24-Hydroxycholesterol
Title | Journal |
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Loading into nanoparticles improves quercetin's efficacy in preventing neuroinflammation induced by oxysterols. | PloS one 20140101 |
Steady-state levels of retinal 24S-hydroxycholesterol are maintained by glial cells intervention after elevation of intraocular pressure in the rat. | Acta ophthalmologica 20121101 |
Single nucleotide polymorphism in the cholesterol-24S-hydroxylase (CYP46A1) gene and its association with CFH and LOC387715 gene polymorphisms in age-related macular degeneration. | Investigative ophthalmology & visual science 20121009 |
Cholesterol metabolism is associated with soluble amyloid precursor protein production in Alzheimer's disease. | Journal of neurochemistry 20121001 |
Protective effects of 27- and 24-hydroxycholesterol against staurosporine-induced cell death in undifferentiated neuroblastoma SH-SY5Y cells. | Neuroscience letters 20120906 |
Cholesterol loss during glutamate-mediated excitotoxicity. | The EMBO journal 20120404 |
Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease. | Cell death and differentiation 20120301 |
Interactions of amyloid β peptide 1-40 and cerebrosterol. | Neurochemical research 20120301 |
Marked change in the balance between CYP27A1 and CYP46A1 mediated elimination of cholesterol during differentiation of human neuronal cells. | Neurochemistry international 20120101 |
Nuclear receptors in nonalcoholic Fatty liver disease. | Journal of lipids 20120101 |
side-chain-oxidized oxysterols upregulate ACE2 and Mas receptor in rat primary neurons. | Neuro-degenerative diseases 20120101 |
Markers of cholesterol metabolism in the brain show stronger associations with cerebrovascular disease than Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20120101 |
Changes in cholesterol metabolism-related gene expression in peripheral blood mononuclear cells from Alzheimer patients. | Lipids in health and disease 20120101 |
Beta-amyloid peptides enhance the proliferative response of activated CD4CD28 lymphocytes from Alzheimer disease patients and from healthy elderly. | PloS one 20120101 |
Brain pericytes ABCA1 expression mediates cholesterol efflux but not cellular amyloid-β peptide accumulation. | Journal of Alzheimer's disease : JAD 20120101 |
Spatial distribution of the pathways of cholesterol homeostasis in human retina. | PloS one 20120101 |
ABC Transporters and the Alzheimer's Disease Enigma. | Frontiers in psychiatry 20120101 |
Enhanced production of 24S-hydroxycholesterol is not sufficient to drive liver X receptor target genes in vivo. | Journal of internal medicine 20111001 |
24S-hydroxycholesterol and cholesterol-24S-hydroxylase (CYP46A1) in the retina: from cholesterol homeostasis to pathophysiology of glaucoma. | Chemistry and physics of lipids 20110901 |
Oxidative damage in ischemic stroke revealed using multiple biomarkers. | Stroke 20110801 |
Side chain-oxidized oxysterols regulate the brain renin-angiotensin system through a liver X receptor-dependent mechanism. | The Journal of biological chemistry 20110722 |
24(S)-hydroxycholesterol induces neuronal cell death through necroptosis, a form of programmed necrosis. | The Journal of biological chemistry 20110715 |
Biomarkers of oxidative damage in cigarette smokers: which biomarkers might reflect acute versus chronic oxidative stress? | Free radical biology & medicine 20110615 |
Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime. | Aging cell 20110601 |
Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice. | Plant foods for human nutrition (Dordrecht, Netherlands) 20110601 |
Chronic mild cerebrovascular dysfunction as a cause for Alzheimer's disease? | Experimental gerontology 20110401 |
Quantification of cholesterol-metabolizing P450s CYP27A1 and CYP46A1 in neural tissues reveals a lack of enzyme-product correlations in human retina but not human brain. | Journal of proteome research 20110107 |
Cholestenoic Acid is an important elimination product of cholesterol in the retina: comparison of retinal cholesterol metabolism with that in the brain. | Investigative ophthalmology & visual science 20110101 |
