LL Z1640-2
| Title | Journal |
|---|---|
| Resorcylic acid lactones with cytotoxic and NF-κB inhibitory activities and their structure-activity relationships. | Journal of natural products 20110527 |
| Total synthesis of TAK-kinase inhibitor LL-Z1640-2 via consecutive macrocyclization and transannular aromatization. | Organic letters 20101203 |
| Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III. | Bioorganic & medicinal chemistry letters 20100515 |
| Conformational analyses and MO studies of f152A1 and its analogues as potent protein kinase inhibitors. | Journal of chemical information and modeling 20091201 |
| Divergent syntheses of resorcylic acid lactones: L-783277, LL-Z1640-2, and hypothemycin. | Chemistry (Weinheim an der Bergstrasse, Germany) 20091102 |
| E6201 [(3S,4R,5Z,8S,9S,11E)-14-(ethylamino)-8, 9,16-trihydroxy-3,4-dimethyl-3,4,9,19-tetrahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione], a novel kinase inhibitor of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK)-1 and MEK kinase-1: in vitro characterization of its anti-inflammatory and antihyperproliferative activities. | The Journal of pharmacology and experimental therapeutics 20091101 |
| Role of a cysteine residue in the active site of ERK and the MAPKK family. | Biochemical and biophysical research communications 20070216 |
| Chemistry and biology of resorcylic acid lactones. | Chemical communications (Cambridge, England) 20070107 |
| Suppression of cadmium-induced JNK/p38 activation and HSP70 family gene expression by LL-Z1640-2 in NIH3T3 cells. | Toxicology and applied pharmacology 20040415 |