Ginsenoside CK
| Title | Journal |
|---|---|
| Ginsenoside F1 suppresses astrocytic senescence-associated secretory phenotype. | Chemico-biological interactions 20180301 |
| Production of bioactive ginsenoside compound K in metabolically engineered yeast. | Cell research 20140601 |
| Absorption mechanism of ginsenoside compound K and its butyl and octyl ester prodrugs in Caco-2 cells. | Journal of agricultural and food chemistry 20121017 |
| Inhibition of P-glycoprotein leads to improved oral bioavailability of compound K, an anticancer metabolite of red ginseng extract produced by gut microflora. | Drug metabolism and disposition: the biological fate of chemicals 20120801 |
| Ginsenoside compound K, not Rb1, possesses potential chemopreventive activities in human colorectal cancer. | International journal of oncology 20120601 |
| Compound K, a novel ginsenoside metabolite, inhibits adipocyte differentiation in 3T3-L1 cells: involvement of angiogenesis and MMPs. | Biochemical and biophysical research communications 20120601 |
| Enzymatic biotransformation of ginsenoside Rb1 to compound K by recombinant β-glucosidase from Microbacterium esteraromaticum. | Journal of agricultural and food chemistry 20120411 |
| Anti-inflammatory mechanism of compound K in activated microglia and its neuroprotective effect on experimental stroke in mice. | The Journal of pharmacology and experimental therapeutics 20120401 |
| Co-transformation of Panax major ginsenosides Rb₁ and Rg₁ to minor ginsenosides C-K and F₁ by Cladosporium cladosporioides. | Journal of industrial microbiology & biotechnology 20120401 |
| Intestinal metabolite compound K of panaxoside inhibits the growth of gastric carcinoma by augmenting apoptosis via Bid-mediated mitochondrial pathway. | Journal of cellular and molecular medicine 20120101 |
| Hypoglycemic effect of protopanaxadiol-type ginsenosides and compound K on Type 2 diabetes mice induced by high-fat diet combining with streptozotocin via suppression of hepatic gluconeogenesis. | Fitoterapia 20120101 |
| Snailase preparation of ginsenoside M1 from protopanaxadiol-type ginsenoside and their protective effects against CCl4-induced chronic hepatotoxicity in mice. | Molecules (Basel, Switzerland) 20111206 |
| Ginsenoside metabolite compound K differentially antagonizing tumor necrosis factor-α-induced monocyte-endothelial trafficking. | Chemico-biological interactions 20111015 |
| Subchronic toxicity studies with ginsenoside compound K delivered to dogs via intravenous administration. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801 |
| Ginsenoside Rb1 and its metabolite compound K inhibit IRAK-1 activation--the key step of inflammation. | Biochemical pharmacology 20110801 |
| Inhibition of JAK1/STAT3 signaling mediates compound K-induced apoptosis in human multiple myeloma U266 cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110601 |
| Compound K, a metabolite of ginsenosides, induces cardiac protection mediated nitric oxide via Akt/PI3K pathway. | Life sciences 20110411 |
| Ginsenoside compound K attenuates metastatic growth of hepatocellular carcinoma, which is associated with the translocation of nuclear factor-κB p65 and reduction of matrix metalloproteinase-2/9. | Planta medica 20110301 |
| Compound K increases type I procollagen level and decreases matrix metalloproteinase-1 activity and level in ultraviolet-A-irradiated fibroblasts. | Journal of the Formosan Medical Association = Taiwan yi zhi 20110301 |
| Production of aglycon protopanaxadiol via compound K by a thermostable β-glycosidase from Pyrococcus furiosus. | Applied microbiology and biotechnology 20110201 |
| Post-exposure treatment with ginsenoside compound K ameliorates auditory functional injury associated with noise-induced hearing loss in mice. | Neuroscience letters 20110107 |
| Compound K, a metabolite of ginsenosides, facilitates spontaneous GABA release onto CA3 pyramidal neurons. | Journal of neurochemistry 20100801 |
| Effect and mechanism of ginsenosides CK and Rg1 on stimulation of glucose uptake in 3T3-L1 adipocytes. | Journal of agricultural and food chemistry 20100526 |
| Isatis tinctoria L. combined with co-stimulatory molecules blockade prolongs survival of cardiac allografts in alloantigen-primed mice. | Transplant immunology 20100501 |
| Compound K inhibits basic fibroblast growth factor-induced angiogenesis via regulation of p38 mitogen activated protein kinase and AKT in human umbilical vein endothelial cells. | Biological & pharmaceutical bulletin 20100101 |
| Compound K, a metabolite of ginseng saponin, induces mitochondria-dependent and caspase-dependent apoptosis via the generation of reactive oxygen species in human colon cancer cells. | International journal of molecular sciences 20100101 |
| Compound K induces apoptosis via CAMK-IV/AMPK pathways in HT-29 colon cancer cells. | Journal of agricultural and food chemistry 20091125 |
| Glucocorticoid receptor agonist compound K regulates Dectin-1-dependent inflammatory signaling through inhibition of reactive oxygen species. | Life sciences 20091021 |
| Effect of compound K, a metabolite of ginseng saponin, combined with gamma-ray radiation in human lung cancer cells in vitro and in vivo. | Journal of agricultural and food chemistry 20090708 |
| Compound K, intestinal metabolite of ginsenoside, attenuates hepatic lipid accumulation via AMPK activation in human hepatoma cells. | Journal of agricultural and food chemistry 20090225 |