Complex genetic mechanisms in glaucoma: an overview. | Indian journal of ophthalmology 20110101 |
Role of cholesterol 24S-hydroxylase gene polymorphism (rs754203) in primary open angle glaucoma. | Molecular vision 20110101 |
Lipid pathway alterations in Parkinson's disease primary visual cortex. | PloS one 20110101 |
Mechanisms of oxysterol-induced carcinogenesis. | Lipids in health and disease 20110101 |
Oxysterol derivatives of cholesterol in neurodegenerative disorders. | Current medicinal chemistry 20110101 |
Function and comorbidities of apolipoprotein e in Alzheimer's disease. | International journal of Alzheimer's disease 20110101 |
Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments. | Journal of ophthalmology 20110101 |
Exercise-induced cognitive plasticity, implications for mild cognitive impairment and Alzheimer's disease. | Frontiers in neurology 20110101 |
Processing of endogenous AβPP in blood-brain barrier endothelial cells is modulated by liver-X receptor agonists and altered cellular cholesterol homeostasis. | Journal of Alzheimer's disease : JAD 20110101 |
Lipids, lipoproteins, and age-related macular degeneration. | Journal of lipids 20110101 |
ApoB100/LDLR-/- hypercholesterolaemic mice as a model for mild cognitive impairment and neuronal damage. | PloS one 20110101 |
Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina. | BMC ophthalmology 20110101 |
Advanced glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1. | Lipids in health and disease 20110101 |
Plasma 24S-hydroxycholesterol levels in elderly subjects with late onset Alzheimer's disease or vascular dementia: a case-control study. | BMC neurology 20110101 |
Silencing GADD153/CHOP gene expression protects against Alzheimer's disease-like pathology induced by 27-hydroxycholesterol in rabbit hippocampus. | PloS one 20110101 |
Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury. | PloS one 20110101 |
The Fox and the Rabbits-Environmental Variables and Population Genetics (1) Replication Problems in Association Studies and the Untapped Power of GWAS (2) Vitamin A Deficiency, Herpes Simplex Reactivation and Other Causes of Alzheimer's Disease. | ISRN neurology 20110101 |
Hypercholesterolemia in rats impairs the cholinergic system and leads to memory deficits. | Molecular and cellular neurosciences 20101201 |
LXR-α genomics programmes neuronal death observed in Alzheimer's disease. | Apoptosis : an international journal on programmed cell death 20101201 |
Antiproliferative effect of LXR agonists T0901317 and 22(R)-hydroxycholesterol on multiple human cancer cell lines. | Anticancer research 20100901 |
The effect of APOE genotype on brain levels of oxysterols in young and old human APOE epsilon2, epsilon3 and epsilon4 knock-in mice. | Neuroscience 20100811 |
A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol). | Biochimica et biophysica acta 20100801 |
Changes in brain cholesterol metabolome after excitotoxicity. | Molecular neurobiology 20100601 |
Distribution of cholesterol 24-hydroxylase in the monkey brain. | Neuroscience bulletin 20100601 |
Neuronal cholesterol esterification by ACAT1 in Alzheimer's disease. | IUBMB life 20100401 |
24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injury. | Brain research 20100310 |
Vascular pathology in the aged human brain. | Acta neuropathologica 20100301 |
The antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivo. | Journal of lipid research 20100201 |
Adeno-associated virus gene therapy with cholesterol 24-hydroxylase reduces the amyloid pathology before or after the onset of amyloid plaques in mouse models of Alzheimer's disease. | Molecular therapy : the journal of the American Society of Gene Therapy 20100101 |
Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids. | Biochimica et biophysica acta 20100101 |
Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs. | PloS one 20100101 |
Cardiovascular dementia - a different perspective. | The open biochemistry journal 20100101 |
Effects of simvastatin on cholesterol metabolism and Alzheimer disease biomarkers. | Alzheimer disease and associated disorders 20100101 |
