1-((2-(Diethylamino)ethyl)amino)-4-(hydroxymethyl)-9H-thioxanthen-9-one
Title | Journal |
---|---|
Screening of a chemical library reveals novel PXR-activating pharmacologic compounds. | Toxicology letters 20150105 |
Using functional signatures to identify repositioned drugs for breast, myelogenous leukemia and prostate cancer. | PLoS computational biology 20120201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Evaluation of a 25-year-program for the control of schistosomiasis mansoni in an endemic area in Brazil. | PLoS neglected tropical diseases 20110301 |
Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding. | PloS one 20110101 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
RNA interference in Schistosoma mansoni schistosomula: selectivity, sensitivity and operation for larger-scale screening. | PLoS neglected tropical diseases 20101001 |
Discovery of potent small-molecule inhibitors of multidrug-resistant Plasmodium falciparum using a novel miniaturized high-throughput luciferase-based assay. | Antimicrobial agents and chemotherapy 20100901 |
Identification of novel p53 pathway activating small-molecule compounds reveals unexpected similarities with known therapeutic agents. | PloS one 20100101 |
Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni. | PLoS neglected tropical diseases 20090801 |
Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening. | PLoS neglected tropical diseases 20090701 |
Mefloquine--an aminoalcohol with promising antischistosomal properties in mice. | PLoS neglected tropical diseases 20090101 |
The NIH-NIAID schistosomiasis resource center. | PLoS neglected tropical diseases 20080701 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
Long-term hepatocellular effects of hycanthone and of two other anti-Schistosomal drugs in mice infected with Schistosoma mansoni. | The Journal of pharmacology and experimental therapeutics 19760601 |