural medicines 20110701 |
Genomic analysis of Acidianus hospitalis W1 a host for studying crenarchaeal virus and plasmid life cycles. | Extremophiles : life under extreme conditions 20110701 |
Hypothesis: environmental regulation of 5-hydroxymethylcytosine by oxidative stress. | Epigenetics 20110701 |
Glioma-derived mutations in isocitrate dehydrogenase 2 beneficial to traditional chemotherapy. | Biochemical and biophysical research communications 20110701 |
Identification of metabolic network models from incomplete high-throughput datasets. | Bioinformatics (Oxford, England) 20110701 |
Detection of tumor glutamate metabolism in vivo using (13)C magnetic resonance spectroscopy and hyperpolarized [1-(13)C]glutamate. | Magnetic resonance in medicine 20110701 |
Suppression of glutamate synthase genes significantly affects carbon and nitrogen metabolism in rice (Oryza sativa L.). | Science China. Life sciences 20110701 |
Divergent effects of human cytomegalovirus and herpes simplex virus-1 on cellular metabolism. | PLoS pathogens 20110701 |
Protective effect of aqueous garlic extract against lead-induced hepatic injury in rats. | Indian journal of experimental biology 20110701 |
In silico evidence for gluconeogenesis from fatty acids in humans. | PLoS computational biology 20110701 |
¹³C metabolic flux analysis identifies an unusual route for pyruvate dissimilation in mycobacteria which requires isocitrate lyase and carbon dioxide fixation. | PLoS pathogens 20110701 |
Flux balance analysis for ethylene formation in genetically engineered Saccharomyces cerevisiae. | IET systems biology 20110701 |
Lysine α-ketoglutarate reductase, but not saccharopine dehydrogenase, is subject to substrate inhibition in pig liver. | Nutrition research (New York, N.Y.) 20110701 |
Complete genome sequence of Rhodospirillum rubrum type strain (S1). | Standards in genomic sciences 20110701 |
The disruption of L-carnitine metabolism by aluminum toxicity and oxidative stress promotes dyslipidemia in human astrocytic and hepatic cells. | Toxicology letters 20110624 |
A zinc finger protein, TbZC3H20, stabilizes two developmentally regulated mRNAs in trypanosomes. | The Journal of biological chemistry 20110610 |
X-ray absorption spectroscopy structural investigation of early intermediates in the mechanism of DNA repair by human ABH2. | Biochemistry 20110607 |
2-difluoromethylene-4-methylenepentanoic acid, a paradoxical probe able to mimic the signaling role of 2-oxoglutaric acid in cyanobacteria. | Organic letters 20110603 |
Vernonia cinerea Less. inhibits tumor cell invasion and pulmonary metastasis in C57BL/6 mice. | Integrative cancer therapies 20110601 |
The correlations between TCA-glyoxalate metabolite and antibiotic production of Streptomyces sp. M4018 grown in glycerol, glucose, and starch mediums. | Applied biochemistry and biotechnology 20110601 |
Urinary 2-hydroxy-5-oxoproline, the lactam form of α-ketoglutaramate, is markedly increased in urea cycle disorders. | Analytical and bioanalytical chemistry 20110601 |
Transient excretion of succinate from Trichoderma atroviride submerged mycelia reveals the complex movements and metabolism of carboxylates. | Antonie van Leeuwenhoek 20110601 |
Pharmacological characterization of 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid (JNJ-42041935), a potent and selective hypoxia-inducible factor prolyl hydroxylase inhibitor. | Molecular pharmacology 20110601 |
Synthesis of neurotransmitter GABA via the neuronal tricarboxylic acid cycle is elevated in rats with liver cirrhosis consistent with a high GABAergic tone in chronic hepatic encephalopathy. | Journal of neurochemistry 20110601 |
(R,S)-dichlorprop herbicide in agricultural soil induces proliferation and expression of multiple dioxygenase-encoding genes in the indigenous microbial community. | Environmental microbiology 20110601 |
Actinotrichia collagens and their role in fin formation. | Developmental biology 20110601 |
Structural basis of fumarate hydratase deficiency. | Journal of inherited metabolic disease 20110601 |
Chronic alcoholism in rats induces a compensatory response, preserving brain thiamine diphosphate, but the brain 2-oxo acid dehydrogenases are inactivated despite unchanged coenzyme levels. | Journal of neurochemistry 20110601 |
A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation. | PLoS genetics 20110601 |
H NMR spectroscopy-based metabolomic assessment of uremic toxicity, with toxicological outcomes, in male rats following an acute, mid-life insult from ochratoxin a. | Toxins 20110601 |
Non-alcoholic fatty liver disease and correlation of serum alanin aminotransferase level with histopathologic findings. | Hepatitis monthly 20110601 |
[Study on influence of glucoside Tripterygium total tablets on metabolism in rats by NMR metabonomic technique]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110601 |
Expression and functional analysis of glutamate synthase small subunit-like proteins from archaeon Pyrococcus horikoshii. | Microbiological research 20110520 |
Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex. | The Journal of biological chemistry 20110520 |
Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase. | Biochemical and biophysical research communications 20110520 |
Vitamin C is dispensable for oxygen sensing in vivo. | Blood 20110519 |
Two antioxidants are better than one. | Blood 20110519 |
Observation of two families of folding pathways of BBL. | Biophysical journal 20110518 |
Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells. | Molecular and cellular endocrinology 20110516 |
Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia. | Journal of proteome research 20110506 |
Metabolic reprogramming by HIF-1 promotes the survival of bone marrow-derived angiogenic cells in ischemic tissue. | Blood 20110505 |
Substrate specificity of 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum: toward a bio-based production of adipic acid. | Biochemistry 20110503 |
Inhibition of histone demethylases by 4-carboxy-2,2'-bipyridyl compounds. | ChemMedChem 20110502 |
Rosette-forming glioneuronal tumor: a pineal region case with IDH1 and IDH2 mutation analyses and literature review of 43 cases. | Journal of neuro-oncology 20110501 |
Cervical softening during pregnancy: regulated changes in collagen cross-linking and composition of matricellular proteins in the mouse. | Biology of reproduction 20110501 |
Could thiamine pyrophosphate be a regulator of the nitric oxide synthesis in the endothelial cell of diabetic patients? | Medical hypotheses 20110501 |
The tricarboxylic acid cycle in L₃ Teladorsagia circumcincta: metabolism of acetyl CoA to succinyl CoA. | Experimental parasitology 20110501 |
Identification of urinary biomarkers from X-irradiated mice using NMR spectroscopy. | Radiation research 20110501 |
Urine metabolomic analysis identifies potential biomarkers and pathogenic pathways in kidney cancer. | Omics : a journal of integrative biology 20110501 |
Three 2-oxoglutarate-dependent dioxygenase activities of Equisetum arvense L. forming flavone and flavonol from (2S)-naringenin. | Phytochemistry 20110501 |
Deamination role of inducible glutamate dehydrogenase isoenzyme 7 in Brassica napus leaf protoplasts. | Phytochemistry 20110501 |
Multienzyme-modified biosensing surface for the electrochemical analysis of aspartate transaminase and alanine transaminase in human plasma. | Analytical and bioanalytical chemistry 20110501 |
Uncoupled O2-activation in the human HIF-asparaginyl hydroxylase, FIH, does not produce reactive oxygen species. | Journal of inorganic biochemistry 20110501 |
The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. | EMBO reports 20110501 |
Effect of acute hypoglycemia on human cerebral glucose metabolism measured by ¹³C magnetic resonance spectroscopy. | Diabetes 20110501 |
Genetic factors in isolated and syndromic esophageal atresia. | Journal of pediatric gastroenterology and nutrition 20110501 |
Magnetic resonance spectroscopy studies of human metabolism. | Diabetes 20110501 |
Os-GIGANTEA confers robust diurnal rhythms on the global transcriptome of rice in the field. | The Plant cell 20110501 |
Genome of Herbaspirillum seropedicae strain SmR1, a specialized diazotrophic endophyte of tropical grasses. | PLoS genetics 20110501 |
Development of nano alpha-ketoglutarate nebulization formulation and its pharmacokinetic and safety evaluation in healthy human volunteers for cyanide poisoning. | Environmental toxicology and pharmacology 20110501 |
Mutations in PPIB (cyclophilin B) delay type I procollagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes. | Human molecular genetics 20110415 |
Development of amperometric α-ketoglutarate biosensor based on ruthenium-rhodium modified carbon fiber enzyme microelectrode. | Biosensors & bioelectronics 20110415 |
Differential sensitivity of hypoxia inducible factor hydroxylation sites to hypoxia and hydroxylase inhibitors. | The Journal of biological chemistry 20110415 |
The last step of the biosynthesis of the cyanotoxins cylindrospermopsin and 7-epi-cylindrospermopsin is catalysed by CyrI, a 2-Oxoglutarate-dependent iron oxygenase. | Chembiochem : a European journal of chemical biology 20110411 |
Biochemical diagnosis of mitochondrial disorders. | Journal of inherited metabolic disease 20110401 |
Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production. | Amino acids 20110401 |
Papillary thyroid carcinoma shows elevated levels of 2-hydroxyglutarate. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110401 |
A gold nanoparticle-mediated enzyme bioreactor for inhibitor screening by capillary electrophoresis. | Analytical biochemistry 20110401 |
¹H-NMR-based metabonomic analysis of metabolic profiling in diabetic nephropathy rats induced by streptozotocin. | American journal of physiology. Renal physiology 20110401 |
Redox signaling in cardiac myocytes. | Free radical biology & medicine 20110401 |
The sodium-dependent di- and tricarboxylate transporter, NaCT, is not responsible for the uptake of D-, L-2-hydroxyglutarate and 3-hydroxyglutarate into neurons. | Journal of inherited metabolic disease 20110401 |
Isocitrate dehydrogenase mutations may be a protective mechanism in glioma patients. | Medical hypotheses 20110401 |
The influence of diabetes on glutamate metabolism in retinas. | Journal of neurochemistry 20110401 |
Plant D-2-hydroxyglutarate dehydrogenase participates in the catabolism of lysine especially during senescence. | The Journal of biological chemistry 20110401 |
Lactate influx through the endothelial cell monocarboxylate transporter MCT1 supports an NF-κB/IL-8 pathway that drives tumor angiogenesis. | Cancer research 20110401 |
Cloning, expression and characterization of a new aspartate aminotransferase from Bacillus subtilis B3. | The FEBS journal 20110401 |
Metabolic characterization of Palatinate German white wines according to sensory attributes, varieties, and vintages using NMR spectroscopy and multivariate data analyses. | Journal of biomolecular NMR 20110401 |
Role of aminotransferases in glutamate metabolism of human erythrocytes. | Journal of biomolecular NMR 20110401 |
A sister group contrast using untargeted global metabolomic analysis delineates the biochemical regulation underlying desiccation tolerance in Sporobolus stapfianus. | The Plant cell 20110401 |
Molecular determinants and genetic modifiers of aggregation and toxicity for the ALS disease protein FUS/TLS. | PLoS biology 20110401 |
The neuroprotective effect of 2-oxoglutarate in the experimental ischemia of hippocampus. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110401 |
Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis. | British journal of cancer 20110329 |
Lysyl hydroxylase 3 glucosylates galactosylhydroxylysine residues in type I collagen in osteoblast culture. | The Journal of biological chemistry 20110318 |
Regulation of erythropoietin production. | The Journal of physiology 20110315 |
Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4. | The Biochemical journal 20110315 |
Protein-protein interactions in assembly of lipoic acid on the 2-oxoacid dehydrogenases of aerobic metabolism. | The Journal of biological chemistry 20110311 |
Characterization of LipL as a non-heme, Fe(II)-dependent α-ketoglutarate:UMP dioxygenase that generates uridine-5'-aldehyde during A-90289 biosynthesis. | The Journal of biological chemistry 20110311 |
Biochemical and structural characterization of WlbA from Bordetella pertussis and Chromobacterium violaceum: enzymes required for the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid. | Biochemistry 20110308 |
The 2-oxoglutarate-dependent oxygenase JMJD6 catalyses oxidation of lysine residues to give 5S-hydroxylysine residues. | Chembiochem : a European journal of chemical biology 20110307 |
Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor. | The Journal of biological chemistry 20110304 |
Artefacts in cell culture: α-Ketoglutarate can scavenge hydrogen peroxide generated by ascorbate and epigallocatechin gallate in cell culture media. | Biochemical and biophysical research communications 20110304 |
Dioxygenases, key enzymes to determine the aglycon structures of fusicoccin and brassicicene, diterpene compounds produced by fungi. | Journal of the American Chemical Society 20110302 |
Overexpression of alpha-ketoglutarate dehydrogenase in Yarrowia lipolytica and its effect on production of organic acids. | Applied microbiology and biotechnology 20110301 |
Application of a high-throughput fluorescent acetyltransferase assay to identify inhibitors of homocitrate synthase. | Analytical biochemistry 20110301 |
Nitrate regulates floral induction in Arabidopsis, acting independently of light, gibberellin and autonomous pathways. | Planta 20110301 |
Abnormalities in the tricarboxylic acid (TCA) cycle in the brains of schizophrenia patients. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20110301 |
Functional and structural role of amino acid residues in the matrix alpha-helices, termini and cytosolic loops of the bovine mitochondrial oxoglutarate carrier. | Biochimica et biophysica acta 20110301 |
Effect of alpha-ketoglutarate on neurobehavioral, neurochemical and oxidative changes caused by sub-chronic cyanide poisoning in rats. | Neurochemical research 20110301 |
The rate of nitrite reduction in leaves as indicated by O₂ and CO₂ exchange during photosynthesis. | Journal of experimental botany 20110301 |
Thiamine-responsive megaloblastic anemia syndrome with atrial standstill: a case report. | Journal of pediatric hematology/oncology 20110301 |
Inborn and acquired metabolic defects in cancer. | Journal of molecular medicine (Berlin, Germany) 20110301 |
[Facial dysmorphism associated with ketoglutaric acid]. | Anales de pediatria (Barcelona, Spain : 2003) 20110301 |
Resolving the TCA cycle and pentose-phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis. | Biotechnology journal 20110301 |
Effects of polynitrogen compounds on the activity of recombinant human HIF-1α prolyl hydroxylase 3 in E. coli. | Journal of inorganic biochemistry 20110301 |
Does early treatment prevent deafness in thiamine-responsive megaloblastic anaemia syndrome? | Journal of clinical research in pediatric endocrinology 20110301 |
Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells. | PLoS computational biology 20110301 |
[Metabolic pathways of OGCP and the influence of parkin protein on the metabolism of OGCP]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110301 |
Studies on substrate specificity of Jmjd2a-c histone demethylases. | Biochemical and biophysical research communications 20110225 |
Ataxia telangiectasia mutated influences cytochrome c oxidase activity. | Biochemical and biophysical research communications 20110225 |
Structural basis for human PHF2 Jumonji domain interaction with metal ions. | Journal of molecular biology 20110211 |
Systems responses of rats to aflatoxin B1 exposure revealed with metabonomic changes in multiple biological matrices. | Journal of proteome research 20110204 |
Hesperidin attenuates mitochondrial dysfunction during benzo(a)pyrene-induced lung carcinogenesis in mice. | Fundamental & clinical pharmacology 20110201 |
Vibrio communis sp. nov., isolated from the marine animals Mussismilia hispida, Phyllogorgia dilatata, Palythoa caribaeorum, Palythoa variabilis and Litopenaeus vannamei. | International journal of systematic and evolutionary microbiology 20110201 |
Prolonged cold storage using a new histidine-tryptophan-ketoglutarate-based preservation solution in isogeneic cardiac mouse grafts. | European heart journal 20110201 |
Clinical, genetic and magnetic resonance findings in an Italian patient affected by L-2-hydroxyglutaric aciduria. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20110201 |
Immunoreactive Coxiella burnetii Nine Mile proteins separated by 2D electrophoresis and identified by tandem mass spectrometry. | Microbiology (Reading, England) 20110201 |
Effects of CaCl2 on viscosity of culture broth, and on activities of enzymes around the 2-oxoglutarate branch, in Bacillus subtilis CGMCC 2108 producing poly-(γ-glutamic acid). | Bioresource technology 20110201 |
Autoantibodies to GW bodies and other autoantigens in primary biliary cirrhosis. | Clinical and experimental immunology 20110201 |
Regulation of muscular glutamate metabolism by high-protein diet in broiler chicks. | Animal science journal = Nihon chikusan Gakkaiho 20110201 |
Respiration and nitrogen assimilation: targeting mitochondria-associated metabolism as a means to enhance nitrogen use efficiency. | Journal of experimental botany 20110201 |
Regulation of nitrate assimilation in cyanobacteria. | Journal of experimental botany 20110201 |
Structure of GlnK1, a signalling protein from Archaeoglobus fulgidus. | Acta crystallographica. Section F, Structural biology and crystallization communications 20110201 |
Antisense inhibition of the iron-sulphur subunit of succinate dehydrogenase enhances photosynthesis and growth in tomato via an organic acid-mediated effect on stomatal aperture. | The Plant cell 20110201 |
Alpha-ketoglutarate stabilizes redox homeostasis and improves arterial elasticity in aged mice. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201 |
Prevention of cadmium bioaccumulation by herbal adaptogens. | Indian journal of pharmacology 20110201 |
Specific inhibition of the aspartate aminotransferase of Plasmodium falciparum. | Journal of molecular biology 20110128 |
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. | Cancer cell 20110118 |
Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates. | Organic & biomolecular chemistry 20110107 |
Global metabolic phenotyping in an experimental laparotomy model of surgical trauma. | Journal of proteome research 20110107 |
Robust control of nitrogen assimilation by a bifunctional enzyme in E. coli. | Molecular cell 20110107 |
Metabonomic investigation of single and multiple strain Trypanosoma brucei brucei infections. | The American journal of tropical medicine and hygiene 20110105 |
Protective effects of chinese traditional medicine buyang huanwu decoction on myocardial injury. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
An mRNA blueprint for C4 photosynthesis derived from comparative transcriptomics of closely related C3 and C4 species. | Plant physiology 20110101 |
Glutamate synthase, but not GABA shunt enzymes, contributes to nitrogen metabolism of the sheep abomasal nematode parasites Haemonchus contortus and Teladorsagia circumcincta. | Experimental parasitology 20110101 |
Identification of up-regulated genes of Bacillus amyloliquefaciens B55 during the early stage of direct surface contact with rice R109 root. | Current microbiology 20110101 |
Gene expression patterns in bone following mechanical loading. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110101 |
Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases. | Trends in biochemical sciences 20110101 |
Characterisation of the Drosophila procollagen lysyl hydroxylase, dPlod. | Gene expression patterns : GEP 20110101 |
Therapeutic modulation of cerebral L-lysine metabolism in a mouse model for glutaric aciduria type I. | Brain : a journal of neurology 20110101 |
Nitrogen metabolism responses to water deficit act through both abscisic acid (ABA)-dependent and independent pathways in Medicago truncatula during post-germination. | Journal of experimental botany 20110101 |
Dimerization of human lysyl hydroxylase 3 (LH3) is mediated by the amino acids 541-547. | Matrix biology : journal of the International Society for Matrix Biology 20110101 |
Prooxidant activity of fisetin: effects on energy metabolism in the rat liver. | Journal of biochemical and molecular toxicology 20110101 |
Brain glutamine synthesis requires neuronal aspartate: a commentary. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20110101 |
Post-translational modifications in secreted peptide hormones in plants. | Plant & cell physiology 20110101 |
Differential toxicological effects induced by mercury in gills from three pedigrees of Manila clam Ruditapes philippinarum by NMR-based metabolomics. | Ecotoxicology (London, England) 20110101 |
Paintomics: a web based tool for the joint visualization of transcriptomics and metabolomics data. | Bioinformatics (Oxford, England) 20110101 |
α-Ketoglutarate dehydrogenase: a mitochondrial redox sensor. | Free radical research 20110101 |
HILIC-UPLC-MS for exploratory urinary metabolic profiling in toxicological studies. | Analytical chemistry 20110101 |
Histone deacetylase inhibitors: the epigenetic therapeutics that repress hypoxia-inducible factors. | Journal of biomedicine & biotechnology 20110101 |
The chloroplastic 2-oxoglutarate/malate transporter has dual function as the malate valve and in carbon/nitrogen metabolism. | The Plant journal : for cell and molecular biology 20110101 |
[Galactosemia associated with Rogers syndrome in a 10-month-old infant]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20110101 |
Alpha-Ketoglutarate and intestinal function. | Frontiers in bioscience (Landmark edition) 20110101 |
Metabolic pathway engineering based on metabolomics confers acetic and formic acid tolerance to a recombinant xylose-fermenting strain of Saccharomyces cerevisiae. | Microbial cell factories 20110101 |
SPABBATS: A pathway-discovery method based on Boolean satisfiability that facilitates the characterization of suppressor mutants. | BMC systems biology 20110101 |
Role of PII proteins in nitrogen fixation control of Herbaspirillum seropedicae strain SmR1. | BMC microbiology 20110101 |
Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets? | International journal of biological sciences 20110101 |
Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection. | Parkinson's disease 20110101 |
Malate plays a crucial role in starch metabolism, ripening, and soluble solid content of tomato fruit and affects postharvest softening. | The Plant cell 20110101 |
De novo designed proteins from a library of artificial sequences function in Escherichia coli and enable cell growth. | PloS one 20110101 |
Method development and validation for the analysis of a new anti-cancer infusion solution via HPLC. | Journal of separation science 20110101 |
Cardiogenol C can induce Mouse Hair Bulge Progenitor Cells to Transdifferentiate into Cardiomyocyte-like Cells. | Proteome science 20110101 |
Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease. | Molecular neurodegeneration 20110101 |
Human AlkB homologue 5 is a nuclear 2-oxoglutarate dependent oxygenase and a direct target of hypoxia-inducible factor 1α (HIF-1α). | PloS one 20110101 |
Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases. | Journal of biomedicine & biotechnology 20110101 |
Flux balance analysis of ammonia assimilation network in E. coli predicts preferred regulation point. | PloS one 20110101 |
Modulation of the major paths of carbon in photorespiratory mutants of synechocystis. | PloS one 20110101 |
A day in the life of microcystis aeruginosa strain PCC 7806 as revealed by a transcriptomic analysis. | PloS one 20110101 |
Essential metabolites of Mycobacterium tuberculosis and their mimics. | mBio 20110101 |
The prolyl hydroxylase enzymes are positively associated with hypoxia-inducible factor-1α and vascular endothelial growth factor in human breast cancer and alter in response to primary systemic treatment with epirubicin and tamoxifen. | Breast cancer research : BCR 20110101 |
Lipoic acid: energy metabolism and redox regulation of transcription and cell signaling. | Journal of clinical biochemistry and nutrition 20110101 |
Carbon monoxide stimulates global protein methylation via its inhibitory action on cystathionine β-synthase. | Journal of clinical biochemistry and nutrition 20110101 |
Aberrant promoter CpG methylation is a mechanism for impaired PHD3 expression in a diverse set of malignant cells. | PloS one 20110101 |
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1. | PloS one 20110101 |
Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase. | Enzyme research 20110101 |
2-hydroxyglutarate production, but not dominant negative function, is conferred by glioma-derived NADP-dependent isocitrate dehydrogenase mutations. | PloS one 20110101 |
Development of proteomics-based fungicides: new strategies for environmentally friendly control of fungal plant diseases. | International journal of molecular sciences 20110101 |
Colonization-induced host-gut microbial metabolic interaction. | mBio 20110101 |
An effective assessment of simvastatin-induced toxicity with NMR-based metabonomics approach. | PloS one 20110101 |
Integrated mutation, copy number and expression profiling in resectable non-small cell lung cancer. | BMC cancer 20110101 |
2-oxoacid metabolism in methanogenic CoM and CoB biosynthesis. | Methods in enzymology 20110101 |
Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease. | Retrovirology 20110101 |
Analysis of the ArcA regulon in anaerobically grown Salmonella enterica sv. Typhimurium. | BMC microbiology 20110101 |
Link between Aluminum and the Pathogenesis of Alzheimer's Disease: The Integration of the Aluminum and Amyloid Cascade Hypotheses. | International journal of Alzheimer's disease 20110101 |
Metabolome in schizophrenia and other psychotic disorders: a general population-based study. | Genome medicine 20110101 |
Proteomic Profiling of Mitochondrial Enzymes during Skeletal Muscle Aging. | Journal of aging research 20110101 |
Genome sequence of the stramenopile Blastocystis, a human anaerobic parasite. | Genome biology 20110101 |
MISC-1/OGC links mitochondrial metabolism, apoptosis and insulin secretion. | PloS one 20110101 |
Large-scale 13C-flux analysis reveals distinct transcriptional control of respiratory and fermentative metabolism in Escherichia coli. | Molecular systems biology 20110101 |
Hypoxia-inducible factors and the prevention of acute organ injury. | Critical care (London, England) 20110101 |
Amyloid-Beta interaction with mitochondria. | International journal of Alzheimer's disease 20110101 |
Directed culturing of microorganisms using metatranscriptomics. | mBio 20110101 |
p53 Regulates oxidative stress-mediated retrograde signaling: a novel mechanism for chemotherapy-induced cardiac injury. | PloS one 20110101 |
A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress. | BMC systems biology 20110101 |
Natural history of eukaryotic DNA methylation systems. | Progress in molecular biology and translational science 20110101 |
Revealing the beneficial effect of protease supplementation to high gravity beer fermentations using '-omics' techniques. | Microbial cell factories 20110101 |
Transcriptomic analysis of milk somatic cells in mastitis resistant and susceptible sheep upon challenge with Staphylococcus epidermidis and Staphylococcus aureus. | BMC genomics 20110101 |
A DNA pooling-based case-control study of myopia candidate genes COL11A1, COL18A1, FBN1, and PLOD1 in a Chinese population. | Molecular vision 20110101 |
A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine. | Malaria journal 20110101 |
Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. | PloS one 20110101 |
Quantal amplitude at the cone ribbon synapse can be adjusted by changes in cytosolic glutamate. | Molecular vision 20110101 |
A new crystal form of mouse thiamin pyrophosphokinase. | International journal of biochemistry and molecular biology 20110101 |
The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. | PloS one 20110101 |
Absence of aquaporin-4 in skeletal muscle alters proteins involved in bioenergetic pathways and calcium handling. | PloS one 20110101 |
More than 200 genes required for methane formation from H₂ and CO₂ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus. | Archaea (Vancouver, B.C.) 20110101 |
Design of an efficient medium for heterologous protein production in Yarrowia lipolytica: case of human interferon alpha 2b. | Microbial cell factories 20110101 |
Metabolic regulation of Escherichia coli and its phoB and phoR genes knockout mutants under phosphate and nitrogen limitations as well as at acidic condition. | Microbial cell factories 20110101 |
Do somatic mitochondrial DNA mutations contribute to Parkinson's disease? | Parkinson's disease 20110101 |
Symbolic flux analysis for genome-scale metabolic networks. | BMC systems biology 20110101 |
Identification of prognostic molecular features in the reactive stroma of human breast and prostate cancer. | PloS one 20110101 |
Protein coalitions in a core mammalian biochemical network linked by rapidly evolving proteins. | BMC evolutionary biology 20110101 |
Path finding methods accounting for stoichiometry in metabolic networks. | Genome biology 20110101 |
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma. | PloS one 20110101 |
Comparative transcriptome analysis of Bacillus subtilis responding to dissolved oxygen in adenosine fermentation. | PloS one 20110101 |
The Involvement of Glutamate Metabolism in the Resistance to Thermal, Nutritional, and Oxidative Stress in Trypanosoma cruzi. | Enzyme research 20110101 |
Novel insights into the diversity of catabolic metabolism from ten haloarchaeal genomes. | PloS one 20110101 |
L,L-diaminopimelate aminotransferase from Chlamydomonas reinhardtii: a target for algaecide development. | PloS one 20110101 |
The metabolic advantage of tumor cells. | Molecular cancer 20110101 |
Evaluation of formalin-fixed paraffin-embedded tissues in the proteomic analysis of parathyroid glands. | Proteome science 20110101 |
MicroRNA and target protein patterns reveal physiopathological features of glioma subtypes. | PloS one 20110101 |
Identification of novel soybean microRNAs involved in abiotic and biotic stresses. | BMC genomics 20110101 |
Discrimination of individuals in a general population at high-risk for alcoholic and non-alcoholic fatty liver disease based on liver stiffness: a cross section study. | BMC gastroenterology 20110101 |
Expression of hypoxia-inducible factors, regulators, and target genes in congenital diaphragmatic hernia patients. | Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 20110101 |
Multi-locus sequence typing of Salmonella enterica subsp. enterica serovar Enteritidis strains in Japan between 1973 and 2004. | Acta veterinaria Scandinavica 20110101 |
The biological deep sea hydrothermal vent as a model to study carbon dioxide capturing enzymes. | Marine drugs 20110101 |
Carotenoid β-ring hydroxylase and ketolase from marine bacteria-promiscuous enzymes for synthesizing functional xanthophylls. | Marine drugs 20110101 |
Biological responses to perfluorododecanoic acid exposure in rat kidneys as determined by integrated proteomic and metabonomic studies. | PloS one 20110101 |
Transcriptomic, proteomic and metabolomic analysis of UV-B signaling in maize. | BMC genomics 20110101 |
Primary biliary cirrhosis: family stories. | Autoimmune diseases 20110101 |
5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells. | Genome biology 20110101 |
A survey of oxidative paracatalytic reactions catalyzed by enzymes that generate carbanionic intermediates: implications for ROS production, cancer etiology, and neurodegenerative diseases. | Advances in enzymology and related areas of molecular biology 20110101 |
Economics of membrane occupancy and respiro-fermentation. | Molecular systems biology 20110101 |
Simplivariate models: uncovering the underlying biology in functional genomics data. | PloS one 20110101 |
Phenotypic variability of the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA): clinical, molecular and biochemical delineation. | Orphanet journal of rare diseases 20110101 |
Pharmacological blockade of serotonin 5-HT₇ receptor reverses working memory deficits in rats by normalizing cortical glutamate neurotransmission. | PloS one 20110101 |
Impairment of adult hippocampal neural progenitor proliferation by methamphetamine: role for nitrotyrosination. | Molecular brain 20110101 |
Directional RNA deep sequencing sheds new light on the transcriptional response of Anabaena sp. strain PCC 7120 to combined-nitrogen deprivation. | BMC genomics 20110101 |
General metabolism of Laribacter hongkongensis: a genome-wide analysis. | Cell & bioscience 20110101 |
Compartmentalized Cerebral Metabolism of [1,6-(13)C]Glucose Determined by in vivo (13)C NMR Spectroscopy at 14.1 T. | Frontiers in neuroenergetics 20110101 |
A metabolic model of the mitochondrion and its use in modelling diseases of the tricarboxylic acid cycle. | BMC systems biology 20110101 |
Mitochondrial therapeutics in Alzheimer's disease and Parkinson's disease. | Alzheimer's research & therapy 20110101 |
A minimal model for the mitochondrial rapid mode of Ca²+ uptake mechanism. | PloS one 20110101 |
Dynamic changes of the phosphoproteome in postmortem mouse brains. | PloS one 20110101 |
The role of the C8 proton of ATP in the regulation of phosphoryl transfer within kinases and synthetases. | BMC biochemistry 20110101 |
Bacterial RuBisCO is required for efficient Bradyrhizobium/Aeschynomene symbiosis. | PloS one 20110101 |
Plasmodium falciparum glutamate dehydrogenase a is dispensable and not a drug target during erythrocytic development. | Malaria journal 20110101 |
Viruses and metabolism: alterations of glucose and glutamine metabolism mediated by human cytomegalovirus. | Advances in virus research 20110101 |
The putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylation. | PloS one 20110101 |
Hypoxia-inducible factor in thyroid carcinoma. | Journal of thyroid research 20110101 |
Proteomic analysis of an Aedes albopictus cell line infected with Dengue serotypes 1 and 3 viruses. | Parasites & vectors 20110101 |
Detection of copy number variations in rice using array-based comparative genomic hybridization. | BMC genomics 20110101 |
Close Interspecies Interactions between Prokaryotes from Sulfureous Environments. | Frontiers in microbiology 20110101 |
Linking hydrothermal geochemistry to organismal physiology: physiological versatility in Riftia pachyptila from sedimented and basalt-hosted vents. | PloS one 20110101 |
Randomizing genome-scale metabolic networks. | PloS one 20110101 |
Activation of protein kinase C delta following cerebral ischemia leads to release of cytochrome C from the mitochondria via bad pathway. | PloS one 20110101 |
Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. | PloS one 20110101 |
[Astroglia proteins in the rat brain in experimental chronic hepatitis and 2-oxoglutarate effect]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101 |
Comparative analyses imply that the enigmatic Sigma factor 54 is a central controller of the bacterial exterior. | BMC genomics 20110101 |
Renal mitochondrial cytopathies. | International journal of nephrology 20110101 |
A very early-branching Staphylococcus aureus lineage lacking the carotenoid pigment staphyloxanthin. | Genome biology and evolution 20110101 |
A novel acyl-CoA beta-transaminase characterized from a metagenome. | PloS one 20110101 |
Proteomic characterization of cellular and molecular processes that enable the Nanoarchaeum equitans--Ignicoccus hospitalis relationship. | PloS one 20110101 |
Genome sequence of a mesophilic hydrogenotrophic methanogen Methanocella paludicola, the first cultivated representative of the order Methanocellales. | PloS one 20110101 |
The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue. | Genome biology 20110101 |
Epigenetics: new questions on the response to hypoxia. | International journal of molecular sciences 20110101 |
Metabolic network reconstruction and genome-scale model of butanol-producing strain Clostridium beijerinckii NCIMB 8052. | BMC systems biology 20110101 |
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth. | Molecular systems biology 20110101 |
Legionella pneumophila serogroup 3 pneumonia in a patient with low-grade 4 non-Hodgkin lymphoma: a case report. | Journal of medical case reports 20110101 |
Molecular characterization of transcriptome-wide interactions between highly pathogenic porcine reproductive and respiratory syndrome virus and porcine alveolar macrophages in vivo. | International journal of biological sciences 20110101 |
Association between markers of fatty liver disease and impaired glucose regulation in men and women from the general population: the KORA-F4-study. | PloS one 20110101 |
Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104. | PloS one 20110101 |
Deletion of UCP2 in iNOS deficient mice reduces the severity of the disease during experimental autoimmune encephalomyelitis. | PloS one 20110101 |
Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: a tangible union against chemoresistant cancer. | BMC cancer 20110101 |
The glutamine synthetase gene family in Populus. | BMC plant biology 20110101 |
Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment. | Breast cancer research : BCR 20110101 |
An Examination by Site-Directed Mutagenesis of Putative Key Residues in the Determination of Coenzyme Specificity in Clostridial NAD-Dependent Glutamate Dehydrogenase. | Enzyme research 20110101 |
Mutation of L-2,3-diaminopropionic acid synthase genes blocks staphyloferrin B synthesis in Staphylococcus aureus. | BMC microbiology 20110101 |
Recombining low homology, functionally rich regions of bacterial subtilisins by combinatorial fragment exchange. | PloS one 20110101 |
Chemometric analysis of biofluids from mice experimentally infected with Schistosoma mansoni. | Parasites & vectors 20110101 |
Analysis of the BarA/UvrY two-component system in Shewanella oneidensis MR-1. | PloS one 20110101 |
Analysis of hypoxia and hypoxia-like states through metabolite profiling. | PloS one 20110101 |
A comprehensive metabolic profile of cultured astrocytes using isotopic transient metabolic flux analysis and C-labeled glucose. | Frontiers in neuroenergetics 20110101 |
Severe encephalopathy, lactic acidosis, vegetative instability and neuropathy with 5-Fluorouracil treatment - pyrimidine degradation defect or beriberi? | Case reports in oncology 20110101 |
Unveiling novel genes upregulated by both rhBMP2 and rhBMP7 during early osteoblastic transdifferentiation of C2C12 cells. | BMC research notes 20110101 |
Detailed kinetics and regulation of mammalian 2-oxoglutarate dehydrogenase. | BMC biochemistry 20110101 |
The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR. | PloS one 20110101 |
Large-scale bi-level strain design approaches and mixed-integer programming solution techniques. | PloS one 20110101 |
Schizosaccharomyces pombe Ofd2 is a nuclear 2-oxoglutarate and iron dependent dioxygenase interacting with histones. | PloS one 20110101 |
Gene expression profile of the cartilage tissue spontaneously regenerated in vivo by using a novel double-network gel: comparisons with the normal articular cartilage. | BMC musculoskeletal disorders 20110101 |
Gibberellin A1 metabolism contributes to the control of photoperiod-mediated tuberization in potato. | PloS one 20110101 |
Chemical biology of lysine demethylases. | Current chemical genomics 20110101 |
Methods for Activity Analysis of the Proteins that Regulate Histone Methylation. | Current chemical genomics 20110101 |
D-ribose induces cellular protein glycation and impairs mouse spatial cognition. | PloS one 20110101 |
Effect of short-term ornithine alpha-ketoglutarate pretreatment on intestinal ischemia-reperfusion in rats. | Acta cirurgica brasileira 20110101 |
Differential expression of three flavanone 3-hydroxylase genes in grains and coleoptiles of wheat. | International journal of plant genomics 20110101 |
Reprogramming of Escherichia coli K-12 metabolism during the initial phase of transition from an anaerobic to a micro-aerobic environment. | PloS one 20110101 |
Modes of metabolic compensation during mitochondrial disease using the Drosophila model of ATP6 dysfunction. | PloS one 20110101 |
Temporal transcriptome changes induced by MDV in Marek's disease-resistant and -susceptible inbred chickens. | BMC genomics 20110101 |
Astrocyte-neuron lactate shuttle may boost more ATP supply to the neuron under hypoxic conditions--in silico study supported by in vitro expression data. | BMC systems biology 20110101 |
An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92. | BMC systems biology 20110101 |
MetaboHunter: an automatic approach for identification of metabolites from 1H-NMR spectra of complex mixtures. | BMC bioinformatics 20110101 |
Horizontal and vertical growth of S. cerevisiae metabolic network. | BMC evolutionary biology 20110101 |
Critical assessment of human metabolic pathway databases: a stepping stone for future integration. | BMC systems biology 20110101 |
Lipoic acid - biological activity and therapeutic potential. | Pharmacological reports : PR 20110101 |
The complete genome sequence of Thermoproteus tenax: a physiologically versatile member of the Crenarchaeota. | PloS one 20110101 |
Postprandial differences in the plasma metabolome of healthy Finnish subjects after intake of a sourdough fermented endosperm rye bread versus white wheat bread. | Nutrition journal 20110101 |
Proteomic and biochemical analyses reveal the activation of unfolded protein response, ERK-1/2 and ribosomal protein S6 signaling in experimental autoimmune myocarditis rat model. | BMC genomics 20110101 |
Activation of Hif1α by the prolylhydroxylase inhibitor dimethyoxalyglycine decreases radiosensitivity. | PloS one 20110101 |
Antitubercular effect of 8-[(4-Chloro phenyl) sulfonyl]-7-Hydroxy-4-Methyl-2H-chromen-2-One in guinea pigs. | Journal of pharmacology & pharmacotherapeutics 20110101 |
Changes in cardiac substrate transporters and metabolic proteins mirror the metabolic shift in patients with aortic stenosis. | PloS one 20110101 |
Clinical proteomics of the neglected human malarial parasite Plasmodium vivax. | PloS one 20110101 |
Mitochondrial NAD+-dependent malic enzyme from Anopheles stephensi: a possible novel target for malaria mosquito control. | Malaria journal 20110101 |
Mechanism of disruption of the Amt-GlnK complex by P(II)-mediated sensing of 2-oxoglutarate. | PloS one 20110101 |
Differential responses of the coral host and their algal symbiont to thermal stress. | PloS one 20110101 |
Paromomycin affects translation and vesicle-mediated trafficking as revealed by proteomics of paromomycin -susceptible -resistant Leishmania donovani. | PloS one 20110101 |
Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. | International journal of molecular sciences 20110101 |
Metal-induced oxidative stress and plant mitochondria. | International journal of molecular sciences 20110101 |
Inhibitors of Glioma Growth that Reveal the Tumour to the Immune System. | Clinical Medicine Insights. Oncology 20110101 |
Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells. | PloS one 20110101 |
Cancer and altered metabolism: potential importance of hypoxia-inducible factor and 2-oxoglutarate-dependent dioxygenases. | Cold Spring Harbor symposia on quantitative biology 20110101 |
Effect of intravenous GLutamine supplementation IN Trauma patients receiving enteral nutrition study protocol (GLINT Study): a prospective, blinded, randomised, placebo-controlled clinical trial. | BMJ open 20110101 |
GNC and CGA1 modulate chlorophyll biosynthesis and glutamate synthase (GLU1/Fd-GOGAT) expression in Arabidopsis. | PloS one 20110101 |
An engineered pathway for glyoxylate metabolism in tobacco plants aimed to avoid the release of ammonia in photorespiration. | BMC biotechnology 20110101 |
Potential biomarkers in mouse myocardium of doxorubicin-induced cardiomyopathy: a metabonomic method and its application. | PloS one 20110101 |
Sequence of the hyperplastic genome of the naturally competent Thermus scotoductus SA-01. | BMC genomics 20110101 |
[Importance of preservation of biophysical organization of isolated mitochondria for revealing physiological regulation of their functions]. | Biofizika 20110101 |
Biomarkers of acute kidney injury. | Journal of toxicology 20110101 |
Dynamic proteomic profiling of a unicellular cyanobacterium Cyanothece ATCC51142 across light-dark diurnal cycles. | BMC systems biology 20110101 |
In vitro prevention of cataract by Oyster Mushroom Pleurotus florida extract on isolated goat eye lens. | Indian journal of pharmacology 20110101 |
The metabolic reprogramming evoked by nitrosative stress triggers the anaerobic utilization of citrate in Pseudomonas fluorescens. | PloS one 20110101 |
A HNMR-based metabonomics study of postmenopausal osteoporosis and intervention effects of Er-Xian Decoction in ovariectomized rats. | International journal of molecular sciences 20110101 |
Radiation-induced signaling results in mitochondrial impairment in mouse heart at 4 weeks after exposure to X-rays. | PloS one 20110101 |
Genome characterization of the oleaginous fungus Mortierella alpina. | PloS one 20110101 |
Metabolic and miRNA profiling of TMV infected plants reveals biphasic temporal changes. | PloS one 20110101 |
Correlation of gene expression and protein production rate - a system wide study. | BMC genomics 20110101 |
Increasing the source/sink ratio in Vitis vinifera (cv Sangiovese) induces extensive transcriptome reprogramming and modifies berry ripening. | BMC genomics 20110101 |
Chronic deficiency of nitric oxide affects hypoxia inducible factor-1α (HIF-1α) stability and migration in human endothelial cells. | PloS one 20110101 |
[2-Oxoglutarate dehydrogenase complex and its multipoint control]. | Postepy biochemii 20110101 |
Tertiary alcohol preferred: Hydroxylation of trans-3-methyl-L-proline with proline hydroxylases. | Beilstein journal of organic chemistry 20110101 |
[Ultrastructure of coronary microvessels in conditions of heart reperfusion following prolonged ischemia while applying various methods of artificial hypothermia]. | Tsitologiia 20110101 |
Amino acids biosynthesis and nitrogen assimilation pathways: a great genomic deletion during eukaryotes evolution. | BMC genomics 20110101 |
Molecular mechanisms regulating macrophage response to hypoxia. | Frontiers in immunology 20110101 |
Integrated genomic analysis of sézary syndrome. | Genetics research international 20110101 |
Metabolite Signature during Short-Day Induced Growth Cessation in Populus. | Frontiers in plant science 20110101 |
The Plastid Outer Envelope - A Highly Dynamic Interface between Plastid and Cytoplasm. | Frontiers in plant science 20110101 |
From models to crop species: caveats and solutions for translational metabolomics. | Frontiers in plant science 20110101 |
Detecting functional groups of Arabidopsis mutants by metabolic profiling and evaluation of pleiotropic responses. | Frontiers in plant science 20110101 |
Common Motifs in the Response of Cereal Primary Metabolism to Fungal Pathogens are not Based on Similar Transcriptional Reprogramming. | Frontiers in plant science 20110101 |
The metabolite transporters of the plastid envelope: an update. | Frontiers in plant science 20110101 |
Metabolite profile changes in xylem sap and leaf extracts of strategy I plants in response to iron deficiency and resupply. | Frontiers in plant science 20110101 |
FTO Biology and Obesity: Why Do a Billion of Us Weigh 3 kg More? | Frontiers in endocrinology 20110101 |
Past, present, and future of molecular and cellular oncology. | Frontiers in oncology 20110101 |
Exploring the molecular and metabolic factors contributing to the adaptation of maize seedlings to nitrate limitation. | Frontiers in plant science 20110101 |
Complete genome sequence of Nocardiopsis dassonvillei type strain (IMRU 509). | Standards in genomic sciences 20101231 |
Structural and mechanistic studies on γ-butyrobetaine hydroxylase. | Chemistry & biology 20101222 |
IDH1 mutations are detected in 6.6% of 1414 AML patients and are associated with intermediate risk karyotype and unfavorable prognosis in adults younger than 60 years and unmutated NPM1 status. | Blood 20101216 |
von Hippel-Lindau β-domain-luciferase fusion protein as a bioluminescent hydroxyproline sensor for a hypoxia-inducible factor prolyl hydroxylase assay. | Analytical biochemistry 20101215 |
Cancer-associated IDH mutations: biomarker and therapeutic opportunities. | Oncogene 20101209 |
Reversible adenylylation of glutamine synthetase is dynamically counterbalanced during steady-state growth of Escherichia coli. | Journal of molecular biology 20101203 |