Effects of cholesterol and its 24S-OH and 25-OH oxysterols on choline acetyltransferase-positive neurons in brain slices. | Pharmacology 20100101 |
The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells. | BMC ophthalmology 20100101 |
Prevention of Alzheimer's disease in high risk groups: statin therapy in subjects with PSEN1 mutations or heterozygosity for apolipoprotein E epsilon 4. | Alzheimer's research & therapy 20100101 |
Primary open-angle glaucoma: association with cholesterol 24S-hydroxylase (CYP46A1) gene polymorphism and plasma 24-hydroxycholesterol levels. | Investigative ophthalmology & visual science 20091201 |
Polar metabolite of cholesterol induces rat cognitive dysfunctions. | Neuroscience 20091201 |
Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease. | Neuroscience letters 20091002 |
24-hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver x receptor activation. | Drug metabolism and disposition: the biological fate of chemicals 20091001 |
Serum 24S-hydroxycholesterol and hippocampal size in middle-aged normal individuals. | Neurobiology of aging 20090601 |
Steroid and protein ligand binding to cytochrome P450 46A1 as assessed by hydrogen-deuterium exchange and mass spectrometry. | Biochemistry 20090519 |
Central nervous system: cholesterol turnover, brain development and neurodegeneration. | Biological chemistry 20090401 |
CYP46A1 variants influence Alzheimer's disease risk and brain cholesterol metabolism. | European psychiatry : the journal of the Association of European Psychiatrists 20090401 |
Combined use of mass spectrometry and heterologous expression for identification of membrane-interacting peptides in cytochrome P450 46A1 and NADPH-cytochrome P450 oxidoreductase. | Archives of biochemistry and biophysics 20090301 |
Sterols in the central nervous system. | Current opinion in clinical nutrition and metabolic care 20090301 |
Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS. | Journal of lipid research 20090201 |
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on beta-amyloid precursor protein levels and processing in human neuroblastoma SH-SY5Y cells. | Molecular neurodegeneration 20090101 |
Oxysterols as markers of neurological disease--a review. | Scandinavian journal of clinical and laboratory investigation 20090101 |
Long-term statin therapy and CSF cholesterol levels: implications for Alzheimer's disease. | Dementia and geriatric cognitive disorders 20090101 |
Cross-talk between oxysterols and glucocorticoids: differential regulation of secreted phopholipase A2 and impact on oligodendrocyte death. | PloS one 20090101 |
Differential effects of 24-hydroxycholesterol and 27-hydroxycholesterol on tyrosine hydroxylase and alpha-synuclein in human neuroblastoma SH-SY5Y cells. | Journal of neurochemistry 20081201 |
A comparison of the potential unfavorable effects of oxycholesterol and oxyphytosterol in mice: different effects, on cerebral 24S-hydroxychoelsterol and serum triacylglycerols levels. | Bioscience, biotechnology, and biochemistry 20081201 |
Plasma 24S-hydroxycholesterol and caudate MRI in pre-manifest and early Huntington's disease. | Brain : a journal of neurology 20081101 |
Liquid chromatography-tandem mass spectrometry determination of plasma 24S-hydroxycholesterol with chromatographic separation of 25-hydroxycholesterol. | Analytical biochemistry 20081001 |
Cortical injury increases cholesterol 24S hydroxylase (Cyp46) levels in the rat brain. | Journal of neurotrauma 20080901 |
Transcriptional regulation of the human CYP46A1 brain-specific expression by Sp transcription factors. | Journal of neurochemistry 20080701 |
Plasma 24S-hydroxycholesterol and other oxysterols in acute closed head injury. | Brain injury 20080701 |
Measurement of F2-isoprostanes, hydroxyeicosatetraenoic products, and oxysterols from a single plasma sample. | Free radical biology & medicine 20080401 |
The effect of 24S-hydroxycholesterol on cholesterol homeostasis in neurons: quantitative changes to the cortical neuron proteome. | Journal of proteome research 20080401 |
Complex of amyloid beta peptides with 24-hydroxycholesterol and its effect on hemicholinium-3 sensitive carriers. | Neurochemical research 20080301 |
