2-Chloro-5-nitro-N-4-pyridinylbenzamide
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Bisphenol A induces Pomc gene expression through neuroinflammatory and PPARγ nuclear receptor-mediated mechanisms in POMC-expressing hypothalamic neuronal models. | Molecular and cellular endocrinology 20180824 |
Regulation of the placental BCRP transporter by PPAR gamma. | Journal of biochemical and molecular toxicology 20170501 |
Rosmarinic Acid Protects against Inflammation and Cardiomyocyte Apoptosis during Myocardial Ischemia/Reperfusion Injury by Activating Peroxisome Proliferator-Activated Receptor Gamma. | Frontiers in pharmacology 20170101 |
Municipal wastewater affects adipose deposition in male mice and increases 3T3-L1 cell differentiation. | Toxicology and applied pharmacology 20160415 |
CDK5-induced p-PPARγ(Ser 112) downregulates GFAP via PPREs in developing rat brain: effect of metal mixture and troglitazone in astrocytes. | Cell death & disease 20140101 |
Peroxisome proliferator-activated receptor delta antagonists inhibit hepatitis C virus RNA replication. | Bioorganic & medicinal chemistry letters 20130901 |
Evidence for a luteotropic role of peroxisome proliferator-activated receptor gamma: expression and in vitro effects on enzymatic and hormonal activities in corpora lutea of pseudopregnant rabbits. | Biology of reproduction 20130301 |
Arsenic inhibits the adipogenic differentiation of mesenchymal stem cells by down-regulating peroxisome proliferator-activated receptor gamma and CCAAT enhancer-binding proteins. | Toxicology in vitro : an international journal published in association with BIBRA 20130201 |
Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ. | American journal of physiology. Regulatory, integrative and comparative physiology 20130101 |
Evaluation of a screening system for obesogenic compounds: screening of endocrine disrupting compounds and evaluation of the PPAR dependency of the effect. | PloS one 20130101 |
Triflumizole is an obesogen in mice that acts through peroxisome proliferator activated receptor gamma (PPARγ). | Environmental health perspectives 20121201 |
Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening. | The Journal of biological chemistry 20120921 |
15-Deoxy-Δ¹²,¹⁴-prostaglandin J₂-glycerol, a putative metabolite of 2-arachidonyl glycerol and a peroxisome proliferator-activated receptor γ ligand, modulates nuclear factor of activated T cells. | The Journal of pharmacology and experimental therapeutics 20120901 |
Daidzein has neuroprotective effects through ligand-binding-independent PPARγ activation. | Neurochemistry international 20120701 |
The PPARγ agonist rosiglitazone prevents cognitive impairment by inhibiting astrocyte activation and oxidative stress following pilocarpine-induced status epilepticus. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120601 |
4-Hydroxynonenal differentially regulates adiponectin gene expression and secretion via activating PPARγ and accelerating ubiquitin-proteasome degradation. | Molecular and cellular endocrinology 20120226 |
Telmisartan ameliorates lipopolysaccharide-induced innate immune response through peroxisome proliferator-activated receptor-γ activation in human monocytes. | Journal of hypertension 20120101 |
Activation of peroxisome proliferators-activated receptor δ (PPARδ) promotes blastocyst hatching in mice. | Molecular human reproduction 20111001 |
Stable reporter cell lines for peroxisome proliferator-activated receptor γ (PPARγ)-mediated modulation of gene expression. | Analytical biochemistry 20110701 |
15-Deoxy-delta12,14-prostaglandin J2-glycerol ester, a putative metabolite of 2-arachidonyl glycerol, activates peroxisome proliferator activated receptor gamma. | Molecular pharmacology 20110701 |
The PPARgamma antagonist T0070907 suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms. | Anticancer research 20110301 |
Combined treatment with the Cox-2 inhibitor niflumic acid and PPARγ ligand ciglitazone induces ER stress/caspase-8-mediated apoptosis in human lung cancer cells. | Cancer letters 20110128 |
Clofibrate relaxes the longitudinal smooth muscle of the mouse distal colon through calcium-mediated desensitisation of contractile machinery. | Pharmacology 20110101 |
The nuclear receptor PPARγ individually responds to serotonin- and fatty acid-metabolites. | The EMBO journal 20101006 |
Oxidized low-density lipoprotein activates adipophilin through ERK1/2 signal pathway in RAW264.7 cells. | Acta biochimica et biophysica Sinica 20100901 |
PPARgamma regulates LIF-induced growth and self-renewal of mouse ES cells through Tyk2-Stat3 pathway. | Cellular signalling 20100301 |
Regulation of Immune Responses and Autoimmune Encephalomyelitis by PPARs. | PPAR research 20100101 |
Peroxisome proliferator-activated receptor gamma antagonists decrease Na+ transport via the epithelial Na+ channel. | Molecular pharmacology 20091201 |
(Arylthio)cyclopentenones derivatives prevent glutamate-induced HT22 cell death through a PPAR gamma-dependent pathway. | Brain research 20091103 |
The microtubule-targeting agent T0070907 induces proteasomal degradation of tubulin. | Biochemical and biophysical research communications 20091016 |
Role for PPARgamma in IL-2 inhibition in T cells by Echinacea-derived undeca-2E-ene-8,10-diynoic acid isobutylamide. | International immunopharmacology 20091001 |
Apoptosis induced in HepG2 cells by the synthetic cannabinoid WIN: involvement of the transcription factor PPARgamma. | Biochimie 20090401 |
Synthesis of lipoxin A4 by 5-lipoxygenase mediates PPARgamma-dependent, neuroprotective effects of rosiglitazone in experimental stroke. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090325 |