In vitro activity of antimicrobial agents against Legionella isolated from environmental water systems: first results from Turkey. | Environmental monitoring and assessment 20101201 |
Hypoxia-inducible factor regulates osteoclast-mediated bone resorption: role of angiopoietin-like 4. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20101201 |
Effects of ranolazine on fatty acid transformation in the isolated perfused rat liver. | Molecular and cellular biochemistry 20101201 |
Transcriptome atlas of glutamine family amino acid metabolism-related genes in eight regenerating liver cell types. | Cell biology international 20101201 |
Toxicometabolomics approach to urinary biomarkers for mercuric chloride (HgCl₂)-induced nephrotoxicity using proton nuclear magnetic resonance (¹H NMR) in rats. | Toxicology and applied pharmacology 20101201 |
Pyruvate carboxylation in different model systems studied by (13)C MRS. | Neurochemical research 20101201 |
Acetyl-CoA deficit in brain mitochondria in experimental thiamine deficiency encephalopathy. | Neurochemistry international 20101201 |
Dietary keto-acid feed-back on pituitary activity in gilthead sea bream: effects of oral doses of AKG. A proteomic approach. | General and comparative endocrinology 20101201 |
Flavonoid rich fraction of Dioscorea bulbifera Linn. (Yam) enhances mitochondrial enzymes and antioxidant status and thereby protects heart from isoproterenol induced myocardial infarction. | Current pharmaceutical biotechnology 20101201 |
Global gene expression analysis of Aspergillus nidulans reveals metabolic shift and transcription suppression under hypoxia. | Molecular genetics and genomics : MGG 20101201 |
Structural studies on human 2-oxoglutarate dependent oxygenases. | Current opinion in structural biology 20101201 |
Biochemical and structural characterization of recombinant hyoscyamine 6β-hydroxylase from Datura metel L. | Plant physiology and biochemistry : PPB 20101201 |
Linking the salt transcriptome with physiological responses of a salt-resistant Populus species as a strategy to identify genes important for stress acclimation. | Plant physiology 20101201 |
Structural insights into histone lysine demethylation. | Current opinion in structural biology 20101201 |
Fine quantitative trait loci mapping of carbon and nitrogen metabolism enzyme activities and seedling biomass in the maize IBM mapping population. | Plant physiology 20101201 |
Reduced placental prolyl hydroxylase 3 mRNA expression in pregnancies affected by fetal growth restriction. | BJOG : an international journal of obstetrics and gynaecology 20101201 |
Light-enhanced catalysis by pyridoxal phosphate-dependent aspartate aminotransferase. | Journal of the American Chemical Society 20101201 |
Dose dependent in vivo metabolic characteristics of titanium dioxide nanoparticles. | Journal of nanoscience and nanotechnology 20101201 |
Analysis of isocitrate dehydrogenase-1/2 gene mutations in gliomas. | Chinese medical journal 20101201 |
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1. | Cancer research 20101115 |
T3 affects expression of collagen I and collagen cross-linking in bone cell cultures. | Biochemical and biophysical research communications 20101112 |
Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase. | Nature 20101111 |
1H NMR-based metabonomic investigation of tributyl phosphate exposure in rats. | Toxicology letters 20101110 |
The nonribosomal peptide synthetase enzyme DdaD tethers N(β)-fumaramoyl-l-2,3-diaminopropionate for Fe(II)/α-ketoglutarate-dependent epoxidation by DdaC during dapdiamide antibiotic biosynthesis. | Journal of the American Chemical Society 20101110 |
A glimpse at regulation of nitrogen homeostasis. | Structure (London, England : 1993) 20101110 |
Structural underpinnings of nitrogen regulation by the prototypical nitrogen-responsive transcriptional factor NrpR. | Structure (London, England : 1993) 20101110 |
The effect of electrostatics on the marginal cooperativity of an ultrafast folding protein. | The Journal of biological chemistry 20101105 |
Multiple turnovers of the nicotino-enzyme PdxB require α-keto acids as cosubstrates. | Biochemistry 20101102 |
Methylophilus flavus sp. nov. and Methylophilus luteus sp. nov., aerobic, methylotrophic bacteria associated with plants. | International journal of systematic and evolutionary microbiology 20101101 |
Caffeic acid protects rat heart mitochondria against isoproterenol-induced oxidative damage. | Cell stress & chaperones 20101101 |
Expression of uncoupling protein 3 in mitochondria protects against stress-induced myocardial injury: a proteomic study. | Cell stress & chaperones 20101101 |
Mitochondrial involvement and erythronic acid as a novel biomarker in transaldolase deficiency. | Biochimica et biophysica acta 20101101 |
The muscle fiber type-fiber size paradox: hypertrophy or oxidative metabolism? | European journal of applied physiology 20101101 |
Genomic analysis of oceanic cyanobacterial myoviruses compared with T4-like myoviruses from diverse hosts and environments. | Environmental microbiology 20101101 |
NMR-based metabonomic analysis of the hepatotoxicity induced by combined exposure to PCBs and TCDD in rats. | Toxicology and applied pharmacology 20101101 |
Glucose promotion of GABA metabolism contributes to the stimulation of insulin secretion in β-cells. | The Biochemical journal 20101101 |
The Saccharomyces cerevisiae zinc factor protein Stb5p is required as a basal regulator of the pentose phosphate pathway. | FEMS yeast research 20101101 |
Influence of mitochondrial genome rearrangement on cucumber leaf carbon and nitrogen metabolism. | Planta 20101101 |
The influence of fruit load on the tomato pericarp metabolome in a Solanum chmielewskii introgression line population. | Plant physiology 20101101 |
Characterization and developmental expression of a glutamate decarboxylase from maritime pine. | Planta 20101101 |
The JmjC domain of Gis1 is dispensable for transcriptional activation. | FEMS yeast research 20101101 |
NrpRII mediates contacts between NrpRI and general transcription factors in the archaeon Methanosarcina mazei Gö1. | The FEBS journal 20101101 |
Relation between obesity and bone mineral density and vertebral fractures in Korean postmenopausal women. | Yonsei medical journal 20101101 |
Molecular mechanisms of 'off-on switch' of activities of human IDH1 by tumor-associated mutation R132H. | Cell research 20101101 |
Tyrosine aminotransferase: biochemical and structural properties and molecular dynamics simulations. | Protein & cell 20101101 |
[Comparative study on metabonomics and on liver and kidney toxicity of Aristolochia fangchi and Stephania tetrandra]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20101101 |
Oxygen Sensing, Cardiac Ischemia, HIF-1α and Some Emerging Concepts. | Current cardiology reviews 20101101 |
Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis. | Current cardiology reviews 20101101 |
Transamination is required for {alpha}-ketoisocaproate but not leucine to stimulate insulin secretion. | The Journal of biological chemistry 20101029 |
Carboxyl pK(a) values and acid denaturation of BBL. | Journal of molecular biology 20101022 |
Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor. | Bioorganic & medicinal chemistry letters 20101015 |
IDH2 mutations in patients with D-2-hydroxyglutaric aciduria. | Science (New York, N.Y.) 20101015 |
Prolyl hydroxylase 3 interacts with Bcl-2 to regulate doxorubicin-induced apoptosis in H9c2 cells. | Biochemical and biophysical research communications 20101015 |
Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase. | The Journal of biological chemistry 20101008 |
Histone methyl transferases and demethylases; can they link metabolism and transcription? | Cell metabolism 20101006 |
Analysis of alanine aminotransferase in various organs of soybean (Glycine max) and in dependence of different nitrogen fertilisers during hypoxic stress. | Amino acids 20101001 |
Mild reductions in cytosolic NADP-dependent isocitrate dehydrogenase activity result in lower amino acid contents and pigmentation without impacting growth. | Amino acids 20101001 |
Metabolic pathway of α-ketoglutarate in Lactobacillus sanfranciscensis and Lactobacillus reuteri during sourdough fermentation. | Journal of applied microbiology 20101001 |
2-Oxoglutaric acid administration diminishes fundectomy-induced osteopenia in pigs. | Journal of animal physiology and animal nutrition 20101001 |
Diazotrophic growth of Rhodospirillum rubrum with 2-oxoglutarate as sole carbon source affects regulation of nitrogen metabolism as well as the soluble proteome. | Research in microbiology 20101001 |
Control of AmtB-GlnK complex formation by intracellular levels of ATP, ADP, and 2-oxoglutarate. | The Journal of biological chemistry 20101001 |
Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain. | Journal of neurochemistry 20101001 |
Oxidative phosphorylation is impaired by prolonged hypoxia in breast and possibly in cervix carcinoma. | The international journal of biochemistry & cell biology 20101001 |
Dysregulation of hypoxia pathways in fumarate hydratase-deficient cells is independent of defective mitochondrial metabolism. | Human molecular genetics 20101001 |
Metabolic engineering of Escherichia coli to produce (2S, 3R, 4S)-4-hydroxyisoleucine. | Applied microbiology and biotechnology 20101001 |
An insight into the metabolic responses of ultra-small superparamagnetic particles of iron oxide using metabonomic analysis of biofluids. | Nanotechnology 20101001 |
The oxoglutarate/malate carrier of rat brain mitochondria operates by a uniport exchange mechanism. | Journal of bioenergetics and biomembranes 20101001 |
Thiamine-responsive megaloblastic anemia syndrome. | International journal of hematology 20101001 |
Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen. | The FEBS journal 20101001 |
Nitrogen anabolism underlies the importance of glutaminolysis in proliferating cells. | Cell cycle (Georgetown, Tex.) 20101001 |
Quiescent fibroblasts exhibit high metabolic activity. | PLoS biology 20101001 |
Alterations of brain and cerebellar proteomes linked to Aβ and tau pathology in a female triple-transgenic murine model of Alzheimer's disease. | Cell death & disease 20101001 |
Mechanism of selective halogenation by SyrB2: a computational study. | Journal of the American Chemical Society 20100922 |
In vitro evidence that phytanic acid compromises Na(+),K(+)-ATPase activity and the electron flow through the respiratory chain in brain cortex from young rats. | Brain research 20100917 |
Structural and functional studies of WlbA: A dehydrogenase involved in the biosynthesis of 2,3-diacetamido-2,3-dideoxy-D-mannuronic acid . | Biochemistry 20100914 |
Cooperative binding of MgATP and MgADP in the trimeric P(II) protein GlnK2 from Archaeoglobus fulgidus. | Journal of molecular biology 20100910 |
Modulating effect of Withania somnifera on TCA cycle enzymes and electron transport chain in azoxymethane-induced colon cancer in mice. | Immunopharmacology and immunotoxicology 20100901 |
L-Tryptophan catabolism by Rubrivivax benzoatilyticus JA2 occurs through indole 3-pyruvic acid pathway. | Biodegradation 20100901 |
Novel α-ketoglutarate dioxygenase tfdA-related genes are found in soil DNA after exposure to phenoxyalkanoic herbicides. | Environmental microbiology 20100901 |
Diversity in mitochondrial metabolic pathways in parasitic protists Plasmodium and Cryptosporidium. | Parasitology international 20100901 |
Composition and metabolism of carbohydrates and lipids in Sparus aurata semen and its relation to viability expressed as sperm motility when activated. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20100901 |
Virus-induced gene silencing of plastidial soluble inorganic pyrophosphatase impairs essential leaf anabolic pathways and reduces drought stress tolerance in Nicotiana benthamiana. | Plant physiology 20100901 |
Screening of a thiamine-auxotrophic yeast for alpha-ketoglutaric acid overproduction. | Letters in applied microbiology 20100901 |
Nucleotide sequence and genome organization of Dweet mottle virus and its relationship to members of the family Betaflexiviridae. | Archives of virology 20100901 |
Force field design and molecular dynamics simulations of factor-inhibiting HIF-1 and its complex with known inhibitors: implications for rational inhibitor design. | Journal of molecular graphics & modelling 20100901 |
IDH mutations in glioma and acute myeloid leukemia. | Trends in molecular medicine 20100901 |
American Association for Cancer Research Genetics and Biology of Brain Cancers 2009, December 13-15, 2009, San Diego, CA. | Journal of neuro-oncology 20100901 |
The role of mitochondria in brain aging and the effects of melatonin. | Current neuropharmacology 20100901 |
Structural analysis of WbpE from Pseudomonas aeruginosa PAO1: a nucleotide sugar aminotransferase involved in O-antigen assembly. | Biochemistry 20100824 |
Proline metabolism and microenvironmental stress. | Annual review of nutrition 20100821 |
Navigating the downhill protein folding regime via structural homologues. | Journal of the American Chemical Society 20100818 |
Interaction of JMJD6 with single-stranded RNA. | Proceedings of the National Academy of Sciences of the United States of America 20100817 |
Identification of S-nitrosated mitochondrial proteins by S-nitrosothiol difference in gel electrophoresis (SNO-DIGE): implications for the regulation of mitochondrial function by reversible S-nitrosation. | The Biochemical journal 20100815 |
Structure and reactivity of Bacillus subtilis MenD catalyzing the first committed step in menaquinone biosynthesis. | Journal of molecular biology 20100813 |
Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6. | Journal of molecular biology 20100813 |
OGFOD1, a member of the 2-oxoglutarate and iron dependent dioxygenase family, functions in ischemic signaling. | FEBS letters 20100804 |
Consumption of pasteurized human lysozyme transgenic goats' milk alters serum metabolite profile in young pigs. | Transgenic research 20100801 |
The sites and topology of mitochondrial superoxide production. | Experimental gerontology 20100801 |
Biochemical characterization of pea ornithine-delta-aminotransferase: substrate specificity and inhibition by di- and polyamines. | Biochimie 20100801 |
HIF prolyl hydroxylase-3 mediates alpha-ketoglutarate-induced apoptosis and tumor suppression. | Journal of molecular medicine (Berlin, Germany) 20100801 |
OdhI dephosphorylation kinetics during different glutamate production processes involving Corynebacterium glutamicum. | Applied microbiology and biotechnology 20100801 |
Dicarboxylate carrier-mediated glutathione transport is essential for reactive oxygen species homeostasis and normal respiration in rat brain mitochondria. | American journal of physiology. Cell physiology 20100801 |
Histidine is a source of the antioxidant, alpha-ketoglutarate, in Pseudomonas fluorescens challenged by oxidative stress. | FEMS microbiology letters 20100801 |
Network analysis of enzyme activities and metabolite levels and their relationship to biomass in a large panel of Arabidopsis accessions. | The Plant cell 20100801 |
Characterizing the metabolism of Dehalococcoides with a constraint-based model. | PLoS computational biology 20100801 |
Ornithine alpha-ketoglutarate: could it be a new therapeutic option for sarcopenia? | The journal of nutrition, health & aging 20100801 |
Metabolic changes reveal the development of schistosomiasis in mice. | PLoS neglected tropical diseases 20100801 |
Host imprints on bacterial genomes--rapid, divergent evolution in individual patients. | PLoS pathogens 20100801 |
Effect of bovine serum albumin on mitochondrial respiration in the brain and liver of mice and rats. | Bulletin of experimental biology and medicine 20100801 |
IDH1(R132) mutation identified in one human melanoma metastasis, but not correlated with metastases to the brain. | Biochemical and biophysical research communications 20100730 |
Functional dissection of a trigger enzyme: mutations of the bacillus subtilis glutamate dehydrogenase RocG that affect differentially its catalytic activity and regulatory properties. | Journal of molecular biology 20100723 |
A new P(II) protein structure identifies the 2-oxoglutarate binding site. | Journal of molecular biology 20100716 |
Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation. | Journal of immunology (Baltimore, Md. : 1950) 20100715 |
Screening and characterization of an inhibitory chemical specific to Arabidopsis gibberellin 2-oxidases. | Bioorganic & medicinal chemistry letters 20100715 |
Inhibition of hypoxia-inducible factor-targeting prolyl hydroxylase domain-containing protein 2 (PHD2) enhances matrix synthesis by human chondrocytes. | The Journal of biological chemistry 20100702 |
Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts. | The Journal of biological chemistry 20100702 |
Dietary alpha-ketoglutarate supplementation ameliorates intestinal injury in lipopolysaccharide-challenged piglets. | Amino acids 20100701 |
Cytosolic NADP-dependent isocitrate dehydrogenase contributes to redox homeostasis and the regulation of pathogen responses in Arabidopsis leaves. | Plant, cell & environment 20100701 |
Production of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) from unrelated carbon sources by metabolically engineered Escherichia coli. | Metabolic engineering 20100701 |
Neurochemical evidence that glycine induces bioenergetical dysfunction. | Neurochemistry international 20100701 |
An integrated imaging approach to the study of oxidative stress generation by mitochondrial dysfunction in living cells. | Environmental health perspectives 20100701 |
Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells. | The Biochemical journal 20100701 |
Regulation of the nitrogen transfer pathway in the arbuscular mycorrhizal symbiosis: gene characterization and the coordination of expression with nitrogen flux. | Plant physiology 20100701 |
Increased leaf size: different means to an end. | Plant physiology 20100701 |
WHO-defined 'myelodysplastic syndrome with isolated del(5q)' in 88 consecutive patients: survival data, leukemic transformation rates and prevalence of JAK2, MPL and IDH mutations. | Leukemia 20100701 |
Metabolism of organic acids, nitrogen and amino acids in chlorotic leaves of 'Honeycrisp' apple (Malus domestica Borkh) with excessive accumulation of carbohydrates. | Planta 20100701 |
IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis. | Leukemia 20100701 |
Proteomic changes associated with expression of a gene (ipt) controlling cytokinin synthesis for improving heat tolerance in a perennial grass species. | Journal of experimental botany 20100701 |
Radiolabeling and dose fixation study of oral alpha-ketoglutarate as a cyanide antidote in healthy human volunteers. | Clinical toxicology (Philadelphia, Pa.) 20100701 |
Amish microcephaly: Long-term survival and biochemical characterization. | American journal of medical genetics. Part A 20100701 |
Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus. | PLoS pathogens 20100701 |
Genome-wide analysis reveals novel genes essential for heme homeostasis in Caenorhabditis elegans. | PLoS genetics 20100701 |
[Protective effect of over-expression OGCP on HEK293 cells treated by rotenone and mutant Parkin protein]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100701 |
Two unrelated Chinese patients with hyperinsulinism /hyperammonemia (HI/HA) syndrome due to mutations in glutamate dehydrogenase gene. | Journal of pediatric endocrinology & metabolism : JPEM 20100701 |
Cyanide-induced changes in the levels of neurotransmitters in discrete brain regions of rats and their response to oral treatment with alpha-ketoglutarate. | Indian journal of experimental biology 20100701 |
2-Amino-5-methyl-pyridinium 4-carb-oxy-butano-ate. | Acta crystallographica. Section E, Structure reports online 20100701 |
Neurological disease rises from ocean to bring model for human epilepsy to life. | Toxins 20100701 |
Complete genome sequence of Thermosphaera aggregans type strain (M11TL). | Standards in genomic sciences 20100630 |
Complete genome sequence of Denitrovibrio acetiphilus type strain (N2460). | Standards in genomic sciences 20100630 |
PHD2 in tumour angiogenesis. | British journal of cancer 20100629 |
Glioma-derived mutations in IDH: from mechanism to potential therapy. | Biochemical and biophysical research communications 20100625 |
Transcriptome analysis and molecular signature of human retinal pigment epithelium. | Human molecular genetics 20100615 |
Extended ischemia prevents HIF1alpha degradation at reoxygenation by impairing prolyl-hydroxylation: role of Krebs cycle metabolites. | The Journal of biological chemistry 20100611 |
A novel signal transduction protein P(II) variant from Synechococcus elongatus PCC 7942 indicates a two-step process for NAGK-P(II) complex formation. | Journal of molecular biology 20100611 |
Sex differences in the phosphorylation of mitochondrial proteins result in reduced production of reactive oxygen species and cardioprotection in females. | Circulation research 20100611 |
Identification and functional characterization of a novel mitochondrial carrier for citrate and oxoglutarate in Saccharomyces cerevisiae. | The Journal of biological chemistry 20100604 |
Evaluation of endogenous acidic metabolic products associated with carbohydrate metabolism in tumor cells. | Cell biology and toxicology 20100601 |
Tricarboxylic acid cycle activity regulates tomato root growth via effects on secondary cell wall production. | Plant physiology 20100601 |
Quantitative proteomics: comparison of the macular Bruch membrane/choroid complex from age-related macular degeneration and normal eyes. | Molecular & cellular proteomics : MCP 20100601 |
Bacterial lifestyle in a deep-sea hydrothermal vent chimney revealed by the genome sequence of the thermophilic bacterium Deferribacter desulfuricans SSM1. | DNA research : an international journal for rapid publication of reports on genes and genomes 20100601 |
Effect of alpha-ketoglutarate and N-acetyl cysteine on cyanide-induced oxidative stress mediated cell death in PC12 cells. | Toxicology and industrial health 20100601 |
Evaluation of lysine biosynthesis as an antifungal drug target: biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies. | Eukaryotic cell 20100601 |
Enhanced transforming growth factor-beta signaling and fibrogenesis in ovine fetal skeletal muscle of obese dams at late gestation. | American journal of physiology. Endocrinology and metabolism 20100601 |
The genetics of obesity: FTO leads the way. | Trends in genetics : TIG 20100601 |
Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1. | Leukemia 20100601 |
Characterization of growth and metabolism of the haloalkaliphile Natronomonas pharaonis. | PLoS computational biology 20100601 |
Gene expression patterns of dengue virus-infected children from nicaragua reveal a distinct signature of increased metabolism. | PLoS neglected tropical diseases 20100601 |
Constraint-based model of Shewanella oneidensis MR-1 metabolism: a tool for data analysis and hypothesis generation. | PLoS computational biology 20100601 |
Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells. | The Journal of biological chemistry 20100528 |
The mitochondrial 2-oxoglutarate carrier is part of a metabolic pathway that mediates glucose- and glutamine-stimulated insulin secretion. | The Journal of biological chemistry 20100528 |
Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly. | Journal of molecular biology 20100528 |
Declining capacity of starving Delftia acidovorans MC1 to degrade phenoxypropionate herbicides correlates with oxidative modification of the initial enzyme. | Environmental science & technology 20100515 |
Analysis of expressed sequence tags from the Huperzia serrata leaf for gene discovery in the areas of secondary metabolite biosynthesis and development regulation. | Physiologia plantarum 20100501 |
Metabonomics study of urine from Sprague-Dawley rats exposed to Huang-yao-zi using (1)H NMR spectroscopy. | Journal of pharmaceutical and biomedical analysis 20100501 |
Enhanced cyclic adenosine monophosphate production by Arthrobacter A302 through rational redistribution of metabolic flux. | Bioresource technology 20100501 |
Practical strategies for suppressing hypoxia-inducible factor activity in cancer therapy. | Medical hypotheses 20100501 |
Genetic changes that increase 5-hydroxymethyl furfural resistance in ethanol-producing Escherichia coli LY180. | Biotechnology letters 20100501 |
Isethionate formation from taurine in Chromohalobacter salexigens: purification of sulfoacetaldehyde reductase. | Microbiology (Reading, England) 20100501 |
Downregulation of adipose glutathione S-transferase A4 leads to increased protein carbonylation, oxidative stress, and mitochondrial dysfunction. | Diabetes 20100501 |
Proteome of platelets in patients with coronary artery disease. | Experimental hematology 20100501 |
Atlas of rice grain filling-related metabolism under high temperature: joint analysis of metabolome and transcriptome demonstrated inhibition of starch accumulation and induction of amino acid accumulation. | Plant & cell physiology 20100501 |
Enzyme activity profiles during fruit development in tomato cultivars and Solanum pennellii. | Plant physiology 20100501 |
Crystal structures of human FIH-1 in complex with quinol family inhibitors. | Molecules and cells 20100501 |
Large scale immune profiling of infected humans and goats reveals differential recognition of Brucella melitensis antigens. | PLoS neglected tropical diseases 20100501 |
Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria. | The Plant cell 20100501 |
Integration of metabolomics and transcriptomics data to aid biomarker discovery in type 2 diabetes. | Molecular bioSystems 20100501 |
Comparative Approach of the de novo Fatty Acid Synthesis (Lipogenesis) between Ruminant and Non Ruminant Mammalian Species: From Biochemical Level to the Main Regulatory Lipogenic Genes. | Current genomics 20100501 |
Complete genome sequence of Sulfurospirillum deleyianum type strain (5175). | Standards in genomic sciences 20100430 |
Activity-based metabolomic profiling of enzymatic function: identification of Rv1248c as a mycobacterial 2-hydroxy-3-oxoadipate synthase. | Chemistry & biology 20100423 |
Oxygen activation at mononuclear nonheme iron centers: a superoxo perspective. | Inorganic chemistry 20100419 |
The FHA domain of OdhI interacts with the carboxyterminal 2-oxoglutarate dehydrogenase domain of OdhA in Corynebacterium glutamicum. | FEBS letters 20100416 |
High glucose concentrations attenuate hypoxia-inducible factor-1alpha expression and signaling in non-tumor cells. | Experimental cell research 20100415 |
Alpha-ketoisocaproic acid and leucine provoke mitochondrial bioenergetic dysfunction in rat brain. | Brain research 20100409 |
Structural basis for L-lysine feedback inhibition of homocitrate synthase. | The Journal of biological chemistry 20100402 |
Therapeutic manipulation of the HIF hydroxylases. | Antioxidants & redox signaling 20100401 |
Identification in Agrobacterium tumefaciens of the D-galacturonic acid dehydrogenase gene. | Applied microbiology and biotechnology 20100401 |
Normoxic destabilization of ATF-4 depends on proteasomal degradation. | Acta physiologica (Oxford, England) 20100401 |
Metal and substrate binding to an Fe(II) dioxygenase resolved by UV spectroscopy with global regression analysis. | Analytical biochemistry 20100401 |
Trypanosoma brucei brucei: thymine 7-hydroxylase-like proteins. | Experimental parasitology 20100401 |
Requirement of de novo synthesis of the OdhI protein in penicillin-induced glutamate production by Corynebacterium glutamicum. | Applied microbiology and biotechnology 20100401 |
Adipocyte extracellular matrix composition, dynamics and role in obesity. | Cellular and molecular life sciences : CMLS 20100401 |
The prognostic IDH1( R132 ) mutation is associated with reduced NADP+-dependent IDH activity in glioblastoma. | Acta neuropathologica 20100401 |
Disruption of BCAA metabolism in mice impairs exercise metabolism and endurance. | Journal of applied physiology (Bethesda, Md. : 1985) 20100401 |
Simultaneous quantitative determination of alpha-ketoglutaric acid and 5-hydroxymethylfurfural in human plasma by gas chromatography-mass spectrometry. | Analytical and bioanalytical chemistry 20100401 |
Use of response surface methodology in a fed-batch process for optimization of tricarboxylic acid cycle intermediates to achieve high levels of canthaxanthin from Dietzia natronolimnaea HS-1. | Journal of bioscience and bioengineering 20100401 |
Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes. | PLoS computational biology 20100401 |
Purification, crystallization and preliminary X-ray analysis of the aspartate aminotransferase of Plasmodium falciparum. | Acta crystallographica. Section F, Structural biology and crystallization communications 20100401 |
A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito. | PLoS neglected tropical diseases 20100401 |
OptForce: an optimization procedure for identifying all genetic manipulations leading to targeted overproductions. | PLoS computational biology 20100401 |
Up-regulation of the lysyl hydroxylase 2 gene by acetaminophen and isoniazid is modulated by transcription factor c-Myb. | The Journal of pharmacy and pharmacology 20100401 |
The essential toxin: impact of zinc on human health. | International journal of environmental research and public health 20100401 |
Succinylphosphonate esters are competitive inhibitors of MenD that show active-site discrimination between homologous alpha-ketoglutarate-decarboxylating enzymes. | Biochemistry 20100330 |
NMR-based metabonomic study of the sub-acute toxicity of titanium dioxide nanoparticles in rats after oral administration. | Nanotechnology 20100326 |
Metabolism, gliomas, and IDH1. | The New England journal of medicine 20100325 |
The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate. | Cancer cell 20100316 |
The genetic and metabolic signature of oncocytic transformation implicates HIF1alpha destabilization. | Human molecular genetics 20100315 |
A 'random steady-state' model for the pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase enzyme complexes. | Physical biology 20100312 |
Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers. | The Journal of biological chemistry 20100305 |
Structural insights into the prereaction state of pyruvate decarboxylase from Zymomonas mobilis . | Biochemistry 20100302 |
Mechanism of S100b release from rat cortical slices determined under basal and stimulated conditions. | Neurochemical research 20100301 |
Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse. | Bone 20100301 |
Oxygen-sensing under the influence of nitric oxide. | Cellular signalling 20100301 |
The protective effects of alpha-ketoacids against oxidative stress on rat spermatozoa in vitro. | Asian journal of andrology 20100301 |
The involvement of lipid peroxide-derived aldehydes in aluminum toxicity of tobacco roots. | Plant physiology 20100301 |
Genomic inventory and transcriptional analysis of Medicago truncatula transporters. | Plant physiology 20100301 |
Identification of circulating placental mRNA in maternal blood of pregnancies affected with fetal congenital heart diseases at the second trimester of pregnancy: implications for early molecular screening. | Prenatal diagnosis 20100301 |
In folio isotopic tracing demonstrates that nitrogen assimilation into glutamate is mostly independent from current CO2 assimilation in illuminated leaves of Brassica napus. | The New phytologist 20100301 |
Reconstruction of metabolic pathways, protein expression, and homeostasis machineries across maize bundle sheath and mesophyll chloroplasts: large-scale quantitative proteomics using the first maize genome assembly. | Plant physiology 20100301 |
Glycolysis and the tricarboxylic acid cycle are linked by alanine aminotransferase during hypoxia induced by waterlogging of Lotus japonicus. | Plant physiology 20100301 |
Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde. | Chembiochem : a European journal of chemical biology 20100301 |
Early hepatic insulin resistance in mice: a metabolomics analysis. | Molecular endocrinology (Baltimore, Md.) 20100301 |
Dual control of cytosolic metals by lysosomal transporters in lobster hepatopancreas. | The Journal of experimental biology 20100301 |
Fumarase: a mitochondrial metabolic enzyme and a cytosolic/nuclear component of the DNA damage response. | PLoS biology 20100301 |
Homeostatic interplay between bacterial cell-cell signaling and iron in virulence. | PLoS pathogens 20100301 |
The essentials of protein import in the degenerate mitochondrion of Entamoeba histolytica. | PLoS pathogens 20100301 |
DFT study of a model system for the dealkylation step catalyzed by AlkB. | Interdisciplinary sciences, computational life sciences 20100301 |
Past, present and future therapeutics for cerebellar ataxias. | Current neuropharmacology 20100301 |
Different experimental approaches in modelling cataractogenesis: An overview of selenite-induced nuclear cataract in rats. | Interdisciplinary toxicology 20100301 |
Complete genome sequence of Desulfohalobium retbaense type strain (HR(100)). | Standards in genomic sciences 20100227 |
Selective inhibitors of the JMJD2 histone demethylases: combined nondenaturing mass spectrometric screening and crystallographic approaches. | Journal of medicinal chemistry 20100225 |
Crystal structure of the PHF8 Jumonji domain, an Nepsilon-methyl lysine demethylase. | FEBS letters 20100219 |
Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding. | The New England journal of medicine 20100211 |
Protective roles of Asperosaponin VI, a triterpene saponin isolated from Dipsacus asper Wall on acute myocardial infarction in rats. | European journal of pharmacology 20100210 |
The influence of the acyl chain composition of cardiolipin on the stability of mitochondrial complexes; an unexpected effect of cardiolipin in alpha-ketoglutarate dehydrogenase and prohibitin complexes. | Journal of proteomics 20100210 |
Mechanism of substrate recognition and insight into feedback inhibition of homocitrate synthase from Thermus thermophilus. | The Journal of biological chemistry 20100205 |
Flocculation of dimorphic yeast Benjaminiella poitrasii is altered by modulation of NAD-glutamate dehydrogenase. | Bioresource technology 20100201 |
Expression and molecular characterization of the Mycobacterium tuberculosis PII protein. | Journal of biochemistry 20100201 |
Urinary metabonomic study on biochemical changes in chronic unpredictable mild stress model of depression. | Clinica chimica acta; international journal of clinical chemistry 20100201 |
Glutamine metabolism is essential for human cytomegalovirus infection. | Journal of virology 20100201 |
Alterations in brain glucose utilization accompanying elevations in blood ethanol and acetate concentrations in the rat. | Alcoholism, clinical and experimental research 20100201 |
Downregulation of pyrophosphate: D-fructose-6-phosphate 1-phosphotransferase activity in sugarcane culms enhances sucrose accumulation due to elevated hexose-phosphate levels. | Planta 20100201 |
Energy production genes sucB and ubiF are involved in persister survival and tolerance to multiple antibiotics and stresses in Escherichia coli. | FEMS microbiology letters 20100201 |
Branched-chain and aromatic amino acid catabolism into aroma volatiles in Cucumis melo L. fruit. | Journal of experimental botany 20100201 |
Structural insights into a novel histone demethylase PHF8. | Cell research 20100201 |
Interpreting metabolomic profiles using unbiased pathway models. | PLoS computational biology 20100201 |
Using NMR solvent water relaxation to investigate metalloenzyme-ligand binding interactions. | Journal of medicinal chemistry 20100128 |
Crystal structure of prolyl 4-hydroxylase from Bacillus anthracis. | Biochemistry 20100112 |
Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase. | The EMBO journal 20100106 |
Human AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sites. | DNA repair 20100102 |
Effects of alpha-ketoglutarate on neutrophil intracellular amino and alpha-keto acid profiles and ROS production. | Amino acids 20100101 |
Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases. | Biochimica et biophysica acta 20100101 |
SigC sigma factor is involved in acclimation to low inorganic carbon at high temperature in Synechocystis sp. PCC 6803. | Microbiology (Reading, England) 20100101 |
Improving baculovirus production at high cell density through manipulation of energy metabolism. | Metabolic engineering 20100101 |
Short-term effects of zinc on acetylcholine metabolism and viability of SN56 cholinergic neuroblastoma cells. | Neurochemistry international 20100101 |
Molecular cloning of lamprey uncoupling protein and assessment of its uncoupling activity using a yeast heterologous expression system. | Mitochondrion 20100101 |
Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism. | The Journal of endocrinology 20100101 |
Increased chemoresistance induced by inhibition of HIF-prolyl-hydroxylase domain enzymes. | Cancer science 20100101 |
Prevalence of loss-of-function FTO mutations in lean and obese individuals. | Diabetes 20100101 |
The 2-oxoglutarate/malate translocator mediates amino acid and storage protein biosynthesis in pea embryos. | The Plant journal : for cell and molecular biology 20100101 |
Pentanol isomer synthesis in engineered microorganisms. | Applied microbiology and biotechnology 20100101 |
Automatic policing of biochemical annotations using genomic correlations. | Nature chemical biology 20100101 |
A mutation in GDP-mannose pyrophosphorylase causes conditional hypersensitivity to ammonium, resulting in Arabidopsis root growth inhibition, altered ammonium metabolism, and hormone homeostasis. | Journal of experimental botany 20100101 |
Enzymatic and electron paramagnetic resonance studies of anabolic pyruvate synthesis by pyruvate: ferredoxin oxidoreductase from Hydrogenobacter thermophilus. | The FEBS journal 20100101 |
Mild reductions in mitochondrial NAD-dependent isocitrate dehydrogenase activity result in altered nitrate assimilation and pigmentation but do not impact growth. | Molecular plant 20100101 |
Modeling mitochondrial bioenergetics with integrated volume dynamics. | PLoS computational biology 20100101 |
Global transcriptional analysis of nitrogen fixation and ammonium repression in root-associated Pseudomonas stutzeri A1501. | BMC genomics 20100101 |
Thioredoxins function as deglutathionylase enzymes in the yeast Saccharomyces cerevisiae. | BMC biochemistry 20100101 |
Integrative analysis of the heat shock response in Aspergillus fumigatus. | BMC genomics 20100101 |
Evolution of electron transfer out of the cell: comparative genomics of six Geobacter genomes. | BMC genomics 20100101 |
Proteomic analysis of peach fruit mesocarp softening and chilling injury using difference gel electrophoresis (DIGE). | BMC genomics 20100101 |
Structural and mutational analysis of Escherichia coli AlkB provides insight into substrate specificity and DNA damage searching. | PloS one 20100101 |
Control of ATP homeostasis during the respiro-fermentative transition in yeast. | Molecular systems biology 20100101 |
Hypothalamic-specific manipulation of Fto, the ortholog of the human obesity gene FTO, affects food intake in rats. | PloS one 20100101 |
Detection and manipulation of mitochondrial reactive oxygen species in mammalian cells. | Biochimica et biophysica acta 20100101 |
Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes. | BMC genomics 20100101 |
Metabolic regulation of Escherichia coli and its gdhA, glnL, gltB, D mutants under different carbon and nitrogen limitations in the continuous culture. | Microbial cell factories 20100101 |
Placental gene expression is related to glucose metabolism and fetal cord blood levels of insulin and insulin-like growth factors in intrauterine growth restriction. | Early human development 20100101 |
Rapid determination of tricarboxylic acid cycle enzyme activities in biological samples. | BMC biochemistry 20100101 |
The Arabidopsis pop2-1 mutant reveals the involvement of GABA transaminase in salt stress tolerance. | BMC plant biology 20100101 |
In silico feasibility of novel biodegradation pathways for 1,2,4-trichlorobenzene. | BMC systems biology 20100101 |
The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing. | PloS one 20100101 |
The regulation of OXPHOS by extramitochondrial calcium. | Biochimica et biophysica acta 20100101 |
Overexpression of bacterial ethylene-forming enzyme gene in Trichoderma reesei enhanced the production of ethylene. | International journal of biological sciences 20100101 |
Transcriptional regulation of respiration in yeast metabolizing differently repressive carbon substrates. | BMC systems biology 20100101 |
Structural and functional restraints on the occurrence of single amino acid variations in human proteins. | PloS one 20100101 |
Comparative gene expression profiling between human cultured myotubes and skeletal muscle tissue. | BMC genomics 20100101 |
Neonatal maternal deprivation response and developmental changes in gene expression revealed by hypothalamic gene expression profiling in mice. | PloS one 20100101 |
Entamoeba histolytica Phosphoserine aminotransferase (EhPSAT): insights into the structure-function relationship. | BMC research notes 20100101 |
Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs. | PloS one 20100101 |
Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome. | BMC genomics 20100101 |
Effects of carboxylic acids on the uptake of non-transferrin-bound iron by astrocytes. | Neurochemistry international 20100101 |
Long-chain fatty acid combustion rate is associated with unique metabolite profiles in skeletal muscle mitochondria. | PloS one 20100101 |
Immunoproteomics analysis of the murine antibody response to vaccination with an improved Francisella tularensis live vaccine strain (LVS). | PloS one 20100101 |
Genetic analysis of central carbon metabolism unveils an amino acid substitution that alters maize NAD-dependent isocitrate dehydrogenase activity. | PloS one 20100101 |
Microarray studies on effects of Pneumocystis carinii infection on global gene expression in alveolar macrophages. | BMC microbiology 20100101 |
The unique kinetic behavior of the very large NAD-dependent glutamate dehydrogenase from Janthinobacterium lividum. | Bioscience, biotechnology, and biochemistry 20100101 |
The creation and physiological relevance of divergent hydroxylation patterns in the flavonoid pathway. | International journal of molecular sciences 20100101 |
Co-expression of Skp and FkpA chaperones improves cell viability and alters the global expression of stress response genes during scFvD1.3 production. | Microbial cell factories 20100101 |
Maternal diet-induced obesity alters mitochondrial activity and redox status in mouse oocytes and zygotes. | PloS one 20100101 |
Metabolic engineering for production of biorenewable fuels and chemicals: contributions of synthetic biology. | Journal of biomedicine & biotechnology 20100101 |
Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin inhibits the proliferation of ARPE-19 cells. | Journal of biomedical science 20100101 |
Dynamics and control of the central carbon metabolism in hepatoma cells. | BMC systems biology 20100101 |
Cancer genomics identifies determinants of tumor biology. | Genome biology 20100101 |
The expression and significance of IDH1 and p53 in osteosarcoma. | Journal of experimental & clinical cancer research : CR 20100101 |
Glutamate dehydrogenase and glutamine synthetase are regulated in response to nitrogen availability in Myocbacterium smegmatis. | BMC microbiology 20100101 |
Metabolomic and transcriptomic stress response of Escherichia coli. | Molecular systems biology 20100101 |
The complete genome sequence of Cupriavidus metallidurans strain CH34, a master survivalist in harsh and anthropogenic environments. | PloS one 20100101 |
The human collagen beta(1-O)galactosyltransferase, GLT25D1, is a soluble endoplasmic reticulum localized protein. | BMC cell biology 20100101 |
Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis. | BMC systems biology 20100101 |
Quantitative metabolomics by H-NMR and LC-MS/MS confirms altered metabolic pathways in diabetes. | PloS one 20100101 |
Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. | International journal of molecular sciences 20100101 |
Proteomics reveals a core molecular response of Pseudomonas putida F1 to acute chromate challenge. | BMC genomics 20100101 |
Carbon metabolism of enterobacterial human pathogens growing in epithelial colorectal adenocarcinoma (Caco-2) cells. | PloS one 20100101 |
The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo. | BMC medicine 20100101 |
Synthesis of 5-hydroxyectoine from ectoine: crystal structure of the non-heme iron(II) and 2-oxoglutarate-dependent dioxygenase EctD. | PloS one 20100101 |
Transcriptome sequencing and comparative transcriptome analysis of the scleroglucan producer Sclerotium rolfsii. | BMC genomics 20100101 |
Proteomic Profiling of the Dystrophin-Deficient MDX Heart Reveals Drastically Altered Levels of Key Metabolic and Contractile Proteins. | Journal of biomedicine & biotechnology 20100101 |
Transcriptional control by two leucine-responsive regulatory proteins in Halobacterium salinarum R1. | BMC molecular biology 20100101 |
Knock down of HIF-1alpha in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres. | Molecular cancer 20100101 |
Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate. | BMC genomics 20100101 |
The network of P(II) signalling protein interactions in unicellular cyanobacteria. | Advances in experimental medicine and biology 20100101 |
Switch from stress response to homeobox transcription factors in adipose tissue after profound fat loss. | PloS one 20100101 |
Selective neuronal vulnerability to oxidative stress in the brain. | Frontiers in aging neuroscience 20100101 |
Halogenated indole alkaloids from marine invertebrates. | Marine drugs 20100101 |
Structural and transcriptional analysis of plant genes encoding the bifunctional lysine ketoglutarate reductase saccharopine dehydrogenase enzyme. | BMC plant biology 20100101 |
Water buffalo genome science comes of age. | International journal of biological sciences 20100101 |
Inborn errors of energy metabolism associated with myopathies. | Journal of biomedicine & biotechnology 20100101 |
A biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients. | Molecular cancer 20100101 |
The complete genome sequence of the pathogenic intestinal spirochete Brachyspira pilosicoli and comparison with other Brachyspira genomes. | PloS one 20100101 |
Divergence involving global regulatory gene mutations in an Escherichia coli population evolving under phosphate limitation. | Genome biology and evolution 20100101 |
Compartmentalization of the Edinburgh Human Metabolic Network. | BMC bioinformatics 20100101 |
Proteomic analysis of growth phase-dependent expression of Legionella pneumophila proteins which involves regulation of bacterial virulence traits. | PloS one 20100101 |
Bcl-2 regulates HIF-1alpha protein stabilization in hypoxic melanoma cells via the molecular chaperone HSP90. | PloS one 20100101 |
Specificity of the acute tryptophan and tyrosine plus phenylalanine depletion and loading tests I. Review of biochemical aspects and poor specificity of current amino Acid formulations. | International journal of tryptophan research : IJTR 20100101 |
A global metabolic shift is linked to Salmonella multicellular development. | PloS one 20100101 |
Predicted class-I aminoacyl tRNA synthetase-like proteins in non-ribosomal peptide synthesis. | Biology direct 20100101 |
Modulation of redox homeostasis under suboptimal conditions by Arabidopsis nudix hydrolase 7. | BMC plant biology 20100101 |
Integration of metabolic databases for the reconstruction of genome-scale metabolic networks. | BMC systems biology 20100101 |
Nitric oxide: perspectives and emerging studies of a well known cytotoxin. | International journal of molecular sciences 20100101 |
Integrative inference of gene-regulatory networks in Escherichia coli using information theoretic concepts and sequence analysis. | BMC systems biology 20100101 |
Specificity of the Acute Tryptophan and Tyrosine Plus Phenylalanine Depletion and Loading Tests Part II: Normalisation of the Tryptophan and the Tyrosine Plus Phenylalanine to Competing Amino Acid Ratios in a New Control Formulation. | International journal of tryptophan research : IJTR 20100101 |
Comparative effects of selected non-caffeinated rehydration sports drinks on short-term performance following moderate dehydration. | Journal of the International Society of Sports Nutrition 20100101 |
Oxidant-NO dependent gene regulation in dogs with type I diabetes: impact on cardiac function and metabolism. | Cardiovascular diabetology 20100101 |
