5-(4-Fluorophenyl)-3-(3-nitrophenyl)-1,2,4-oxadiazole
| Title | Journal |
|---|---|
| A comparison of the embryonic stem cell test and whole embryo culture assay combined with the BeWo placental passage model for predicting the embryotoxicity of azoles. | Toxicology letters 20180401 |
| A transcriptomic approach for evaluating the relative potency and mechanism of action of azoles in the rat Whole Embryo Culture. | Toxicology 20171201 |
| Mixture effects of azole fungicides on the adrenal gland in a broad dose range. | Toxicology 20170615 |
| Development of a common carp (Cyprinus carpio) pregnane X receptor (cPXR) transactivation reporter assay and its activation by azole fungicides and pharmaceutical chemicals. | Toxicology in vitro : an international journal published in association with BIBRA 20170601 |
| Embryotoxic and pharmacologic potency ranking of six azoles in the rat whole embryo culture by morphological and transcriptomic analysis. | Toxicology and applied pharmacology 20170501 |
| Ebselen alters cellular oxidative status and induces endoplasmic reticulum stress in rat hippocampal astrocytes. | Toxicology 20160516 |
| Combination effects of azole fungicides in male rats in a broad dose range. | Toxicology 20160429 |
| The seleno-organic compound ebselen impairs mitochondrial physiology and induces cell death in AR42J cells. | Toxicology letters 20140917 |
| Imidazolylchromanones containing non-benzylic oxime ethers: synthesis and molecular modeling study of new azole antifungals selective against Cryptococcus gattii. | European journal of medicinal chemistry 20140409 |
| N-substituted 2-isonicotinoylhydrazinecarboxamides--new antimycobacterial active molecules. | Molecules (Basel, Switzerland) 20140328 |
| Glutathione peroxidase mimic ebselen improves glucose-stimulated insulin secretion in murine islets. | Antioxidants & redox signaling 20140110 |
| In vitro glutathione peroxidase mimicry of ebselen is linked to its oxidation of critical thiols on key cerebral suphydryl proteins - A novel component of its GPx-mimic antioxidant mechanism emerging from its thiol-modulated toxicology and pharmacology. | Chemico-biological interactions 20131025 |
| Candida tropicalis antifungal cross-resistance is related to different azole target (Erg11p) modifications. | Antimicrobial agents and chemotherapy 20131001 |
| Isavuconazole activity against Aspergillus lentulus, Neosartorya udagawae, and Cryptococcus gattii, emerging fungal pathogens with reduced azole susceptibility. | Journal of clinical microbiology 20130901 |
| Interrogating a hexokinase-selected small-molecule library for inhibitors of Plasmodium falciparum hexokinase. | Antimicrobial agents and chemotherapy 20130801 |
| Epidemiological cutoff values for fluconazole, itraconazole, posaconazole, and voriconazole for six Candida species as determined by the colorimetric Sensititre YeastOne method. | Journal of clinical microbiology 20130801 |
| Ebselen reduces the toxicity of mechlorethamine in A-431 cells via inhibition of apoptosis. | Journal of biochemical and molecular toxicology 20130601 |
| Development of an HTS assay for EPHX2 phosphatase activity and screening of nontargeted libraries. | Analytical biochemistry 20130301 |
| Mitochondrial electron transfer chain complexes inhibition by different organochalcogens. | Toxicology in vitro : an international journal published in association with BIBRA 20130201 |
| Milbemycins: more than efflux inhibitors for fungal pathogens. | Antimicrobial agents and chemotherapy 20130201 |
| Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose. | The Journal of biological chemistry 20121102 |
| In vitro evaluation of Malassezia pachydermatis susceptibility to azole compounds using E-test and CLSI microdilution methods. | Medical mycology 20121101 |
| A defect in iron uptake enhances the susceptibility of Cryptococcus neoformans to azole antifungal drugs. | Fungal genetics and biology : FG & B 20121101 |
| 1,3-Azoles from ortho-naphthoquinones: synthesis of aryl substituted imidazoles and oxazoles and their potent activity against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry 20121101 |
| Design and synthesis of potent hydroxyethylamine (HEA) BACE-1 inhibitors carrying prime side 4,5,6,7-tetrahydrobenzazole and 4,5,6,7-tetrahydropyridinoazole templates. | Bioorganic & medicinal chemistry letters 20121101 |
| Design, synthesis and biological evaluation of heterocyclic azoles derivatives containing pyrazine moiety as potential telomerase inhibitors. | Bioorganic & medicinal chemistry 20121101 |
| Lysine deacetylases Hda1 and Rpd3 regulate Hsp90 function thereby governing fungal drug resistance. | Cell reports 20121025 |
| Iron-catalyzed N-alkylation of azoles via cleavage of an sp3 C-H bond adjacent to a nitrogen atom. | The Journal of organic chemistry 20121019 |
| Vibrational spectra of water solutions of azoles from QM/MM calculations: effects of solvation. | The journal of physical chemistry. A 20121018 |
| A hydrogen peroxide electrode assay to measure thiol peroxidase activity for organoselenium and organotellurium drugs. | Analytical biochemistry 20121015 |
| Ontogeny and sorafenib metabolism. | Clinical cancer research : an official journal of the American Association for Cancer Research 20121015 |
| Synthesis and CYP26A1 inhibitory activity of novel methyl 3-[4-(arylamino)phenyl]-3-(azole)-2,2-dimethylpropanoates. | Bioorganic & medicinal chemistry 20121015 |
| One-pot sequential direct C-H bond arylation of azoles catalyzed by [Pd(phen)2](PF6)2: synthetic methods for triarylated azoles. | The Journal of organic chemistry 20121005 |
| Systemic effects of oral budesonide in hematopoietic transplant: implications of drug interaction with azoles. | Bone marrow transplantation 20121001 |
| Theoretical study on novel nitrogen-rich energetic compounds of bis(amino)-azobis(azoles) with tetrazene unit. | Journal of molecular modeling 20121001 |
| Sublethal concentrations of azoles induce tri transcript levels and trichothecene production in Fusarium graminearum. | FEMS microbiology letters 20121001 |
| Association between incidence of candidaemia and consumption of antifungal agents at a medical centre in Taiwan. | International journal of antimicrobial agents 20121001 |
| The biology and chemistry of antifungal agents: a review. | Bioorganic & medicinal chemistry 20121001 |
| Antiarrhythmic drug amiodarone displays antifungal activity, induces irregular calcium response and intracellular acidification of Aspergillus niger - amiodarone targets calcium and pH homeostasis of A. niger. | Fungal genetics and biology : FG & B 20121001 |
| Axially coordinated chiral salen Mn(III) anchored onto azole onium modified ZnPS-PVPA as effective catalysts for asymmetric epoxidation of unfunctionalized olefins. | Dalton transactions (Cambridge, England : 2003) 20120921 |
| In vivo emergence of Aspergillus terreus with reduced azole susceptibility and a Cyp51a M217I alteration. | The Journal of infectious diseases 20120915 |
| Coupling reactions of heteroarenes with phosphites under silver catalysis. | The Journal of organic chemistry 20120907 |
| Cloning of the lanosterol 14-α-demethylase ( ERG11 ) gene in Trichosporon asahii: a possible association between G453R amino acid substitution and azole resistance in T. asahii. | FEMS yeast research 20120901 |
| Synthesis of some azoles incorporating a sulfonamide moiety as anticonvulsant agents. | Archiv der Pharmazie 20120901 |
| Relationship between respiration deficiency and azole resistance in clinical Candida glabrata. | FEMS yeast research 20120901 |
| Design of novel dihydroxynaphthoic acid inhibitors of Plasmodium falciparum lactate dehydrogenase. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20120901 |
| Validation of the multiple sensor mechanism of the Keap1-Nrf2 system. | Free radical biology & medicine 20120815 |
| Spiropyran-based hyperbranched star copolymer: synthesis, phototropy, FRET, and bioapplication. | Biomacromolecules 20120813 |
| Chemoselective N-acylation of indoles and oxazolidinones with carbonylazoles. | Angewandte Chemie (International ed. in English) 20120813 |
| Ebselen inhibits iron-induced tau phosphorylation by attenuating DMT1 up-regulation and cellular iron uptake. | Neurochemistry international 20120801 |
| An automated method for the simultaneous measurement of azole antifungal drugs in human plasma or serum using turbulent flow liquid chromatography-tandem mass spectrometry. | Analytical and bioanalytical chemistry 20120801 |
| Pharmacotherapy approaches to antifungal prophylaxis. | Expert opinion on pharmacotherapy 20120801 |
| Environment-sensitive fluorophores with benzothiadiazole and benzoselenadiazole structures as candidate components of a fluorescent polymeric thermometer. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120727 |
| Synthesis and biological evaluation of vinyl ether-containing azole derivatives as inhibitors of Trichophyton rubrum. | Bioorganic & medicinal chemistry letters 20120715 |
| New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents. | Molecules (Basel, Switzerland) 20120710 |
| Copper-mediated and copper-catalyzed cross-coupling of indoles and 1,3-azoles: double C-H activation. | Angewandte Chemie (International ed. in English) 20120709 |
| Adverse interactions between antifungal azoles and vincristine: review and analysis of cases. | Mycoses 20120701 |
| The H2O2 scavenger ebselen decreases ethanol-induced locomotor stimulation in mice. | Drug and alcohol dependence 20120701 |
| Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits. | Chemistry & biology 20120622 |
| T-type calcium channel blockade improves survival and cardiovascular function in thalassemic mice. | European journal of haematology 20120601 |
| Distribution, behavior and fate of azole antifungals during mechanical, biological, and chemical treatments in sewage treatment plants in China. | The Science of the total environment 20120601 |
| Enantiomeric determination of azole antifungals in wastewater and sludge by liquid chromatography-tandem mass spectrometry. | Analytical and bioanalytical chemistry 20120601 |
| New therapeutic options for onychomycosis. | Expert opinion on pharmacotherapy 20120601 |
| Ebselen reduces hyperglycemia temporarily-induced by diazinon: a compound with insulin-mimetic properties. | Chemico-biological interactions 20120530 |
| Species and susceptibility distribution of 1062 clinical yeast isolates to azoles, echinocandins, flucytosine and amphotericin B from a multi-centre study. | Mycoses 20120501 |
| Synthesis, structure, and biological activity of novel (oxdi/tri)azoles derivatives containing 1,2,3-thiadiazole or methyl moiety. | Molecular diversity 20120501 |
| A case series of the management of symptomatic azole-resistant candida. | International journal of STD & AIDS 20120501 |
| o-Iodoxybenzoic acid mediated oxidative desulfurization initiated domino reactions for synthesis of azoles. | The Journal of organic chemistry 20120420 |
| Direct heteroarylation of tautomerizable heterocycles into unsymmetrical and symmetrical biheterocycles via Pd/Cu-catalyzed phosphonium coupling. | Organic letters 20120406 |
| Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ. | Toxicology and applied pharmacology 20120315 |
| Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals. | Drug metabolism and disposition: the biological fate of chemicals 20120301 |
| Effect of pH on in vitro susceptibility of Candida glabrata and Candida albicans to 11 antifungal agents and implications for clinical use. | Antimicrobial agents and chemotherapy 20120301 |
| Cathepsin cleavage of sirtuin 1 in endothelial progenitor cells mediates stress-induced premature senescence. | The American journal of pathology 20120301 |
| The V-ATPase as a target for antifungal drugs. | Current protein & peptide science 20120301 |
| Synthesis, characterization and antiamoebic activity of some hydrazone and azole derivatives bearing pyridyl moiety as a promising heterocyclic scaffold. | European journal of medicinal chemistry 20120301 |
| Prediction of the lipophilicity of nine new synthesized selenazoly and three aroyl-hydrazinoselenazoles derivatives by reversed-phase high performance thin-layer chromatography. | Journal of chromatographic science 20120301 |
| Comparison of ultrasound-assisted emulsification and dispersive liquid-liquid microextraction methods for the speciation of inorganic selenium in environmental water samples using low density extraction solvents. | Analytica chimica acta 20120210 |
| Characterization of clinical strains of Aspergillus terreus complex: molecular identification and antifungal susceptibility to azoles and amphotericin B. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20120201 |
| Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induced neurotoxicity. | Toxicology and applied pharmacology 20120201 |
| New developments in invasive fungal disease. | Future microbiology 20120201 |
| Multifunctional Ebselen drug functions through the activation of DNA damage response and alterations in nuclear proteins. | Biochemical pharmacology 20120115 |
| The combination of organoselenium compounds and guanosine prevents glutamate-induced oxidative stress in different regions of rat brains. | Brain research 20120109 |
| Evaluation of fluorescent phosphatidylserine substrates for the aminophospholipid flippase in mammalian cells. | Journal of fluorescence 20120101 |
| Ebselen is a new skin depigmenting agent that inhibits melanin biosynthesis and melanosomal transfer. | Experimental dermatology 20120101 |
| Production of prostaglandins, isoprostanes and thromboxane by Aspergillus fumigatus: identification by gas chromatography-tandem mass spectrometry and quantification by enzyme immunoassay. | Molecular immunology 20120101 |
| Novel 1,3,4-heterodiazole analogues: synthesis and in-vitro antitumor activity. | European journal of medicinal chemistry 20120101 |
| Azole antimycotics--a highway to new drugs or a dead end? | Current medicinal chemistry 20120101 |
| Invasive pulmonary aspergillosis due to a multi-azole resistant Aspergillus fumigatus. | Acta clinica Belgica 20120101 |
| Comparison of human and soil Candida tropicalis isolates with reduced susceptibility to fluconazole. | PloS one 20120101 |
| The essential oil of Melaleuca alternifolia (tea tree oil) and its main component, terpinen-4-ol protect mice from experimental oral candidiasis. | Biological & pharmaceutical bulletin 20120101 |
| Role of reactive oxygen species in transforming growth factor beta1-induced alpha smooth-muscle actin and collagen production in nasal polyp-derived fibroblasts. | International archives of allergy and immunology 20120101 |
| [Azole resistance in Aspergillus fumigatus in the Netherlands--increase due to environmental fungicides?]. | Nederlands tijdschrift voor geneeskunde 20120101 |
| Functional characterization of the small heat shock protein Hsp12p from Candida albicans. | PloS one 20120101 |
| The protective effect of ebselen on radiocontrast-induced nephrotoxicity. | Renal failure 20120101 |
| Influence of iron regulation on the metabolome of Cryptococcus neoformans. | PloS one 20120101 |
| Blockade of K+ and Ca2+ channels by azole antifungal agents in neonatal rat ventricular myocytes. | Biological & pharmaceutical bulletin 20120101 |
| Neuroprotection for stroke: current status and future perspectives. | International journal of molecular sciences 20120101 |
| Efficient synthesis of biazoles by aerobic oxidative homocoupling of azoles catalyzed by a copper(I)/2-pyridonate catalytic system. | Chemical communications (Cambridge, England) 20111228 |
| A superoxide anion-scavenger, 1,3-selenazolidin-4-one suppresses serum deprivation-induced apoptosis in PC12 cells by activating MAP kinase. | Toxicology and applied pharmacology 20111215 |
| Modeling the mechanism of the glutathione peroxidase mimic ebselen. | Inorganic chemistry 20111205 |
| Synthesis and antifungal activity of 1-[(2-benzyloxy)phenyl]-2-(azol-1-yl)ethanone derivatives: exploring the scaffold flexibility. | Chemical biology & drug design 20111201 |
| Microwave-assisted Pd/Cu-catalyzed C-8 direct alkenylation of purines and related azoles: an alternative access to 6,8,9-trisubstituted purines. | The Journal of organic chemistry 20111118 |
| Synthesis, structure, and glutathione peroxidase-like activity of amino acid containing ebselen analogues and diaryl diselenides. | Chemistry (Weinheim an der Bergstrasse, Germany) 20111104 |
| Carboxyl-ebselen-based layer-by-layer films as potential antithrombotic and antimicrobial coatings. | Biomaterials 20111101 |
| 1-[(2-arylthiazol-4-yl)methyl]azoles as a new class of anticonvulsants: design, synthesis, in vivo screening, and in silico drug-like properties. | Chemical biology & drug design 20111101 |
| Synthesis and antimicrobial activity of amido linked pyrrolyl and pyrazolyl-oxazoles, thiazoles and imidazoles. | European journal of medicinal chemistry 20111101 |
| The structure-function relationship of the Aspergillus fumigatuscyp51A L98H conversion by site-directed mutagenesis: the mechanism of L98H azole resistance. | Fungal genetics and biology : FG & B 20111101 |
| Sodium butyrate inhibits pathogenic yeast growth and enhances the functions of macrophages. | The Journal of antimicrobial chemotherapy 20111101 |
| Developing Drosophila suzukii management programs for sweet cherry in the western United States. | Pest management science 20111101 |
| A facile synthesis of carbocycle-fused mono and bis-1,2,3-selenadiazoles and their antimicrobial and antimycobacterial studies. | European journal of medicinal chemistry 20111101 |
