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Dz2002

CAS No.:
33231-14-0
Catalog Number:
AG00C6IW
Molecular Formula:
C10H13N5O3
Molecular Weight:
251.2419
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%
1 week
United States
$640
- +
10mg
98%
1 week
United States
$890
- +
50mg
98%
1 week
United States
$2557
- +
100mg
98%
1 week
United States
$3557
- +
Product Description
Catalog Number:
AG00C6IW
Chemical Name:
Dz2002
CAS Number:
33231-14-0
Molecular Formula:
C10H13N5O3
Molecular Weight:
251.2419
MDL Number:
MFCD28385844
IUPAC Name:
methyl 4-(6-aminopurin-9-yl)-2-hydroxybutanoate
InChI:
InChI=1S/C10H13N5O3/c1-18-10(17)6(16)2-3-15-5-14-7-8(11)12-4-13-9(7)15/h4-6,16H,2-3H2,1H3,(H2,11,12,13)
InChI Key:
HNKGMGPCSSJYOT-UHFFFAOYSA-N
SMILES:
COC(=O)C(CCn1cnc2c1ncnc2N)O
Properties
Complexity:
303  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
251.102g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
251.246g/mol
Monoisotopic Mass:
251.102g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
116A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.5  
Literature
Title Journal
An endogenously anti-inflammatory role for methylation in mucosal inflammation identified through metabolite profiling. Journal of immunology (Baltimore, Md. : 1950) 20110601
AdoHcy hydrolase of Trichomonas vaginalis: studies of the effects of 5'-modified adenosine analogues and related 6-N-cyclopropyl derivatives. Bioorganic & medicinal chemistry letters 20101215
Synthesis and biological evaluation of immunosuppressive agent DZ2002 and its stereoisomers. Bioorganic & medicinal chemistry 20081015
Inhibition of transmethylation down-regulates CD4 T cell activation and curtails development of autoimmunity in a model system. Journal of immunology (Baltimore, Md. : 1950) 20070415
A reversible S-adenosyl-L-homocysteine hydrolase inhibitor ameliorates experimental autoimmune encephalomyelitis by inhibiting T cell activation. The Journal of pharmacology and experimental therapeutics 20061101
S-adenosyl-L-homocysteine hydrolase inactivation curtails ovalbumin-induced immune responses. The Journal of pharmacology and experimental therapeutics 20060301
Properties