Identification of transcriptome induced in roots of maize seedlings at the late stage of waterlogging. | BMC plant biology 20100101 |
Oral microencapsulated live Saccharomyces cerevisiae cells for use in renal failure uremia: preparation and in vivo analysis. | Journal of biomedicine & biotechnology 20100101 |
Recent advances in the treatment of acute myeloid leukemia. | F1000 medicine reports 20100101 |
Bench-to-bedside review: Targeting antioxidants to mitochondria in sepsis. | Critical care (London, England) 20100101 |
Gut microbial gene expression in mother-fed and formula-fed piglets. | PloS one 20100101 |
A systematic investigation of Escherichia coli central carbon metabolism in response to superoxide stress. | BMC systems biology 20100101 |
Oxygen sensing in Drosophila: multiple isoforms of the prolyl hydroxylase fatiga have different capacity to regulate HIFalpha/Sima. | PloS one 20100101 |
Prevalence of primary biliary cirrhosis in adults referring hospital for annual health check-up in Southern China. | BMC gastroenterology 20100101 |
Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network. | Molecular systems biology 20100101 |
Comparative genomic analysis of pathogenic and probiotic Enterococcus faecalis isolates, and their transcriptional responses to growth in human urine. | PloS one 20100101 |
Transcriptional profile of maize roots under acid soil growth. | BMC plant biology 20100101 |
The genome of Geobacter bemidjiensis, exemplar for the subsurface clade of Geobacter species that predominate in Fe(III)-reducing subsurface environments. | BMC genomics 20100101 |
Membrane proteomic analysis of pancreatic cancer cells. | Journal of biomedical science 20100101 |
Mitochondrial preconditioning: a potential neuroprotective strategy. | Frontiers in aging neuroscience 20100101 |
The evolutionary trajectory of mitochondrial carrier family during metazoan evolution. | BMC evolutionary biology 20100101 |
Functional characterization of the incomplete phosphotransferase system (PTS) of the intracellular pathogen Brucella melitensis. | PloS one 20100101 |
Advantages of dietary, exercise-related, and therapeutic interventions to prevent and treat sarcopenia in adult patients: an update. | Clinical interventions in aging 20100101 |
Sex-different hepaticglycogen content and glucose output in rats. | BMC biochemistry 20100101 |
Complete genome and comparative analysis of the chemolithoautotrophic bacterium Oligotropha carboxidovorans OM5. | BMC genomics 20100101 |
Understanding the physiology of Lactobacillus plantarum at zero growth. | Molecular systems biology 20100101 |
[Oxidative damage of mitochondrial DNA: the result or consequence of enhanced generation of reactive oxygen species]. | Postepy biochemii 20100101 |
[The new face of factors induced by hypoxia--HIF-1 and HIF-2 and oxidative stress]. | Postepy biochemii 20100101 |
Iron-sulfur world in aerobic and hyperthermoacidophilic archaea Sulfolobus. | Archaea (Vancouver, B.C.) 20100101 |
Elementary mode analysis for the rational design of efficient succinate conversion from glycerol by Escherichia coli. | Journal of biomedicine & biotechnology 20100101 |
MetAssimulo: simulation of realistic NMR metabolic profiles. | BMC bioinformatics 20100101 |
Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence. | BMC genomics 20100101 |
Response of swine spleen to Streptococcus suis infection revealed by transcription analysis. | BMC genomics 20100101 |
Protective efficacy of natansnin, a dibenzoyl glycoside from Salvinia natans against CCl4 induced oxidative stress and cellular degeneration in rat liver. | BMC pharmacology 20100101 |
Impact of ocean acidification on energy metabolism of oyster, Crassostrea gigas--changes in metabolic pathways and thermal response. | Marine drugs 20100101 |
Coordinate Transcriptomic and Metabolomic Effects of the Insulin Sensitizer Rosiglitazone on Fundamental Metabolic Pathways in Liver, Soleus Muscle, and Adipose Tissue in Diabetic db/db Mice. | PPAR research 20100101 |
Toxicometabolomics of urinary biomarkers for human gastric cancer in a mouse model. | Journal of toxicology and environmental health. Part A 20100101 |
Deciphering the intracellular metabolism of Listeria monocytogenes by mutant screening and modelling. | BMC genomics 20100101 |
cDNA microarray gene expression profiling of hedgehog signaling pathway inhibition in human colon cancer cells. | PloS one 20100101 |
Quantitative analysis of cellular metabolic dissipative, self-organized structures. | International journal of molecular sciences 20100101 |
The aconitate hydratase family from Citrus. | BMC plant biology 20100101 |
Physiological relation between respiration activity and heterologous expression of selected benzoylformate decarboxylase variants in Escherichia coli. | Microbial cell factories 20100101 |
A multi-level study of recombinant Pichia pastoris in different oxygen conditions. | BMC systems biology 20100101 |
Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major. | Journal of nucleic acids 20100101 |
Protective effects of combination of quercetin and α-tocopherol on mitochondrial dysfunction and myocardial infarct size in isoproterenol-treated myocardial infarcted rats: biochemical, transmission electron microscopic, and macroscopic enzyme mapping evidences. | Journal of biochemical and molecular toxicology 20100101 |
Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems. | Journal of nucleic acids 20100101 |
A metabonomic comparison of urinary changes in Zucker and GK rats. | Journal of biomedicine & biotechnology 20100101 |
Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. | International journal of Alzheimer's disease 20100101 |
Review of factors affecting the growth and survival of follicular grafts. | Journal of cutaneous and aesthetic surgery 20100101 |
Short- and long-term consequences on biochemical markers after fundectomy in pigs supplemented with 3-hydroxy-3-methylbutyrate and alpha-ketoglutarate. | Berliner und Munchener tierarztliche Wochenschrift 20100101 |
Mitochondrial metabolites in tissues as indicators of metabolic alterations during hibernation. | Cryo letters 20100101 |
Some nutritional, technological and environmental advances in the use of enzymes in meat products. | Enzyme research 20100101 |
Behavioral impact of the regulation of the brain 2-oxoglutarate dehydrogenase complex by synthetic phosphonate analog of 2-oxoglutarate: implications into the role of the complex in neurodegenerative diseases. | International journal of Alzheimer's disease 20100101 |
Thiamine status in humans and content of phosphorylated thiamine derivatives in biopsies and cultured cells. | PloS one 20100101 |
Intra- and extra-cellular flux distributions of TCA and glyoxalate cycle and vancomycin production of Amycolatopsis orieantalis grown in different glycerol concentration. | Prikladnaia biokhimiia i mikrobiologiia 20100101 |
Analysis of Jmjd6 cellular localization and testing for its involvement in histone demethylation. | PloS one 20100101 |
Mice lacking Alkbh1 display sex-ratio distortion and unilateral eye defects. | PloS one 20100101 |
An incomplete TCA cycle increases survival of Salmonella Typhimurium during infection of resting and activated murine macrophages. | PloS one 20100101 |
Reconstruction and analysis of genome-scale metabolic model of a photosynthetic bacterium. | BMC systems biology 20100101 |
Induction of glucose metabolism in stimulated T lymphocytes is regulated by mitogen-activated protein kinase signaling. | PloS one 20100101 |
Metabolic response of Geobacter sulfurreducens towards electron donor/acceptor variation. | Microbial cell factories 20100101 |
The genome-scale metabolic network analysis of Zymomonas mobilis ZM4 explains physiological features and suggests ethanol and succinic acid production strategies. | Microbial cell factories 20100101 |
An empirical strategy for characterizing bacterial proteomes across species in the absence of genomic sequences. | PloS one 20100101 |
The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice. | PloS one 20100101 |
Differential proteomic analysis highlights metabolic strategies associated with balhimycin production in Amycolatopsis balhimycina chemostat cultivations. | Microbial cell factories 20100101 |
ADAR2-dependent RNA editing of GluR2 is involved in thiamine deficiency-induced alteration of calcium dynamics. | Molecular neurodegeneration 20100101 |
DNA damage induced by alkylating agents and repair pathways. | Journal of nucleic acids 20100101 |
Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast. | Molecular systems biology 20100101 |
Quantitative high-throughput screening identifies 8-hydroxyquinolines as cell-active histone demethylase inhibitors. | PloS one 20100101 |
Interaction with diurnal and circadian regulation results in dynamic metabolic and transcriptional changes during cold acclimation in Arabidopsis. | PloS one 20100101 |
Effect of gadolinium chloride on liver regeneration following thioacetamide-induced necrosis in rats. | International journal of molecular sciences 20100101 |
The Lrp family of transcription regulators in archaea. | Archaea (Vancouver, B.C.) 20100101 |
Protein markers for insulin-producing beta cells with higher glucose sensitivity. | PloS one 20100101 |
Transcriptional analysis implicates endoplasmic reticulum stress in bovine spongiform encephalopathy. | PloS one 20100101 |
Biliary epithelial apoptosis, autophagy, and senescence in primary biliary cirrhosis. | Hepatitis research and treatment 20100101 |
Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. | PloS one 20100101 |
Analysis of candidate genes for macular telangiectasia type 2. | Molecular vision 20100101 |
Identification and Partial Characterization of an L-Tyrosine Aminotransferase (TAT) from Arabidopsis thaliana. | Biochemistry research international 20100101 |
The genome sequence of Methanohalophilus mahii SLP(T) reveals differences in the energy metabolism among members of the Methanosarcinaceae inhabiting freshwater and saline environments. | Archaea (Vancouver, B.C.) 20100101 |
The effect of AmtR on growth and amino acids production in Corynebacterium glutamicum. | Prikladnaia biokhimiia i mikrobiologiia 20100101 |
Hot transcriptomics. | Archaea (Vancouver, B.C.) 20100101 |
[Hepatotoxic efects of acetaminophen. Protective properties of tryptophan-derivatives]. | Biomeditsinskaia khimiia 20100101 |
Biochemistry and occurrence of o-demethylation in plant metabolism. | Frontiers in physiology 20100101 |
The role of mitochondria for the regulation of cardiac alternans. | Frontiers in physiology 20100101 |
Role of the mitochondrion in programmed necrosis. | Frontiers in physiology 20100101 |
Amelioration of lead-induced hepatotoxicity by Allium sativum extracts in Swiss albino mice. | The Libyan journal of medicine 20100101 |
Wernicke's Encephalopathy in Colon Cancer. | Case reports in oncology 20100101 |
Biochemical and histologic changes in rats after prolonged administration of the crude aqueous extract of the leaves of Vitex grandifolia. | Pharmacognosy research 20100101 |
AMPylation: Something Old is New Again. | Frontiers in microbiology 20100101 |
Isolation and characterization of genes functionally involved in ovarian development of the giant tiger shrimp Penaeus monodon by suppression subtractive hybridization (SSH). | Genetics and molecular biology 20100101 |
Alterations in gene expression profiles correlated with cisplatin cytotoxicity in the glioma U343 cell line. | Genetics and molecular biology 20100101 |
The francisella tularensis proteome and its recognition by antibodies. | Frontiers in microbiology 20100101 |
Possible implication of oxidative stress in anti filarial effect of certain traditionally used medicinal plants in vitro against Brugia malayi microfilariae. | Pharmacognosy research 20100101 |
Animal models of Alzheimer's disease. | International journal of Alzheimer's disease 20100101 |
Chemical warfare agents. | Journal of pharmacy & bioallied sciences 20100101 |
A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli. | Advances and applications in bioinformatics and chemistry : AABC 20100101 |
Role of Mitochondrial Enzymes and Sarcoplasmic ATPase in Cardioprotection Mediated by Aqueous Extract of Desmodium gangeticum (L) DC Root on Ischemic Reperfusion Injury. | Indian journal of pharmaceutical sciences 20100101 |
Electrochemical microsensors for the detection of cadmium(II) and lead(II) ions in plants. | Sensors (Basel, Switzerland) 20100101 |
Congenital hyperinsulinism with hyperammonaemia. | BMJ case reports 20100101 |
Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. | The Journal of biological chemistry 20091218 |
A novel l-isoleucine hydroxylating enzyme, l-isoleucine dioxygenase from Bacillus thuringiensis, produces (2S,3R,4S)-4-hydroxyisoleucine. | Biochemical and biophysical research communications 20091218 |
Metabolomic analysis of biofluids from rats treated with Aconitum alkaloids using nuclear magnetic resonance and gas chromatography/time-of-flight mass spectrometry. | Analytical biochemistry 20091215 |
Small RNA-dependent expression of secondary metabolism is controlled by Krebs cycle function in Pseudomonas fluorescens. | The Journal of biological chemistry 20091211 |
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. | Nature 20091210 |
Alpha-ketoglutarate controls the ability of the Escherichia coli PII signal transduction protein to regulate the activities of NRII (NrB but does not control the binding of PII to NRII. | Biochemistry 20091208 |
Sensation and signaling of alpha-ketoglutarate and adenylylate energy charge by the Escherichia coli PII signal transduction protein require cooperation of the three ligand-binding sites within the PII trimer. | Biochemistry 20091208 |
Seed-specific expression of truncated OsGAD2 produces GABA-enriched rice grains that influence a decrease in blood pressure in spontaneously hypertensive rats. | Transgenic research 20091201 |
A novel role for fatty acid transport protein 1 in the regulation of tricarboxylic acid cycle and mitochondrial function in 3T3-L1 adipocytes. | Journal of lipid research 20091201 |
Aberrant DNA methylation profile and frequent methylation of KLK10 and OXGR1 genes in hepatocellular carcinoma. | Genes, chromosomes & cancer 20091201 |
Development and implementation of a novel assay for L-2-hydroxyglutarate dehydrogenase (L-2-HGDH) in cell lysates: L-2-HGDH deficiency in 15 patients with L-2-hydroxyglutaric aciduria. | Journal of inherited metabolic disease 20091201 |
Organ preservation solutions attenuate accumulation and nuclear translocation of hypoxia-inducible factor-1alpha in the hepatoma cell line HepG2. | Cell biochemistry and function 20091201 |
Functional characterization of a Na(+)-coupled dicarboxylate transporter from Bacillus licheniformis. | Biochimica et biophysica acta 20091201 |
Analysis of time course 1H NMR metabolomics data by multivariate curve resolution. | Magnetic resonance in chemistry : MRC 20091201 |
Cloning, expression, and enzymatic characterization of isocitrate dehydrogenase from Helicobacter pylori. | The protein journal 20091201 |
Analysis of the intermediary metabolism of a reductive chemoautotroph. | The Biological bulletin 20091201 |
The Bifidobacterium dentium Bd1 genome sequence reflects its genetic adaptation to the human oral cavity. | PLoS genetics 20091201 |
[Physiological function of alpha-ketoglutarate dehydrogenase complex in Torulopsis glabrata]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20091201 |
Host plant genome overcomes the lack of a bacterial gene for symbiotic nitrogen fixation. | Nature 20091126 |
In vitro evidence that D-serine disturbs the citric acid cycle through inhibition of citrate synthase activity in rat cerebral cortex. | Brain research 20091117 |
Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II). | Chemical communications (Cambridge, England) 20091114 |
Reactivating HIF prolyl hydroxylases under hypoxia results in metabolic catastrophe and cell death. | Oncogene 20091112 |
Missense mutations that cause Bruck syndrome affect enzymatic activity, folding, and oligomerization of lysyl hydroxylase 2. | The Journal of biological chemistry 20091106 |
Jmjd3 contributes to the control of gene expression in LPS-activated macrophages. | The EMBO journal 20091104 |
Regulation of mitochondrial dehydrogenases by calcium ions. | Biochimica et biophysica acta 20091101 |
Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. | Journal of biochemistry 20091101 |
A continuous microplate assay for sirtuins and nicotinamide-producing enzymes. | Analytical biochemistry 20091101 |
Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins. | Neurobiology of disease 20091101 |
Adsorption mechanism of Cu2+ from aqueous solution by chitosan-coated magnetic nanoparticles modified with alpha-ketoglutaric acid. | Colloids and surfaces. B, Biointerfaces 20091101 |
Hypoxia, hypoxia-inducible factors (HIF), HIF hydroxylases and oxygen sensing. | Cellular and molecular life sciences : CMLS 20091101 |
Molecular characterization of staphyloferrin B biosynthesis in Staphylococcus aureus. | Molecular microbiology 20091101 |
2-Oxoglutarate analogue inhibitors of prolyl hydroxylase domain 2. | Bioorganic & medicinal chemistry letters 20091101 |
Genetic and biochemical analysis of the serine/threonine protein kinases PknA, PknB, PknG and PknL of Corynebacterium glutamicum: evidence for non-essentiality and for phosphorylation of OdhI and FtsZ by multiple kinases. | Molecular microbiology 20091101 |
Optimizing mass spectrometric detection for ion chromatographic analysis. I. Common anions and selected organic acids. | Rapid communications in mass spectrometry : RCM 20091101 |
Metabolomics applied to diabetes research: moving from information to knowledge. | Diabetes 20091101 |
Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica. | PLoS genetics 20091101 |
Histidine-tryptophan-ketoglutarate and delayed graft function after prolonged cold ischemia. | Transplantation proceedings 20091101 |
An anaerobic-type alpha-ketoglutarate ferredoxin oxidoreductase completes the oxidative tricarboxylic acid cycle of Mycobacterium tuberculosis. | PLoS pathogens 20091101 |
Prebiotic metabolism: production by mineral photoelectrochemistry of alpha-ketocarboxylic acids in the reductive tricarboxylic acid cycle. | Astrobiology 20091101 |
Structural and functional analysis of Vitamin K2 synthesis protein MenD. | Biochemical and biophysical research communications 20091030 |
First-principles study of non-heme Fe(II) halogenase SyrB2 reactivity. | Journal of the American Chemical Society 20091014 |
Reduction of lysyl hydroxylase 3 causes deleterious changes in the deposition and organization of extracellular matrix. | The Journal of biological chemistry 20091009 |
D-xylose degradation pathway in the halophilic archaeon Haloferax volcanii. | The Journal of biological chemistry 20091002 |
Metabolite regulation of the interaction between Arabidopsis thaliana PII and N-acetyl-l-glutamate kinase. | Biochemical and biophysical research communications 20091002 |
Enhanced production of poly (gamma-glutamic acid) from Bacillus licheniformis NCIM 2324 by using metabolic precursors. | Applied biochemistry and biotechnology 20091001 |
Ganoderma lucidum (Fr.) P. Karst enhances activities of heart mitochondrial enzymes and respiratory chain complexes in the aged rat. | Biogerontology 20091001 |
Preservation of the in vivo state of mitochondrial network for ex vivo physiological study of mitochondria. | The international journal of biochemistry & cell biology 20091001 |
Metabolic control analysis in a cellular model of elevated MAO-B: relevance to Parkinson's disease. | Neurotoxicity research 20091001 |
Colloidal nanoparticles as a wireless booster for electroenzymatic reactions. | Small (Weinheim an der Bergstrasse, Germany) 20091001 |
Dual role of poly(ADP-ribose) glycohydrolase in the regulation of cell death in oxidatively stressed A549 cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20091001 |
Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition. | Free radical biology & medicine 20091001 |
Aspergillus terreus NADP-glutamate dehydrogenase is kinetically distinct from the allosteric enzyme of other Aspergilli. | Mycological research 20091001 |
Direct effects of corticosterone on ATP production by mitochondria from immortalized hypothalamic GT1-7 neurons. | The Journal of steroid biochemistry and molecular biology 20091001 |
The Pitx2c N-terminal domain is a critical interaction domain required for asymmetric morphogenesis. | Developmental dynamics : an official publication of the American Association of Anatomists 20091001 |
Decreased transketolase activity contributes to impaired hippocampal neurogenesis induced by thiamine deficiency. | Journal of neurochemistry 20091001 |
Resolving the role of plant glutamate dehydrogenase. I. In vivo real time nuclear magnetic resonance spectroscopy experiments. | Plant & cell physiology 20091001 |
Neuronal apoptosis by prolyl hydroxylation: implication in nervous system tumours and the Warburg conundrum. | Journal of cellular and molecular medicine 20091001 |
Glutamate metabolic pathways and retinal function. | Journal of neurochemistry 20091001 |
Role of plant glyoxylate reductases during stress: a hypothesis. | The Biochemical journal 20091001 |
Structure-based predictive models for allosteric hot spots. | PLoS computational biology 20091001 |
Chemical and functional aspects of posttranslational modification of proteins. | Acta naturae 20091001 |
Experimental evidence that ornithine and homocitrulline disrupt energy metabolism in brain of young rats. | Brain research 20090929 |
Complete genome sequence of Methanoculleus marisnigri Romesser et al. 1981 type strain JR1. | Standards in genomic sciences 20090929 |
Complete genome sequence of Methanocorpusculum labreanum type strain Z. | Standards in genomic sciences 20090929 |
Production of bioactive, post-translationally modified, heterotrimeric, human recombinant type-I collagen in transgenic tobacco. | Biomacromolecules 20090914 |
The crystal structure of an algal prolyl 4-hydroxylase complexed with a proline-rich peptide reveals a novel buried tripeptide binding motif. | The Journal of biological chemistry 20090911 |
SDH5 mutations and familial paraganglioma: somewhere Warburg is smiling. | Cancer cell 20090908 |
Acute toxicity of some synthetic cyanogens in rats and their response to oral treatment with alpha-ketoglutarate. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090901 |
Antitumor effects of 2-oxoglutarate through inhibition of angiogenesis in a murine tumor model. | Cancer science 20090901 |
Identification of the putative tumor suppressor Nit2 as omega-amidase, an enzyme metabolically linked to glutamine and asparagine transamination. | Biochimie 20090901 |
Primary biliary cirrhosis. | Seminars in immunopathology 20090901 |
Pyruvate into lactate and back: from the Warburg effect to symbiotic energy fuel exchange in cancer cells. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090901 |
Discovery of proteinaceous N-modification in lysine biosynthesis of Thermus thermophilus. | Nature chemical biology 20090901 |
Metabolic discrimination of Catharanthus roseus calli according to their relative locations using (1)H-NMR and principal component analysis. | Bioscience, biotechnology, and biochemistry 20090901 |
[Metabonomic study on the effects of allicin on rats]. | Yao xue xue bao = Acta pharmaceutica Sinica 20090901 |
Lipoic acid synthesis and attachment in yeast mitochondria. | The Journal of biological chemistry 20090828 |
Metabolic control exerted by the 2-oxoglutarate dehydrogenase reaction: a cross-kingdom comparison of the crossroad between energy production and nitrogen assimilation. | The Biochemical journal 20090827 |
Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. | The Journal of biological chemistry 20090821 |
Hypoxia-inducible factor prolyl-4-hydroxylase PHD2 protein abundance depends on integral membrane anchoring of FKBP38. | The Journal of biological chemistry 20090821 |
Assay and purification of omega-amidase/Nit2, a ubiquitously expressed putative tumor suppressor, that catalyzes the deamidation of the alpha-keto acid analogues of glutamine and asparagine. | Analytical biochemistry 20090815 |
Proline oxidase functions as a mitochondrial tumor suppressor in human cancers. | Cancer research 20090815 |
Flexible heteroarotinoid (Flex-Het) SHetA2 inhibits angiogenesis in vitro and in vivo. | Investigational new drugs 20090801 |
Differential effects of bone morphogenetic protein-2 and transforming growth factor-beta1 on gene expression of collagen-modifying enzymes in human adipose tissue-derived mesenchymal stem cells. | Tissue engineering. Part A 20090801 |
Preventive effect of S-allyl cysteine sulphoxide (Alliin) on mitochondrial dysfunction in normal and isoproterenol induced cardiotoxicity in male Wistar rats: a histopathological study. | Molecular and cellular biochemistry 20090801 |
Central metabolism in Mycobacterium smegmatis during the transition from O2-rich to O2-poor conditions as studied by isotopomer-assisted metabolite analysis. | Biotechnology letters 20090801 |
Functional characterization of stage-specific aminotransferases from trypanosomatids. | Molecular and biochemical parasitology 20090801 |
Chemoorganoheterotrophic growth of Nitrosomonas europaea and Nitrosomonas eutropha. | Current microbiology 20090801 |
Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors. | Journal of neuro-oncology 20090801 |
Palladium alpha-lipoic acid complex formulation enhances activities of Krebs cycle dehydrogenases and respiratory complexes I-IV in the heart of aged rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090801 |
Specificity versus catalytic potency: The role of threonine 44 in Escherichia coli dihydrodipicolinate synthase mediated catalysis. | Biochimie 20090801 |
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. | Nature chemical biology 20090801 |
Effects of structural analogues of the substrate and allosteric regulator of the human mitochondrial NAD(P)+-dependent malic enzyme. | Bioorganic & medicinal chemistry 20090801 |
Efficacy and safety of ornithine alpha-ketoglutarate in heel pressure ulcers in elderly patients: results of a randomized controlled trial. | The journal of nutrition, health & aging 20090801 |
Obesity and metabolic syndrome in histone demethylase JHDM2a-deficient mice. | Genes to cells : devoted to molecular & cellular mechanisms 20090801 |
Radiation metabolomics. 3. Biomarker discovery in the urine of gamma-irradiated rats using a simplified metabolomics protocol of gas chromatography-mass spectrometry combined with random forests machine learning algorithm. | Radiation research 20090801 |
Drilling for energy in mitochondrial disease. | Archives of neurology 20090801 |
Human NARP mitochondrial mutation metabolism corrected with alpha-ketoglutarate/aspartate: a potential new therapy. | Archives of neurology 20090801 |
[Nephrotoxicity study of Aristolochia fangchi in rats by metabonomics]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20090801 |
A mouse model for the metabolic effects of the human fat mass and obesity associated FTO gene. | PLoS genetics 20090801 |
On the accessibility of adaptive phenotypes of a bacterial metabolic network. | PLoS computational biology 20090801 |
Modifying the alkylglucosinolate profile in Arabidopsis thaliana alters the tritrophic interaction with the herbivore Brevicoryne brassicae and parasitoid Diaeretiella rapae. | Journal of chemical ecology 20090801 |
Phosphono analogues of 2-oxoglutarate protect cerebellar granule neurons upon glutamate excitotoxicity. | Annals of the New York Academy of Sciences 20090801 |
Integrative normalization and comparative analysis for metabolic fingerprinting by comprehensive two-dimensional gas chromatography-time-of-flight mass spectrometry. | Analytical chemistry 20090715 |
Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases. | Structure (London, England : 1993) 20090715 |
Origin of the correlation of the rate constant of substrate hydroxylation by nonheme iron(IV)-oxo complexes with the bond-dissociation energy of the C-H bond of the substrate. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090706 |
Chemically assisted microbial production of succinic acid by the yeast Yarrowia lipolytica grown on ethanol. | Applied microbiology and biotechnology 20090701 |
Metabonomic identification of novel biomarkers in doxorubicin cardiotoxicity and protective effect of the natural antioxidant oleuropein. | NMR in biomedicine 20090701 |
The role of respiratory donor enzymes in Campylobacter jejuni host colonization and physiology. | Microbial pathogenesis 20090701 |
A functional analysis of the pyrimidine catabolic pathway in Arabidopsis. | The New phytologist 20090701 |
Regulation and function of proline oxidase under nutrient stress. | Journal of cellular biochemistry 20090701 |
A redox-mediated modulation of stem bolting in transgenic Nicotiana sylvestris differentially expressing the external mitochondrial NADPH dehydrogenase. | Plant physiology 20090701 |
Subcellular localization and expression of multiple tomato gamma-aminobutyrate transaminases that utilize both pyruvate and glyoxylate. | Journal of experimental botany 20090701 |
Analysis of achromobactin biosynthesis by Pseudomonas syringae pv. syringae B728a. | Journal of bacteriology 20090701 |
Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response. | Journal of proteome research 20090701 |
Characterization of a robust enzymatic assay for inhibitors of 2-oxoglutarate-dependent hydroxylases. | Journal of biomolecular screening 20090701 |
Metabonomic study of ochratoxin a toxicity in rats after repeated administration: phenotypic anchoring enhances the ability for biomarker discovery. | Chemical research in toxicology 20090701 |
Building disease-specific drug-protein connectivity maps from molecular interaction networks and PubMed abstracts. | PLoS computational biology 20090701 |
Linkage between circadian clock and tricarboxylic acid cycle in Arabidopsis. | Plant signaling & behavior 20090701 |
Protective role of alpha-ketoglutarate against massive doses of cyanide in rats. | Journal of environmental biology 20090701 |
Biochemical characterization of the prolyl 3-hydroxylase 1.cartilage-associated protein.cyclophilin B complex. | The Journal of biological chemistry 20090626 |
N-acetyl-L-glutamate kinase (NAGK) from oxygenic phototrophs: P(II) signal transduction across domains of life reveals novel insights in NAGK control. | Journal of molecular biology 20090619 |
A game with many players: control of gdh transcription in Corynebacterium glutamicum. | Journal of biotechnology 20090615 |
Use of an osmium complex as a universal luminescent probe for enzymatic reactions. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090615 |
TIA nuclear proteins regulate the alternate splicing of lysyl hydroxylase 2. | The Journal of investigative dermatology 20090601 |
Effects of indole-3-acetic acid on Sinorhizobium meliloti survival and on symbiotic nitrogen fixation and stem dry weight production. | Applied microbiology and biotechnology 20090601 |
From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. | Microbiology (Reading, England) 20090601 |
Determination of phosphorylation sites for NADP-specific isocitrate dehydrogenase from mycobacterium tuberculosis. | Journal of biomolecular structure & dynamics 20090601 |
Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids. | Cell cycle (Georgetown, Tex.) 20090601 |
Bruck syndrome: osteogenesis imperfecta and arthrogryposis multiplex congenita. | Annals of tropical paediatrics 20090601 |
Substrate-triggered formation and remarkable stability of the C-H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2. | Biochemistry 20090526 |
The prolyl 3-hydroxylases P3H2 and P3H3 are novel targets for epigenetic silencing in breast cancer. | British journal of cancer 20090519 |
A stable and selective electrochemical biosensor for the liver enzyme alanine aminotransferase (ALT). | Biosensors & bioelectronics 20090515 |
Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. | Science (New York, N.Y.) 20090515 |
Application of a proteolysis/mass spectrometry method for investigating the effects of inhibitors on hydroxylase structure. | Journal of medicinal chemistry 20090514 |
Aluminum-induced defective mitochondrial metabolism perturbs cytoskeletal dynamics in human astrocytoma cells. | Journal of neuroscience research 20090501 |
Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype. | International journal of cancer 20090501 |
Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. | Free radical biology & medicine 20090501 |
Directed evolution and rational approaches to improving Streptomyces clavuligerus deacetoxycephalosporin C synthase for cephalosporin production. | Journal of industrial microbiology & biotechnology 20090501 |
Catabolism of nutritionally essential amino acids in developing porcine enterocytes. | Amino acids 20090501 |
Phosphate accumulation of Acetobacter xylinum. | Archives of microbiology 20090501 |
Cloning and characterization of Rhodotorula glutinis thymine hydroxylase. | Chemical research in toxicology 20090501 |
Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan. | Experimental gerontology 20090501 |
Mild reduction in the activity of the alpha-ketoglutarate dehydrogenase complex elevates GABA shunt and glycolysis. | Journal of neurochemistry 20090501 |
Inhibition of the alpha-ketoglutarate dehydrogenase-mediated reactive oxygen species generation by lipoic acid. | Journal of neurochemistry 20090501 |
Protective effects of compound FLZ, a novel synthetic analogue of squamosamide, on beta-amyloid-induced rat brain mitochondrial dysfunction in vitro. | Acta pharmacologica Sinica 20090501 |
Synthetic regulators of the 2-oxoglutarate oxidative decarboxylation alleviate the glutamate excitotoxicity in cerebellar granule neurons. | Biochemical pharmacology 20090501 |
Multiple osteoporosis susceptibility genes on chromosome 1p36 in Chinese. | Bone 20090501 |
Biosensor based on glutamate dehydrogenase immobilized in chitosan for the determination of ammonium in water samples. | Analytical biochemistry 20090501 |
Mitochondria and energetic depression in cell pathophysiology. | International journal of molecular sciences 20090501 |
A non-heme iron-mediated chemical demethylation in DNA and RNA. | Accounts of chemical research 20090421 |
Branched-chain 2-oxoacid transamination increases GABA-shunt metabolism and insulin secretion in isolated islets. | The Biochemical journal 20090415 |
Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism. | Structure (London, England : 1993) 20090415 |
Cancer. Puzzling patterns of predisposition. | Science (New York, N.Y.) 20090410 |
Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha. | Science (New York, N.Y.) 20090410 |
Structural analysis of an open active site conformation of nonheme iron halogenase CytC3. | Journal of the American Chemical Society 20090408 |
L: -2-Hydroxyglutaric aciduria, a disorder of metabolite repair. | Journal of inherited metabolic disease 20090401 |
Neuronal mitochondrial toxicity of malondialdehyde: inhibitory effects on respiratory function and enzyme activities in rat brain mitochondria. | Neurochemical research 20090401 |
2007 annual progress report synopsis of the Center for Structures of Membrane Proteins. | Journal of structural and functional genomics 20090401 |
Fast isotopic exchange between mitochondria and cytosol in brain revealed by relayed 13C magnetization transfer spectroscopy. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20090401 |
Development of a defined medium for Clostridium scatologenes ATCC 25775. | Letters in applied microbiology 20090401 |
Differential expression of a virulence factor in pathogenic and non-pathogenic mycobacteria. | Molecular microbiology 20090401 |
Triggering and amplification of insulin secretion by dimethyl alpha-ketoglutarate, a membrane permeable alpha-ketoglutarate analogue. | European journal of pharmacology 20090401 |
Biochemical characterization, mitochondrial localization, expression, and potential functions for an Arabidopsis gamma-aminobutyrate transaminase that utilizes both pyruvate and glyoxylate. | Journal of experimental botany 20090401 |
Measurement of D: -2-hydroxyglutarate dehydrogenase activity in cell homogenates derived from D: -2-hydroxyglutaric aciduria patients. | Journal of inherited metabolic disease 20090401 |
Dual mechanism of brain injury and novel treatment strategy in maple syrup urine disease. | Brain : a journal of neurology 20090401 |
Novel human pathological mutations. Gene symbol: PLOD1. Disease: Ehlers-Danlos syndrome type VIA, kyphoscoliotic type. | Human genetics 20090401 |
Alpha-ketoglutarate protects the liver of piglets exposed during prenatal life to chronic excess of dexamethasone from metabolic and structural changes. | Journal of animal physiology and animal nutrition 20090401 |
Prophylaxis with alpha-lipoic acid against lipopolysaccharide-induced brain injury in rats. | Archivum immunologiae et therapiae experimentalis 20090401 |
Over-expression of a tomato N-acetyl-L-glutamate synthase gene (SlNAGS1) in Arabidopsis thaliana results in high ornithine levels and increased tolerance in salt and drought stresses. | Journal of experimental botany 20090401 |
A regulated response to impaired respiration slows behavioral rates and increases lifespan in Caenorhabditis elegans. | PLoS genetics 20090401 |
Mapping gene associations in human mitochondria using clinical disease phenotypes. | PLoS computational biology 20090401 |
Intra-mitochondrial poly(ADP-ribosyl)ation: potential role for alpha-ketoglutarate dehydrogenase. | Mitochondrion 20090401 |
Control and regulation of integrated mitochondrial function in metabolic and transport networks. | International journal of molecular sciences 20090401 |
Bidirectionality and compartmentation of metabolic fluxes are revealed in the dynamics of isotopomer networks. | International journal of molecular sciences 20090401 |
Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing. | International journal of molecular sciences 20090401 |
Application of 1H NMR-based metabonomics in the study of metabolic profiling of human hepatocellular carcinoma and liver cirrhosis. | Cancer science 20090401 |
Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins. | The Journal of biological chemistry 20090327 |
Structural insights of the MenD from Escherichia coli reveal ThDP affinity. | Biochemical and biophysical research communications 20090320 |
Direct and continuous assay for prolyl 4-hydroxylase. | Analytical biochemistry 20090315 |
Manganese (II) induces chemical hypoxia by inhibiting HIF-prolyl hydroxylase: implication in manganese-induced pulmonary inflammation. | Toxicology and applied pharmacology 20090315 |
Calcium signaling in brain mitochondria: interplay of malate aspartate NADH shuttle and calcium uniporter/mitochondrial dehydrogenase pathways. | The Journal of biological chemistry 20090313 |
In vitro interactions between the PII proteins and the nitrogenase regulatory enzymes dinitrogenase reductase ADP-ribosyltransferase (DraT) and dinitrogenase reductase-activating glycohydrolase (DraG) in Azospirillum brasilense. | The Journal of biological chemistry 20090313 |
Oxidative stress mediated cytotoxicity of cyanide in LLC-MK2 cells and its attenuation by alpha-ketoglutarate and N-acetyl cysteine. | Toxicology letters 20090310 |
The glycosyltransferase activities of lysyl hydroxylase 3 (LH3) in the extracellular space are important for cell growth and viability. | Journal of cellular and molecular medicine 20090301 |
Proteomics-based identification of novel factor inhibiting hypoxia-inducible factor (FIH) substrates indicates widespread asparaginyl hydroxylation of ankyrin repeat domain-containing proteins. | Molecular & cellular proteomics : MCP 20090301 |
Alpha-ketoglutarate abrogates the nuclear localization of HIF-1alpha in aluminum-exposed hepatocytes. | Biochimie 20090301 |
Effect of Ganoderma lucidum on the activities of mitochondrial dehydrogenases and complex I and II of electron transport chain in the brain of aged rats. | Experimental gerontology 20090301 |
Thiamine deficiency-related brain dysfunction in chronic liver failure. | Metabolic brain disease 20090301 |
AcsD catalyzes enantioselective citrate desymmetrization in siderophore biosynthesis. | Nature chemical biology 20090301 |
Arginine kinase from Litopenaeus vannamei: cloning, expression and catalytic properties. | Fish & shellfish immunology 20090301 |
Philosophical basis and some historical aspects of systems biology: from Hegel to Noble - applications for bioenergetic research. | International journal of molecular sciences 20090301 |
On-chip microfluidic systems for determination of L-glutamate based on enzymatic recycling of substrate. | Biomicrofluidics 20090301 |
Characterization of novel 2-oxoglutarate dependent dioxygenases converting L-proline to cis-4-hydroxy-l-proline. | Biochemical and biophysical research communications 20090220 |
Oxaloacetate restores the long-term potentiation impaired in rat hippocampus CA1 region by 2-vessel occlusion. | European journal of pharmacology 20090214 |
Bone mineral density and bone turnover in relation to serum leptin, alpha-ketoglutarate and sex steroids in overweight and obese postmenopausal women. | Clinical endocrinology 20090201 |
Toxicity of select organic acids to the slightly thermophilic acidophile Acidithiobacillus caldus. | Environmental toxicology and chemistry 20090201 |
Dynamic protein methylation in chromatin biology. | Cellular and molecular life sciences : CMLS 20090201 |
Removal of Cu2+ from aqueous solution by chitosan-coated magnetic nanoparticles modified with alpha-ketoglutaric acid. | Journal of colloid and interface science 20090201 |
Iron- and 2-oxoglutarate-dependent dioxygenases: an emerging group of molecular targets for nickel toxicity and carcinogenicity. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20090201 |
Inactivation of GABA transaminase by 3-chloro-1-(4-hydroxyphenyl)propan-1-one. | Bioorganic & medicinal chemistry letters 20090201 |
Prolyl hydroxylases as regulators of cell metabolism. | Biochemical Society transactions 20090201 |
Carnitine in the treatment of valproic acid-induced toxicity. | Clinical toxicology (Philadelphia, Pa.) 20090201 |
Sugar regulation of plastid reversion in citrus epicarp is mediated through organic acid metabolism. | Pakistan journal of biological sciences : PJBS 20090201 |
alpha-Ketoglutarate dehydrogenase contributes to production of reactive oxygen species in glutamate-stimulated hippocampal neurons in situ. | Neuroscience 20090123 |
Reconstitution of Escherichia coli glutamine synthetase adenylyltransferase from N-terminal and C-terminal fragments of the enzyme. | Biochemistry 20090120 |
Kinetic characterization and identification of a novel inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 using a time-resolved fluorescence resonance energy transfer-based assay technology. | Analytical biochemistry 20090115 |
Role of the mitochondrial sodium/calcium exchanger in neuronal physiology and in the pathogenesis of neurological diseases. | Progress in neurobiology 20090112 |
Robust glycogen shunt activity in astrocytes: Effects of glutamatergic and adrenergic agents. | Neuroscience 20090112 |
Carbon dioxide: a waste product in the catalytic cycle of alpha-ketoglutarate dependent halogenases prevents the formation of hydroxylated by-products. | The journal of physical chemistry. B 20090108 |
Oxygen sensors at the crossroad of metabolism. | Cell metabolism 20090107 |
The phosphatidylinositol-protein nanocomplex as a new biosensor for ecological monitoring and clinical diagnostic. | Biosensors & bioelectronics 20090101 |
Mechanism of cancer cell adaptation to metabolic stress: proteomics identification of a novel thyroid hormone-mediated gastric carcinogenic signaling pathway. | Molecular & cellular proteomics : MCP 20090101 |
Genetic manipulation of lysine catabolism in maize kernels. | Plant molecular biology 20090101 |
Periplasmic cold expression and one-step purification of human dihydrolipoamide dehydrogenase. | Protein expression and purification 20090101 |
Effect of odhA overexpression and odhA antisense RNA expression on Tween-40-triggered glutamate production by Corynebacterium glutamicum. | Applied microbiology and biotechnology 20090101 |
Effect of dietary alpha-ketoglutarate on blood lipid profile during hypercholesterolaemia in rats. | Scandinavian journal of clinical and laboratory investigation 20090101 |
Influence of all-trans-retinoic acid on oxoglutarate carrier via retinoylation reaction. | Biochimica et biophysica acta 20090101 |
Nanoparticle-supported multi-enzyme biocatalysis with in situ cofactor regeneration. | Journal of biotechnology 20090101 |
A pathway-specific microarray analysis highlights the complex and co-ordinated transcriptional networks of the developing grain of field-grown barley. | Journal of experimental botany 20090101 |
How mitochondria produce reactive oxygen species. | The Biochemical journal 20090101 |
Peroxidative damage of mitochondrial respiration is substrate-dependent. | Physiological research 20090101 |
Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function. | Chemical research in toxicology 20090101 |
Role of calcium in acclimation of the cyanobacterium Synechococcus elongatus PCC 7942 to nitrogen starvation. | Microbiology (Reading, England) 20090101 |
Synthetic control of a fitness tradeoff in yeast nitrogen metabolism. | Journal of biological engineering 20090101 |
Metabolic engineering of a reduced-genome strain of Escherichia coli for L-threonine production. | Microbial cell factories 20090101 |
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases. | BMC medical genomics 20090101 |
Differential global and extra-cellular matrix focused gene expression patterns between normal and glaucomatous human lamina cribrosa cells. | Molecular vision 20090101 |
Imbalanced lignin biosynthesis promotes the sexual reproduction of homothallic oomycete pathogens. | PLoS pathogens 20090101 |
Update of cell damage mechanisms in thiamine deficiency: focus on oxidative stress, excitotoxicity and inflammation. | Alcohol and alcoholism (Oxford, Oxfordshire) 20090101 |
Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. | PloS one 20090101 |
Organised genome dynamics in the Escherichia coli species results in highly diverse adaptive paths. | PLoS genetics 20090101 |
Comparative transcriptomic analysis of Porphyromonas gingivalis biofilm and planktonic cells. | BMC microbiology 20090101 |
Coordinated concentration changes of transcripts and metabolites in Saccharomyces cerevisiae. | PLoS computational biology 20090101 |
Inter- and intra-individual variations of urinary endogenous metabolites in healthy male college students using (1)H NMR spectroscopy. | Clinical chemistry and laboratory medicine 20090101 |
Global transcriptional response of Saccharomyces cerevisiae to the deletion of SDH3. | BMC systems biology 20090101 |
Analysis on relationship between extreme pathways and correlated reaction sets. | BMC bioinformatics 20090101 |
LC/MS-based quantitative proteomic analysis of paraffin-embedded archival melanomas reveals potential proteomic biomarkers associated with metastasis. | PloS one 20090101 |
Hypoxia. The role of hypoxia and HIF-dependent signalling events in rheumatoid arthritis. | Arthritis research & therapy 20090101 |
Hypoxia. HIF-mediated articular chondrocyte function: prospects for cartilage repair. | Arthritis research & therapy 20090101 |
Acid production by oral strains of Candida albicans and lactobacilli. | Caries research 20090101 |
Genome sequence of the pathogenic intestinal spirochete brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine. | PloS one 20090101 |
New therapeutic approach to Tourette Syndrome in children based on a randomized placebo-controlled double-blind phase IV study of the effectiveness and safety of magnesium and vitamin B6. | Trials 20090101 |
The photosynthetic apparatus and its regulation in the aerobic gammaproteobacterium Congregibacter litoralis gen. nov., sp. nov. | PloS one 20090101 |
Hypoxia. Regulation of NFkappaB signalling during inflammation: the role of hydroxylases. | Arthritis research & therapy 20090101 |
Metabolic profiles in urine reflect nephrotoxicity of sirolimus and cyclosporine following rat kidney transplantation. | Nephron. Experimental nephrology 20090101 |
Identification of IbeR as a stationary-phase regulator in meningitic Escherichia coli K1 that carries a loss-of-function mutation in rpoS. | Journal of biomedicine & biotechnology 20090101 |
Transcriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes. | BMC genomics 20090101 |
Connecting extracellular metabolomic measurements to intracellular flux states in yeast. | BMC systems biology 20090101 |
The impact of surfactant protein-A on ozone-induced changes in the mouse bronchoalveolar lavage proteome. | Proteome science 20090101 |
