N6-CYCLOHEXYLADENOSINE
Title | Journal |
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Activation of adenosine₁ receptors induces antidepressant-like, anti-impulsive effects on differential reinforcement of low-rate 72-s behavior in rats. | The Journal of pharmacology and experimental therapeutics 20120501 |
Involvement of NMDA receptors in the antidepressant-like action of adenosine. | Pharmacological reports : PR 20120101 |
Adenosine A₂A and A₂B receptors are both required for adenosine A₁ receptor-mediated cardioprotection. | American journal of physiology. Heart and circulatory physiology 20110901 |
Season primes the brain in an arctic hibernator to facilitate entrance into torpor mediated by adenosine A(1) receptors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110727 |
Endogenous adenosine A1 receptor activation underlies the transient post-ischemic rhythmic delta EEG activity. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20110601 |
Adenosine reduces GABAergic IPSC frequency via presynaptic A₁ receptors in hypothalamic paraventricular neurons projecting to rostral ventrolateral medulla. | Neuroscience letters 20110218 |
Adenosine regulates Sertoli cell function by activating AMPK. | Molecular and cellular endocrinology 20101215 |
Analysis of adenosine A₂a receptor stability: effects of ligands and disulfide bonds. | Biochemistry 20101102 |
Adenosine A(1) receptor agonist N(6)-cyclohexyl-adenosine induced phosphorylation of delta opioid receptor and desensitization of its signaling. | Acta pharmacologica Sinica 20100701 |
The interaction of intrathecal neostigmine and N-cyclohexyladenosine on anti-allodynic effects in rats with a nerve ligation injury. | Korean journal of anesthesiology 20100701 |
Adenosine receptor agonists affect taurine release from mouse brain stem slices in ischemia. | Amino acids 20100501 |
Altered thermoregulation via sensitization of A1 adenosine receptors in dietary-restricted rats. | Psychopharmacology 20100401 |
Theophylline inhibits the differentiation of human monocyte into dendritic cell potentially via adenosine receptor antagonism. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091201 |
Structure-activity relationships of adenine and deazaadenine derivatives as ligands for adenine receptors, a new purinergic receptor family. | Journal of medicinal chemistry 20091008 |
Reduced expression and desensitization of adenosine A1 receptor/adenylyl cyclase pathway after chronic (-)N6-phenylisopropyladenosine intake during pregnancy. | Neuroscience 20091006 |
Activation of adenosine(1) (A(1)) receptors suppresses head shakes induced by a serotonergic hallucinogen in rats. | Neuropharmacology 20090601 |
Contribution of NO, ATP-sensitive K+ channels and prostaglandins to adenosine receptor agonists-induced relaxation of the rat tail artery. | Pharmacological reports : PR 20090101 |
Modulation of insulin release by adenosine A1 receptor agonists and antagonists in INS-1 cells: the possible contribution of 86Rb+ efflux and 45Ca2+ uptake. | Cell biochemistry and function 20081201 |
Central A1-receptor activation associated with onset of torpor protects the heart against low temperature in the Syrian hamster. | American journal of physiology. Regulatory, integrative and comparative physiology 20080901 |
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N6-substituted 3'-C-methyladenosine derivatives. | Journal of medicinal chemistry 20080724 |
Adenosine A1 receptor activation mediates NMDA receptor activity in a pertussis toxin-sensitive manner during normoxia but not anoxia in turtle cortical neurons. | Brain research 20080605 |
Role of glucose metabolism in the recovery of postischemic LV mechanical function: effects of insulin and other metabolic modulators. | American journal of physiology. Heart and circulatory physiology 20080601 |
Involvement of the adenosine A1 and A2A receptors in the antidepressant-like effect of zinc in the forced swimming test. | Progress in neuro-psychopharmacology & biological psychiatry 20080515 |
The role of piriform cortex adenosine A1 receptors on hippocampal kindling. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20080501 |
Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists. | Journal of medicinal chemistry 20080410 |
Adenosine receptor ligands protect against a combination of apoptotic and necrotic cell death in cerebellar granule neurons. | Experimental brain research 20080301 |
Alcohol related changes in regulation of NMDA receptor functions. | Current neuropharmacology 20080301 |
C-Jun N-terminal kinase regulates adenosine A1 receptor-mediated synaptic depression in the rat hippocampus. | Neuropharmacology 20071201 |
Up-regulation of adenosine A1 receptors in frontal cortex from Pick's disease cases. | The European journal of neuroscience 20071201 |
Intracellular signalling pathways in the vasoconstrictor response of mouse afferent arterioles to adenosine. | Acta physiologica (Oxford, England) 20071001 |
