5-(3-Methyltriaz-1-en-1-yl)-1H-imidazole-4-carboxamide
| Title | Journal |
|---|---|
| The use of temozolomide for the treatment of malignant tumors: clinical evidence and molecular mechanisms of action. | Recent patents on anti-cancer drug discovery 20101101 |
| Evaluation of the exposure equivalence of oral versus intravenous temozolomide. | Cancer chemotherapy and pharmacology 20100301 |
| Temozolomide: The evidence for its therapeutic efficacy in malignant astrocytomas. | Core evidence 20090101 |
| TMZ-BioShuttle--a reformulated temozolomide. | International journal of medical sciences 20080101 |
| Treatment of glioblastoma multiforme cells with temozolomide-BioShuttle ligated by the inverse Diels-Alder ligation chemistry. | Drug design, development and therapy 20080101 |
| Pharmacokinetic study of temozolomide on a daily-for-5-days schedule in Japanese patients with relapsed malignant gliomas: first study in Asians. | International journal of clinical oncology 20071001 |
| Role of temozolomide in pediatric brain tumors. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20060701 |
| Development of a pharmacokinetic limited sampling model for temozolomide and its active metabolite MTIC. | Cancer chemotherapy and pharmacology 20050501 |
| Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations. | British journal of cancer 20050328 |
| Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98). | Cancer 20050101 |
| Disposition and pharmacokinetics of temozolomide in rat. | Xenobiotica; the fate of foreign compounds in biological systems 20040501 |
| Temozolomide in patients with advanced cancer: phase I and pharmacokinetic study. | Pharmacotherapy 20040101 |
| Dexamethasone protected human glioblastoma U87MG cells from temozolomide induced apoptosis by maintaining Bax:Bcl-2 ratio and preventing proteolytic activities. | Molecular cancer 20040101 |
| Population pharmacokinetics of temozolomide and metabolites in infants and children with primary central nervous system tumors. | Cancer chemotherapy and pharmacology 20031201 |
| Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids. | British journal of cancer 20030210 |
| Role of cytochrome P450 isoenzymes in metabolism of O(6)-benzylguanine: implications for dacarbazine activation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011201 |
| Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesis inhibitor TNP-470. | Cancer research 20010715 |
| Validated high-performance liquid chromatographic assay for simultaneous determination of dacarbazine and the plasma metabolites 5-(3-hydroxymethyl-3-methyl-1-triazeno)imidazole-4-carboxamide and 5-(3-methyl-1-triazeno)imidazole-4-carboxamide. | Journal of chromatography. B, Biomedical sciences and applications 20010415 |
| Design of a chimeric 3-methyl-1,2,3-triazene with mixed receptor tyrosine kinase and DNA damaging properties: a novel tumor targeting strategy. | The Journal of pharmacology and experimental therapeutics 20010301 |
| Carcinogenicity of the antineoplastic agent, 5-(3,3-dimethyl-1-triazeno)-imidazole-4-carboxamide, and its metabolites in rats. | Journal of the National Cancer Institute 19750401 |