Potential mechanisms of muscle mitochondrial dysfunction in aging and obesity and cellular consequences. | International journal of molecular sciences 20090101 |
Host iron binding proteins acting as niche indicators for Neisseria meningitidis. | PloS one 20090101 |
Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane. | PloS one 20090101 |
Choreography of the transcriptome, photophysiology, and cell cycle of a minimal photoautotroph, prochlorococcus. | PloS one 20090101 |
Erythropoiesis stimulating agents and techniques: a challenge for doping analysts. | Current medicinal chemistry 20090101 |
Chapter 17. Siderophore biosynthesis a substrate specificity assay for nonribosomal peptide synthetase-independent siderophore synthetases involving trapping of acyl-adenylate intermediates with hydroxylamine. | Methods in enzymology 20090101 |
In vitro histone demethylase assays. | Methods in molecular biology (Clifton, N.J.) 20090101 |
Advances in pharmacological strategies for the prevention of cataract development. | Indian journal of ophthalmology 20090101 |
Transcriptomic and metabolic responses of Staphylococcus aureus exposed to supra-physiological temperatures. | BMC microbiology 20090101 |
Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation. | BMC psychiatry 20090101 |
Hypoxia. Hypoxia, hypoxia inducible factor and myeloid cell function. | Arthritis research & therapy 20090101 |
Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources. | PloS one 20090101 |
Expression profiling of genes involved in collagen turnover in tendons from cerebral palsy patients. | Connective tissue research 20090101 |
Proteomic and network analysis characterize stage-specific metabolism in Trypanosoma cruzi. | BMC systems biology 20090101 |
Effect of a glucose impulse on the CcpA regulon in Staphylococcus aureus. | BMC microbiology 20090101 |
Proteomics of Porphyromonas gingivalis within a model oral microbial community. | BMC microbiology 20090101 |
Hypoxia. Hypoxia in the pathogenesis of systemic sclerosis. | Arthritis research & therapy 20090101 |
Genomic characterization of methanomicrobiales reveals three classes of methanogens. | PloS one 20090101 |
Modeling heterocyst pattern formation in cyanobacteria. | BMC bioinformatics 20090101 |
A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability. | Molecular systems biology 20090101 |
Activity and gene expression profile of certain antioxidant enzymes in different organs of rats after subacute cyanide exposure: effect of alpha-ketoglutarate. | Drug and chemical toxicology 20090101 |
Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea. | Genome biology 20090101 |
Glucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells. | PloS one 20090101 |
Synergistic effect of imp/ostA and msbA in hydrophobic drug resistance of Helicobacter pylori. | BMC microbiology 20090101 |
Exploiting gene deletion fitness effects in yeast to understand the modular architecture of protein complexes under different growth conditions. | BMC systems biology 20090101 |
Genome-wide analysis of the RpoN regulon in Geobacter sulfurreducens. | BMC genomics 20090101 |
Expression of genes involved in nitrogen assimilation and the C/N balance sensing in Prochlorococcus sp. strain SS120. | Gene expression 20090101 |
Adherence to the Mediterranean diet moderates the association of aminotransferases with the prevalence of the metabolic syndrome; the ATTICA study. | Nutrition & metabolism 20090101 |
Development and experimental verification of a genome-scale metabolic model for Corynebacterium glutamicum. | Microbial cell factories 20090101 |
Expression of prolyl 3-hydroxylase genes in embryonic and adult mouse tissues. | Cell structure and function 20090101 |
Brucella microti: the genome sequence of an emerging pathogen. | BMC genomics 20090101 |
Comparative genomics in chicken and Pekin duck using FISH mapping and microarray analysis. | BMC genomics 20090101 |
Genome-scale gene/reaction essentiality and synthetic lethality analysis. | Molecular systems biology 20090101 |
Metabolomics-driven quantitative analysis of ammonia assimilation in E. coli. | Molecular systems biology 20090101 |
Potentials and limitations of microorganisms as renal failure biotherapeutics. | Biologics : targets & therapy 20090101 |
Synthesis of hydrazones derivatives of quinoxalinone--prospective antimicrobial and antiinflammatory agents. | Acta poloniae pharmaceutica 20090101 |
Pathway analysis for intracellular Porphyromonas gingivalis using a strain ATCC 33277 specific database. | BMC microbiology 20090101 |
Nutrition controls mitochondrial biogenesis in the Drosophila adipose tissue through Delg and cyclin D/Cdk4. | PloS one 20090101 |
Determination of enzymatic source of alanine aminotransferase activity in serum from dogs with liver injury. | Journal of pharmacological and toxicological methods 20090101 |
Time-resolved transcriptome analysis of Bacillus subtilis responding to valine, glutamate, and glutamine. | PloS one 20090101 |
Genome-scale comparison and constraint-based metabolic reconstruction of the facultative anaerobic Fe(III)-reducer Rhodoferax ferrireducens. | BMC genomics 20090101 |
LKR/SDH plays important roles throughout the tick life cycle including a long starvation period. | PloS one 20090101 |
Metabolic fluxes in the central carbon metabolism of Dinoroseobacter shibae and Phaeobacter gallaeciensis, two members of the marine Roseobacter clade. | BMC microbiology 20090101 |
Mitigation of mitochondrial dysfunction and regulation of eNOS expression during experimental myocardial necrosis by alpha-mangostin, a xanthonic derivative from Garcinia mangostana. | Drug and chemical toxicology 20090101 |
An ATP and oxalate generating variant tricarboxylic acid cycle counters aluminum toxicity in Pseudomonas fluorescens. | PloS one 20090101 |
The amidase domain of lipoamidase specifically inactivates lipoylated proteins in vivo. | PloS one 20090101 |
Involvement of an alternatively spliced mitochondrial oxodicarboxylate carrier in adipogenesis in 3T3-L1 cells. | Journal of biomedical science 20090101 |
Tumor suppressor function of Syk in human MCF10A in vitro and normal mouse mammary epithelium in vivo. | PloS one 20090101 |
Anaesthetic management of an adult patient with DOOR syndrome: a case report. | Cases journal 20090101 |
Identification of novel androgen-responsive genes by sequencing of LongSAGE libraries. | BMC genomics 20090101 |
Transcription analysis of central metabolism genes in Escherichia coli. Possible roles of sigma38 in their expression, as a response to carbon limitation. | PloS one 20090101 |
Sigma factors for cyanobacterial transcription. | Gene regulation and systems biology 20090101 |
An insight into the role of phosphotransacetylase (pta) and the acetate/acetyl-CoA node in Escherichia coli. | Microbial cell factories 20090101 |
Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons. | BMC genomics 20090101 |
Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches. | PloS one 20090101 |
13C-metabolic flux ratio and novel carbon path analyses confirmed that Trichoderma reesei uses primarily the respirative pathway also on the preferred carbon source glucose. | BMC systems biology 20090101 |
Regulation of intestinal epithelial cells transcriptome by enteric glial cells: impact on intestinal epithelial barrier functions. | BMC genomics 20090101 |
Ribosome and transcript copy numbers, polysome occupancy and enzyme dynamics in Arabidopsis. | Molecular systems biology 20090101 |
An integrated analysis of molecular acclimation to high light in the marine diatom Phaeodactylum tricornutum. | PloS one 20090101 |
The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels. | PloS one 20090101 |
Mechanism of dinitrochlorobenzene-induced dermatitis in mice: role of specific antibodies in pathogenesis. | PloS one 20090101 |
Evolution by leaps: gene duplication in bacteria. | Biology direct 20090101 |
A genome-wide survey for host response of silkworm, Bombyx mori during pathogen Bacillus bombyseptieus infection. | PloS one 20090101 |
Coenzyme Q10 effects in neurodegenerative disease. | Neuropsychiatric disease and treatment 20090101 |
Effective identification of conserved pathways in biological networks using hidden Markov models. | PloS one 20090101 |
The hydrogenosomes of Psalteriomonas lanterna. | BMC evolutionary biology 20090101 |
The emerging role of cardiovascular risk factor-induced mitochondrial dysfunction in atherogenesis. | Journal of biomedical science 20090101 |
Proteome analysis of Aspergillus niger: lactate added in starch-containing medium can increase production of the mycotoxin fumonisin B2 by modifying acetyl-CoA metabolism. | BMC microbiology 20090101 |
Extramitochondrial Ca2+ in the nanomolar range regulates glutamate-dependent oxidative phosphorylation on demand. | PloS one 20090101 |
Estradiol stimulates vasodilatory and metabolic pathways in cultured human endothelial cells. | PloS one 20090101 |
Folate nutrition is related to neuropsychological functions in the elderly. | Nutrition research and practice 20090101 |
Microarray analysis of retinal gene expression in Egr-1 knockout mice. | Molecular vision 20090101 |
Functional genomics of pH homeostasis in Corynebacterium glutamicum revealed novel links between pH response, oxidative stress, iron homeostasis and methionine synthesis. | BMC genomics 20090101 |
Proteomic analysis of regenerating mouse liver following 50% partial hepatectomy. | Proteome science 20090101 |
Tuning microbial hosts for membrane protein production. | Microbial cell factories 20090101 |
Transcriptional adaptations following exercise in thoroughbred horse skeletal muscle highlights molecular mechanisms that lead to muscle hypertrophy. | BMC genomics 20090101 |
Mechanisms of c-myc degradation by nickel compounds and hypoxia. | PloS one 20090101 |
Amino acids - Guidelines on Parenteral Nutrition, Chapter 4. | German medical science : GMS e-journal 20090101 |
Oxidative stress and antioxidant defenses in asthmatic murine model exposed to printer emissions and environmental tobacco smoke. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20090101 |
Effects of long-term oxygen treatment on alpha-ketoglutarate dehydrogenase activity and oxidative modifications in mitochondria of the guinea pig heart. | European journal of medical research 20090101 |
Defective glycinergic synaptic transmission in zebrafish motility mutants. | Frontiers in molecular neuroscience 20090101 |
Treatment advances in Alzheimer's disease based on the oxidative stress model. | F1000 medicine reports 20090101 |
Xylella fastidiosa gene expression analysis by DNA microarrays. | Genetics and molecular biology 20090101 |
Molecular cloning and function analysis of an anthocyanidin synthase gene from Ginkgo biloba, and its expression in abiotic stress responses. | Molecules and cells 20081231 |
Specificity and reactivity in menaquinone biosynthesis: the structure of Escherichia coli MenD (2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase). | Journal of molecular biology 20081231 |
Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha. | The Biochemical journal 20081215 |
1,25(OH)2D3 regulates collagen quality in an osteoblastic cell culture system. | Biochemical and biophysical research communications 20081212 |
Snapshots of catalysis in the E1 subunit of the pyruvate dehydrogenase multienzyme complex. | Structure (London, England : 1993) 20081212 |
Effect of alpha-ketoglutarate on monoclonal antibody production of hybridoma cell lines in serum-free and serum-containing medium. | Applied biochemistry and biotechnology 20081201 |
Metabolic cycling in control of glucose-stimulated insulin secretion. | American journal of physiology. Endocrinology and metabolism 20081201 |
Genome-scale model for Clostridium acetobutylicum: Part I. Metabolic network resolution and analysis. | Biotechnology and bioengineering 20081201 |
Coordination changes and auto-hydroxylation of FIH-1: uncoupled O2-activation in a human hypoxia sensor. | Journal of inorganic biochemistry 20081201 |
Inhibition of 2-oxoglutarate dehydrogenase in potato tuber suggests the enzyme is limiting for respiration and confirms its importance in nitrogen assimilation, | Plant physiology 20081201 |
Metabolome phenotyping of inorganic carbon limitation in cells of the wild type and photorespiratory mutants of the cyanobacterium Synechocystis sp. strain PCC 6803. | Plant physiology 20081201 |
Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo. | American journal of physiology. Heart and circulatory physiology 20081201 |
Arginine and nitrogen storage. | Current opinion in structural biology 20081201 |
Towards understanding the nitrogen signal transduction for nif gene expression in Klebsiella pneumoniae. | The FEBS journal 20081201 |
PII, the key regulator of nitrogen metabolism in the cyanobacteria. | Science in China. Series C, Life sciences 20081201 |
[Metabonomic profile of urine from rats administrated with different treatment period of rifampin]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20081201 |
Spatial distribution of cytosolic NADP(+)-isocitrate dehydrogenase in pine embryos and seedlings. | Tree physiology 20081201 |
A dialogue between the hypoxia-inducible factor and the tumor microenvironment. | Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201 |
Protective effect of aspartate and glutamate on cardiac mitochondrial function during myocardial infarction in experimental rats. | Chemico-biological interactions 20081125 |
Mutating the tight-dimer interface of dihydrodipicolinate synthase disrupts the enzyme quaternary structure: toward a monomeric enzyme. | Biochemistry 20081118 |
Alpha-ketoglutarate oxidoreductase, an essential salvage enzyme of energy metabolism, in coccoid form of Helicobacter pylori. | Biochemical and biophysical research communications 20081107 |
Isolation of a novel family of genes related to 2-oxoglutarate-dependent dioxygenases from soybean and analysis of their expression during root nodule senescence. | Journal of plant physiology 20081101 |
Crystal structure of DFA0005 complexed with alpha-ketoglutarate: a novel member of the ICL/PEPM superfamily from alkali-tolerant Deinococcus ficus. | Proteins 20081101 |
The impact of N-nitrosomelatonin as nitric oxide donor in cell culture experiments. | Journal of pineal research 20081101 |
Endurance exercise as a countermeasure for aging. | Diabetes 20081101 |
Complex I dysfunction redirects cellular and mitochondrial metabolism in Arabidopsis. | Plant physiology 20081101 |
Conservation of notochord gene expression across chordates: insights from the Leprecan gene family. | Genesis (New York, N.Y. : 2000) 20081101 |
Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation. | Journal of immunology (Baltimore, Md. : 1950) 20081101 |
Carbon source-dependent modulation of NADP-glutamate dehydrogenases in isophthalate-degrading Pseudomonas aeruginosa strain PP4, Pseudomonas strain PPD and Acinetobacter lwoffii strain ISP4. | Microbiology (Reading, England) 20081101 |
Ornithine delta-aminotransferase: An enzyme implicated in salt tolerance in higher plants. | Plant signaling & behavior 20081101 |
A stopped flow transient kinetic analysis of substrate binding and catalysis in Escherichia coli D-3-phosphoglycerate dehydrogenase. | The Journal of biological chemistry 20081031 |
Auto-hydroxylation of FIH-1: an Fe(ii), alpha-ketoglutarate-dependent human hypoxia sensor. | Chemical communications (Cambridge, England) 20081021 |
Metabolic pathways in Anopheles stephensi mitochondria. | The Biochemical journal 20081015 |
Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO. | FEBS letters 20081015 |
Novel roles for collagens in wiring the vertebrate nervous system. | Current opinion in cell biology 20081001 |
Impact of short- and medium-chain organic acids, acylcarnitines, and acyl-CoAs on mitochondrial energy metabolism. | Biochimica et biophysica acta 20081001 |
Biochemical and genetic characterization of Arabidopsis flavanone 3beta-hydroxylase. | Plant physiology and biochemistry : PPB 20081001 |
Identification of target genes for a MYB-type anthocyanin regulator in Gerbera hybrida. | Journal of experimental botany 20081001 |
Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart. | The FEBS journal 20081001 |
Insights from retinitis pigmentosa into the roles of isocitrate dehydrogenases in the Krebs cycle. | Nature genetics 20081001 |
Variation of metabolic profiles in developing maize kernels up- and down-regulated for the hda101 gene. | Journal of experimental botany 20081001 |
The long-term effect of alpha-ketoglutarate, given early in postnatal life, on both growth and various bone parameters in pigs. | Journal of animal physiology and animal nutrition 20081001 |
Creatine, arginine alpha-ketoglutarate, amino acids, and medium-chain triglycerides and endurance and performance. | International journal of sport nutrition and exercise metabolism 20081001 |
Toxicology. | Indian journal of pharmacology 20081001 |
New method for reducing the binding power of sweet white wines. | Journal of agricultural and food chemistry 20080924 |
Evidence that two enzyme-derived histidine ligands are sufficient for iron binding and catalysis by factor inhibiting HIF (FIH). | The Journal of biological chemistry 20080919 |
Analysis of selected carbonyl oxidation products in wine by liquid chromatography with diode array detection. | Analytica chimica acta 20080919 |
Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA. | The Journal of biological chemistry 20080905 |
Structural studies of Saccharomyces cerevesiae mitochondrial NADP-dependent isocitrate dehydrogenase in different enzymatic states reveal substantial conformational changes during the catalytic reaction. | Protein science : a publication of the Protein Society 20080901 |
Effects of thiamine and benfotiamine on intracellular glucose metabolism and relevance in the prevention of diabetic complications. | Acta diabetologica 20080901 |
Biochemical characterization of stage-specific isoforms of aspartate aminotransferases from Trypanosoma cruzi and Trypanosoma brucei. | Molecular and biochemical parasitology 20080901 |
Dynamic states of the DNA repair enzyme AlkB regulate product release. | EMBO reports 20080901 |
Ethylene production by metabolic engineering of the yeast Saccharomyces cerevisiae. | Metabolic engineering 20080901 |
Long-term effects of corticosterone on behavior, oxidative and energy metabolism of parietotemporal cerebral cortex and hippocampus of rats: comparison to intracerebroventricular streptozotocin. | Journal of neural transmission (Vienna, Austria : 1996) 20080901 |
Reduction of mitochondrial oxidative damage and improved mitochondrial efficiency by administration of crocetin against benzo[a]pyrene induced experimental animals. | Biological & pharmaceutical bulletin 20080901 |
Lipid lowering effect of antioxidant alpha-lipoic Acid in experimental atherosclerosis. | Journal of clinical biochemistry and nutrition 20080901 |
Purification and characteristics of functional properties of soluble nucleoside triphosphatase (apyrase) from bovine brain. | Biochemistry. Biokhimiia 20080901 |
alpha-Ketoglutarate biosynthesis in wild and industrial strains of Lactococcus lactis. | Letters in applied microbiology 20080901 |
All-atom replica exchange molecular simulation of protein BBL. | Proteins 20080815 |
Huperzine A attenuates mitochondrial dysfunction after middle cerebral artery occlusion in rats. | Journal of neuroscience research 20080815 |
Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle: II. Heterogeneity of metabolite labeling pattern. | The Journal of biological chemistry 20080808 |
Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle. I. Interrelation between gluconeogenesis and cataplerosis; formation of methoxamates from aminooxyacetate and ketoacids. | The Journal of biological chemistry 20080808 |
Stimuli-responsive polyguanidino-oxanorbornene membrane transporters as multicomponent sensors in complex matrices. | Journal of the American Chemical Society 20080806 |
Glutamate availability is important in intramuscular amino acid metabolism and TCA cycle intermediates but does not affect peak oxidative metabolism. | Journal of applied physiology (Bethesda, Md. : 1985) 20080801 |
Immobilization-stabilization of a new recombinant glutamate dehydrogenase from Thermus thermophilus. | Applied microbiology and biotechnology 20080801 |
Difference in metabolite levels between photoautotrophic and photomixotrophic cultures of Synechocystis sp. PCC 6803 examined by capillary electrophoresis electrospray ionization mass spectrometry. | Journal of experimental botany 20080801 |
Glutamate export at the choroid plexus in health, thiamin deficiency, and ethanol intoxication: review and hypothesis. | Alcoholism, clinical and experimental research 20080801 |
Substrate specificity and structure of human aminoadipate aminotransferase/kynurenine aminotransferase II. | Bioscience reports 20080801 |
The role of oxidative stress in the development of congestive heart failure in a chicken genotype selected for rapid growth. | Avian pathology : journal of the W.V.P.A 20080801 |
Beta-cell alpha-ketoglutarate hydroxylases may acutely participate in insulin secretion. | Metabolism: clinical and experimental 20080801 |
Interaction of the signal transduction protein GlnJ with the cellular targets AmtB1, GlnE and GlnD in Rhodospirillum rubrum: dependence on manganese, 2-oxoglutarate and the ADP/ATP ratio. | Microbiology (Reading, England) 20080801 |
Inactivation of the general transcription factor TnrA in Bacillus subtilis by proteolysis. | Microbiology (Reading, England) 20080801 |
Identification and functional analysis of light-responsive unique genes and gene family members in rice. | PLoS genetics 20080801 |
Biological effects of 2-oxoglutarate with particular emphasis on the regulation of protein, mineral and lipid absorption/metabolism, muscle performance, kidney function, bone formation and cancerogenesis, all viewed from a healthy ageing perspective state of the art--review article. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801 |
Muscle contraction and force: the importance of an ancillary network, nutrient supply and waste removal. | International journal of molecular sciences 20080801 |
Quantifying reductive carboxylation flux of glutamine to lipid in a brown adipocyte cell line. | The Journal of biological chemistry 20080725 |
Evolution of quaternary structure in a homotetrameric enzyme. | Journal of molecular biology 20080718 |
Characterization of recombinant human prolyl 3-hydroxylase isoenzyme 2, an enzyme modifying the basement membrane collagen IV. | The Journal of biological chemistry 20080711 |
Polyhydroxyalkanoate production from whey by Pseudomonas hydrogenovora. | Bioresource technology 20080701 |
High doses of nicotinamide prevent oxidative mitochondrial dysfunction in a cellular model and improve motor deficit in a Drosophila model of Parkinson's disease. | Journal of neuroscience research 20080701 |
Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. | Molecular & cellular proteomics : MCP 20080701 |
Baicalein induces functional hypoxia-inducible factor-1alpha and angiogenesis. | Molecular pharmacology 20080701 |
Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria. | Molecular microbiology 20080701 |
Sugar signalling mediates cluster root formation and phosphorus starvation-induced gene expression in white lupin. | Journal of experimental botany 20080701 |
Identification and transcriptional profiling of Pseudomonas putida genes involved in furoic acid metabolism. | FEMS microbiology letters 20080701 |
Detection and identification of novel metabolomic biomarkers in preeclampsia. | Reproductive sciences (Thousand Oaks, Calif.) 20080701 |
Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae. | Biochemistry 20080701 |
An oxygen molecular sensor, the HIF prolyl 4-hydroxylase, in the marine protist Perkinsus olseni. | Protist 20080701 |
A candidate gene survey of quantitative trait loci affecting chemical composition in tomato fruit. | Journal of experimental botany 20080701 |
Natural product juglone targets three key enzymes from Helicobacter pylori: inhibition assay with crystal structure characterization. | Acta pharmacologica Sinica 20080701 |
Metabolic profiling of an Echinostoma caproni infection in the mouse for biomarker discovery. | PLoS neglected tropical diseases 20080701 |
Inactivation of spkD, encoding a Ser/Thr kinase, affects the pool of the TCA cycle metabolites in Synechocystis sp. strain PCC 6803. | Microbiology (Reading, England) 20080701 |
An SOD mimic protects NADP+-dependent isocitrate dehydrogenase against oxidative inactivation. | Free radical research 20080701 |
Truncation of the krebs cycle during hypoglycemic coma. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20080701 |
A Zn-surprise in Ehlers-Danlos syndrome. | Matrix biology : journal of the International Society for Matrix Biology 20080701 |
[Enhancing alpha-ketoglutaric acid production in Torulopsis glabrata: increase of acetyl-CoA availability]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20080701 |
Effect of poly(D, L-lactic acid) nanoparticles as triptolide carrier on abating rats renal toxicity by NMR-based metabolic analysis. | Journal of nanoscience and nanotechnology 20080701 |
PDK-1 regulates lactate production in hypoxia and is associated with poor prognosis in head and neck squamous cancer. | British journal of cancer 20080617 |
Regulation of hypoxia-inducible factor-1alpha by NF-kappaB. | The Biochemical journal 20080615 |
Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases. | Neuroscience 20080602 |
Arabidopsis DMR6 encodes a putative 2OG-Fe(II) oxygenase that is defense-associated but required for susceptibility to downy mildew. | The Plant journal : for cell and molecular biology 20080601 |
Structural bases for the specific interactions between the E2 and E3 components of the Thermus thermophilus 2-oxo acid dehydrogenase complexes. | Journal of biochemistry 20080601 |
Mitochondrial respiratory pathways modulate nitrate sensing and nitrogen-dependent regulation of plant architecture in Nicotiana sylvestris. | The Plant journal : for cell and molecular biology 20080601 |
Hepatic mitochondrial transport of glutathione: studies in isolated rat liver mitochondria and H4IIE rat hepatoma cells. | Archives of biochemistry and biophysics 20080601 |
Dimethyl amiloride improves glucose homeostasis in mouse models of type 2 diabetes. | American journal of physiology. Endocrinology and metabolism 20080601 |
Anaplerosis from glucose, alpha-ketoisocaproate, and pyruvate in pancreatic islets, INS-1 cells and liver mitochondria. | Molecular and cellular biochemistry 20080601 |
Improvement of poly(gamma-glutamic acid) biosynthesis and redistribution of metabolic flux with the presence of different additives in Bacillus subtilis CGMCC 0833. | Applied microbiology and biotechnology 20080601 |
Gamma-hydroxybutyrate accumulation in Arabidopsis and tobacco plants is a general response to abiotic stress: putative regulation by redox balance and glyoxylate reductase isoforms. | Journal of experimental botany 20080601 |
Concerted modulation of alanine and glutamate metabolism in young Medicago truncatula seedlings under hypoxic stress. | Journal of experimental botany 20080601 |
Specialization of the paralogue LYS21 determines lysine biosynthesis under respiratory metabolism in Saccharomyces cerevisiae. | Microbiology (Reading, England) 20080601 |
Insights into the structural basis of substrate recognition by histidinol-phosphate aminotransferase from Corynebacterium glutamicum. | Acta crystallographica. Section D, Biological crystallography 20080601 |
Degradation of pyrimidines in Saccharomyces kluyveri: transamination of beta-alanine. | Nucleosides, nucleotides & nucleic acids 20080601 |
[Global expression profiling of Saccharomyces cerevisiae: metabolic remodeling in post-log phase]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080601 |
Changes in ECG and enzyme activity in rat heart after myocardial infarction: effect of TPP and MnCl2. | Journal of physiology and biochemistry 20080601 |
Structural insight into substrate binding and catalysis of a novel 2-keto-3-deoxy-D-arabinonate dehydratase illustrates common mechanistic features of the FAH superfamily. | Journal of molecular biology 20080530 |
Effect of mangiferin on benzo(a)pyrene induced lung carcinogenesis in experimental Swiss albino mice. | Natural product research 20080520 |
Does inhibition of degradation of hypoxia-inducible factor (HIF) alpha always lead to activation of HIF? Lessons learnt from the effect of proteasomal inhibition on HIF activity. | Journal of cellular biochemistry 20080515 |
Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae. | Biochemistry 20080513 |
Structure-function relationships in the 2-oxo acid dehydrogenase family: substrate-specific signatures and functional predictions for the 2-oxoglutarate dehydrogenase-like proteins. | Proteins 20080501 |
Remote renal preconditioning-induced cardioprotection: a key role of hypoxia inducible factor-prolyl 4-hydroxylases. | Molecular and cellular biochemistry 20080501 |
2-Oxoglutarate-dependent oxygenases control hepcidin gene expression. | Journal of hepatology 20080501 |
Metabolite profiling reveals distinct changes in carbon and nitrogen metabolism in phosphate-deficient barley plants (Hordeum vulgare L.). | Plant & cell physiology 20080501 |
The human side of hypoxia-inducible factor. | British journal of haematology 20080501 |
Structure-function studies of glutamate synthases: a class of self-regulated iron-sulfur flavoenzymes essential for nitrogen assimilation. | IUBMB life 20080501 |
(-)Epigallocatechin-gallate (EGCG) prevents mitochondrial damage in isoproterenol-induced cardiac toxicity in albino Wistar rats: a transmission electron microscopic and in vitro study. | Pharmacological research 20080501 |
Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. | PLoS genetics 20080501 |
Transcriptional Regulation of SDHa flavoprotein by nuclear respiratory factor-1 prevents pseudo-hypoxia in aerobic cardiac cells. | The Journal of biological chemistry 20080418 |
Kinetics and mechanism of degradation of p-chloronitrobenzene in water by ozonation. | Journal of hazardous materials 20080415 |
Cell free expression and functional reconstitution of eukaryotic drug transporters. | Biochemistry 20080415 |
Alterations of flavonoid biosynthesis in young grapevine (Vitis vinifera L.) leaves, flowers, and berries induced by the dioxygenase inhibitor prohexadione-Ca. | Journal of agricultural and food chemistry 20080409 |
Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease. | Biochimica et biophysica acta 20080401 |
Apparent negative co-operativity and substrate inhibition in overexpressed glutamate dehydrogenase from Escherichia coli. | FEMS microbiology letters 20080401 |
Metabolomics reveals unique and shared metabolic changes in response to heat shock, freezing and desiccation in the Antarctic midge, Belgica antarctica. | Journal of insect physiology 20080401 |
The absorption, tissue distribution and excretion of enteraly administered alpha-ketoglutarate in rats. | Journal of animal physiology and animal nutrition 20080401 |
Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines. | The American journal of pathology 20080401 |
Modification of respiratory-chain enzyme activities in brown adipose tissue mitochondria by idebenone (hydroxydecyl-ubiquinone). | Journal of bioenergetics and biomembranes 20080401 |
Different responses of the GlnB and GlnZ proteins upon in vitro uridylylation by the Azospirillum brasilense GlnD protein. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20080401 |
Predicting co-complexed protein pairs from heterogeneous data. | PLoS computational biology 20080401 |
Structural-dynamical properties of the transmembrane segment VI of the mitochondrial oxoglutarate carrier studied by site directed spin-labeling. | Molecular membrane biology 20080401 |
Robustness in Escherichia coli glutamate and glutamine synthesis studied by a kinetic model. | Journal of biological physics 20080401 |
Metabonomic study on the toxicity of Hei-Shun-Pian, the processed lateral root of Aconitum carmichaelii Debx. (Ranunculaceae). | Journal of ethnopharmacology 20080328 |
Comparative quantum mechanics/molecular mechanics (QM/MM) and density functional theory calculations on the oxo-iron species of taurine/alpha-ketoglutarate dioxygenase. | The journal of physical chemistry. A 20080320 |
Use of Lactobacillus plantarum fermentation products in bread-making to prevent Bacillus subtilis ropy spoilage. | International journal of food microbiology 20080320 |
Molecular identification of three Arabidopsis thaliana mitochondrial dicarboxylate carrier isoforms: organ distribution, bacterial expression, reconstitution into liposomes and functional characterization. | The Biochemical journal 20080315 |
Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors. | Bioorganic & medicinal chemistry letters 20080315 |
An inner membrane dioxygenase that generates the 2-hydroxymyristate moiety of Salmonella lipid A. | Biochemistry 20080304 |
Zinc toxicity alters mitochondrial metabolism and leads to decreased ATP production in hepatocytes. | Journal of applied toxicology : JAT 20080301 |
Preventing cell death induced by carbonyl stress, oxidative stress or mitochondrial toxins with vitamin B anti-AGE agents. | Molecular nutrition & food research 20080301 |
Profiling of external metabolites during production of hantavirus nucleocapsid protein with recombinant Saccharomyces cerevisiae. | Biotechnology letters 20080301 |
Proteasomal activity in placentas from women with preeclampsia and intrauterine growth restriction: implications for expression of HIF-alpha proteins. | Placenta 20080301 |
Expanding chemical biology of 2-oxoglutarate oxygenases. | Nature chemical biology 20080301 |
Metabolism of halophilic archaea. | Extremophiles : life under extreme conditions 20080301 |
Genetic networks of liver metabolism revealed by integration of metabolic and transcriptional profiling. | PLoS genetics 20080301 |
A Mouse Model of Metabolic Syndrome; Increase in Visceral Adipose Tissue Precedes the Development of Fatty Liver and Insulin Resistance in High-Fat Diet-Fed Male KK/Ta Mice. | Journal of clinical biochemistry and nutrition 20080301 |
Bofutsushosan, an Oriental Herbal Medicine, Attenuates the Weight Gain of White Adipose Tissue and the Increased Size of Adipocytes Associated with the Increase in Their Expression of Uncoupling Protein 1 in High-Fat Diet-Fed Male KK/Ta mice. | Journal of clinical biochemistry and nutrition 20080301 |
Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases. | The Journal of biological chemistry 20080215 |
1H NMR-based metabonomic analysis of urine from young spontaneously hypertensive rats. | Journal of pharmaceutical and biomedical analysis 20080213 |
Off-pathway, oxygen-dependent thiamine radical in the Krebs cycle. | Journal of the American Chemical Society 20080206 |
Dual role for a bacteriophytochrome in the bioenergetic control of Rhodopseudomonas palustris: enhancement of photosystem synthesis and limitation of respiration. | Biochimica et biophysica acta 20080201 |
Mitochondrial dysfunction is responsible for the intestinal calcium absorption inhibition induced by menadione. | Biochimica et biophysica acta 20080201 |
Year in review in Intensive Care Medicine, 2007. I. Experimental studies. Clinical studies: brain injury and neurology, renal failure and endocrinology. | Intensive care medicine 20080201 |
Computational and experimental analysis of redundancy in the central metabolism of Geobacter sulfurreducens. | PLoS computational biology 20080201 |
Organic acid concentrations in amniotic fluid found in normal and Down syndrome pregnancies. | Fetal diagnosis and therapy 20080201 |
Characterization of flavone synthase I from rice. | BMB reports 20080131 |
High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates. | The Biochemical journal 20080115 |
The role of loop and beta-turn residues as structural and functional determinants for the lipoyl domain from the Escherichia coli 2-oxoglutarate dehydrogenase complex. | The Biochemical journal 20080115 |
Endotoxin challenge reduces aconitase activity in myocardial tissue. | Archives of biochemistry and biophysics 20080115 |
Reversible inhibition of alpha-ketoglutarate dehydrogenase by hydrogen peroxide: glutathionylation and protection of lipoic acid. | Biochemistry 20080108 |
Development of a convenient peptide-based assay for lysyl hydroxylase. | Biopolymers 20080101 |
Elucidation of active site residues of Arabidopsis thaliana flavonol synthase provides a molecular platform for engineering flavonols. | Phytochemistry 20080101 |
Formation of diacetyl and acetoin by Lactococcus lactis via aspartate catabolism. | Journal of applied microbiology 20080101 |
Fuel-induced amplification of insulin secretion in mouse pancreatic islets exposed to a high sulfonylurea concentration: role of the NADPH/NADP+ ratio. | Diabetologia 20080101 |
Prolyl 4-hydroxylase activity-responsive transcription factors: from hydroxylation to gene expression and neuroprotection. | Frontiers in bioscience : a journal and virtual library 20080101 |
Biochemical factors limiting myocardial energy in a chicken genotype selected for rapid growth. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20080101 |
Stabilization of pulmonary mitochondrial enzyme system by capsaicin during benzo(a)pyrene induced experimental lung cancer. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080101 |
Alpha-ketoglutarate and N-acetyl cysteine protect PC12 cells from cyanide-induced cytotoxicity and altered energy metabolism. | Neurotoxicology 20080101 |
In vitro and in vivo evaluation of various carbonyl compounds against cyanide toxicity with particular reference to alpha-ketoglutaric acid. | Drug and chemical toxicology 20080101 |
Genetic evidence for a mitochondriate ancestry in the 'amitochondriate' flagellate Trimastix pyriformis. | PloS one 20080101 |
A model for carbohydrate metabolism in the diatom Phaeodactylum tricornutum deduced from comparative whole genome analysis. | PloS one 20080101 |
Genomic, genetic and structural analysis of pyoverdine-mediated iron acquisition in the plant growth-promoting bacterium Pseudomonas fluorescens SBW25. | BMC microbiology 20080101 |
Quantitative 1H NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures. | BMC plant biology 20080101 |
Comparison of metabolic flux distributions for MDCK cell growth in glutamine- and pyruvate-containing media. | Biotechnology progress 20080101 |
The implausibility of metabolic cycles on the prebiotic Earth. | PLoS biology 20080101 |
Primary biliary cirrhosis. | Orphanet journal of rare diseases 20080101 |
Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity. | BMC molecular biology 20080101 |
Attenuation of Biochemical Parameters in Streptozotocin-induced Diabetic Rats by Oral Administration of Extracts and Fractions of Cephalotaxus sinensis. | Journal of clinical biochemistry and nutrition 20080101 |
Mitochondrial lactate dehydrogenase is involved in oxidative-energy metabolism in human astrocytoma cells (CCF-STTG1). | PloS one 20080101 |
Striatal proteomic analysis suggests that first L-dopa dose equates to chronic exposure. | PloS one 20080101 |
MAO-B elevation in mouse brain astrocytes results in Parkinson's pathology. | PloS one 20080101 |
Changes in enzyme activities at the pyruvate node in glutamate-overproducing Corynebacterium glutamicum. | Journal of bioscience and bioengineering 20080101 |
NAD(H)-dependent glutamate dehydrogenase is essential for the survival of Arabidopsis thaliana during dark-induced carbon starvation. | Journal of experimental botany 20080101 |
Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice. | PloS one 20080101 |
Characterization of human mesenchymal stem cell secretome at early steps of adipocyte and osteoblast differentiation. | BMC molecular biology 20080101 |
Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia. | BMC microbiology 20080101 |
Association analysis of the FTO gene with obesity in children of Caucasian and African ancestry reveals a common tagging SNP. | PloS one 20080101 |
24-hour rhythms in oxidative stress during hepatocarcinogenesis in rats: effect of melatonin or alpha-ketoglutarate. | Redox report : communications in free radical research 20080101 |
The assembly of the plasmodial PLP synthase complex follows a defined course. | PloS one 20080101 |
Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major. | Molecular systems biology 20080101 |
Transcription of hexose transporters of Saccharomyces cerevisiae is affected by change in oxygen provision. | BMC microbiology 20080101 |
Increase in the contribution of transamination to the respiration of mitochondria during arousal. | Cryo letters 20080101 |
A yeast three-hybrid system that reconstitutes mammalian hypoxia inducible factor regulatory machinery. | BMC cell biology 20080101 |
Malate metabolism in Hoya carnosa mitochondria and its role in photosynthesis during CAM phase III. | Journal of experimental botany 20080101 |
Novel Anticancer Platinum(IV) Complexes with Adamantylamine: Their Efficiency and Innovative Chemotherapy Strategies Modifying Lipid Metabolism. | Metal-based drugs 20080101 |
Dietary alpha-ketoglutarate reduces gastrectomy-evoked loss of calvaria and trabecular bone in female rats. | Scandinavian journal of gastroenterology 20080101 |
Assessment of CcpA-mediated catabolite control of gene expression in Bacillus cereus ATCC 14579. | BMC microbiology 20080101 |
Studies with leucine, beta-hydroxybutyrate and ATP citrate lyase-deficient beta cells support the acetoacetate pathway of insulin secretion. | Biochimica et biophysica acta 20080101 |
Regulation of osmoadaptation in the moderate halophile Halobacillus halophilus: chloride, glutamate and switching osmolyte strategies. | Saline systems 20080101 |
Simultaneous gene expression profiling in human macrophages infected with Leishmania major parasites using SAGE. | BMC genomics 20080101 |
Expression of Brugmansia candida Hyoscyamine 6beta-Hydroxylase gene in Saccharomyces cerevisiae and its potential use as biocatalyst. | Microbial cell factories 20080101 |
Divergence of canonical danger signals: the genome-level expression patterns of human mononuclear cells subjected to heat shock or lipopolysaccharide. | BMC immunology 20080101 |
Formate hydrogenlyase in the hyperthermophilic archaeon, Thermococcus litoralis. | BMC microbiology 20080101 |
Yeast mitochondrial biogenesis: a role for the PUF RNA-binding protein Puf3p in mRNA localization. | PloS one 20080101 |
The hidden universal distribution of amino acid biosynthetic networks: a genomic perspective on their origins and evolution. | Genome biology 20080101 |
[Pharmacological significance of alpha lipoic acid in up to date treatment of diabetic neuropathy]. | Medicinski arhiv 20080101 |
Benfotiamine, a synthetic S-acyl thiamine derivative, has different mechanisms of action and a different pharmacological profile than lipid-soluble thiamine disulfide derivatives. | BMC pharmacology 20080101 |
Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins. | BMC genomics 20080101 |
Early vertebrate chromosome duplications and the evolution of the neuropeptide Y receptor gene regions. | BMC evolutionary biology 20080101 |
Nitrogen metabolism in haloarchaea. | Saline systems 20080101 |
Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk. | BMC medical genetics 20080101 |
A novel strategy involved in [corrected] anti-oxidative defense: the conversion of NADH into NADPH by a metabolic network. | PloS one 20080101 |
Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways. | Journal of biomedicine & biotechnology 20080101 |
Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study. | PloS one 20080101 |
[The role of the functional state of kidney mitochondria in predisposition of hydronephrotic rabits to gentamicin nephrotoxicity]. | Eksperimental'naia i klinicheskaia farmakologiia 20080101 |
Lipoic acid as an anti-inflammatory and neuroprotective treatment for Alzheimer's disease. | Advanced drug delivery reviews 20080101 |
Yeast cell factories for fine chemical and API production. | Microbial cell factories 20080101 |
Altered gene expression in highly purified enterocytes from patients with active coeliac disease. | BMC genomics 20080101 |
Complete genome of Phenylobacterium zucineum--a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562. | BMC genomics 20080101 |
Gene expression and functional studies of the optic nerve head astrocyte transcriptome from normal African Americans and Caucasian Americans donors. | PloS one 20080101 |
Adenine nucleotide translocator transports haem precursors into mitochondria. | PloS one 20080101 |
Global self-organization of the cellular metabolic structure. | PloS one 20080101 |
An extension of the coevolution theory of the origin of the genetic code. | Biology direct 20080101 |
Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia. | BMC genomics 20080101 |
'Fat mass and obesity associated' gene (FTO): no significant association of variant rs9939609 with weight loss in a lifestyle intervention and lipid metabolism markers in German obese children and adolescents. | BMC medical genetics 20080101 |
Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover. | Molecular cancer 20080101 |
Simplivariate models: ideas and first examples. | PloS one 20080101 |
Iterative reconstruction of a global metabolic model of Acinetobacter baylyi ADP1 using high-throughput growth phenotype and gene essentiality data. | BMC systems biology 20080101 |
A construct with fluorescent indicators for conditional expression of miRNA. | BMC biotechnology 20080101 |
Systemic multicompartmental effects of the gut microbiome on mouse metabolic phenotypes. | Molecular systems biology 20080101 |
Targeting aspartate aminotransferase in breast cancer. | Breast cancer research : BCR 20080101 |
Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes. | Molecular cancer 20080101 |
Glucose uptake and its effect on gene expression in prochlorococcus. | PloS one 20080101 |
Co-regulation analysis of closely linked genes identifies a highly recurrent gain on chromosome 17q25.3 in prostate cancer. | BMC cancer 20080101 |
The transcriptomic signature of fasting murine liver. | BMC genomics 20080101 |
A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans. | Genome biology 20080101 |
Active transport of glutamate in Leishmania (Leishmania) amazonensis. | The Journal of eukaryotic microbiology 20080101 |
The integrated analysis of metabolic and protein interaction networks reveals novel molecular organizing principles. | BMC systems biology 20080101 |
Growth of Yersinia pseudotuberculosis in human plasma: impacts on virulence and metabolic gene expression. | BMC microbiology 20080101 |
Comparative genomic analysis of carbon and nitrogen assimilation mechanisms in three indigenous bioleaching bacteria: predictions and validations. | BMC genomics 20080101 |
Comparative genomics of vesicomyid clam (Bivalvia: Mollusca) chemosynthetic symbionts. | BMC genomics 20080101 |
Multivariate gene expression analysis reveals functional connectivity changes between normal/tumoral prostates. | BMC systems biology 20080101 |
Dietary supplementation with phytohemagglutinin in combination with alpha-ketoglutarate limits the excretion of nitrogen via urinary tract. | Annals of agricultural and environmental medicine : AAEM 20080101 |
Response of the cytoplasmic and membrane proteome of Corynebacterium glutamicum ATCC 13032 to pH changes. | BMC microbiology 20080101 |
Comparative analysis of fatty acid desaturases in cyanobacterial genomes. | Comparative and functional genomics 20080101 |
Metabolic pathway alignment between species using a comprehensive and flexible similarity measure. | BMC systems biology 20080101 |
Prolyl 4-hydroxylases, key enzymes in the synthesis of collagens and regulation of the response to hypoxia, and their roles as treatment targets. | Annals of medicine 20080101 |
Three-dimensional culture for monoclonal antibody production by hybridoma cells immobilized in macroporous gel particles. | Biotechnology progress 20080101 |
[Transamination in the mechanism of protection of mitochondria from Ca2+ overload]. | Biomeditsinskaia khimiia 20080101 |
NAD-Malic Enzyme Affects Nitrogen Fixing Activity of Bradyrhizobium japonicum USDA 110 Bacteroids in Soybean Nodules. | Microbes and environments 20080101 |
Pyruvate-sensitive AOX exists as a non-covalently associated dimer in the homeothermic spadix of the skunk cabbage, Symplocarpus renifolius. | FEBS letters 20071222 |
The active site of an algal prolyl 4-hydroxylase has a large structural plasticity. | The Journal of biological chemistry 20071221 |
Succinate inhibition of alpha-ketoglutarate-dependent enzymes in a yeast model of paraganglioma. | Human molecular genetics 20071215 |
Crystal structure of the non-heme iron dioxygenase PtlH in pentalenolactone biosynthesis. | The Journal of biological chemistry 20071214 |
NifI inhibits nitrogenase by competing with Fe protein for binding to the MoFe protein. | Biochemical and biophysical research communications 20071214 |
New methodology for removing carbonyl compounds from sweet wines. | Journal of agricultural and food chemistry 20071212 |
Enantiomers of 4-amino-3-fluorobutanoic acid as substrates for gamma-aminobutyric acid aminotransferase. Conformational probes for GABA binding. | Biochemistry 20071204 |
Enhanced [3H] glutamate binding in the cerebellum of insulin-induced hypoglycaemic and streptozotocin-induced diabetic rats. | Cellular and molecular neurobiology 20071201 |
Control of key metabolic intersections in Bacillus subtilis. | Nature reviews. Microbiology 20071201 |
Enzyme substrate recognition in oxygen sensing: how the HIF trap snaps. | The Biochemical journal 20071201 |
DOOR syndrome: clinical report, literature review and discussion of natural history. | American journal of medical genetics. Part A 20071201 |
Ternary complex formation between AmtB, GlnZ and the nitrogenase regulatory enzyme DraG reveals a novel facet of nitrogen regulation in bacteria. | Molecular microbiology 20071201 |
Harnessing hypoxic adaptation to prevent, treat, and repair stroke. | Journal of molecular medicine (Berlin, Germany) 20071201 |
Genome-wide analysis of Rad52 foci reveals diverse mechanisms impacting recombination. | PLoS genetics 20071201 |
Integrated NMR-based metabonomic investigation of early metabolic effects of ethylene glycol monomethyl ether (EGME) on male reproductive organs in rats. | The Journal of toxicological sciences 20071201 |
[Metabonomics profile of urine from rats administrated with different treatment period of isoniazid]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20071201 |
Computational design of digital and memory biological devices. | Systems and synthetic biology 20071201 |
Structural characterization of the transmembrane segments of the mitochondrial oxoglutarate carrier (OGC) by NMR spectroscopy. | The Italian journal of biochemistry 20071201 |
Grape seed proanthocyanidins ameliorates isoproterenol-induced myocardial injury in rats by stabilizing mitochondrial and lysosomal enzymes: an in vivo study. | Life sciences 20071130 |
The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. | Science (New York, N.Y.) 20071130 |
Inhibitory properties of nerve-specific human glutamate dehydrogenase isozyme by chloroquine. | Journal of biochemistry and molecular biology 20071130 |
Preconditioning results in S-nitrosylation of proteins involved in regulation of mitochondrial energetics and calcium transport. | Circulation research 20071126 |
CD and MCD of CytC3 and taurine dioxygenase: role of the facial triad in alpha-KG-dependent oxygenases. | Journal of the American Chemical Society 20071121 |
Role of rat organic anion transporter 3 (Oat3) in the renal basolateral transport of glutathione. | Chemico-biological interactions 20071120 |
Mitochondrial transport proteins of the brain. | Journal of neuroscience research 20071115 |
The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin. | The EMBO journal 20071114 |
Escherichia coli PII signal transduction protein controlling nitrogen assimilation acts as a sensor of adenylate energy charge in vitro. | Biochemistry 20071113 |
Spectroscopic evidence for a high-spin Br-Fe(IV)-oxo intermediate in the alpha-ketoglutarate-dependent halogenase CytC3 from Streptomyces. | Journal of the American Chemical Society 20071107 |
Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae. | Biochemistry 20071106 |
The impact of PHB accumulation on L-glutamate production by recombinant Corynebacterium glutamicum. | Journal of biotechnology 20071101 |
Antimitochondrial antibodies in acute liver failure: implications for primary biliary cirrhosis. | Hepatology (Baltimore, Md.) 20071101 |
The impact of preoperative micronutrient supplementation in lung surgery. A prospective randomized trial of oral supplementation of combined alpha-ketoglutaric acid and 5-hydroxymethylfurfural. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20071101 |
Osteoma of the calvaria in L-2-hydroxyglutaric aciduria. | Journal of inherited metabolic disease 20071101 |
Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis. | Nature 20071101 |
Global gene expression profiling of wild type and lysC knockout Escherichia coli W3110. | FEMS microbiology letters 20071101 |
From endosymbiont to host-controlled organelle: the hijacking of mitochondrial protein synthesis and metabolism. | PLoS computational biology 20071101 |
Osmotically induced synthesis of the compatible solute hydroxyectoine is mediated by an evolutionarily conserved ectoine hydroxylase. | The Journal of biological chemistry 20071026 |
Hypoxia-inducible factor 1 (HIF-1) pathway. | Science's STKE : signal transduction knowledge environment 20071009 |
Stereospecific enzymatic transformation of alpha-ketoglutarate to (2S,3R)-3-methyl glutamate during acidic lipopeptide biosynthesis. | Journal of the American Chemical Society 20071003 |
Purification and characterization of the bifunctional uridylyltransferase and the signal transducing proteins GlnB and GlnK from Herbaspirillum seropedicae. | Protein expression and purification 20071001 |
Effects of ornithine alpha-ketoglutarate on protein metabolism in Yoshida sarcoma-bearing rats. | Clinical nutrition (Edinburgh, Scotland) 20071001 |
L-2-hydroxyglutaric aciduria, a defect of metabolite repair. | Journal of inherited metabolic disease 20071001 |
Effect of gamma-immunoglobulin on the asaccharolytic growth of Porphyromonas gingivalis. | Journal of periodontal research 20071001 |
Novel insights into L-2-hydroxyglutaric aciduria: mass isotopomer studies reveal 2-oxoglutaric acid as the metabolic precursor of L-2-hydroxyglutaric acid. | Journal of inherited metabolic disease 20071001 |
Biochemistry and bioenergetics of glutaryl-CoA dehydrogenase deficiency. | Journal of inherited metabolic disease 20071001 |
The differential effects of superoxide anion, hydrogen peroxide and hydroxyl radical on cardiac mitochondrial oxidative phosphorylation. | Free radical research 20071001 |
Alpha-ketoglutarate is the precursor of L-2-hydroxyglutarate. | Journal of inherited metabolic disease 20071001 |
Three 2-oxoacid dehydrogenase operons in Haloferax volcanii: expression, deletion mutants and evolution. | Microbiology (Reading, England) 20071001 |
Metabolic reconstruction and modeling of nitrogen fixation in Rhizobium etli. | PLoS computational biology 20071001 |
Chemoenzymatic synthesis of glutamic acid analogues: substrate specificity and synthetic applications of branched chain aminotransferase from Escherichia coli. | The Journal of organic chemistry 20070928 |
Menaquinone biosynthesis in Escherichia coli: identification of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate as a novel intermediate and re-evaluation of MenD activity. | Biochemistry 20070925 |
Structural and functional properties of isocitrate dehydrogenase from the psychrophilic bacterium Desulfotalea psychrophila reveal a cold-active enzyme with an unusual high thermal stability. | Journal of molecular biology 20070907 |
Purification of branched-chain amino acid aminotransferase from Helicobacter pylori NCTC 11637. | Amino acids 20070901 |
Glutamate production by Corynebacterium glutamicum: dependence on the oxoglutarate dehydrogenase inhibitor protein OdhI and protein kinase PknG. | Applied microbiology and biotechnology 20070901 |
Mitochondrial protein lipoylation does not exclusively depend on the mtKAS pathway of de novo fatty acid synthesis in Arabidopsis. | Plant physiology 20070901 |
Structural features of aluminium(III) complexes with bioligands in glutamate dehydrogenase reaction system--a review. | Journal of inorganic biochemistry 20070901 |
Structural and mechanistic basis of penicillin-binding protein inhibition by lactivicins. | Nature chemical biology 20070901 |
Ectopic expression of phosphoenolpyruvate carboxylase in Vicia narbonensis seeds: effects of improved nutrient status on seed maturation and transcriptional regulatory networks. | The Plant journal : for cell and molecular biology 20070901 |
Terrequinone A biosynthesis through L-tryptophan oxidation, dimerization and bisprenylation. | Nature chemical biology 20070901 |
Valproic acid metabolites inhibit dihydrolipoyl dehydrogenase activity leading to impaired 2-oxoglutarate-driven oxidative phosphorylation. | Biochimica et biophysica acta 20070901 |
Peripheral tolerance and the qualitative characteristics of autoreactive T cell clones in primary biliary cirrhosis. | Journal of immunology (Baltimore, Md. : 1950) 20070901 |
Offering surprises: TCA cycle regulation in Corynebacterium glutamicum. | Trends in microbiology 20070901 |
The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins. | Journal of structural and functional genomics 20070901 |
The daily timing of gene expression and physiology in mammals. | Dialogues in clinical neuroscience 20070901 |
Expression and sub-cellular localization of human ABH family molecules. | Journal of cellular and molecular medicine 20070901 |
Pathogenesis of Alzheimer's disease. | Clinical interventions in aging 20070901 |
Crystal structure and biochemical properties of the D-arabinose dehydrogenase from Sulfolobus solfataricus. | Journal of molecular biology 20070831 |
Zinc irreversibly damages major enzymes of energy production and antioxidant defense prior to mitochondrial permeability transition. | The Journal of biological chemistry 20070817 |
Succinate modulation of H2O2 release at NADH:ubiquinone oxidoreductase (Complex I) in brain mitochondria. | The Biochemical journal 20070815 |
Post-translational modifications of collagen upon BMP-induced osteoblast differentiation. | Biochemical and biophysical research communications 20070803 |
Expanding the lysyl hydroxylase toolbox: new insights into the localization and activities of lysyl hydroxylase 3 (LH3). | Journal of cellular physiology 20070801 |
Alpha-ketoglutarate stimulates procollagen production in cultured human dermal fibroblasts, and decreases UVB-induced wrinkle formation following topical application on the dorsal skin of hairless mice. | Biological & pharmaceutical bulletin 20070801 |
Mechanisms and kinetics of chelating reaction between novel chitosan derivatives and Zn(II). | Journal of hazardous materials 20070719 |
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity. | Nature 20070705 |
Preparation and properties of modified chitosan as potential matrix materials for drug sustained-release beads. | International journal of biological macromolecules 20070701 |
Cl- -dependent upregulation of human organic anion transporters: different effects on transport kinetics between hOAT1 and hOAT3. | American journal of physiology. Renal physiology 20070701 |
NAD-dependent isocitrate dehydrogenase mutants of Arabidopsis suggest the enzyme is not limiting for nitrogen assimilation. | Plant physiology 20070701 |
Replacement of non-heme Fe(II) with Cu(II) in the alpha-ketoglutarate dependent DNA repair enzyme AlkB: spectroscopic characterization of the active site. | Journal of inorganic biochemistry 20070701 |
Low intensity training decreases markers of oxidative stress in skeletal muscle of mdx mice. | Free radical biology & medicine 20070701 |
The road to non-heme oxoferryls and beyond. | Accounts of chemical research 20070701 |
Sequential measurement of aminotransferase activities by amperometric biosensors. | Biosensors & bioelectronics 20070615 |
Antioxidant properties of Krebs cycle intermediates against malonate pro-oxidant activity in vitro: a comparative study using the colorimetric method and HPLC analysis to determine malondialdehyde in rat brain homogenates. | Life sciences 20070613 |
Lysyl hydroxylase 2 is a specific telopeptide hydroxylase, while all three isoenzymes hydroxylate collagenous sequences. | Matrix biology : journal of the International Society for Matrix Biology 20070601 |
The metabolic role of isoleucine in detoxification of ammonia in cultured mouse neurons and astrocytes. | Neurochemistry international 20070601 |
Proteome and immunome of the venom of the Thai cobra, Naja kaouthia. | Toxicon : official journal of the International Society on Toxinology 20070601 |
Hypotonic swelling of salicylate-treated cochlear outer hair cells. | Hearing research 20070601 |
Functional and structural role of amino acid residues in the odd-numbered transmembrane alpha-helices of the bovine mitochondrial oxoglutarate carrier. | Journal of molecular biology 20070601 |
Responses of the mitochondrial alpha-ketoglutarate dehydrogenase complex to thiamine deficiency may contribute to regional selective vulnerability. | Neurochemistry international 20070601 |
Light-dependent assimilation of trans-cinnamate by Rhodobacter sphaeroides OU5. | Current microbiology 20070601 |
Protective effect of dietary squalene supplementation on mitochondrial function in liver of aged rats. | Prostaglandins, leukotrienes, and essential fatty acids 20070601 |
Gene expression profiles of Chlamydophila pneumoniae during the developmental cycle and iron depletion-mediated persistence. | PLoS pathogens 20070601 |
Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia. | The Yale journal of biology and medicine 20070601 |
Probing the iron-substrate orientation for taurine/alpha-ketoglutarate dioxygenase using deuterium electron spin echo envelope modulation spectroscopy. | Biochemistry 20070522 |
Characterization of a lipoate-protein ligase A gene of rice (Oryza sativa L.). | Gene 20070515 |
Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans. | Biochemistry 20070508 |
Enhanced transaminase activity of a bifunctional L-aspartate 4-decarboxylase. | Biochemical and biophysical research communications 20070504 |
Role of the H domain of the histidine kinase-like protein NifL in signal transmission. | The Journal of biological chemistry 20070504 |
Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex. | Journal of molecular biology 20070504 |
Recruitment of NADH shuttling in pressure-overloaded and hypertrophic rat hearts. | American journal of physiology. Cell physiology 20070501 |
Physiology of the yeast Kluyveromyces marxianus during batch and chemostat cultures with glucose as the sole carbon source. | FEMS yeast research 20070501 |
A fundamental dual regulatory role of citrate on the biosyntheses of thuringiensin and poly-beta-hydroxybutyrate in Bacillus thuringiensis YBT-032. | Biotechnology letters 20070501 |
The post-translational phenotype of collagen synthesized by SAOS-2 osteosarcoma cells. | Bone 20070501 |
Novel enzyme reactions related to the tricarboxylic acid cycle: phylogenetic/functional implications and biotechnological applications. | Applied microbiology and biotechnology 20070501 |
Manganese speciation in human cerebrospinal fluid using CZE coupled to inductively coupled plasma MS. | Electrophoresis 20070501 |
Association of candidate gene polymorphisms with bone mineral density in community-dwelling Japanese women and men. | International journal of molecular medicine 20070501 |
The activity of adenylyltransferase in Rhodospirillum rubrum is only affected by alpha-ketoglutarate and unmodified PII proteins, but not by glutamine, in vitro. | The FEBS journal 20070501 |
Identification of a novel PP2C-type mitochondrial phosphatase. | Biochemical and biophysical research communications 20070427 |
Alteration of DMBA-induced oxidative stress by additive action of a modified indigenous preparation--Kalpaamruthaa. | Chemico-biological interactions 20070425 |
Activation and coupling of the glutaminase and synthase reaction of glutamate synthase is mediated by E1013 of the ferredoxin-dependent enzyme, belonging to loop 4 of the synthase domain. | Biochemistry 20070417 |
Repair of methyl lesions in DNA and RNA by oxidative demethylation. | Neuroscience 20070414 |
How a single T cell receptor recognizes both self and foreign MHC. | Cell 20070406 |
Structure-function analysis of glutamine synthetase adenylyltransferase (ATase, EC 2.7.7.49) of Escherichia coli. | Biochemistry 20070403 |
Escherichia coli glutamine synthetase adenylyltransferase (ATase, EC 2.7.7.49): kinetic characterization of regulation by PII, PII-UMP, glutamine, and alpha-ketoglutarate. | Biochemistry 20070403 |
Evidence for a higher glycolytic than oxidative metabolic activity in white matter of rat brain. | Neurochemistry international 20070401 |
Exclusion of OGDH and BMP4 as candidate genes in two siblings with autosomal recessive DOOR syndrome. | American journal of medical genetics. Part A 20070401 |
A gene duplication led to specialized gamma-aminobutyrate and beta-alanine aminotransferase in yeast. | The FEBS journal 20070401 |
Interaction of Epe1 with the heterochromatin assembly pathway in Schizosaccharomyces pombe. | Genetics 20070401 |
Effect of cadmium on chlorophyll biosynthesis and enzymes of nitrogen assimilation in greening maize leaf segments: role of 2-oxoglutarate. | Indian journal of experimental biology 20070401 |
Oxalomalate affects the inducible nitric oxide synthase expression and activity. | Life sciences 20070313 |
Tissue-specific changes in the hydroxylysine content and cross-links of collagens and alterations in fibril morphology in lysyl hydroxylase 1 knock-out mice. | The Journal of biological chemistry 20070302 |
alpha-ketoglutaric semialdehyde dehydrogenase isozymes involved in metabolic pathways of D-glucarate, D-galactarate, and hydroxy-L-proline. Molecular and metabolic convergent evolution. | The Journal of biological chemistry 20070302 |
Functional analysis of norcoclaurine synthase in Coptis japonica. | The Journal of biological chemistry 20070302 |
Poly-beta-hydroxybutyrate accumulation in Nostoc muscorum: effects of metabolic inhibitors. | Journal of plant physiology 20070301 |
Thermal stability and biochemical properties of isocitrate dehydrogenase from the thermoacidophilic archaeon Thermoplasma acidophilum. | Extremophiles : life under extreme conditions 20070301 |
Differential effects of selenium compounds on glucose synthesis in rabbit kidney-cortex tubules and hepatocytes. In vitro and in vivo studies. | Journal of inorganic biochemistry 20070301 |
Effect of ornithine alpha-ketoglutarate on glutamine pools in burn injury: evidence of component interaction. | Intensive care medicine 20070301 |
Downregulation of organic anion transporters in rat kidney under ischemia/reperfusion-induced acute [corrected] renal failure. | Kidney international 20070301 |
Erythropoietin after a century of research: younger than ever. | European journal of haematology 20070301 |
Simultaneous measurement of D-serine dehydratase and d-amino acid oxidase activities by the detection of 2-oxo-acid formation with reverse-phase high-performance liquid chromatography. | Analytical biochemistry 20070301 |
Prolyl 3-hydroxylase 1 deficiency causes a recessive metabolic bone disorder resembling lethal/severe osteogenesis imperfecta. | Nature genetics 20070301 |
Non-heme dioxygenases: cellular sensors and regulators jelly rolled into one? | Nature chemical biology 20070301 |
Enzymatic and metabolic evidence for a region specific mitochondrial dysfunction in brains of murine succinic semialdehyde dehydrogenase deficiency (Aldh5a1-/- mice). | Neurochemistry international 20070301 |
Alanine aminotransferase catalyses the breakdown of alanine after hypoxia in Arabidopsis thaliana. | The Plant journal : for cell and molecular biology 20070301 |
A statistical approach using L(25) orthogonal array method to study fermentative production of clavulanic acid by Streptomyces clavuligerus MTCC 1142. | Applied biochemistry and biotechnology 20070301 |
Alpha-ketoglutarate decreases serum levels of C-terminal cross-linking telopeptide of type I collagen (CTX) in postmenopausal women with osteopenia: six-month study. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20070301 |
Characterization of the 2-hydroxy-acid dehydrogenase McyI, encoded within the microcystin biosynthesis gene cluster of Microcystis aeruginosa PCC7806. | The Journal of biological chemistry 20070216 |
Toward an improved understanding of the glutamate mutase system. | Journal of the American Chemical Society 20070214 |
S-allylcysteine ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing cardiac mitochondrial and lysosomal enzymes. | Life sciences 20070213 |
HIF and fumarate hydratase in renal cancer. | British journal of cancer 20070212 |
Molecular mechanism of the regulation of Bacillus subtilis gltAB expression by GltC. | Journal of molecular biology 20070202 |
Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates. | The Journal of biological chemistry 20070202 |
Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids. | Clinica chimica acta; international journal of clinical chemistry 20070201 |
Glutamine supplementation in the newborn infant. | Seminars in fetal & neonatal medicine 20070201 |
Expression of cytosolic branched chain aminotransferase (BCATc) mRNA in the developing mouse brain. | Gene expression patterns : GEP 20070201 |
Two interconverting Fe(IV) intermediates in aliphatic chlorination by the halogenase CytC3. | Nature chemical biology 20070201 |
The most versatile of all reactive intermediates? | Nature chemical biology 20070201 |
Folding and turnover of human iron regulatory protein 1 depend on its subcellular localization. | The FEBS journal 20070201 |
Global gene expression analysis of glucose overflow metabolism in Escherichia coli and reduction of aerobic acetate formation. | Applied microbiology and biotechnology 20070201 |
N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology. | Progress in neurobiology 20070201 |
Effect of pre-treatment of alpha-ketoglutarate on cyanide-induced toxicity and alterations in various physiological variables in rodents. | Biomedical and environmental sciences : BES 20070201 |
Structure of GlnK1 with bound effectors indicates regulatory mechanism for ammonia uptake. | The EMBO journal 20070124 |
Development and validation of a liquid chromatographic method for the determination of hydroxymethylfurfural and alpha-ketoglutaric acid in human plasma. | Analytica chimica acta 20070109 |
Adriamycin induced myocardial failure in rats: protective role of Centella asiatica. | Molecular and cellular biochemistry 20070101 |
Regulation of mitochondrial NADP-isocitrate dehydrogenase in rat heart during ischemia. | Molecular and cellular biochemistry 20070101 |
Lipoic acid as a novel treatment for Alzheimer's disease and related dementias. | Pharmacology & therapeutics 20070101 |
Redistribution of carbon flux in Torulopsis glabrata by altering vitamin and calcium level. | Metabolic engineering 20070101 |
Genomic structure and embryonic expression of zebrafish lysyl hydroxylase 1 and lysyl hydroxylase 2. | Matrix biology : journal of the International Society for Matrix Biology 20070101 |
Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101 |
Tobacco isoenzyme 1 of NAD(H)-dependent glutamate dehydrogenase catabolizes glutamate in vivo. | Plant physiology 20070101 |
Glutamine signalling in bacteria. | Frontiers in bioscience : a journal and virtual library 20070101 |
Does the ornithine-alpha-ketoglutarate ratio influence ornithine alpha-ketoglutarate metabolism in healthy rats? | Metabolism: clinical and experimental 20070101 |
Characterization of Bacillus subtilis mutants with carbon source-independent glutamate biosynthesis. | Journal of molecular microbiology and biotechnology 20070101 |
The proteomic profile of Fusobacterium nucleatum is regulated by growth pH. | Microbiology (Reading, England) 20070101 |
Tetrahydrobiopterin availability in Parkinson's and Alzheimer's disease; potential pathogenic mechanisms. | Neurochemical research 20070101 |
Integration of regulatory signals through involvement of multiple global regulators: control of the Escherichia coli gltBDF operon by Lrp, IHF, Crp, and ArgR. | BMC microbiology 20070101 |
Identification of candidate methylation-responsive genes in ovarian cancer. | Molecular cancer 20070101 |
Electrochemical regeneration of NADH using conductive vanadia-silica xerogels. | Biotechnology progress 20070101 |
Fluxome analysis using GC-MS. | Microbial cell factories 20070101 |
Branched chain keto-acids exert biphasic effects on alpha-ketoglutarate-stimulated respiration in intact rat liver mitochondria. | Neurochemical research 20070101 |
Hypoxia inducible factor prolyl 4-hydroxylase enzymes: center stage in the battle against hypoxia, metabolic compromise and oxidative stress. | Neurochemical research 20070101 |
Genome analysis of DNA repair genes in the alpha proteobacterium Caulobacter crescentus. | BMC microbiology 20070101 |
Metabolic modeling of a mutualistic microbial community. | Molecular systems biology 20070101 |
A network perspective on the topological importance of enzymes and their phylogenetic conservation. | BMC bioinformatics 20070101 |
[Simultaneous determination of twenty-one organic acids in food by ion chromatography with eluent autogeneration]. | Se pu = Chinese journal of chromatography 20070101 |
Growth control of the eukaryote cell: a systems biology study in yeast. | Journal of biology 20070101 |
Biochemical assays for mitochondrial activity: assays of TCA cycle enzymes and PDHc. | Methods in cell biology 20070101 |
Multilevel regulation of growth rate in yeast revealed using systems biology. | Journal of biology 20070101 |
A search engine to identify pathway genes from expression data on multiple organisms. | BMC systems biology 20070101 |
Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite. | PloS one 20070101 |
Nitrogen regulation in bacteria and archaea. | Annual review of microbiology 20070101 |
13CO2 as a universal metabolic tracer in isotopologue perturbation experiments. | Phytochemistry 20070101 |
Brucella suis urease encoded by ure1 but not ure2 is necessary for intestinal infection of BALB/c mice. | BMC microbiology 20070101 |
Glutamate in plants: metabolism, regulation, and signalling. | Journal of experimental botany 20070101 |
Study on roles of anaplerotic pathways in glutamate overproduction of Corynebacterium glutamicum by metabolic flux analysis. | Microbial cell factories 20070101 |
Observing metabolic functions at the genome scale. | Genome biology 20070101 |
Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine. | Research in microbiology 20070101 |
Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes. | Genome biology 20070101 |
Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli. | Molecular systems biology 20070101 |
An analysis of expression patterns of genes encoding proteins with catalytic activities. | BMC genomics 20070101 |
Hydroxylation of hypoxia-inducible transcription factors and chemical compounds targeting the HIF-alpha hydroxylases. | Current medicinal chemistry 20070101 |
Comparative proteomics reveal characteristics of life-history transitions in a social insect. | Proteome science 20070101 |
Expression profile of proteins involved in scar formation in the healing process of full-thickness excisional wounds in the porcine model. | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101 |
Identification of gene targets against dormant phase Mycobacterium tuberculosis infections. | BMC infectious diseases 20070101 |
The tricarboxylic acid cycle, an ancient metabolic network with a novel twist. | PloS one 20070101 |
The primordial metabolism: an ancestral interconnection between leucine, arginine, and lysine biosynthesis. | BMC evolutionary biology 20070101 |
Metabolic peculiarities of Aspergillus niger disclosed by comparative metabolic genomics. | Genome biology 20070101 |
Molecular and structural discrimination of proline racemase and hydroxyproline-2-epimerase from nosocomial and bacterial pathogens. | PloS one 20070101 |
Comparative proteome analysis of human epithelial ovarian cancer. | Proteome science 20070101 |
Horizontal gene transfer in chromalveolates. | BMC evolutionary biology 20070101 |
Cadmium triggers an integrated reprogramming of the metabolism of Synechocystis PCC6803, under the control of the Slr1738 regulator. | BMC genomics 20070101 |
Host origin of plastid solute transporters in the first photosynthetic eukaryotes. | Genome biology 20070101 |
Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons. | BMC neuroscience 20070101 |
Fasting induces a biphasic adaptive metabolic response in murine small intestine. | BMC genomics 20070101 |
Visualizing regulatory interactions in metabolic networks. | BMC biology 20070101 |
Effects of iron loading on muscle: genome-wide mRNA expression profiling in the mouse. | BMC genomics 20070101 |
Long-term abnormalities in brain glucose/energy metabolism after inhibition of the neuronal insulin receptor: implication of tau-protein. | Journal of neural transmission. Supplementum 20070101 |
[Characteristic metabolic disturbances in the rat tissues caused by long-term use of alcohol]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101 |
UV-B-induced signaling events leading to enhanced-production of catharanthine in Catharanthus roseus cell suspension cultures. | BMC plant biology 20070101 |
Preventive effect of naringin on cardiac mitochondrial enzymes during isoproterenol-induced myocardial infarction in rats: a transmission electron microscopic study. | Journal of biochemical and molecular toxicology 20070101 |
The FTO (fat mass and obesity associated) gene codes for a novel member of the non-heme dioxygenase superfamily. | BMC biochemistry 20070101 |
Characterization of ankyrin repeat-containing proteins as substrates of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible transcription factor. | Methods in enzymology 20070101 |
Rapid changes in gene expression dynamics in response to superoxide reveal SoxRS-dependent and independent transcriptional networks. | PloS one 20070101 |
Promoter analysis of intestinal genes induced during iron-deprivation reveals enrichment of conserved SP1-like binding sites. | BMC genomics 20070101 |
Unbiased characterization of genotype-dependent metabolic regulations by metabolomic approach in Arabidopsis thaliana. | BMC systems biology 20070101 |
[Effect of cadmium sulphate on the metabolism of carbohydrates in organism of rats of different ages]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101 |
Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis. | BMC bioinformatics 20070101 |
The oncoprotein H-RasV12 increases mitochondrial metabolism. | Molecular cancer 20070101 |
Sucrose phosphate synthase activity and the co-ordination of carbon partitioning during sucrose and amino acid accumulation in desiccation-tolerant leaf material of the C4 resurrection plant Sporobolus stapfianus during dehydration. | Journal of experimental botany 20070101 |
Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice. | BMC genomics 20070101 |
The plasticizer butyl benzyl phthalate induces genomic changes in rat mammary gland after neonatal/prepubertal exposure. | BMC genomics 20070101 |
Reconstruction and flux analysis of coupling between metabolic pathways of astrocytes and neurons: application to cerebral hypoxia. | Theoretical biology & medical modelling 20070101 |
Gene expression profile in obesity and type 2 diabetes mellitus. | Lipids in health and disease 20070101 |
Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions. | Critical care (London, England) 20070101 |
Microarray analysis of iron deficiency chlorosis in near-isogenic soybean lines. | BMC genomics 20070101 |
The complete genome sequence and analysis of the epsilonproteobacterium Arcobacter butzleri. | PloS one 20070101 |
Breast tumour angiogenesis. | Breast cancer research : BCR 20070101 |
[Decrease of phosphate concentration in the medium by Brevibacterium casei cells]. | Mikrobiologiia 20070101 |
[Activity of oil isolated from Amaranth seeds on energetic functions of rat liver mitochondria after adrenaline introduction]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20070101 |
[L-2-hydroxyglutaric aciduria, an error of metabolism]. | Bulletin et memoires de l'Academie royale de medecine de Belgique 20070101 |
Attenuation of mitochondrial injury by L-arginine preconditioning of the liver. | BioFactors (Oxford, England) 20070101 |
Increased endogenous nitric oxide release by iron chelation and purinergic activation in the rat carotid body. | The open biochemistry journal 20070101 |
Driving parts of Krebs cycle in reverse through mineral photochemistry. | Journal of the American Chemical Society 20061220 |
Mutation-induced metabolite pool alterations in Corynebacterium glutamicum: towards the identification of nitrogen control signals. | Journal of biotechnology 20061201 |
Aging: a shift from redox regulation to oxidative damage. | Free radical research 20061201 |
The genome of deep-sea vent chemolithoautotroph Thiomicrospira crunogena XCL-2. | PLoS biology 20061201 |
The human malaria parasite Plasmodium falciparum expresses an atypical N-terminally extended pyrophosphokinase with specificity for thiamine. | Biological chemistry 20061201 |
Interaction of the membrane-bound GlnK-AmtB complex with the master regulator of nitrogen metabolism TnrA in Bacillus subtilis. | The Journal of biological chemistry 20061117 |
Oxo-4-methylpentanoic acid directs the metabolism of GABA into the Krebs cycle in rat pancreatic islets. | The Biochemical journal 20061115 |
Biochemical and functional modulation of the cartilage collagen network by IGF1, TGFbeta2 and FGF2. | Osteoarthritis and cartilage 20061101 |
2-Oxoglutarate downregulates expression of vascular endothelial growth factor and erythropoietin through decreasing hypoxia-inducible factor-1alpha and inhibits angiogenesis. | Journal of cellular physiology 20061101 |
Functional diversity of lysyl hydroxylase 2 in collagen synthesis of human dermal fibroblasts. | Experimental cell research 20061101 |
Glutamate:glyoxylate aminotransferase modulates amino acid content during photorespiration. | Plant physiology 20061101 |
Dactylorhin B reduces toxic effects of beta-amyloid fragment (25-35) on neuron cells and isolated rat brain mitochondria. | Naunyn-Schmiedeberg's archives of pharmacology 20061101 |
A novel oxalosuccinate-forming enzyme involved in the reductive carboxylation of 2-oxoglutarate in Hydrogenobacter thermophilus TK-6. | Molecular microbiology 20061101 |
Impact of the C-N status on the amino acid profile in tobacco source leaves. | Plant, cell & environment 20061101 |
[Gas liquid chromatographic determination of tricarbonic cycle acids in human plasma]. | Klinicheskaia laboratornaia diagnostika 20061101 |
Mitochondrial glutathione transport: physiological, pathological and toxicological implications. | Chemico-biological interactions 20061027 |
Mitochondrial function and toxicity: role of the B vitamin family on mitochondrial energy metabolism. | Chemico-biological interactions 20061027 |
Ferulic acid with ascorbic acid synergistically extenuates the mitochondrial dysfunction during beta-adrenergic catecholamine induced cardiotoxicity in rats. | Chemico-biological interactions 20061027 |
Free radical scavenging activity of the marine mangrove Rhizophora apiculata bark extract with reference to naphthalene induced mitochondrial dysfunction. | Chemico-biological interactions 20061027 |
Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier. | The Journal of biological chemistry 20061020 |
CRTAP is required for prolyl 3- hydroxylation and mutations cause recessive osteogenesis imperfecta. | Cell 20061020 |
Functional and structural role of amino acid residues in the even-numbered transmembrane alpha-helices of the bovine mitochondrial oxoglutarate carrier. | Journal of molecular biology 20061013 |
In vitro analysis of the Escherichia coli AmtB-GlnK complex reveals a stoichiometric interaction and sensitivity to ATP and 2-oxoglutarate. | The Journal of biological chemistry 20061006 |
First identification of a 2-ketoglutarate/isocitrate transport system in mammalian peroxisomes and its characterization. | Biochemical and biophysical research communications 20061006 |
Direct evidence for a glutamate switch necessary for substrate recognition: crystal structures of lysine epsilon-aminotransferase (Rv3290c) from Mycobacterium tuberculosis H37Rv. | Journal of molecular biology 20061006 |
Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae. | Biochemistry 20061003 |
Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae. | Biochemistry 20061003 |
Posttranslational hydroxylation of ankyrin repeats in IkappaB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH). | Proceedings of the National Academy of Sciences of the United States of America 20061003 |
Retrovirus producer cell line metabolism: implications on viral productivity. | Applied microbiology and biotechnology 20061001 |
Activation of ERK1/2 pathway mediates oxidant-induced decreases in mitochondrial function in renal cells. | American journal of physiology. Renal physiology 20061001 |
Evaluation of metabolic alteration in transgenic rice overexpressing dihydroflavonol-4-reductase. | Annals of botany 20061001 |
Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models. | Diabetologia 20061001 |
Restorative effect of Kalpaamruthaa, an indigenous preparation, on oxidative damage in mammary gland mitochondrial fraction in experimental mammary carcinoma. | Molecular and cellular biochemistry 20061001 |
Metabolic normalization of alpha-ketoglutarate against N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. | Fundamental & clinical pharmacology 20061001 |
The lysyl hydroxylase isoforms are widely expressed during mouse embryogenesis, but obtain tissue- and cell-specific patterns in the adult. | Matrix biology : journal of the International Society for Matrix Biology 20061001 |
Hypoxia-induced erythropoietin production: a paradigm for oxygen-regulated gene expression. | Clinical and experimental pharmacology & physiology 20061001 |
Cloning, purification, crystallization and preliminary X-ray crystallographic analysis of the biosynthetic N-acetylornithine aminotransferases from Salmonella typhimurium and Escherichia coli. | Acta crystallographica. Section F, Structural biology and crystallization communications 20061001 |
Abiotic stress generates ROS that signal expression of anionic glutamate dehydrogenases to form glutamate for proline synthesis in tobacco and grapevine. | The Plant cell 20061001 |
Kinetic model of mitochondrial Krebs cycle: unraveling the mechanism of salicylate hepatotoxic effects. | Journal of biological physics 20061001 |
A novel alpha-ketoglutaric semialdehyde dehydrogenase: evolutionary insight into an alternative pathway of bacterial L-arabinose metabolism. | The Journal of biological chemistry 20060929 |
Identification and mRNA expression of Ogdh, QP-C, and two predicted genes in the postnatal mouse brain. | Neuroscience letters 20060925 |
Identification of the missing links in prokaryotic pentose oxidation pathways: evidence for enzyme recruitment. | The Journal of biological chemistry 20060915 |
Cytosolic branched chain aminotransferase (BCATc) mRNA is up-regulated in restricted brain areas of BDNF transgenic mice. | Brain research 20060907 |
Preconditioning prevents loss in mitochondrial function and release of cytochrome c during prolonged cardiac ischemia/reperfusion. | Archives of biochemistry and biophysics 20060901 |
Ammonia permeability of the aquaglyceroporins from Plasmodium falciparum, Toxoplasma gondii and Trypansoma brucei. | Molecular microbiology 20060901 |
Pharmacokinetics, safety, and effects on exercise performance of L-arginine alpha-ketoglutarate in trained adult men. | Nutrition (Burbank, Los Angeles County, Calif.) 20060901 |
A metabonomics study of the hepatotoxicants galactosamine, methylene dianiline and clofibrate in rats. | Basic & clinical pharmacology & toxicology 20060901 |
Characterization of salicylate uptake across the basolateral membrane of the malpighian tubules of Drosophila melanogaster. | Journal of insect physiology 20060901 |
Biosynthesis of the (2S,3R)-3-methyl glutamate residue of nonribosomal lipopeptides. | Journal of the American Chemical Society 20060830 |
Study of a novel indolin-2-ketone compound Z24 induced hepatotoxicity by NMR-spectroscopy-based metabonomics of rat urine, blood plasma, and liver extracts. | Toxicology and applied pharmacology 20060815 |
Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins. | The Biochemical journal 20060815 |
A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 alpha. | Journal of cell science 20060815 |
Cellular differentiation determines the expression of the hypoxia-inducible protein NDRG1 in pancreatic cancer. | British journal of cancer 20060807 |
Modifications of the lipoamide-containing mitochondrial subproteome in a yeast mutant defective in cysteine desulfurase. | Molecular & cellular proteomics : MCP 20060801 |
RS-alpha-lipoic acid protects cholinergic cells against sodium nitroprusside and amyloid-beta neurotoxicity through restoration of acetyl-CoA level. | Journal of neurochemistry 20060801 |
Ammonium chloride and alpha-ketoglutaric acid increase glutamine availability in the early phase of induced acute metabolic acidosis. | Acta anaesthesiologica Scandinavica 20060801 |
Nitrogen source and the retrograde signalling pathway affect detection, not generation, of the [URE3] prion. | Yeast (Chichester, England) 20060801 |
Studying the signaling role of 2-oxoglutaric acid using analogs that mimic the ketone and ketal forms of 2-oxoglutaric acid. | Chemistry & biology 20060801 |
Effect of maternal dexamethasone and alpha-ketoglutarate administration on skeletal development during the last three weeks of prenatal life in pigs. | The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 20060801 |
Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage. | The EMBO journal 20060726 |
Cisplatin-induced toxicity is associated with platinum deposition in mouse kidney mitochondria in vivo and with selective inactivation of the alpha-ketoglutarate dehydrogenase complex in LLC-PK1 cells. | Biochemistry 20060725 |
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3. | Nature 20060720 |
Inactivation of GABA transaminase by 4-acryloylphenol. | Bioorganic & medicinal chemistry letters 20060715 |
The good, the bad and the ugly in oxygen-sensing: ROS, cytochromes and prolyl-hydroxylases. | Cardiovascular research 20060715 |
Ornithine alpha-ketoglutarate increases mineralization and mechanical properties of tibia in turkeys. | Bone 20060701 |
The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates. | The Biochemical journal 20060701 |
On-line optimization of glutamate production based on balanced metabolic control by RQ. | Bioprocess and biosystems engineering 20060701 |
Metabolic pathway analysis for rational design of L-methionine production by Escherichia coli and Corynebacterium glutamicum. | Metabolic engineering 20060701 |
The crystal structure of a hyperthermostable subfamily II isocitrate dehydrogenase from Thermotoga maritima. | The FEBS journal 20060701 |
A shortcut to mitochondrial signaling and pathology: a commentary on 'Nonenzymatic formation of succinate in mitochondria under oxidative stress'. | Free radical biology & medicine 20060701 |
Nonezymatic formation of succinate in mitochondria under oxidative stress. | Free radical biology & medicine 20060701 |
Interaction network in cyanobacterial nitrogen regulation: PipX, a protein that interacts in a 2-oxoglutarate dependent manner with PII and NtcA. | Molecular microbiology 20060701 |
Purification and characterization of two enantioselective alpha-ketoglutarate-dependent dioxygenases, RdpA and SdpA, from Sphingomonas herbicidovorans MH. | Applied and environmental microbiology 20060701 |
Cytosolic heat shock proteins and heme oxygenase-1 are preferentially induced in response to specific and localized intramitochondrial damage by tetrafluoroethylcysteine. | Biochemical pharmacology 20060628 |
Free radical-mediated neurotoxicity may be caused by inhibition of mitochondrial dehydrogenases in vitro and in vivo. | Neuroscience 20060619 |
Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid. | FEBS letters 20060612 |
Heme oxygenase-1 enhances renal mitochondrial transport carriers and cytochrome C oxidase activity in experimental diabetes. | The Journal of biological chemistry 20060609 |
Concordant regulation of gene expression by hypoxia and 2-oxoglutarate-dependent dioxygenase inhibition: the role of HIF-1alpha, HIF-2alpha, and other pathways. | The Journal of biological chemistry 20060602 |
Changes in oxygen consumption and respiratory enzymes as stress indicators in an estuarine edible crab Scylla serrata exposed to naphthalene. | Chemosphere 20060601 |
Intraduodenal infusion of alpha-ketoglutarate decreases whole body energy expenditure in growing pigs. | Clinical nutrition (Edinburgh, Scotland) 20060601 |
Activities of membrane bound phosphatases, transaminases and mitochondrial enzymes in white spot syndrome virus infected tissues of Fenneropenaeus indicus. | Virus research 20060601 |
Lysyl hydroxylase 3 (LH3) modifies proteins in the extracellular space, a novel mechanism for matrix remodeling. | Journal of cellular physiology 20060601 |
Proteome analysis of Halobacterium sp. NRC-1 facilitated by the biomodule analysis tool BMSorter. | Molecular & cellular proteomics : MCP 20060601 |
Combined transcript and metabolite profiling of Arabidopsis leaves reveals fundamental effects of the thiol-disulfide status on plant metabolism. | Plant physiology 20060601 |
Acrolein is a mitochondrial toxin: effects on respiratory function and enzyme activities in isolated rat liver mitochondria. | Mitochondrion 20060601 |
The myotomal diwanka (lh3) glycosyltransferase and type XVIII collagen are critical for motor growth cone migration. | Neuron 20060601 |
Structural basis for the enantiospecificities of R- and S-specific phenoxypropionate/alpha-ketoglutarate dioxygenases. | Protein science : a publication of the Protein Society 20060601 |
Peroxynitrite as an alternative donor of oxygen in HIF-1alpha proline hydroxylation under low oxygen availability. | Free radical research 20060601 |
Structure of the PII signal transduction protein of Neisseria meningitidis at 1.85 A resolution. | Acta crystallographica. Section F, Structural biology and crystallization communications 20060601 |
Relative contribution of OAT1 and OAT3 transport activities in isolated perfused rabbit renal proximal tubules. | Biochimica et biophysica acta 20060601 |
Molecular cloning and characterization of a large subunit of Salmonella typhimurium glutamate synthase (GOGAT) gene in Escherichia coli. | Journal of microbiology (Seoul, Korea) 20060601 |
Diffusion-Weighted MRI in Recurrent Wernicke's Encephalopathy: a Remarkable Cerebellar Lesion. | Journal of clinical neurology (Seoul, Korea) 20060601 |
Influence of peptide supply and cosubstrates on phenylalanine metabolism of Lactobacillus sanfranciscensis DSM20451(T) and Lactobacillus plantarum TMW1.468. | Journal of agricultural and food chemistry 20060531 |
Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlH, a non-heme iron dioxygenase of Streptomyces avermitilis. | Journal of the American Chemical Society 20060524 |
Structural insights into histone demethylation by JMJD2 family members. | Cell 20060519 |
13C magnetic resonance spectroscopy studies of alterations in glutamate neurotransmission. | Biological psychiatry 20060515 |
Corynebacterial protein kinase G controls 2-oxoglutarate dehydrogenase activity via the phosphorylation status of the OdhI protein. | The Journal of biological chemistry 20060505 |
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor. | Cell 20060505 |
Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron. | Biochimie 20060501 |
D-2-hydroxyglutaric aciduria in three patients with proven SSADH deficiency: genetic coincidence or a related biochemical epiphenomenon? | Molecular genetics and metabolism 20060501 |
Development of a kinetic metabolic model: application to Catharanthus roseus hairy root. | Bioprocess and biosystems engineering 20060501 |
Variation of milk citrate with stage of lactation and de novo fatty acid synthesis in dairy cows. | Journal of dairy science 20060501 |
Gene expression of Corynebacterium glutamicum in response to the conditions inducing glutamate overproduction. | Letters in applied microbiology 20060501 |
Expression of cytosolic NADP+-dependent isocitrate dehydrogenase in bovine mammary epithelium: Modulation by regulators of differentiation and metabolic effectors. | Experimental biology and medicine (Maywood, N.J.) 20060501 |
Metabolic characteristics of recombinant Chinese hamster ovary cells expressing glutamine synthetase in presence and absence of glutamine. | Cytotechnology 20060501 |
Epimerization and desaturation by carbapenem synthase (CarC). A hybrid DFT study. | Journal of computational chemistry 20060430 |
Hypobaric hypoxia affects endogenous levels of alpha-keto acids in murine heart ventricles. | Biochemical and biophysical research communications 20060414 |
Functional characterization of Na+ -coupled citrate transporter NaC2/NaCT expressed in primary cultures of neurons from mouse cerebral cortex. | Brain research 20060407 |
