2-HYDROXYESTRONE
Title | Journal |
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Red Clover Aryl Hydrocarbon Receptor (AhR) and Estrogen Receptor (ER) Agonists Enhance Genotoxic Estrogen Metabolism. | Chemical research in toxicology 20171120 |
The relation of urinary estrogen metabolites with mammographic densities in premenopausal women. | Cancer epidemiology 20121001 |
Antiproliferative effect of normal and 13-epi-D-homoestrone and their 3-methyl ethers on human reproductive cancer cell lines. | The Journal of steroid biochemistry and molecular biology 20121001 |
Association between physical activity and urinary estrogens and estrogen metabolites in premenopausal women. | The Journal of clinical endocrinology and metabolism 20121001 |
Urinary estrogen metabolites in two soy trials with premenopausal women. | European journal of clinical nutrition 20120901 |
Urinary estrogen metabolites during a randomized soy trial. | Nutrition and cancer 20120201 |
Anti-proliferative effects of Chinese herb Cornus officinalis in a cell culture model for estrogen receptor-positive clinical breast cancer. | Molecular medicine reports 20120101 |
BMPR2 expression is suppressed by signaling through the estrogen receptor. | Biology of sex differences 20120101 |
Sarcopenia and age-related endocrine function. | International journal of endocrinology 20120101 |
The role of diet and physical activity in breast, colorectal, and prostate cancer survivorship: a review of the literature. | British journal of cancer 20111108 |
Postmenopausal circulating levels of 2- and 16α-hydroxyestrone and risk of endometrial cancer. | British journal of cancer 20111025 |
Estrogen metabolites in the release of inflammatory mediators from human amnion-derived cells. | Life sciences 20110314 |
Dietary phenethyl isothiocyanate alters gene expression in human breast cancer cells. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Estrogen metabolite ratio: Is the 2-hydroxyestrone to 16α-hydroxyestrone ratio predictive for breast cancer? | International journal of women's health 20110101 |
Coffee consumption and risk of cancers: a meta-analysis of cohort studies. | BMC cancer 20110101 |
A preliminary study of the effectiveness of chinese therapeutic food on regulating female reproductive hormones. | Integrative medicine insights 20110101 |
The role of female hormones on lung function in chronic lung diseases. | BMC women's health 20110101 |
Adipocyte-derived factor as a modulator of oxidative estrogen metabolism: implications for obesity and estrogen-dependent breast cancer. | In vivo (Athens, Greece) 20110101 |
Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma. | BMC cancer 20110101 |
The manner in which calories are restricted impacts mammary tumor cancer prevention. | Journal of carcinogenesis 20110101 |
Serum concentrations of selected endogenous estrogen and estrogen metabolites in pre- and post-menopausal Chinese women with osteoarthritis. | Journal of endocrinological investigation 20101001 |
A new approach to measuring estrogen exposure and metabolism in epidemiologic studies. | The Journal of steroid biochemistry and molecular biology 20100801 |
Active, but not passive cigarette smoking was inversely associated with mammographic density. | Cancer causes & control : CCC 20100201 |
Comparison of liquid chromatography-tandem mass spectrometry, RIA, and ELISA methods for measurement of urinary estrogens. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100101 |
Effect of flaxseed consumption on urinary levels of estrogen metabolites in postmenopausal women. | Nutrition and cancer 20100101 |
The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo. | BMC medicine 20100101 |
Comparison of estrogens and estrogen metabolites in human breast tissue and urine. | Reproductive biology and endocrinology : RB&E 20100101 |
Executive functions and selective attention are favored in middle-aged healthy women carriers of the Val/Val genotype of the catechol-o-methyltransferase gene: a behavioral genetic study. | Behavioral and brain functions : BBF 20100101 |
Effects of a breast-health herbal formula supplement on estrogen metabolism in pre- and post-menopausal women not taking hormonal contraceptives or supplements: a randomized controlled trial. | Breast cancer : basic and clinical research 20100101 |
Urinary estrogen metabolites in women at high risk for breast cancer. | Carcinogenesis 20090901 |
Circulating estrogen metabolites and risk for breast cancer in premenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090801 |
Ethnicity, body size, and estrogen levels in postmenopausal Hispanic and non-Hispanic white women. | Journal of women's health (2002) 20090401 |
Lycium barbarum inhibits growth of estrogen receptor positive human breast cancer cells by favorably altering estradiol metabolism. | Nutrition and cancer 20090101 |
Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women. | Breast cancer research : BCR 20090101 |
Osteoarthritis associated with estrogen deficiency. | Arthritis research & therapy 20090101 |
Urinary estrogen metabolites and prostate cancer: a case-control study and meta-analysis. | Journal of experimental & clinical cancer research : CR 20090101 |
Daidzein-metabolizing phenotypes in relation to serum hormones and sex hormone binding globulin, and urinary estrogen metabolites in premenopausal women in the United States. | Cancer causes & control : CCC 20081201 |
A liquid chromatography-mass spectrometry method for the simultaneous measurement of 15 urinary estrogens and estrogen metabolites: assay reproducibility and interindividual variability. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081201 |
Coffee intake and CYP1A2*1F genotype predict breast volume in young women: implications for breast cancer. | British journal of cancer 20081104 |
Fat/fiber intakes and sex hormones in healthy premenopausal women in USA. | The Journal of steroid biochemistry and molecular biology 20081101 |
Levels of sex steroid and cardiovascular disease measures in premenopausal and hormone-treated women at midlife: implications for the 'timing hypothesis'. | Archives of internal medicine 20081027 |
Past oral contraceptive use and current dietary soy isoflavones influence estrogen metabolism in postmenopausal monkeys (Macaca fascicularis). | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081001 |
Oestrogen metabolites in relation to isoprostanes as a measure of oxidative stress. | Clinical endocrinology 20080501 |
Contribution of alpha2-adrenoceptors to the mitogenic effect of catecholestrogen in human breast cancer MCF-7 cells. | The Journal of steroid biochemistry and molecular biology 20080501 |
Coffee consumption and CYP1A2*1F genotype modify age at breast cancer diagnosis and estrogen receptor status. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080401 |
Phytoestrogens and breast cancer prevention: possible mechanisms of action. | Environmental health perspectives 20080401 |
Hydroxylated estrogen metabolites influence the proliferation of cultured human monocytes: possible role in synovial tissue hyperplasia. | Clinical and experimental rheumatology 20080101 |
The influence of menstrual risk factors on tumor characteristics and survival in postmenopausal breast cancer. | Breast cancer research : BCR 20080101 |
Recurrent Respiratory Papillomatosis (RRP)-Juvenile Onset. | Clinical medicine. Oncology 20080101 |
Treatment with an inhibitor of catechol-O-methyltransferase activity reduces preterm birth and impedes cervical resistance to stretch in pregnant rats. | Reproduction (Cambridge, England) 20071201 |
HPLC for stress-free screening of potential prostate cancer marker catechol estrogens in urine using a diamond-electrode electrochemical and a fluorescence detector. | Journal of separation science 20070901 |
Development of a nanomechanical biosensor for analysis of endocrine disrupting chemicals. | Lab on a chip 20070901 |
A pilot and feasibility study on the effects of naturopathic botanical and dietary interventions on sex steroid hormone metabolism in premenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070801 |
The effects of soygerm extracts on blood lipoproteins, antioxidative capacity and urinary estrogen metabolites in postmenopausal women on hormone therapy. | International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20070701 |
Soy isoflavonoid effects on endogenous estrogen metabolism in postmenopausal female monkeys. | Carcinogenesis 20070401 |
Estrogen metabolism modulates bone density in men. | Calcified tissue international 20070401 |