The role of adenosine A1 and A2A receptors of entorhinal cortex on piriform cortex kindled seizures in rats. | Pharmacological research 20070801 |
Adenosine stimulates the basolateral 50 pS K channels in the thick ascending limb of the rat kidney. | American journal of physiology. Renal physiology 20070701 |
Changes in neuromodulatory effect of adenosine A1 receptors on piriform cortex field potentials in amygdala kindled rats. | European journal of pharmacology 20070622 |
Anticonvulsant effect of A1 but not A2A adenosine receptors of piriform cortex in amygdala-kindled rats. | Canadian journal of physiology and pharmacology 20070601 |
Adenosine and sleep deprivation promote NF-kappaB nuclear translocation in cholinergic basal forebrain. | Journal of neurochemistry 20070301 |
Tonic adenosine A1 and A2A receptor activation is required for the excitatory action of VIP on synaptic transmission in the CA1 area of the hippocampus. | Neuropharmacology 20070201 |
Mechanisms linking adenosine A1 receptors and extracellular signal-regulated kinase 1/2 activation in human trabecular meshwork cells. | The Journal of pharmacology and experimental therapeutics 20070101 |
Contractile effects of adenosine, coronary flow and perfusion pressure in murine myocardium. | Pflugers Archiv : European journal of physiology 20070101 |
Modulation of ischaemic contracture in mouse hearts: a 'supraphysiological' response to adenosine. | Experimental physiology 20070101 |
Adenosine arrests apoptosis in lymphocytes but not in phagocytes from primary leucocyte cultures of the teleost fish, Sparus aurata L. | Developmental and comparative immunology 20070101 |
Co-modulation of acute ethanol-induced motor impairment by mouse cerebellar adenosinergic A1 and GABA(A) receptor systems. | Brain research bulletin 20061211 |
Transcriptional activation of c-Fos by constitutively active Galpha(16)QL through a STAT1-dependent pathway. | Cellular signalling 20061201 |
Anticonvulsant effects of N6-cyclohexyladenosine microinjected into the CA1 region of the hippocampus on entorhinal cortex-kindled seizures in rats. | Epileptic disorders : international epilepsy journal with videotape 20061201 |
The impact of adenosine and A(2B) receptors on glucose homoeostasis. | The Journal of pharmacy and pharmacology 20061201 |
Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase. | Journal of the American Society of Nephrology : JASN 20060901 |
A(1) adenosine receptor signal and AMPK involving caspase-9/-3 activation are responsible for adenosine-induced RCR-1 astrocytoma cell death. | Neurotoxicology 20060701 |
N6-Cyclohexyl-adenosine but not adenosine is a modulator of teleost fish innate immune activities. | Developmental and comparative immunology 20060101 |
Adenosine A1 and A2A receptors of hippocampal CA1 region have opposite effects on piriform cortex kindled seizures in rats. | Seizure 20060101 |
Amygdala adenosine A1 receptors have no anticonvulsant effect on piriform cortex-kindled seizures in rat. | Canadian journal of physiology and pharmacology 20060101 |
Effects of urea pretreatment on the binding properties of adenosine A1 receptors. | British journal of pharmacology 20051201 |
Adenosine A1 receptors mediate inhibition of cAMP formation in vitro in the pontine, REM sleep induction zone. | Brain research 20051109 |
Modulation of conventional outflow facility by the adenosine A1 agonist N6-cyclohexyladenosine. | Investigative ophthalmology & visual science 20051001 |
The role of adenosine A(1) receptors in the interaction between amygdala and entorhinal cortex of kindled rats. | Epilepsy research 20050601 |
Characterization of N(6)-cyclohexyladenosine-induced hypothermia in Syrian hamsters. | Journal of pharmacological sciences 20050301 |
A2A adenosine receptor induction inhibits IFN-gamma production in murine CD4+ T cells. | Journal of immunology (Baltimore, Md. : 1950) 20050115 |
Adenosine postsynaptically modulates supraoptic neuronal excitability. | Journal of neurophysiology 20050101 |
Chronic caffeine or theophylline intake during pregnancy inhibits A1 receptor function in the rat brain. | Neuroscience 20050101 |
G16-mediated activation of nuclear factor kappaB by the adenosine A1 receptor involves c-Src, protein kinase C, and ERK signaling. | The Journal of biological chemistry 20041217 |
Dietary K intake regulates the response of apical K channels to adenosine in the thick ascending limb. | American journal of physiology. Renal physiology 20041101 |
Multiple actions of extracellular ATP and adenosine on calcium currents mediated by various purinoceptors in neurons of nucleus tractus solitarius. | Neuroscience research 20041101 |
Clearance of cyclopentyladenosine and cyclohexyladenosine in rats following a single subcutaneous dose. | Pharmacological research 20040901 |
Role of adenosine A2A receptor in the regulation of gastric somatostatin release. | The Journal of pharmacology and experimental therapeutics 20040501 |
1,2,4-Triazolo[1,5-a]quinoxaline derivatives: synthesis and biological evaluation as adenosine receptor antagonists. | Farmaco (Societa chimica italiana : 1989) 20040201 |