| Synthesis and anti-inflammatory activity of some new 4,5-dihydro-1,5-diaryl-1H-pyrazole-3-substituted-heteroazole derivatives. | Bioorganic & medicinal chemistry letters 20111101 |
| Palladium-catalyzed desulfitative C-H arylation of azoles with sodium sulfinates. | Organic & biomolecular chemistry 20111026 |
| Direct C2-alkylation of azoles with alcohols and ethers through dehydrogenative cross-coupling under metal-free conditions. | Organic letters 20111007 |
| [A retrospective analysis of neurotoxicity induced by vinca alkaloids combined with azole anti-fungal agents in hematological malignancies]. | Gan to kagaku ryoho. Cancer & chemotherapy 20111001 |
| Clinical implications of azole resistance in Aspergillus fumigatus, The Netherlands, 2007-2009. | Emerging infectious diseases 20111001 |
| Diphenyl diselenide and analogs are substrates of cerebral rat thioredoxin reductase: a pathway for their neuroprotective effects. | Neuroscience letters 20110926 |
| Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice. | Circulation research 20110916 |
| Modelling inorganic biocide emission from treated wood in water. | Journal of hazardous materials 20110915 |
| ADH1 expression inversely correlates with CDR1 and CDR2 in Candida albicans from chronic oral candidosis in APECED (APS-I) patients. | FEMS yeast research 20110901 |
| Reactive oxygen species formation during tetanic contractions in single isolated Xenopus myofibers. | Journal of applied physiology (Bethesda, Md. : 1985) 20110901 |
| Synthesis, characterization of some benzazoles bearing pyridine moiety: search for novel anticancer agents. | European journal of medicinal chemistry 20110901 |
| Hsp90 governs dispersion and drug resistance of fungal biofilms. | PLoS pathogens 20110901 |
| Tandem MS analysis of selenamide-derivatized peptide ions. | Journal of the American Society for Mass Spectrometry 20110901 |
| Nickel-catalyzed C-H arylation of azoles with haloarenes: scope, mechanism, and applications to the synthesis of bioactive molecules. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110829 |
| Chain-length dependence of insertion, desorption, and translocation of a homologous series of 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled aliphatic amines in membranes. | The journal of physical chemistry. B 20110825 |
| Interaction of 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled fatty amines with 1-palmitoyl, 2-oleoyl-sn-glycero-3-phosphocholine bilayers: a molecular dynamics study. | The journal of physical chemistry. B 20110825 |
| Direct amidation of azoles with formamides via metal-free C-H activation in the presence of tert-butyl perbenzoate. | Chemical communications (Cambridge, England) 20110821 |
| An MD2 hot-spot-mimicking peptide that suppresses TLR4-mediated inflammatory response in vitro and in vivo. | Chembiochem : a European journal of chemical biology 20110816 |
| Copper-catalyzed direct thiolation of azoles with aliphatic thiols. | Organic & biomolecular chemistry 20110807 |
| The influence of low oxygen on macrophage response to Leishmania infection. | Scandinavian journal of immunology 20110801 |
| Structure-based design, synthesis, and antifungal activity of new triazole derivatives. | Chemical biology & drug design 20110801 |
| Boric acid for recurrent vulvovaginal candidiasis: the clinical evidence. | Journal of women's health (2002) 20110801 |
| Novel micelle formulations to increase cutaneous bioavailability of azole antifungals. | Journal of controlled release : official journal of the Controlled Release Society 20110730 |
| Trace analysis of pesticides in paddy field water by direct injection using liquid chromatography-quadrupole-linear ion trap-mass spectrometry. | Journal of chromatography. A 20110729 |
| Mechanistic investigations on the efficient catalytic decomposition of peroxynitrite by ebselen analogues. | Organic & biomolecular chemistry 20110721 |
| Synthesis and activities of naphthalimide azoles as a new type of antibacterial and antifungal agents. | Bioorganic & medicinal chemistry letters 20110715 |
| Species distribution and antifungal susceptibility of blood Candida isolates at a tertiary hospital in southern Taiwan, 1999-2006. | Mycoses 20110701 |
| Reactive oxygen species (ROS) from NADPH and xanthine oxidase modulate the cutaneous local heating response in healthy humans. | Journal of applied physiology (Bethesda, Md. : 1985) 20110701 |
| In vivo and in vitro characterization of a first-in-class novel azole analog that targets pregnane X receptor activation. | Molecular pharmacology 20110701 |
| Candida bloodstream infections: comparison of species distribution and resistance to echinocandin and azole antifungal agents in Intensive Care Unit (ICU) and non-ICU settings in the SENTRY Antimicrobial Surveillance Program (2008-2009). | International journal of antimicrobial agents 20110701 |
| Outcome analysis of invasive aspergillosis in hematologic malignancy and hematopoietic stem cell transplant patients: the role of novel antimold azoles. | The oncologist 20110701 |
| Structural characterization of individual vesicles using fluorescence microscopy. | Analytical chemistry 20110615 |
| Methylmercury-induced alterations in astrocyte functions are attenuated by ebselen. | Neurotoxicology 20110601 |
| Determination of azoles in sewage sludge from Spanish wastewater treatment plants by liquid chromatography-tandem mass spectrometry. | Journal of separation science 20110601 |
| Interaction of 1,2,5-chalcogenadiazole derivatives with thiophenolate: hypercoordination with formation of interchalcogen bond versus reduction to radical anion. | The journal of physical chemistry. A 20110512 |
| Preventing metal-mediated oxidative DNA damage with selenium compounds. | Metallomics : integrated biometal science 20110501 |
| Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans. | Archives of biochemistry and biophysics 20110501 |
| Acute hypoxia stimulates intracellular peroxynitrite formation associated with pulmonary artery smooth muscle cell proliferation. | Journal of cardiovascular pharmacology 20110501 |
| The reaction of azoles with 17-chloro-16-formylandrosta-5,16-dien-3β-yl-acetate: synthesis and structural elucidation of novel 16-azolylmethylene-17-oxoandrostanes. | Steroids 20110501 |
| Synthesis and evaluation of new furanyl and thiophenyl azoles as antileishmanial agents. | European journal of medicinal chemistry 20110501 |
| Candida urinary tract infections--treatment. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110501 |
| Labeling membranes with fluorescent cholesterols. | Cold Spring Harbor protocols 20110501 |
| [Fungal infections in children with malignant disease]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20110501 |
| Drug-drug interactions by azole antifungals: Beyond a dogma of CYP3A4 enzyme activity inhibition. | Toxicology letters 20110425 |
| Synthesis and antioxidant activity of peptide-based ebselen analogues. | Chemistry (Weinheim an der Bergstrasse, Germany) 20110418 |
| Design and synthesis of Selenazole-containing peptides for cocrystallization with P-glycoprotein. | Chembiochem : a European journal of chemical biology 20110411 |
| Acquired antifungal drug resistance in Aspergillus fumigatus: epidemiology and detection. | Medical mycology 20110401 |
| Trichosporon inkin Esophagitis: An Uncommon Disease in a Patient with Pulmonary Cancer. | Mycopathologia 20110401 |
| The value of amphotericin B in the treatment of invasive fungal infections. | Journal of critical care 20110401 |
| Commercial mouthwashes are more effective than azole antifungals against Candida albicans biofilms in vitro. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20110401 |
| Possible role of azole and echinocandin lock solutions in the control of Candida biofilms associated with silicone. | International journal of antimicrobial agents 20110401 |
| Synthesis and pharmacological evaluation of novel benzoylazole-based PPAR α/γ activators. | Bioorganic & medicinal chemistry letters 20110401 |
| CaIPF14030 negatively modulates intracellular ATP levels during the development of azole resistance in Candida albicans. | Acta pharmacologica Sinica 20110401 |
| Antimicrobial activity of a new combination system of benzimidazole and various azoles. | Archiv der Pharmazie 20110401 |
| New regulators of a high affinity Ca2+ influx system revealed through a genome-wide screen in yeast. | The Journal of biological chemistry 20110325 |
| Copper-catalyzed direct benzylation or allylation of 1,3-azoles with N-tosylhydrazones. | Journal of the American Chemical Society 20110316 |
| Pulmonary aspergillosis caused by a pan-azole-resistant Aspergillus fumigatus in a 10-year-old boy. | The Pediatric infectious disease journal 20110301 |
| Design and synthesis of novel tetrahydronaphthyl azoles and related cyclohexyl azoles as antileishmanial agents. | Bioorganic & medicinal chemistry letters 20110301 |
| Antifungal use in hospitalized adults in U.S. academic health centers. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110301 |
| Post-transcriptional defects of antioxidant selenoenzymes cause oxidative stress under methylmercury exposure. | The Journal of biological chemistry 20110225 |
| Structure of Ralstonia eutropha flavohemoglobin in complex with three antibiotic azole compounds. | Biochemistry 20110222 |
| Synthesis, modeling and evaluation of 3'-(1-aryl-1H-tetrazol-5-ylamino)-substituted 3'-deoxythymidine derivatives as potent and selective human mitochondrial thymidine kinase inhibitors. | Organic & biomolecular chemistry 20110207 |
| Use of external metabolizing systems when testing for endocrine disruption in the T-screen assay. | Toxicology and applied pharmacology 20110201 |
| Functional expression and characterization of CYP51 from dandruff-causing Malassezia globosa. | FEMS yeast research 20110201 |
| Low prevalence of resistance to azoles in Aspergillus fumigatus in a French cohort of patients treated for haematological malignancies. | The Journal of antimicrobial chemotherapy 20110201 |
| A Ritter-type reaction: direct electrophilic trifluoromethylation at nitrogen atoms using hypervalent iodine reagents. | Angewandte Chemie (International ed. in English) 20110201 |
| Overcoming the heterologous bias: an in vivo functional analysis of multidrug efflux transporter, CgCdr1p in matched pair clinical isolates of Candida glabrata. | Biochemical and biophysical research communications 20110107 |
| Antioxidants induce apoptosis of rat ovarian theca-interstitial cells. | Biology of reproduction 20110101 |
| Inhibitory effect of ebselen on lactate dehydrogenase activity from mammals: a comparative study with diphenyl diselenide and diphenyl ditelluride. | Drug and chemical toxicology 20110101 |
| Assessment of algorithms for predicting drug-drug interactions via inhibition mechanisms: comparison of dynamic and static models. | British journal of clinical pharmacology 20110101 |
| Targeted antioxidant therapies in hyperglycemia-mediated endothelial dysfunction. | Frontiers in bioscience (Scholar edition) 20110101 |
| Antimicrobial topical agents used in the vagina. | Current problems in dermatology 20110101 |
| Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata. | PloS one 20110101 |
| Epidemiology and antifungal resistance in invasive Aspergillosis according to primary disease: review of the literature. | European journal of medical research 20110101 |
| Effects of prevention of oxidative and nitro-oxidative stress on experimental rat colon anastomosis using acetylcysteine, Ebselen and 1400w. | Acta chirurgica Belgica 20110101 |
| In vivo activity of Sapindus saponaria against azole-susceptible and -resistant human vaginal Candida species. | BMC complementary and alternative medicine 20110101 |
| Beneficial effects of N-acetylcysteine and ebselen on renal ischemia/reperfusion injury. | Renal failure 20110101 |
| Neuroprotective effects of ebselen following forebrain ischemia: involvement of glutamate and nitric oxide. | Neurologia medico-chirurgica 20110101 |
| Synthesis of modified steroids as a novel class of non-ulcerogenic, anti-inflammatory and anti-nociceptive agents. | Steroids 20110101 |
| Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola. | PloS one 20110101 |
| Comparative drug susceptibility study of five clonal strains of Trichomonas vaginalis in vitro. | Asian Pacific journal of tropical medicine 20110101 |
| [Therapeutic efficacy of Triazavirin, a novel Russian chemotherapeutic, against influenza virus A (H5N1)]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101 |
| Dose-dependent protection on cisplatin-induced ototoxicity - an electrophysiological study on the effect of three antioxidants in the Sprague-Dawley rat animal model. | Medical science monitor : international medical journal of experimental and clinical research 20110101 |
| Targeting Trypanosoma cruzi sterol 14α-demethylase (CYP51). | Advances in parasitology 20110101 |
| Novel diphenylamine 2,4'-dicarboxamide based azoles as potential epidermal growth factor receptor inhibitors: synthesis and biological activity. | Chemical & pharmaceutical bulletin 20110101 |
| [Influence of rimantadine, ribavirine and triazavirine on influenza A virus replication in human monolayer and lymphoblastoid cell lines]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101 |
| Synthesis and structure of azole-fused indeno[2,1-c]quinolines and their anti-mycobacterial properties. | Organic & biomolecular chemistry 20101221 |
| Chain length effect on the binding of amphiphiles to serum albumin and to POPC bilayers. | The journal of physical chemistry. B 20101216 |
| Green synthesis and biological evaluation of some novel azoles as antimicrobial agents. | Bioorganic & medicinal chemistry letters 20101215 |
| Cu-catalyzed efficient synthetic methodology for ebselen and related Se-N heterocycles. | Organic letters 20101203 |
| Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse. | Diabetes 20101201 |
| Persistent Candida albicans colonization and molecular mechanisms of azole resistance in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients. | The Journal of antimicrobial chemotherapy 20101201 |
| Proteomic analysis of cytosolic proteins associated with petite mutations in Candida glabrata. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20101201 |
| Antifungal prophylaxis and therapy in patients with hematological malignancies and hematopoietic stem cell transplant recipients. | Expert review of anti-infective therapy 20101201 |
| Azole drugs trap cytochrome P450 EryK in alternative conformational states. | Biochemistry 20101102 |
| Complementation of a Saccharomyces cerevisiae ERG11/CYP51 (sterol 14α-demethylase) doxycycline-regulated mutant and screening of the azole sensitivity of Aspergillus fumigatus isoenzymes CYP51A and CYP51B. | Antimicrobial agents and chemotherapy 20101101 |
| Environmental study of azole-resistant Aspergillus fumigatus and other aspergilli in Austria, Denmark, and Spain. | Antimicrobial agents and chemotherapy 20101101 |
| A rapid and efficient route to benzazole heterocycles. | Nature protocols 20101101 |
| Pharmacological considerations for azole antifungal drug management in cystic fibrosis lung transplant patients. | Medical mycology 20101101 |
| Synthesis and in vitro anticancer activities of some selenadiazole derivatives. | Archiv der Pharmazie 20101101 |
| Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B. | Antimicrobial agents and chemotherapy 20101001 |
| In vitro activity of isavuconazole against 140 reference fungal strains and 165 clinically isolated yeasts from Japan. | International journal of antimicrobial agents 20101001 |
| Azole derivatives as histamine H3 receptor antagonists, part 2: C-C and C-S coupled heterocycles. | Bioorganic & medicinal chemistry letters 20101001 |
| Design of a series of bicyclic HIV-1 integrase inhibitors. Part 2: azoles: effective metal chelators. | Bioorganic & medicinal chemistry letters 20101001 |
| Azole derivatives as histamine H3 receptor antagonists, part I: thiazol-2-yl ethers. | Bioorganic & medicinal chemistry letters 20101001 |
| Azole antifungal resistance in Aspergillus fumigatus: 2008 and 2009. | The Journal of antimicrobial chemotherapy 20101001 |
| Cutaneous phaeohyphomycosis in renal allograft recipients: report of 2 cases and review of the literature. | Diagnostic microbiology and infectious disease 20101001 |
| Dynamics within site selectively templated and tagged xerogel sensor platforms. | Applied spectroscopy 20101001 |
| Cobalt-catalyzed addition of azoles to alkynes. | Organic letters 20100917 |
| Heme oxygenase inhibition by 1-aryl-2-(1h-imidazol-1-yl/1h-1,2,4-triazol-1-yl)ethanones and their derivatives. | ChemMedChem 20100903 |
| Interactions between antifungal and antiretroviral agents. | Expert opinion on drug safety 20100901 |
| Glutathione peroxidase-1 protects against cigarette smoke-induced lung inflammation in mice. | American journal of physiology. Lung cellular and molecular physiology 20100901 |
| Experimental murine scedosporiosis: histopathology and azole treatment. | Antimicrobial agents and chemotherapy 20100901 |
| Synthesis and biological activities of novel amine-derived bis-azoles as potential antibacterial and antifungal agents. | European journal of medicinal chemistry 20100901 |
| The serine/threonine protein phosphatase Sit4p activates multidrug resistance in Saccharomyces cerevisiae. | FEMS yeast research 20100901 |
| Functional characterization of the PP2C phosphatase CaPtc2p in the human fungal pathogen Candida albicans. | Yeast (Chichester, England) 20100901 |
