AS601245
| Title | Journal |
|---|---|
| The MAPK pathway signals telomerase modulation in response to isothiocyanate-induced DNA damage of human liver cancer cells. | PloS one 20130101 |
| Rosiglitazone and AS601245 decrease cell adhesion and migration through modulation of specific gene expression in human colon cancer cells. | PloS one 20120101 |
| A phospholipase A₂ isolated from Lachesis muta snake venom increases the survival of retinal ganglion cells in vitro. | Toxicon : official journal of the International Society on Toxinology 20110315 |
| Preantral follicle growth is regulated by c-Jun-N-terminal kinase (JNK) pathway. | Reproductive sciences (Thousand Oaks, Calif.) 20110301 |
| High dose of pyridoxine induces IGFBP-3 mRNA expression in MCF-7 cells and its induction is inhibited by the p53-specific inhibitor pifithrin-α. | Journal of nutritional science and vitaminology 20110101 |
| Basal c-Jun NH2-terminal protein kinase activity is essential for survival and proliferation of T-cell acute lymphoblastic leukemia cells. | Molecular cancer therapeutics 20091201 |
| Increased operant responding for ethanol in male C57BL/6J mice: specific regulation by the ERK1/2, but not JNK, MAP kinase pathway. | Psychopharmacology 20090501 |
| Differential roles of p38-MAPK and JNKs in mediating early protection or apoptosis in the hyperthermic perfused amphibian heart. | The Journal of experimental biology 20080801 |
| AS601245, a c-Jun NH2-terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils. | British journal of pharmacology 20080101 |
| Pharmacologic inhibitors of extracellular signal-regulated kinase (ERKs) and c-Jun NH(2)-terminal kinase (JNK) decrease glutathione content and sensitize human promonocytic leukemia cells to arsenic trioxide-induced apoptosis. | Journal of cellular physiology 20061201 |
| Agents targeting c-Jun N-terminal kinase pathway as potential neuroprotectants. | Expert opinion on investigational drugs 20051101 |
| Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase. | Journal of medicinal chemistry 20050714 |
| Control of death receptor and mitochondrial-dependent apoptosis by c-Jun N-terminal kinase in hippocampal CA1 neurones following global transient ischaemia. | Journal of neurochemistry 20050301 |
| AS601245 (1,3-benzothiazol-2-yl (2-[[2-(3-pyridinyl) ethyl] amino]-4 pyrimidinyl) acetonitrile): a c-Jun NH2-terminal protein kinase inhibitor with neuroprotective properties. | The Journal of pharmacology and experimental therapeutics 20040701 |
| Inhibition of c-Jun N-terminal kinase decreases cardiomyocyte apoptosis and infarct size after myocardial ischemia and reperfusion in anaesthetized rats. | British journal of pharmacology 20040701 |