Synthesis and structure-activity relationships of 4-cycloalkylamino-1, 2, 4-triazolo[4, 3-a]quinoxalin-1- one derivatives as A1 and A3 adenosine receptor antagonists. | Archiv der Pharmazie 20040101 |
A(2A) adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosis. | Biochemical pharmacology 20031115 |
Blood-brain barrier transport of synthetic adenosine A1 receptor agonists in vitro: structure transport relationships. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20031101 |
Regulation of peripheral inflammation by spinal adenosine: role of somatic afferent fibers. | Experimental neurology 20031101 |
Adenosine induces vasoconstriction through Gi-dependent activation of phospholipase C in isolated perfused afferent arterioles of mice. | Journal of the American Society of Nephrology : JASN 20031001 |
Interactive role of adenosine and dopamine in the opiate withdrawal syndrome. | Naunyn-Schmiedeberg's archives of pharmacology 20030801 |
Alteration of the purinergic modulation of enteric neurotransmission in the mouse ileum during chronic intestinal inflammation. | British journal of pharmacology 20030501 |
Spinal adenosine agonist reduces c-fos and astrocyte activation in dorsal horn of rats with adjuvant-induced arthritis. | Neuroscience letters 20030410 |
Opposing facilitatory and inhibitory modulation of glutamate release elicited by cAMP production in cerebrocortical nerve terminals (synaptosomes). | Neuropharmacology 20030401 |
Adenosine A1 receptors regulate the response of the mouse circadian clock to light. | Brain research 20030117 |
Characterization of N-methyl-D-aspartate-evoked taurine release in the developing and adult mouse hippocampus. | Amino acids 20030101 |
[Protective effect of A-agonists in a minimum invasive model of spinal cord ischemia in rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20030101 |
Adenosine suppresses the response of neurons to gaba in the superficial laminae of the rat spinal dorsal horn. | Neuroscience 20030101 |
Adenosinergic inhibition of basal forebrain wakefulness-active neurons: a simultaneous unit recording and microdialysis study in freely behaving cats. | Neuroscience 20030101 |
Basolateral and apical A1 adenosine receptors mediate sodium transport in cultured renal epithelial (A6) cells. | American journal of physiology. Renal physiology 20021201 |
Spinal adenosine receptor activation inhibits inflammation and joint destruction in rat adjuvant-induced arthritis. | Arthritis and rheumatism 20021101 |
Lack of central effects of peripherally administered adenosine A(1) agonists on synaptic transmission in the rat hippocampus. | Brain research 20020927 |
Presynaptic adenosine A1 receptors regulate retinohypothalamic neurotransmission in the hamster suprachiasmatic nucleus. | Journal of neurobiology 20020905 |
Adenosine induces inositol 1,4,5-trisphosphate receptor-mediated mobilization of intracellular calcium stores in basal forebrain cholinergic neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901 |
Adenosine A1 receptor modulation of MMP-2 secretion by trabecular meshwork cells. | Investigative ophthalmology & visual science 20020901 |
The effects of adenosine receptor agonists and antagonists on morphine state-dependent memory of passive avoidance. | Neurobiology of learning and memory 20020901 |
Adenosine-mediated activation of Akt/protein kinase B in the rat hippocampus in vitro and in vivo. | Neuroscience letters 20020809 |
Temperature dependence of the affinity enhancement of selective adenosine A1 receptor agonism: a thermodynamic analysis. | European journal of pharmacology 20020719 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
AT(1) and AT(2) receptor expression and blockade after acute ischemia-reperfusion in isolated working rat hearts. | American journal of physiology. Heart and circulatory physiology 20020401 |
Effects of temperature on adenosine A1 receptor activation in guinea pig hippocampus in vitro. | Pflugers Archiv : European journal of physiology 20020301 |
Interaction of angiotensin II and III with adenosine A(1) receptor-related drugs in passive avoidance conditioning in rats. | Behavioural brain research 20020201 |
Functional characterization of an endogenous Xenopus oocyte adenosine receptor. | British journal of pharmacology 20020101 |
Effects of adenosine receptor agonists and antagonists on pentylenetetrazole-induced amnesia. | European journal of pharmacology 20011102 |
Anticonvulsant effect of bilateral injection of N6-cyclohexyladenosine into the CA1 region of the hippocampus in amygdala-kindled rats. | Epilepsy research 20011101 |
Adenosine and caffeine modulate circadian rhythms in the Syrian hamster. | Neuroreport 20010917 |
Effects of angiotensin III and angiotensin IV on pentylenetetrazol seizure susceptibility (threshold and kindling): interaction with adenosine A(1) receptors. | Brain research bulletin 20010915 |
Intraocular pressure responses to the adenosine agonist cyclohexyladenosine: evidence for a dual mechanism of action. | Investigative ophthalmology & visual science 20010701 |