| Reversal of stereoselectivity in the Cu-catalyzed conjugate addition reaction of dialkylzinc to cyclic enone in the presence of a chiral azolium compound. | The Journal of organic chemistry 20100820 |
| Synergistic anticandidal activity of pure polyphenol curcumin I in combination with azoles and polyenes generates reactive oxygen species leading to apoptosis. | FEMS yeast research 20100801 |
| Azole antimycotics and drug interactions in the perioperative period. | Current opinion in anaesthesiology 20100801 |
| Management of drug and food interactions with azole antifungal agents in transplant recipients. | Pharmacotherapy 20100801 |
| An enantioselective Claisen rearrangement catalyzed by N-heterocyclic carbenes. | Journal of the American Chemical Society 20100707 |
| The antifungal properties of chicken egg cystatin against Candida yeast isolates showing different levels of azole resistance. | Mycoses 20100701 |
| Impact of education and an antifungal stewardship program for candidiasis at a Thai tertiary care center. | Infection control and hospital epidemiology 20100701 |
| [Advances in the study of Candida albicans gene mutation on azole drug resistance]. | Yao xue xue bao = Acta pharmaceutica Sinica 20100701 |
| Diphenyl diselenide behaves differently than ebselen under different pH media in rat's liver preparations. | Pathology, research and practice 20100615 |
| Azole resistance in allergic bronchopulmonary aspergillosis and Aspergillus bronchitis. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100601 |
| Microbiological characteristics of clinical isolates of Cryptococcus neoformans in Taiwan: serotypes, mating types, molecular types, virulence factors, and antifungal susceptibility. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100601 |
| Phaeohyphomycosis due to Alternaria species in transplant recipients. | Transplant infectious disease : an official journal of the Transplantation Society 20100601 |
| Roles for Nox4 in the contractile response of bovine pulmonary arteries to hypoxia. | American journal of physiology. Heart and circulatory physiology 20100601 |
| New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triazole-5(4H)-thiones, and substituted hydrazides to the dicopper active site. | Bioorganic & medicinal chemistry 20100601 |
| Synthesis of a second generation chroman/catechol hybrids and evaluation of their activity in protecting neuronal cells from oxidative stress-induced cell death. | Bioorganic & medicinal chemistry 20100601 |
| In vitro synergistic interactions of the effects of various statins and azoles against some clinically important fungi. | FEMS microbiology letters 20100601 |
| Metal-free coupling of azoles with 2- and 3-haloindoles providing access to novel 2- or 3-(azol-1-yl)indole derivatives. | Organic letters 20100521 |
| Synthesis and in vitro and in vivo antifungal activity of the hydroxy metabolites of saperconazole. | ChemMedChem 20100503 |
| Effects of ebselen versus nimodipine on cerebral vasospasm subsequent to experimental subarachnoid hemorrhage in rats. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20100501 |
| Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives. | Bioorganic & medicinal chemistry letters 20100501 |
| [Therapy of candidemia and invasive candidiasis according to guidelines]. | Mycoses 20100501 |
| [Guideline based treatment of invasive aspergillosis]. | Mycoses 20100501 |
| Antifungal drug resistance: not all azoles are equal. | Expert review of anti-infective therapy 20100501 |
| Solid phase extraction--multisyringe flow injection system for the spectrophotometric determination of selenium with 2,3-diaminonaphthalene. | Talanta 20100415 |
| In vitro investigation of antifungal activity of allicin alone and in combination with azoles against Candida species. | Mycopathologia 20100401 |
| Exogenous and endogenous ceramides elicit volume-sensitive chloride current in ventricular myocytes. | Cardiovascular research 20100401 |
| Molecular aspects of azoles-induced teratogenesis. | Expert opinion on drug metabolism & toxicology 20100401 |
| Susceptibility to five antifungals of Aspergillus fumigatus strains isolated from chronically colonised cystic fibrosis patients receiving azole therapy. | International journal of antimicrobial agents 20100401 |
| Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes. | PLoS pathogens 20100401 |
| Ebselen reduces inflammation and microvascular perfusion failure after blunt skeletal muscle injury of the rat. | The Journal of trauma 20100401 |
| Invasive candidiasis in the intensive care unit. | Hospital practice (1995) 20100401 |
| Cloud point extraction and electrothermal atomic absorption spectrometry of Se (IV)--3,3'-diaminobenzidine for the estimation of trace amounts of Se (IV) and Se (VI) in environmental water samples and total selenium in animal blood and fish tissue samples. | Journal of hazardous materials 20100315 |
| Current concepts in systemic and topical therapy for superficial mycoses. | Clinics in dermatology 20100304 |
| Urban pigeons (Columba livia) as a potential source of pathogenic yeasts: a focus on antifungal susceptibility of Cryptococcus strains in Northeast Brazil. | Mycopathologia 20100301 |
| Structural characterization of human heme oxygenase-1 in complex with azole-based inhibitors. | Journal of inorganic biochemistry 20100301 |
| Improved model of lanosterol 14alpha-demethylase by ligand-supported homology modeling: validation by virtual screening and azole optimization. | ChemMedChem 20100301 |
| Prophylactic antifungal agents used after lung transplantation. | The Annals of pharmacotherapy 20100301 |
| 5-Selenization of salicylic acid derivatives yielded isoform-specific 5-lipoxygenase inhibitors. | Organic & biomolecular chemistry 20100221 |
| Determination of Se(IV) in natural waters by adsorptive stripping voltammetry of 5-nitropiazselenol. | Journal of hazardous materials 20100215 |
| Copper-catalyzed annulation of 2-formylazoles with o-aminoiodoarenes. | The Journal of organic chemistry 20100205 |
| Metabolic control of antifungal drug resistance. | Fungal genetics and biology : FG & B 20100201 |
| Inhibition of Candida albicans growth by brominated furanones. | Applied microbiology and biotechnology 20100201 |
| Photoinactivation of Candida albicans by its own endogenous porphyrins. | Current microbiology 20100201 |
| PAP1 [poly(A) polymerase 1] homozygosity and hyperadenylation are major determinants of increased mRNA stability of CDR1 in azole-resistant clinical isolates of Candida albicans. | Microbiology (Reading, England) 20100201 |
| Treatment of endemic mycoses. | Expert review of respiratory medicine 20100201 |
| The selenazal drug ebselen potently inhibits indoleamine 2,3-dioxygenase by targeting enzyme cysteine residues. | Biochemistry 20100126 |
| Opposing regulation of histamine-induced calcium signaling by sodium selenite and ebselen via alterations of thiol redox status. | European journal of pharmacology 20100125 |
| Synthesis and anti-viral activity of azolo-adamantanes against influenza A virus. | Bioorganic & medicinal chemistry 20100115 |
| NBD-based green fluorescent ligands for typing of thymine-related SNPs by using an abasic site-containing probe DNA. | Chembiochem : a European journal of chemical biology 20100104 |
| Treatment outcome of invasive mould disease after sequential exposure to azoles and liposomal amphotericin B. | The Journal of antimicrobial chemotherapy 20100101 |
| A new naphthimidazole derivative for saccharide labeling with enhanced sensitivity in mass spectrometry detection. | Rapid communications in mass spectrometry : RCM 20100101 |
| Synergistic mechanisms of retigeric acid B and azoles against Candida albicans. | Journal of applied microbiology 20100101 |
| In vitro activities of azole antifungal agents against Propionibacterium acnes isolated from patients with acne vulgaris. | Biological & pharmaceutical bulletin 20100101 |
| [Update: invasive fungal infections: Diagnosis and treatment in surgical intensive care medicine]. | Der Anaesthesist 20100101 |
| Expression, purification, and characterization of a recombinant neutral ceramidase from Mycobacterium tuberculosis. | Bioscience, biotechnology, and biochemistry 20100101 |
| Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence. | PloS one 20100101 |
| Expansion of ribosomally produced natural products: a nitrile hydratase- and Nif11-related precursor family. | BMC biology 20100101 |
| Antagonistic changes in sensitivity to antifungal drugs by mutations of an important ABC transporter gene in a fungal pathogen. | PloS one 20100101 |
| Development of specific inhibitors of CYP707A, a key enzyme in the catabolism of abscisic acid. | Current medicinal chemistry 20100101 |
| Candida albicans AGE3, the ortholog of the S. cerevisiae ARF-GAP-encoding gene GCS1, is required for hyphal growth and drug resistance. | PloS one 20100101 |
| Beyond ergosterol: linking pH to antifungal mechanisms. | Virulence 20100101 |
| [Triazavirin prophylactic efficacy against influenza virus A (H5N1)]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20100101 |
| Solution versus fluorous versus solid-phase synthesis of 2,5-disubstituted 1,3-azoles. Preliminary antibacterial activity studies. | The Journal of organic chemistry 20091204 |
| Comparative mechanisms of zearalenone and ochratoxin A toxicities on cultured HepG2 cells: is oxidative stress a common process? | Environmental toxicology 20091201 |
| The current role of amphotericin B lipid complex in managing systemic fungal infections. | Current medical research and opinion 20091201 |
| Azole-resistance in Aspergillus: proposed nomenclature and breakpoints. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20091201 |
| 2-Amino-nonyl-6-methoxyl-tetralin muriate inhibits sterol C-14 reductase in the ergosterol biosynthetic pathway. | Acta pharmacologica Sinica 20091201 |
| Inhibitory mechanism of novel inhibitors of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae. | Journal of microbiology and biotechnology 20091201 |
| Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II). | Chemical communications (Cambridge, England) 20091114 |
| Towards the mechanism and comparative effect of diphenyl diselenide, diphenyl ditelluride and ebselen under various pathophysiological conditions in rat's kidney preparation. | Chemico-biological interactions 20091110 |
| Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugs. | Molecular microbiology 20091101 |
| Neuroprotection of ebselen against ischemia/reperfusion injury involves GABA shunt enzymes. | Journal of the neurological sciences 20091015 |
| Discovery of highly potent novel antifungal azoles by structure-based rational design. | Bioorganic & medicinal chemistry letters 20091015 |
| New azoles with potent antifungal activity: design, synthesis and molecular docking. | European journal of medicinal chemistry 20091001 |
| Atypical Aspergillus flavus isolates associated with chronic azole therapy. | Journal of clinical microbiology 20091001 |
| Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD. | American journal of physiology. Heart and circulatory physiology 20091001 |
| Practical catalytic asymmetric synthesis of diaryl-, aryl heteroaryl-, and diheteroarylmethanols. | Journal of the American Chemical Society 20090902 |
| 3-imidazolyl-substituted flavans as potential antifungal agents: synthesis, stereochemical properties, and antifungal activity. | Archiv der Pharmazie 20090901 |
| New generation azole antifungals in clinical investigation. | Expert opinion on investigational drugs 20090901 |
| Structure-based and in silico design of Hsp90 inhibitors. | ChemMedChem 20090901 |
| A general copper-catalyzed coupling of azoles with vinyl bromides. | The Journal of organic chemistry 20090821 |
| In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes. | Antimicrobial agents and chemotherapy 20090801 |
| HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives. | Bioorganic & medicinal chemistry letters 20090801 |
| Erdosteine and ebselen as useful agents in intestinal ischemia/reperfusion injury. | The Journal of surgical research 20090801 |
| Role of Ndt80p in sterol metabolism regulation and azole resistance in Candida albicans. | Eukaryotic cell 20090801 |
| Hsp90 orchestrates stress response signaling governing fungal drug resistance. | PLoS pathogens 20090801 |
| The optimal wavelength of spectrophotometric broth microdilution antifungal susceptibility test for flucytosine and three azoles. | The Korean journal of laboratory medicine 20090801 |
| Seleniranium ion-triggered reactions: new aspects of Friedel-Crafts and N-detosylative cyclizations. | Organic letters 20090702 |
| Discrete generations of intracellular hydrogen peroxide and superoxide in antigen-stimulated mast cells: reciprocal regulation of store-operated Ca2+ channel activity. | Molecular immunology 20090701 |
| Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure. | Emerging infectious diseases 20090701 |
| Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. | PLoS pathogens 20090701 |
| Practical synthesis of a potent bradykinin B(1) antagonist via enantioselective hydrogenation of a pyridyl N-acyl enamide. | The Journal of organic chemistry 20090619 |
| Hollow fiber liquid phase microextraction followed by high performance liquid chromatography for determination of ultra-trace levels of Se(IV) after derivatization in urine, plasma and natural water samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090615 |
| Mutations in the CgPDR1 and CgERG11 genes in azole-resistant Candida glabrata clinical isolates from Slovakia. | International journal of antimicrobial agents 20090601 |
| Site-specific antiatherogenic effect of the antioxidant ebselen in the diabetic apolipoprotein E-deficient mouse. | Arteriosclerosis, thrombosis, and vascular biology 20090601 |
| Ibuprofen reverts antifungal resistance on Candida albicans showing overexpression of CDR genes. | FEMS yeast research 20090601 |
| Growth inhibitory action of ebselen on fluconazole-resistant Candida albicans: role of the plasma membrane H+-ATPase. | Microbial drug resistance (Larchmont, N.Y.) 20090601 |
| Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides. | FEMS microbiology letters 20090601 |
| [Antifungals for systemic use]. | Enfermedades infecciosas y microbiologia clinica 20090601 |
| Antagonists of the P2X(7) receptor. From lead identification to drug development. | Journal of medicinal chemistry 20090528 |
| Taguchi OA16 orthogonal array design for the optimization of cloud point extraction for selenium determination in environmental and biological samples by tungsten-modified tube electrothermal atomic absorption spectrometry. | Talanta 20090515 |
| Clinical relevance of the pharmacokinetic interactions of azole antifungal drugs with other coadministered agents. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090515 |
| Modeling the oxidation of ebselen and other organoselenium compounds using explicit solvent networks. | The journal of physical chemistry. A 20090514 |
| Ebselen attenuates cisplatin-induced ROS generation through Nrf2 activation in auditory cells. | Hearing research 20090501 |
| Antifungal drug resistance mechanisms. | Expert review of anti-infective therapy 20090501 |
| Azole-resistant central nervous system aspergillosis. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090415 |
| Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20090415 |
| Dependence of leukemic cell proliferation and survival on H2O2 and L-arginine. | Free radical biology & medicine 20090415 |
| In vitro activities of retigeric acid B alone and in combination with azole antifungal agents against Candida albicans. | Antimicrobial agents and chemotherapy 20090401 |
| Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance. | Antimicrobial agents and chemotherapy 20090401 |
| Overexpression of manganese superoxide dismutase in human dermal fibroblasts enhances the contraction of free floating collagen lattice: implications for ageing and hyperplastic scar formation. | Archives of dermatological research 20090401 |
| [Species-specific differences in Rhodamine 6G accumulation of Candida isolates detected by flow cytometric analysis]. | The Korean journal of laboratory medicine 20090401 |
| Ghrelin receptor modulators and their therapeutic potential. | Future medicinal chemistry 20090401 |
| The redox state of glutathione regulates the hypoxic induction of HIF-1. | European journal of pharmacology 20090315 |
| Enhancement of iron-catalyzed lipid peroxidation by acidosis in brain homogenate: comparative effect of diphenyl diselenide and ebselen. | Brain research 20090303 |
| Susceptibility of Candida albicans to common and novel antifungal drugs, and relationship between the mating type locus and resistance, in Lebanese hospital isolates. | Mycoses 20090301 |
| Oral candidiasis of HIV-infected children undergoing sequential HIV therapies. | Medical mycology 20090301 |
| Candida spp. in vitro susceptibility profile to four antifungal agents. Resistance surveillance study in Venezuelan strains. | Medical mycology 20090301 |
| Susceptibility testing of Cryptococcus diffluens against amphotericin B, flucytosine, fluconazole, itraconazole, voriconazole and posaconazole. | Medical mycology 20090301 |
| Redox modulation at the peripheral site alters nociceptive transmission in vivo. | Clinical and experimental pharmacology & physiology 20090301 |
| Multiple-azole-resistant Aspergillus fumigatus osteomyelitis in a patient with chronic granulomatous disease successfully treated with long-term oral posaconazole and surgery. | Medical mycology 20090301 |
| Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system. | Toxicology in vitro : an international journal published in association with BIBRA 20090301 |
| Design, synthesis and structure-activity relationships of azole acids as novel, potent dual PPAR alpha/gamma agonists. | Bioorganic & medicinal chemistry letters 20090301 |
| Modulation of the antifungal activity of new medicinal plant extracts active on Candida glabrata by the major transporters and regulators of the pleiotropic drug-resistance network in Saccharomyces cerevisiae. | Microbial drug resistance (Larchmont, N.Y.) 20090301 |
| Functional analysis of the Kluyveromyces lactis PDR1 gene. | FEMS yeast research 20090301 |
| Design of an assembly of poly(benzimidazole), carbon nanotubes, and Pt nanoparticles for a fuel-cell electrocatalyst with an ideal interfacial nanostructure. | Small (Weinheim an der Bergstrasse, Germany) 20090301 |
| New antifungal agents in pediatric practice. | Indian pediatrics 20090301 |
| Aqueous solvent system for the solubilization of azole compounds. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090215 |
| Design, synthesis and biological evaluation of a novel class of anticancer agents: anthracenylisoxazole lexitropsin conjugates. | Bioorganic & medicinal chemistry 20090215 |
| Synthesis, antitubercular activity and docking study of novel cyclic azole substituted diphenyl ether derivatives. | European journal of medicinal chemistry 20090201 |
| Pre-treatment with ebselen and vitamin E modulate acetylcholinesterase activity: interaction with demyelinating agents. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20090201 |
| Adoptive transfer of syngeneic bone marrow-derived cells in mice with obesity-induced diabetes: selenoorganic antioxidant ebselen restores stem cell competence. | The American journal of pathology 20090201 |
| Amyloidophilic compounds for prion diseases. | Infectious disorders drug targets 20090201 |
| Clinical indications for newer antifungal agents. | Journal of hospital medicine 20090201 |
| Fungal nail infections: diagnosis and management. | Prescrire international 20090201 |
| Threshold to N-methyl-D-aspartate-induced seizures in mice undergoing chronic nutritional magnesium deprivation is lowered in a way partly responsive to acute magnesium and antioxidant administrations. | The British journal of nutrition 20090201 |
| Antagonists of the human A(2A) adenosine receptor. 4. Design, synthesis, and preclinical evaluation of 7-aryltriazolo[4,5-d]pyrimidines. | Journal of medicinal chemistry 20090108 |
| Synthesis of telluroamino acid derivatives with remarkable GPx like activity. | Organic & biomolecular chemistry 20090107 |
| Antidepressant-like effect of the organoselenium compound ebselen in mice: evidence for the involvement of the monoaminergic system. | European journal of pharmacology 20090105 |
| Tetrahydronaphthyl azole oxime ethers: the conformationally rigid analogues of oxiconazole as antibacterials. | European journal of medicinal chemistry 20090101 |
| Azole resistance in Mycobacterium tuberculosis is mediated by the MmpS5-MmpL5 efflux system. | Tuberculosis (Edinburgh, Scotland) 20090101 |
| RTA2 is involved in calcineurin-mediated azole resistance and sphingoid long-chain base release in Candida albicans. | Cellular and molecular life sciences : CMLS 20090101 |
| International interlaboratory proficiency testing program for measurement of azole antifungal plasma concentrations. | Antimicrobial agents and chemotherapy 20090101 |
| Phosphine-free, palladium-catalyzed arylation of heterocycles through C-H bond activation with pivalic acid as a cocatalyst. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090101 |
| Ebselen improves ischemia-reperfusion injury after rat lung transplantation. | Lung 20090101 |
| Determination of azole antifungal medicines using zero-order and derivative UV spectrophotometry. | Acta poloniae pharmaceutica 20090101 |
| [Determination of 12 azole fungicide residues in beans and corn by offline disperse solid phase extraction and gas chromatography-negative chemical ionization mass spectrometry]. | Se pu = Chinese journal of chromatography 20090101 |
| Antifungal treatment for invasive Candida infections: a mixed treatment comparison meta-analysis. | Annals of clinical microbiology and antimicrobials 20090101 |
| Molecular differentiation and antifungal susceptibility of Candida albicans isolated from patients with respiratory infections in Guiyang Medical College Hospital, China. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20090101 |
| Detection and antifungal susceptibility testing of oral Candida dubliniensis from human immunodeficiency virus-infected patients. | Indian journal of pathology & microbiology 20090101 |
| Effects of N-acetylcysteine and ebselen on arachidonic acid release from astrocytes and neurons cultured in normoxic or simulated ischemic conditions. | Pharmacological reports : PR 20090101 |
| [Azole-resistant invasive aspergillosis]. | Nederlands tijdschrift voor geneeskunde 20090101 |
| How do azoles inhibit cytochrome P450 enzymes? A density functional study. | The journal of physical chemistry. A 20081218 |
| CYP51: A major drug target in the cytochrome P450 superfamily. | Lipids 20081201 |
| Covalent bonding of azoles to quaternary protoberberine alkaloids. | Magnetic resonance in chemistry : MRC 20081201 |
| [What's new in the molecular basis of antifungal drug resistance in pathogenic yeasts]. | Nihon rinsho. Japanese journal of clinical medicine 20081201 |
| [Cryptococcosis]. | Nihon rinsho. Japanese journal of clinical medicine 20081201 |
| [Potential of anidulafungin in hematological patients]. | Enfermedades infecciosas y microbiologia clinica 20081201 |
| [Potential of anidulafungin in combined therapy]. | Enfermedades infecciosas y microbiologia clinica 20081201 |
| Characterization of active site structure in CYP121. A cytochrome P450 essential for viability of Mycobacterium tuberculosis H37Rv. | The Journal of biological chemistry 20081128 |
| Design, synthesis, biological evaluation and pharmacokinetics of bis(hydroxyphenyl) substituted azoles, thiophenes, benzenes, and aza-benzenes as potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1). | Journal of medicinal chemistry 20081113 |
| 1,2,3-Triazol-carboxanilides and 1,2,3-triazol-(N-benzyl)-carboxamides as BK-potassium channel activators. XII. | European journal of medicinal chemistry 20081101 |
| Warfarin with fluoroquinolones, sulfonamides, or azole antifungals: interactions and the risk of hospitalization for gastrointestinal bleeding. | Clinical pharmacology and therapeutics 20081101 |
| A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus. | PLoS pathogens 20081101 |
| Emergence of azole resistance in Aspergillus fumigatus and spread of a single resistance mechanism. | PLoS medicine 20081101 |
| Ebselen attenuates cyclophosphamide-induced oxidative stress and DNA damage in mice. | Free radical research 20081101 |
| Activity of amphotericin B, anidulafungin, caspofungin, micafungin, posaconazole, and voriconazole against Candida albicans with decreased susceptibility to fluconazole from APECED patients on long-term azole treatment of chronic mucocutaneous candidiasis. | Diagnostic microbiology and infectious disease 20081001 |
| Subculture on potato dextrose agar as a complement to the broth microdilution assay for Malassezia pachydermatis. | Journal of microbiological methods 20081001 |
| Cytoplasmic localization of sterol transcription factors Upc2p and Ecm22p in S. cerevisiae. | Fungal genetics and biology : FG & B 20081001 |
| Absence of glutathione peroxidase-1 exacerbates cerebral ischemia-reperfusion injury by reducing post-ischemic microvascular perfusion. | Journal of neurochemistry 20081001 |
| Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus. | Antimicrobial agents and chemotherapy 20081001 |
| Azole fungicides: occurrence and fate in wastewater and surface waters. | Environmental science & technology 20081001 |
| The requirement of reactive oxygen intermediates for lymphocytic choriomeningitis virus binding and growth. | Virology 20080930 |
| Synthesis and antiviral activity of azoles obtained from carbohydrates. | Carbohydrate research 20080922 |
| RTA2, a novel gene involved in azole resistance in Candida albicans. | Biochemical and biophysical research communications 20080905 |
| Persistent pulmonary infection with an azole-resistant Coccidioides species. | Medical mycology 20080901 |
| A case of endocarditis caused by the yeast Pichia fabianii with biofilm production and developed in vitro resistance to azoles in the course of antifungal treatment. | Medical mycology 20080901 |
| Lipolytic and esterolytic activity-based profiling of murine liver. | Proteomics 20080901 |
| Candida albicans UPC2 is transcriptionally induced in response to antifungal drugs and anaerobicity through Upc2p-dependent and -independent mechanisms. | Microbiology (Reading, England) 20080901 |
| The structure of alkali metal derivatives of azoles: N-sigma versus pi structures. | The journal of physical chemistry. A 20080821 |
| Determination of physiological thiols by electrochemical detection with piazselenole and its application in rat breast cancer cells 4T-1. | Journal of the American Chemical Society 20080820 |
| Synthesis, structure, spectroscopic properties, and antiproliferative activity in vitro of novel osmium(III) complexes with azole heterocycles. | Inorganic chemistry 20080818 |
| Copper-mediated N-cyclopropylation of azoles, amides, and sulfonamides by cyclopropylboronic acid. | The Journal of organic chemistry 20080815 |
| Optimization of the central heterocycle of alpha-ketoheterocycle inhibitors of fatty acid amide hydrolase. | Journal of medicinal chemistry 20080814 |
| Micafungin activity against Candida albicans with diverse azole resistance phenotypes. | The Journal of antimicrobial chemotherapy 20080801 |
| Multilocus sequence typing confirms synonymy but highlights differences between Candida albicans and Candida stellatoidea. | FEMS yeast research 20080801 |
| Primary antifungal prophylaxis in hematopoietic stem cell transplant recipients: clinical implications of recent studies. | Current opinion in infectious diseases 20080801 |
| Hydrolysis and cytotoxic properties of osmium(II)/(III)-DMSO-azole complexes. Short communication. | Chemistry & biodiversity 20080801 |
| Copper complexes of anionic nitrogen ligands in the amidation and imidation of aryl halides. | Journal of the American Chemical Society 20080730 |
| Selenium compounds counteract the stimulation of ecto-nucleotidase activities in rat cultured cerebellar granule cells: putative correlation with neuroprotective effects. | Brain research 20080724 |
| Optimization of azoles as anti-human immunodeficiency virus agents guided by free-energy calculations. | Journal of the American Chemical Society 20080723 |
| Immunocompromised hosts: immunopharmacology of modern antifungals. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080715 |
| Synthesis, potent anti-staphylococcal activity and QSARs of some novel 2-anilinobenzazoles. | European journal of medicinal chemistry 20080701 |
| A phase 2, open-label study of the safety and efficacy of intravenous anidulafungin as a treatment for azole-refractory mucosal candidiasis. | Journal of acquired immune deficiency syndromes (1999) 20080701 |
| Design, synthesis and biological evaluation of bis(hydroxyphenyl) azoles as potent and selective non-steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases. | Bioorganic & medicinal chemistry 20080615 |
| Design, synthesis, characterization, antibacterial and antifungal activities of a novel class of 5,7-diaryl-4,4-dimethyl-4,5,6,7-tetrahydropyridino[3,4-d]-1,2,3-selenadiazoles. | Journal of enzyme inhibition and medicinal chemistry 20080601 |
| Protective effects of ebselen, a seleno-organic antioxidant on neurodegeneration induced by hypoxia and reperfusion in stroke-prone spontaneously hypertensive rat. | Neuroscience 20080502 |
| Semi-national surveillance of fungaemia in Denmark 2004-2006: increasing incidence of fungaemia and numbers of isolates with reduced azole susceptibility. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080501 |
| Genomewide location analysis of Candida albicans Upc2p, a regulator of sterol metabolism and azole drug resistance. | Eukaryotic cell 20080501 |
| Characterization of caspofungin susceptibilities by broth and agar in Candida albicans clinical isolates with characterized mechanisms of azole resistance. | Medical mycology 20080501 |
| New options for treatment of candidaemia in critically ill patients. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20080501 |
| Divergent functions of three Candida albicans zinc-cluster transcription factors (CTA4, ASG1 and CTF1) complementing pleiotropic drug resistance in Saccharomyces cerevisiae. | Microbiology (Reading, England) 20080501 |
| Cholesteryl ester hydroperoxides are biologically active components of minimally oxidized low density lipoprotein. | The Journal of biological chemistry 20080418 |
| Overanticoagulation with coumarin and cutaneous azole therapy. | Annals of internal medicine 20080415 |
| Ebselen attenuates cadmium-induced testicular damage in mice. | Journal of applied toxicology : JAT 20080401 |
| Endocrine-disrupting properties in vivo of widely used azole fungicides. | International journal of andrology 20080401 |
| An azole, an amide and a limonoid from Vepris uguenensis (Rutaceae). | Phytochemistry 20080401 |
| The ATP-binding cassette transporter-encoding gene CgSNQ2 is contributing to the CgPDR1-dependent azole resistance of Candida glabrata. | Molecular microbiology 20080401 |
| Synergistic activity of azoles with amiodarone against clinically resistant Candida albicans tested by chequerboard and time-kill methods. | Journal of medical microbiology 20080401 |
| Characterization of type II ligands in CYP2C9 and CYP3A4. | Journal of medicinal chemistry 20080327 |
| Involvement of peroxynitrite in pollen-induced nasal blockage in guinea pigs. | European journal of pharmacology 20080317 |
| Mechanistic studies of a palladium-catalyzed intramolecular hydroamination of unactivated alkenes: protonolysis of a stable palladium alkyl complex is the turnover-limiting step. | Journal of the American Chemical Society 20080305 |
| In vitro interaction between azoles and cyclosporin A against clinical isolates of Candida albicans determined by the chequerboard method and time-kill curves. | The Journal of antimicrobial chemotherapy 20080301 |
| Antioxidant and anti-mutagenic effects of ebselen in yeast and in cultured mammalian V79 cells. | Mutagenesis 20080301 |
| Ebselen increases cytosolic free Ca2+ concentration, stimulates glutamate release and increases GFAP content in rat hippocampal astrocytes. | Toxicology 20080227 |
| Rh(I)-catalyzed arylation of heterocycles via C-H bond activation: expanded scope through mechanistic insight. | Journal of the American Chemical Society 20080227 |
| Ebselen, a redox regulator containing a selenium atom, induces neurofilament M expression in cultured rat pheochromocytoma PC12 cells via activation of mitogen-activated protein kinase. | Journal of neuroscience research 20080215 |
| Aryl azoles with neuroprotective activity--parallel synthesis and attempts at target identification. | Bioorganic & medicinal chemistry 20080215 |
| Effect of substituents on the GPx-like activity of ebselen: steric versus electronic. | The journal of physical chemistry. A 20080207 |
| Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression. | Drug metabolism and disposition: the biological fate of chemicals 20080201 |
| Effects of fluorescent probe NBD-PC on the structure, dynamics and phase transition of DPPC. A molecular dynamics and differential scanning calorimetry study. | Biochimica et biophysica acta 20080201 |
| Azole antifungals induce up-regulation of SAP4, SAP5 and SAP6 secreted proteinase genes in filamentous Candida albicans cells in vitro and in vivo. | The Journal of antimicrobial chemotherapy 20080201 |
| Intermolecular hydroaminations via strained (E)-cycloalkenes. | The Journal of organic chemistry 20080201 |
| Total synthesis of thiopeptide antibiotics GE2270A, GE2270T, and GE2270C1. | Chemistry, an Asian journal 20080201 |
| Synthesis and anticandidal activity of azole-containing sulfonamides. | Archiv der Pharmazie 20080201 |
| [Successful treatment of azole-refractory Candida guilliermondii fungemia with a combination therapy of micafungin and liposomal amphotericin B]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20080201 |
| Antifungal serum concentration monitoring: an update. | The Journal of antimicrobial chemotherapy 20080101 |
| In vitro interactions between azoles and amiodarone against clinical Candida albicans. | International journal of antimicrobial agents 20080101 |
| 2-Hydroxyphenacyl azoles and related azolium derivatives as antifungal agents. | Bioorganic & medicinal chemistry letters 20080101 |
| 'Click' dendrimers: synthesis, redox sensing of Pd(OAc)2, and remarkable catalytic hydrogenation activity of precise Pd nanoparticles stabilized by 1,2,3-triazole-containing dendrimers. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
| Antifungal drugs. | Treatment guidelines from the Medical Letter 20080101 |
| Toward basic understanding of the partition coefficient log P and its application in QSAR. | SAR and QSAR in environmental research 20080101 |
| In search of the holy grail of antifungal therapy. | Transactions of the American Clinical and Climatological Association 20080101 |