| Compound K, a metabolite of ginseng saponin, induces apoptosis via caspase-8-dependent pathway in HL-60 human leukemia cells. | BMC cancer 20090101 |
| Compound K suppresses ultraviolet radiation-induced apoptosis by inducing DNA repair in human keratinocytes. | Archives of pharmacal research 20081101 |
| The ginsenoside metabolite compound K, a novel agonist of glucocorticoid receptor, induces tolerance to endotoxin-induced lethal shock. | Journal of cellular and molecular medicine 20080901 |
| Development and validation of a reversed-phase HPLC method for quantitative determination of ginsenosides Rb1, Rd, F2, and compound K during the process of biotransformation of ginsenoside Rb1. | Journal of separation science 20080401 |
| Biotransformation of Panax notoginseng saponins into ginsenoside compound K production by Paecilomyces bainier sp. 229. | Journal of applied microbiology 20080301 |
| A ginseng saponin metabolite suppresses tumor necrosis factor-alpha-promoted metastasis by suppressing nuclear factor-kappaB signaling in murine colon cancer cells. | Oncology reports 20080301 |
| Compound K enhances insulin secretion with beneficial metabolic effects in db/db mice. | Journal of agricultural and food chemistry 20071226 |
| Transformation of bioactive compounds by Fusarium sacchari fungus isolated from the soil-cultivated ginseng. | Journal of agricultural and food chemistry 20071114 |
| Anti-diabetic effects of compound K versus metformin versus compound K-metformin combination therapy in diabetic db/db mice. | Biological & pharmaceutical bulletin 20071101 |
| Marked production of ginsenosides Rd, F2, Rg3, and compound K by enzymatic method. | Chemical & pharmaceutical bulletin 20071001 |
| [Advances in the study of ginsenoside compound K]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070901 |
| Ginsenosides compound K and Rh(2) inhibit tumor necrosis factor-alpha-induced activation of the NF-kappaB and JNK pathways in human astroglial cells. | Neuroscience letters 20070621 |
| Deletion of the sphingosine kinase-1 gene influences cell fate during hypoxia and glucose deprivation in adult mouse cardiomyocytes. | Cardiovascular research 20070401 |
| Effect of ginsenosides on glucose uptake in human Caco-2 cells is mediated through altered Na+/glucose cotransporter 1 expression. | Journal of agricultural and food chemistry 20070307 |
| Purification and characterization of new special ginsenosidase hydrolyzing multi-glycisides of protopanaxadiol ginsenosides, ginsenosidase type I. | Chemical & pharmaceutical bulletin 20070201 |
| A ginsenoside metabolite, 20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol, triggers apoptosis in activated rat hepatic stellate cells via caspase-3 activation. | Planta medica 20061001 |
| Ginseng saponin metabolite suppresses phorbol ester-induced matrix metalloproteinase-9 expression through inhibition of activator protein-1 and mitogen-activated protein kinase signaling pathways in human astroglioma cells. | International journal of cancer 20060115 |
| Pharmacokinetics of a ginseng saponin metabolite compound K in rats. | Biopharmaceutics & drug disposition 20060101 |
| Hepatoprotective effect of ginsenoside Rb1 and compound K on tert-butyl hydroperoxide-induced liver injury. | Liver international : official journal of the International Association for the Study of the Liver 20051001 |
| Antipruritic effect of ginsenoside rb1 and compound k in scratching behavior mouse models. | Journal of pharmacological sciences 20050901 |
| Effect of ginsenoside Rb1 and compound K in chronic oxazolone-induced mouse dermatitis. | International immunopharmacology 20050701 |
| [Determination of ginsenoside compound-K by reversed-phase high performance liquid chromatography]. | Se pu = Chinese journal of chromatography 20050501 |
| Inhibitory effect of ginsenoside Rb1 and compound K on NO and prostaglandin E2 biosyntheses of RAW264.7 cells induced by lipopolysaccharide. | Biological & pharmaceutical bulletin 20050401 |
| Metabolic activities of ginsenoside Rb1, baicalin, glycyrrhizin and geniposide to their bioactive compounds by human intestinal microflora. | Biological & pharmaceutical bulletin 20041001 |
| Compound K induces expression of hyaluronan synthase 2 gene in transformed human keratinocytes and increases hyaluronan in hairless mouse skin. | Biochemical and biophysical research communications 20040402 |
| Differential effect of ginsenoside metabolites on the 5-HT3A receptor-mediated ion current in Xenopus oocytes. | Molecules and cells 20040227 |
| A novel ginseng saponin metabolite induces apoptosis and down-regulates fibroblast growth factor receptor 3 in myeloma cells. | International journal of oncology 20031001 |
| Differential effect of bovine serum albumin on ginsenoside metabolite-induced inhibition of alpha3beta4 nicotinic acetylcholine receptor expressed in Xenopus oocytes. | Archives of pharmacal research 20031001 |
| Degradation of ginsenosides in humans after oral administration. | Drug metabolism and disposition: the biological fate of chemicals 20030801 |
| Inhibition of intracerebroventricular injection stress-induced plasma corticosterone levels by intracerebroventricularly administered compound K, a ginseng saponin metabolite, in mice. | Biological & pharmaceutical bulletin 20030701 |
| Ginseng intestinal metabolite-I (GIM-I) reduces doxorubicin toxicity in the mouse testis. | Reproductive toxicology (Elmsford, N.Y.) 20020101 |
| The antimetastatic and immunomodulating activities of ginseng minor glycosides. | Doklady. Biochemistry and biophysics 20010101 |