Home Aminos 6-Chloro-7-((2-morpholinoethyl)amino)quinoline-5,8-dione

6-Chloro-7-((2-morpholinoethyl)amino)quinoline-5,8-dione

CAS No.:
383907-43-5
Catalog Number:
AG00C0BJ
Molecular Formula:
C15H16ClN3O3
Molecular Weight:
321.7588
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$91
- +
2mg
99%
1 week
United States
$140
- +
5mg
≥98%
1 week
United States
$179
- +
10mg
≥98%
1 week
United States
$248
- +
25mg
≥98%
1 week
United States
$491
- +
100mg
99%
1 week
United States
$1715
- +
Product Description
Catalog Number:
AG00C0BJ
Chemical Name:
6-Chloro-7-((2-morpholinoethyl)amino)quinoline-5,8-dione
CAS Number:
383907-43-5
Molecular Formula:
C15H16ClN3O3
Molecular Weight:
321.7588
MDL Number:
MFCD08276924
IUPAC Name:
6-chloro-7-(2-morpholin-4-ylethylamino)quinoline-5,8-dione
InChI:
InChI=1S/C15H16ClN3O3/c16-11-13(18-4-5-19-6-8-22-9-7-19)15(21)12-10(14(11)20)2-1-3-17-12/h1-3,18H,4-9H2
InChI Key:
BMKPVDQDJQWBPD-UHFFFAOYSA-N
SMILES:
ClC1=C(NCCN2CCOCC2)C(=O)c2c(C1=O)cccn2
NSC Number:
663284
Properties
Complexity:
488  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
321.088g/mol
Formal Charge:
0
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
321.761g/mol
Monoisotopic Mass:
321.088g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
71.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.4  
Literature
Title Journal
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters 20130801
Using small molecules to target protein phosphatases. Bioorganic & medicinal chemistry 20110401
Pharmacology and antitumor activity of a quinolinedione Cdc25 phosphatase inhibitor DA3003-1 (NSC 663284). Anticancer research 20070101
The when and wheres of CDC25 phosphatases. Current opinion in cell biology 20060401
Synthesis and biological evaluation of novel heterocyclic quinones as inhibitors of the dual specificity protein phosphatase CDC25C. Bioorganic & medicinal chemistry letters 20060101
Down-regulation of survivin in nitric oxide-induced cell growth inhibition and apoptosis of the human lung carcinoma cells. The Journal of biological chemistry 20040507
NAD(P)H:quinone oxidoreductase-1-dependent and -independent cytotoxicity of potent quinone Cdc25 phosphatase inhibitors. The Journal of pharmacology and experimental therapeutics 20040401
Dual G1 and G2 phase inhibition by a novel, selective Cdc25 inhibitor 6-chloro-7-[corrected](2-morpholin-4-ylethylamino)-quinoline-5,8-dione. The Journal of biological chemistry 20021206
Discovery and biological evaluation of a new family of potent inhibitors of the dual specificity protein phosphatase Cdc25. Journal of medicinal chemistry 20011122
Properties