Modulation of ethanol-induced motor incoordination by mouse striatal A(1) adenosinergic receptor. | Brain research bulletin 20010701 |
Involvement of the cerebellar adenosine A(1) receptor in cannabinoid-induced motor incoordination in the acute and tolerant state in mice. | Brain research 20010629 |
Adenosine A1 receptors regulate the response of the hamster circadian clock to light. | European journal of pharmacology 20010223 |
Adenosine enhances glial glutamate efflux via A2a adenosine receptors. | Life sciences 20010209 |
K(ATP) channel blockers selectively interact with A(1)-adenosine receptor mediated modulation of acetylcholine release in the rat hippocampus. | Brain research 20010119 |
Adenosine activates aromatic L-amino acid decarboxylase activity in the kidney and increases dopamine. | Journal of the American Society of Nephrology : JASN 20010101 |
N6-cyclohexyladenosine and 3-(2-carboxypiperazine-4-yl)-1-propenyl-1-phosphonic acid enhance the effect of antiepileptic drugs against induced seizures in mice. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20010101 |
[Comparative characteristics of A1-receptor agonists as neuroprotective agents]. | Eksperimental'naia i klinicheskaia farmakologiia 20010101 |
Modification of cardiovascular responses to adenosine A1 receptor stimulation in the posterior hypothalamus of anaesthetized rats by cAMP and by GABA(B) receptor blockade. | Journal of autonomic pharmacology 20010101 |
Repeated adenosine pre-treatment potentiates the acute effect of methamphetamine in rats. | Japanese journal of pharmacology 20000901 |
Cerebellar CB(1) receptor mediation of Delta(9)-THC-induced motor incoordination and its potentiation by ethanol and modulation by the cerebellar adenosinergic A(1) receptor in the mouse. | Brain research 20000512 |
N-cycloalkyl derivatives of adenosine and 1-deazaadenosine as agonists and partial agonists of the A(1) adenosine receptor. | Journal of medicinal chemistry 20000127 |
Mechanisms of inhibitory effects of zinc and cadmium ions on agonist binding to adenosine A1 receptors in rat brain. | Biochemical pharmacology 19990815 |
Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors. | Biochemical pharmacology 19990101 |
K(ATP)-channel activation: effects on myocardial recovery from ischaemia and role in the cardioprotective response to adenosine A1-receptor stimulation. | British journal of pharmacology 19980601 |
2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies. | Journal of medicinal chemistry 19980507 |
Effect of adenosine receptor agonists and antagonists on morphine-induced catalepsy in mice. | European journal of pharmacology 19971029 |
Therapeutic doses of theophylline exert proconvulsant effects in developing mice. | Brain & development 19970901 |
Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261. | British journal of pharmacology 19970501 |
Inhibition of TNF-alpha expression by adenosine: role of A3 adenosine receptors. | Journal of immunology (Baltimore, Md. : 1950) 19960501 |
Selective adenosine A2A receptor/dopamine D2 receptor interactions in animal models of schizophrenia. | European journal of pharmacology 19960111 |
Effects of adenosine analogues on apomorphine-induced penile erection in rats. | General pharmacology 19951201 |
Intrastriatal Ro15-4513 functionally antagonizes ethanol-induced motor incoordination and striatal adenosinergic modulation of ethanol-induced motor incoordination in rats. | The Journal of pharmacology and experimental therapeutics 19941001 |
A binding site model and structure-activity relationships for the rat A3 adenosine receptor. | Molecular pharmacology 19940601 |
Adenosine receptors are not involved in theophylline-induced seizures. | Journal of toxicology. Clinical toxicology 19940101 |
Structure-activity relationships for 2-substituted adenosines at A1 and A2 adenosine receptors. | Pharmacology 19930101 |
Allosteric enhancement of adenosine A1 receptor binding and function by 2-amino-3-benzoylthiophenes. | Molecular pharmacology 19901201 |
Binding of the adenosine A2 receptor ligand [3H]CGS 21680 to human and rat brain: evidence for multiple affinity sites. | Journal of neurochemistry 19901101 |
Adenosine receptor antagonism accounts for the seizure-prolonging effects of aminophylline. | Pharmacology, biochemistry, and behavior 19900801 |
Caffeine-induced seizures: apparent proconvulsant action of N-ethyl carboxamidoadenosine (NECA). | Life sciences 19900101 |
Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC). | Life sciences 19890101 |
Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors. | Archives internationales de pharmacodynamie et de therapie 19880101 |
Involvement of adenosine receptor activities in aggressive responses produced by clonidine in mice. | Psychopharmacology 19840101 |
Adenosine receptor activation in human fibroblasts: nucleoside agonists and antagonists. | Canadian journal of physiology and pharmacology 19800601 |