Home Other Building Blocks 2,2',3,4,4',5,5'-HEPTACHLOROBIPHENYL

2,2',3,4,4',5,5'-HEPTACHLOROBIPHENYL

CAS No.:
35065-29-3
Catalog Number:
AG00BY12
Molecular Formula:
Molecular Weight:
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Product Description
Catalog Number:
AG00BY12
Chemical Name:
2,2',3,4,4',5,5'-HEPTACHLOROBIPHENYL
CAS Number:
35065-29-3
MDL Number:
MFCD00055551
IUPAC Name:
1,2,3,4-tetrachloro-5-(2,4,5-trichlorophenyl)benzene
InChI:
InChI=1S/C12H3Cl7/c13-6-3-8(15)7(14)1-4(6)5-2-9(16)11(18)12(19)10(5)17/h1-3H
InChI Key:
WBHQEUPUMONIKF-UHFFFAOYSA-N
UNII:
52I0CG8IQX
Properties
Complexity:
313  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
393.802g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
0
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
395.306g/mol
Monoisotopic Mass:
391.805g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
7.9  
Literature
Title Journal
Lactational exposure of mice to low levels of non-dioxin-like polychlorinated biphenyls increases susceptibility to neuronal stress at a mature age. Neurotoxicology 20160301
Exposure to Endocrine-Disrupting Chemicals during Pregnancy and Weight at 7 Years of Age: A Multi-pollutant Approach. Environmental health perspectives 20151001
Effect-based assessment of persistent organic pollutant and pesticide dumpsite using mammalian CALUX reporter cell lines. Environmental science and pollution research international 20151001
Hydroxyl metabolite of PCB 180 induces DNA damage signaling and enhances the DNA damaging effect of benzo[a]pyrene. Chemico-biological interactions 20150905
Polychlorinated Biphenyls (PCB 101, 153, and 180) Impair Murine Macrophage Responsiveness to Lipopolysaccharide: Involvement of NF-κB Pathway. Toxicological sciences : an official journal of the Society of Toxicology 20150901
Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling. Neurotoxicology 20150901
Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways. Toxicology letters 20150402
Lactational exposure to low levels of the six indicator non-dioxin-like polychlorinated biphenyls induces DNA damage and repression of neuronal activity, in juvenile male mice. Toxicology 20150203
Polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) alter leptin signaling and lipid metabolism in differentiated 3T3-L1 adipocytes. Toxicology and applied pharmacology 20140915
Correlation of gene expression and contaminant concentrations in wild largescale suckers: a field-based study. The Science of the total environment 20140615
Dopamine-dependent behavior in adult rats after perinatal exposure to purity-controlled polychlorinated biphenyl congeners (PCB52 and PCB180). Toxicology letters 20140103
Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes. Toxicology and applied pharmacology 20131001
Sexually dimorphic behavior after developmental exposure to characterize endocrine-mediated effects of different non-dioxin-like PCBs in rats. Toxicology 20130906
Perinatal exposure to purity-controlled polychlorinated biphenyl 52, 138, or 180 alters toxicogenomic profiles in peripheral blood of rats after 4 months. Chemical research in toxicology 20130819
Neurodevelopmental and behavioral toxicity via lactational exposure to the sum of six indicator non-dioxin-like-polychlorinated biphenyls (∑6 NDL-PCBs) in mice. Toxicology 20120904
Non-coplanar polychlorinated biphenyls (PCBs) are direct agonists for the human pregnane-X receptor and constitutive androstane receptor, and activate target gene expression in a tissue-specific manner. Toxicology and applied pharmacology 20120815
Biological monitoring of indoor-exposure to dioxin-like and non-dioxin-like polychlorinated biphenyls (PCB) in a public building. Toxicology letters 20120813
Long-term trends of continental-scale PCB patterns studied using a global atmosphere-ocean general circulation model. Environmental science and pollution research international 20120701
Association of serum levels of polychlorinated biphenyls with IL-8 mRNA expression in blood samples from asthmatic and non-asthmatic Japanese children. Chemosphere 20120601
Non-dioxin-like polychlorinated biphenyls interfere with neuronal differentiation of embryonic neural stem cells. Toxicological sciences : an official journal of the Society of Toxicology 20111101
Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs. Toxicology letters 20111010
Transcriptomics identifies differences between ultrapure non-dioxin-like polychlorinated biphenyls (PCBs) and dioxin-like PCB126 in cultured peripheral blood mononuclear cells. Toxicology 20110905
In utero and lactational exposure to PCBs in mice: adult offspring show altered learning and memory depending on Cyp1a2 and Ahr genotypes. Environmental health perspectives 20110901
Auditory effects of developmental exposure to purity-controlled polychlorinated biphenyls (PCB52 and PCB180) in rats. Toxicological sciences : an official journal of the Society of Toxicology 20110701
Hepatic effects of a highly purified 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in male and female rats. Toxicology 20110618
In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans. Toxicological sciences : an official journal of the Society of Toxicology 20110501