Effects of aerobic exercise training on estrogen metabolism in premenopausal women: a randomized controlled trial. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070401 |
Urinary phytoestrogen excretion of rats bearing methylnitrosourea-induced mammary carcinoma in response to treatment with 2-methoxyestradiol. | The Journal of steroid biochemistry and molecular biology 20070201 |
Changes in 2-hydroxyestrone and 16alpha-hydroxyestrone metabolism with flaxseed consumption: modification by COMT and CYP1B1 genotype. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070201 |
Soy isoflavone intake and estrogen excretion patterns in young women: effect of probiotic administration. | In vivo (Athens, Greece) 20070101 |
Analysis of change. | Methods in molecular biology (Clifton, N.J.) 20070101 |
Moderate coffee and alcohol consumption improves the estrogen metabolite profile in adjuvant treated breast cancer patients: a pilot study comparing pre- and post-operative levels. | Molecular genetics and metabolism 20061201 |
Quantitative structure-activity relationship of various endogenous estrogen metabolites for human estrogen receptor alpha and beta subtypes: Insights into the structural determinants favoring a differential subtype binding. | Endocrinology 20060901 |
CYP1A1 and CYP1B1 polymorphisms and their association with estradiol and estrogen metabolites in women who are premenopausal and perimenopausal. | The American journal of medicine 20060901 |
Estradiol and its metabolites and their association with knee osteoarthritis. | Arthritis and rheumatism 20060801 |
Selected diet and lifestyle factors are associated with estrogen metabolites in a multiracial/ethnic population of women. | The Journal of nutrition 20060601 |
A hormonal association between estrogen metabolism and proliferative thyroid disease. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20060601 |
Effects of docosahexaenoic acid supplementation on blood lipids, estrogen metabolism, and in vivo oxidative stress in postmenopausal vegetarian women. | European journal of clinical nutrition 20060301 |
Estrogen metabolites and systolic blood pressure in a population-based sample of postmenopausal women. | The Journal of clinical endocrinology and metabolism 20060301 |
Analysis of fifteen estrogen metabolites using packed column supercritical fluid chromatography-mass spectrometry. | Analytical chemistry 20060301 |
Role of polymorphic human cytochrome P450 enzymes in estrone oxidation. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060301 |
Comparison of plasma and urinary levels of 2-hydroxyestrogen and 16 alpha-hydroxyestrogen metabolites. | Molecular genetics and metabolism 20060201 |
Estrogen metabolism and breast cancer. | Epidemiology (Cambridge, Mass.) 20060101 |
Multilocus analysis of SNP and metabolic data within a given pathway. | BMC genomics 20060101 |
A randomized phase II trial of indole-3-carbinol in the treatment of vulvar intraepithelial neoplasia. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101 |
The relationship between physical activity and 2-hydroxyestrone, 16alpha-hydroxyestrone, and the 2/16 ratio in premenopausal women (United States). | Cancer causes & control : CCC 20050501 |
Associations between aerobic fitness and estrogen metabolites in premenopausal women. | Medicine and science in sports and exercise 20050401 |
CYP17 5'-UTR MspA1 polymorphism and the risk of premenopausal breast cancer in a German population-based case-control study. | Breast cancer research : BCR 20050101 |
Clinical effects of a proprietary combination isoflavone nutritional supplement in menopausal women: a pilot trial. | Alternative therapies in health and medicine 20050101 |
A common CYP1B1 polymorphism is associated with 2-OHE1/16-OHE1 urinary estrone ratio. | Clinical chemistry and laboratory medicine 20050101 |
Androgen conversion in osteoarthritis and rheumatoid arthritis synoviocytes--androstenedione and testosterone inhibit estrogen formation and favor production of more potent 5alpha-reduced androgens. | Arthritis research & therapy 20050101 |
Urinary estrogen metabolites, prostate specific antigen, and body mass index among African-American men in South Carolina. | Cancer detection and prevention 20050101 |
Effects of dioxin on metabolism of estrogens in waste incinerator workers. | Archives of environmental & occupational health 20050101 |