Tryptophan-containing dipeptide derivatives as potent PPARgamma antagonists: design, synthesis, biological evaluation, and molecular modeling. | European journal of medicinal chemistry 20081201 |
Inhibition of peroxisome proliferator-activated receptor gamma promotes tumorigenesis through activation of the beta-catenin / T cell factor (TCF) pathway in the mouse intestine. | Journal of pharmacological sciences 20081201 |
A PPARs cross-talk concertedly commits C6 glioma cells to oligodendrocytes and induces enzymes involved in myelin synthesis. | Journal of cellular physiology 20081101 |
Inhibition of peroxisome proliferator-activated receptor gamma activity suppresses pancreatic cancer cell motility. | Cancer science 20081001 |
Peroxisome proliferator-activated receptor gamma agonist, rosiglitazone, suppresses CD40 expression and attenuates inflammatory responses after lithium pilocarpine-induced status epilepticus in rats. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20080801 |
JNK- and IkappaB-dependent pathways regulate MCP-1 but not adiponectin release from artificially hypertrophied 3T3-L1 adipocytes preloaded with palmitate in vitro. | American journal of physiology. Endocrinology and metabolism 20080501 |
Activation of cerebral peroxisome proliferator-activated receptors gamma exerts neuroprotection by inhibiting oxidative stress following pilocarpine-induced status epilepticus. | Brain research 20080320 |
Conjugated linoleic acid isomers inhibit platelet-derived growth factor-induced NF-kappaB transactivation and collagen formation in human vascular smooth muscle cells. | European journal of nutrition 20080301 |
Eicosapentaenoic acid inhibits interleukin-6 production in interleukin-1beta-stimulated C6 glioma cells through peroxisome proliferator-activated receptor-gamma. | Prostaglandins, leukotrienes, and essential fatty acids 20080101 |
A peroxisome proliferator-activated receptor gamma antagonist induces vimentin cleavage and inhibits invasion in high-grade hepatocellular carcinoma. | Oncology reports 20071001 |
Peroxisome proliferator-activated receptor gamma interacts with CIITA x RFX5 complex to repress type I collagen gene expression. | The Journal of biological chemistry 20070907 |
Ischemic preconditioning reveals that GLT1/EAAT2 glutamate transporter is a novel PPARgamma target gene involved in neuroprotection. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070701 |
Adiponectin secretion is regulated by SIRT1 and the endoplasmic reticulum oxidoreductase Ero1-L alpha. | Molecular and cellular biology 20070701 |
Peroxisome proliferator-activated receptor-gamma antagonists exhibit potent antiproliferative effects versus many hematopoietic and epithelial cancer cell lines. | Anti-cancer drugs 20070601 |
The role of PPARgamma on restoration of colonic homeostasis after experimental stress-induced inflammation and dysfunction. | Gastroenterology 20070501 |
PPARgamma inhibitors reduce tubulin protein levels by a PPARgamma, PPARdelta and proteasome-independent mechanism, resulting in cell cycle arrest, apoptosis and reduced metastasis of colorectal carcinoma cells. | International journal of cancer 20070201 |
Cannabinoids: a new group of agonists of PPARs. | PPAR research 20070101 |
Synthesis and evaluation of a bromine-76-labeled PPARgamma antagonist 2-bromo-5-nitro-N-phenylbenzamide. | Nuclear medicine and biology 20061001 |
Inhibition of peroxisome proliferator-activated receptor gamma activity in esophageal carcinoma cells results in a drastic decrease of invasive properties. | Cancer science 20060901 |
PPARgamma antagonists reverse the inhibition of neural antigen-specific Th1 response and experimental allergic encephalomyelitis by Ciglitazone and 15-deoxy-Delta12,14-prostaglandin J2. | Journal of neuroimmunology 20060901 |
Altered PPARgamma expression and activation after transient focal ischemia in rats. | The European journal of neuroscience 20060901 |
[Effects of peroxisome proliferator-activated receptor-gamma ligand troglitazone on colon cancer cell growth]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20060818 |
PPARgamma-regulated tight junction development during human urothelial cytodifferentiation. | Journal of cellular physiology 20060801 |
Interleukin-2 suppression by 2-arachidonyl glycerol is mediated through peroxisome proliferator-activated receptor gamma independently of cannabinoid receptors 1 and 2. | Molecular pharmacology 20060701 |
Peroxisome proliferator-activated receptor-gamma antagonists GW9662 and T0070907 reduce the protective effects of lipopolysaccharide preconditioning against organ failure caused by endotoxemia. | Critical care medicine 20060401 |
Activation of CCAAT/enhancer-binding protein (C/EBP) alpha expression by C/EBP beta during adipogenesis requires a peroxisome proliferator-activated receptor-gamma-associated repression of HDAC1 at the C/ebp alpha gene promoter. | The Journal of biological chemistry 20060324 |
CLA isomers inhibit TNFalpha-induced eicosanoid release from human vascular smooth muscle cells via a PPARgamma ligand-like action. | Biochimica et biophysica acta 20060201 |
PPARgamma antagonists exacerbate neural antigen-specific Th1 response and experimental allergic encephalomyelitis. | Journal of neuroimmunology 20051001 |
Critical role of peroxisome proliferator-activated receptor gamma on anoikis and invasion of squamous cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050601 |
Peroxisome proliferator-activated receptor gamma inhibition prevents adhesion to the extracellular matrix and induces anoikis in hepatocellular carcinoma cells. | Cancer research 20050315 |
A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes. | The Journal of pharmacology and experimental therapeutics 20041101 |
T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities. | The Journal of biological chemistry 20020531 |