Tetrasodium (2S)-2-((((7S,8S)-3-carboxylato-7-(2-carboxylatoethyl)-13-ethenyl-18-ethyl-2,8,12,17-tetramethyl-7,8-dihydroporphyrin-5-yl)acetyl)amino)butanedioate
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Preclinical in vivo evaluation of NPe6-mediated photodynamic therapy on normal vasculature. | Lasers in surgery and medicine 20120201 |
Tissue damage in the canine normal esophagus by photoactivation with talaporfin sodium (laserphyrin): a preclinical study. | PloS one 20120101 |
Myocardial electrical conduction block induced by photosensitization reaction in exposed porcine hearts in vivo. | Lasers in surgery and medicine 20111201 |
Inhibition of endocytic processes by photodynamic therapy. | Lasers in surgery and medicine 20110901 |
Molecular determinants of photodynamic therapy for lung cancers. | Lasers in surgery and medicine 20110901 |
New aspects of photodynamic therapy for central type early stage lung cancer. | Lasers in surgery and medicine 20110901 |
Advantages of laserphyrin compared with photofrin in photodynamic therapy for bile duct carcinoma. | Journal of hepato-biliary-pancreatic sciences 20110701 |
Cell death via mitochondrial apoptotic pathway due to activation of Bax by lysosomal photodamage. | Free radical biology & medicine 20110701 |
Sonodynamic cancer therapy: a non-invasive and repeatable approach using low-intensity ultrasound with a sonosensitizer. | Anticancer research 20110701 |
Effects of endosomal photodamage on membrane recycling and endocytosis. | Photochemistry and photobiology 20110501 |
Determination of the tumor tissue optical properties during and after photodynamic therapy using inverse Monte Carlo method and double integrating sphere between 350 and 1000 nm. | Journal of biomedical optics 20110501 |
Effects of photodynamic therapy on the endocytic pathway. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110430 |
Characterization of cutaneous photosensitivity in healthy volunteers receiving talaporfin sodium. | Photodermatology, photoimmunology & photomedicine 20110401 |
Sonodynamically-induced antitumor effect of mono-l-aspartyl chlorin e6 (NPe6). | Anticancer research 20110201 |
Nonesterified cholesterol content of lysosomes modulates susceptibility to oxidant-induced permeabilization. | Free radical biology & medicine 20110115 |
Photosensitization reaction-induced acute electrophysiological cell response of rat myocardial cells in short loading periods of talaporfin sodium or porfimer sodium. | Photochemistry and photobiology 20110101 |
Evaluation of oxygen consumption of culture medium and in vitro photodynamic effect of talaporfin sodium in lung tumor cells. | Photomedicine and laser surgery 20100601 |
Photodynamic therapy induces microRNA-210 and -296 expression in HeLa cells. | Journal of biophotonics 20100601 |
Novel photodynamic therapy against biliary tract carcinoma using mono-L: -aspartyl chlorine e6: basic evaluation for its feasibility and efficacy. | Journal of hepato-biliary-pancreatic sciences 20100501 |
Outcome of photodynamic therapy using NPe6 for bronchogenic carcinomas in central airways >1.0 cm in diameter. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100401 |
Breast cancer resistant protein (BCRP) is a molecular determinant of the outcome of photodynamic therapy (PDT) for centrally located early lung cancer. | Lung cancer (Amsterdam, Netherlands) 20100201 |
The myocardial electrical blockade induced by photosensitization reaction. | IEEE transactions on bio-medical engineering 20100201 |
Talaporfin-mediated photodynamic therapy for peritoneal metastasis of gastric cancer in an in vivo mouse model: drug distribution and efficacy studies. | International journal of oncology 20100201 |
Management of multiple primary lung cancer in patients with centrally located early cancer lesions. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20100101 |
Talaporfin sodium. | Expert opinion on pharmacotherapy 20100101 |
Histological responses of cutaneous vascular lesions following photodynamic therapy with talaporfin sodium: a chicken comb model. | The Keio journal of medicine 20090901 |
