Ah 6809
Title | Journal |
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Leptin induces CREB-dependent aromatase activation through COX-2 expression in breast cancer cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170801 |
Role of hypoxia-inducible factor 1, α subunit and cAMP-response element binding protein 1 in synergistic release of interleukin 8 by prostaglandin E2 and nickel in lung fibroblasts. | American journal of respiratory cell and molecular biology 20130701 |
Murine corneal stroma cells suppress bone marrow-derived dendritic cells maturation in vitro. | Chinese medical journal 20120601 |
The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination. | Journal of neurochemistry 20120501 |
Prostaglandin E2 blocks menadione-induced apoptosis through the Ras/Raf/Erk signaling pathway in promonocytic leukemia cell lines. | Molecules and cells 20120430 |
Prostaglandin E2 restrains macrophage maturation via E prostanoid receptor 2/protein kinase A signaling. | Blood 20120308 |
Influence of influenza A infection on capsaicin-induced responses in murine airways. | The Journal of pharmacology and experimental therapeutics 20120201 |
Prostaglandin E2 induces spontaneous rhythmic activity in mouse urinary bladder independently of efferent nerves. | British journal of pharmacology 20120101 |
Acute effects of prostaglandin E1 and E2 on vascular reactivity and blood flow in situ in the chick chorioallantoic membrane. | Prostaglandins, leukotrienes, and essential fatty acids 20120101 |
Primary human airway epithelial cell-dependent inhibition of human lung mast cell degranulation. | PloS one 20120101 |
PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment. | Cancer research 20111215 |
EP4 receptor as a new target for bronchodilator therapy. | Thorax 20111201 |
SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons. | Toxicological sciences : an official journal of the Society of Toxicology 20111201 |
Thromboxane and isoprostane share the same prostanoid receptors to increase human placental tone. | Placenta 20111201 |
Thromboxane prostanoid receptor activation amplifies airway stretch-activated contractions assessed in perfused intact bovine bronchial segments. | The Journal of pharmacology and experimental therapeutics 20111001 |
Suppressive effect of aqueous humor on lipopolysaccharide-induced dendritic cell maturation. | Japanese journal of ophthalmology 20110901 |
Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway. | The Journal of biological chemistry 20110121 |
Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer. | Journal of experimental & clinical cancer research : CR 20110101 |
Inhibitory influence of protease-activated receptor 2 and E-prostanoid receptor stimulants in lipopolysaccharide models of acute airway inflammation. | The Journal of pharmacology and experimental therapeutics 20101101 |
The role of cyclooxygenase-2-dependent signaling via cyclic AMP response element activation on aromatase up-regulation by o,p'-DDT in human breast cancer cells. | Toxicology letters 20101020 |
Jack bean urease alters serotonin-induced effects on Rhodnius prolixus anterior midgut. | Journal of insect physiology 20100901 |
Functional and molecular characterization of prostaglandin E2 dilatory receptors in the rat craniovascular system in relevance to migraine. | Cephalalgia : an international journal of headache 20100901 |
Inducible cyclooxygenase released prostaglandin E2 modulates the severity of infection caused by Streptococcus pyogenes. | Journal of immunology (Baltimore, Md. : 1950) 20100815 |
Selective blockade of prostaglandin E2 receptors EP2 and EP4 signaling inhibits proliferation of human endometriotic epithelial cells and stromal cells through distinct cell cycle arrest. | Fertility and sterility 20100515 |
Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERalpha pathway in human breast cancer cells. | Toxicological sciences : an official journal of the Society of Toxicology 20100401 |
Human papillomavirus type 16 E5 protein inhibits hydrogen-peroxide-induced apoptosis by stimulating ubiquitin-proteasome-mediated degradation of Bax in human cervical cancer cells. | Carcinogenesis 20100301 |
Age-related changes in isoprostane-mediated relaxation of piglet blood vessels. | Frontiers in bioscience (Elite edition) 20100101 |
Expression of cyclooxygenase-1/-2, microsomal prostaglandin-E synthase-1 and E-prostanoid receptor 2 and regulation of inflammatory mediators by PGE(2) in the amoeboid microglia in hypoxic postnatal rats and murine BV-2 cells. | Neuroscience 20091215 |
Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo. | Neurochemical research 20091201 |
Differential afferent sensitivity to mucosal lipopolysaccharide from Salmonella typhimurium and Escherichia coli in the rat jejunum. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20091201 |
Involvement of cyclooxygenase-2 in carbachol-induced positive inotropic response in mouse isolated left atrium. | The Journal of pharmacology and experimental therapeutics 20091201 |
Prostaglandin E2 mediates cough via the EP3 receptor: implications for future disease therapy. | American journal of respiratory and critical care medicine 20091115 |
