2-(4-((2,5-Difluorobenzyl)oxy)phenoxy)-5-ethoxyaniline
| Title | Journal |
|---|---|
| Axonal protection achieved by blockade of sodium/calcium exchange in a new model of ischemia in vivo. | Neuropharmacology 20120901 |
| Revisiting the ionic mechanisms of early afterdepolarizations in cardiomyocytes: predominant by Ca waves or Ca currents? | American journal of physiology. Heart and circulatory physiology 20120415 |
| Molecular and functional characterization of the human platelet Na(+) /Ca(2+) exchangers. | British journal of pharmacology 20120201 |
| SEA0400, a specific Na+/Ca2+ exchange inhibitor, prevents dopaminergic neurotoxicity in an MPTP mouse model of Parkinson's disease. | Neuropharmacology 20111201 |
| The specific Na(+)/Ca(2+) exchange inhibitor SEA0400 prevents nitric oxide-induced cytotoxicity in SH-SY5Y cells. | Neurochemistry international 20110801 |
| Dual inhibition of sodium-mediated proton and calcium efflux triggers non-apoptotic cell death in malignant gliomas. | Brain research 20101202 |
| KB-R7943 inhibits Na+-dependent Mg2+ efflux in rat ventricular myocytes. | The journal of physiological sciences : JPS 20101101 |
| Pathophysiological remodeling of mouse cardiac myocytes expressing dominant negative mutant of neuron restrictive silencing factor. | Circulation journal : official journal of the Japanese Circulation Society 20101101 |
| Knockout of Na+/Ca2+ exchanger in smooth muscle attenuates vasoconstriction and L-type Ca2+ channel current and lowers blood pressure. | American journal of physiology. Heart and circulatory physiology 20100501 |
| I(Ks) restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation. | Journal of molecular and cellular cardiology 20100101 |
| Cerebral ischemia elicits aberration in myocardium contractile function and intracellular calcium handling. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101 |
| Assessing manganese efflux using SEA0400 and cardiac T1-mapping manganese-enhanced MRI in a murine model. | NMR in biomedicine 20091001 |
| Involvement of protein kinase C in the regulation of Na+/Ca2+ exchanger in bovine adrenal chromaffin cells. | Clinical and experimental pharmacology & physiology 20090701 |
| Role of Na+/Ca2+ exchanger-mediated Ca2+ entry in pressure-induced myogenic constriction in rat posterior cerebral arteries. | Journal of pharmacological sciences 20090601 |
| Involvement of the Na(+)/Ca(2+) exchanger in the automaticity of guinea-pig pulmonary vein myocardium as revealed by SEA0400. | Journal of pharmacological sciences 20090501 |
| A Na+/Ca2+ exchanger isoform, NCX1, is involved in retinal cell death after N-methyl-D-aspartate injection and ischemia-reperfusion. | Journal of neuroscience research 20090301 |
| Potential therapeutic effects of Na+/Ca2+ exchanger inhibition in cardiac diseases. | Current medicinal chemistry 20090101 |
| Inhibition of the Na+/Ca2+ exchanger suppresses torsades de pointes in an intact heart model of long QT syndrome-2 and long QT syndrome-3. | Heart rhythm 20081001 |
| Antiarrhythmic benefits of targeting the Na+/Ca2+ exchanger. | Heart rhythm 20081001 |
| Burst emergence of intracellular Ca2+ waves evokes arrhythmogenic oscillatory depolarization via the Na+-Ca2+ exchanger: simultaneous confocal recording of membrane potential and intracellular Ca2+ in the heart. | Circulation research 20080829 |
| SEA0400 fails to alter the magnitude of intracellular Ca2+ transients and contractions in Langendorff-perfused guinea pig heart. | Naunyn-Schmiedeberg's archives of pharmacology 20080701 |
| Pharmacological inhibition of na/ca exchange results in increased cellular Ca2+ load attributable to the predominance of forward mode block. | Circulation research 20080606 |
| The ins and outs of calcium in heart failure. | Circulation research 20080606 |
| The Na+/Ca2+ exchange blocker SEA0400 fails to enhance cytosolic Ca2+ transient and contractility in canine ventricular cardiomyocytes. | Cardiovascular research 20080601 |
| Na(+)/Ca(2+) exchanger inhibition exerts a positive inotropic effect in the rat heart, but fails to influence the contractility of the rabbit heart. | British journal of pharmacology 20080501 |
| Intracellular mechanisms and receptor types for endothelin-1-induced positive and negative inotropy in mouse ventricular myocardium. | Naunyn-Schmiedeberg's archives of pharmacology 20080201 |