| Antioxidant activity of the anti-inflammatory compound ebselen: a reversible cyclization pathway via selenenic and seleninic acid intermediates. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
| Alpha-lipoic acid and ebselen prevent ischemia/reperfusion injury in the rat intestine. | Surgery today 20080101 |
| Synthesis, characterization and antimicrobial activity of new 1,2,3-selenadiazoles. | Molecules (Basel, Switzerland) 20080101 |
| Reduction of vesicant toxicity by butylated hydroxyanisole in A-431 skin cells. | Cutaneous and ocular toxicology 20080101 |
| Molecular properties relevant to bioavailability of tioconazole and its derivatives. | Acta poloniae pharmaceutica 20080101 |
| Development of CXCR3 antagonists. Part 2: Identification of 2-amino(4-piperidinyl)azoles as potent CXCR3 antagonists. | Bioorganic & medicinal chemistry letters 20071215 |
| Regulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51. | The Journal of biological chemistry 20071214 |
| The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum. | The Journal of antimicrobial chemotherapy 20071201 |
| cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p. | Eukaryotic cell 20071201 |
| [Chronic ethanol feeding induces oxidative stress in the rat retina: treatment with the antioxidant ebselen]. | Archivos de la Sociedad Espanola de Oftalmologia 20071201 |
| Ebselen attenuates oxidative DNA damage and enhances its repair activity in the thalamus after focal cortical infarction in hypertensive rats. | Brain research 20071121 |
| Oxidative addition of 2-substituted azolium salts to Group-10 metal zero complexes--a DFT study. | Dalton transactions (Cambridge, England : 2003) 20071107 |
| Antifungal activity of statins against Aspergillus species. | Medical mycology 20071101 |
| Species distribution and susceptibility to azole antifungals of Candida bloodstream isolates from eight university hospitals in Korea. | Yonsei medical journal 20071031 |
| Copper(I)-catalyzed highly efficient synthesis of benzoselenazoles and benzotellurazoles. | The Journal of organic chemistry 20071012 |
| (45)Ca(2+) influx in rat brain: effect of diorganylchalcogenides compounds. | Toxicological sciences : an official journal of the Society of Toxicology 20071001 |
| Ebselen reduces nitration and restores voltage-gated potassium channel function in small coronary arteries of diabetic rats. | American journal of physiology. Heart and circulatory physiology 20071001 |
| Improved outcomes associated with advances in therapy for invasive fungal infections in immunocompromised hosts. | The Journal of infection 20071001 |
| Decreased susceptibility of Candida albicans to azole antifungals: a complication of long-term treatment in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients. | The Journal of antimicrobial chemotherapy 20071001 |
| Carbon monoxide stimulates the Ca2(+)-activated big conductance k channels in cultured human endothelial cells. | Hypertension (Dallas, Tex. : 1979) 20071001 |
| 3,3'-diselenodipropionic acid, an efficient peroxyl radical scavenger and a GPx mimic, protects erythrocytes (RBCs) from AAPH-induced hemolysis. | Chemical research in toxicology 20071001 |
| Synthesis and biological evaluation of 3-(azolylmethyl)-1H-indoles and 3-(alpha-azolylbenzyl)-1H-indoles as selective aromatase inhibitors. | Journal of enzyme inhibition and medicinal chemistry 20071001 |
| Dynamics of membrane protein/amphipol association studied by Förster resonance energy transfer: implications for in vitro studies of amphipol-stabilized membrane proteins. | Biochemistry 20070911 |
| Azole therapy of clinical and experimental coccidioidomycosis. | Annals of the New York Academy of Sciences 20070901 |
| Chemotherapeutic evaluation of alginate nanoparticle-encapsulated azole antifungal and antitubercular drugs against murine tuberculosis. | Nanomedicine : nanotechnology, biology, and medicine 20070901 |
| The diverse chemistry of oxazol-5-(4H)-ones. | Chemical Society reviews 20070901 |
| Surface modification of cetyltrimethylammonium bromide-capped gold nanorods to make molecular probes. | Langmuir : the ACS journal of surfaces and colloids 20070814 |
| Synthesis and evaluation of novel 1-(1H-1,2,4-triazol-1-yl)-2-(2,4-difluorophenyl)-3-[(4-substitutedphenyl)-piperazin-1-yl]-propan-2-ols as antifungal agents. | European journal of medicinal chemistry 20070801 |
| Lung toxicity of nitrogen mustard may be mediated by nitric oxide and peroxynitrite in rats. | Research in veterinary science 20070801 |
| Treatment of acute Old World cutaneous leishmaniasis: a systematic review of the randomized controlled trials. | Journal of the American Academy of Dermatology 20070801 |
| Enantioselective separation of azole compounds by EKC. Reversal of migration order of enantiomers with CD concentration. | Electrophoresis 20070801 |
| Novel inhibitors of VEGF receptors-1 and -2 based on azole-5-carboxamide templates. | Bioorganic & medicinal chemistry letters 20070701 |
| Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae. | Eukaryotic cell 20070701 |
| Identification of Y118 amino acid residue in Candida albicans sterol 14alpha-demethylase associated with the enzyme activity and selective antifungal activity of azole analogues. | Biological & pharmaceutical bulletin 20070701 |
| Previous treatment with ebselen and vitamin E alters adenine nucleotide hydrolysis in platelets from adult rats experimentally demyelinated with ethidium bromide. | Life sciences 20070627 |
| Diverse functionalization of thiazolo ring-fused 2-pyridones. | The Journal of organic chemistry 20070622 |
| Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP). | Bioorganic & medicinal chemistry letters 20070615 |
| Ebselen and diorganylchalcogenides decrease in vitro glutamate uptake by rat brain slices: prevention by DTT and GSH. | Toxicology in vitro : an international journal published in association with BIBRA 20070601 |
| Synthesis of azole nucleoside analogues of D-pinitol as potential antitumor agents. | Carbohydrate research 20070507 |
| Monitoring the looping up of acyl chain labeled NBD lipids in membranes as a function of membrane phase state. | Biochimica et biophysica acta 20070501 |
| Deficient peroxide detoxification underlies the susceptibility of oligodendrocyte progenitors to dopamine toxicity. | Neuropharmacology 20070501 |
| Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformans. | Molecular microbiology 20070501 |
| Transmembrane transport of peptidoglycan precursors across model and bacterial membranes. | Molecular microbiology 20070501 |
| Ebselen protects brain, skin, lung and blood cells from mechlorethamine toxicity. | Toxicology and industrial health 20070501 |
| Density functional theory study of the reaction mechanism and energetics of the reduction of hydrogen peroxide by ebselen, ebselen diselenide, and ebselen selenol. | The journal of physical chemistry. A 20070426 |
| Ebselen treatment reduces noise induced hearing loss via the mimicry and induction of glutathione peroxidase. | Hearing research 20070401 |
| Role of endogenous hydrogen peroxide in the development of nitrate tolerance. | Vascular pharmacology 20070401 |
| Antifungal susceptibility of 1000 Candida bloodstream isolates to 5 antifungal drugs: results of a multicenter study conducted in São Paulo, Brazil, 1995-2003. | Diagnostic microbiology and infectious disease 20070401 |
| Synthesis and antibacterial activity of some 5-(4-biphenylyl)-7-aryl [3,4-d]-1,2,3-benzoselenadiazoles. | Journal of enzyme inhibition and medicinal chemistry 20070401 |
| Enantiomeric separation of several antimycotic azole drugs using supercritical fluid chromatography. | Journal of chromatography. A 20070316 |
| Location and dynamics of acyl chain NBD-labeled phosphatidylcholine (NBD-PC) in DPPC bilayers. A molecular dynamics and time-resolved fluorescence anisotropy study. | Biochimica et biophysica acta 20070301 |
| ortho-Substituted azoles as selective and dual inhibitors of VEGF receptors 1 and 2. | Bioorganic & medicinal chemistry letters 20070301 |
| Spontaneous, intervesicular transfer rates of fluorescent, acyl chain-labeled phosphatidylcholine analogs. | Biochimica et biophysica acta 20070301 |
| Differential reactivity of alpha and beta 2'-deoxyribonucleosides towards protonation and metalation. | Journal of inorganic biochemistry 20070301 |
| Antifungal activities of azole agents against the Malassezia species. | International journal of antimicrobial agents 20070301 |
| Ebselen prevents chronic alcohol-induced rat hippocampal stress and functional impairment. | Alcoholism, clinical and experimental research 20070301 |
| [Mechanisms of resistance to antifungal agents]. | Nihon rinsho. Japanese journal of clinical medicine 20070227 |
| N-Acetylcysteine and ebselen but not nifedipine protected cerebellar granule neurons against 4-hydroxynonenal-induced neuronal death. | Neuroscience research 20070201 |
| Synthesis, characterization, and antioxidant activity of some ebselen analogues. | Chemistry (Weinheim an der Bergstrasse, Germany) 20070101 |
| Antifungal drug susceptibility of Cryptococcus neoformans from clinical sources in Nairobi, Kenya. | Mycoses 20070101 |
| Voriconazole resistant Candida spp. and Saccharomyces spp. isolates from oropharyngeal candidiasis from Cambodian children with AIDS not pretreated with azoles (letter). | Scandinavian journal of infectious diseases 20070101 |
| [The role of sterols in morphogenetic processes and dimorphism in fungi]. | Mikrobiologiia 20070101 |
| Fluorescent fructose derivatives for imaging breast cancer cells. | Bioconjugate chemistry 20070101 |
| Synthesis and evaluation of new difluoromethyl azoles as antileishmanial agents. | European journal of medicinal chemistry 20070101 |
| Safety and efficacy of posaconazole in the long-term treatment of azole-refractory oropharyngeal and esophageal candidiasis in patients with HIV infection. | HIV clinical trials 20070101 |
| Synthesis of novel N-rich polycyclic skeletons based on azoles and pyridines. | Journal of combinatorial chemistry 20070101 |
| A method for determination of selenium in organic tissues using microwave digestion and liquid chromatography. | Journal of AOAC International 20070101 |
| Discovery and development of ATPase inhibitors of DNA gyrase as antibacterial agents. | Current medicinal chemistry 20070101 |
| New noninvasive methodology for real-time monitoring of lipid flip. | Bioconjugate chemistry 20070101 |
| [Treatment of fungal infections of upper respiratory tract and ear]. | Otolaryngologia polska = The Polish otolaryngology 20070101 |
| Evaluation of the antimicrobial activity of ebselen: role of the yeast plasma membrane H+-ATPase. | Journal of biochemical and molecular toxicology 20070101 |
| Effects of ebselen on glutathione level in neurons exposed to arachidonic acid and 4-hydroxynonenal during simulated ischemia in vitro. | Pharmacological reports : PR 20070101 |
| Species distribution and susceptibility to azoles of vaginal yeasts isolated prostitutes. | Infectious diseases in obstetrics and gynecology 20070101 |
| [Investigation of triazavirin antiviral activity against influenza A virus (H5N1) in cell culture]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101 |
| Crystal structure of the Mycobacterium tuberculosis P450 CYP121-fluconazole complex reveals new azole drug-P450 binding mode. | The Journal of biological chemistry 20061222 |
| CYP121, CYP51 and associated redox systems in Mycobacterium tuberculosis: towards deconvoluting enzymology of P450 systems in a human pathogen. | Biochemical Society transactions 20061201 |
| Factors influencing the magnitude and clinical significance of drug interactions between azole antifungals and select immunosuppressants. | Pharmacotherapy 20061201 |
| Cardioprotective effects of subcutaneous ebselen against daunorubicin-induced cardiomyopathy in rats. | Basic & clinical pharmacology & toxicology 20061201 |
| Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. | Toxicology 20061110 |
| Diphenyl diselenide reduces temporarily hyperglycemia: possible relationship with oxidative stress. | Chemico-biological interactions 20061107 |
| Ebselen effects on MPTP-induced neurotoxicity. | Brain research 20061106 |
| In vitro activity and synergism of amphotericin B, azoles and cationic antimicrobials against the emerging pathogen Trichoderma spp. | The Journal of antimicrobial chemotherapy 20061101 |
| Oral pretreatment with ebselen enhances heat shock protein 72 expression and reduces myocardial infarct size. | Hypertension research : official journal of the Japanese Society of Hypertension 20061101 |
| Horseradish peroxidase inhibition and antioxidant activity of ebselen and related organoselenium compounds. | Bioorganic & medicinal chemistry letters 20061015 |
| Inexpensive, one-pot synthesis of unsymmetrical disulfides using 1-chlorobenzotriazole. | The Journal of organic chemistry 20061013 |
| Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2. | Molecular microbiology 20061001 |
| Oxidative stress induces ADAM9 protein expression in human prostate cancer cells. | Cancer research 20061001 |
| Role of enteral nutrition supplemented with ebselen and EHEC in pancreatitis-associated multiple organ dysfunction in rats. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20061001 |
| Inhibition of caspase-dependent mitochondrial permeability transition protects airway epithelial cells against mustard-induced apoptosis. | Apoptosis : an international journal on programmed cell death 20060901 |
| Protective effect of ebselen, a selenoorganic drug, against gentamicin-induced renal damage in rats. | Basic & clinical pharmacology & toxicology 20060901 |
| Ebselen, a seleno-organic antioxidant, as an electrophile. | Chemical research in toxicology 20060901 |
| Small-molecule screening identifies the selanazal drug ebselen as a potent inhibitor of DMT1-mediated iron uptake. | Chemistry & biology 20060901 |
| Effect of selenium compounds on the damage induced by oxysterol on rat arterial walls. | Biological trace element research 20060901 |
| Reactive oxygen species mediate phorbol ester-stimulated cAMP response in human eosinophils. | European journal of pharmacology 20060814 |
| Cloning and characterization of CYP51 from Mycobacterium avium. | American journal of respiratory cell and molecular biology 20060801 |
| Proteomic analysis of experimentally induced azole resistance in Candida glabrata. | The Journal of antimicrobial chemotherapy 20060801 |
| Caspofungin activity against clinical isolates of azole cross-resistant Candida glabrata overexpressing efflux pump genes. | The Journal of antimicrobial chemotherapy 20060801 |
| Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome-wide expression studies. | Molecular microbiology 20060801 |
| Treatment options of invasive fungal infections in adults. | Swiss medical weekly 20060722 |
| Aneuploidy and isochromosome formation in drug-resistant Candida albicans. | Science (New York, N.Y.) 20060721 |
| Modeling the reduction of hydrogen peroxide by glutathione peroxidase mimics. | The journal of physical chemistry. A 20060720 |
| Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen. | Brain : a journal of neurology 20060701 |
| Classical QSAR study on chromene derivatives as lanosterol 14alpha- demethylase inhibitor: a non azole antifungal target. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20060701 |
| Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense. | Journal of natural products 20060701 |
| A new non-azole inhibitor of ABA 8'-hydroxylase: effect of the hydroxyl group substituted for geminal methyl groups in the six-membered ring. | Bioorganic & medicinal chemistry letters 20060615 |
| Direct assay for alpha-amylase using fluorophore-modified cyclodextrins. | Bioorganic & medicinal chemistry 20060601 |
| Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans. | The Journal of antimicrobial chemotherapy 20060601 |
| In vitro antifungal susceptibility to six antifungal agents of 229 Candida isolates from patients with diabetes mellitus. | Oral microbiology and immunology 20060601 |
| Design of clinical trials of empiric antifungal therapy in patients with persistent febrile neutropenia: considerations and critiques. | Pharmacotherapy 20060601 |
| Treatment options for invasive fungal infections. | Pharmacotherapy 20060601 |
| Emerging antifungal azoles and effects on Magnaporthe grisea. | Mycological research 20060601 |
| PDR16-mediated azole resistance in Candida albicans. | Molecular microbiology 20060601 |
| Measuring translocation of fluorescent lipid derivatives across yeast Golgi membranes. | Methods (San Diego, Calif.) 20060601 |
| Antileishmanial activities and mechanisms of action of indole-based azoles. | Journal of enzyme inhibition and medicinal chemistry 20060601 |
| Synthesis and antifungal activity of new thienyl and aryl conazoles. | Journal of enzyme inhibition and medicinal chemistry 20060601 |
| Solid-phase synthesis of 1,3-azole-based peptides and peptidomimetics. | Organic letters 20060525 |
| Neuroprotective effects of ebselen are associated with the regulation of Bcl-2 and Bax proteins in cultured mouse cortical neurons. | Neuroscience letters 20060522 |
| Nitric oxide inhibits HIF-1alpha protein accumulation under hypoxic conditions: implication of 2-oxoglutarate and iron. | Biochimie 20060501 |
| Synthesis and antifungal activities of some aryl [3-(imidazol-1-yl/triazol-1-ylmethyl) benzofuran-2-yl] ketoximes. | European journal of medicinal chemistry 20060501 |