[Synthesis of sterols oxygenated in the terminal fragment of their side chains]. | Bioorganicheskaia khimiia 20080101 |
Peroxisome Proliferator-Activated Receptor beta/delta in the Brain: Facts and Hypothesis. | PPAR research 20080101 |
Liver x receptor: a novel therapeutic target. | Indian journal of pharmaceutical sciences 20080101 |
Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20071226 |
Primary human astrocytes produce 24(S),25-epoxycholesterol with implications for brain cholesterol homeostasis. | Journal of neurochemistry 20071201 |
Brain-to-blood elimination of 24S-hydroxycholesterol from rat brain is mediated by organic anion transporting polypeptide 2 (oatp2) at the blood-brain barrier. | Journal of neurochemistry 20071101 |
Degradation of 24S-hydroxycholesterol in men is not regulated by CYP7A1. | International journal of clinical pharmacology and therapeutics 20071101 |
Levels of ApoE in cerebrospinal fluid are correlated with Tau and 24S-hydroxycholesterol in patients with cognitive disorders. | Neuroscience letters 20070925 |
Cholesterol biosynthesis pathway is disturbed in YAC128 mice and is modulated by huntingtin mutation. | Human molecular genetics 20070915 |
Lipoprotein distribution and biological variation of 24S- and 27-hydroxycholesterol in healthy volunteers. | Atherosclerosis 20070901 |
Plasma 24S hydroxycholesterol response to statins in Alzheimer's disease patients: effects of gender, CYP46, and ApoE polymorphisms. | Journal of molecular neuroscience : MN 20070901 |
Regulation of alpha- and beta-secretase activity by oxysterols: cerebrosterol stimulates processing of APP via the alpha-secretase pathway. | Biochemical and biophysical research communications 20070720 |
Cholesterol oxidation is increased and PUFA decreased by frozen storage and grilling of Atlantic hake fillets (Merluccius hubbsi). | Lipids 20070701 |
24S-hydroxycholesterol in relation to disease manifestations of acute experimental autoimmune encephalomyelitis. | Journal of neuroscience research 20070515 |
Unique patient with cerebrotendinous xanthomatosis. Evidence for presence of a defect in a gene that is not identical to sterol 27-hydroxylase. | Journal of internal medicine 20070501 |
Liquid chromatography-mass spectrometry utilizing multi-stage fragmentation for the identification of oxysterols. | Journal of lipid research 20070401 |
Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells. | Current eye research 20070301 |
Role of ABCG1 and ABCA1 in regulation of neuronal cholesterol efflux to apolipoprotein E discs and suppression of amyloid-beta peptide generation. | The Journal of biological chemistry 20070202 |
24S-hydroxycholesterol induces cholesterol release from choroid plexus epithelial cells in an apical- and apoE isoform-dependent manner concomitantly with the induction of ABCA1 and ABCG1 expression. | Journal of neurochemistry 20070201 |
Rediscovery of cerebrosterol. | Lipids 20070201 |
Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice. | Cell metabolism 20070101 |
[A new synthesis of cerebrosterol and its 24-epimer from lithocholic acid]. | Bioorganicheskaia khimiia 20070101 |
Extraction and analysis of sterols in biological matrices by high performance liquid chromatography electrospray ionization mass spectrometry. | Methods in enzymology 20070101 |
Crossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain. | Journal of internal medicine 20061201 |
Plasma cerebrosterol and magnetic resonance imaging measures in multiple sclerosis. | Clinical neurology and neurosurgery 20060701 |
High-dose statin treatment does not alter plasma marker for brain cholesterol metabolism in patients with moderately elevated plasma cholesterol levels. | Journal of clinical pharmacology 20060701 |
Lovastatin modulates increased cholesterol and oxysterol levels and has a neuroprotective effect on rat hippocampal neurons after kainate injury. | Journal of neuropathology and experimental neurology 20060701 |
24(S)-hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux. | The Journal of biological chemistry 20060505 |
Polymorphism in ABCA1 influences CSF 24S-hydroxycholesterol levels but is not a major risk factor of Alzheimer's disease. | International journal of molecular medicine 20060501 |