Fluorescence diagnosis of lymph node metastasis of lung cancer in a mouse model. | Oncology reports 20090701 |
[Clinical photodynamic diagnosis and therapy efficiency in oropharyngeal cancer]. | Nihon Jibiinkoka Gakkai kaiho 20090501 |
The optimization of fluorescence imaging of brain tumor tissue differentiated from brain edema--in vivo kinetic study of 5-aminolevulinic acid and talaporfin sodium. | Photodiagnosis and photodynamic therapy 20090301 |
Amelioration of airway stenosis in rabbit models by photodynamic therapy with talaporfin sodium (NPe6). | Photochemistry and photobiology 20090101 |
Therapeutic effects of a new photosensitizer for photodynamic therapy of early head and neck cancer in relation to tissue concentration. | Auris, nasus, larynx 20081201 |
Time-dependent interactions of the two porphyrinic compounds chlorin e6 and mono-L-aspartyl-chlorin e6 with phospholipid vesicles probed by NMR spectroscopy. | Langmuir : the ACS journal of surfaces and colloids 20081104 |
Differential effects of photodynamic therapy on morphologically distinct tumor cells derived from a single precursor cell. | Cancer letters 20080918 |
Photodynamic therapy of C6-implanted glioma cells in the rat brain employing second-generation photosensitizer talaporfin sodium. | Photodiagnosis and photodynamic therapy 20080901 |
Uptake and retention of the photosensitizer mono-L-asparthyl chlorine e6 in experimental malignant glioma. | Lasers in medical science 20080701 |
Photodynamic therapy using talaporfin sodium for synovial membrane from rheumatoid arthritis patients and collagen-induced arthritis rats. | Clinical rheumatology 20080601 |
In vivo confocal fluorescence imaging of the intratumor distribution of the photosensitizer mono-L-aspartylchlorin-e6. | Neoplasia (New York, N.Y.) 20080501 |
High expression of GADD-45alpha and VEGF induced tumor recurrence via upregulation of IL-2 after photodynamic therapy using NPe6. | International journal of oncology 20080201 |
Sonodynamically-induced apoptosis, necrosis, and active oxygen generation by mono-l-aspartyl chlorin e6. | Cancer science 20080101 |
Bid is required in NPe6-PDT-induced apoptosis. | Photochemistry and photobiology 20080101 |
Photosensitization reaction-induced electrical blockade in myocardial tissue. | Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20080101 |
Photodynamic therapy for lung cancers based on novel photodynamic diagnosis using talaporfin sodium (NPe6) and autofluorescence bronchoscopy. | Lung cancer (Amsterdam, Netherlands) 20071201 |
A Phase II safety and effect on time to tumor progression study of intratumoral light infusion technology using talaporfin sodium in patients with metastatic colorectal cancer. | Journal of surgical oncology 20071101 |
Expression of vascular endothelial growth factor by photodynamic therapy with mono-L-aspartyl chlorin e6 (NPe6) in oral squamous cell carcinoma. | Oral oncology 20070701 |
Survivin, a member of the inhibitor of apoptosis family, is induced by photodynamic therapy and is a target for improving treatment response. | Cancer research 20070515 |
Index-of-refraction-dependent subcellular light scattering observed with organelle-specific dyes. | Journal of biomedical optics 20070101 |
Intraocular biodistribution of mono-L-aspartyl chlorin e6 in a primate choroidal neovascularization model. | Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20070101 |
Mono-(L)-aspartylchlorin-e6. | Photochemistry and photobiology 20070101 |
In vitro behavior of Porfimer sodium and Talaporfin sodium with high intensity pulsed irradiation. | Lasers in medical science 20061201 |
Basic and clinical research on photodynamic therapy at Tokyo Medical University Hospital. | Lasers in surgery and medicine 20060601 |
Photodynamic therapy with mono-L-aspartyl chlorin e6 can cause necrosis of squamous cell carcinoma of tongue: experimental study on an animal model of nude mouse. | Oral oncology 20060101 |
Tumor viability using real-time spectral images. | Surgery today 20060101 |
