8-CHLOROADENOSINE
Title | Journal |
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Regioselective enzymatic undecylenoylation of 8-chloroadenosine and its analogs with biomass-based 2-methyltetrahydrofuran as solvent. | Bioresource technology 20120801 |
E2F1 enhances 8-chloro-adenosine-induced G2/M arrest and apoptosis in A549 and H1299 lung cancer cells. | Biochemistry. Biokhimiia 20120301 |
Integrative gene expression profiling reveals G6PD-mediated resistance to RNA-directed nucleoside analogues in B-cell neoplasms. | PloS one 20120101 |
A unique RNA-directed nucleoside analog is cytotoxic to breast cancer cells and depletes cyclin E levels. | Breast cancer research and treatment 20100601 |
Intracellular succinylation of 8-chloroadenosine and its effect on fumarate levels. | The Journal of biological chemistry 20100312 |
Preclinical activity of 8-chloroadenosine with mantle cell lymphoma: roles of energy depletion and inhibition of DNA and RNA synthesis. | British journal of haematology 20091101 |
Inhibition of ATP synthase by chlorinated adenosine analogue. | Biochemical pharmacology 20090915 |
Inhibition of CHK1 kinase by Gö6976 converts 8-chloro-adenosine-induced G2/M arrest into S arrest in human myelocytic leukemia K562 cells. | Biochemical pharmacology 20090301 |
8-Chloro-adenosine-induced E2F1 promotes p14ARF gene activation in H1299 cells through displacing Sp1 from multiple overlapping E2F1/Sp1 sites. | Journal of cellular biochemistry 20090215 |
Inhibition of topoisomerase II by 8-chloro-adenosine triphosphate induces DNA double-stranded breaks in 8-chloro-adenosine-exposed human myelocytic leukemia K562 cells. | Biochemical pharmacology 20090201 |
Induction of p14ARF by E2F1 contributes to 8-chloro-adenosine-induced apoptosis in human lung cancer H1299 cells. | Chemotherapy 20090101 |
Protein kinase A-independent inhibition of proliferation and induction of apoptosis in human thyroid cancer cells by 8-Cl-adenosine. | The Journal of clinical endocrinology and metabolism 20080301 |
Multiple myeloma cell killing by depletion of the MET receptor tyrosine kinase. | Cancer research 20071015 |
8-Chloro-adenosine inhibits growth at least partly by interfering with actin polymerization in cultured human lung cancer cells. | Biochemical pharmacology 20060828 |
8-chloroadenosine induced HL-60 cell growth inhibition, differentiation, and G(0)/G(1) arrest involves attenuated cyclin D1 and telomerase and up-regulated p21(WAF1/CIP1). | Journal of cellular biochemistry 20060101 |
The combination of sulfinosine and 8-Cl-cAMP induces synergistic cell growth inhibition of the human neuroblastoma cell line in vitro. | Investigational new drugs 20060101 |
[Mechanisms of sensitization by 8-chloro-adenosine of human tumor cells to TRAIL-induced apoptosis]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20051001 |
8-Chloro-cyclic AMP-induced growth inhibition and apoptosis is mediated by p38 mitogen-activated protein kinase activation in HL60 cells. | Cancer research 20050601 |
[Preparation of 8-chloro-adenosine long circulation liposomes and its pharmacokinetics in rats]. | Yao xue xue bao = Acta pharmaceutica Sinica 20050401 |
8-Cl-cAMP and its metabolite, 8-Cl-adenosine induce growth inhibition in mouse fibroblast DT cells through the same pathways: protein kinase C activation and cyclin B down-regulation. | Journal of cellular physiology 20041101 |
8-Chloro-adenosine sensitizes a human hepatoma cell line to TRAIL-induced apoptosis by caspase-dependent and -independent pathways. | Oncology reports 20040701 |
[Inhibition of 8-chloroadenosine on proteasome activity of HL-60 cells]. | Ai zheng = Aizheng = Chinese journal of cancer 20040201 |
Anti-cowpox virus activities of certain adenosine analogs, arabinofuranosyl nucleosides, and 2'-fluoro-arabinofuranosyl nucleosides. | Nucleosides, nucleotides & nucleic acids 20040101 |
8-Cl-Adenosine enhances 1,25-dihydroxyvitamin D3-induced growth inhibition without affecting 1,25-dihydroxyvitamin D3-stimulated differentiation of primary mouse epidermal keratinocytes. | BMC pharmacology 20040101 |
[The inhibitory effect of 8-chloroadenosine on tumor necrosis factor-induced proto-oncogene expression of retinal pigment epithelial cells]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20031201 |
RNA-directed actions of 8-chloro-adenosine in multiple myeloma cells. | Cancer research 20031115 |
[8-Chloro-adenosine increases the activity of transcription factor CREB by modification of phosphorylation]. | Ai zheng = Aizheng = Chinese journal of cancer 20030401 |
Anti-proliferative effects of 8-chloro-cAMP and other cAMP analogs are unrelated to their effects on protein kinase A regulatory subunit expression. | Journal of cellular physiology 20020801 |
Plasma and cellular pharmacology of 8-chloro-adenosine in mice and rats. | Cancer chemotherapy and pharmacology 20020801 |
Genome-wide expression profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray. | Experimental & molecular medicine 20020731 |
Synthesis and hybridization properties of RNA containing 8-chloroadenosine. | Nucleosides, nucleotides & nucleic acids 20020101 |
8-Cl-adenosine is an active metabolite of 8-Cl-cAMP responsible for its in vitro antiproliferative effects on CHO mutants hypersensitive to cytostatic drugs. | Cancer chemotherapy and pharmacology 20011201 |
8-chloro-cAMP and 8-chloro-adenosine act by the same mechanism in multiple myeloma cells. | Cancer research 20010715 |
8-Cl-adenosine mediated cytotoxicity and sensitization of T-lymphoblastic leukemia cells to TNFalpha-induced apoptosis is via inactivation of NF-kappaB. | Leukemia research 20010501 |