Cholesterol and 24S-hydroxycholesterol trafficking in Alzheimer's disease. | Expert review of neurotherapeutics 20060501 |
Are the CSF levels of 24S-hydroxycholesterol a sensitive biomarker for mild cognitive impairment? | Neuroscience letters 20060401 |
Brain cholesterol synthesis in mice is affected by high dose of simvastatin but not of pravastatin. | The Journal of pharmacology and experimental therapeutics 20060301 |
Polymorphisms of the cholesterol 24-hydroxylase (CYP46A1) gene and the risk of Alzheimer's disease in a Chinese population. | International psychogeriatrics 20060301 |
Polymorphism in neuropeptide Y influences CSF cholesterol levels but is no major risk factor of Alzheimer's disease. | Journal of neural transmission (Vienna, Austria : 1996) 20060201 |
Circulating biomarkers of cognitive decline and dementia. | Clinica chimica acta; international journal of clinical chemistry 20060201 |
Effect of pravastatin on plasma sterols and oxysterols in men. | European journal of clinical pharmacology 20060101 |
Cholesterol metabolism in the brain: importance of 24S-hydroxylation. | Acta neurologica Scandinavica. Supplementum 20060101 |
Oxysterols and Alzheimer's disease. | Acta neurologica Scandinavica. Supplementum 20060101 |
Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease. | Journal of biomedicine & biotechnology 20060101 |
Influence of peroxisome proliferator-activated receptor gamma gene polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients. | Journal of neural transmission (Vienna, Austria : 1996) 20051001 |
A cluster of cholesterol-related genes confers susceptibility for Alzheimer's disease. | The Journal of clinical psychiatry 20050701 |
24S-hydroxycholesterol induces inflammatory gene expression in primary human neural cells. | Neuroreport 20050621 |
Effect of raloxifene and hormone therapy on serum markers of brain and whole-body cholesterol metabolism in postmenopausal women. | Maturitas 20050411 |
Cholesterol homeostasis in neurons and glial cells. | Seminars in cell & developmental biology 20050401 |
Biological markers in CSF and blood for axonal degeneration in multiple sclerosis. | The Lancet. Neurology 20050101 |
Cholesterol and apolipoprotein E in Alzheimer's disease. | American journal of Alzheimer's disease and other dementias 20050101 |
Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16. | PLoS biology 20041001 |
Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients. | Neuroscience letters 20040930 |
Does brain specific 24S-hydroxycholesterol in plasma indicate the disruption of the blood-brain barrier in patients with ischemic stroke? | Neuroscience letters 20040923 |
Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease. | Neurobiology of aging 20040901 |
Differential expression of cholesterol hydroxylases in Alzheimer's disease. | The Journal of biological chemistry 20040813 |
Thematic review series: brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal. | Journal of lipid research 20040801 |
High doses of simvastatin, pravastatin, and cholesterol reduce brain cholesterol synthesis in guinea pigs. | Steroids 20040601 |
Brain cholesterol: long secret life behind a barrier. | Arteriosclerosis, thrombosis, and vascular biology 20040501 |
Determination of 24S- and 27-hydroxycholesterol in plasma by high-performance liquid chromatography-mass spectrometry. | Journal of lipid research 20040401 |
Diagnostic use of cerebral and extracerebral oxysterols. | Clinical chemistry and laboratory medicine 20040201 |
The effects of gender and CYP46 and apo E polymorphism on 24S-hydroxycholesterol levels in Alzheimer's patients treated with statins. | Current Alzheimer research 20040201 |
Changes in the levels of cerebral and extracerebral sterols in the brain of patients with Alzheimer's disease. | Journal of lipid research 20040101 |
Linking lipids, Alzheimer's and LXRs? | Nuclear receptor signaling 20040101 |
Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain. | Biochemistry 20031209 |
Combination of serum markers related to several mechanisms in Alzheimer's disease. | Neurobiology of aging 20031101 |