Cardiotoxicity of copper-based antineoplastic drugs casiopeinas is related to inhibition of energy metabolism. | Toxicology and applied pharmacology 20060401 |
Gene cloning, heterologous overexpression and optimized refolding of the NAD-glutamate dehydrogenase from Haloferax mediterranei. | Extremophiles : life under extreme conditions 20060401 |
Substrate-free structure of a monomeric NADP isocitrate dehydrogenase: an open conformation phylogenetic relationship of isocitrate dehydrogenase. | Proteins 20060401 |
Oxidative dealkylation DNA repair mediated by the mononuclear non-heme iron AlkB proteins. | Journal of inorganic biochemistry 20060401 |
Structural studies on 2-oxoglutarate oxygenases and related double-stranded beta-helix fold proteins. | Journal of inorganic biochemistry 20060401 |
Theoretical analysis of carbon-13 magnetization transfer for in vivo exchange between alpha-ketoglutarate and glutamate. | NMR in biomedicine 20060401 |
Control of carbon flux through enzymes of central and intermediary metabolism during growth of Escherichia coli on acetate. | Current opinion in microbiology 20060401 |
Pathways of carbon assimilation and ammonia oxidation suggested by environmental genomic analyses of marine Crenarchaeota. | PLoS biology 20060401 |
The effect of aging on anaerobic and aerobic enzyme activities in human skeletal muscle. | The journals of gerontology. Series A, Biological sciences and medical sciences 20060401 |
Quantum chemical modeling of reaction mechanism for 2-oxoglutarate dependent enzymes: effect of substitution of iron by nickel and cobalt. | The journal of physical chemistry. A 20060330 |
Effect of lpdA gene knockout on the metabolism in Escherichia coli based on enzyme activities, intracellular metabolite concentrations and metabolic flux analysis by 13C-labeling experiments. | Journal of biotechnology 20060323 |
Crystal structure of the non-haem iron halogenase SyrB2 in syringomycin biosynthesis. | Nature 20060316 |
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines. | British journal of cancer 20060313 |
Glucose inhibits GABA release by pancreatic beta-cells through an increase in GABA shunt activity. | American journal of physiology. Endocrinology and metabolism 20060301 |
Modulation of expression of rat mitochondrial 2-oxoglutarate carrier in NRK-52E cells alters mitochondrial transport and accumulation of glutathione and susceptibility to chemically induced apoptosis. | The Journal of pharmacology and experimental therapeutics 20060301 |
Control of the synthesis and subcellular targeting of the two GDH genes products in leaves and stems of Nicotiana plumbaginifolia and Arabidopsis thaliana. | Plant & cell physiology 20060301 |
Salt stress adaptation of Bacillus subtilis: a physiological proteomics approach. | Proteomics 20060301 |
Metabolomic and bioinformatic analyses in asphyxiated neonates. | Clinical biochemistry 20060301 |
A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD. | Molecular microbiology 20060301 |
Levetiracetam: antiepileptic properties and protective effects on mitochondrial dysfunction in experimental status epilepticus. | Epilepsia 20060301 |
A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and its derivatives. | Evidence-based complementary and alternative medicine : eCAM 20060301 |
Cerebral metabolism in brains of rats infected with neuropathogenic murine leukemia viruses. | The Journal of veterinary medical science 20060301 |
Analysis of ingested material and urine by GC-MS and 1H NMR spectroscopy: poisoning of an adult with adulterated soda. | Journal of analytical toxicology 20060301 |
Vitamins in aging, health, and longevity. | Clinical interventions in aging 20060301 |
Negative mode sheathless capillary electrophoresis electrospray ionization-mass spectrometry for metabolite analysis of prokaryotes. | Journal of chromatography. A 20060217 |
Histone demethylation by a family of JmjC domain-containing proteins. | Nature 20060216 |
Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB. | Nature 20060216 |
Inhibitors of the alpha-ketoglutarate dehydrogenase complex alter [1-13C]glucose and [U-13C]glutamate metabolism in cerebellar granule neurons. | Journal of neuroscience research 20060215 |
Glycosylation catalyzed by lysyl hydroxylase 3 is essential for basement membranes. | Journal of cell science 20060215 |
Cloning, expression, and characterization of bacterial L-arabinose 1-dehydrogenase involved in an alternative pathway of L-arabinose metabolism. | The Journal of biological chemistry 20060203 |
Accumulation of nonesterified fatty acids causes the sustained energetic deficit in kidney proximal tubules after hypoxia-reoxygenation. | American journal of physiology. Renal physiology 20060201 |
Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters. | Pflugers Archiv : European journal of physiology 20060201 |
Inhibition of GABA shunt enzymes' activity by 4-hydroxybenzaldehyde derivatives. | Bioorganic & medicinal chemistry letters 20060201 |
Biochemical characterization of the glutamate transport in Trypanosoma cruzi. | International journal for parasitology 20060201 |
Glutamine synthetase-glutamate synthase pathway and glutamate dehydrogenase play distinct roles in the sink-source nitrogen cycle in tobacco. | Plant physiology 20060201 |
Calcium, mitochondria and oxidative stress in neuronal pathology. Novel aspects of an enduring theme. | The FEBS journal 20060201 |
Regulation of 2-oxoglutarate metabolism in rat liver by NADP-isocitrate dehydrogenase and aspartate aminotransferase. | Biochemistry. Biokhimiia 20060201 |
D-2-Hydroxyglutaric aciduria: unravelling the biochemical pathway and the genetic defect. | Journal of inherited metabolic disease 20060201 |
Effect of alpha-ketoglutarate on cyanide-induced biochemical alterations in rat brain and liver. | Biomedical and environmental sciences : BES 20060201 |
Preferential energy- and potential-dependent accumulation of cisplatin-gutathione complexes in human cancer cell lines (GLC4 and K562): A likely role of mitochondria. | Journal of bioenergetics and biomembranes 20060201 |
Cloning and characterization of a flavanone 3-hydroxylase gene from Ginkgo biloba. | Bioscience reports 20060201 |
Identification and kinetic characterization of HtDTC, the mitochondrial dicarboxylate-tricarboxylate carrier of Jerusalem artichoke tubers. | Journal of bioenergetics and biomembranes 20060201 |
Purifications and characterizations of a ferredoxin and its related 2-oxoacid:ferredoxin oxidoreductase from the hyperthermophilic archaeon, Sulfolobus solfataricus P1. | Journal of biochemistry and molecular biology 20060131 |
Modulation of TCA cycle enzymes and electron transport chain systems in experimental lung cancer. | Life sciences 20060125 |
Cellular mitochondrial heterogeneity in cultured astrocytes as demonstrated by immunogold labeling of alpha-ketoglutarate dehydrogenase. | Glia 20060115 |
Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice. | Mechanisms of ageing and development 20060101 |
Functional analysis through site-directed mutations and phylogeny of the Candida albicans LYS1-encoded saccharopine dehydrogenase. | Molecular genetics and genomics : MGG 20060101 |
Self-hydroxylation of taurine/alpha-ketoglutarate dioxygenase: evidence for more than one oxygen activation mechanism. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20060101 |
The RpoS-mediated regulation of isocitrate dehydrogenase gene expression in Escherichia coli. | Current microbiology 20060101 |
Antisense repression reveals a crucial role of the plastidic 2-oxoglutarate/malate translocator DiT1 at the interface between carbon and nitrogen metabolism. | The Plant journal : for cell and molecular biology 20060101 |
Redirecting carbon flux in Torulopsis glabrata from pyruvate to alpha-ketoglutaric acid by changing metabolic co-factors. | Biotechnology letters 20060101 |
Heterocyst differentiation and pattern formation in cyanobacteria: a chorus of signals. | Molecular microbiology 20060101 |
Excess casein in the diet is not the unique cause of low-grade metabolic acidosis: role of a deficit in potassium citrate in a rat model. | Annals of nutrition & metabolism 20060101 |
Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae. | FEMS yeast research 20060101 |
GPNN: power studies and applications of a neural network method for detecting gene-gene interactions in studies of human disease. | BMC bioinformatics 20060101 |
sucAB and sucCD are mutually essential genes in Escherichia coli. | FEMS microbiology letters 20060101 |
Release of Ca2+ and Mg2+ from yeast mitochondria is stimulated by increased ionic strength. | BMC biochemistry 20060101 |
A novel low molecular weight alanine aminotransferase from fasted rat liver. | Biochemistry. Biokhimiia 20060101 |
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms. | BMC bioinformatics 20060101 |
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes. | BMC bioinformatics 20060101 |
[Metabolism of recombinant CHO-GS cell reducing of toxic effect of ammonia]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060101 |
[Stimulatory effects of some amino acids on glycerol production by Candida glycerinogenes]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060101 |
Alpha-ketoglutarate modulates the circadian patterns of lipid peroxidation and antioxidant status during N-nitrosodiethylamine-induced hepatocarcinogenesis in rats. | Journal of medicinal food 20060101 |
Global gene expression analyses of hematopoietic stem cell-like cell lines with inducible Lhx2 expression. | BMC genomics 20060101 |
Mining gene expression data by interpreting principal components. | BMC bioinformatics 20060101 |
How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome. | Lipids in health and disease 20060101 |
N-acetylaspartate as a reservoir for glutamate. | Medical hypotheses 20060101 |
Association of PLOD1 polymorphisms with bone mineral density in a population-based study of women from the UK. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20060101 |
Direct removal of alkylation damage from DNA by AlkB and related DNA dioxygenases. | Methods in enzymology 20060101 |
Redox stress is not essential for the pseudo-hypoxic phenotype of succinate dehydrogenase deficient cells. | Biochimica et biophysica acta 20060101 |
Clustering of Pseudomonas aeruginosa transcriptomes from planktonic cultures, developing and mature biofilms reveals distinct expression profiles. | BMC genomics 20060101 |
MANET: tracing evolution of protein architecture in metabolic networks. | BMC bioinformatics 20060101 |
[Correlation between succinate-dependent Ca2+ accumulation and transamination in the heart and the liver mitochondria of experimental animals]. | Biomeditsinskaia khimiia 20060101 |
Aluminum toxicity elicits a dysfunctional TCA cycle and succinate accumulation in hepatocytes. | Journal of biochemical and molecular toxicology 20060101 |
[The influence of the fluorine-containing activators of mitochondrial adenosine triphosphate sensitive potassium channels on the oxidative phosphorilation]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20060101 |
Hierarchical modularity of nested bow-ties in metabolic networks. | BMC bioinformatics 20060101 |
Global gene expression during stringent response in Corynebacterium glutamicum in presence and absence of the rel gene encoding (p)ppGpp synthase. | BMC genomics 20060101 |
Integration of metabolome data with metabolic networks reveals reporter reactions. | Molecular systems biology 20060101 |
Global gene expression of Prochlorococcus ecotypes in response to changes in nitrogen availability. | Molecular systems biology 20060101 |
[Subcellular localization, purification, and various catalitic properties of aspartate aminotransferase from Spirodela polyrhiza]. | Izvestiia Akademii nauk. Seriia biologicheskaia 20060101 |
Comparative proteomic analysis of high cell density cultivations with two recombinant Bacillus megaterium strains for the production of a heterologous dextransucrase. | Proteome science 20060101 |
Circulating immune complexes and trace elements (Copper, Iron and Selenium) as markers in oral precancer and cancer : a randomised, controlled clinical trial. | Head & face medicine 20060101 |
Alterations of metabolic activity in human osteoarthritic osteoblasts by lipid peroxidation end product 4-hydroxynonenal. | Arthritis research & therapy 20060101 |
Mitochondrial oxidative damage in aging and Alzheimer's disease: implications for mitochondrially targeted antioxidant therapeutics. | Journal of biomedicine & biotechnology 20060101 |
The creatine kinase/creatine connection to Alzheimer's disease: CK-inactivation, APP-CK complexes and focal creatine deposits. | Journal of biomedicine & biotechnology 20060101 |
Effects of the presence of ColE1 plasmid DNA in Escherichia coli on the host cell metabolism. | Microbial cell factories 20060101 |
A computational analysis of the three isoforms of glutamate dehydrogenase reveals structural features of the isoform EC 1.4.1.4 supporting a key role in ammonium assimilation by plants. | Biology direct 20060101 |
[Catalytic properties of 6-phosphogluconate dehydrogenase from rat liver in normal state and during toxic hepatitis]. | Biomeditsinskaia khimiia 20060101 |
A low protein diet increases the hypoxic tolerance in Drosophila. | PloS one 20060101 |
Structure of a conserved hypothetical protein SA1388 from S. aureus reveals a capped hexameric toroid with two PII domain lids and a dinuclear metal center. | BMC structural biology 20060101 |
[Correction of mitochondrial respiration processes in rats with different resistance to hypoxia under stress by modulators of ATP-sensitive potassium channels]. | Biomeditsinskaia khimiia 20060101 |
Sodium fluoroacetate poisoning. | Toxicological reviews 20060101 |
The oxygen sensing signal cascade under the influence of reactive oxygen species. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20051229 |
Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20051229 |
Reversible inactivation of HIF-1 prolyl hydroxylases allows cell metabolism to control basal HIF-1. | The Journal of biological chemistry 20051223 |
A continuous spectrophotometric assay method for peptidylarginine deiminase type 4 activity. | Analytical biochemistry 20051215 |
Signalling hypoxia by HIF hydroxylases. | Biochemical and biophysical research communications 20051209 |
Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease. | The Journal of biological chemistry 20051209 |
Manganese superoxide dismutase suppresses hypoxic induction of hypoxia-inducible factor-1alpha and vascular endothelial growth factor. | Oncogene 20051208 |
White biotechnology for green chemistry: fermentative 2-oxocarboxylic acids as novel building blocks for subsequent chemical syntheses. | Journal of industrial microbiology & biotechnology 20051201 |
Pyruvate protects glucose-deprived Müller cells from nitric oxide-induced oxidative stress by radical scavenging. | Glia 20051201 |
In vivo carbon-13 magnetization transfer effect. Detection of aspartate aminotransferase reaction. | Magnetic resonance in medicine 20051201 |
Effect of aromatic ring-containing drugs on carnitine biosynthesis in rats with special regard to p-aminomethylbenzoic acid. | Metabolism: clinical and experimental 20051201 |
Electron cryotomography of the E. coli pyruvate and 2-oxoglutarate dehydrogenase complexes. | Structure (London, England : 1993) 20051201 |
alpha-Ketoglutarate (AKG) absorption from pig intestine and plasma pharmacokinetics. | Journal of animal physiology and animal nutrition 20051201 |
Enzyme inhibition assay for pyruvate dehydrogenase complex: clinical utility for the diagnosis of primary biliary cirrhosis. | World journal of gastroenterology 20051121 |
Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. | The Journal of biological chemistry 20051104 |
Alterations in neutrophil (PMN) free intracellular alpha-keto acid profiles and immune functions induced by L-alanyl-L-glutamine, arginine or taurine. | Amino acids 20051101 |
Mitochondrial succinate is instrumental for HIF1alpha nuclear translocation in SDHA-mutant fibroblasts under normoxic conditions. | Human molecular genetics 20051101 |
Effects of glucose limitation on biomass and spiramycin production by Streptomyces ambofaciens. | Bioprocess and biosystems engineering 20051101 |
Plasmodium falciparum possesses organelle-specific alpha-keto acid dehydrogenase complexes and lipoylation pathways. | Biochemical Society transactions 20051101 |
Determinants of substrate specificity in omega-aminotransferases. | The Journal of biological chemistry 20051028 |
Identification of PamA as a PII-binding membrane protein important in nitrogen-related and sugar-catabolic gene expression in Synechocystis sp. PCC 6803. | The Journal of biological chemistry 20051014 |
Efficacy of levo carnitine and alpha lipoic acid in ameliorating the decline in mitochondrial enzymes during aging. | Clinical nutrition (Edinburgh, Scotland) 20051001 |
Differential requirements of calcium for oxoglutarate dehydrogenase and mitochondrial nitric-oxide synthase under hypoxia: impact on the regulation of mitochondrial oxygen consumption. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20051001 |
Lysine is catabolized to 2-aminoadipic acid in Penicillium chrysogenum by an omega-aminotransferase and to saccharopine by a lysine 2-ketoglutarate reductase. Characterization of the omega-aminotransferase. | Molecular genetics and genomics : MGG 20051001 |
Localization of NAD-isocitrate dehydrogenase and glutamate dehydrogenase in rice roots: candidates for providing carbon skeletons to NADH-glutamate synthase. | Plant & cell physiology 20051001 |
Interleukin 4 and prolonged hypoxia induce a higher gene expression of lysyl hydroxylase 2 and an altered cross-link pattern: important pathogenetic steps in early and late stage of systemic scleroderma? | Matrix biology : journal of the International Society for Matrix Biology 20051001 |
Antioxidant effect of Sargassum polycystum (Phaeophyceae) against acetaminophen induced changes in hepatic mitochondrial enzymes during toxic hepatitis. | Chemosphere 20051001 |
Molecular properties and enhancement of thermostability by random mutagenesis of glutamate dehydrogenase from Bacillus subtilis. | Bioscience, biotechnology, and biochemistry 20051001 |
Resonance assignments of Escherichia coli AlkB: a key 2-oxoglutarate and Fe(II) dependent dioxygenase of the adaptive DNA-repair response. | Journal of biomolecular NMR 20051001 |
Modification of thiamine pyrophosphate dependent enzyme activity by oxythiamine in Saccharomyces cerevisiae cells. | Canadian journal of microbiology 20051001 |
Effects of alpha-ketoglutarate on bone homeostasis and plasma amino acids in turkeys. | Poultry science 20051001 |
Dual effect of pyruvate in isolated nerve terminals: generation of reactive oxygen species and protection of aconitase. | Neurochemical research 20051001 |
Hypoxia-inducible factor prolyl hydroxylase 2 has a high affinity for ferrous iron and 2-oxoglutarate. | Molecular bioSystems 20051001 |
Structural and functional changes in heart mitochondria from sucrose-fed hypertriglyceridemic rats. | Biochimica et biophysica acta 20050930 |
Incorporation of oxygen into the succinate co-product of iron(II) and 2-oxoglutarate dependent oxygenases from bacteria, plants and humans. | FEBS letters 20050926 |
Effect of sub-acute oral cyanide administration in rats: protective efficacy of alpha-ketoglutarate and sodium thiosulfate. | Chemico-biological interactions 20050910 |
Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. I. Kinetic studies. | The Journal of biological chemistry 20050909 |
Structural and mechanistic studies on anthocyanidin synthase catalysed oxidation of flavanone substrates: the effect of C-2 stereochemistry on product selectivity and mechanism. | Organic & biomolecular chemistry 20050907 |
Increasing mitochondrial substrate-level phosphorylation can rescue respiratory growth of an ATP synthase-deficient yeast. | The Journal of biological chemistry 20050902 |
Functional analysis of TMLH variants and definition of domains required for catalytic activity and mitochondrial targeting. | Journal of cellular physiology 20050901 |
Modulation of higher-plant NAD(H)-dependent glutamate dehydrogenase activity in transgenic tobacco via alteration of beta subunit levels. | Planta 20050901 |
Effect of L-carnitine on acetyl-CoA content and activity of blood platelets in healthy and diabetic persons. | Clinical chemistry 20050901 |
Evidence for carbon flux shortage and strong carbon/nitrogen interactions in pea nodules at early stages of water stress. | Journal of experimental botany 20050901 |
Mitochondria-driven changes in leaf NAD status exert a crucial influence on the control of nitrate assimilation and the integration of carbon and nitrogen metabolism. | Plant physiology 20050901 |
Tubulointerstitial nephritis and Fanconi syndrome in primary biliary cirrhosis. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20050901 |
Lipopolysaccharide induces cell death in cultured porcine myenteric neurons. | Digestive diseases and sciences 20050901 |
Alcoholic stem extract of Coscinium fenestratum regulates carbohydrate metabolism and improves antioxidant status in streptozotocin-nicotinamide induced diabetic rats. | Evidence-based complementary and alternative medicine : eCAM 20050901 |
Free CoA-mediated regulation of intermediary and central metabolism: an hypothesis which accounts for the excretion of alpha-ketoglutarate during aerobic growth of Escherichia coli on acetate. | Research in microbiology 20050901 |
Altering the substrate specificity of glutamate dehydrogenase from Bacillus subtilis by site-directed mutagenesis. | Bioscience, biotechnology, and biochemistry 20050901 |
Biochemical characterisation of some non fermenting, non arginine hydrolysing mycoplasmas of ruminants. | Veterinary microbiology 20050810 |
Phosphonate analogues of alpha-ketoglutarate inhibit the activity of the alpha-ketoglutarate dehydrogenase complex isolated from brain and in cultured cells. | Biochemistry 20050809 |
The N-terminal cleavable extension of plant carrier proteins is responsible for efficient insertion into the inner mitochondrial membrane. | Journal of molecular biology 20050805 |
Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice. | American journal of physiology. Endocrinology and metabolism 20050801 |
CaAlaAT1 catalyzes the alanine: 2-oxoglutarate aminotransferase reaction during the resistance response against Tobacco mosaic virus in hot pepper. | Planta 20050801 |
Nrf2 activation involves an oxidative-stress independent pathway in tetrafluoroethylcysteine-induced cytotoxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20050801 |
Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801 |
Multi-target antimicrobial actions of zinc against oral anaerobes. | Archives of oral biology 20050801 |
Mycobacterium tuberculosis appears to lack alpha-ketoglutarate dehydrogenase and encodes pyruvate dehydrogenase in widely separated genes. | Molecular microbiology 20050801 |
Assays for mechanistic investigations of protein/histone acetyltransferases. | Methods (San Diego, Calif.) 20050801 |
Thiamine-responsive congenital lactic acidosis: clinical and biochemical studies. | Pediatric neurology 20050801 |
Ornithine alpha-ketoglutarate metabolism in the healthy rat in the postabsorptive state. | Metabolism: clinical and experimental 20050801 |
HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. | Cancer cell 20050801 |
Effect of potassium salts in rats adapted to an acidogenic high-sulfur amino acid diet. | The British journal of nutrition 20050801 |
Gibberellin 2-oxidases from seedlings of adzuki bean (Vigna angularis) show high gibberellin-binding activity in the presence of 2-oxoglutarate and Co2+. | Bioscience, biotechnology, and biochemistry 20050801 |
Similarities and differences between the characteristics of gibberellin-binding protein and gibberellin 2-oxidases in adzuki bean (Vigna angularis) seedlings. | Bioscience, biotechnology, and biochemistry 20050801 |
A global survey of gene regulation during cold acclimation in Arabidopsis thaliana. | PLoS genetics 20050801 |
Disorders of pyruvate metabolism and the tricarboxylic acid cycle. | Molecular genetics and metabolism 20050801 |
Therapeutic effect of tamoxifen and energy-modulating vitamins on carbohydrate-metabolizing enzymes in breast cancer. | Cancer chemotherapy and pharmacology 20050701 |
Mg2+-malate co-transport, a mechanism for Na+-independent Mg2+ transport in neurons of the leech Hirudo medicinalis. | Journal of neurophysiology 20050701 |
Differential expression of procollagen lysine 2-oxoglutarate 5-deoxygenase and matrix metalloproteinase isoforms in hypothyroid rat ovary and disintegration of extracellular matrix. | Endocrinology 20050701 |
Cerebral metabolic disturbances in the brain during acute liver failure: from hyperammonemia to energy failure and proteolysis. | Neurochemistry international 20050701 |
A combined (1)H NMR and HPLC-MS-based metabonomic study of urine from obese (fa/fa) Zucker and normal Wistar-derived rats. | Journal of pharmaceutical and biomedical analysis 20050701 |
Zinc complexes with cyclic derivatives of alpha-ketoglutaric acid thiosemicarbazone: Synthesis, X-ray structures and DNA interactions. | Journal of inorganic biochemistry 20050701 |
Convergent evolution of hydroxylation mechanisms in the fungal kingdom: molybdenum cofactor-independent hydroxylation of xanthine via alpha-ketoglutarate-dependent dioxygenases. | Molecular microbiology 20050701 |
Identification of differentially expressed genes in hepatic HepG2 cells treated with acetaminophen using suppression subtractive hybridization. | Biological & pharmaceutical bulletin 20050701 |
Short-term regulation of the alpha-ketoglutarate dehydrogenase complex by energy-linked and some other effectors. | Biochemistry. Biokhimiia 20050701 |
Elevated formation of pyridinoline cross-links by profibrotic cytokines is associated with enhanced lysyl hydroxylase 2b levels. | Biochimica et biophysica acta 20050630 |
An NAD(+)-dependent glutamate dehydrogenase cloned from the ruminal ciliate protozoan, Entodinium caudatum. | FEMS microbiology letters 20050615 |
Bioenergetics in glutaryl-coenzyme A dehydrogenase deficiency: a role for glutaryl-coenzyme A. | The Journal of biological chemistry 20050610 |
Kinetic dissection of the catalytic mechanism of taurine:alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli. | Biochemistry 20050607 |
Does dietary ornithine alpha-ketoglutarate supplementation protect the liver against ischemia-reperfusion injury? | Clinical nutrition (Edinburgh, Scotland) 20050601 |
Minoxidil exerts different inhibitory effects on gene expression of lysyl hydroxylase 1, 2, and 3: implications for collagen cross-linking and treatment of fibrosis. | Matrix biology : journal of the International Society for Matrix Biology 20050601 |
Selective inhibition of factor inhibiting hypoxia-inducible factor. | Journal of the American Chemical Society 20050601 |
2-Oxoglutarate and the PII homologues NifI1 and NifI2 regulate nitrogenase activity in cell extracts of Methanococcus maripaludis. | Molecular microbiology 20050601 |
Pretreatment of starved rats with ornithine alpha-ketoglutarate: effects on hepatic mRNA levels and plasma concentrations of three liver-secreted proteins. | Nutrition (Burbank, Los Angeles County, Calif.) 20050601 |
Differential gene expression of collagen-binding small leucine-rich proteoglycans and lysyl hydroxylases, during mineralization by MC3T3-E1 cells cultured on titanium implant material. | European journal of oral sciences 20050601 |
[Construction of recombinant Escherichia coli strains producing poly (4-hydroxybutyric acid) homopolyester from glucose]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20050601 |
Methylophilus quaylei sp. nov., a new aerobic obligately methylotrophic bacterium. | Systematic and applied microbiology 20050601 |
Enhanced expression of a novel dioxygenase during the early developmental stage of tomato fruit. | Journal of plant physiology 20050601 |
Robustness of downhill folding: guidelines for the analysis of equilibrium folding experiments on small proteins. | Biochemistry 20050524 |
Dynamics of glutamate synthesis and excretion fluxes in batch and continuous cultures of temperature-triggered Corynebacterium glutamicum. | Bioprocess and biosystems engineering 20050501 |
Hepatic mitochondrial glutathione: transport and role in disease and toxicity. | Toxicology and applied pharmacology 20050501 |
Role of glutathione transport processes in kidney function. | Toxicology and applied pharmacology 20050501 |
Hypoxia-inducible factor-1 drives the motility of the erythroid progenitor cell line, UT-7/Epo, via autocrine motility factor. | Experimental hematology 20050501 |
Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. | Annals of neurology 20050501 |
A novel mutation in the lysyl hydroxylase 1 gene causes decreased lysyl hydroxylase activity in an Ehlers-Danlos VIA patient. | The Journal of investigative dermatology 20050501 |
Pyruvate administered after severe hypoglycemia reduces neuronal death and cognitive impairment. | Diabetes 20050501 |
Severe cognitive impairment correlates with higher cerebrospinal fluid levels of lactate and pyruvate in a canine model of senile dementia. | Progress in neuro-psychopharmacology & biological psychiatry 20050501 |
Ascorbate depletion: a critical step in nickel carcinogenesis? | Environmental health perspectives 20050501 |
Allosteric NADP-glutamate dehydrogenase from aspergilli: purification, characterization and implications for metabolic regulation at the carbon-nitrogen interface. | Microbiology (Reading, England) 20050501 |
Differential expression of cardiac muscle mitochondrial matrix proteins in broilers from ascites-resistant and susceptible lines. | Poultry science 20050501 |
Protective effect of alpha-keto-beta-methyl-n-valeric acid on BV-2 microglia under hypoxia or oxidative stress. | Annals of the New York Academy of Sciences 20050501 |
Investigations into biochemical changes of genetic hypertensive rats using 1H nuclear magnetic resonance-based metabonomics. | Hypertension research : official journal of the Japanese Society of Hypertension 20050501 |
[Proteomics analysis on stressed myocardium injury-related proteins]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20050501 |
Aconitase and ATP synthase are targets of malondialdehyde modification and undergo an age-related decrease in activity in mouse heart mitochondria. | Biochemical and biophysical research communications 20050429 |
Gene expression and characterization of two 2-oxoacid:ferredoxin oxidoreductases from Aeropyrum pernix K1. | FEBS letters 20050425 |
Vmax regulation through domain and subunit changes. The active form of phosphoglycerate dehydrogenase. | Biochemistry 20050419 |
D-3-Phosphoglycerate dehydrogenase from Mycobacterium tuberculosis is a link between the Escherichia coli and mammalian enzymes. | The Journal of biological chemistry 20050415 |
The Skp1 prolyl hydroxylase from Dictyostelium is related to the hypoxia-inducible factor-alpha class of animal prolyl 4-hydroxylases. | The Journal of biological chemistry 20050415 |
The unexpected structural role of glutamate synthase [4Fe-4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit. | Archives of biochemistry and biophysics 20050415 |
Oxidation by 2-oxoglutarate oxygenases: non-haem iron systems in catalysis and signalling. | Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20050415 |
Substrate specificity of the human renal sodium dicarboxylate cotransporter, hNaDC-3, under voltage-clamp conditions. | American journal of physiology. Renal physiology 20050401 |
New functions for parts of the Krebs cycle in procyclic Trypanosoma brucei, a cycle not operating as a cycle. | The Journal of biological chemistry 20050401 |
PII signal transduction proteins: sensors of alpha-ketoglutarate that regulate nitrogen metabolism. | Current opinion in microbiology 20050401 |
Protective effect of Premna tomentosa extract (L. verbanacae) on acetaminophen-induced mitochondrial dysfunction in rats. | Molecular and cellular biochemistry 20050401 |
Dynamics of intracellular metabolites of glycolysis and TCA cycle during cell-cycle-related oscillation in Saccharomyces cerevisiae. | Biotechnology and bioengineering 20050330 |
Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity. | The Journal of biological chemistry 20050325 |
The pathway for IRP2 degradation involving 2-oxoglutarate-dependent oxygenase(s) does not require the E3 ubiquitin ligase activity of pVHL. | Biochimica et biophysica acta 20050322 |
Steady-state and transient kinetic analyses of taurine/alpha-ketoglutarate dioxygenase: effects of oxygen concentration, alternative sulfonates, and active-site variants on the FeIV-oxo intermediate. | Biochemistry 20050315 |
Isolation and characterization of enzymes involved in lysine catabolism from sorghum seeds. | Journal of agricultural and food chemistry 20050309 |
Mutational analysis of the nucleotide-binding domain of the anti-activator NifL. | Journal of molecular biology 20050304 |
Anaerobic and aerobic enzyme activities in human skeletal muscle from children and adults. | Pediatric research 20050301 |
A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency. | Human mutation 20050301 |
Glutathione depletion resulting in selective mitochondrial complex I inhibition in dopaminergic cells is via an NO-mediated pathway not involving peroxynitrite: implications for Parkinson's disease. | Journal of neurochemistry 20050301 |
Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets. | Analytical chemistry 20050301 |
Unique mechanistic features of post-translational regulation of glutamine synthetase activity in Methanosarcina mazei strain Gö1 in response to nitrogen availability. | Molecular microbiology 20050301 |
Dissimilation of cysteate via 3-sulfolactate sulfo-lyase and a sulfate exporter in Paracoccus pantotrophus NKNCYSA. | Microbiology (Reading, England) 20050301 |
Comparative study of flux redistribution of metabolic pathway in glutamate production by two coryneform bacteria. | Metabolic engineering 20050301 |
Mitochondrial aging and dysfunction in Alzheimer's disease. | Progress in neuro-psychopharmacology & biological psychiatry 20050301 |
Chemopreventive effect of piperine on mitochondrial TCA cycle and phase-I and glutathione-metabolizing enzymes in benzo(a)pyrene induced lung carcinogenesis in Swiss albino mice. | Molecular and cellular biochemistry 20050301 |
Teaching about citric acid cycle using plant mitochondrial preparations: Some assays for use in laboratory courses*. | Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 20050301 |
Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes. | Molecules and cells 20050227 |
Succinate complex crystal structures of the alpha-ketoglutarate-dependent dioxygenase AtsK: steric aspects of enzyme self-hydroxylation. | The Journal of biological chemistry 20050218 |
Regulation of nif expression in Methanococcus maripaludis: roles of the euryarchaeal repressor NrpR, 2-oxoglutarate, and two operators. | The Journal of biological chemistry 20050218 |
Kinetic properties and metabolic contributions of yeast mitochondrial and cytosolic NADP+-specific isocitrate dehydrogenases. | The Journal of biological chemistry 20050211 |
Aluminum triggers decreased aconitase activity via Fe-S cluster disruption and the overexpression of isocitrate dehydrogenase and isocitrate lyase: a metabolic network mediating cellular survival. | The Journal of biological chemistry 20050204 |
Mutations in the D-2-hydroxyglutarate dehydrogenase gene cause D-2-hydroxyglutaric aciduria. | American journal of human genetics 20050201 |
Fatty acid synthesis and the oxidative pentose phosphate pathway in developing embryos of oilseed rape (Brassica napus L.). | Journal of experimental botany 20050201 |
Nitrogen fixation: key genetic regulatory mechanisms. | Biochemical Society transactions 20050201 |
Nitrogen assimilation and nitrogen control in cyanobacteria. | Biochemical Society transactions 20050201 |
Monochloroacetic acid inhibits liver gluconeogenesis by inactivating glyceraldehyde-3-phosphate dehydrogenase. | Chemical research in toxicology 20050201 |
Inhibition by N'-nitrosonornicotine of the catalytic activity of glutamate dehydrogenase in alpha-ketoglutarate amination. | Journal of enzyme inhibition and medicinal chemistry 20050201 |
Krebs cycle intermediates modulate thiobarbituric acid reactive species (TBARS) production in rat brain in vitro. | Neurochemical research 20050201 |
Aerobic organic carbon mineralization by sulfate-reducing bacteria in the oxygen-saturated photic zone of a hypersaline microbial mat. | Microbial ecology 20050201 |
Isocitrate dehydrogenase from the hyperthermophile Aeropyrum pernix: X-ray structure analysis of a ternary enzyme-substrate complex and thermal stability. | Journal of molecular biology 20050121 |
Characterization of a second Arabidopsis thaliana prolyl 4-hydroxylase with distinct substrate specificity. | The Journal of biological chemistry 20050114 |
Evaluation of brain mitochondrial glutamate and alpha-ketoglutarate transport under physiologic conditions. | Journal of neuroscience research 20050101 |
4-Hydroxyphenylpyruvate dioxygenase. | Archives of biochemistry and biophysics 20050101 |
Structure--function studies on the iron-sulfur flavoenzyme glutamate synthase: an unexpectedly complex self-regulated enzyme. | Archives of biochemistry and biophysics 20050101 |
A fluorescence-based assay for 2-oxoglutarate-dependent oxygenases. | Analytical biochemistry 20050101 |
Perspective: emerging evidence for signaling roles of mitochondrial anaplerotic products in insulin secretion. | American journal of physiology. Endocrinology and metabolism 20050101 |
Reversal by aminoguanidine of the age-related increase in glycoxidation and lipoxidation in the cardiovascular system of Fischer 344 rats. | Biochemical pharmacology 20050101 |
BCL-xL overexpression effectively protects against tetrafluoroethylcysteine-induced intramitochondrial damage and cell death. | Biochemical pharmacology 20050101 |
The genome sequence of the ethanologenic bacterium Zymomonas mobilis ZM4. | Nature biotechnology 20050101 |
The human malaria parasite Plasmodium falciparum possesses two distinct dihydrolipoamide dehydrogenases. | Molecular microbiology 20050101 |
Overexpression of lysyl hydroxylase-2b leads to defective collagen fibrillogenesis and matrix mineralization. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050101 |
Bioinformatic mapping of AlkB homology domains in viruses. | BMC genomics 20050101 |
Disruption of MRG19 results in altered nitrogen metabolic status and defective pseudohyphal development in Saccharomyces cerevisiae. | Microbiology (Reading, England) 20050101 |
Structural basis for stereo-specific catalysis in NAD(+)-dependent (R)-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans. | The FEBS journal 20050101 |
Cyclic nucleotide binding proteins in the Arabidopsis thaliana and Oryza sativa genomes. | BMC bioinformatics 20050101 |
Inhibition of the alpha-ketoglutarate dehydrogenase complex by the myeloperoxidase products, hypochlorous acid and mono-N-chloramine. | Journal of neurochemistry 20050101 |
Hesperidin, a citrus bioflavonoid, decreases the oxidative stress produced by carbon tetrachloride in rat liver and kidney. | BMC pharmacology 20050101 |
Reactive oxygen species production in the mitochondrial matrix: implications for the mechanism of mitochondrial mutation accumulation. | Rejuvenation research 20050101 |
Supplementation of L-carnitine improves mitochondrial enzymes in heart and skeletal muscle of aged rats. | Experimental aging research 20050101 |
Dual substrate recognition of aminotransferases. | Chemical record (New York, N.Y.) 20050101 |
Proteome analysis of a recombinant Bacillus megaterium strain during heterologous production of a glucosyltransferase. | Proteome science 20050101 |
Role of mitochondrial dysfunction and oxidative stress in the pathogenesis of selective neuronal loss in Wernicke's encephalopathy. | Molecular neurobiology 20050101 |
The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration. | Molecular neurobiology 20050101 |
Mutation analysis of the PLOD1 gene: an efficient multistep approach to the molecular diagnosis of the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VIA). | Molecular genetics and metabolism 20050101 |
Modeling Lactococcus lactis using a genome-scale flux model. | BMC microbiology 20050101 |
Clonogenic growth of human breast cancer cells co-cultured in direct contact with serum-activated fibroblasts. | Breast cancer research : BCR 20050101 |
Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene. | Journal of biomedicine & biotechnology 20050101 |
Protective effect of bacoside A on cigarette smoking-induced brain mitochondrial dysfunction in rats. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20050101 |
Solution structure of the fifth and sixth transmembrane segments of the mitochondrial oxoglutarate carrier. | Molecular membrane biology 20050101 |
Production of reactive oxygen species in brain mitochondria: contribution by electron transport chain and non-electron transport chain sources. | Antioxidants & redox signaling 20050101 |
[Carbon metabolism of filamentous anoxygenic phototrophic bacteria of the family Oscillochloridaceae]. | Mikrobiologiia 20050101 |
Sequence-based discovery of the human and rodent peroxisomal proteome. | Applied bioinformatics 20050101 |
Ammonium assimilation in cyanobacteria. | Photosynthesis research 20050101 |
Glutamate synthase: structural, mechanistic and regulatory properties, and role in the amino acid metabolism. | Photosynthesis research 20050101 |
[Dynamics of the reversible transition of Vibrio cholerae into the uncultivable state in the presence of organic and inorganic microcosmic components]. | Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20050101 |
Fumarase deficiency presenting with periventricular cysts. | Journal of inherited metabolic disease 20050101 |
An Ehlers-Danlos syndrome type VIA patient with cystic malformations of the meninges. | European journal of dermatology : EJD 20050101 |
Purification and kinetic studies of recombinant gibberellin dioxygenases. | BMC plant biology 20050101 |
[The modification of nitric oxide production by exogenous substrates of Krebs cycle during acute hypoxia]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101 |
Natural history of S-adenosylmethionine-binding proteins. | BMC structural biology 20050101 |
Characterization of the metabolic shift between oxidative and fermentative growth in Saccharomyces cerevisiae by comparative 13C flux analysis. | Microbial cell factories 20050101 |
Metabolic profiling of laser microdissected vascular bundles of Arabidopsis thaliana. | Plant methods 20050101 |
Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis. | Critical care (London, England) 20050101 |
Role of cultivation media in the development of yeast strains for large scale industrial use. | Microbial cell factories 20050101 |
Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers. | BMC biochemistry 20050101 |
Assessing the precision of high-throughput computational and laboratory approaches for the genome-wide identification of protein subcellular localization in bacteria. | BMC genomics 20050101 |
Substrate-induced conformational changes of the mitochondrial oxoglutarate carrier: a spectroscopic and molecular modelling study. | Molecular membrane biology 20050101 |
Bacterial genome adaptation to niches: divergence of the potential virulence genes in three Burkholderia species of different survival strategies. | BMC genomics 20050101 |
Kinetic characterization of human hydroxyacid-oxoacid transhydrogenase: relevance to D-2-hydroxyglutaric and gamma-hydroxybutyric acidurias. | Journal of inherited metabolic disease 20050101 |
[Effect of intermittent hypoxic hypoxia on energy supply of rat skeletal muscle during adaptation to physical load]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20050101 |
L-Arabinose 1-dehydrogenase: a novel enzyme involving in bacterial L-arabinose metabolism. | Nucleic acids symposium series (2004) 20050101 |
Many amino acid substitutions in a hypoxia-inducible transcription factor (HIF)-1alpha-like peptide cause only minor changes in its hydroxylation by the HIF prolyl 4-hydroxylases: substitution of 3,4-dehydroproline or azetidine-2-carboxylic acid for the proline leads to a high rate of uncoupled 2-oxoglutarate decarboxylation. | The Journal of biological chemistry 20041231 |
Complex formation and catalytic activation by the PII signaling protein of N-acetyl-L-glutamate kinase from Synechococcus elongatus strain PCC 7942. | The Journal of biological chemistry 20041231 |
Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli. | Journal of the American Chemical Society 20041229 |
Regulation of 2-oxoglutarate (alpha-ketoglutarate) dehydrogenase stability by the RING finger ubiquitin ligase Siah. | The Journal of biological chemistry 20041217 |
Mitochondria/nuclear signaling of alternative oxidase gene expression occurs through distinct pathways involving organic acids and reactive oxygen species. | Plant cell reports 20041201 |
Tricarboxylic acid cycle enzymes following thiamine deficiency. | Neurochemistry international 20041201 |
Proteomic identification of collagens and related proteins in human fibroblasts. | Amino acids 20041201 |
Factor inhibiting hypoxia-inducible factor (FIH) and other asparaginyl hydroxylases. | Biochemical Society transactions 20041201 |
Phenotypic and molecular characterization of Bruck syndrome (osteogenesis imperfecta with contractures of the large joints) caused by a recessive mutation in PLOD2. | American journal of medical genetics. Part A 20041201 |
Heterogeneous basis of the type VIB form of Ehlers-Danlos syndrome (EDS VIB) that is unrelated to decreased collagen lysyl hydroxylation. | American journal of medical genetics. Part A 20041201 |
Effects of ornithine on neutrophil (PMN) free amino acid and alpha-keto acid profiles and immune functions in vitro. | Amino acids 20041201 |
Glutamate dehydrogenase of tobacco is mainly induced in the cytosol of phloem companion cells when ammonia is provided either externally or released during photorespiration. | Plant physiology 20041201 |
Decreased expression of lysyl hydroxylase 2 (LH2) in skin fibroblasts from three Ehlers-Danlos patients does not result from mutations in either the coding or proximal promoter region of the LH2 gene. | Molecular genetics and metabolism 20041201 |
Insertion of transposon Tn5tac1 in the Sinorhizobium meliloti malate dehydrogenase (mdh) gene results in conditional polar effects on downstream TCA cycle genes. | Molecular plant-microbe interactions : MPMI 20041201 |
Effect of alpha-ketoglutarate against selenite cataract formation. | Experimental eye research 20041201 |
Interaction of N-acetylglutamate kinase with a PII-like protein in rice. | Plant & cell physiology 20041201 |
Isolation and characterization of cytosolic alanine aminotransferase isoforms from starved rat liver. | Molecular and cellular biochemistry 20041201 |
Regulation by magnesium of potato tuber mitochondrial respiratory activities. | Journal of bioenergetics and biomembranes 20041201 |
The fate of P2Y-related orphan receptors: GPR80/99 and GPR91 are receptors of dicarboxylic acids. | Purinergic signalling 20041201 |
GPR80/99, proposed to be the P2Y(15) receptor activated by adenosine and AMP, is not a P2Y receptor. | Purinergic signalling 20041201 |
Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation. | Biochemistry 20041116 |
Association of the dihydrolipoamide dehydrogenase gene with Alzheimer's disease in an Ashkenazi Jewish population. | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20041115 |
Disruption of dimerization and substrate phosphorylation inhibit factor inhibiting hypoxia-inducible factor (FIH) activity. | The Biochemical journal 20041101 |
Anaplerotic input is sufficient to induce time-dependent potentiation of insulin release in rat pancreatic islets. | American journal of physiology. Endocrinology and metabolism 20041101 |
Molecular dynamics simulation of the interaction between the complex iron-sulfur flavoprotein glutamate synthase and its substrates. | Protein science : a publication of the Protein Society 20041101 |
Copper(II) complexes with substituted thiosemicarbazones of alpha-ketoglutaric acid: synthesis, X-ray structures, DNA binding studies, and nuclease and biological activity. | Inorganic chemistry 20041101 |
Inhibition of cardiac mitochondrial respiration by salicylic acid and acetylsalicylate. | Journal of cardiovascular pharmacology 20041101 |
Gender-specific proteomic alterations in glycolytic and mitochondrial pathways in aging monkey hearts. | Journal of molecular and cellular cardiology 20041101 |
Effect of low- and high-intensity pulsed ultrasound on collagen post-translational modifications in MC3T3-E1 osteoblasts. | Calcified tissue international 20041101 |
