Home Other Building Blocks sophoflavescenol

sophoflavescenol

CAS No.:
216450-65-6
Catalog Number:
AG00BFSB
Molecular Formula:
C21H20O6
Molecular Weight:
368.3799
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
98%
1 week
United States
$423
- +
5mg
98%
1 week
United States
$1157
- +
Product Description
Catalog Number:
AG00BFSB
Chemical Name:
sophoflavescenol
CAS Number:
216450-65-6
Molecular Formula:
C21H20O6
Molecular Weight:
368.3799
MDL Number:
MFCD30534403
IUPAC Name:
3,7-dihydroxy-2-(4-hydroxyphenyl)-5-methoxy-8-(3-methylbut-2-enyl)chromen-4-one
InChI:
InChI=1S/C21H20O6/c1-11(2)4-9-14-15(23)10-16(26-3)17-18(24)19(25)20(27-21(14)17)12-5-7-13(22)8-6-12/h4-8,10,22-23,25H,9H2,1-3H3
InChI Key:
VMLJAWUWVVHRNG-UHFFFAOYSA-N
SMILES:
COc1cc(O)c(c2c1c(=O)c(O)c(o2)c1ccc(cc1)O)CC=C(C)C
Properties
Complexity:
612  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
368.126g/mol
Formal Charge:
0
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
368.385g/mol
Monoisotopic Mass:
368.126g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
96.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.2  
Literature
Title Journal
Kinetics and molecular docking studies of kaempferol and its prenylated derivatives as aldose reductase inhibitors. Chemico-biological interactions 20120530
Anti-tumorigenic activity of sophoflavescenol against Lewis lung carcinoma in vitro and in vivo. Archives of pharmacal research 20111201
Antidiabetic complications and anti-Alzheimer activities of sophoflavescenol, a prenylated flavonol from Sophora flavescens, and its structure-activity relationship. Phytotherapy research : PTR 20110501
8-Prenylkaempferol Suppresses Influenza A Virus-Induced RANTES Production in A549 Cells via Blocking PI3K-Mediated Transcriptional Activation of NF-κB and IRF3. Evidence-based complementary and alternative medicine : eCAM 20110101
2-Phenylquinazolin-4(3H)-one, a class of potent PDE5 inhibitors with high selectivity versus PDE6. Bioorganic & medicinal chemistry letters 20090515
Prenylated flavonoids as tyrosinase inhibitors. Archives of pharmacal research 20041101
A prenylated flavonol, sophoflavescenol: a potent and selective inhibitor of cGMP phosphodiesterase 5. Bioorganic & medicinal chemistry letters 20020902
Properties