24S-hydroxycholesterol: a marker of brain cholesterol metabolism. | Pharmacopsychiatry 20030901 |
Decreased levels of the brain specific 24S-hydroxycholesterol and cholesterol precursors in serum of multiple sclerosis patients. | Neuroscience letters 20030828 |
On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation. | Journal of lipid research 20030801 |
Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover. | The Journal of biological chemistry 20030620 |
Side chain oxidized oxysterols in cerebrospinal fluid and the integrity of blood-brain and blood-cerebrospinal fluid barriers. | Journal of lipid research 20030401 |
Reduction in levels of 24S-hydroxycholesterol by statin treatment in patients with Alzheimer disease. | Archives of neurology 20030401 |
Oxysterol 7alpha-hydroxylase (CYP39A1) in the ciliary nonpigmented epithelium of bovine eye. | Laboratory investigation; a journal of technical methods and pathology 20030301 |
Serum cholesterol, precursors and metabolites and cognitive performance in an aging population. | Neurobiology of aging 20030101 |
Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. | Archives of neurology 20030101 |
The role of 24S-hydroxycholesterol in Alzheimer's disease. | The journal of nutrition, health & aging 20030101 |
Induction of the cholesterol transporter ABCA1 in central nervous system cells by liver X receptor agonists increases secreted Abeta levels. | The Journal of biological chemistry 20021213 |
Changes in human plasma levels of the brain specific oxysterol 24S-hydroxycholesterol during progression of multiple sclerosis. | Neuroscience letters 20021018 |
Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis. | The Journal of biological chemistry 20020913 |
Metabolism of 4 beta -hydroxycholesterol in humans. | The Journal of biological chemistry 20020830 |
Cerebrospinal fluid 24S-hydroxycholesterol is increased in patients with Alzheimer's disease compared to healthy controls. | Neuroscience letters 20020510 |
Reduction of plasma 24S-hydroxycholesterol (cerebrosterol) levels using high-dosage simvastatin in patients with hypercholesterolemia: evidence that simvastatin affects cholesterol metabolism in the human brain. | Archives of neurology 20020201 |
24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. | Journal of psychiatric research 20020101 |
Polymorphism in the cholesterol 24S-hydroxylase gene is associated with Alzheimer's disease. | Molecular psychiatry 20020101 |
On the turnover of brain cholesterol in patients with Alzheimer's disease. Abnormal induction of the cholesterol-catabolic enzyme CYP46 in glial cells. | Neuroscience letters 20011113 |
Antiepileptic drugs increase plasma levels of 4beta-hydroxycholesterol in humans: evidence for involvement of cytochrome p450 3A4. | The Journal of biological chemistry 20011019 |
From brain to bile. Evidence that conjugation and omega-hydroxylation are important for elimination of 24S-hydroxycholesterol (cerebrosterol) in humans. | The Journal of biological chemistry 20011005 |
Cholesterol dynamics in the foetal and neonatal brain as reflected by circulatory levels of 24S-hydroxycholesterol. | Acta paediatrica (Oslo, Norway : 1992) 20010601 |
Oxysterols in the circulation of patients with the Smith-Lemli-Opitz syndrome: abnormal levels of 24S- and 27-hydroxycholesterol. | Journal of lipid research 20010301 |
Evidence that the major oxysterols in human circulation originate from distinct pools of cholesterol: a stable isotope study. | Journal of lipid research 20010101 |
Neurotoxicity of 24-hydroxycholesterol, an important cholesterol elimination product of the brain, may be prevented by vitamin E and estradiol-17beta. | Journal of neural transmission (Vienna, Austria : 1996) 20010101 |
24-hydroxycholesterol is a substrate for hepatic cholesterol 7alpha-hydroxylase (CYP7A). | Journal of lipid research 20001001 |
Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol. | The Journal of biological chemistry 20000602 |
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway. | The Journal of biological chemistry 19970207 |
24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver. | Biochimica et biophysica acta 19930224 |