The oxidative metabolism of estrogen modulates response to ERT/HRT in postmenopausal women. | Bone 20040901 |
Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation. | The Journal of biological chemistry 20040702 |
The unusual binding properties of the third distinct teleost estrogen receptor subtype ERbetaa are accompanied by highly conserved amino acid changes in the ligand binding domain. | Endocrinology 20040601 |
Physical activity, body size, and estrogen metabolism in women. | Cancer causes & control : CCC 20040601 |
Effects of a moderate intensity exercise intervention on estrogen metabolism in postmenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040501 |
Serum steroid hormones, sex hormone-binding globulin concentrations, and urinary hydroxylated estrogen metabolites in post-menopausal women in relation to daidzein-metabolizing phenotypes. | The Journal of steroid biochemistry and molecular biology 20040401 |
High levels of oxidative DNA damage in lymphocyte DNA of premenopausal breast cancer patients from Egypt. | International journal of environmental health research 20040401 |
Patients with rheumatoid arthritis and systemic lupus erythematosus have increased renal excretion of mitogenic estrogens in relation to endogenous antiestrogens. | The Journal of rheumatology 20040301 |
Structural and stereoisomer effects of model estrogen quinone-derived DNA adducts: N6-(2-hydroxyestron-6(alpha,beta)-yl)-2'-deoxyadenosine and N2-(2-hydroxyestron-6(alpha,beta)-yl)-2'-deoxyguanosine. | Chemical research in toxicology 20040301 |
Endogenous estradiol metabolism during treatment with oral contraceptives. | International journal of clinical pharmacology and therapeutics 20040301 |
Association of CYP17, CYP19, CYP1B1, and COMT polymorphisms with serum and urinary sex hormone concentrations in postmenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040101 |
Phyto-oestrogens and breast cancer chemoprevention. | Breast cancer research : BCR 20040101 |
Cytochrome P450 1A2 (CYP1A2) activity, mammographic density, and oxidative stress: a cross-sectional study. | Breast cancer research : BCR 20040101 |
Cytochrome P450 1A2 (CYP1A2) activity and risk factors for breast cancer: a cross-sectional study. | Breast cancer research : BCR 20040101 |
Nutrition and cancer: a review of the evidence for an anti-cancer diet. | Nutrition journal 20040101 |
Pilot study: effect of 3,3'-diindolylmethane supplements on urinary hormone metabolites in postmenopausal women with a history of early-stage breast cancer. | Nutrition and cancer 20040101 |
Estrogen metabolites and the risk of breast cancer in older women. | Epidemiology (Cambridge, Mass.) 20031101 |
[Estrogen-dependent neoplasia - what is the significance of estradiol metabolites]. | Zentralblatt fur Gynakologie 20031101 |
Characterization of the oxidative metabolites of 17beta-estradiol and estrone formed by 15 selectively expressed human cytochrome p450 isoforms. | Endocrinology 20030801 |
Urinary equol excretion in relation to 2-hydroxyestrone and 16alpha-hydroxyestrone concentrations: an observational study of young to middle-aged women. | The Journal of steroid biochemistry and molecular biology 20030701 |
Influence of postmenopausal hormone replacement therapy on an estrogen metabolite biomarker of risk for breast cancer. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030601 |
Predictors of the plasma ratio of 2-hydroxyestrone to 16alpha-hydroxyestrone among pre-menopausal, nulliparous women from four ethnic groups. | Carcinogenesis 20030501 |
Endogenous estradiol metabolites stimulate the in vitro proliferation of human osteoblastic cells. | International journal of clinical pharmacology and therapeutics 20030401 |
A preliminary study of the effect of fluoxetine treatment on the 2:16-alpha-hydroxyestrone ratio in young women. | Therapeutic drug monitoring 20030201 |
Urinary estrogen metabolites and breast cancer: differential pattern of risk found with pre- versus post-treatment collection. | Steroids 20030101 |
Growth-inhibitory effects of the chemopreventive agent indole-3-carbinol are increased in combination with the polyamine putrescine in the SW480 colon tumour cell line. | BMC cancer 20030101 |
