BX471
| Title | Journal |
|---|---|
| Chemokine receptor antagonists. | Journal of medicinal chemistry 20121126 |
| Exploring a model of a chemokine receptor/ligand complex in an explicit membrane environment by molecular dynamics simulation: the human CCR1 receptor. | Journal of chemical information and modeling 20111024 |
| The chemokine, CCL3, and its receptor, CCR1, mediate thoracic radiation-induced pulmonary fibrosis. | American journal of respiratory cell and molecular biology 20110701 |
| Why CCR2 and CCR5 blockade failed and why CCR1 blockade might still be effective in the treatment of rheumatoid arthritis. | PloS one 20110101 |
| No significant effect of orally administered chemokine receptor 1 antagonist on intercellular adhesion molecule-3 expression in relapsing--remitting multiple sclerosis patients. | Multiple sclerosis (Houndmills, Basingstoke, England) 20100301 |
| Fibrogenesis in kidney transplantation: potential targets for prevention and therapy. | Transplantation 20091127 |
| Assessment of QT(c)-prolonging potential of BX471 in healthy volunteers. A 'thorough QT study' following ICH E14 using various QT(c) correction methods. | British journal of clinical pharmacology 20090901 |
| Novel pyrrolidine ureas as C-C chemokine receptor 1 (CCR1) antagonists. | Journal of medicinal chemistry 20090312 |
| Chemokine receptor CCR1 regulates inflammatory cell infiltration after renal ischemia-reperfusion injury. | Journal of immunology (Baltimore, Md. : 1950) 20081215 |
| Leukocytes induce epithelial to mesenchymal transition after unilateral ureteral obstruction in neonatal mice. | The American journal of pathology 20070901 |
| Structure-activity relationships of novel, highly potent, selective, and orally active CCR1 antagonists. | Bioorganic & medicinal chemistry letters 20070615 |
| Treatment with BX471, a CC chemokine receptor 1 antagonist, attenuates systemic inflammatory response during sepsis. | American journal of physiology. Gastrointestinal and liver physiology 20070401 |
| Beneficial effects of CCR1 blockade on the progression of chronic renal allograft damage. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301 |
| Treatment with BX471, a nonpeptide CCR1 antagonist, protects mice against acute pancreatitis-associated lung injury by modulating neutrophil recruitment. | Pancreas 20070301 |
| Development of a multiple unit pellet formulation for a weakly basic drug. | Drug development and industrial pharmacy 20070301 |
| Blockade of chemokine signaling in patients with multiple sclerosis. | Neurology 20061128 |
| Predictions of CCR1 chemokine receptor structure and BX 471 antagonist binding followed by experimental validation. | The Journal of biological chemistry 20060915 |
| Effects of formulation and process variables on the release of a weakly basic drug from single unit extended release formulations. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060101 |
| Role of CCR1 and CCR5 in homing and growth of multiple myeloma and in the development of osteolytic lesions: a study in the 5TMM model. | Clinical & experimental metastasis 20060101 |
| Development of a single unit extended release formulation for ZK 811 752, a weakly basic drug. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050901 |
| BX471: a CCR1 antagonist with anti-inflammatory activity in man. | Mini reviews in medicinal chemistry 20050901 |
| Development of a multi particulate extended release formulation for ZK 811 752, a weakly basic drug. | International journal of pharmaceutics 20050811 |
| Therapeutic targeting of CCR1 attenuates established chronic fungal asthma in mice. | British journal of pharmacology 20050801 |
| Delayed chemokine receptor 1 blockade prolongs survival in collagen 4A3-deficient mice with Alport disease. | Journal of the American Society of Nephrology : JASN 20050401 |
| Chemokine receptor CCR1: a new target for progressive kidney disease. | American journal of nephrology 20050101 |
| CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome. | Kidney international 20041201 |
| Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice. | Journal of the American Society of Nephrology : JASN 20040601 |
| BX-471 Berlex. | Current opinion in investigational drugs (London, England : 2000) 20020601 |
| A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation. | The Journal of clinical investigation 20020115 |
| CCR1-specific non-peptide antagonist: efficacy in a rabbit allograft rejection model. | Immunology letters 20010402 |
| A non-peptide functional antagonist of the CCR1 chemokine receptor is effective in rat heart transplant rejection. | The Journal of biological chemistry 20010209 |
| Identification and characterization of a potent, selective, and orally active antagonist of the CC chemokine receptor-1. | The Journal of biological chemistry 20000623 |
| GAMMA-Glutamyl transpeptidase of sheep-kidney cortex. Isolation, catalytic properties and dissociation into two polypeptide chains. | European journal of biochemistry 19760102 |