(S)-2-Amino-2-((S)-3-chloro-4,5-dihydroisoxazol-5-yl)acetic acid
| Title | Journal |
|---|---|
| An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery. | Disease models & mechanisms 20130301 |
| Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. | Bioorganic & medicinal chemistry 20121115 |
| Luminal transport of thiol S-conjugates of methylmercury in isolated perfused rabbit renal proximal tubules. | Toxicology letters 20120903 |
| Glutathione and Bcl-2 targeting facilitates elimination by chemoradiotherapy of human A375 melanoma xenografts overexpressing bcl-xl, bcl-2, and mcl-1. | Journal of translational medicine 20120101 |
| Gastric epithelial cell death caused by Helicobacter suis and Helicobacter pylori γ-glutamyl transpeptidase is mainly glutathione degradation-dependent. | Cellular microbiology 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| Glutathione is a physiologic reservoir of neuronal glutamate. | Biochemical and biophysical research communications 20110617 |
| Ammonia channeling in Plasmodium falciparum GMP synthetase: investigation by NMR spectroscopy and biochemical assays. | Biochemistry 20110426 |
| Glutamate reduces experimental intestinal hyperpermeability and facilitates glutamine support of gut integrity. | World journal of gastroenterology 20110328 |
| A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
| The biological targets of acivicin inspired 3-chloro- and 3-bromodihydroisoxazole scaffolds. | Chemical communications (Cambridge, England) 20101128 |
| The control of S-thiolation by cysteine via gamma-glutamyltranspeptidase and thiol exchanges in erythrocytes and plasma of diamide-treated rats. | Toxicology and applied pharmacology 20100201 |
| Extracellular redox modulation by regulatory T cells. | Nature chemical biology 20091001 |
| Role of gamma-glutamyl transpeptidase in redox regulation of K+ channel remodeling in postmyocardial infarction rat hearts. | American journal of physiology. Cell physiology 20090801 |
| Crystal structure of acivicin-inhibited gamma-glutamyltranspeptidase reveals critical roles for its C-terminus in autoprocessing and catalysis. | Biochemistry 20090324 |
| Crystal structures of Escherichia coli gamma-glutamyltranspeptidase in complex with azaserine and acivicin: novel mechanistic implication for inhibition by glutamine antagonists. | Journal of molecular biology 20080704 |
| On the role of tyrosine and peripheral metabolism in 3,4-methylenedioxymethamphetamine-induced serotonin neurotoxicity in rats. | Neuropharmacology 20080401 |
| Toluene-induced hearing loss in acivicin-treated rats. | Neurotoxicology and teratology 20080101 |
| Acivicin with glutaminase regulates proliferation and invasion of human MCF-7 and OAW-42 cells--an in vitro study. | Indian journal of experimental biology 20080101 |
| Towards a molecular genetic system for the pathogenic fungus Paracoccidioides brasiliensis. | Fungal genetics and biology : FG & B 20071201 |
| Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus. | Chemistry & biology 20071001 |
| gamma-Glutamyl transpeptidase GGT4 initiates vacuolar degradation of glutathione S-conjugates in Arabidopsis. | FEBS letters 20070710 |
| The effect of modulation of gamma-glutamyl transpeptidase and nitric oxide synthase activity on GSH homeostasis in HepG2 cells. | Fundamental & clinical pharmacology 20070201 |
| Function of phytochelatin synthase in catabolism of glutathione-conjugates. | The Plant journal : for cell and molecular biology 20070201 |
| The effect of different antioxidants on glutathione turnover in human cell lines and their interaction with hydrogen peroxide. | Chemico-biological interactions 20061107 |
| Subcellular localization and possible functions of gamma-glutamyltransferase in the radish (Raphanus sativus L.) plant. | Bioscience, biotechnology, and biochemistry 20060701 |
| Evidence of a new dechlorinated ochratoxin A derivative formed in opossum kidney cell cultures after pretreatment by modulators of glutathione pathways: correlation with DNA-adduct formation. | Molecular nutrition & food research 20060501 |
| Thyroid hormone stimulates gamma-glutamyl transpeptidase in the developing rat cerebra and in astroglial cultures. | Journal of neuroscience research 20051215 |
| Glutathione turnover in human cell lines in the presence of agents with glutathione influencing potential with and without acivicin inhibition of gamma-glutamyltranspeptidase. | Biochimica et biophysica acta 20051030 |
| On the two components of pyridoxal 5'-phosphate synthase from Bacillus subtilis. | The Journal of biological chemistry 20050916 |
| Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. | Journal of pharmaceutical sciences 20050701 |
| Effect of glutamine analogue-acivicin on tumor induced angiogenesis in Ehrlich ascites carcinoma. | Indian journal of experimental biology 20050501 |
| Role of glutathione in reduction of arsenate and of gamma-glutamyltranspeptidase in disposition of arsenite in rats. | Toxicology 20050201 |
| Contribution of acetaminophen-cysteine to acetaminophen nephrotoxicity II. Possible involvement of the gamma-glutamyl cycle. | Toxicology and applied pharmacology 20050115 |
| Nonprotein thiols and disulfides in rat epididymal spermatozoa and epididymal fluid: role of gamma-glutamyl-transpeptidase in sperm maturation. | Journal of andrology 20050101 |
| Increased extracellular glutamate evoked by 1-methyl-4-phenylpyridinium [MPP(+)] in the rat striatum is not essential for dopaminergic neurotoxicity and is not derived from released glutathione. | Neurotoxicity research 20050101 |
| High glutathione turnover in human cell lines revealed by acivicin inhibition of gamma-glutamyltranspeptidase and the effects of thiol-reactive metals during acivicin inhibition. | Clinica chimica acta; international journal of clinical chemistry 20041101 |
| Inhibition of gamma-glutamyl transpeptidase activity decreases intracellular cysteine levels in cervical carcinoma. | Cancer chemotherapy and pharmacology 20040701 |
| Concentration-dependent effects of endogenous S-nitrosoglutathione on gene regulation by specificity proteins Sp3 and Sp1. | The Biochemical journal 20040515 |
| Acivicin-induced alterations in renal and hepatic glutathione concentrations and in gamma-glutamyltransferase activities. | Biochemical pharmacology 20040401 |
| Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor. | The Journal of biological chemistry 20040213 |
| Gamma-glutamyl transpeptidase inhibition suppresses milk protein synthesis in isolated ovine mammary cells. | Journal of dairy science 20040201 |
| Inhibitors of CTP biosynthesis potentiate the anti-human immunodeficiency virus type 1 activity of 3TC in activated peripheral blood mononuclear cells. | Antiviral research 20040101 |
| Bile secretory function after warm hepatic ischemia-reperfusion injury in the rat. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20031101 |
| Acivicin induce filamentous growth of Saccharomyces cerevisiae. | Bioscience, biotechnology, and biochemistry 20031001 |
| S-nitrosylation signaling in cell biology. | Molecular interventions 20030801 |
| Design, synthesis, and evaluation of gluten peptide analogs as selective inhibitors of human tissue transglutaminase. | Chemistry & biology 20030301 |
| Organisation and sequence determination of glutamine-dependent carbamoyl phosphate synthetase II in Toxoplasma gondii. | International journal for parasitology 20030101 |
| Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase. | Pigment cell research 20021201 |
| Glutathione secretion into rat milk and its subsequent gamma-glutamyltranspeptidase-mediated catabolism. | Biology of the neonate 20020801 |
| Cysteinyl leukotrienes induce IL-4 release from cord blood-derived human eosinophils. | The Journal of allergy and clinical immunology 20020601 |
| Role of gamma-glutamyltranspeptidase on the response of poorly and moderately differentiated rhabdomyosarcoma cell lines to buthionine sulfoximine-induced inhibition of glutathione synthesis. | Anti-cancer drugs 20020301 |
| Gamma-glutamyl transpeptidase activity mediates NF-kappaB activation through lipid peroxidation in human leukemia U937 cells. | Molecular and cellular biochemistry 20020301 |
