1-Methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl-1H-pyrazole-5-carboxamide
| Title | Journal |
|---|---|
| Lymphocyte-Specific Protein Tyrosine Kinase (LCK) is Involved in the Aryl Hydrocarbon Receptor-Mediated Impairment of Immunoglobulin Secretion in Human Primary B Cells. | Toxicological sciences : an official journal of the Society of Toxicology 20181001 |
| In vitro toxicity and in silico docking analysis of two novel selective AH-receptor modulators. | Toxicology in vitro : an international journal published in association with BIBRA 20181001 |
| Variation in doses and duration of particulate matter exposure in bronchial epithelial cells results in upregulation of different genes associated with airway disorders. | Toxicology in vitro : an international journal published in association with BIBRA 20180901 |
| Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands. | Toxicology letters 20180801 |
| Relative effective potencies of dioxin-like compounds in rodent and human lung cell models. | Toxicology 20180701 |
| Benzo[a]pyrene activates an AhR/Src/ERK axis that contributes to CYP1A1 induction and stable DNA adducts formation in lung cells. | Toxicology letters 20180601 |
| Suppression of the IgM Response by Aryl Hydrocarbon Receptor Activation in Human Primary B Cells Involves Impairment of Immunoglobulin Secretory Processes. | Toxicological sciences : an official journal of the Society of Toxicology 20180501 |
| Diesel exhaust particulate associated chemicals attenuate expression of CXCL10 in human primary bronchial epithelial cells. | Toxicology in vitro : an international journal published in association with BIBRA 20171201 |
| Down-regulation of the expression of alcohol dehydrogenase 4 and CYP2E1 by the combination of α-endosulfan and dioxin in HepaRG human cells. | Toxicology in vitro : an international journal published in association with BIBRA 20171201 |
| Actein alleviates 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated cellular dysfunction in osteoblastic MC3T3-E1 cells. | Environmental toxicology 20171201 |
| Editor's Highlight: Ah Receptor Activation Potentiates Neutrophil Chemoattractant (C-X-C Motif) Ligand 5 Expression in Keratinocytes and Skin. | Toxicological sciences : an official journal of the Society of Toxicology 20171101 |
| Novel roles for AhR and ARNT in the regulation of alcohol dehydrogenases in human hepatic cells. | Archives of toxicology 20170101 |
| SHP-1 is directly activated by the aryl hydrocarbon receptor and regulates BCL-6 in the presence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). | Toxicology and applied pharmacology 20161101 |
| Activation of aryl hydrocarbon receptor reduces carbendazim-induced cell death. | Toxicology and applied pharmacology 20160901 |
| Aryl hydrocarbon receptor-ligand axis mediates pulmonary fibroblast migration and differentiation through increased arachidonic acid metabolism. | Toxicology 20160831 |
| Benzo[ghi]perylene activates the AHR pathway to exert biological effects on the NL-20 human bronchial cell line. | Toxicology letters 20160810 |
| Immunological characterization of the aryl hydrocarbon receptor (AHR) knockout rat in the presence and absence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). | Toxicology 20160810 |
| Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. | Toxicology and applied pharmacology 20160601 |
| TCDD promoted EMT of hFPECs via AhR, which involved the activation of EGFR/ERK signaling. | Toxicology and applied pharmacology 20160501 |
| Crosstalk between AhR and wnt/β-catenin signal pathways in the cardiac developmental toxicity of PM2.5 in zebrafish embryos. | Toxicology 20160429 |
| Kynurenine Signaling Increases DNA Polymerase Kappa Expression and Promotes Genomic Instability in Glioblastoma Cells. | Chemical research in toxicology 20160119 |
| PCB126-Induced Disruption in Gluconeogenesis and Fatty Acid Oxidation Precedes Fatty Liver in Male Rats. | Toxicological sciences : an official journal of the Society of Toxicology 20160101 |
