8-HYDROXYGUANOSINE
| Title | Journal |
|---|---|
| Experimental evidence of oxidative stress in patients with l-2-hydroxyglutaric aciduria and that l-carnitine attenuates in vitro DNA damage caused by d-2-hydroxyglutaric and l-2-hydroxyglutaric acids. | Toxicology in vitro : an international journal published in association with BIBRA 20170801 |
| Oxidative damage of DNA, RNA and their metabolites in leukocytes, plasma and urine of Macaca mulatta: 8-oxoguanosine in urine is a useful marker for aging. | Free radical research 20120901 |
| Age-dependent increases in the oxidative damage of DNA, RNA, and their metabolites in normal and senescence-accelerated mice analyzed by LC-MS/MS: urinary 8-oxoguanosine as a novel biomarker of aging. | Free radical biology & medicine 20120501 |
| RNA modifications by oxidation: a novel disease mechanism? | Free radical biology & medicine 20120415 |
| Lifetimes and reaction pathways of guanine radical cations and neutral guanine radicals in an oligonucleotide in aqueous solutions. | Journal of the American Chemical Society 20120314 |
| Oxidative damage to guanine nucleosides following combination chemotherapy with 5-fluorouracil and oxaliplatin. | Cancer chemotherapy and pharmacology 20120201 |
| Long-term perturbation of muscle iron homeostasis following hindlimb suspension in old rats is associated with high levels of oxidative stress and impaired recovery from atrophy. | Experimental gerontology 20120101 |
| Accumulation of exogenous amyloid-beta peptide in hippocampal mitochondria causes their dysfunction: a protective role for melatonin. | Oxidative medicine and cellular longevity 20120101 |
| Structure of a Nudix hydrolase (MutT) in the Mg(2+)-bound state from Bartonella henselae, the bacterium responsible for cat scratch fever. | Acta crystallographica. Section F, Structural biology and crystallization communications 20110901 |
| Genetic and environmental influences on oxidative damage assessed in elderly Danish twins. | Free radical biology & medicine 20110601 |
| Characterization of 2'-deoxyguanosine oxidation products observed in the Fenton-like system Cu(II)/H2O2/reductant in nucleoside and oligodeoxynucleotide contexts. | Organic & biomolecular chemistry 20110507 |
| Long-term effects of Irbesartan treatment and smoking on nucleic acid oxidation in patients with type 2 diabetes and microalbuminuria: an Irbesartan in patients with type 2 diabetes and Microalbuminuria (IRMA 2) substudy. | Diabetes care 20110501 |
| Carcinogenic heavy metals, As3+ and Cr6+, increase affinity of nuclear mono-ubiquitinated annexin A1 for DNA containing 8-oxo-guanosine, and promote translesion DNA synthesis. | Toxicology and applied pharmacology 20110415 |
| Reference ranges of urinary biomarkers of oxidized guanine in (2'-deoxy)ribonucleotides and nucleic acids. | Free radical biology & medicine 20110115 |
| NAD(P)H: quinone oxidoreductase 1 deficiency conjoint with marginal vitamin C deficiency causes cigarette smoke induced myelodysplastic syndromes. | PloS one 20110101 |
| Association between urinary excretion of cortisol and markers of oxidatively damaged DNA and RNA in humans. | PloS one 20110101 |
| Use of specific chemical reagents for detection of modified nucleotides in RNA. | Journal of nucleic acids 20110101 |
| Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats. | PloS one 20110101 |
| Pathogenic triad in COPD: oxidative stress, protease-antiprotease imbalance, and inflammation. | International journal of chronic obstructive pulmonary disease 20110101 |
| Intestinal metaplasia -the effect of Acid on the gastric mucosa and gastric carcinogenesis-. | Journal of toxicologic pathology 20100901 |
| Oxidative damage to DNA and lipids as biomarkers of exposure to air pollution. | Environmental health perspectives 20100801 |
| A nuclear family A DNA polymerase from Entamoeba histolytica bypasses thymine glycol. | PLoS neglected tropical diseases 20100801 |
| Quantitative determination of urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine, 8-oxo-7,8-dihydroguanine, 8-oxo-7,8-dihydroguanosine, and their non-oxidized forms: daily concentration profile in healthy volunteers. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20100501 |
| Occupational exposure to low levels of benzene: Biomarkers of exposure and nucleic acid oxidation and their modulation by polymorphic xenobiotic metabolizing enzymes. | Toxicology letters 20100401 |
| Hydrogen sulfide induces oxidative damage to RNA and DNA in a sulfide-tolerant marine invertebrate. | Physiological and biochemical zoology : PBZ 20100101 |