| Diphenyl ditelluride- and methylmercury-induced hyperphosphorilation of the high molecular weight neurofilament subunit is prevented by organoselenium compounds in cerebral cortex of young rats. | Toxicology 20060501 |
| Ebselen induced C6 glioma cell death in oxygen and glucose deprivation. | Chemical research in toxicology 20060501 |
| Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking. | Journal of medicinal chemistry 20060420 |
| Drug interactions during therapy with three major groups of antimicrobial agents. | Expert opinion on pharmacotherapy 20060401 |
| Pharmaceutical prescribing for children. Part 4. Antifungal and antiviral therapy. | Primary dental care : journal of the Faculty of General Dental Practitioners (UK) 20060401 |
| Effect of azoles on the secretion of a Candida albicans metallopeptidase. | Mycopathologia 20060301 |
| Protective effect of ebselen on cytotoxicity induced by cholestane-3 beta, 5 alpha, 6 beta-triol in ECV-304 cells. | Biochimica et biophysica acta 20060301 |
| Substituent effects on enthalpies of formation of nitrogen heterocycles: 2-substituted benzimidazoles and related compounds. | The journal of physical chemistry. A 20060223 |
| Inhibition of human CYP19 by azoles used as antifungal agents and aromatase inhibitors, using a new LC-MS/MS method for the analysis of estradiol product formation. | Toxicology 20060215 |
| Immobilization stress induces cell death through production of reactive oxygen species in the mouse cerebral cortex. | Neuroscience letters 20060109 |
| Beneficial effects of Ebselen on corrosive esophageal burns of rats. | International journal of pediatric otorhinolaryngology 20060101 |
| Peroxynitrite reduces the endothelium-derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knockout mice. | American journal of physiology. Regulatory, integrative and comparative physiology 20060101 |
| Lifetime fluorescence method for determining membrane topology of proteins. | Analytical biochemistry 20060101 |
| In vitro activities of caspofungin, amphotericin B and azoles against Coccidioides posadasii strains from Northeast, Brazil. | Mycopathologia 20060101 |
| The statins: drug interactions of significance to the dental practitioner. | Dental update 20060101 |
| Ebselen attenuates oxidative stress in ischemic astrocytes depleted of glutathione. Comparison with glutathione precursors. | Pharmacological reports : PR 20060101 |
| The protective effects of selenoorganic compounds against peroxynitrite-induced changes in plasma proteins and lipids. | Cellular & molecular biology letters 20060101 |
| Limitations of caspofungin in the treatment of obstructive pyonephrosis due to Candida glabrata infection. | BMC infectious diseases 20060101 |
| [Studies on the correlation of the method currently used by the Japanese Society for Medical Mycology and its modified method with the NCCLS M27-A2 microdilution method for azole susceptibility testing of Candida species]. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20060101 |
| A new, broad-spectrum azole antifungal: posaconazole--mechanisms of action and resistance, spectrum of activity. | Mycoses 20060101 |
| [Antifungals cellular targets and mechanisms of resistance]. | Therapie 20060101 |
| [Emerging azole antifungals]. | Therapie 20060101 |
| In vivo activity of terpinen-4-ol, the main bioactive component of Melaleuca alternifolia Cheel (tea tree) oil against azole-susceptible and -resistant human pathogenic Candida species. | BMC infectious diseases 20060101 |
| Design and biological evaluation of photo-switchable inhibitors. | Genome informatics. International Conference on Genome Informatics 20060101 |
| Current status and future of antifungal therapy for systemic mycoses. | Recent patents on anti-infective drug discovery 20060101 |
| Analysis of pesticides in fruits by pressurized liquid extraction and liquid chromatography-ion trap-triple stage mass spectrometry. | Journal of chromatography. A 20051209 |
| Skeleton-selective fluorescent chemosensor based on cyclodextrin bearing a 4-amino-7-nitrobenz-2-oxa-1,3-diazole moiety. | Organic & biomolecular chemistry 20051207 |
| Endothelin mediates superoxide production and vasoconstriction through activation of NADPH oxidase and uncoupled nitric-oxide synthase in the rat aorta. | The Journal of pharmacology and experimental therapeutics 20051201 |
| Current state of three-dimensional characterisation of antifungal targets and its use for molecular modelling in drug design. | International journal of antimicrobial agents 20051201 |
| Identification of the structural requirements of the receptor-binding affinity of diphenolic azoles to estrogen receptors alpha and beta by three-dimensional quantitative structure-activity relationship and structure-activity relationship analysis. | Journal of medicinal chemistry 20051201 |
| Design, synthesis, and microbiological evaluation of new Candida albicans CYP51 inhibitors. | Journal of medicinal chemistry 20051201 |
| Fungal infections of the skin: infection process and antimycotic therapy. | Current drug targets 20051201 |
| Currently used antimycotics: spectrum, mode of action and resistance occurrence. | Current drug targets 20051201 |
| Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na(+), K(+)-ATPase activity in rats. | Toxicology 20051115 |
| Frequency of potential azole drug-drug interactions and consequences of potential fluconazole drug interactions. | Pharmacoepidemiology and drug safety 20051101 |
| Peroxynitrite hyperpolarizes smooth muscle and relaxes internal carotid artery in rabbit via ATP-sensitive K+ channels. | American journal of physiology. Heart and circulatory physiology 20051101 |
| Azole susceptibility and resistance in Candida dubliniensis. | Biochemical Society transactions 20051101 |
| Metal ion coordination to azole nucleosides. | Chemistry (Weinheim an der Bergstrasse, Germany) 20051021 |
| Ebselen protects glutamate uptake inhibition caused by methyl mercury but does not by Hg2+. | Toxicology 20051015 |
| Compounds for the prevention and treatment of noise-induced hearing loss. | Drug discovery today 20051001 |
| Versatile access to C-4-substituted 2-amino-1,3-azoles from hydropyridines in oxidative conditions. | The Journal of organic chemistry 20050930 |
| New multi-1,2,3-selenadiazole aromatic derivatives. | Molecules (Basel, Switzerland) 20050930 |
| Nano-encapsulation of azole antifungals: potential applications to improve oral drug delivery. | International journal of pharmaceutics 20050914 |
| Ebselen: a thioredoxin reductase-dependent catalyst for alpha-tocopherol quinone reduction. | Toxicology and applied pharmacology 20050901 |
| Recent developments in cannabinoid ligands. | Life sciences 20050819 |
| Glutathione peroxidase (GPx)-like antioxidant activity of the organoselenium drug ebselen: unexpected complications with thiol exchange reactions. | Journal of the American Chemical Society 20050817 |
| Quantitation of 13 azole fungicides in wine samples by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. A 20050812 |
| Sterol uptake in Candida glabrata: rescue of sterol auxotrophic strains. | Diagnostic microbiology and infectious disease 20050801 |
| Synthesis, characterization and biological activity of triorganotin 2-phenyl-1,2,3-triazole-4-carboxylates. | Journal of inorganic biochemistry 20050801 |
| Antifungal treatment in pediatric patients. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20050801 |
| Aspirochlorine class compounds from Aspergillus flavus inhibit azole-resistant Candida albicans. | Journal of natural products 20050801 |
| CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions. | The Journal of pharmacology and experimental therapeutics 20050701 |
| Ebselen attenuates haloperidol-induced orofacial dyskinesia and oxidative stress in rat brain. | Pharmacology, biochemistry, and behavior 20050701 |
| NADPH oxidase is required for NMDA receptor-dependent activation of ERK in hippocampal area CA1. | Journal of neurochemistry 20050701 |
| Synthesis and characterization of a triphenylphosphonium-conjugated peroxidase mimetic. Insights into the interaction of ebselen with mitochondria. | The Journal of biological chemistry 20050624 |
| Ebselen prevents noise-induced excitotoxicity and temporary threshold shift. | Neuroscience letters 20050603 |
| Synthesis and characterization of azole isoflavone inhibitors of aromatase. | Bioorganic & medicinal chemistry 20050602 |
| Organoselenium compounds prevent hyperphosphorylation of cytoskeletal proteins induced by the neurotoxic agent diphenyl ditelluride in cerebral cortex of young rats. | Toxicology 20050601 |
| Combined oral delivery of ebselen and allopurinol reduces multiple cisplatin toxicities in rat breast and ovarian cancer models while enhancing anti-tumor activity. | Anti-cancer drugs 20050601 |
| Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans. | Antimicrobial agents and chemotherapy 20050601 |
| Antifungal activities of tacrolimus and azole agents against the eleven currently accepted Malassezia species. | Journal of clinical microbiology 20050601 |
| Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs. | The Journal of pharmacy and pharmacology 20050601 |
| Determination of azolic fungicides in wine by solid-phase extraction and high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry. | Journal of chromatography. A 20050527 |
| Selenium compounds prevent the effects of methylmercury on the in vitro phosphorylation of cytoskeletal proteins in cerebral cortex of young rats. | Toxicological sciences : an official journal of the Society of Toxicology 20050501 |
| Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes. | The Journal of antimicrobial chemotherapy 20050501 |
| Peroxynitrite may be involved in bladder damage caused by cyclophosphamide in rats. | The Journal of urology 20050501 |
| Effects of Y132H and F145L substitutions on the activity, azole resistance and spectral properties of Candida albicans sterol 14-demethylase P450 (CYP51): a live example showing the selection of altered P450 through interaction with environmental compounds. | Journal of biochemistry 20050501 |
| Azole and fungicide resistance in clinical and environmental Aspergillus fumigatus isolates. | Medical mycology 20050501 |
| The ergosterol biosynthesis pathway, transporter genes, and azole resistance in Aspergillus fumigatus. | Medical mycology 20050501 |
| Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model. | Journal of medicinal chemistry 20050421 |
| Regulation of azole drug susceptibility by Candida albicans protein kinase CK2. | Molecular microbiology 20050401 |
| Free radical trapping as a therapeutic approach to neuroprotection in stroke: experimental and clinical studies with NXY-059 and free radical scavengers. | Current drug targets. CNS and neurological disorders 20050401 |
| Effect of ebselen and organochalcogenides on excitotoxicity induced by glutamate in isolated chick retina. | Brain research 20050328 |
| Structural diversities of active site in clinical azole-bound forms between sterol 14alpha-demethylases (CYP51s) from human and Mycobacterium tuberculosis. | The Journal of biological chemistry 20050311 |
| Reduction of acute cisplatin ototoxicity and nephrotoxicity in rats by oral administration of allopurinol and ebselen. | Hearing research 20050301 |
| Synthesis and spectroscopic characterisation of new ESIPT fluorescent protein probes. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050301 |
| [Synthesis of byrazoline fluorescent compounds and studies by infrared spectroscopy]. | Guang pu xue yu guang pu fen xi = Guang pu 20050301 |
| Neuroprotective effects of ebselen on experimental spinal cord injury in rats. | Neurochemical research 20050301 |
| Protective effect of antioxidant ebselen (PZ51) on the cerebral cortex of stroke-prone spontaneously hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20050301 |
| New agents for invasive mycoses in children. | Current opinion in pediatrics 20050201 |
| Antifungal drugs. | Treatment guidelines from the Medical Letter 20050201 |
| Mechanisms of azole resistance in clinical isolates of Candida glabrata collected during a hospital survey of antifungal resistance. | Antimicrobial agents and chemotherapy 20050201 |
| Involvement of peroxynitrite in capsaicin-induced apoptosis of C6 glioma cells. | Neuroscience research 20050201 |
| Emerging azole antifungals. | Expert opinion on emerging drugs 20050201 |
| Second-generation azole antifungal agents. | Drugs of today (Barcelona, Spain : 1998) 20050201 |
| Hypoxia-induced dysfunction of rat diaphragm: role of peroxynitrite. | American journal of physiology. Lung cellular and molecular physiology 20050101 |
| Solid-phase synthesis of 5-amino-1-(substituted thiocarbamoyl)pyrazole and 1,2,4-triazole derivatives via dithiocarbazate linker. | Journal of combinatorial chemistry 20050101 |
| Characterization and properties of cholesterol desaturases from the ciliate Tetrahymena thermophila. | The Journal of eukaryotic microbiology 20050101 |
| Kinetic studies of the radical-scavenging activity of ebselen, a seleno-organic compound. | Anticancer research 20050101 |
| [Synthesis and antiviral activity of new 5-substituted 2'-deoxyuridine derivatives]. | Bioorganicheskaia khimiia 20050101 |
| Effect of glutathione peroxidase mimic ebselen (PZ51) on endothelium and vascular structure of stroke-prone spontaneously hypertensive rats. | Blood pressure 20050101 |
| Glyoxylic acid and MP-glyoxylate: efficient formaldehyde equivalents in the 3-CC of 2-aminoazines, aldehydes, and isonitriles. | Organic letters 20041223 |
| Oral Candida isolates in patients undergoing radiotherapy for head and neck cancer: prevalence, azole susceptibility profiles and response to antifungal treatment. | Oral microbiology and immunology 20041201 |
| Endothelial dysfunction as a modifier of angiogenic response in Zucker diabetic fat rat: amelioration with Ebselen. | Kidney international 20041201 |
| TAC1, transcriptional activator of CDR genes, is a new transcription factor involved in the regulation of Candida albicans ABC transporters CDR1 and CDR2. | Eukaryotic cell 20041201 |
| The effects of ebselen on [3H]glutamate uptake by synaptic vesicles from rat brain. | Brain research 20041119 |
| Protective effects on neuronal cells of mouse afforded by ebselen against oxidative stress at multiple steps. | Neuroscience letters 20041116 |
| Ebselen augments its peroxidase activity by inducing nrf-2-dependent transcription. | Archives of biochemistry and biophysics 20041115 |
| Combinations of antifungal agents in therapy--what value are they? | The Journal of antimicrobial chemotherapy 20041101 |
| Synthesis and antibacterial activity of novel and potent DNA gyrase inhibitors with azole ring. | Bioorganic & medicinal chemistry 20041101 |
| Potent antitumor activity of novel iron chelators derived from di-2-pyridylketone isonicotinoyl hydrazone involves fenton-derived free radical generation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041101 |
| Azaanalogues of ebselen as antimicrobial and antiviral agents: synthesis and properties. | Farmaco (Societa chimica italiana : 1989) 20041101 |
| Combination antifungal therapy: where are we now, and where are we going? | Oncology (Williston Park, N.Y.) 20041101 |
| Thermodynamic and biophysical characterization of cytochrome P450 BioI from Bacillus subtilis. | Biochemistry 20041005 |
| Oxidant activity in skeletal muscle fibers is influenced by temperature, CO2 level, and muscle-derived nitric oxide. | American journal of physiology. Regulatory, integrative and comparative physiology 20041001 |
| Posaconazole is a potent inhibitor of sterol 14alpha-demethylation in yeasts and molds. | Antimicrobial agents and chemotherapy 20041001 |
| Synthesis and anti-tuberculosis activity of N-aryl-C-nitroazoles. | European journal of medicinal chemistry 20041001 |
| Synthesis and antimycobacterial activity of pyridylmethylsulfanyl and naphthylmethylsulfanyl derivatives of benzazoles, 1, 2, 4-triazole, and pyridine-2-carbothioamide/-2-carbonitrile. | Archiv der Pharmazie 20041001 |
| Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment. | Respiratory medicine 20041001 |
| Dimethyl sulfoxide and ebselen prevent convulsions induced by 5-aminolevulinic acid. | Neurochemical research 20041001 |
| Ebselen protects Ca2+ influx blockage but does not protect glutamate uptake inhibition caused by Hg2+. | Neurochemical research 20041001 |
| Azoles as Suzuki cross-coupling leaving groups: syntheses of 6-arylpurine 2'-deoxynucleosides and nucleosides from 6-(imidazol-1-yl)- and 6-(1,2,4-triazol-4-yl)purine derivatives. | Organic letters 20040916 |
| Nitration and functional loss of voltage-gated K+ channels in rat coronary microvessels exposed to high glucose. | Diabetes 20040901 |
| Nephropathy in Zucker diabetic fat rat is associated with oxidative and nitrosative stress: prevention by chronic therapy with a peroxynitrite scavenger ebselen. | Journal of the American Society of Nephrology : JASN 20040901 |
| The involvement of oxidative stress in bovine herpesvirus type 4-mediated apoptosis. | Frontiers in bioscience : a journal and virtual library 20040901 |
| Protection by flavonoids against the peroxynitrite-mediated oxidation of dihydrorhodamine. | Free radical research 20040901 |
| Interplay among platelet-activating factor, oxidative stress, and group I metabotropic glutamate receptors modulates neuronal survival. | Journal of neuroscience research 20040815 |
| Organochalcogens affect the glutamatergic neurotransmission in human platelets. | Neurochemical research 20040801 |