Reproducibility over time of measurements of androgens, estrogens and hydroxy estrogens in urine samples from post-menopausal women. | European journal of epidemiology 20030101 |
Urinary estrogen metabolites and prostate cancer: a case-control study in the United States. | Cancer causes & control : CCC 20021201 |
Stable isotope dilution high-performance liquid chromatography-electrospray ionization mass spectrometry method for endogenous 2- and 4-hydroxyestrones in human urine. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021125 |
Impact of hormone replacement therapy on endogenous estradiol metabolism in postmenopausal women. | Maturitas 20021025 |
Estradiol metabolism and malignant disease. | Maturitas 20020930 |
Catechol estrogen formation in liver microsomes from female ACI and Sprague-Dawley rats: comparison of 2- and 4-hydroxylation revisited. | Carcinogenesis 20020801 |
Stimulatory effect of cigarette smoking on the 15 alpha-hydroxylation of estradiol by human term placenta. | Clinical pharmacology and therapeutics 20020501 |
Estrogen metabolism and the diet-cancer connection: rationale for assessing the ratio of urinary hydroxylated estrogen metabolites. | Alternative medicine review : a journal of clinical therapeutic 20020401 |
Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and family history of breast cancer in premenopausal women. | Breast cancer research and treatment 20020301 |
The effects of postmenopausal hormone replacement therapy and oral contraceptives on the endogenous estradiol metabolism. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20011201 |
The ability of four catechol estrogens of 17beta-estradiol and estrone to induce DNA adducts in Syrian hamster embryo fibroblasts. | Carcinogenesis 20010901 |
Tissue-selective effects of continuous release of 2-hydroxyestrone and 16alpha-hydroxyestrone on bone, uterus and mammary gland in ovariectomized growing rats. | The Journal of endocrinology 20010701 |
Urinary estrogen metabolites and mammographic parenchymal patterns in postmenopausal women. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010601 |
Isolation and characterization of the monkey UDP-glucuronosyltransferase cDNA clone monUGT1A01 active on bilirubin and estrogens. | The Journal of steroid biochemistry and molecular biology 20010601 |
Risk reduction for DDT toxicity and carcinogenesis through dietary modification. | The journal of the Royal Society for the Promotion of Health 20010601 |
In vitro generation of peroxynitrite by 2- and 4-hydroxyestrogens in the presence of nitric oxide. | Chemical research in toxicology 20010501 |
Urinary excretion pattern of catecholestrogens in preovulatory LH surge during the 4-day estrous cycle of rats. | Journal of endocrinological investigation 20010501 |
Re: CYP17 promoter polymorphism and breast cancer in Australian women under age forty years. | Journal of the National Cancer Institute 20010404 |
Mutagenic properties of estrogen quinone-derived DNA adducts in simian kidney cells. | Biochemistry 20010109 |
Evaluation of an EIA method for measuring serum levels of the estrogen metabolite 2-hydroxyestrone in adults. | Steroids 20010101 |
Involvement of genotoxic effects in the initiation of estrogen-induced cellular transformation: studies using Syrian hamster embryo cells treated with 17beta-estradiol and eight of its metabolites. | International journal of cancer 20000401 |
Increased urinary excretion of 2-hydroxyestrone but not 16alpha-hydroxyestrone in premenopausal women during a soya diet containing isoflavones. | Cancer research 20000301 |
Estrogenic and antiestrogenic activities of 16alpha- and 2-hydroxy metabolites of 17beta-estradiol in MCF-7 and T47D human breast cancer cells. | The Journal of steroid biochemistry and molecular biology 19981201 |
Stable expression of a human liver UDP-glucuronosyltransferase (UGT2B15) with activity toward steroid and xenobiotic substrates. | Drug metabolism and disposition: the biological fate of chemicals 19940101 |
Absence of a suppressive effect of 2-hydroxyestrone on hyperprolactinemia in patients with prolactinomas before and after estradiol administration. | The Journal of clinical endocrinology and metabolism 19830201 |
2-hydroxyestrone: a new metabolite of estradiol in man. | Archives of biochemistry and biophysics 19601001 |