Ym-58483
| Title | Journal |
|---|---|
| Efficiency and Safety of CRAC Inhibitors in Human Rheumatoid Arthritis Xenograft Models. | Journal of immunology (Baltimore, Md. : 1950) 20170901 |
| Store-operated CRAC channel inhibitors: opportunities and challenges. | Future medicinal chemistry 20160501 |
| Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20140702 |
| Transient receptor potential canonical 3 (TRPC3) is required for IgG immune complex-induced excitation of the rat dorsal root ganglion neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120711 |
| The mechanism of injury-induced intracellular calcium concentration oscillations in the endothelium of excised rat aorta. | Journal of vascular research 20120101 |
| Vascular endothelial growth factor stimulates endothelial colony forming cells proliferation and tubulogenesis by inducing oscillations in intracellular Ca2+ concentration. | Stem cells (Dayton, Ohio) 20111101 |
| Store-operated calcium entry and non-capacitative calcium entry have distinct roles in thrombin-induced calcium signalling in human platelets. | Cell calcium 20111001 |
| Structural requirements for the inhibition of calcium mobilization and mast cell activation by the pyrazole derivative BTP2. | The international journal of biochemistry & cell biology 20110801 |
| Overexpression of transient receptor potential canonical type 1 (TRPC1) alters both store operated calcium entry and depolarization-evoked calcium signals in C2C12 cells. | Cell calcium 20110601 |
| Store-operated Ca(2+) entry (SOCE) contributes to normal skeletal muscle contractility in young but not in aged skeletal muscle. | Aging 20110601 |
| Gβγ subunits inhibit Epac-induced melanoma cell migration. | BMC cancer 20110101 |
| Store-operated Ca(2+) entry is expressed in human endothelial progenitor cells. | Stem cells and development 20101201 |
| Mechanism for carbachol-induced secretion of lacritin in cultured monkey lacrimal acinar cells. | Investigative ophthalmology & visual science 20100901 |
| Role of TRPC3 channels in ATP-induced Ca2+ signaling in principal cells of the inner medullary collecting duct. | American journal of physiology. Renal physiology 20100701 |
| Inhibition of TRPC6 channel activity contributes to the antihypertrophic effects of natriuretic peptides-guanylyl cyclase-A signaling in the heart. | Circulation research 20100625 |
| Knockdown of stromal interaction molecule 1 attenuates hepatocyte growth factor-induced endothelial progenitor cell proliferation. | