Home Other Building Blocks JNJ 5207852 dihydrochloride

JNJ 5207852 dihydrochloride

CAS No.:
398473-34-2
Catalog Number:
AG00C9HD
Molecular Formula:
C20H32N2O
Molecular Weight:
316.4809
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
≥98%
1 week
United States
$157
- +
10mg
≥98%
1 week
United States
$247
- +
250mg
95%
1 week
United States
$450
- +
1g
95%
1 week
United States
$1071
- +
Product Description
Catalog Number:
AG00C9HD
Chemical Name:
JNJ 5207852 dihydrochloride
CAS Number:
398473-34-2
Molecular Formula:
C20H32N2O
Molecular Weight:
316.4809
MDL Number:
MFCD05974930
IUPAC Name:
1-[3-[4-(piperidin-1-ylmethyl)phenoxy]propyl]piperidine
InChI:
InChI=1S/C20H32N2O/c1-3-12-21(13-4-1)16-7-17-23-20-10-8-19(9-11-20)18-22-14-5-2-6-15-22/h8-11H,1-7,12-18H2
InChI Key:
PTKHFRNHJULJKT-UHFFFAOYSA-N
SMILES:
C1CCN(CC1)CCCOc1ccc(cc1)CN1CCCCC1
UNII:
4I9OVB1G7D
Properties
Complexity:
303  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
316.251g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
316.489g/mol
Monoisotopic Mass:
316.251g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
15.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.8  
Literature
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4-[6-(2-Aminoethyl)naphthalen-2-yl]benzonitriles are potent histamine H3 receptor antagonists with high CNS penetration. Bioorganic & medicinal chemistry letters 20070301
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
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4-phenoxypiperidines: potent, conformationally restricted, non-imidazole histamine H3 antagonists. Journal of medicinal chemistry 20050324
2-(4-alkylpiperazin-1-yl)quinolines as a new class of imidazole-free histamine H3 receptor antagonists. Journal of medicinal chemistry 20050113
Acute wake-promoting actions of JNJ-5207852, a novel, diamine-based H3 antagonist. British journal of pharmacology 20041101
A new class of diamine-based human histamine H3 receptor antagonists: 4-(aminoalkoxy)benzylamines. Journal of medicinal chemistry 20030828
Properties