Amino acid transamination in permeabilised cells of Lactobacillus helveticus, Lb. paracasei and Lb. danicus. | The Journal of dairy research 20041101 |
H2S cytotoxicity mechanism involves reactive oxygen species formation and mitochondrial depolarisation. | Toxicology 20041015 |
A mechanism of sulfite neurotoxicity: direct inhibition of glutamate dehydrogenase. | The Journal of biological chemistry 20041008 |
Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. | The Journal of biological chemistry 20041008 |
Conformational flexibility of the C terminus with implications for substrate binding and catalysis revealed in a new crystal form of deacetoxycephalosporin C synthase. | Journal of molecular biology 20041008 |
Comparison of ion-pair chromatography and capillary zone electrophoresis for the assay of organic acids as markers of abnormal metabolism. | Journal of chromatography. A 20041008 |
Intermediates of Krebs cycle correct the depression of the whole body oxygen consumption and lethal cooling in barbiturate poisoning in rat. | Toxicology 20041001 |
Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath). | PLoS biology 20041001 |
Identification of distinct genes with restricted expression in the somitic mesoderm in Xenopus embryo. | Gene expression patterns : GEP 20041001 |
Metabolic flux analysis for calcium dependent antibiotic (CDA) production in Streptomyces coelicolor. | Metabolic engineering 20041001 |
Dose dependency of the effect of ornithine alpha-ketoglutarate on tissue glutamine concentrations and hypercatabolic response in endotoxaemic rats. | The British journal of nutrition 20041001 |
Effect of ascorbate, nitrate and nitrite on the amount of flavour compounds produced from leucine by Staphylococcus xylosus and Staphylococcus carnosus. | Meat science 20041001 |
Branched-chain amino acids and neurotransmitter metabolism: expression of cytosolic branched-chain aminotransferase (BCATc) in the cerebellum and hippocampus. | The Journal of comparative neurology 20040927 |
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress. | The Journal of biological chemistry 20040924 |
Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. | Biochemistry 20040921 |
Distinct intracellular localization of Gpd1p and Gpd2p, the two yeast isoforms of NAD+-dependent glycerol-3-phosphate dehydrogenase, explains their different contributions to redox-driven glycerol production. | The Journal of biological chemistry 20040917 |
Generation of reactive oxygen species in the reaction catalyzed by alpha-ketoglutarate dehydrogenase. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908 |
Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908 |
Characterization of collagenous peptides bound to lysyl hydroxylase isoforms. | The Journal of biological chemistry 20040903 |
Urease-glutamic dehydrogenase biosensor for screening heavy metals in water and soil samples. | Analytical and bioanalytical chemistry 20040901 |
The oxo/peroxo debate: a nonheme iron perspective. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20040901 |
Glutamatergic neurotransmission and neuronal glucose oxidation are coupled during intense neuronal activation. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040901 |
PCR method based on the ogdH gene for the detection of Salmonella spp. from chicken meat samples. | Journal of microbiology (Seoul, Korea) 20040901 |
Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria--case studies. | Mitochondrion 20040901 |
Structures of human cytosolic NADP-dependent isocitrate dehydrogenase reveal a novel self-regulatory mechanism of activity. | The Journal of biological chemistry 20040806 |
Interaction of L-glutamate oxidase with triazine dyes: selection of ligands for affinity chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040805 |
Regulation of transcription and activity of Rhizobium etli glutaminase A. | Biochimica et biophysica acta 20040804 |
Lysyl hydroxylase-2b directs collagen cross-linking pathways in MC3T3-E1 cells. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040801 |
Flux to acetate and lactate excretions in industrial fermentations: physiological and biochemical implications. | Journal of industrial microbiology & biotechnology 20040801 |
Krebs cycle enzymes from livers of old mice are differentially regulated by caloric restriction. | Experimental gerontology 20040801 |
Ornithine alpha-ketoglutarate supplementation influences motor activity in healthy rats. | Clinical nutrition (Edinburgh, Scotland) 20040801 |
Cellular oxygen sensing need in CNS function: physiological and pathological implications. | The Journal of experimental biology 20040801 |
Mitochondrial enzymes and endoplasmic reticulum calcium stores as targets of oxidative stress in neurodegenerative diseases. | Journal of bioenergetics and biomembranes 20040801 |
Molecular biology of erythropoietin. | Internal medicine (Tokyo, Japan) 20040801 |
Addition of α-ketoglutarate enhances formation of volatiles by Staphylococcus carnosus during sausage fermentation. | Meat science 20040801 |
Identification of a dehydrogenase acting on D-2-hydroxyglutarate. | The Biochemical journal 20040701 |
Molecular and biochemical characterization of D-phosphoglycerate dehydrogenase from Entamoeba histolytica. A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways. | European journal of biochemistry 20040701 |
Alpha-ketoglutarate treatment early in postnatal life improves bone density in lambs at slaughter. | Bone 20040701 |
Increased formation of pyridinoline cross-links due to higher telopeptide lysyl hydroxylase levels is a general fibrotic phenomenon. | Matrix biology : journal of the International Society for Matrix Biology 20040701 |
Glutamic acid removal and PHB storage in the activated sludge process under dynamic conditions. | Biotechnology and bioengineering 20040630 |
Inhibitory effects of Cimicifuga heracleifolia extract on glutamate formation and glutamate dehydrogenase activity in cultured islets. | Molecules and cells 20040630 |
Immunochemical identification of coenzyme Q0-dihydrolipoamide adducts in the E2 components of the alpha-ketoglutarate and pyruvate dehydrogenase complexes partially explains the cellular toxicity of coenzyme Q0. | The Journal of biological chemistry 20040625 |
Inhibition of thiamin diphosphate dependent enzymes by 3-deazathiamin diphosphate. | Organic & biomolecular chemistry 20040621 |
Limited transfer of cytosolic NADH into mitochondria at high cardiac workload. | American journal of physiology. Heart and circulatory physiology 20040601 |
Endogenous 2-oxoacids differentially regulate expression of oxygen sensors. | The Biochemical journal 20040601 |
Respective roles of the glutamine synthetase/glutamate synthase cycle and glutamate dehydrogenase in ammonium and amino acid metabolism during germination and post-germinative growth in the model legume Medicago truncatula. | Planta 20040601 |
The role of glutamine transaminase K (GTK) in sulfur and alpha-keto acid metabolism in the brain, and in the possible bioactivation of neurotoxicants. | Neurochemistry international 20040601 |
A metabonomic investigation of the biochemical effects of mercuric chloride in the rat using 1H NMR and HPLC-TOF/MS: time dependent changes in the urinary profile of endogenous metabolites as a result of nephrotoxicity. | The Analyst 20040601 |
The potential biological mechanisms of arsenic-induced diabetes mellitus. | Toxicology and applied pharmacology 20040601 |
The Synechococcus elongatus P signal transduction protein controls arginine synthesis by complex formation with N-acetyl-L-glutamate kinase. | Molecular microbiology 20040601 |
L-ornithine alpha-ketoglutarate in HIV infection: effects on muscle, gastrointestinal, and immune functions. | Nutrition (Burbank, Los Angeles County, Calif.) 20040601 |
Role of the amino-terminal GAF domain of the NifA activator in controlling the response to the antiactivator protein NifL. | Molecular microbiology 20040601 |
Absorption of alpha-ketoglutarate by the gastrointestinal tract of pigs. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040601 |
Upregulation of the mitochondrial phosphate carrier during freezing in the wood frog Rana sylvatica: potential roles of transporters in freeze tolerance. | Journal of bioenergetics and biomembranes 20040601 |
Global carbon/nitrogen control by PII signal transduction in cyanobacteria: from signals to targets. | FEMS microbiology reviews 20040601 |
A challenge for 21st century molecular biology and biochemistry: what are the causes of obligate autotrophy and methanotrophy? | FEMS microbiology reviews 20040601 |
Regulation of cellular plasticity and resilience by mood stabilizers: the role of AMPA receptor trafficking. | Dialogues in clinical neuroscience 20040601 |
[DOOR (deafness, onychodystrophy, osteodystrophy, mental retardation) syndrome]. | Orvosi hetilap 20040530 |
Prolyl 3-hydroxylase 1, enzyme characterization and identification of a novel family of enzymes. | The Journal of biological chemistry 20040528 |
3-Isopropylmalate is the major endogenous substrate of the Saccharomyces cerevisiae trans-aconitate methyltransferase. | Biochemistry 20040525 |
A hybrid density functional study of O-O bond cleavage and phenyl ring hydroxylation for a biomimetic non-heme iron complex. | Inorganic chemistry 20040517 |
Structural studies of the catalytic reaction pathway of a hyperthermophilic histidinol-phosphate aminotransferase. | The Journal of biological chemistry 20040514 |
Physiology: orphan detectors of metabolism. | Nature 20040513 |
Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors. | Nature 20040513 |
Conversion into GABA (gamma-aminobutyric acid) may reduce the capacity of L-glutamine as an insulin secretagogue. | The Biochemical journal 20040501 |
Oxygen sensing by HIF hydroxylases. | Nature reviews. Molecular cell biology 20040501 |
Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo. | Annals of neurology 20040501 |
Aberrant activity of the DNA repair enzyme AlkB. | Journal of inorganic biochemistry 20040501 |
Collagen prolyl 4-hydroxylase tetramers and dimers show identical decreases in Km values for peptide substrates with increasing chain length: mutation of one of the two catalytic sites in the tetramer inactivates the enzyme by more than half. | The Journal of biological chemistry 20040430 |
The first biosynthetic studies of the azinomycins: acetate incorporation into azinomycin B. | Chemical communications (Cambridge, England) 20040421 |
Preservation of complex I function during hypoxia-reoxygenation-induced mitochondrial injury in proximal tubules. | American journal of physiology. Renal physiology 20040401 |
Hyperinsulinism/hyperammonemia syndrome: insights into the regulatory role of glutamate dehydrogenase in ammonia metabolism. | Molecular genetics and metabolism 20040401 |
Ammonia toxicity to the brain and creatine. | Molecular genetics and metabolism 20040401 |
Inhibition of chlorophyll biosynthesis by mercury in excised etiolated maize leaf segments during greening: effect of 2-oxoglutarate. | Indian journal of experimental biology 20040401 |
Flavonoid methylation: a novel 4'-O-methyltransferase from Catharanthus roseus, and evidence that partially methylated flavanones are substrates of four different flavonoid dioxygenases. | Phytochemistry 20040401 |
[Effects of ovarian stimulation on serum concentrations of lipids and ketone bodies in patients undergoing IVF/ICSI treatment]. | Zentralblatt fur Gynakologie 20040401 |
Crystal structure of the alkylsulfatase AtsK: insights into the catalytic mechanism of the Fe(II) alpha-ketoglutarate-dependent dioxygenase superfamily. | Biochemistry 20040323 |
Mental retardation and hypotonia seen in the knock out mouse for Canavan disease is not due to succinate semialdehyde dehydrogenase deficiency. | Neuroscience letters 20040318 |
Functional features and genomic organization of mouse NaCT, a sodium-coupled transporter for tricarboxylic acid cycle intermediates. | The Biochemical journal 20040315 |
Influence of compartmental localization on the function of yeast NADP+-specific isocitrate dehydrogenases. | Archives of biochemistry and biophysics 20040315 |
Catalytic properties of the asparaginyl hydroxylase (FIH) in the oxygen sensing pathway are distinct from those of its prolyl 4-hydroxylases. | The Journal of biological chemistry 20040312 |
Role of iron (II)-2-oxoglutarate-dependent dioxygenases in the generation of hypoxia-induced phosphatidic acid through HIF-1/2 and von Hippel-Lindau-independent mechanisms. | The Journal of biological chemistry 20040305 |
Expression, purification, crystallization, and preliminary X-ray analysis of the N-terminal domain of Escherichia coli adenylyl transferase. | Protein expression and purification 20040301 |
Directed evolution relieves product inhibition and confers in vivo function to a rationally designed tyrosine aminotransferase. | Protein science : a publication of the Protein Society 20040301 |
Urinary alpha-ketoglutarate is elevated in patients with hyperinsulinism-hyperammonemia syndrome. | Clinica chimica acta; international journal of clinical chemistry 20040301 |
Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity. | Journal of neurochemistry 20040301 |
Regulation and differential expression of gdhA encoding NADP-specific glutamate dehydrogenase in Neisseria meningitidis clinical isolates. | Molecular microbiology 20040301 |
Production and export of metabolites from liver and heart mitochondria and anaplerosis. | Molecular and cellular biochemistry 20040301 |
Initiation of neuronal damage by complex I deficiency and oxidative stress in Parkinson's disease. | Neurochemical research 20040301 |
Substantial linkage disequilibrium across the dihydrolipoyl succinyltransferase gene region without Alzheimer's disease association. | Neurochemical research 20040301 |
Glutamate synthase: a fascinating pathway from L-glutamine to L-glutamate. | Cellular and molecular life sciences : CMLS 20040301 |
Mechanism of dioxygen activation in 2-oxoglutarate-dependent enzymes: a hybrid DFT study. | Chemistry (Weinheim an der Bergstrasse, Germany) 20040220 |
The SLC22 drug transporter family. | Pflugers Archiv : European journal of physiology 20040201 |
Overexpression of constitutively activated glutamate dehydrogenase induces insulin secretion through enhanced glutamate oxidation. | American journal of physiology. Endocrinology and metabolism 20040201 |
Endogenous mitochondrial oxidative stress: neurodegeneration, proteomic analysis, specific respiratory chain defects, and efficacious antioxidant therapy in superoxide dismutase 2 null mice. | Journal of neurochemistry 20040201 |
A novel biotin protein required for reductive carboxylation of 2-oxoglutarate by isocitrate dehydrogenase in Hydrogenobacter thermophilus TK-6. | Molecular microbiology 20040201 |
Retinal function loss after monocarboxylate transport inhibition. | Investigative ophthalmology & visual science 20040201 |
Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis. | Plant physiology 20040201 |
A role for the 2-oxoglutarate carrier in glutathione transport into hepatocyte mitochondria? | Hepatology (Baltimore, Md.) 20040201 |
Differentiation of dicarboxylate transporters in mesophyll and bundle sheath chloroplasts of maize. | Plant & cell physiology 20040201 |
Purification and properties of cytosolic alanine aminotransferase from the liver of two freshwater fish, Clarias batrachus and Labeo rohita. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040201 |
Metal-induced stabilization of trypsin modified with alpha-oxoglutaric acid. | Biotechnology letters 20040201 |
Mechanistic studies on three 2-oxoglutarate-dependent oxygenases of flavonoid biosynthesis: anthocyanidin synthase, flavonol synthase, and flavanone 3beta-hydroxylase. | The Journal of biological chemistry 20040109 |
Regulation of sodium-dicarboxylate cotransporter-3 from winter flounder kidney by protein kinase C. | American journal of physiology. Renal physiology 20040101 |
In situ evidence of an alternative oxidase and an uncoupling protein in the respiratory chain of Aspergillus fumigatus. | The international journal of biochemistry & cell biology 20040101 |
Brittle cornea syndrome and its delineation from the kyphoscoliotic type of Ehlers-Danlos syndrome (EDS VI): report on 23 patients and review of the literature. | American journal of medical genetics. Part A 20040101 |
In vitro uridylylation of the Azospirillum brasilense N-signal transducing GlnZ protein. | Protein expression and purification 20040101 |
The structural basis of cephalosporin formation in a mononuclear ferrous enzyme. | Nature structural & molecular biology 20040101 |
Value of energy substrates in HTK and UW to protect human liver endothelial cells against ischemia and reperfusion injury. | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20040101 |
A critical perspective of the use of (13)C-isotopomer analysis by GCMS and NMR as applied to cardiac metabolism. | Metabolic engineering 20040101 |
Purification and characterization of a branched-chain amino acid aminotransferase from Lactobacillus paracasei subsp. paracasei CHCC 2115. | Journal of applied microbiology 20040101 |
Factorial analysis of tricarboxylic acid cycle intermediates for optimization of zeaxanthin production from Flavobacterium multivorum. | Journal of applied microbiology 20040101 |
Creatine transporters: a reappraisal. | Molecular and cellular biochemistry 20040101 |
Inhibition of Krebs cycle and activation of glyoxylate cycle in the course of chronological aging of Saccharomyces cerevisiae. Compensatory role of succinate oxidation. | Biochimie 20040101 |
Amino-acid-dependent, differential effects of ethanol on glucose production in rabbit kidney-cortex tubules. | Alcohol and alcoholism (Oxford, Oxfordshire) 20040101 |
Entamoeba histolytica: kinetic and molecular evidence of a previously unidentified pyruvate kinase. | Experimental parasitology 20040101 |
Hypoxia and hypoxia inducible factors (HIF) as important regulators of tumor physiology. | Cancer treatment and research 20040101 |
NADP-glutamate dehydrogenase activity is increased under hyperosmotic conditions in the halotolerant yeast Debaryomyces hansenii. | Current microbiology 20040101 |
Modulating the hypoxia-inducible factor signaling pathway: applications from cardiovascular disease to cancer. | Current pharmaceutical design 20040101 |
Catabolism of leucine to branched-chain fatty acids in Staphylococcus xylosus. | Journal of applied microbiology 20040101 |
The possibility of involvement of the pools of alpha-ketoglutaric acid in the biosynthesis of carotenoids in chloroplasts. | Doklady. Biochemistry and biophysics 20040101 |
FeII/alpha-ketoglutarate-dependent hydroxylases and related enzymes. | Critical reviews in biochemistry and molecular biology 20040101 |
Transcriptional regulation of protein complexes in yeast. | Genome biology 20040101 |
Intracellular metabolic compartmentation assessed by 13C magnetic resonance spectroscopy. | Neurochemistry international 20040101 |
Serial 13C-based flux analysis of an L-phenylalanine-producing E. coli strain using the sensor reactor. | Biotechnology progress 20040101 |
[Levels of unified metabolites and thyroid hormones in blood and oral fluid of children with minimal brain dysfunction]. | Biomeditsinskaia khimiia 20040101 |
The phosphatidylserine receptor from Hydra is a nuclear protein with potential Fe(II) dependent oxygenase activity. | BMC cell biology 20040101 |
Alpha-Ketoglutarate dehydrogenase and lipoic acid synthase are important for the functioning of peroxisomes of Saccharomyces cerevisiae. | Cellular & molecular biology letters 20040101 |
The effect of alpha-ketoglutaric acid on amino acid utilization by nonstarter Lactobacillus spp. isolated from Cheddar cheese. | Letters in applied microbiology 20040101 |
[Etiology and pathogenesis of Parkinson's disease: from mitochondrial dysfunctions to familial Parkinson's disease]. | Rinsho shinkeigaku = Clinical neurology 20040101 |
The pattern and kinetics of substrate metabolism of Campylobacter jejuni and Campylobacter coli. | Letters in applied microbiology 20040101 |
Interactions of benzylpenicillin and non-steroidal anti-inflammatory drugs with the sodium-dependent dicarboxylate transporter NaDC-3. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20040101 |
RNA-binding proteins to assess gene expression states of co-cultivated cells in response to tumor cells. | Molecular cancer 20040101 |
Mitochondrial enzymes in schizophrenia. | Journal of molecular neuroscience : MN 20040101 |
Branched-chain amino acid aminotransferase and methionine formation in Mycobacterium tuberculosis. | BMC microbiology 20040101 |
Solution structure of the first and second transmembrane segments of the mitochondrial oxoglutarate carrier. | Molecular membrane biology 20040101 |
[New thermophilic methanotrophs of the genus Methylocaldum]. | Mikrobiologiia 20040101 |
Age-dependent alterations in mitochondrial enzymes in cortex, striatum and hippocampus of rat brain -- potential role of L-Carnitine. | Biogerontology 20040101 |
Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts. | Respiratory research 20040101 |
Molecular characterization and functional expression of flavonol 6-hydroxylase. | BMC plant biology 20040101 |
Hierarchical structure and modules in the Escherichia coli transcriptional regulatory network revealed by a new top-down approach. | BMC bioinformatics 20040101 |
[Effect of K-ATP channel opener-pinacidil on the liver mitochondria function in rats with different resistance to hypoxia during stress]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101 |
[Myocardium mitochondria functional state during adaptation to intermittent hypoxia and treatment with L-arginine]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101 |
Use of Lactococcus lactis subsp. cremoris NCDO 763 and α-ketoglutarate to improve the sensory quality of dry fermented sausages. | Meat science 20040101 |
Exploring the overproduction of amino acids using the bilevel optimization framework OptKnock. | Biotechnology and bioengineering 20031230 |
The molecular and cellular physiology of basolateral organic anion transport in mammalian renal tubules. | Biochimica et biophysica acta 20031230 |
L-carnitine ameliorates abnormal vulnerability of steatotic rat livers to cold ischemic preservation. | Transplantation 20031227 |
Synthesis of (3S,5R)-carbapenam-3-carboxylic acid and its role in carbapenem biosynthesis and the stereoinversion problem. | Journal of the American Chemical Society 20031224 |
Impaired oxidative phosphorylation in hepatic mitochondria in growth-retarded rats. | American journal of physiology. Endocrinology and metabolism 20031201 |
Phylogeny of the bacterial superfamily of Crp-Fnr transcription regulators: exploiting the metabolic spectrum by controlling alternative gene programs. | FEMS microbiology reviews 20031201 |
Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel. | Molecular pharmacology 20031201 |
Heterocyst development in Anabaena. | Current opinion in microbiology 20031201 |
Substrate specificity of glutaminyl cyclases from plants and animals. | Biological chemistry 20031201 |
Babesia gibsoni-specific isoenzymes related to energy metabolism of the parasite in infected erythrocytes. | The Journal of parasitology 20031201 |
Thiamin deficiency and brain disorders. | Nutrition research reviews 20031201 |
Collection and characterisation of bacterial membrane proteins. | FEBS letters 20031127 |
Steady-state kinetics and molecular evolution of Escherichia coli MenD [(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase], an anomalous thiamin diphosphate-dependent decarboxylase-carboligase. | Biochemistry 20031125 |
Oxidative alpha-ketoglutarate dehydrogenase inhibition via subtle elevations in monoamine oxidase B levels results in loss of spare respiratory capacity: implications for Parkinson's disease. | The Journal of biological chemistry 20031121 |
Role of the glutamate dehydrogenase reaction in furnishing aspartate nitrogen for urea synthesis: studies in perfused rat liver with 15N. | The Biochemical journal 20031115 |
Minimal methylated substrate and extended substrate range of Escherichia coli AlkB protein, a 1-methyladenine-DNA dioxygenase. | The Journal of biological chemistry 20031107 |
The C-4 stereochemistry of leucocyanidin substrates for anthocyanidin synthase affects product selectivity. | Bioorganic & medicinal chemistry letters 20031103 |
An increase in the level of 2-oxoglutarate promotes heterocyst development in the cyanobacterium Anabaena sp. strain PCC 7120. | Microbiology (Reading, England) 20031101 |
Effects of hypoxia and intracellular iron chelation on hypoxia-inducible factor-1alpha and -1beta in the rat carotid body and glomus cells. | Histochemistry and cell biology 20031101 |
Oxygen tension regulates the expression of a group of procollagen hydroxylases. | European journal of biochemistry 20031101 |
[Regulation of carbon source partitioning in plants: all about regulation in response to internal ratio of C and N]. | Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20031101 |
The significance of organic carbon compounds for in situ metabolism and chemotaxis of phototrophic consortia. | Environmental microbiology 20031101 |
[CaCO3 stimulates alpha-ketoglutarate accumulation during pyruvate fermentation by Torulopsis glabrata]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20031101 |
The influence of alpha-ketoglutarate (AKG) on mineralisation, mechanical and structural properties of ulna in turkey under conditions of osteotomy and denervation. | Ortopedia, traumatologia, rehabilitacja 20031030 |
Identification of PLOD2 as telopeptide lysyl hydroxylase, an important enzyme in fibrosis. | The Journal of biological chemistry 20031017 |
Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, and necrotic cell death. | Journal of neuroscience research 20031015 |
Biochemical and spectroscopic studies on (S)-2-hydroxypropylphosphonic acid epoxidase: a novel mononuclear non-heme iron enzyme. | Biochemistry 20031014 |
Oxygen and iron regulation of iron regulatory protein 2. | The Journal of biological chemistry 20031010 |
Quantification of central metabolic fluxes in the facultative methylotroph methylobacterium extorquens AM1 using 13C-label tracing and mass spectrometry. | Biotechnology and bioengineering 20031005 |
Hypoxia up-regulates prolyl hydroxylase activity: a feedback mechanism that limits HIF-1 responses during reoxygenation. | The Journal of biological chemistry 20031003 |
Formation of novel flavonoids in apple (Malusxdomestica) treated with the 2-oxoglutarate-dependent dioxygenase inhibitor prohexadione-Ca. | Phytochemistry 20031001 |
Ammonia assimilation by Saccharomyces cerevisiae. | Eukaryotic cell 20031001 |
1H NMR pattern recognition and 31P NMR studies with d-Serine in rat urine and kidney, time- and dose-related metabolic effects. | Chemical research in toxicology 20031001 |
Age-related increase in 4-hydroxynonenal adduction to rat heart alpha-ketoglutarate dehydrogenase does not cause loss of its catalytic activity. | Antioxidants & redox signaling 20031001 |
Regulation of NAD- and NADP-dependent isocitrate dehydrogenases by reduction levels of pyridine nucleotides in mitochondria and cytosol of pea leaves. | Biochimica et biophysica acta 20030930 |
Tor1/2 regulation of retrograde gene expression in Saccharomyces cerevisiae derives indirectly as a consequence of alterations in ammonia metabolism. | The Journal of biological chemistry 20030919 |
Determination of tricarboxylic acid cycle acids and other related substances in cultured mammalian cells by gradient ion-exchange chromatography with suppressed conductivity detection. | Journal of chromatography. A 20030919 |
The potential of dairy lactic acid bacteria to metabolise amino acids via non-transaminating reactions and endogenous transamination. | International journal of food microbiology 20030915 |
Occurrence of two different glutamate dehydrogenase activities in the halophilic bacterium Salinibacter ruber. | FEMS microbiology letters 20030912 |
Instability of glutamate production by Corynebacterium glutamicum 2262 in continuous culture using the temperature-triggered process. | Journal of biotechnology 20030904 |
Short-term training attenuates muscle TCA cycle expansion during exercise in women. | Journal of applied physiology (Bethesda, Md. : 1985) 20030901 |
Pyruvate inhibits zinc-mediated pancreatic islet cell death and diabetes. | Diabetologia 20030901 |
Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion. | Hepatology (Baltimore, Md.) 20030901 |
Investigation by 13C-NMR and tricarboxylic acid (TCA) deletion mutant analysis of pathways for succinate formation in Saccharomyces cerevisiae during anaerobic fermentation. | Microbiology (Reading, England) 20030901 |
Regulation of root ion transporters by photosynthesis: functional importance and relation with hexokinase. | The Plant cell 20030901 |
Effect of hyper- and microgravity on collagen post-translational controls of MC3T3-E1 osteoblasts. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030901 |
Alteration of citrate metabolism in cluster roots of white lupin. | Plant & cell physiology 20030901 |
Therapeutic effect of Semecarpus anacardium Linn. nut milk extract on carbohydrate metabolizing and mitochondrial TCA cycle and respiratory chain enzymes in mammary carcinoma rats. | The Journal of pharmacy and pharmacology 20030901 |
2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase. | Bioorganic & medicinal chemistry letters 20030818 |
Characterization of the human prolyl 4-hydroxylases that modify the hypoxia-inducible factor. | The Journal of biological chemistry 20030815 |
Identification, expression, and tissue distribution of the three rat lysyl hydroxylase isoforms. | Biochemical and biophysical research communications 20030808 |
Cloning of a novel prolyl 4-hydroxylase subunit expressed in the fibrous cap of human atherosclerotic plaque. | Circulation 20030805 |
The amino-terminal GAF domain of Azotobacter vinelandii NifA binds 2-oxoglutarate to resist inhibition by NifL under nitrogen-limiting conditions. | The Journal of biological chemistry 20030801 |
Basolateral localization of flounder Na+-dicarboxylate cotransporter (fNaDC-3) in the kidney of Pleuronectes americanus. | Pflugers Archiv : European journal of physiology 20030801 |
Thiamine deficiency results in downregulation of the GLAST glutamate transporter in cultured astrocytes. | Glia 20030801 |
A continuous coupled enzyme assay for bacterial malonyl-CoA:acyl carrier protein transacylase (FabD). | Analytical biochemistry 20030801 |
Novel proline hydroxylase activities in the pneumocandin-producing fungus Glarea lozoyensis responsible for the formation of trans 3- and trans 4-hydroxyproline. | Applied microbiology and biotechnology 20030801 |
The Arabidopsis mutant dct is deficient in the plastidic glutamate/malate translocator DiT2. | The Plant journal : for cell and molecular biology 20030801 |
Export of metabolites from pancreatic islet mitochondria as a means to study anaplerosis in insulin secretion. | Metabolism: clinical and experimental 20030801 |
Carbon-source-dependent nitrogen regulation in Escherichia coli is mediated through glutamine-dependent GlnB signalling. | Microbiology (Reading, England) 20030801 |
Anaplerotic reactions in tumour proliferation and apoptosis. | Biochemical pharmacology 20030801 |
Summary of the Standards, Options and Recommendations for nutritional support in patients undergoing bone marrow transplantation (2002). | British journal of cancer 20030801 |
Association analysis of bone mineral density and single nucleotide polymorphisms in two candidate genes on chromosome 1p36. | Calcified tissue international 20030801 |
Kinetic studies on the inhibition of GABA-T by gamma-vinyl GABA and taurine. | Journal of enzyme inhibition and medicinal chemistry 20030801 |
Effect of alpha-ketoglutarate and oxaloacetate on brain mitochondrial DNA damage and seizures induced by kainic acid in mice. | Toxicology letters 20030720 |
Allosteric interactions and bifunctionality make the response of glutamine synthetase cascade system of Escherichia coli robust and ultrasensitive. | The Journal of biological chemistry 20030718 |
Identification and cloning of genes encoding viomycin biosynthesis from Streptomyces vinaceus and evidence for involvement of a rare oxygenase. | Gene 20030717 |
Carbapenem biosynthesis: confirmation of stereochemical assignments and the role of CarC in the ring stereoinversion process from L-proline. | Journal of the American Chemical Society 20030716 |
NMR-based metabonomic studies on the biochemical effects of epicatechin in the rat. | Journal of agricultural and food chemistry 20030702 |
Deficits in a tricarboxylic acid cycle enzyme in brains from patients with Parkinson's disease. | Neurochemistry international 20030701 |
Impaired oxidative phosphorylation in skeletal muscle of intrauterine growth-retarded rats. | American journal of physiology. Endocrinology and metabolism 20030701 |
Mitochondrial complex I, aconitase, and succinate dehydrogenase during hypoxia-reoxygenation: modulation of enzyme activities by MnSOD. | American journal of physiology. Lung cellular and molecular physiology 20030701 |
Disease-related metabolites in culture medium of fibroblasts from patients with D-2-hydroxyglutaric aciduria, L-2-hydroxyglutaric aciduria, and combined D/L-2-hydroxyglutaric aciduria. | Clinical chemistry 20030701 |
Ascorbic acid and alpha-tocopherol as potent modulators on arsenic induced toxicity in mitochondria. | The Journal of nutritional biochemistry 20030701 |
A comparison between NMR and GCMS 13C-isotopomer analysis in cardiac metabolism. | Molecular and cellular biochemistry 20030701 |
Characterization and regulation of NADP+-isocitrate dehydrogenase from Saccharopolyspora erythraea. | Biotechnology letters 20030701 |
Functional properties and cellular distribution of the system A glutamine transporter SNAT1 support specialized roles in central neurons. | The Journal of biological chemistry 20030627 |
The active conformation of glutamate synthase and its binding to ferredoxin. | Journal of molecular biology 20030627 |
The first direct characterization of a high-valent iron intermediate in the reaction of an alpha-ketoglutarate-dependent dioxygenase: a high-spin FeIV complex in taurine/alpha-ketoglutarate dioxygenase (TauD) from Escherichia coli. | Biochemistry 20030624 |
Truncated product of the bifunctional DLST gene involved in biogenesis of the respiratory chain. | The EMBO journal 20030616 |
Toxic effects of copper-based antineoplastic drugs (Casiopeinas) on mitochondrial functions. | Biochemical pharmacology 20030615 |
Construction and expression of a humanized M2 autoantigen trimer and its application in the diagnosis of primary biliary cirrhosis. | World journal of gastroenterology 20030615 |
Crystal structure of carbapenem synthase (CarC). | The Journal of biological chemistry 20030606 |
Chronic hypoxia in development selectively alters the activities of key enzymes of glucose oxidative metabolism in brain regions. | Neurochemical research 20030601 |
Purification and folding of recombinant bovine oxoglutarate/malate carrier by immobilized metal-ion affinity chromatography. | Protein expression and purification 20030601 |
Regulation of amino acid uptake by carbon and nitrogen in Pinus sylvestris. | Planta 20030601 |
Phosphate binder usage in kidney failure patients. | Expert opinion on pharmacotherapy 20030601 |
Proteomic studies of diauxic lag in the differentiating prokaryote Streptomyces coelicolor reveal a regulatory network of stress-induced proteins and central metabolic enzymes. | Molecular microbiology 20030601 |
Molecular mimicry of mitochondrial and nuclear autoantigens in primary biliary cirrhosis. | Gastroenterology 20030601 |
Regulatory effects of 5'-deoxypyridoxal on glutamate dehydrogenase activity and insulin secretion in pancreatic islets. | Biochimie 20030601 |
Aerobic growth deficient Haemophilus influenzae mutants are non-virulent: implications on metabolism. | International journal of medical microbiology : IJMM 20030601 |
Toxicovigilance: new biochemical tool used in sulfonylurea herbicides toxicology studies. | Acta pharmaceutica (Zagreb, Croatia) 20030601 |
Nutrition in the critically ill patient: part II. Parenteral nutrition. | Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20030601 |
Tyrosinase protects human melanocytes from ROS-generating compounds. | Biochemical and biophysical research communications 20030530 |
Substrate-induced conformational changes in Escherichia coli taurine/alpha-ketoglutarate dioxygenase and insight into the oligomeric structure. | Biochemistry 20030520 |
Immunization with a xenobiotic 6-bromohexanoate bovine serum albumin conjugate induces antimitochondrial antibodies. | Journal of immunology (Baltimore, Md. : 1950) 20030515 |
The biosynthesis of GDP-L-colitose: C-3 deoxygenation is catalyzed by a unique coenzyme B6-dependent enzyme. | Journal of the American Chemical Society 20030514 |
The mitochondrial oxoglutarate carrier: structural and dynamic properties of transmembrane segment IV studied by site-directed spin labeling. | Biochemistry 20030513 |
Na+-K+-ATPase alpha 2-gene and skeletal muscle characteristics in response to long-term overfeeding. | Journal of applied physiology (Bethesda, Md. : 1985) 20030501 |
Evaluation of newly developed ELISA using 'MESACUP-2 test mitochondrial M2' kit for the diagnosis of primary biliary cirrhosis. | Clinical biochemistry 20030501 |
Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacity. | Pflugers Archiv : European journal of physiology 20030501 |
Crystallization of the proline-rich-peptide binding domain of human type I collagen prolyl 4-hydroxylase. | Acta crystallographica. Section D, Biological crystallography 20030501 |
Crystallization and preliminary X-ray crystallographic analysis of d-phenylglycine aminotransferase from Pseudomonas stutzeri ST201. | Acta crystallographica. Section D, Biological crystallography 20030501 |
Carbon supply and 2-oxoglutarate effects on expression of nitrate reductase and nitrogen-regulated genes in Synechococcus sp. strain PCC 7942. | FEMS microbiology letters 20030425 |
Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status. | Biochemistry 20030415 |
Effect of ascorbate on the activity of hypoxia-inducible factor in cancer cells. | Cancer research 20030415 |
Procyclic Trypanosoma brucei do not use Krebs cycle activity for energy generation. | The Journal of biological chemistry 20030411 |
Histidine 454 plays an important role in polymerization of human glutamate dehydrogenase. | FEBS letters 20030410 |
Crystal structures of branched-chain amino acid aminotransferase complexed with glutamate and glutarate: true reaction intermediate and double substrate recognition of the enzyme. | Biochemistry 20030408 |
Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation. | Biochemistry 20030401 |
An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. | Biophysical journal 20030401 |
Effect of DHLA on response of isolated rat urinary bladder to repetitive field stimulation. | Molecular and cellular biochemistry 20030401 |
Comparative analysis of the Bradyrhizobium japonicum sucA region. | Canadian journal of microbiology 20030401 |
The selectivity and inhibition of AlkB. | The Journal of biological chemistry 20030321 |
Inhibition study of rhodanese by means of electrophoretically mediated microanalysis. | Journal of chromatography. A 20030321 |
Retrieval-independent localization of lysyl hydroxylase in the endoplasmic reticulum via a peptide fold in its iron-binding domain. | The Biochemical journal 20030315 |
Heat effect on the structure and activity of the recombinant glutamate dehydrogenase from a hyperthermophilic archaeon Pyrococcus horikoshii. | Archives of biochemistry and biophysics 20030301 |
Human renal organic anion transporter 1-dependent uptake and toxicity of mercuric-thiol conjugates in Madin-Darby canine kidney cells. | Molecular pharmacology 20030301 |
2-Oxo acid dehydrogenase complexes in redox regulation. | European journal of biochemistry 20030301 |
The kinetic properties of various R258 mutants of deacetoxycephalosporin C synthase. | European journal of biochemistry 20030301 |
Identification of photorespiratory glutamate:glyoxylate aminotransferase (GGAT) gene in Arabidopsis. | The Plant journal : for cell and molecular biology 20030301 |
Reconstruction of C(3) and C(4) metabolism in Methylobacterium extorquens AM1 using transposon mutagenesis. | Microbiology (Reading, England) 20030301 |
In vivo induction of insulin secretion by ornithine alpha-ketoglutarate: involvement of nitric oxide and glutamine. | Metabolism: clinical and experimental 20030301 |
Performance of a recombinant strain of Streptomyces lividans for bioconversion of penicillin G to deacetoxycephalosporin G. | Journal of industrial microbiology & biotechnology 20030301 |
Characterization of aspartate aminotransferase from the cyanobacterium Phormidium lapideum. | Bioscience, biotechnology, and biochemistry 20030301 |
Effects of the changes in enzyme activities on metabolic flux redistribution around the 2-oxoglutarate branch in glutamate production by Corynebacterium glutamicum. | Bioprocess and biosystems engineering 20030301 |
Structure of human FIH-1 reveals a unique active site pocket and interaction sites for HIF-1 and von Hippel-Lindau. | The Journal of biological chemistry 20030227 |
O2- and alpha-ketoglutarate-dependent tyrosyl radical formation in TauD, an alpha-keto acid-dependent non-heme iron dioxygenase. | Biochemistry 20030225 |
(4-Hydroxyphenyl)pyruvate dioxygenase from Streptomyces avermitilis: the basis for ordered substrate addition. | Biochemistry 20030225 |
Catalysis of diaphorase reactions by Mycobacterium tuberculosis lipoamide dehydrogenase occurs at the EH4 level. | Biochemistry 20030225 |
Analysis of low-molecular-mass organic acids using capillary zone electrophoresis-electrospray ionization mass spectrometry. | Journal of chromatography. A 20030221 |
Changes in the ornithine cycle following ionising radiation cause a cytotoxic conditioning of the culture medium of H35 hepatoma cells. | British journal of cancer 20030210 |
Alterations in mitochondrial function in a mouse model of hypertrophic cardiomyopathy. | American journal of physiology. Heart and circulatory physiology 20030201 |
The von Hippel-Lindau tumor suppressor, hypoxia-inducible factor-1 (HIF-1) degradation, and cancer pathogenesis. | Seminars in cancer biology 20030201 |
The snakehead Channa asiatica accumulates alanine during aerial exposure, but is incapable of sustaining locomotory activities on land through partial amino acid catabolism. | The Journal of experimental biology 20030201 |
Glutamine deprivation facilitates tumour necrosis factor induced bacterial translocation in Caco-2 cells by depletion of enterocyte fuel substrate. | Gut 20030201 |
Enzymatic assay for determination of bicarbonate ion in plasma using urea amidolyase. | Clinica chimica acta; international journal of clinical chemistry 20030201 |
Glutamate synthesis in barley roots: the role of the plastidic glucose-6-phosphate dehydrogenase. | Planta 20030201 |
Effects of ornithine alpha-ketoglutarate on insulin secretion in rat pancreatic islets: implication of nitric oxide synthase and glutamine synthetase pathways. | The British journal of nutrition 20030201 |
Multimethod characterization of the interaction of aluminum ion with alpha-ketoglutaric acid in acidic aqueous solutions. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030201 |
A 2-oxoglutarate-dependent dioxygenase is integrated in DIMBOA-biosynthesis. | Phytochemistry 20030201 |
Skeletal muscle metabolism in Duchenne muscular dystrophy (DMD): an in-vitro proton NMR spectroscopy study. | Magnetic resonance imaging 20030201 |
Inhibition of the alpha-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation. | Biochimica et biophysica acta 20030120 |
A thermally sensitive loop in clostridial glutamate dehydrogenase detected by limited proteolysis. | The Journal of biological chemistry 20030110 |
Aluminum detoxification in Pseudomonas fluorescens is mediated by oxalate and phosphatidylethanolamine. | Biochimica et biophysica acta 20030102 |
The export of metabolites from mitochondria and anaplerosis in insulin secretion. | Biochimica et biophysica acta 20030102 |
Urate transport via human PAH transporter hOAT1 and its gene structure. | Kidney international 20030101 |
Reactive oxygen species are involved in the stimulation of the mitochondrial permeability transition by dihydrolipoate. | Biochemical pharmacology 20030101 |
Use of ornithine alpha-ketoglutarate in clinical nutrition of elderly patients. | Nutrition (Burbank, Los Angeles County, Calif.) 20030101 |
Induction of glutamate dehydrogenase in the ovine fetal liver by dexamethasone infusion during late gestation. | Experimental biology and medicine (Maywood, N.J.) 20030101 |
Metabolic flux redistribution in Corynebacterium glutamicum in response to osmotic stress. | Applied microbiology and biotechnology 20030101 |
Intrinsic tryptophan fluorescence as a probe of metal and alpha-ketoglutarate binding to TfdA, a mononuclear non-heme iron dioxygenase. | Journal of inorganic biochemistry 20030101 |
Transport of organic anions across the basolateral membrane of proximal tubule cells. | Reviews of physiology, biochemistry and pharmacology 20030101 |
Purification and characterization of NADP-linked isocitrate dehydrogenase from the copper-tolerant wood-rotting basidiomycete Fomitopsis palustris. | Bioscience, biotechnology, and biochemistry 20030101 |
Involvement of oxygen free radicals in the respiratory uncoupling induced by free calcium and ADP-magnesium in isolated cardiac mitochondria: comparing reoxygenation in cultured cardiomyocytes. | Molecular and cellular biochemistry 20030101 |
Isolation of the bifunctional enzyme lysine 2-oxoglutarate reductase-saccharopine dehydrogenase from Phaseolus vulgaris. | Amino acids 20030101 |
Redox regulation of homocysteine-dependent glutathione synthesis. | Redox report : communications in free radical research 20030101 |
New enzymatic assay for serum urea nitrogen using urea amidolyase. | Journal of clinical laboratory analysis 20030101 |
Alicycliphilus denitrificans gen. nov., sp. nov., a cyclohexanol-degrading, nitrate-reducing beta-proteobacterium. | International journal of systematic and evolutionary microbiology 20030101 |
Molecular responses to hypoxia in tumor cells. | Molecular cancer 20030101 |
Cataplerotic TCA cycle flux determined as glutamate-sustained oxygen consumption in primary cultures of astrocytes. | Neurochemistry international 20030101 |
Enhancement of circulatory antioxidants by alpha-ketoglutarate during sodium valproate treatment in Wistar rats. | Polish journal of pharmacology 20030101 |
[Arsenite-induced lipid peroxidation in Saccharomyces cerevisiae]. | Mikrobiologiia 20030101 |
[Tricarboxylic acid cycle in energy metabolism and antioxidant cell defense in acute hypoxia]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20030101 |
An expanded genome-scale model of Escherichia coli K-12 (iJR904 GSM/GPR). | Genome biology 20030101 |
Altered expression of connective tissue genes in postnatal chondroinduced human dermal fibroblasts. | Connective tissue research 20030101 |
[Carbohydrate metabolism of Bothriocephalus scorpii (Cestoda: Bothriocephalidae)]. | Parazitologiia 20030101 |
A common polymorphism in the oxygen-dependent degradation (ODD) domain of hypoxia inducible factor-1alpha (HIF-1alpha) does not impair Pro-564 hydroxylation. | Molecular cancer 20030101 |
[Central metabolism in Acinetobacter sp. grown on ethanol]. | Mikrobiologiia 20030101 |
[Biochemical characterization of the yeast Yarrowia lipolytica overproducing carboxylic acids from ethanol. Nitrogen metabolism enzymes]. | Mikrobiologiia 20030101 |
Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20030101 |
Phylogenomic identification of five new human homologs of the DNA repair enzyme AlkB. | BMC genomics 20030101 |
[Activity of the enzymes of carbon metabolism in Sulfobacillus sibiricus under various conditions of cultivation]. | Mikrobiologiia 20030101 |
[Role of ATP-sensitive potassium channel activators in liver mitochondrial function in rats with different resistance to hypoxia]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101 |
Acrolein inhibits NADH-linked mitochondrial enzyme activity: implications for Alzheimer's disease. | Neurotoxicity research 20030101 |
[Effect of ATP-sensitive potassium channel modulators and intermittent hypoxia on mitochondrial respiration during stress]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101 |
Tryptophan metabolism via transamination. In vitro aminotransferase assay using dinitrophenylhydrazine method. | Advances in experimental medicine and biology 20030101 |
Effect of ketoacids on H(2)O(2) induced cataract. | Indian journal of clinical biochemistry : IJCB 20030101 |
DOOR syndrome: deficiency of E1 component of the 2-oxoglutarate dehydrogenase complex. | American journal of medical genetics 20021215 |