| Quantitation of lanosterol and its major metabolite FF-MAS in an inhibition assay of CYP51 by azoles with atmospheric pressure photoionization based LC-MS/MS. | Journal of the American Society for Mass Spectrometry 20040801 |
| Voriconazole: therapeutic review of a new azole antifungal. | Expert review of anti-infective therapy 20040801 |
| Comparative assessment of the inhibition of recombinant human CYP19 (aromatase) by azoles used in agriculture and as drugs for humans. | Endocrine research 20040801 |
| Identification and activity of a series of azole-based compounds with lactate dehydrogenase-directed anti-malarial activity. | The Journal of biological chemistry 20040723 |
| Reaction of bromomethylazoles and tosylmethyl isocyanide. A novel heterocyclization method for the synthesis of the core of marine alkaloids variolins and related azolopyrimidines. | The Journal of organic chemistry 20040723 |
| Thiocyanate catalyzes myeloperoxidase-initiated lipid oxidation in LDL. | Free radical biology & medicine 20040715 |
| Transforming growth factor Beta1 induction of tissue inhibitor of metalloproteinases 3 in articular chondrocytes is mediated by reactive oxygen species. | Free radical biology & medicine 20040715 |
| Single-dose ebselen does not afford sustained neuroprotection to rats subjected to severe focal cerebral ischemia. | European journal of pharmacology 20040708 |
| Proliferation of ovarian theca-interstitial cells is modulated by antioxidants and oxidative stress. | Human reproduction (Oxford, England) 20040701 |
| Ebselen decreases oxygen free radical production and iron concentrations in the hearts of chronically iron-overloaded mice. | Biological research for nursing 20040701 |
| Synthesis and fungicidal activity of enantiomerically pure (R)- and (S)-silicon-containing azole fungicides. | Bioorganic & medicinal chemistry 20040701 |
| Substitution of threonine-1351 in the multidrug transporter Cdr1p of Candida albicans results in hypersusceptibility to antifungal agents and threonine-1351 is essential for synergic effects of calcineurin inhibitor FK520. | The Journal of antimicrobial chemotherapy 20040701 |
| The effect of ebselen on adenine nucleotide hydrolysis by platelets from adult rats. | Chemico-biological interactions 20040630 |
| Application of real-time quantitative PCR to molecular analysis of Candida albicans strains exhibiting reduced susceptibility to azoles. | Antimicrobial agents and chemotherapy 20040601 |
| [Oxidative stress in a model for experimental diabetic retinopathy: treatment with antioxidants]. | Archivos de la Sociedad Espanola de Oftalmologia 20040601 |
| Usage of antifungal drugs for therapy of genital Candida infections, purchased as over-the-counter products or by prescription: 2. Factors that may have influenced the marked changes in sales volumes during the 1990s. | Infectious diseases in obstetrics and gynecology 20040601 |
| [Analysis of the mechanism of anti-mycotic activities by azoles potentiated by new erythromycin derivatives]. | The Japanese journal of antibiotics 20040601 |
| Phosphoinositide-dependent kinase 1 and p21-activated protein kinase mediate reactive oxygen species-dependent regulation of platelet-derived growth factor-induced smooth muscle cell migration. | Circulation research 20040514 |
| Optically active antifungal azoles: synthesis and antifungal activity of (2R,3S)-2-(2,4-difluorophenyl)-3-(5-[2-[4-aryl-piperazin-1-yl]-ethyl]-tetrazol-2-yl/1-yl)-1-[1,2,4]-triazol-1-yl-butan-2-ol. | Bioorganic & medicinal chemistry 20040501 |
| Synthesis of [75Se]5-ethoxycarbonyl-4-methyl-1,2,3-selenadiazole. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20040501 |
| Differential effects of the combination of caspofungin and terbinafine against Candida albicans, Candida dubliniensis and Candida kefyr. | International journal of antimicrobial agents 20040501 |
| Chemoenzymatic preparation of nucleoside triphosphates. | Current protocols in nucleic acid chemistry 20040501 |
| Antifungal therapy for keratomycoses. | Expert opinion on pharmacotherapy 20040401 |
| Axial ligand complexes of the Rhodnius nitrophorins: reduction potentials, binding constants, EPR spectra, and structures of the 4-iodopyrazole and imidazole complexes of NP4. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20040301 |
| History of the development of azole derivatives. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040301 |
| Antifungal prophylaxis with azole derivatives. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040301 |
| Clinical significance of breakthrough fungemia caused by azole-resistant Candida tropicalis in patients with hematologic malignancies. | Haematologica 20040301 |
| Newer antifungal agents. | Indian journal of pediatrics 20040301 |
| [Usefulness of the E-test and its assay conditions in the study of the interaction of antifungal agents. A pilot study]. | Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20040301 |
| Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen. | Circulation research 20040220 |
| Ebselen inhibits p38 mitogen-activated protein kinase-mediated endothelial cell death by hydrogen peroxide. | European journal of pharmacology 20040206 |
| Vascular oxidant stress enhances progression and angiogenesis of experimental atheroma. | Circulation 20040203 |
| Additive pro-oxidative effects of methylmercury and ebselen in liver from suckling rat pups. | Toxicology letters 20040202 |
| Drug resistance genes and trailing growth in Candida albicans isolates. | The Journal of antimicrobial chemotherapy 20040201 |
| Ebselen is a dehydroascorbate reductase mimic, facilitating the recycling of ascorbate via mammalian thioredoxin systems. | Antioxidants & redox signaling 20040201 |
| Three-dimensional models of wild-type and mutated forms of cytochrome P450 14alpha-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding. | Antimicrobial agents and chemotherapy 20040201 |
| A new era of antifungal therapy. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040201 |
| Ebselen-mediated protection from single and repeated noise exposure in rat. | The Laryngoscope 20040201 |
| (-)-Epicatechin 3-O-gallate ameliorates the damages related to peroxynitrite production by mechanisms distinct from those of other free radical inhibitors. | The Journal of pharmacy and pharmacology 20040201 |
| Simultaneous analysis of esterase and transferase activities in cytosol proteins from the bovine retina by using microscale non-denaturing two-dimensional electrophoresis. | Biochimica et biophysica acta 20040114 |
| Renal and hepatic ALA-D activity and selected oxidative stress parameters of rats exposed to inorganic mercury and organoselenium compounds. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040101 |
| [Drug discovery in the new era: exploratory research on novel antifungal agents]. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20040101 |
| In vitro evaluation of glutathione peroxidase (GPx)-like activity and antioxidant properties of some Ebselen analogues. | Redox report : communications in free radical research 20040101 |
| [Activity of the azole drugs in vitro against strains of Candida albicans with different codes isolated from the digestive tract in children]. | Wiadomosci parazytologiczne 20040101 |
| A novel series of complexones with bis- or biazole structure as mixed ligands of paramagnetic contrast agents for MRI. | Bioorganic & medicinal chemistry 20031201 |
| Synthesis and biological evaluation of ebselen and its acyclic derivatives. | Chemical & pharmaceutical bulletin 20031201 |
| Management of Candida species infections in critically ill patients. | The Lancet. Infectious diseases 20031201 |
| Multiple mechanisms account for variation in base-line sensitivity to azole fungicides in field isolates of Mycosphaerella graminicola. | Pest management science 20031201 |
| Ebselen inhibits NO-induced apoptosis of differentiated PC12 cells via inhibition of ASK1-p38 MAPK-p53 and JNK signaling and activation of p44/42 MAPK and Bcl-2. | Journal of neurochemistry 20031201 |
| The C2-like beta-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1. | The Journal of biological chemistry 20031031 |
| Ebselen protects against methylmercury-induced inhibition of glutamate uptake by cortical slices from adult mice. | Toxicology letters 20031015 |
| Cobalt-catalyzed arylation of azole heteroarenes via direct C-H bond functionalization. | Organic letters 20031002 |
| Organochalcogens effects on delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro. | Toxicology 20030930 |
| Reactive oxygen species sensitivity of angiotensin II-dependent translation initiation in vascular smooth muscle cells. | The Journal of biological chemistry 20030919 |
| Generation and function of reactive oxygen species in dendritic cells during antigen presentation. | Journal of immunology (Baltimore, Md. : 1950) 20030915 |
| Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae. | The Journal of biological chemistry 20030912 |
| Novel imidazole compounds as a new series of potent, orally active inhibitors of 5-lipoxygenase. | Bioorganic & medicinal chemistry 20030901 |
| Differential modulation of hippocampal chemical-induced injury response by ebselen, pentoxifylline, and TNFalpha-, IL-1alpha-, and IL-6-neutralizing antibodies. | Journal of neuroscience research 20030815 |
| T cell receptor-stimulated generation of hydrogen peroxide inhibits MEK-ERK activation and lck serine phosphorylation. | Free radical biology & medicine 20030815 |
| Kinetic study of azole-bridged dinuclear platinum(II) complexes reacting with a hairpin-stabilized double-stranded oligonucleotide. | Journal of inorganic biochemistry 20030801 |
| Neuroprotective effect of ebselen on rat hippocampal slices submitted to oxygen-glucose deprivation: correlation with immunocontent of inducible nitric oxide synthase. | Neuroscience letters 20030731 |
| Design and biological evaluation of novel antioxidants containing N-t-Butyl-N-hydroxylaminophenyl moieties. | Bioorganic & medicinal chemistry letters 20030721 |
| Ipso- or cine-substitutions of 6-haloimidazo[1,2-a]pyridine derivatives with different azoles depending on the reaction conditions. | The Journal of organic chemistry 20030711 |
| Ebselen attenuates cochlear damage caused by acoustic trauma. | Hearing research 20030701 |
| Evaluation of different calorimetric methods to determine the glass transition temperature and molecular mobility below T(g) for amorphous drugs. | International journal of pharmaceutics 20030618 |
| Potential renal and hepatic toxicity of diphenyl diselenide, diphenyl ditelluride and Ebselen for rats and mice. | Toxicology letters 20030605 |
| Efficacy of caspofungin combined with amphotericin B against azole-resistant Candida albicans. | The Journal of antimicrobial chemotherapy 20030601 |
| A combination chemical and enzymatic approach for the preparation of azole carboxamide nucleoside triphosphate. | The Journal of organic chemistry 20030516 |
| Dual effect of ebselen on mitochondrial permeability transition. | Biochemical pharmacology 20030515 |
| Selective C-arylation of free (NH)-heteroarenes via catalytic C-H bond functionalization. | Journal of the American Chemical Society 20030507 |
| Preparation and pharmacological profile of 7-(alpha-azolylbenzyl)-1H-indoles and indolines as new aromatase inhibitors. | Bioorganic & medicinal chemistry letters 20030505 |
| In vitro and in vivo activity of tea tree oil against azole-susceptible and -resistant human pathogenic yeasts. | The Journal of antimicrobial chemotherapy 20030501 |
| High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501 |
| Induction of cellular necrosis by the glutathione peroxidase mimetic ebselen. | Journal of cellular biochemistry 20030501 |
| Identification of genes differentially expressed in association with reduced azole susceptibility in Saccharomyces cerevisiae. | The Journal of antimicrobial chemotherapy 20030501 |
| Methylmercury increases glutamate release from brain synaptosomes and glutamate uptake by cortical slices from suckling rat pups: modulatory effect of ebselen. | Toxicological sciences : an official journal of the Society of Toxicology 20030501 |
| Influence of heme and heme oxygenase-1 transfection of pulmonary microvascular endothelium on oxidant generation and cGMP. | Experimental biology and medicine (Maywood, N.J.) 20030501 |
| Can the ebselen derivatives catalyze the isomerization of peroxynitrite to nitrate? | Journal of the American Chemical Society 20030402 |
| Effects of anti-ecdysteroid quaternary derivatives of azole analogues of metyrapone on the post-embryonic development of the red cotton bug (Dysdercus cingulatus F). | Pest management science 20030401 |
| Bioconjugation by copper(I)-catalyzed azide-alkyne [3 + 2] cycloaddition. | Journal of the American Chemical Society 20030319 |
| Inhibition by ebselen on nitric oxide mediated relaxations in the rat anococcygeus muscle. | European journal of pharmacology 20030221 |
| Free radical scavengers can differentially modulate the genotoxicity of amsacrine in normal and cancer cells. | Mutation research 20030205 |
| 11beta-Hydroxysteroid dehydrogenase type 1: tissue-specific expression and reductive metabolism of some anti-insect agent azole analogues of metyrapone. | Chemico-biological interactions 20030201 |
| Anti-inflammatory and antinociceptive activity of diphenyl diselenide. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030201 |
| [Antifungal drug]. | Nihon rinsho. Japanese journal of clinical medicine 20030201 |
| Redox catalysts as sensitisers towards oxidative stress. | FEBS letters 20030130 |
| Synthesis and structure-affinity relationship investigations of 5-heteroaryl-substituted analogues of the antipsychotic sertindole. A new class of highly selective alpha(1) adrenoceptor antagonists. | Journal of medicinal chemistry 20030116 |
| Antifungal drug resistance. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030115 |
| Antioxidant ebselen reduces oxidative damage in focal cerebral ischemia. | Free radical biology & medicine 20030101 |
| Phenotyping of Cryptococcus neoformans strains in Bergamo, Italy (1985-2000). | The new microbiologica 20030101 |
| Synthesis and antifungal activity of new 1-halogenobenzyl-3-imidazolylmethylindole derivatives. | European journal of medicinal chemistry 20030101 |
| [Attack point of ergosterol biosynthesis. Drugs and pharmacology]. | Pharmazie in unserer Zeit 20030101 |
| Microbial natural products as a source of antifungals. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20030101 |
| [Azole resistance in Candida spp]. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20030101 |
| Voltage-dependent ebselen and diorganochalcogenides inhibition of 45Ca2+ influx into brain synaptosomes. | Journal of biochemical and molecular toxicology 20030101 |
| [Cytochrome P450 3A4 and Benzodiazepines]. | Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20030101 |
| [New systemic antifungal drugs: mechanisms of action, drug interactions and side effects]. | Mycoses 20030101 |
| [Effect of azole derivatives on lucigenin-dependent microsome chemiluminescence]. | Biomeditsinskaia khimiia 20030101 |
| Synthesis of silicon-containing azole derivatives with magnesium bromide diethyl etherate, and an investigation of their fungicidal activities. | Bioorganic & medicinal chemistry 20021201 |
| [Clinical relevance of mechanisms of antifungal drug resistance in filamentous fungi]. | Enfermedades infecciosas y microbiologia clinica 20021201 |
| Inhibitory effects of 1,3-selenazol-4-one derivatives on mushroom tyrosinase. | Chemical & pharmaceutical bulletin 20021201 |
| Protective effect of ebselen, a seleno-organic compound, against the progression of acute gastric mucosal lesions induced by compound 48/80, a mast cell degranulator, in rats. | Japanese journal of pharmacology 20021201 |
| Deeply invasive candidiasis. | Infectious disease clinics of North America 20021201 |
| [Present status and future prospects of azole antifungal agents in Japan]. | The Japanese journal of antibiotics 20021201 |
| Tin-free radical sequences under acidic conditions. Convergent access to azole-containing structures. | Organic letters 20021128 |
| Synthesis of N-cycloalkenylazoles. | The Journal of organic chemistry 20021115 |
| Synthetic applications of azolium ylides to a traceless solid-phase synthesis of 2-substituted azoles. | Organic letters 20021114 |
| Histone deacetylase inhibitors enhance Candida albicans sensitivity to azoles and related antifungals: correlation with reduction in CDR and ERG upregulation. | Antimicrobial agents and chemotherapy 20021101 |
| Clinical relevance of mechanisms of antifungal drug resistance in yeasts. | Enfermedades infecciosas y microbiologia clinica 20021101 |
| A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase. | The Journal of biological chemistry 20021018 |
| Has antifungal susceptibility testing come of age? | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021015 |
| Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals. | Bioorganic & medicinal chemistry letters 20021007 |
| Antifungal activity in Saccharomyces cerevisiae is modulated by calcium signalling. | Molecular microbiology 20021001 |
| Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes. | Microbiology (Reading, England) 20021001 |
| The neuroprotectant ebselen inhibits oxidative DNA damage induced by dopamine in the presence of copper ions. | Neuroscience letters 20020913 |
| Intrahippocampal infusion of ebselen impairs retention of an inhibitory avoidance task in rats. | European journal of pharmacology 20020913 |
| Treatment of azole-resistant oropharyngeal candidiasis with topical amphotericin B. | The Annals of pharmacotherapy 20020901 |