| Aryl hydrocarbon receptor-dependent up-regulation of the heterodimeric amino acid transporter LAT1 (SLC7A5)/CD98hc (SLC3A2) by diesel exhaust particle extract in human bronchial epithelial cells. | Toxicology and applied pharmacology 20160101 |
| Quinone-mediated induction of cytochrome P450 1A1 in HepG2 cells through increased interaction of aryl hydrocarbon receptor with aryl hydrocarbon receptor nuclear translocator. | The Journal of toxicological sciences 20160101 |
| Activation of the aryl hydrocarbon receptor by carcinogenic aromatic amines and modulatory effects of their N-acetylated metabolites. | Archives of toxicology 20151201 |
| Covalent binding of quinones activates the Ah receptor in Hepa1c1c7 cells. | The Journal of toxicological sciences 20151201 |
| Arylhydrocarbon receptor-dependent mIndy (Slc13a5) induction as possible contributor to benzo[a]pyrene-induced lipid accumulation in hepatocytes. | Toxicology 20151104 |
| Cytokine responses induced by diesel exhaust particles are suppressed by PAR-2 silencing and antioxidant treatment, and driven by polar and non-polar soluble constituents. | Toxicology letters 20151014 |
| Benzo[a]pyrene-induced nitric oxide production acts as a survival signal targeting mitochondrial membrane potential. | Toxicology in vitro : an international journal published in association with BIBRA 20151001 |
| Differential Effects of Glycyrrhiza Species on Genotoxic Estrogen Metabolism: Licochalcone A Downregulates P450 1B1, whereas Isoliquiritigenin Stimulates It. | Chemical research in toxicology 20150817 |
| Aryl Hydrocarbon Receptor Ligand 5F 203 Induces Oxidative Stress That Triggers DNA Damage in Human Breast Cancer Cells. | Chemical research in toxicology 20150518 |
| Enhanced thyroid hormone breakdown in hepatocytes by mutual induction of the constitutive androstane receptor (CAR, NR1I3) and arylhydrocarbon receptor by benzo[a]pyrene and phenobarbital. | Toxicology 20150203 |
| PCB126 inhibits adipogenesis of human preadipocytes. | Toxicology in vitro : an international journal published in association with BIBRA 20150201 |
| Aryl hydrocarbon receptor-dependent regulation of miR-196a expression controls lung fibroblast apoptosis but not proliferation. | Toxicology and applied pharmacology 20141101 |
| The aryl hydrocarbon receptor suppresses osteoblast proliferation and differentiation through the activation of the ERK signaling pathway. | Toxicology and applied pharmacology 20141101 |
| The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines. | Molecular carcinogenesis 20141001 |
| Combination effects of (tri)azole fungicides on hormone production and xenobiotic metabolism in a human placental cell line. | International journal of environmental research and public health 20140901 |
| Aryl hydrocarbon receptor (AhR) attenuation of subchronic cigarette smoke-induced pulmonary neutrophilia is associated with retention of nuclear RelB and suppression of intercellular adhesion molecule-1 (ICAM-1). | Toxicological sciences : an official journal of the Society of Toxicology 20140701 |
| A novel MDCKII in vitro model for assessing ABCG2-drug interactions and regulation of ABCG2 transport activity in the caprine mammary gland by environmental pollutants and pesticides. | Toxicology in vitro : an international journal published in association with BIBRA 20140401 |
| Differentiation of human placental BeWo cells by the environmental contaminant benzo(a)pyrene. | Chemico-biological interactions 20140305 |
| Penta- and octa-bromodiphenyl ethers promote proinflammatory protein expression in human bronchial epithelial cells in vitro. | Toxicology in vitro : an international journal published in association with BIBRA 20140301 |
| The aryl hydrocarbon receptor: differential contribution to T helper 17 and T cytotoxic 17 cell development. | PloS one 20140101 |
| Aryl hydrocarbon receptor-dependent cell cycle arrest in isolated mouse oval cells. | Toxicology letters 20131023 |
| Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor. | Toxicological sciences : an official journal of the Society of Toxicology 20130501 |