The effects of ischaemic preconditioning, diazoxide and 5-hydroxydecanoate on rat heart mitochondrial volume and respiration. | The Journal of physiology 20021215 |
Experimental identification of downhill protein folding. | Science (New York, N.Y.) 20021213 |
The lipoamide dehydrogenase from Mycobacterium tuberculosis permits the direct observation of flavin intermediates in catalysis. | Biochemistry 20021210 |
Differential display of mRNAs associated with blood feeding in the midgut of the bloodsucking bug, Triatoma infestans. | Parasitology research 20021201 |
Crystallization and preliminary X-ray structure analysis of isocitrate dehydrogenase from two hyperthermophiles, Aeropyrum pernix and Thermotoga maritima. | Acta crystallographica. Section D, Biological crystallography 20021201 |
Structure of the monomeric isocitrate dehydrogenase: evidence of a protein monomerization by a domain duplication. | Structure (London, England : 1993) 20021201 |
Tobacco plants were transformed by Agrobacterium rhizogenes infection during their evolution. | The Plant journal : for cell and molecular biology 20021201 |
Glutaminolysis and insulin secretion: from bedside to bench and back. | Diabetes 20021201 |
The impact of oxidative stress on Arabidopsis mitochondria. | The Plant journal : for cell and molecular biology 20021201 |
Mercury toxicity and antioxidants: Part 1: role of glutathione and alpha-lipoic acid in the treatment of mercury toxicity. | Alternative medicine review : a journal of clinical therapeutic 20021201 |
Isolation and sequence analysis of the rat dihydrolipoamide succinyltransferase gene. | DNA sequence : the journal of DNA sequencing and mapping 20021201 |
Neonatal liver disease associated with placental transfer of anti-mitochondrial antibodies. | Autoimmunity 20021201 |
Ornithine alpha-ketoglutarate modulates the levels of antioxidants and lipid peroxidation products in ammonium acetate treated rats. | Indian journal of biochemistry & biophysics 20021201 |
A metabolic role of the glyoxylate and tricarboxylic acid cycles for development of the copper-tolerant brown-rot fungus Fomitopsis palustris. | FEMS microbiology letters 20021119 |
Mitochondrial aspartate aminotransferase catalyses cysteine S-conjugate beta-lyase reactions. | The Biochemical journal 20021115 |
Cytotoxicity of dopamine-derived tetrahydroisoquinolines on melanoma cells. | Biochemical pharmacology 20021115 |
Renal organic anion transport: a comparative and cellular perspective. | Biochimica et biophysica acta 20021113 |
Amish lethal microcephaly: a new metabolic disorder with severe congenital microcephaly and 2-ketoglutaric aciduria. | American journal of medical genetics 20021101 |
Renal disposition of a furan dicarboxylic acid and other uremic toxins in the rat. | The Journal of pharmacology and experimental therapeutics 20021101 |
Interaction of the metal chelator 2,3-dimercapto-1-propanesulfonate with the rabbit multispecific organic anion transporter 1 (rbOAT1). | Molecular pharmacology 20021101 |
The renal Na(+)-dependent dicarboxylate transporter, NaDC-3, translocates dimethyl- and disulfhydryl-compounds and contributes to renal heavy metal detoxification. | Journal of the American Society of Nephrology : JASN 20021101 |
Effect of deep pentobarbital anesthesia on neurotransmitter metabolism in vivo: on the correlation of total glucose consumption with glutamatergic action. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20021101 |
The third activity for lysyl hydroxylase 3: galactosylation of hydroxylysyl residues in collagens in vitro. | Matrix biology : journal of the International Society for Matrix Biology 20021101 |
II. Glutamine and glutamate. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20021101 |
Demonstration of pyruvate recycling in primary cultures of neocortical astrocytes but not in neurons. | Neurochemical research 20021101 |
Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS-DA. | FEBS letters 20021023 |
Cofactor binding to Escherichia coli D-3-phosphoglycerate dehydrogenase induces multiple conformations which alter effector binding. | The Journal of biological chemistry 20021018 |
Selective inactivation of redox-sensitive mitochondrial enzymes during cardiac reperfusion. | Archives of biochemistry and biophysics 20021015 |
Isolation and biochemical characterization of hypophosphite/2-oxoglutarate dioxygenase. A novel phosphorus-oxidizing enzyme from Psuedomonas stutzeri WM88. | The Journal of biological chemistry 20021011 |
Urate/alpha-ketoglutarate exchange in avian basolateral membrane vesicles. | American journal of physiology. Cell physiology 20021001 |
Facilitated diffusion of urate in avian brush-border membrane vesicles. | American journal of physiology. Cell physiology 20021001 |
Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species. | European journal of biochemistry 20021001 |
Inhibition of the alpha-ketoglutarate dehydrogenase and pyruvate dehydrogenase complexes by a putative aberrant metabolite of serotonin, tryptamine-4,5-dione. | Chemical research in toxicology 20021001 |
Protective influences of alpha-ketoglutarate on lipid peroxidation and antioxidant status in ammonium acetate treated rats. | Indian journal of experimental biology 20021001 |
Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage. | Nature 20020912 |
The elevation of glutamate content and the amplification of insulin secretion in glucose-stimulated pancreatic islets are not causally related. | The Journal of biological chemistry 20020906 |
Mitochondrial substrate level phosphorylation is essential for growth of procyclic Trypanosoma brucei. | The Journal of biological chemistry 20020906 |
Ca(2+) modulates respiratory and steroidogenic activities of human term placental mitochondria. | Archives of biochemistry and biophysics 20020901 |
Mutant deoxynucleotide carrier is associated with congenital microcephaly. | Nature genetics 20020901 |
The succinate mechanism of insulin release. | Diabetes 20020901 |
A role for hypoxia and hypoxia-inducible transcription factors in tumor physiology. | Journal of molecular medicine (Berlin, Germany) 20020901 |
A continuous 96-well plate spectrophotometric assay for branched-chain amino acid aminotransferases. | Analytical biochemistry 20020901 |
Alpha-ketoglutarate-supplemented enteral nutrition: effects on postoperative nitrogen balance and muscle catabolism. | Nutrition (Burbank, Los Angeles County, Calif.) 20020901 |
Effects of alpha-ketoglutarate on antioxidants and lipid peroxidation products in rats treated with ammonium acetate. | Nutrition (Burbank, Los Angeles County, Calif.) 20020901 |
Goodbye sodium alpha-ketoglutarate? | Nutrition (Burbank, Los Angeles County, Calif.) 20020901 |
Molecular analysis of the role of two aromatic aminotransferases and a broad-specificity aspartate aminotransferase in the aromatic amino acid metabolism of Pyrococcus furiosus. | Archaea (Vancouver, B.C.) 20020901 |
A tormentor in the quest for plant p53-like proteins. | FEBS letters 20020828 |
The anaplerotic substrate alanine stimulates acetate incorporation into glutamate and glutamine in rabbit kidney tubules. A (13)C NMR study. | The Journal of biological chemistry 20020816 |
Toxic, halogenated cysteine S-conjugates and targeting of mitochondrial enzymes of energy metabolism. | Biochemical pharmacology 20020815 |
The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits. | The Journal of biological chemistry 20020809 |
Calcium modulates the ATP and ADP hydrolysis in human placental mitochondria. | The international journal of biochemistry & cell biology 20020801 |
Differences between mouse and rat pancreatic islets: succinate responsiveness, malic enzyme, and anaplerosis. | American journal of physiology. Endocrinology and metabolism 20020801 |
Functional expression and mutational analysis of flavonol synthase from Citrus unshiu. | European journal of biochemistry 20020801 |
Role of organic acids in aluminum accumulation and plant growth in Melastoma malabathricum. | Tree physiology 20020801 |
Decreased TCA cycle rate in the rat brain after acute 3-NP treatment measured by in vivo 1H-[13C] NMR spectroscopy. | Journal of neurochemistry 20020801 |
Glutamate dehydrogenase activity: a major criterion for the selection of flavour-producing lactic acid bacteria strains. | Antonie van Leeuwenhoek 20020801 |
Antioxidant alpha-keto-carboxylate pyruvate protects low-density lipoprotein and atherogenic macrophages. | Free radical research 20020801 |
Absorption and metabolism of alpha-ketoglutarate in growing pigs. | Journal of animal physiology and animal nutrition 20020801 |
Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family. | The Journal of biological chemistry 20020719 |
HIF-1alpha-prolyl hydroxylase: molecular target of nitric oxide in the hypoxic signal transduction pathway. | Biochemical and biophysical research communications 20020719 |
Structural studies on the synchronization of catalytic centers in glutamate synthase. | The Journal of biological chemistry 20020705 |
Identification of a novel transporter for dicarboxylates and tricarboxylates in plant mitochondria. Bacterial expression, reconstitution, functional characterization, and tissue distribution. | The Journal of biological chemistry 20020705 |
Characterization of bacterial homocitrate synthase involved in lysine biosynthesis. | FEBS letters 20020703 |
Isolation, characterization and differential gene expression of multispecific organic anion transporter 2 in mice. | Molecular pharmacology 20020701 |
Herbaspirillum seropedicae signal transduction protein PII is structurally similar to the enteric GlnK. | European journal of biochemistry 20020701 |
Implications for altered glutamate and GABA metabolism in the dorsolateral prefrontal cortex of aged schizophrenic patients. | The American journal of psychiatry 20020701 |
Polymorphism of the vitamin D(3) receptor in patients with psoriasis. | Archives of dermatological research 20020701 |
Cerebrospinal fluid levels of thiamine in patients with Alzheimer's disease. | Journal of neural transmission (Vienna, Austria : 1996) 20020701 |
Specific growth inhibition by acetate of an Escherichia coli strain expressing Era-dE, a dominant negative Era mutant. | Journal of molecular microbiology and biotechnology 20020701 |
Tricarboxylic acid cycle substrates prevent PARP-mediated death of neurons and astrocytes. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20020701 |
Identifying and characterizing plastidic 2-oxoglutarate/malate and dicarboxylate transporters in Arabidopsis thaliana. | Plant & cell physiology 20020701 |
Characterization of oxidative phosphorylation in the colorless chlorophyte Polytomella sp. Its mitochondrial respiratory chain lacks a plant-like alternative oxidase. | Biochimica et biophysica acta 20020701 |
Exploring routes to stabilize a cationic pyridoxamine in an artificial transaminase: site-directed mutagenesis versus synthetic cofactors. | Protein engineering 20020701 |
[TCA cycle, oxidative phosphorylation and uncoupling protein]. | Nihon rinsho. Japanese journal of clinical medicine 20020701 |
Properties of the recombinant ferredoxin-dependent glutamate synthase of Synechocystis PCC6803. Comparison with the Azospirillum brasilense NADPH-dependent enzyme and its isolated alpha subunit. | Biochemistry 20020625 |
Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity. | The Journal of biological chemistry 20020621 |
The use of dioxygen by HIF prolyl hydroxylase (PHD1). | Bioorganic & medicinal chemistry letters 20020617 |
FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor. | Genes & development 20020615 |
Aspartate aminotransferase isotope exchange reactions: implications for glutamate/glutamine shuttle hypothesis. | American journal of physiology. Cell physiology 20020601 |
Mechanisms used to dispose of progressively increasing alkali load in rats. | American journal of physiology. Renal physiology 20020601 |
Characterization of rainbow trout branched-chain alpha-keto acid dehydrogenase complex: inter-domain segments of the E2 component affect the overall activity. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020601 |
Glutamine concentration and tissue exchange with intravenously administered alpha-ketoglutaric acid and ammonium: a dose-response study in the pig. | Nutrition (Burbank, Los Angeles County, Calif.) 20020601 |
Decreased Rubisco activity leads to dramatic changes of nitrate metabolism, amino acid metabolism and the levels of phenylpropanoids and nicotine in tobacco antisense RBCS transformants. | The Plant journal : for cell and molecular biology 20020601 |
Amino acid composition of bulk protein and salt relationships of selected enzymes of Salinibacter ruber, an extremely halophilic bacterium. | Extremophiles : life under extreme conditions 20020601 |
A possible mouse model for spontaneous cholangitis: serological and histological characteristics of MRL/lpr mice. | Pathology 20020601 |
Intensity of free radical processes and regulation of cytoplasmic NADP-isocitrate dehydrogenase in rat cardiomyocytes under normal and ischemic conditions. | Biochemistry. Biokhimiia 20020601 |
Promising role of alpha-ketoglutarate in protecting against the lethal effects of cyanide. | Human & experimental toxicology 20020601 |
Mitochondrial aconitase modification, functional inhibition, and evidence for a supramolecular complex of the TCA cycle by the renal toxicant S-(1,1,2,2-tetrafluoroethyl)-L-cysteine. | Biochemistry 20020528 |
Cassette mutagenesis and photoaffinity labeling of adenine binding domain of ADP regulatory site within human glutamate dehydrogenase. | Biochemistry 20020528 |
Identification of amino acids important for the catalytic activity of the collagen glucosyltransferase associated with the multifunctional lysyl hydroxylase 3 (LH3). | The Journal of biological chemistry 20020524 |
Substrate recognition by 2-oxoacid:ferredoxin oxidoreductase from Sulfolobus sp. strain 7. | Biochimica et biophysica acta 20020520 |
Nitrogen regulation in Saccharomyces cerevisiae. | Gene 20020515 |
Direct interaction of the NifL regulatory protein with the GlnK signal transducer enables the Azotobacter vinelandii NifL-NifA regulatory system to respond to conditions replete for nitrogen. | The Journal of biological chemistry 20020503 |
Mitochondrial dysfunction in acute hyperammonemia. | Neurochemistry international 20020501 |
Non-invasive measurements of myocardial carbon metabolism using in vivo 13C NMR spectroscopy. | NMR in biomedicine 20020501 |
Spectroscopic studies of 1-aminocyclopropane-1-carboxylic acid oxidase: molecular mechanism and CO(2) activation in the biosynthesis of ethylene. | Journal of the American Chemical Society 20020501 |
Crystallization and preliminary X-ray analysis of the full-size cubic core of pig 2-oxoglutarate dehydrogenase complex. | Acta crystallographica. Section D, Biological crystallography 20020501 |
The novel protein phosphatase PphA from Synechocystis PCC 6803 controls dephosphorylation of the signalling protein PII. | Molecular microbiology 20020501 |
Utilization of sterol carrier protein-2 by phytanoyl-CoA 2-hydroxylase in the peroxisomal alpha oxidation of phytanic acid. | Chemistry & biology 20020501 |
GDH1 expression is regulated by GLN3, GCN4, and HAP4 under respiratory growth. | Biochemical and biophysical research communications 20020426 |
Crystal structure of a clavaminate synthase-Fe(II)-2-oxoglutarate-substrate-NO complex: evidence for metal centered rearrangements. | FEBS letters 20020424 |
X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates. | Biochemistry 20020423 |
Carnitine biosynthesis in Neurospora crassa: identification of a cDNA coding for epsilon-N-trimethyllysine hydroxylase and its functional expression in Saccharomyces cerevisiae. | FEMS microbiology letters 20020423 |
Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations. | The Biochemical journal 20020401 |
Interaction of cytosolic and plastidic nitrogen metabolism in plants. | Journal of experimental botany 20020401 |
Molecular and enzymatic analysis of ammonium assimilation in woody plants. | Journal of experimental botany 20020401 |
Enzyme redundancy and the importance of 2-oxoglutarate in plant ammonium assimilation. | Journal of experimental botany 20020401 |
Steps towards an integrated view of nitrogen metabolism. | Journal of experimental botany 20020401 |
Skeletal muscle characteristics predict body fat gain in response to overfeeding in never-obese young men. | Metabolism: clinical and experimental 20020401 |
Molecular and regulatory properties of leucoplast pyruvate kinase from Brassica napus (rapeseed) suspension cells. | Archives of biochemistry and biophysics 20020401 |
Ischemic preconditioning improves mitochondrial tolerance to experimental calcium overload. | The Journal of surgical research 20020401 |
Escherichia coli aconitases and oxidative stress: post-transcriptional regulation of sodA expression. | Microbiology (Reading, England) 20020401 |
Photorespiration-dependent increases in phospho enolpyruvate carboxylase, isocitrate dehydrogenase and glutamate dehydrogenase in transformed tobacco plants deficient in ferredoxin-dependent glutamine-alpha-ketoglutarate aminotransferase. | Planta 20020401 |
Characterization of isocitrate dehydrogenase from the green sulfur bacterium Chlorobium limicola. A carbon dioxide-fixing enzyme in the reductive tricarboxylic acid cycle. | European journal of biochemistry 20020401 |
[Alpha-ketoglutarate dehydrogenase complex]. | Nihon rinsho. Japanese journal of clinical medicine 20020401 |
[Alpha-ketoglutarate dehydrogenase deficiency]. | Nihon rinsho. Japanese journal of clinical medicine 20020401 |
Temperature dependence of kinetic parameters for hyperthermophilic glutamate dehydrogenase from Aeropyrum pernix K1. | Bioscience, biotechnology, and biochemistry 20020401 |
[Study on biochemical mechanism of citral damage to the A. flavasi's mitochondria]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20020401 |
Zinc is a potent inhibitor of thiol oxidoreductase activity and stimulates reactive oxygen species production by lipoamide dehydrogenase. | The Journal of biological chemistry 20020322 |
Active site mutations of recombinant deacetoxycephalosporin C synthase. | Biochemical and biophysical research communications 20020322 |
A novel five-subunit-type 2-oxoglutalate:ferredoxin oxidoreductases from Hydrogenobacter thermophilus TK-6. | Biochemical and biophysical research communications 20020322 |
Oxidative stress increases internal calcium stores and reduces a key mitochondrial enzyme. | Biochimica et biophysica acta 20020316 |
Aluminum citrate uptake by immortalized brain endothelial cells: implications for its blood-brain barrier transport. | Brain research 20020315 |
In vitro and in vivo attenuation of experimental cyanide poisoning by alpha-ketoglutarate. | Toxicology letters 20020310 |
Hydrogen turnover and subcellular compartmentation of hepatic [2-(13)C]glutamate and [3-(13)C]aspartate as detected by (13)C NMR. | The Journal of biological chemistry 20020308 |
cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase. | Genomics 20020301 |
Effects of ornithine 2-oxoglutarate on neutrophils in stressed rats: evidence for the involvement of nitric oxide and polyamines. | Clinical science (London, England : 1979) 20020301 |
Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase. | Diabetes 20020301 |
Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020301 |
Glutamine: an anaplerotic precursor. | Nutrition (Burbank, Los Angeles County, Calif.) 20020301 |
The nitration product 5-nitro-gamma-tocopherol is increased in the Alzheimer brain. | Nitric oxide : biology and chemistry 20020301 |
Phototrophic consortia: model systems for symbiotic interrelations between prokaryotes. | Archives of microbiology 20020301 |
2-Oxoglutarate increases the binding affinity of the NtcA (nitrogen control) transcription factor for the Synechococcus glnA promoter. | FEBS letters 20020213 |
UCP2-dependent proton leak in isolated mammalian mitochondria. | The Journal of biological chemistry 20020208 |
The Rhizobium leguminosarum bv. viciae VF39 gamma-aminobutyrate (GABA) aminotransferase gene (gabT) is induced by GABA and highly expressed in bacteroids. | Microbiology (Reading, England) 20020201 |
Mitochondrial dysfunction associated with neuronal death following status epilepticus in rat. | Epilepsy research 20020201 |
Identification of the YMN-1 antigen protein and biochemical analyses of protein components in the mitochondrial nucleoid fraction of the yeast Saccharomyces cerevisiae. | Protoplasma 20020201 |
Metabolic compartmentation in cortical synaptosomes: influence of glucose and preferential incorporation of endogenous glutamate into GABA. | Neurochemical research 20020201 |
Structural basis of the dysfunctioning of human 2-oxo acid dehydrogenase complexes. | Current medicinal chemistry 20020201 |
Oxygen sensors and angiogenesis. | Seminars in cell & developmental biology 20020201 |
Plasma lysine concentration and availability of 2-ketoglutarate in liver mitochondria. | Journal of inherited metabolic disease 20020201 |
High-yield actinorhodin production in fed-batch culture by a Streptomyces lividans strain overexpressing the pathway-specific activator gene actll-ORF4. | Journal of industrial microbiology & biotechnology 20020201 |
Inhibition of aspartate aminotransferase by glycation in vitro under various conditions. | Journal of enzyme inhibition and medicinal chemistry 20020201 |
A large outbreak of Legionnaires' disease at a flower show, the Netherlands, 1999. | Emerging infectious diseases 20020101 |
Biosynthesis of anthraquinones in cell cultures of Cinchona 'Robusta' proceeds via the methylerythritol 4-phosphate pathway. | Phytochemistry 20020101 |
Glutamine: clinical applications and mechanisms of action. | Current opinion in clinical nutrition and metabolic care 20020101 |
Structure and mechanism of anthocyanidin synthase from Arabidopsis thaliana. | Structure (London, England : 1993) 20020101 |
Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities. | Journal of neurochemistry 20020101 |
Aminoadipate reductase gene: a new fungal-specific gene for comparative evolutionary analyses. | BMC evolutionary biology 20020101 |
Enzymatic amplification by substrate recycling for alpha-ketoglutarate in conjunction with capillary electrophoresis. | Journal of capillary electrophoresis and microchip technology 20020101 |
Essentiality of mitochondrial oxidative metabolism for photosynthesis: optimization of carbon assimilation and protection against photoinhibition. | Critical reviews in biochemistry and molecular biology 20020101 |
[Different therapeutic approaches for chronic diffuse liver lesions using ornicetil, lactulose, etimizol and corinfar]. | Likars'ka sprava 20020101 |
Gene discovery within the planctomycete division of the domain Bacteria using sequence tags from genomic DNA libraries. | Genome biology 20020101 |
[Biologic properties of lipoic acid]. | Postepy higieny i medycyny doswiadczalnej 20020101 |
Activity of enzymes involved in energy production in the small intestine during suckling-weaning transition of pigs. | Biology of the neonate 20020101 |
Regulation of the HIF pathway: enzymatic hydroxylation of a conserved prolyl residue in hypoxia-inducible factor alpha subunits governs capture by the pVHL E3 ubiquitin ligase complex. | Advances in enzyme regulation 20020101 |
[Metabolism of Yarrowia lipolytica grown on ethanol under conditions promoting the production of alpha-ketoglutaric and citric acids: a comparative study of the central metabolism enzymes]. | Mikrobiologiia 20020101 |
Molecular characterization of the renal organic anion transporter 1. | Cell biochemistry and biophysics 20020101 |
Effects of ornithine alpha-ketoglutarate on circulatory antioxidants and lipid peroxidation products in ammonium acetate treated rats. | Annals of nutrition & metabolism 20020101 |
The complex fate of alpha-ketoacids. | Annual review of plant biology 20020101 |
Effects of alpha-ketoglutarate on lipid peroxidation and antioxidant status during chronic ethanol administration in Wistar rats. | Polish journal of pharmacology 20020101 |
Regulation of the production of polygalacturonase by Aspergillus niger. | Folia microbiologica 20020101 |
Metabolic signaling between neurons and glial cells: a short review. | Journal of physiology, Paris 20020101 |
[Exogenous L-arginine modulates mitochondrial and microsomal oxidation in acute and intermittent normobaric hypoxia]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20020101 |
Selective identification of new therapeutic targets of Mycobacterium tuberculosis by IVIAT approach. | Tuberculosis (Edinburgh, Scotland) 20020101 |
Glucose metabolism, energetics, and function of rat hearts exposed to ischemic preconditioning and oxygenated cardioplegia. | Journal of cardiac surgery 20020101 |
Mitochondria in Alzheimer's disease. | International review of neurobiology 20020101 |
[A comparative study of the isocitrate dehydrogenases of Chlorobium limicola forma Chlorobium thiosulfatophilum and Rhodopseudomonas palustris]. | Mikrobiologiia 20020101 |
Heart-specific genes revealed by expressed sequence tag (EST) sampling. | Genome biology 20020101 |
The mitochondrial uncoupling proteins. | Genome biology 20020101 |
Oxygen-sensing mechanisms and the regulation of redox-responsive transcription factors in development and pathophysiology. | Respiratory research 20020101 |
[Mitochondria respiration in developing sunflower seeds]. | Izvestiia Akademii nauk. Seriia biologicheskaia 20020101 |
Transport of anionic drugs across the basolateral membrane of proximal S2 segments of the rabbit kidney. Inverse relationship between the affinity to the p-aminohippurate transport system and the transport rate. | Arzneimittel-Forschung 20020101 |
[Regulation of oxidative phosphorylation by liver mitochondria receptors after adaptation by rats to periodic normal pressure and acute hypoxia]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101 |
[Effect of tricarboxylic acid cycle intermediates on nitric oxide system during acute hypoxia]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101 |
Ammonia assimilation in Klebsiella pneumoniae F-5-2 that can utilize ammonium and nitrate ions simultaneously: purification and characterization of glutamate dehydrogenase and glutamine synthetase. | Journal of bioscience and bioengineering 20020101 |
The mitochondrial oxoglutarate carrier: cysteine-scanning mutagenesis of transmembrane domain IV and sensitivity of Cys mutants to sulfhydryl reagents. | Biochemistry 20011225 |
Glutamate decreases pyruvate carboxylase activity and spares glucose as energy substrate in cultured cerebellar astrocytes. | Journal of neuroscience research 20011215 |
Monitoring of alpha-ketoglutarate in a fermentation process using expanded bed enzyme reactors. | Biosensors & bioelectronics 20011201 |
Suramin inhibits respiration and induces membrane permeability transition in isolated rat liver mitochondria. | Toxicology 20011201 |
Structure of proline 3-hydroxylase. Evolution of the family of 2-oxoglutarate dependent oxygenases. | European journal of biochemistry 20011201 |
The acute effect of valproate on cerebral energy metabolism in mice. | Epilepsy research 20011201 |
Chemopreventive efficacy of selenium against N-nitrosodiethylamine-induced hepatoma in albino rats. | Cell biochemistry and function 20011201 |
Pyruvate carboxylation in neurons. | Journal of neuroscience research 20011201 |
Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain. | Journal of neuroscience research 20011201 |
Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy. | Journal of neuroscience research 20011201 |
Alternative oxidase in durum wheat mitochondria. Activation by pyruvate, hydroxypyruvate and glyoxylate and physiological role. | Plant & cell physiology 20011201 |
Expression of the 2,4-D degradative pathway of pJP4 in an alkaliphilic, moderately halophilic soda lake isolate, Halomonas sp. EF43. | Extremophiles : life under extreme conditions 20011201 |
Selective loss of KGDHC-enriched neurons in Alzheimer temporal cortex: does mitochondrial variation contribute to selective vulnerability? | Journal of molecular neuroscience : MN 20011201 |
[Study on the organic acids metabolism in Candida glycerolgenesis under different fermentation conditions]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20011201 |
A soybean plastid-targeted NADH-malate dehydrogenase: cloning and expression analyses. | American journal of botany 20011201 |
Effect of DL-alpha-lipoic acid on mitochondrial enzymes in aged rats. | Chemico-biological interactions 20011128 |
Effect of environmental and chemotactic stimuli on the activity of the Campylobacter jejuni flaA sigma(28) promoter. | FEMS microbiology letters 20011127 |
NADP-glutamate dehydrogenase isoenzymes of Saccharomyces cerevisiae. Purification, kinetic properties, and physiological roles. | The Journal of biological chemistry 20011123 |
Modelling mammary metabolism in the dairy cow to predict milk constituent yield, with emphasis on amino acid metabolism and milk protein production: model construction. | Journal of theoretical biology 20011121 |
Analysis of conformationally restricted alpha-ketoglutarate analogues as substrates of dehydrogenases and aminotransferases. | Analytical biochemistry 20011115 |
Mercapturic acids (N-acetylcysteine S-conjugates) as endogenous substrates for the renal organic anion transporter-1. | Molecular pharmacology 20011101 |
Crystallization and preliminary X-ray diffraction studies of monomeric isocitrate dehydrogenase by the MAD method using Mn atoms. | Acta crystallographica. Section D, Biological crystallography 20011101 |
Role of a highly conserved YPITP motif in 2-oxoacid:ferredoxin oxidoreductase: heterologous expression of the gene from Sulfolobus sp.strain 7, and characterization of the recombinant and variant enzymes. | European journal of biochemistry 20011101 |
Substrate-specific diffusion of select dicarboxylates through Chlamydia trachomatis PorB. | Microbiology (Reading, England) 20011101 |
Characterization of the ornithine aminotransferase from Plasmodium falciparum. | Molecular and biochemical parasitology 20011101 |
Perspectives on the biology of uncoupling protein (UCP) homologues. | Biochemical Society transactions 20011101 |
Modulation of TCA cycle enzymes and aluminum stress in Pseudomonas fluorescens. | Journal of inorganic biochemistry 20011101 |
The effect of high-intensity exhaustive exercise studied in isolated mitochondria from human skeletal muscle. | Pflugers Archiv : European journal of physiology 20011101 |
Mechanism of inhibition of lysyl hydroxylase activity by the organophosphates malathion and malaoxon. | Toxicology and applied pharmacology 20011101 |
Hydrogen-deuterium exchange at non-labile sites: a new reaction facet with broad implications for structural and dynamic determinations. | Journal of the American Society for Mass Spectrometry 20011101 |
H+-ATPase defect in Corynebacterium glutamicum abolishes glutamic acid production with enhancement of glucose consumption rate. | Applied microbiology and biotechnology 20011101 |
Cyanobacteria perceive nitrogen status by sensing intracellular 2-oxoglutarate levels. | The Journal of biological chemistry 20011012 |
The inhibition of gluconeogenesis by chloroquine contributes to its hypoglycaemic action. | European journal of pharmacology 20011012 |
A single gene produces mitochondrial, cytoplasmic, and peroxisomal NADP-dependent isocitrate dehydrogenase in Aspergillus nidulans. | The Journal of biological chemistry 20011005 |
Metabolic consequences of altered phosphoenolpyruvate carboxykinase activity in Corynebacterium glutamicum reveal anaplerotic regulation mechanisms in vivo. | Metabolic engineering 20011001 |
Contrasting fates for 6-alpha-methylpenicillin N upon oxidation by deacetoxycephalosporin C synthase (DAOCS) and deacetoxy/deacetylcephalosporin C synthase (DAOC/DACS). | Bioorganic & medicinal chemistry letters 20010917 |
Molecular and Biochemical Characterization of Rat epsilon -N-Trimethyllysine Hydroxylase, the First Enzyme of Carnitine Biosynthesis. | The Journal of biological chemistry 20010907 |
NMR indirect detection of glutamate to measure citric acid cycle flux in the isolated perfused mouse heart. | FEBS letters 20010907 |
The mechanism of action of bacimethrin, a naturally occurring thiamin antimetabolite. | Bioorganic & medicinal chemistry letters 20010903 |
Mechanism of increased renal gene expression during metabolic acidosis. | American journal of physiology. Renal physiology 20010901 |
Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. | American journal of physiology. Renal physiology 20010901 |
Structure-function analysis of phytanoyl-CoA 2-hydroxylase mutations causing Refsum's disease. | Human molecular genetics 20010901 |
Conversion of amino acids into aroma compounds by cell-free extracts of Lactobacillus helveticus. | Journal of applied microbiology 20010901 |
Effects of ADP on different inhibitory properties of brain glutamate dehydrogenase isoproteins by perphenazine. | Biochimie 20010901 |
Alteration of the specificity of malate dehydrogenase by chemical modulation of an active site arginine. | The Journal of biological chemistry 20010817 |
Investigations into biochemical changes due to diurnal variation and estrus cycle in female rats using high-resolution (1)H NMR spectroscopy of urine and pattern recognition. | Analytical biochemistry 20010815 |
Spectroscopic studies of substrate interactions with clavaminate synthase 2, a multifunctional alpha-KG-dependent non-heme iron enzyme: correlation with mechanisms and reactivities. | Journal of the American Chemical Society 20010801 |
Detection of antimitochondrial autoantibodies in immunofluorescent AMA-negative patients with primary biliary cirrhosis using recombinant autoantigens. | Hepatology (Baltimore, Md.) 20010801 |
Intrahepatic amino acid and glucose metabolism in a D-galactosamine-induced rat liver failure model. | Hepatology (Baltimore, Md.) 20010801 |
Lipoamide dehydrogenase from Corynebacterium glutamicum: molecular and physiological analysis of the lpd gene and characterization of the enzyme. | Microbiology (Reading, England) 20010801 |
Metabonomic investigations into hydrazine toxicity in the rat. | Chemical research in toxicology 20010801 |
Reaction mechanism from leucoanthocyanidin to anthocyanidin 3-glucoside, a key reaction for coloring in anthocyanin biosynthesis. | The Journal of biological chemistry 20010713 |
Gas chromatographic-mass spectrometric screening for organic acidemias using dried urine filter paper: determination of alpha-ketoacids. | Journal of chromatography. B, Biomedical sciences and applications 20010705 |
A mathematical model of compartmentalized neurotransmitter metabolism in the human brain. | American journal of physiology. Endocrinology and metabolism 20010701 |
Biochemical properties of porcine white adipose tissue mitochondria and relevance to fatty acid oxidation. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010701 |
Comparative in vitro bacteriostatic and bactericidal activity of trovafloxacin, levofloxacin and moxifloxacin against clinical and environmental isolates of Legionella spp. | International journal of antimicrobial agents 20010701 |
2-Oxoglutarate transport system in Staphylococcus aureus. | Archives of microbiology 20010701 |
Regulation of HIF by the von Hippel-Lindau tumour suppressor: implications for cellular oxygen sensing. | IUBMB life 20010701 |
Modulation of mitochondrial function by hydrogen peroxide. | The Journal of biological chemistry 20010629 |
Ammonium in nervous tissue: transport across cell membranes, fluxes from neurons to glial cells, and role in signalling. | Progress in neurobiology 20010601 |
Cassette mutagenesis of lysine 130 of human glutamate dehydrogenase. An essential residue in catalysis. | European journal of biochemistry 20010601 |
Energetic determinants of tyrosine phosphorylation of focal adhesion proteins during hypoxia/reoxygenation of kidney proximal tubules. | The American journal of pathology 20010601 |
Lactobacillus casei and Lactobacillus plantarum initiate catabolism of methionine by transamination. | Journal of applied microbiology 20010601 |
Lipoic acid metabolism in Arabidopsis thaliana: cloning and characterization of a cDNA encoding lipoyltransferase. | Plant & cell physiology 20010601 |
Molecular physiology of renal p-aminohippurate secretion. | News in physiological sciences : an international journal of physiology produced jointly by the International Union of Physiological Sciences and the American Physiological Society 20010601 |
Glutamine and alpha-ketoglutarate are metabolite signals involved in nitrate reductase gene transcription in untransformed and transformed tobacco plants deficient in ferredoxin-glutamine-alpha-ketoglutarate aminotransferase. | Planta 20010601 |
Resonance Raman studies of the iron(II)--alpha-keto acid chromophore in model and enzyme complexes. | Journal of the American Chemical Society 20010530 |
Alternative reactivity of an alpha-ketoglutarate-dependent iron(II) oxygenase: enzyme self-hydroxylation. | Journal of the American Chemical Society 20010530 |
Alteration of the co-substrate selectivity of deacetoxycephalosporin C synthase. The role of arginine 258. | The Journal of biological chemistry 20010525 |
Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS). | Journal of molecular biology 20010518 |
A GTP-dependent vertebrate-type phosphoenolpyruvate carboxykinase from Mycobacterium smegmatis. | The Journal of biological chemistry 20010511 |
Determination of the midpoint potential of the FAD and FMN flavin cofactors and of the 3Fe-4S cluster of glutamate synthase. | Biochemistry 20010508 |
Isolation of a family of organic anion transporters from human liver and kidney. | Biochemical and biophysical research communications 20010504 |
Cloning and functional characterization of a high-affinity Na(+)/dicarboxylate cotransporter from mouse brain. | American journal of physiology. Cell physiology 20010501 |
Inhibition of lysyl hydroxylase by malathion and malaoxon. | Toxicology and applied pharmacology 20010501 |
Protection by thiols of the mitochondrial complexes from 4-hydroxy-2-nonenal. | Free radical biology & medicine 20010501 |
13C isotopomer analysis of glucose and alanine metabolism reveals cytosolic pyruvate compartmentation as part of energy metabolism in astrocytes. | Glia 20010501 |
[Mitochondrial DNA T to G mutation 8993 in Leigh encephalopathy and organic aciduria]. | No to hattatsu = Brain and development 20010501 |
Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase. | Cellular and molecular life sciences : CMLS 20010501 |
Production of beta-thujaplicin in Cupressus lusitanica suspension cultures fed with organic acids and monoterpenes. | Bioscience, biotechnology, and biochemistry 20010501 |
[Effects of ammonia on cell metabolism in the culture of recombinant CHO cells]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20010501 |
Structures of Escherichia coli histidinol-phosphate aminotransferase and its complexes with histidinol-phosphate and N-(5'-phosphopyridoxyl)-L-glutamate: double substrate recognition of the enzyme. | Biochemistry 20010417 |
Recombinant tyrosine aminotransferase from Trypanosoma cruzi: structural characterization and site directed mutagenesis of a broad substrate specificity enzyme. | Biochimica et biophysica acta 20010407 |
Glutamine protects mitochondrial structure and function in oxygen toxicity. | American journal of physiology. Lung cellular and molecular physiology 20010401 |
Glutamine supplementation promotes anaplerosis but not oxidative energy delivery in human skeletal muscle. | American journal of physiology. Endocrinology and metabolism 20010401 |
The effects of endurance training and exhaustive exercise on mitochondrial enzymes in tissues of the rat (Rattus norvegicus). | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010401 |
Adenoviral gene transfer restores lysyl hydroxylase activity in type VI Ehlers-Danlos syndrome. | The Journal of investigative dermatology 20010401 |
Aspartate kinase 2. A candidate gene of a quantitative trait locus influencing free amino acid content in maize endosperm. | Plant physiology 20010401 |
Complete genomic structure of mouse lysyl hydroxylase 2 and lysyl hydroxylase 3/collagen glucosyltransferase. | Matrix biology : journal of the International Society for Matrix Biology 20010401 |
Increased levels of adenine nucleotides modify the interaction between starch synthesis and respiration when adenine is supplied to discs from growing potato tubers. | Planta 20010401 |
Uridylylation of the PII protein from Herbaspirillum seropedicae. | Canadian journal of microbiology 20010401 |
The genes for anabolic 2-oxoglutarate: ferredoxin oxidoreductase from Hydrogenobacter thermophilus TK-6. | Biochemical and biophysical research communications 20010330 |
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation. | Journal of molecular biology 20010323 |
Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location. | The Journal of biological chemistry 20010316 |
Potent cytolytic response by a CD8+ CTL clone to multiple peptides from the same protein in association with an allogeneic class I MHC molecule. | Journal of immunology (Baltimore, Md. : 1950) 20010301 |
Cloning and characterization of the gene encoding the glutamate dehydrogenase of Streptococcus suis serotype 2. | Clinical and diagnostic laboratory immunology 20010301 |
Development of a stable-isotope dilution assay for gamma-aminobutyric acid (GABA) transaminase in isolated leukocytes and evidence that GABA and beta-alanine transaminases are identical. | Clinical chemistry 20010301 |
Gene duplication in the diversification of secondary metabolism: tandem 2-oxoglutarate-dependent dioxygenases control glucosinolate biosynthesis in Arabidopsis. | The Plant cell 20010301 |
Regulation of skeletal muscle amino acid metabolism during exercise. | International journal of sport nutrition and exercise metabolism 20010301 |
Nitrogen shuttling between neurons and glial cells during glutamate synthesis. | Journal of neurochemistry 20010301 |
P-glycoprotein-mediated transport of digitoxin, alpha-methyldigoxin and beta-acetyldigoxin. | Naunyn-Schmiedeberg's archives of pharmacology 20010301 |
Protective effect of Ninjin-yoei-to on damage to isolated hepatocytes following transient exposure to tert-butyl hydroperoxide. | Japanese journal of pharmacology 20010301 |
Adenosine 5'-0-[S-(4-succinimidyl-benzophenone)thiophosphate]: a new photoaffinity label of the allosteric ADP site of bovine liver glutamate dehydrogenase. | Biochemistry 20010213 |
A novel syndrome affecting multiple mitochondrial functions, located by microcell-mediated transfer to chromosome 2p14-2p13. | American journal of human genetics 20010201 |
Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2. | Molecular pharmacology 20010201 |
Mitochondrial biogenesis during germination in maize embryos. | Plant physiology 20010201 |
Chronic lamotrigine treatment increases rat hippocampal GABA shunt activity and elevates cerebral taurine levels. | Epilepsy research 20010201 |
Spatial heterogeneity of energy turnover in the heart. | Pflugers Archiv : European journal of physiology 20010201 |
Inhibitory effect of glycation on catalytic activity of alanine aminotransferase. | Molecular and cellular biochemistry 20010201 |
[Effects of long-term physical training on age-related changes of energy transformation of mice heart mitochondria]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20010201 |
Mikimopine synthase (mis) gene on pRi1724. | Gene 20010124 |
Identification in Saccharomyces cerevisiae of two isoforms of a novel mitochondrial transporter for 2-oxoadipate and 2-oxoglutarate. | The Journal of biological chemistry 20010119 |
Expression of a cytoplasmic transhydrogenase in Saccharomyces cerevisiae results in formation of 2-oxoglutarate due to depletion of the NADPH pool. | Yeast (Chichester, England) 20010115 |
Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: contrast with the unique cold-induced mitochondrial carrier CGI-69. | The Biochemical journal 20010115 |
Recognition of the lipoyl domain is the ultimate determinant of substrate channelling in the pyruvate dehydrogenase multienzyme complex. | Journal of molecular biology 20010105 |
Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins. | The Journal of pharmacology and experimental therapeutics 20010101 |
Biosynthesis of menaquinone (vitamin K2) and ubiquinone (coenzyme Q): a perspective on enzymatic mechanisms. | Vitamins and hormones 20010101 |
Kynurenine aminotransferase I activity in human placenta. | Placenta 20010101 |
Contribution of glutamate dehydrogenase to mitochondrial glutamate metabolism studied by (13)C and (31)P nuclear magnetic resonance. | Journal of experimental botany 20010101 |
Glutamate dehydrogenase from liver of euthermic and hibernating Richardson's ground squirrels: evidence for two distinct enzyme forms. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20010101 |
The DNA-repair protein AlkB, EGL-9, and leprecan define new families of 2-oxoglutarate- and iron-dependent dioxygenases. | Genome biology 20010101 |
Diabetes-induced changes in retinal NAD-redox status: pharmacological modulation and implications for pathogenesis of diabetic retinopathy. | Pharmacology 20010101 |
Lysine metabolism in higher plants. | Amino acids 20010101 |
[Characteristics of NADP-dependent isocitrate dehydrogenase functioning in pea leaves during salt stress]. | Izvestiia Akademii nauk. Seriia biologicheskaia 20010101 |
Effects of scopoletin and aflatoxin B1 on bovine hepatic mitochondrial respiratory complexes, 2: a-ketoglutarate cytochrome c and succinate cytochrome c reductases. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101 |
[Metabolic characteristics of the Yarrowia lipolytica strain producing alpha-ketoglutaric and citric acids from ethanol and the effect of [NH4+] and [O2] on yeast respiration and biosynthesis]. | Mikrobiologiia 20010101 |
Glutamate synthesis via photoreduction of NADP+ by photostable chlorophyllide coupled with polyethylene-glycol. | Biotechnology and bioengineering 20010101 |
Tricarboxylic acid cycle enzymes of the ectomycorrhizal basidiomycete, Suillus bovinus. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101 |
No association between DLST gene and Alzheimer's disease or Wernicke-Korsakoff syndrome. | Neurobiology of aging 20010101 |
[New aerobic methyltrophic isolates from the Soda lakes of the southern Transbaikal]. | Mikrobiologiia 20010101 |
[State of mitochondrial respiration and calcium capacity in livers of rats with different resistance to hypoxia after injections of L-arginine]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20010101 |
Purification and characterization of aspartate aminotransferase from developing embryos of the camel tick Hyalomma dromedarii. | Experimental & applied acarology 20010101 |
[Alpha ketoglutarate dehydrogenase deficiency]. | Ryoikibetsu shokogun shirizu 20010101 |
[Disorders of pyruvate metabolism and TCA cycle]. | Ryoikibetsu shokogun shirizu 20010101 |
Effects of substrate structural analogues on the enzymatic activities of aspartate aminotransferase isoenzymes. | Journal of enzyme inhibition 20010101 |
PKA, PKC, and AKAP localization in and around the neuromuscular junction. | BMC neuroscience 20010101 |
Analysis of CHO cells metabolic redistribution in a glutamate-based defined medium in continuous culture. | Biotechnology progress 20010101 |
Acute toxicity studies of alpha-ketoglutarate: a promising antidote for cyanide poisoning. | Journal of applied toxicology : JAT 20010101 |
[The role of hyperlactatedehydrogenasemia in induction of metabolic disorders in the body]. | Voprosy meditsinskoi khimii 20010101 |
Oxidative metabolites of 5-S-cysteinyldopamine inhibit the pyruvate dehydrogenase complex. | Journal of neural transmission (Vienna, Austria : 1996) 20010101 |
Influence on Enterobacter cloacae metabolism, cell-surface hydrophobicity and motility of suprainhibitory concentrations of carbapenems. | Folia microbiologica 20010101 |
The future of nutrition and wound healing. | Journal of tissue viability 20010101 |
[Effect of L-arginine and the nitric oxide synthase blocker L-NNA on calcium capacity in rat liver mitochondria with differing resistance to hypoxia]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101 |
[Effect of L-arginine and N(omega)-nitro-L-arginine on oxidative phosphorylation and lipid peroxidation in rats with various tolerance to hypoxia under stressful conditions]. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101 |
Inhibition of glutamine transport in rat brain mitochondria by some amino acids and tricarboxylic acid cycle intermediates. | Neurochemical research 19990701 |
Biosynthesis of o-succinylbenzoic acid. I: Cell free synthesis of o-succinylbenzoic acid from isochorismic acid in enzyme preparations from vitamin K producing bacteria. | Archives of biochemistry and biophysics 19870701 |