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butizide

CAS No.:
2043-38-1
Catalog Number:
AG00C2KN
Molecular Formula:
Molecular Weight:
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Product Description
Catalog Number:
AG00C2KN
Chemical Name:
butizide
CAS Number:
2043-38-1
MDL Number:
MFCD00867351
IUPAC Name:
6-chloro-3-(2-methylpropyl)-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide
InChI:
InChI=1S/C11H16ClN3O4S2/c1-6(2)3-11-14-8-4-7(12)9(20(13,16)17)5-10(8)21(18,19)15-11/h4-6,11,14-15H,3H2,1-2H3,(H2,13,16,17)
InChI Key:
HGBFRHCDYZJRAO-UHFFFAOYSA-N
EC Number:
218-048-8
Properties
Complexity:
582  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
353.027g/mol
Formal Charge:
0
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
353.836g/mol
Monoisotopic Mass:
353.027g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
135A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
1.1  
Literature
Title Journal
Simultaneous identification and quantification of canrenone and 11-α-hydroxy-canrenone by LC-MS and HPLC-UVD. Journal of biomedicine & biotechnology 20110101
[Chlorthalidone better than hydrochlorothiazide in hypertension]. Nederlands tijdschrift voor geneeskunde 20100101
Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases. The Journal of clinical endocrinology and metabolism 20090901
Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure. Journal of hypertension 20090801
Amlodipine/valsartan/hydrochlorothiazide: fixed-dose combination in hypertension. American journal of cardiovascular drugs : drugs, devices, and other interventions 20090101
LC and LC-MS methods for the investigation of polypills for the treatment of cardiovascular diseases. Part 1. Separation of active components and classification of their interaction/degradation products. Journal of pharmaceutical and biomedical analysis 20080715
Screening procedure for detection of diuretics and uricosurics and/or their metabolites in human urine using gas chromatography-mass spectrometry after extractive methylation. Therapeutic drug monitoring 20050801
A case of gain-of-function mutation in calcium-sensing receptor: supplemental hydration is required for renal protection. Clinical nephrology 20050601
[Anxiodepressive and neuromediatory disorders in hypertensive patients. Effects of cypramil therapy]. Terapevticheskii arkhiv 20050101
Phototoxicity to diuretics and antidiabetics in the cultured keratinocyte cell line HaCaT: evaluation by clonogenic assay and single cell gel electrophoresis Comet assay). Photodermatology, photoimmunology & photomedicine 20020401
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics. Journal of cardiovascular pharmacology 19850101
Ex vivo antigen preparation for the serological detection of drug-dependent antibodies in immune haemolytic anaemias. British journal of haematology 19841101
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