| Antifungal drug resistance to azoles and polyenes. | The Lancet. Infectious diseases 20020901 |
| Role of oxygen and nitrogen species in experimental uveitis: anti-inflammatory activity of the synthetic antioxidant ebselen. | Free radical biology & medicine 20020901 |
| Tolerability, safety and efficacy of conventional amphotericin B administered by 24-hour infusion to lung transplant recipients. | Swiss medical weekly 20020810 |
| Ebselen attenuates oxidative stress-induced apoptosis via the inhibition of the c-Jun N-terminal kinase and activator protein-1 signalling pathway in PC12 cells. | British journal of pharmacology 20020801 |
| Effects of C-nitropyrazoles and C-nitroazoles on ocular blood flow and retinal function recovery after ischemic insult. | Acta pharmacologica Sinica 20020801 |
| Ebselen protects against the reduction in levels of drug-metabolizing enzymes in livers of rats with deoxycholic acid-induced liver injury. | Pharmacology & toxicology 20020801 |
| Unsymmetrical 1,1'-disubstituted ferrocenes: synthesis of Co(ii), Cu(ii), Ni(ii) and Zn(ii) chelates of ferrocenyl -1-thiadiazolo-1'-tetrazole, -1-thiadiazolo-1'-triazole and -1-tetrazolo-1'-triazole with antimicrobial properties. | Journal of enzyme inhibition and medicinal chemistry 20020801 |
| Effects of angiotensin II type 1 receptor antagonist, YM358, on cardiac hypertrophy and dysfunction after myocardial infarction in rats. | Biological & pharmaceutical bulletin 20020701 |
| Effect of Micafungin (FK463) on Candida albicans adherence to epithelial cells. | Chemotherapy 20020701 |
| Effects of antioxidants on surfactant peroxidation by stimulated human polymorphonuclear leukocytes. | Free radical research 20020701 |
| Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells. | Circulation research 20020628 |
| In vitro activity of caspofungin (MK-0991) against Candida albicans clinical isolates displaying different mechanisms of azole resistance. | Journal of clinical microbiology 20020601 |
| Divergent pathways account for two distinct effects of amyloid beta peptides on exocytosis and Ca(2+) currents: involvement of ROS and NF-kappaB. | Journal of neurochemistry 20020601 |
| Nitric oxide mediates apoptosis induction selectively in transformed fibroblasts compared to nontransformed fibroblasts. | Carcinogenesis 20020601 |
| The effects of ebselen on cisplatin and diethyldithiocarbamate (DDC) cytotoxicity in rat hippocampal astrocytes. | Toxicology letters 20020528 |
| Comparative toxicological assessment of a water-soluble azole administered both orally and by intravenous continuous infusion in cynomolgus monkeys. | The Journal of toxicological sciences 20020501 |
| Homozygosity at the Candida albicans MTL locus associated with azole resistance. | Microbiology (Reading, England) 20020401 |
| Exposure to ebselen changes glutamate uptake and release by rat brain synaptosomes. | Neurochemical research 20020401 |
| Antioxidant properties of new chalcogenides against lipid peroxidation in rat brain. | Neurochemical research 20020401 |
| Do azoles and chloroquine share similar mechanisms of antimalarial action? | Trends in parasitology 20020401 |
| Diagnosis and treatment of invasive pulmonary aspergillosis in neutropenic patients. | The European respiratory journal 20020401 |
| Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway. | Science (New York, N.Y.) 20020329 |
| Ammonium chloride-promoted four-component synthesis of pyrrolo[3,4-b]pyridin-5-one. | Journal of the American Chemical Society 20020320 |
| Ebselen has dehydroascorbate reductase and thioltransferase-like activities. | Biochemical and biophysical research communications 20020301 |
| Ebselen suppresses late airway responses and airway inflammation in guinea pigs. | Free radical biology & medicine 20020301 |
| Synthesis, characterisation and biological activity of novel 4-thiazolidinones, 1,3,4-oxadiazoles and some related compounds. | European journal of medicinal chemistry 20020301 |
| Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis. | Journal of mass spectrometry : JMS 20020301 |
| Ebselen blocks the quinolinic acid-induced production of thiobarbituric acid reactive species but does not prevent the behavioral alterations produced by intra-striatal quinolinic acid administration in the rat. | Neuroscience letters 20020201 |
| Molecular basis of resistance to azole antifungals. | Trends in molecular medicine 20020201 |
| Resistance of Candida species to antifungal agents: molecular mechanisms and clinical consequences. | The Lancet. Infectious diseases 20020201 |
| Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis. | The Journal of biological chemistry 20020125 |
| Carbonic anhydrase activators: design of high affinity isozymes I, II, and IV activators, incorporating tri-/tetrasubstituted-pyridinium-azole moieties. | Journal of medicinal chemistry 20020117 |
| Formation of active oxygen species and lipid peroxidation induced by hypochlorite. | Archives of biochemistry and biophysics 20020115 |
| Analytical and semipreparative enantiomeric separation of azole antifungal agents by high-performance liquid chromatography on polysaccharide-based chiral stationary phases. Application to in vitro biological studies. | Journal of chromatography. A 20020104 |
| Novel 1-hydroxyazole bioisosteres of glutamic acid. Synthesis, protolytic properties, and pharmacology. | Journal of medicinal chemistry 20020103 |
| The impact of polyene, azole, and DNA analogue antimycotics on the cell surface hydrophobicity of Candida albicans and Candida tropicalis in HIV infection. | Mycopathologia 20020101 |
| Detection of human P-glycoprotein-like molecule in azole-resistant Candida albicans from HIV+ patients. | Microbial drug resistance (Larchmont, N.Y.) 20020101 |
| Action of peroxidases on protein hydroperoxides. | Redox report : communications in free radical research 20020101 |
| Study of the thermal behavior of azidohetarenes with differential scanning calorimetry. | Journal of biochemical and biophysical methods 20020101 |
| Overview: fungal infections in the transplant patient. | Transplant infectious disease : an official journal of the Transplantation Society 20020101 |
| Fungal infection in liver transplantation. | Transplant infectious disease : an official journal of the Transplantation Society 20020101 |
| Synthesis of some new azoles and azines and their condensed derivatives. | Bollettino chimico farmaceutico 20020101 |
| Impact of strobilurins on physiology and yield formation of wheat. | Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) 20020101 |
| A novel dicyclodextrinyl ditelluride compound with antioxidant activity. | FEBS letters 20011102 |
| Oxidative and nitrosative stress in acute renal ischemia. | American journal of physiology. Renal physiology 20011101 |
| Extrusion of fluorescein diacetate by multidrug-resistant Candida albicans. | Mycoses 20011101 |
| Anti-oxidant ebselen causes the resolution of experimentally induced hepatic fibrosis in rats. | Journal of gastroenterology and hepatology 20011101 |
| Update on antifungal agents. | The Pediatric infectious disease journal 20011001 |
| Cryptococcosis in human immunodeficiency virus-negative patients in the era of effective azole therapy. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010901 |
| Prevalence of vaginal colonization by drug-resistant Candida species in college-age women with previous exposure to over-the-counter azole antifungals. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010901 |
| Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia. | Stroke 20010901 |
| Optically active antifungal azoles. XII. Synthesis and antifungal activity of the water-soluble prodrugs of 1-[(1R,2R)-2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-3-[4-(1H-1-tetrazolyl)phenyl]-2-imidazolidinone. | Chemical & pharmaceutical bulletin 20010901 |
| Carbon disulfide promoted reactions of 2-chloro-4,5-dihydro-imidazole with some N-nucleophiles. | Chemical & pharmaceutical bulletin 20010901 |
| The neuroprotective agent ebselen modifies NMDA receptor function via the redox modulatory site. | Journal of neurochemistry 20010901 |
| The KEX2 gene of Candida glabrata is required for cell surface integrity. | Molecular microbiology 20010901 |
| Potential application of plant lipid transfer proteins for drug delivery. | Biochemical pharmacology 20010901 |
| Synthesis and biological evaluation of azole derivatives, analogues of bifonazole, with a phenylisoxazolyl or phenylpyrimidinyl moiety. | Farmaco (Societa chimica italiana : 1989) 20010901 |
| Azole-antifungal binding to a novel cytochrome P450 from Mycobacterium tuberculosis: implications for treatment of tuberculosis. | Biochemical pharmacology 20010615 |
| Mitochondrial membrane potential in density-separated trout erythrocytes exposed to oxidative stress in vitro. | Biochimica et biophysica acta 20010601 |
| Comparisons of pKa and log P values of some carboxylic and phosphonic acids: synthesis and measurement. | AAPS pharmSci 20010601 |
| Therapy for fungal infections in leukemia. | Current oncology reports 20010501 |
| The amino acid residues affecting the activity and azole susceptibility of rat CYP51 (sterol 14-demethylase P450). | Journal of biochemistry 20010501 |
| OxLDL induces macrophage gamma-GCS-HS protein expression: a role for oxLDL-associated lipid hydroperoxide in GSH synthesis. | Journal of lipid research 20010501 |
| An old activity in the cytochrome P450 superfamily (CYP51) and a new story of drugs and resistance. | Biochemical Society transactions 20010501 |
| Comparison of the angiotensin II type 1-receptor antagonist YM358 and the angiotensin-converting enzyme inhibitor enalapril in rats with cardiac volume overload. | Japanese journal of pharmacology 20010501 |
| Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells. | Arteriosclerosis, thrombosis, and vascular biology 20010401 |
| Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases. | Japanese journal of cancer research : Gann 20010401 |
| Preventive effect of ebselen on acute gastric mucosal lesion development in rats treated with compound 48/80. | European journal of pharmacology 20010302 |
| The selenoorganic compound ebselen suppresses liver injury induced by Propionibacterium acnes and lipopolysaccharide in rats. | International journal of molecular medicine 20010301 |
| Itraconazole-enhanced vincristine neurotoxicity in a child with acute lymphoblastic leukemia. | Pediatric hematology and oncology 20010301 |
| [The activity of systemic antimycotic drug combinations]. | Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20010301 |
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| Ebselen prevents excitotoxicity provoked by glutamate in rat cerebellar granule neurons. | Neuroscience letters 20010223 |
| Ebselen prevents early alcohol-induced liver injury in rats. | Free radical biology & medicine 20010215 |
| Extracts from 'Clinical evidence': Athlete's foot and fungally infected toenails. | BMJ (Clinical research ed.) 20010203 |
| Effect of ketoconazole, itraconazole and fluconazole on the gastrointestinal colonization of mice by Candida albicans. | Journal of chemotherapy (Florence, Italy) 20010201 |
| Antifungal and immunomodulating activities of 1,4-benzothiazine azole derivatives: review. | Journal of chemotherapy (Florence, Italy) 20010201 |
| The effects of thiol compounds and ebselen on nitric oxide activity in rat aortic vascular responses. | Journal of autonomic pharmacology 20010201 |
| [Metabolic interactions with statins]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20010120 |
| Reactive oxygen species and caspase activation mediate silica-induced apoptosis in alveolar macrophages. | American journal of physiology. Lung cellular and molecular physiology 20010101 |
| The combination of oral amphotericin B with azoles prevents the emergence of resistant Candida species in neutropenic patients. | British journal of haematology 20010101 |
| Clinical applicability of antifungal susceptibility testing on non-Candida albicans species in hospitalized patients. | Diagnostic microbiology and infectious disease 20010101 |
| Selective inhibition of vitamin D hydroxylases in human keratinocytes. | Steroids 20010101 |
| Antiviral activity of the products of cyclization of dimethyl 2-[(1-arylamino-1-arylmethylidene)hydrazono]succinate. | European journal of medicinal chemistry 20010101 |
| In vitro susceptibility of 137 Candida sp. isolates from HIV positive patients to several antifungal drugs. | Mycopathologia 20010101 |
| Treatment of systemic fungal infections in older patients: achieving optimal outcomes. | Drugs & aging 20010101 |
| Oral colonization by Candida spp. among AIDS household contacts. | Mycoses 20010101 |
| Inhibition of ebselen on aflatoxin B(1)-induced hepatocarcinogenesis in Fischer 344 rats. | Carcinogenesis 20001201 |
| Optically active antifungal azoles. X. Synthesis and antifungal activity of N. | Chemical & pharmaceutical bulletin 20001201 |
| Bactericidal and inhibitory effects of azole antifungal compounds on Mycobacterium smegmatis. | FEMS microbiology letters 20001115 |
| Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitors. | Antimicrobial agents and chemotherapy 20001001 |
| A new class of antifungal agents. Synthesis and antimycotic activity of disubstituted N-azolylamines. | Archiv der Pharmazie 20000901 |
| Efficacy of FK463, a (1,3)-beta-D-glucan synthase inhibitor, in disseminated azole-resistant candida albicans infection in mice. | Antimicrobial agents and chemotherapy 20000601 |
| In vitro synergism between nyasol, an active compound isolated from Anemarrhena asphodeloides, and azole agents against Candida albicans. | Planta medica 20000601 |
| Current and emerging azole antifungal agents. | Clinical microbiology reviews 19990101 |
| Azole derivatives of 1,4-benzothiazine as antifungal agents. | Bioorganic & medicinal chemistry 19980101 |
| Prolongation of the QT interval related to cisapride-diltiazem interaction. | Pharmacotherapy 19980101 |
| Antifungal, antibacterial, antiviral and cytotoxic activity of novel thio- and seleno-azoles. | Pharmacological research 19970901 |
| In vitro activity of a new pneumocandin antifungal, L-743,872, against azole-susceptible and -resistant Candida species. | Antimicrobial agents and chemotherapy 19970701 |
| In vitro activity of a new pneumocandin antifungal agent, L-733,560 against azole-susceptible and -resistant Candida and Torulopsis species. | Antimicrobial agents and chemotherapy 19951201 |
| Molecular actions of ebselen--an antiinflammatory antioxidant. | General pharmacology 19951001 |
| Synthesis and antifungal activity of new azole derivatives containing an N-acylmorpholine ring. | Journal of medicinal chemistry 19950929 |
| Optically active antifungal azoles. IV. Synthesis and antifungal activity of (2R,3R)-3-azolyl-2-(substituted phenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanols. | Chemical & pharmaceutical bulletin 19950301 |
| Optically active antifungal azoles. V. Synthesis and antifungal activity of stereoisomers of 3-azolyl-2-(substituted phenyl)-1-(1H-1,2,4-triazol-1-yl)-2- butanols. | Chemical & pharmaceutical bulletin 19950301 |
| Interaction of ebselen with glutathione S-transferase and papain in vitro. | Biochemical pharmacology 19940315 |
| PZ-51 (Ebselen) in vivo protection against adriamycin-induced mouse cardiac and hepatic lipid peroxidation and toxicity. | Biochemical pharmacology 19920818 |
| Plant sterol biosynthesis: novel potent and selective inhibitors of cytochrome P450-dependent obtusifoliol 14 alpha-methyl demethylase. | Archives of biochemistry and biophysics 19920815 |
| In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin. | Antimicrobial agents and chemotherapy 19920801 |
| Positive interaction of nikkomycins and azoles against Candida albicans in vitro and in vivo. | Antimicrobial agents and chemotherapy 19920601 |
| Saperconazole: in vitro and in vivo anticandidal activity. | Chemotherapy 19920101 |
| Comparison of SCH 39304 and its isomers, RR 42427 and SS 42426, for treatment of murine cryptococcal and coccidioidal meningitis. | Antimicrobial agents and chemotherapy 19920101 |
| Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis. | Pancreas 19910501 |
| Hypotensive action of DuP 753, an angiotensin II antagonist, in spontaneously hypertensive rats. Nonpeptide angiotensin II receptor antagonists: X. | Hypertension (Dallas, Tex. : 1979) 19900501 |
| Increased external carotid artery blood flow in headache patients induced by cilostazol. Preliminary communication. | Arzneimittel-Forschung 19900501 |
| Two distinct angiotensin II receptor binding sites in rat adrenal revealed by new selective nonpeptide ligands. | Molecular pharmacology 19900301 |
| Overview of medically important antifungal azole derivatives. | Clinical microbiology reviews 19880401 |
| Synthesis and oral antifungal activity of novel azolylpropanolones and related compounds. | Journal of medicinal chemistry 19870601 |
| In vitro activity of ME1401, a new antifungal agent. | Antimicrobial agents and chemotherapy 19861101 |
| Synthesis of tetrazole ribonucleosides and their evaluation as antiviral agents. 2. 5-Amino-1-(beta-D-ribofuranosyl)-1H-tetrazole and 5-amino-2-(beta-D-ribofuranosyl)-2H-tetrazole. | Journal of medicinal chemistry 19760801 |
| Synthesis of tetrazole ribonucleosides and their evaluation as antiviral agents. | Journal of medicinal chemistry 19760201 |
| Urinary calculi with methazolamide therapy. | Documenta ophthalmologica. Advances in ophthalmology 19730221 |