(2R,3S,4R,5R)-2-(hydroxymethyl)-5-[6-(methylsulfanyl)-9H-purin-9-yl]oxolane-3,4-diol
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Simultaneous quantification of eleven thiopurine nucleotides by liquid chromatography-tandem mass spectrometry. | Analytical chemistry 20120207 |
Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing. | Biochemistry 20110222 |
A thiopurine drug inhibits West Nile virus production in cell culture, but not in mice. | PloS one 20110101 |
Crystallographic and docking studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry 20100701 |
Health-related quality of life of youth with inflammatory bowel disease: a comparison with published data using the PedsQL 4.0 generic core scales. | Inflammatory bowel diseases 20100601 |
Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. | Bioorganic & medicinal chemistry 20080401 |
Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner. | The Journal of general virology 20080401 |
Synthesis and biological evaluation of nucleoside analogues having 6-chloropurine as anti-SARS-CoV agents. | Bioorganic & medicinal chemistry letters 20070501 |
Identification of an in vivo inhibitor of Bacillus anthracis spore germination. | The Journal of biological chemistry 20070420 |
[Monitoring of thiopurine methyltransferase and thiopurine metabolites to optimize azathioprine therapy in inflammatory bowel disease]. | Gastroenterologia y hepatologia 20061101 |
Molecular mechanisms underlying the enhanced sensitivity of thiopurine-resistant T-lymphoblastic cell lines to methyl mercaptopurineriboside. | Biochemical pharmacology 20060928 |
A prospective, open-label trial of 6-thioguanine in patients with ulcerative or indeterminate colitis. | Scandinavian journal of gastroenterology 20051001 |
Improved synthesis of beta-D-6-methylpurine riboside and antitumor effects of the beta-D- and alpha-D-anomers. | Molecules (Basel, Switzerland) 20050831 |
Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins. | The Journal of biological chemistry 20050311 |
Synthesis of oligoribonucleotides containing N6-alkyladenosine and 2-methylthio-N6-alkyladenosine. | Current protocols in nucleic acid chemistry 20040901 |
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function. | The Journal of biological chemistry 20040430 |
Status of methylthioadenosine phosphorylase and its impact on cellular response to L-alanosine and methylmercaptopurine riboside in human soft tissue sarcoma cells. | Oncology research 20040101 |
Monitoring of AZA/6-MP treatment in children with IBD is necessary. | Inflammatory bowel diseases 20031101 |
Monitoring of azathioprine/6-mercaptopurine treatment in children with IBD is not necessary. | Inflammatory bowel diseases 20031101 |
Thiopurine metabolism and identification of the thiopurine metabolites transported by MRP4 and MRP5 overexpressed in human embryonic kidney cells. | Molecular pharmacology 20021201 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. | Journal of medicinal chemistry 20010719 |
Synthesis and antiviral activity of carbocyclic analogues of 2'-deoxyribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines. | Journal of medicinal chemistry 19841101 |
Synthesis and antiviral activity of certain carbamoylpyrrolopyrimidine and pyrazolopyrimidine nucleosides. | Journal of medicinal chemistry 19821101 |
Purine analogs as potential anticytomegalovirus agents. | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 19690901 |