(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-3-oxo-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid
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Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids. | Molecular pharmacology 20150301 |
Metabolic characteristics of 13-cis-retinoic acid (isotretinoin) and anti-tumour activity of the 13-cis-retinoic acid metabolite 4-oxo-13-cis-retinoic acid in neuroblastoma. | British journal of pharmacology 20141201 |
Detection of retinoic acid receptor agonistic activity and identification of causative compounds in municipal wastewater treatment plants in Japan. | Environmental toxicology and chemistry 20120901 |
Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans. | Drug metabolism and disposition: the biological fate of chemicals 20100701 |
Metabolism and regulation of gene expression by 4-oxoretinol versus all-trans retinoic acid in normal human mammary epithelial cells. | Journal of cellular physiology 20090901 |
The metabolism and pharmacokinetics of isotretinoin in patients with acne and rosacea are not influenced by ethanol. | The British journal of dermatology 20090901 |
Sequential RARbeta and alpha signalling in vivo can induce adult forebrain neural progenitor cells to differentiate into neurons through Shh and FGF signalling pathways. | Developmental biology 20090215 |
The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system. | Pharmacogenetics and genomics 20070301 |
Beta-carotene and apocarotenals promote retinoid signaling in BEAS-2B human bronchioepithelial cells. | Archives of biochemistry and biophysics 20061101 |
Retinoids have differing efficacies on alveolar regeneration in a dexamethasone-treated mouse. | American journal of respiratory cell and molecular biology 20060801 |
A novel cytochrome P450, zebrafish Cyp26D1, is involved in metabolism of all-trans retinoic acid. | Molecular endocrinology (Baltimore, Md.) 20060701 |
Method to determine 4-oxo-retinoic acids, retinoic acids and retinol in serum and cell extracts by liquid chromatography/diode-array detection atmospheric pressure chemical ionisation tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20060101 |
The control of morphogen signalling: regulation of the synthesis and catabolism of retinoic acid in the developing embryo. | Developmental biology 20050901 |
Retinoic acid and its 4-oxo metabolites are functionally active in human skin cells in vitro. | The Journal of investigative dermatology 20050701 |
Discovery of new tetracyclic tetrahydrofuran derivatives as potential broad-spectrum psychotropic agents. | Journal of medicinal chemistry 20050324 |
All-trans retinoic acid is a ligand for the orphan nuclear receptor ROR beta. | Nature structural biology 20031001 |
Homozygous deletion of the CRABPI gene in AB1 embryonic stem cells results in increased CRABPII gene expression and decreased intracellular retinoic acid concentration. | Archives of biochemistry and biophysics 20030315 |
HPLC-MS/MS analysis of the products generated from all-trans-retinoic acid using recombinant human CYP26A. | Journal of lipid research 20020701 |
Retinol metabolism and lecithin:retinol acyltransferase levels are reduced in cultured human prostate cancer cells and tissue specimens. | Cancer research 20020315 |
Reduced levels of retinyl esters and vitamin A in human renal cancers. | Cancer research 20010315 |
Granulocytic differentiation of human NB4 promyelocytic leukemia cells induced by all-trans retinoic acid metabolites. | Cancer research 20010115 |
Ethanol enhances retinoic acid metabolism into polar metabolites in rat liver via induction of cytochrome P4502E1. | Gastroenterology 20010101 |
Identification of human cytochrome P450 isoforms that contribute to all-trans-retinoic acid 4-hydroxylation. | Biochemical pharmacology 20000815 |
Initial retinoid requirement for early avian development coincides with retinoid receptor coexpression in the precardiac fields and induction of normal cardiovascular development. | Developmental dynamics : an official publication of the American Association of Anatomists 19981001 |
Generation of radical oxygen species by neural crest cells treated in vitro with isotretinoin and 4-oxo-isotretinoin. | Journal of craniofacial genetics and developmental biology 19900101 |