| AhR-mediated effects of dioxin on neuronal acetylcholinesterase expression in vitro. | Environmental health perspectives 20130501 |
| AhR-mediated changes in global gene expression in rat liver progenitor cells. | Archives of toxicology 20130401 |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin-mediated production of reactive oxygen species is an essential step in the mechanism of action to accelerate human keratinocyte differentiation. | Toxicological sciences : an official journal of the Society of Toxicology 20130301 |
| Cyprodinil as an activator of aryl hydrocarbon receptor. | Toxicology 20130208 |
| Disruption of aryl hydrocarbon receptor homeostatic levels during embryonic stem cell differentiation alters expression of homeobox transcription factors that control cardiomyogenesis. | Environmental health perspectives 20130101 |
| Cigarette smoke condensate induces aryl hydrocarbon receptor-dependent changes in gene expression in spermatocytes. | Reproductive toxicology (Elmsford, N.Y.) 20121201 |
| The androgenic anabolic steroid tetrahydrogestrinone produces dioxin-like effects via the aryl hydrocarbon receptor. | Toxicology in vitro : an international journal published in association with BIBRA 20121001 |
| Cardiosulfa induces heart deformation in zebrafish through the AhR-mediated, CYP1A-independent pathway. | Chembiochem : a European journal of chemical biology 20120709 |
| FOXA1 is essential for aryl hydrocarbon receptor-dependent regulation of cyclin G2. | Molecular cancer research : MCR 20120501 |
| Effects of AhR ligands on the production of immunoglobulins in purified mouse B cells. | Biomedical research (Tokyo, Japan) 20120401 |
| Development of novel CH223191-based antagonists of the aryl hydrocarbon receptor. | Molecular pharmacology 20120101 |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin's suppression of 1-nitropyrene-induced p53 expression is mediated by cytochrome P450 1A1. | Chemical research in toxicology 20111219 |
| The aryl hydrocarbon receptor agonist 2,3,7,8-tetrachloro-dibenzo-p-dioxin (TCDD) alters early embryonic development in a rat IVF exposure model. | Reproductive toxicology (Elmsford, N.Y.) 20111101 |
| 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced MUC5AC expression: aryl hydrocarbon receptor-independent/EGFR/ERK/p38-dependent SP1-based transcription. | American journal of respiratory cell and molecular biology 20110801 |
| Effects of PCB126 and 17β-oestradiol on endothelium-derived vasoactive factors in human endothelial cells. | Toxicology 20110711 |
| Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism. | The Journal of pharmacology and experimental therapeutics 20110701 |
| Aryl hydrocarbon receptor-dependent upregulation of Cyp1b1 by TCDD and diesel exhaust particles in rat brain microvessels. | Fluids and barriers of the CNS 20110101 |
| CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor. | Toxicological sciences : an official journal of the Society of Toxicology 20101001 |
| Activation of the aryl hydrocarbon receptor reveals distinct requirements for IL-22 and IL-17 production by human T helper cells. | European journal of immunology 20100901 |
| Direct assessment of cumulative aryl hydrocarbon receptor agonist activity in sera from experimentally exposed mice and environmentally exposed humans. | Environmental health perspectives 20100501 |
| Up-regulation of CYP1A1 by rutaecarpine is dependent on aryl hydrocarbon receptor and calcium. | Toxicology 20091221 |
| Inhibition of UV-C light-induced apoptosis in liver cells by 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Toxicological sciences : an official journal of the Society of Toxicology 20090901 |
| Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells. | The Journal of experimental medicine 20090119 |
| Novel compound 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazo-phenyl)-amide (CH-223191) prevents 2,3,7,8-TCDD-induced toxicity by antagonizing the aryl hydrocarbon receptor. | Molecular pharmacology 20060601 |