Effects of non-dioxin-like polychlorinated biphenyl congeners (PCB 101, PCB 153 and PCB 180) alone or mixed on J774A.1 macrophage cell line: modification of apoptotic pathway. Toxicology letters 20110410
Prenatal PCBs disrupt early neuroendocrine development of the rat hypothalamus. Toxicology and applied pharmacology 20110401
Endocrine disruption of brain sexual differentiation by developmental PCB exposure. Endocrinology 20110201
In utero and lactational exposure to a complex mixture of polychlorinated biphenyls: toxicity in pups dependent on the Cyp1a2 and Ahr genotypes. Toxicological sciences : an official journal of the Society of Toxicology 20110101
Differential long-term effects of developmental exposure to polychlorinated biphenyls 52, 138 or 180 on motor activity and neurotransmission. Gender dependence and mechanisms involved. Neurochemistry international 20110101
Postnatal exposure to PCB 153 and PCB 180, but not to PCB 52, produces changes in activity level and stimulus control in outbred male Wistar Kyoto rats. Behavioral and brain functions : BBF 20110101
Activation and potentiation of human GABAA receptors by non-dioxin-like PCBs depends on chlorination pattern. Toxicological sciences : an official journal of the Society of Toxicology 20101101
DDE in mothers' blood during pregnancy and lower respiratory tract infections in their infants. Epidemiology (Cambridge, Mass.) 20100901
POP accumulation in the food chain: Integrated risk model for sewage sludge application in agricultural soils. Environment international 20100801
Developmental exposure to polychlorinated biphenyls 52, 138 or 180 affects differentially learning or motor coordination in adult rats. Mechanisms involved. Neuroscience 20100602
Polychlorinated biphenyls PCB 52, PCB 180, and PCB 138 impair the glutamate-nitric oxide-cGMP pathway in cerebellar neurons in culture by different mechanisms. Chemical research in toxicology 20100419
Determination of organochlorine pesticide and polychlorinated biphenyl levels in adipose tissue of infertile men. Environmental monitoring and assessment 20100301
Evaluation of an hPXR reporter gene assay for the detection of aquatic emerging pollutants: screening of chemicals and application to water samples. Analytical and bioanalytical chemistry 20100101
Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells. Chemico-biological interactions 20091210
Thyroid function and plasma concentrations of polyhalogenated compounds in Inuit adults. Environmental health perspectives 20090901
Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat Part 2: Effects on reproductive parameters, on sex behavior, on memory retention and on hypothalamic expression of aromatase and 5alpha-reductases in the offspring. Toxicology and applied pharmacology 20090815
Transactivation potencies of Baikal seal constitutive active/androstane receptor by persistent organic pollutants and brominated flame retardants. Environmental science & technology 20090815
Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat: Part 1: Effects on somatic growth, growth hormone-axis activity and bone mass in the offspring. Toxicology and applied pharmacology 20090601
A physiologically based pharmacokinetic model for the assessment of infant exposure to persistent organic pollutants in epidemiologic studies. Environmental health perspectives 20090301
Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma. Blood 20090226
Association of organochlorine pesticides with peripheral neuropathy in patients with diabetes or impaired fasting glucose. Diabetes 20081101
Serum concentrations of indicator PCB congeners in the Czech adult population. Chemosphere 20080701
Polychlorinated biphenyl exposure and neuropsychological status among older residents of upper Hudson River communities. Environmental health perspectives 20080201
Dioxin-like compound load in bulk of Chlorofen--a technical chlorobiphenyl formulation from Poland. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20071101
Food web-specific biomagnification of persistent organic pollutants. Science (New York, N.Y.) 20070713
Constitutive androstane receptor (CAR) as a potential sensing biomarker of persistent organic pollutants (POPs) in aquatic mammal: molecular characterization, expression level, and ligand profiling in Baikal seal (Pusa sibirica). Toxicological sciences : an official journal of the Society of Toxicology 20061101
PCB exposure and in vivo CYP1A2 activity among Native Americans. Environmental health perspectives 20050301
Uptake and tissue-specific distribution of selected polychlorinated biphenyls in developing chicken embryos. Environmental toxicology and chemistry 20050301
Lineage-specific effects of polychlorinated biphenyls (PCB) on gene expression in the rabbit blastocyst. Reproductive toxicology (Elmsford, N.Y.) 20050101
Retention indexes for temperature-programmed gas chromatography of polychlorinated biphenyls. Analytical chemistry 20040915
Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts. Environmental health : a global access science source 20030101
Inhibition of E2-induced expression of BRCA1 by persistent organochlorines. Breast cancer research : BCR 20020101
Effect of highly bioaccumulated polychlorinated biphenyl congeners on estrogen and androgen receptor activity. Toxicology 20010214
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