Home Other Building Blocks Z-Val-dl-asp-fluoromethylketone

Z-Val-dl-asp-fluoromethylketone

CAS No.:
223568-55-6
Catalog Number:
AG00BGLA
Molecular Formula:
C18H23FN2O6
Molecular Weight:
382.3834
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
97%
1 week
United States
$240
- +
5mg
97%
1 week
United States
$423
- +
10mg
97%
1 week
United States
$640
- +
50mg
97%
1 week
United States
$1707
- +
100mg
97%
1 week
United States
$2723
- +
Product Description
Catalog Number:
AG00BGLA
Chemical Name:
Z-Val-dl-asp-fluoromethylketone
CAS Number:
223568-55-6
Molecular Formula:
C18H23FN2O6
Molecular Weight:
382.3834
MDL Number:
MFCD08457673
IUPAC Name:
(3S)-5-fluoro-3-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]-4-oxopentanoic acid
InChI:
InChI=1S/C18H23FN2O6/c1-11(2)16(17(25)20-13(8-15(23)24)14(22)9-19)21-18(26)27-10-12-6-4-3-5-7-12/h3-7,11,13,16H,8-10H2,1-2H3,(H,20,25)(H,21,26)(H,23,24)/t13-,16-/m0/s1
InChI Key:
LYBWGROBJJXCJJ-BBRMVZONSA-N
SMILES:
FCC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C(C)C)NC(=O)OCc1ccccc1
Properties
Complexity:
534  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
382.154g/mol
Formal Charge:
0
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
382.388g/mol
Monoisotopic Mass:
382.154g/mol
Rotatable Bond Count:
11  
Topological Polar Surface Area:
122A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.8  
Literature
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Peptidomimetic GnRH antagonist AEZS-115 inhibits the growth of ovarian and endometrial cancer cells. Anticancer research 20120501
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Caspase inhibitor therapy synergizes with costimulation blockade to promote indefinite islet allograft survival. Diabetes 20100601
Caspase-dependent apoptosis of ON bipolar cells in the goldfish marginal retina. Neuroreport 20091007
In vivo administration of calpeptin attenuates calpain activation and cardiomyocyte loss in pressure-overloaded feline myocardium. American journal of physiology. Heart and circulatory physiology 20080701
The caspase selective inhibitor EP1013 augments human islet graft function and longevity in marginal mass islet transplantation in mice. Diabetes 20080601
Release of arachidonic acid induced by tumor necrosis factor-alpha in the presence of caspase inhibition: evidence for a cytosolic phospholipase A2alpha-independent pathway. Biochemical pharmacology 20080315
Caspase-independent autophagic cytotoxicity in etoposide-treated CaSki cervical carcinoma cells. DNA and cell biology 20071001
Calpain-dependent calpastatin cleavage regulates caspase-3 activation during apoptosis of Jurkat T cells induced by Entamoeba histolytica. International journal for parasitology 20070901
CIL-102 interacts with microtubule polymerization and causes mitotic arrest following apoptosis in the human prostate cancer PC-3 cell line. The Journal of biological chemistry 20050128
MX1013, a dipeptide caspase inhibitor with potent in vivo antiapoptotic activity. British journal of pharmacology 20030901
Properties