Sphingomyelins suppress the targeted disruption of lysosomes/endosomes by the photosensitizer NPe6 during photodynamic therapy. | The Biochemical journal 20051201 |
Long-term inhibition of intimal hyperplasia using vascular photodynamic therapy in balloon-injured carotid arteries. | Medical molecular morphology 20051201 |
Laser photocoagulation and, to a lesser extent, photodynamic therapy target and enhance adenovirus vector-mediated gene transfer in the rat retina. | Investigative ophthalmology & visual science 20051001 |
Pharmacokinetics and clinical effects of mono-L-aspartyl chlorin e6 (NPe6) photodynamic therapy in adult patients with primary or secondary cancer of the skin and mucosal surfaces. | Photodermatology, photoimmunology & photomedicine 20050401 |
Killing tumor cells: the effect of photodynamic therapy using mono-L-aspartyl chlorine and NS-398. | American journal of surgery 20050301 |
Effects of photodynamic therapy using a fractionated dosing of mono-L-aspartyl chlorin e6 in a murine tumor. | Journal of photochemistry and photobiology. B, Biology 20050201 |
Detection of photodynamic therapy-induced early apoptosis in human salivary gland tumor cells in vitro and in a mouse tumor model. | Oral oncology 20040901 |
[Development of a novel photosensitizer, talaporfin sodium, for the photodynamic therapy (PDT)]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040601 |
Photodynamic therapy upregulates expression of Mac-1 and generation of leukotriene B(4) by human polymorphonuclear leukocytes. | Oral oncology 20040501 |
Differential susceptibilities of murine hepatoma 1c1c7 and Tao cells to the lysosomal photosensitizer NPe6: influence of aryl hydrocarbon receptor on lysosomal fragility and protease contents. | Molecular pharmacology 20040401 |
CHOP activation by photodynamic therapy increases treatment induced photosensitization. | Lasers in surgery and medicine 20040101 |
Phase II clinical study of photodynamic therapy using mono-L-aspartyl chlorin e6 and diode laser for early superficial squamous cell carcinoma of the lung. | Lung cancer (Amsterdam, Netherlands) 20031001 |
Pilot study of topical delivery of mono-L-aspartyl chlorin e6 (NPe6): implication of topical NPe6-photodynamic therapy. | Journal of pharmacological sciences 20031001 |
In vitro photodynamic diagnosis of atherosclerotic wall changes with the use of mono-l-aspartyl chlorin e6. A preliminary report. | Kardiologia polska 20031001 |
Talaporfin sodium. LS 11, ME 2906, mono-L-aspartyl chlorine e6, NP e6, NPE 6, taporfin sodium. | Drugs in R&D 20030101 |
Photodynamic therapy of intestinal tumors with mono-L-aspartyl chlorin e6 (NPe6): a basic study. | Anticancer research 20030101 |
Release of cytochrome c and activation of pro-caspase-9 following lysosomal photodamage involves Bid cleavage. | Cell death and differentiation 20020901 |
Phase-resolved fluorescence study of mono-L-aspartyl chlorin E6. | Journal of photochemistry and photobiology. B, Biology 20020501 |
Morphologic evaluation of the antitumor activity of photodynamic therapy (PDT) using mono-L-aspartyl chlorin e6 (NPe6) against uterine cervical carcinoma cell lines. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20020101 |
New technology for deep light distribution in tissue for phototherapy. | Cancer journal (Sudbury, Mass.) 20020101 |
Increased cytotoxic effects of photodynamic therapy in IL-6 gene transfected cells via enhanced apoptosis. | International journal of cancer 20010815 |
Endovascular photodynamic therapy using mono-L-aspartyl-chlorin e6 to inhibit Intimal hyperplasia in balloon-injured rabbit arteries. | Lasers in surgery and medicine 20010101 |
Toxicity of the photosensitizer NPe6 following intravitreal injection. | Ophthalmic surgery and lasers 20010101 |
Retreatment effect of NPe6 photodynamic therapy on the normal primate macula. | Retina (Philadelphia, Pa.) 20010101 |
Photodynamic therapy of experimental choroidal neovascularization with a hydrophilic photosensitizer: mono-L-aspartyl chlorin e6. | Retina (Philadelphia, Pa.) 20010101 |