| Inactivation of the amidotransferase activity of carbamoyl phosphate synthetase by the antibiotic acivicin. | The Journal of biological chemistry 20020208 |
| Inhibition of gamma-glutamyl transpeptidase or cysteine S-conjugate beta-lyase activity blocks the nephrotoxicity of cisplatin in mice. | The Journal of pharmacology and experimental therapeutics 20020101 |
| gamma-Glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver. | Hepatology (Baltimore, Md.) 20020101 |
| gamma-Glutamyltranspeptidase and gamma-glutamyl peptide ligases: fluorophosphonate and phosphonodifluoromethyl ketone analogs as probes of tetrahedral transition state and gamma-glutamyl-phosphate intermediate. | Methods in enzymology 20020101 |
| Reanalysis of the involvement of gamma-glutamyl transpeptidase in the cell activation process. | FEBS letters 20011116 |
| S-nitrosothiols signal the ventilatory response to hypoxia. | Nature 20010913 |
| Acivicin induces apoptosis independently of gamma-glutamyltranspeptidase activity. | Biochemical and biophysical research communications 20010803 |
| Serotonergic neurotoxicity of 3,4-(+/-)-methylenedioxyamphetamine and 3,4-(+/-)-methylendioxymethamphetamine (ecstasy) is potentiated by inhibition of gamma-glutamyl transpeptidase. | Chemical research in toxicology 20010701 |
| S-nitrosoglutathione increases cystic fibrosis transmembrane regulator maturation. | Biochemical and biophysical research communications 20010601 |
| Glutathione deficiency intensifies ischaemia-reperfusion induced cardiac dysfunction and oxidative stress. | Acta physiologica Scandinavica 20010501 |
| [Anti-cancer therapy with amino acid imbalance]. | Nihon rinsho. Japanese journal of clinical medicine 20010501 |
| A bioreversible prodrug approach designed to shift mechanism of brain uptake for amino-acid-containing anticancer agents. | Journal of neurochemistry 20010201 |
| Mechanism for acivicin inactivation of triad glutamine amidotransferases. | Biochemistry 20010130 |
| Isolated liver perfusion permits administration of high doses of chemotherapeutic agents. Comparison with hepatic artery infusion. | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20010101 |
| Role of the renal cysteine conjugate beta-lyase pathway in inhaled compound A nephrotoxicity in rats. | Anesthesiology 19980601 |
| Cytotoxicity and cell-proliferation induced by the nephrocarcinogen hydroquinone and its nephrotoxic metabolite 2,3,5-(tris-glutathion-S-yl)hydroquinone. | Carcinogenesis 19971201 |
| Quantitative differences in the production and toxicity of CF2=BrCl versus CH2F-O-C(=CF2)(CF3) (compound A): the safety of halothane does not indicate the safety of sevoflurane. | Anesthesia and analgesia 19971101 |
| Leukotrienes and alpha-naphthylisothiocyanate-induced liver injury. | Toxicology 19950626 |
| Nephrotoxicity of 4-amino-3-S-glutathionylphenol and its modulation by metabolism or transport inhibitors. | Archives of toxicology 19940101 |
| Studies on the effects of L(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) on 4-aminophenol-induced nephrotoxicity in the Fischer 344 rat. | Archives of toxicology 19930101 |
| Inhibition of gamma-glutamyl transpeptidase potentiates the nephrotoxicity of glutathione-conjugated chlorohydroquinones. | Toxicology and applied pharmacology 19910801 |
| Endogenously formed leukotriene C4 activates LTC4 receptors in guinea pig tracheal strips. | European journal of pharmacology 19910326 |
| In vivo nephrotoxic action of an isomeric mixture of S-(1-phenyl-2-hydroxyethyl)glutathione and S-(2-phenyl-2-hydroxyethyl)glutathione in Fischer-344 rats. | Toxicology 19910325 |
| Sequential oxidation and glutathione addition to 1,4-benzoquinone: correlation of toxicity with increased glutathione substitution. | Molecular pharmacology 19881201 |
| Possible role of hepatic glutathione in transport of methylmercury into mouse kidney. | Biochemical pharmacology 19880115 |
| Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity. | Biochemical pharmacology 19860115 |