| Effect of partial blockade of the Na(+)/Ca(2+)-exchanger on Ca(2+) handling in isolated rat ventricular myocytes. | European journal of pharmacology 20071208 |
| S1P1-selective agonist SEW2871 exacerbates reperfusion arrhythmias. | Journal of cardiovascular pharmacology 20071201 |
| Mechanisms of endothelin-1-induced decrease in contractility in adult mouse ventricular myocytes. | British journal of pharmacology 20071001 |
| Negative inotropic effects of endothelin-1 in mouse cardiomyocytes: evidence of a role for Na+-Ca2+ exchange. | British journal of pharmacology 20071001 |
| [Molecular pharmacologic approaches to functional analysis of new biological target molecules for drug discovery]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071001 |
| Preservation of mitochondrial function may contribute to cardioprotective effects of Na+/Ca2+ exchanger inhibitors in ischaemic/reperfused rat hearts. | British journal of pharmacology 20070801 |
| Monensin causes transient calcium ion influx into mouse splenic lymphocytes in a sodium ion-independent fashion. | European journal of pharmacology 20070430 |
| Interaction between Na+/K+-pump and Na+/Ca2+-exchanger modulates intercellular communication. | Circulation research 20070413 |
| [Na+/Ca2+ exchanger (NCX1) and cardiovascular disease]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20070401 |
| Involvement of Na+-Ca2+ exchanger in cAMP-mediated relaxation in mice aorta: evaluation using transgenic mice. | British journal of pharmacology 20070201 |
| Involvement of the Na+/Ca2+ exchanger in ouabain-induced inotropy and arrhythmogenesis in guinea-pig myocardium as revealed by SEA0400. | Journal of pharmacological sciences 20070201 |
| SEA0400, a novel Na+/Ca2+ exchanger inhibitor, reduces calcium overload induced by ischemia and reperfusion in mouse ventricular myocytes. | Physiological research 20070101 |
| Anesthetic preconditioning enhances Ca2+ handling and mechanical and metabolic function elicited by Na+-Ca2+ exchange inhibition in isolated hearts. | Anesthesiology 20060901 |
| Inhibition by SEA0400, a selective inhibitor of Na+/Ca2+ exchanger, of Na+ -dependent Ca2+ uptake and catecholamine release in bovine adrenal chromaffin cells. | Journal of pharmacological sciences 20060901 |
| Reduction by SEA0400 of myocardial ischemia-induced cytoplasmic and mitochondrial Ca2+ overload. | European journal of pharmacology 20060814 |
| Quantitative fluorescence measurement of cardiac Na+/Ca2+ exchanger inhibition by kinetic analysis in stably transfected HEK293 cells. | Journal of pharmacological sciences 20060801 |
| Cardioprotection via activation of protein kinase C-delta depends on modulation of the reverse mode of the Na+/Ca2+ exchanger. | Circulation 20060704 |
| Hypertension, Na+/Ca2+ exchanger, and Na+, K+-ATPase. | Kidney international 20060601 |
| Sodium-dependent recovery of ionised magnesium concentration following magnesium load in rat heart myocytes. | Pflugers Archiv : European journal of physiology 20060201 |
| A selective inhibitor of Na+/Ca2+ exchanger, SEA0400, preserves cardiac function and high-energy phosphates against ischemia/reperfusion injury. | Journal of cardiovascular pharmacology 20060201 |
| [Na+/Ca2+ exchanger(NCX1) and salt-sensitive hypertension]. | Nihon rinsho. Japanese journal of clinical medicine 20060101 |
| Sodium calcium exchange as a target for antiarrhythmic therapy. | Handbook of experimental pharmacology 20060101 |
| Salt-sensitive hypertension, Na+/Ca2+ exchanger, and vascular smooth muscle. | Trends in cardiovascular medicine 20051101 |
| Effects of SEA0400 and KB-R7943 on Na+/Ca2+ exchange current and L-type Ca2+ current in canine ventricular cardiomyocytes. | Naunyn-Schmiedeberg's archives of pharmacology 20050701 |
| Cardioprotection without cardiosuppression by SEA0400, a novel inhibitor of Na+-Ca2+ exchanger, during ischemia and reperfusion in guinea-pig myocardium. | Life sciences 20050603 |
| SEA-0400, a potent inhibitor of the Na+/Ca2+ exchanger, as a tool to study exchanger ionic and metabolic regulation. | American journal of physiology. Cell physiology 20050601 |
| Unique excitation-contraction characteristics of mouse myocardium as revealed by SEA0400, a specific inhibitor of Na+-Ca2+ exchanger. | Naunyn-Schmiedeberg's archives of pharmacology 20050601 |
| Therapeutic potential of novel Na+-Ca2+ exchange inhibitors in attenuating ischemia-reperfusion injury. | The Canadian journal of cardiology 20050501 |
