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Home Other Building Blocks Mlr-1023

Mlr-1023

CAS No.:
41964-07-2
Catalog Number:
AG00C9PY
Molecular Formula:
C11H10N2O2
Molecular Weight:
202.2093
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
≥95%
1 week
United States
$112
- +
10mg
≥95%
1 week
United States
$157
- +
25mg
≥95%
1 week
United States
$293
- +
50mg
≥95%
1 week
United States
$446
- +
Product Description
Catalog Number:
AG00C9PY
Chemical Name:
Mlr-1023
CAS Number:
41964-07-2
Molecular Formula:
C11H10N2O2
Molecular Weight:
202.2093
MDL Number:
MFCD00866900
IUPAC Name:
5-(3-methylphenoxy)-1H-pyrimidin-2-one
InChI:
InChI=1S/C11H10N2O2/c1-8-3-2-4-9(5-8)15-10-6-12-11(14)13-7-10/h2-7H,1H3,(H,12,13,14)
InChI Key:
HJQILFPVRNHTIG-UHFFFAOYSA-N
SMILES:
Cc1cccc(c1)Oc1cnc(=O)[nH]c1
UNII:
MU3JD8E9IS
NSC Number:
314335
Properties
Complexity:
310  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
202.074g/mol
Formal Charge:
0
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
202.213g/mol
Monoisotopic Mass:
202.074g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
50.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.4  
Literature
Title Journal
The Lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose homeostasis in animal models of type 2 diabetes. The Journal of pharmacology and experimental therapeutics 20120701
MLR-1023 is a potent and selective allosteric activator of Lyn kinase in vitro that improves glucose tolerance in vivo. The Journal of pharmacology and experimental therapeutics 20120701
Properties