Home Other Building Blocks ALTERNARIOL MONOMETHYL ETHER

ALTERNARIOL MONOMETHYL ETHER

CAS No.:
26894-49-5
Catalog Number:
AG00C220
Molecular Formula:
Molecular Weight:
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Product Description
Catalog Number:
AG00C220
Chemical Name:
ALTERNARIOL MONOMETHYL ETHER
CAS Number:
26894-49-5
MDL Number:
MFCD00058532
IUPAC Name:
3,7-dihydroxy-9-methoxy-1-methylbenzo[c]chromen-6-one
InChI:
InChI=1S/C15H12O5/c1-7-3-8(16)4-12-13(7)10-5-9(19-2)6-11(17)14(10)15(18)20-12/h3-6,16-17H,1-2H3
InChI Key:
LCSDQFNUYFTXMT-UHFFFAOYSA-N
UNII:
Y79STA800H
NSC Number:
638262
Properties
Complexity:
385  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
272.068g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
272.256g/mol
Monoisotopic Mass:
272.068g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
76A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.2  
Literature
Title Journal
Impact of phase I metabolism on uptake, oxidative stress and genotoxicity of the emerging mycotoxin alternariol and its monomethyl ether in esophageal cells. Archives of toxicology 20170101
Dual effectiveness of Alternaria but not Fusarium mycotoxins against human topoisomerase II and bacterial gyrase. Archives of toxicology 20170101
Impact of Alternaria toxins on CYP1A1 expression in different human tumor cells and relevance for genotoxicity. Toxicology letters 20160105
Modulation of the cellular redox status by the Alternaria toxins alternariol and alternariol monomethyl ether. Toxicology letters 20130110
Minor contribution of alternariol, alternariol monomethyl ether and tenuazonic acid to the genotoxic properties of extracts from Alternaria alternata infested rice. Toxicology letters 20121002
Heptaketides with antiviral activity from three endolichenic fungal strains Nigrospora sp., Alternaria sp. and Phialophora sp. Fitoterapia 20120901
The Alternaria mycotoxins alternariol and alternariol methyl ether induce cytochrome P450 1A1 and apoptosis in murine hepatoma cells dependent on the aryl hydrocarbon receptor. Archives of toxicology 20120401
Mouse hepatoma cell lines differing in aryl hydrocarbon receptor-mediated signaling have different activities for glucuronidation. Archives of toxicology 20120401
Identification of a polyketide synthase required for alternariol (AOH) and alternariol-9-methyl ether (AME) formation in Alternaria alternata. PloS one 20120101
Mechanism of Alternariol monomethyl ether-induced mitochondrial apoptosis in human colon carcinoma cells. Toxicology 20111218
Influence of water activity and temperature on growth and mycotoxin production by Alternaria alternata on irradiated soya beans. International journal of food microbiology 20110915
Oxidative metabolism of the mycotoxins alternariol and alternariol-9-methyl ether in precision-cut rat liver slices in vitro. Molecular nutrition & food research 20110701
AFLP variability, toxin production, and pathogenicity of Alternaria species from Argentinean tomato fruits and puree. International journal of food microbiology 20110227
[Simultaneous determination of four Alternaria toxins in apple juice concentrate by ultra performance liquid chromatography-electrospray ionization tandem mass spectrometry]. Se pu = Chinese journal of chromatography 20101201
Water activity and temperature effects on mycotoxin production by Alternaria alternata on a synthetic tomato medium. International journal of food microbiology 20100901
Impact of water activity and temperature on growth and alternariol and alternariol monomethyl ether production of Alternaria alternata isolated from soybean. Journal of food protection 20100201
Effects of gamma radiation on the growth of Alternaria alternata and on the production of alternariol and alternariol monomethyl ether in sunflower seeds. Food microbiology 20091201
Stable isotope dilution assays of alternariol and alternariol monomethyl ether in beverages. Journal of agricultural and food chemistry 20090624
The mycotoxins alternariol and alternariol methyl ether negatively affect progesterone synthesis in porcine granulosa cells in vitro. Toxicology letters 20090425
Alternariol acts as a topoisomerase poison, preferentially affecting the IIalpha isoform. Molecular nutrition & food research 20090401
Cytotoxic metabolites from the fungal endophyte Alternaria sp. and their subsequent detection in its host plant Polygonum senegalense. Journal of natural products 20080601
Alternaria toxins in wheat during the 2004 to 2005 Argentinean harvest. Journal of food protection 20080601
Mycotoxin production by Alternaria strains isolated from Argentinean wheat. International journal of food microbiology 20071101
Analysis of alternariol and alternariol monomethyl ether on flavedo and albedo tissues of tangerines (Citrus reticulata) with symptoms of alternaria brown spot. Journal of agricultural and food chemistry 20070627
Novel oxidative in vitro metabolites of the mycotoxins alternariol and alternariol methyl ether. Molecular nutrition & food research 20070301
[Putative mycotoxin-producing fungi isolated from alpataco (Prosopis flexuosa) fruits]. Revista iberoamericana de micologia 20070301
Real-time PCR quantification of the AM-toxin gene and HPLC qualification of toxigenic metabolites from Alternaria species from apples. International journal of food microbiology 20060901
Mycoflora and occurrence of alternariol and alternariol monomethyl ether in Brazilian sunflower from sowing to harvest. Journal of agricultural and food chemistry 20050713
Liquid chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry of the Alternaria mycotoxins alternariol and alternariol monomethyl ether in fruit juices and beverages. Journal of chromatography. A 20030523
Survey of Brazilian tomato products for alternariol, alternariol monomethyl ether, tenuazonic acid and cyclopiazonic acid. Food additives and contaminants 20010701
Production of alternariol and alternariol methyl ether by Alternaria alternata grown on fruits at various temperatures. Journal of food protection 20010401
Examination of Alternaria alternata mutagenicity and effects of nitrosylation using the Ames Salmonella test. Teratogenesis, carcinogenesis, and mutagenesis 20010101
Analysis of toxic effects of Alternaria toxins on esophagus of mice by light and electron microscopy. Toxicologic pathology 20010101
Analysis of agricultural commodities and foods for Alternaria mycotoxins. Journal of AOAC International 20010101
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