Chronic methionine load-induced hyperhomocysteinemia impairs the relaxation induced by bradykinin in the isolated rat carotid. | Amino acids 20091001 |
The EP1 subtype of prostaglandin E2 receptor: role in keratinocyte differentiation and expression in non-melanoma skin cancer. | Prostaglandins, leukotrienes, and essential fatty acids 20091001 |
Regulation of ANP secretion from isolated atria by prostaglandins and cyclooxygenase-2. | Peptides 20090901 |
Ketamine inhibits the phagocytic responses of canine peripheral blood polymorphonuclear cells through the upregulation of prostaglandin E2 in peripheral blood mononuclear cells in vitro. | Research in veterinary science 20090801 |
Activation of prostaglandin E2 EP1 receptor increases arteriolar tone and blood pressure in mice with type 2 diabetes. | Cardiovascular research 20090701 |
Prostaglandin E2 released from activated microglia enhances astrocyte proliferation in vitro. | Toxicology and applied pharmacology 20090701 |
Prostaglandin E2 signaling through E prostanoid receptor 2 impairs proliferative response of double negative regulatory T cells. | International immunopharmacology 20090501 |
Developmental changes in the effects of prostaglandin E2 in the chicken ductus arteriosus. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20090201 |
Prostaglandin E2 and its cognate EP receptors control human adult articular cartilage homeostasis and are linked to the pathophysiology of osteoarthritis. | Arthritis and rheumatism 20090201 |
Effect of prostaglandin E2 on urokinase-type plasminogen activator production by human lung fibroblasts. | Scandinavian journal of clinical and laboratory investigation 20090101 |
Roles of cyclooxygenase-2 in microvascular endothelial cell proliferation induced by basic fibroblast growth factor. | Chinese medical journal 20081220 |
15d-PGJ2 upregulates synthesis of IL-8 in endothelial cells through induction of oxidative stress. | Antioxidants & redox signaling 20081201 |
Engagement of the EP2 prostanoid receptor closes the K+ channel KCa3.1 in human lung mast cells and attenuates their migration. | European journal of immunology 20080901 |
The effects of cyclooxygenase2-prostaglandinE2 pathway on Helicobacter pylori-induced urokinase-type plasminogen activator system in the gastric cancer cells. | Helicobacter 20080601 |
The role of prostaglandin E and thromboxane-prostanoid receptors in the response to prostaglandin E2 in the aorta of Wistar Kyoto rats and spontaneously hypertensive rats. | Cardiovascular research 20080401 |
Prostaglandin E2 glycerol ester, an endogenous COX-2 metabolite of 2-arachidonoylglycerol, induces hyperalgesia and modulates NFkappaB activity. | British journal of pharmacology 20080401 |
Prostaglandin E2 and F2alpha activate the FP receptor and up-regulate cyclooxygenase-2 expression via the cyclic AMP response element. | Molecular and cellular endocrinology 20080326 |
PTGER1 and PTGER2 receptors mediate regulation of progesterone synthesis and type 1 11beta-hydroxysteroid dehydrogenase activity by prostaglandin E2 in human granulosa lutein cells. | The Journal of endocrinology 20070901 |
Prostaglandin E2 enhances acetylcholine-induced, Ca2+-dependent ionic currents in swine tracheal mucous gland cells. | The Journal of pharmacology and experimental therapeutics 20070801 |
Prostaglandin E2 enhances the sensitizing effect of hyperthermia on pulmonary C-fibers in rats. | Respiratory physiology & neurobiology 20070615 |
Development and validation of a liquid chromatography/tandem mass spectrometry method for the determination of DMXAA in human and mouse plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601 |
TNF-alpha modulates hepatic Na+-K+ ATPase activity via PGE2 and EP2 receptors. | Prostaglandins & other lipid mediators 20070601 |
Functional characterization of the mechanisms underlying bradykinin-induced relaxation in the isolated rat carotid artery. | Life sciences 20070417 |
Iloprost-induced desensitization of the prostacyclin receptor in isolated rabbit lungs. | Respiratory research 20070101 |
Involvement of cyclooxygenase-2--prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells. | Digestive diseases and sciences 20061201 |
Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor. | American journal of physiology. Renal physiology 20060601 |
Identification of prostaglandin E2 receptor subtype 2 as a receptor activated by OxPAPC. | Circulation research 20060317 |
Early changes in prostaglandins precede bone formation in a rabbit model of heterotopic ossification. | Bone 20060301 |
Involvement of EP1 and EP2 receptors in the regulation of the Na,K-ATPase by prostaglandins in MDCK cells. | Prostaglandins & other lipid mediators 20060301 |
Role of periaqueductal grey prostaglandin receptors in formalin-induced hyperalgesia. | European journal of pharmacology 20060113 |
Prostaglandin E2 drives cyclooxygenase-2 expression via cyclic AMP response element activation in human pancreatic cancer cells. | Cancer biology & therapy 20051101 |
Lipopolysaccharide-induced changes in mesenteric afferent sensitivity of rat jejunum in vitro: role of prostaglandins. | American journal of physiology. Gastrointestinal and liver physiology 20050801 |
Sensitization of mesenteric afferents to chemical and mechanical stimuli following systemic bacterial lipopolysaccharide. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20050201 |
EP1- and EP3-receptors mediate prostaglandin E2-induced constriction of porcine large cerebral arteries. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20041201 |
Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs. | Osteoarthritis and cartilage 20041101 |
Prostacyclin release and receptor activation: differential control of human pulmonary venous and arterial tone. | British journal of pharmacology 20040601 |
Prostaglandin E2 regulates amyloid precursor protein expression via the EP2 receptor in cultured rat microglia. | Neuroscience letters 20040520 |
Identification in human airways smooth muscle cells of the prostanoid receptor and signalling pathway through which PGE2 inhibits the release of GM-CSF. | British journal of pharmacology 20040401 |
E-ring 8-isoprostanes inhibit ACh release from parasympathetic nerves innervating guinea-pig trachea through agonism of prostanoid receptors of the EP3-subtype. | British journal of pharmacology 20040201 |
Inhibition of human glioma cell growth by a PHS-2 inhibitor, NS398, and a prostaglandin E receptor subtype EP1-selective antagonist, SC51089. | Journal of neuro-oncology 20040201 |
Glutamate-mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytes. | The Journal of physiology 20031201 |
Effects of mechanical strain on the function of Gap junctions in osteocytes are mediated through the prostaglandin EP2 receptor. | The Journal of biological chemistry 20031031 |
Role of prostaglandin E2 receptors in migration of murine and human breast cancer cells. | Experimental cell research 20031001 |
Leukotriene D4-induced adhesion of Caco-2 cells is mediated by prostaglandin E2 and upregulation of alpha2beta1-integrin. | Experimental cell research 20031001 |
Modulation of guinea pig intrinsic cardiac neurons by prostaglandins. | American journal of physiology. Regulatory, integrative and comparative physiology 20030901 |
Effects of PGE2 in guinea pig colonic myenteric ganglia. | American journal of physiology. Gastrointestinal and liver physiology 20021201 |
Differential peristaltic motor effects of prostanoid (DP, EP, IP, TP) and leukotriene receptor agonists in the guinea-pig isolated small intestine. | British journal of pharmacology 20021201 |
PGD(2) modulates fibroblast-mediated native collagen gel contraction. | American journal of respiratory cell and molecular biology 20020901 |
AH6809 antagonizes non-small cell lung cancer prostaglandin receptors. | Lung cancer (Amsterdam, Netherlands) 20020401 |
Cloned human EP1 prostanoid receptor pharmacology characterized using radioligand binding techniques. | The Journal of pharmacy and pharmacology 20020401 |
Role of EP(1) and EP(4) PGE(2) subtype receptors in serum-induced 3T6 fibroblast cycle progression and proliferation. | American journal of physiology. Cell physiology 20020201 |
Trophic effects of the cyclooxygenase-2 product prostaglandin E(2) in cardiac myocytes. | Hypertension (Dallas, Tex. : 1979) 20020201 |
Prostanoid EP(1)- and TP-receptors involved in the contraction of human pulmonary veins. | British journal of pharmacology 20011201 |
Prostanoids stimulate K secretion and Cl secretion in guinea pig distal colon via distinct pathways. | American journal of physiology. Gastrointestinal and liver physiology 20011001 |
Human granulosa-lutein cells express functional EP1 and EP2 prostaglandin receptors. | Biochemical and biophysical research communications 20010803 |
Characterization of PGE2 receptors in fetal and newborn lamb ductus arteriosus. | American journal of physiology. Heart and circulatory physiology 20010501 |
EP(4) receptors mediate prostaglandin E(2)-stimulated glycosaminoglycan synthesis in human cervical fibroblasts in culture. | Molecular human reproduction 20010401 |
Role of PGE(2) in protease-activated receptor-1, -2 and -4 mediated relaxation in the mouse isolated trachea. | British journal of pharmacology 20010101 |
The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs. | Biochimica et biophysica acta 20000117 |
Molecular cloning and characterization of the four rat prostaglandin E2 prostanoid receptor subtypes. | European journal of pharmacology 19971211 |
Characterization of the prostanoid receptor(s) on human blood monocytes at which prostaglandin E2 inhibits lipopolysaccharide-induced tumour necrosis factor-alpha generation. | British journal of pharmacology 19970901 |
Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells. | British journal of pharmacology 19970901 |
6-Isopropoxy-9-oxoxanthene-2-carboxylic acid (AH 6809), a human EP2 receptor antagonist. | Biochemical pharmacology 19951109 |
Nociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2 alpha to conscious mice. | Brain research 19900226 |
Selective inhibition of prostaglandin E2 receptors EP2 and EP4 induces apoptosis of human endometriotic cells through suppression of ERK1/2, AKT, NFkappaB, and beta-catenin pathways and activation of intrinsic apoptotic mechanisms. | Molecular endocrinology (Baltimore, Md.) |
Estrogen receptor-related receptor alpha mediates up-regulation of aromatase expression by prostaglandin E2 in prostate stromal cells. | Molecular endocrinology (Baltimore, Md.) |