| Urinary excretion of biomarkers of oxidatively damaged DNA and RNA in hereditary hemochromatosis. | Free radical biology & medicine 20091015 |
| Biomarkers of nucleic acid oxidation, polymorphism in, and expression of, hOGG1 gene in styrene-exposed workers. | Toxicology letters 20091008 |
| Automated method for the direct analysis of 8-oxo-guanosine and 8-oxo-2'-deoxyguanosine in human urine using ultraperformance liquid chromatography and tandem mass spectrometry. | Free radical biology & medicine 20090901 |
| Incorporation of 8-hydroxyguanosine (8-oxo-7,8-dihydroguanosine) 5'-triphosphate by bacterial and human RNA polymerases. | Free radical biology & medicine 20090615 |
| Coronary intraplaque hemorrhage evokes a novel atheroprotective macrophage phenotype. | The American journal of pathology 20090301 |
| Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. | PloS one 20090101 |
| Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS. | PloS one 20080101 |
| Iron accumulation with age, oxidative stress and functional decline. | PloS one 20080101 |
| Lack of association of colonic epithelium telomere length and oxidative DNA damage in Type 2 diabetes under good metabolic control. | BMC endocrine disorders 20080101 |
| AtNUDX1, an 8-oxo-7,8-dihydro-2'-deoxyguanosine 5'-triphosphate pyrophosphohydrolase, is responsible for eliminating oxidized nucleotides in Arabidopsis. | Plant & cell physiology 20071001 |
| Cyclophosphamide-induced apoptosis in COV434 human granulosa cells involves oxidative stress and glutathione depletion. | Toxicological sciences : an official journal of the Society of Toxicology 20070701 |
| In vitro ligation of oligodeoxynucleotides containing C8-oxidized purine lesions using bacteriophage T4 DNA ligase. | Biochemistry 20070327 |
| Effect of olive oils on biomarkers of oxidative DNA stress in Northern and Southern Europeans. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070101 |
| A method to determine RNA and DNA oxidation simultaneously by HPLC-ECD: greater RNA than DNA oxidation in rat liver after doxorubicin administration. | Biological chemistry 20060101 |
| Hepatic oxidative stress during aging: effects of 8% long-term calorie restriction and lifelong exercise. | Antioxidants & redox signaling 20060101 |
| Consequences of low birthweight on urinary excretion of DNA markers of oxidative stress in young men. | Scandinavian journal of clinical and laboratory investigation 20060101 |
| A lysine residue in the fingers subdomain of T7 DNA polymerase modulates the miscoding potential of 8-oxo-7,8-dihydroguanosine. | Structure (London, England : 1993) 20051101 |
| Characterization of 5-hydroxy-8-oxo-7,8-dihydroguanosine in the photosensitized oxidation of 8-oxo-7,8-dihydroguanosine and its rearrangement to spiroiminodihydantoin. | Journal of the American Chemical Society 20041229 |
| DNA . RNA heteroduplex containing 8-oxo-7,8-dihydroguanosine: base pairing, structures, and thermodynamic stability. | Journal of biochemistry and molecular biology 20041130 |
| Spermine participates in oxidative damage of guanosine and 8-oxoguanosine leading to deoxyribosylurea formation. | Journal of the American Chemical Society 20040811 |
| Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing phenyl(trifluoromethyl)diazirine groups. | European journal of biochemistry 20030701 |
| Use of crosslinking for revealing the DNA phosphate groups forming specific contacts with the E. coli Fpg protein. | Biochimie 20030501 |
| Low-temperature photosensitized oxidation of a guanosine derivative and formation of an imidazole ring-opened product. | Journal of the American Chemical Society 20020417 |
| Formation of 8-nitroguanosine in cellular RNA as a biomarker of exposure to reactive nitrogen species. | Chemico-biological interactions 20020220 |
| The pH-dependent role of superoxide in riboflavin-catalyzed photooxidation of 8-oxo-7,8-dihydroguanosine. | Organic letters 20010906 |
| Characterization of hydantoin products from one-electron oxidation of 8-oxo-7,8-dihydroguanosine in a nucleoside model. | Chemical research in toxicology 20010701 |
| Spiroiminodihydantoin is the major product of the 8-oxo-7,8-dihydroguanosine reaction with peroxynitrite in the presence of thiols and guanosine photooxidation by methylene blue. | Organic letters 20010405 |
| Increased oxidative DNA damage in mammary tumor cells by continuous epidermal growth factor stimulation. | Journal of the National Cancer Institute 20010207 |