| SEA0400, a specific inhibitor of the Na+-Ca2+ exchanger, attenuates sodium nitroprusside-induced apoptosis in cultured rat microglia. | British journal of pharmacology 20050301 |
| Functional proteins involved in regulation of intracellular Ca(2+) for drug development: pharmacology of SEA0400, a specific inhibitor of the Na(+)-Ca(2+) exchanger. | Journal of pharmacological sciences 20050301 |
| Effects of SEA0400, a Na+/Ca2+ exchange inhibitor, on ventricular arrhythmias in the in vivo dogs. | European journal of pharmacology 20050104 |
| Selective inhibition of sodium-calcium exchanger by SEA-0400 decreases early and delayed after depolarization in canine heart. | British journal of pharmacology 20041201 |
| Effects of SEA0400, a novel inhibitor of the Na+/Ca2+ exchanger, on myocardial stunning in anesthetized dogs. | European journal of pharmacology 20041128 |
| Inhibitory profile of SEA0400 [2-[4-[(2,5-difluorophenyl)methoxy]phenoxy]-5-ethoxyaniline] assessed on the cardiac Na+-Ca2+ exchanger, NCX1.1. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Salt-sensitive hypertension is triggered by Ca2+ entry via Na+/Ca2+ exchanger type-1 in vascular smooth muscle. | Nature medicine 20041101 |
| Hypertension with a grain of salt. | Nature medicine 20041101 |
| Forefront of Na+/Ca2+ exchanger studies: molecular pharmacology of Na+/Ca2+ exchange inhibitors. | Journal of pharmacological sciences 20040901 |
| Functional role of the Na+/H+ exchanger in the regulation of cerebral arteriolar tone in rats. | Journal of neurosurgery 20040801 |
| Effects of sodium-calcium exchange inhibitors, KB-R7943 and SEA0400, on aconitine-induced arrhythmias in guinea pigs in vivo, in vitro, and in computer simulation studies. | The Journal of pharmacology and experimental therapeutics 20040701 |
| Na+/Ca2+ exchange inhibitors: potential drugs to mitigate the severity of ischemic injury. | Molecular pharmacology 20040701 |
| The potential of Na+/Ca2+ exchange blockers in the treatment of cardiac disease. | Expert opinion on investigational drugs 20040601 |
| Cardioprotective effect of SEA0400, a selective inhibitor of the Na(+)/Ca(2+) exchanger, on myocardial ischemia-reperfusion injury in rats. | Journal of pharmacological sciences 20040601 |
| The selective Na+-Ca2+ exchange inhibitor attenuates brain edema after radiofrequency lesion in rats. | European journal of pharmacology 20040412 |
| Development and application of Na+/Ca2+ exchange inhibitors. | Molecular and cellular biochemistry 20040401 |
| Effects of SEA0400 on mutant NCX1.1 Na+-Ca2+ exchangers with altered ionic regulation. | Molecular pharmacology 20040301 |
| Molecular determinants of Na+/Ca2+ exchange (NCX1) inhibition by SEA0400. | The Journal of biological chemistry 20040227 |
| SEA0400: a novel sodium-calcium exchange inhibitor with cardioprotective properties. | Cardiovascular drug reviews 20040101 |
| Discovery of a novel potent Na+/Ca2+ exchanger inhibitor: design, synthesis and structure-activity relationships of 3,4-dihydro-2(1H)-quinazolinone derivatives. | Bioorganic & medicinal chemistry letters 20031020 |
| A novel and selective Na+/Ca2+ exchange inhibitor, SEA0400, improves ischemia/reperfusion-induced renal injury. | European journal of pharmacology 20031008 |
| Differing cardioprotective efficacy of the Na+/Ca2+ exchanger inhibitors SEA0400 and KB-R7943. | American journal of physiology. Heart and circulatory physiology 20030301 |
| Protective effects of SEA0400, a novel and selective inhibitor of the Na+/Ca2+ exchanger, on myocardial ischemia-reperfusion injuries. | European journal of pharmacology 20030101 |
| [Functional analysis of Na+/Ca2+ exchanger using novel drugs and genetically engineered mice]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021101 |
| Knockout mice for pharmacological screening: testing the specificity of Na+-Ca2+ exchange inhibitors. | Circulation research 20020726 |
| Effect of SEA0400, a novel inhibitor of sodium-calcium exchanger, on myocardial ionic currents. | British journal of pharmacology 20020301 |
| SEA0400, a novel and selective inhibitor of the Na+-Ca2+ exchanger, attenuates reperfusion injury in the in vitro and in vivo cerebral ischemic models. | The Journal of pharmacology and experimental therapeutics 20010701 |
| Order and disorder at hospital meetings. | Dimensions in health service 19751201 |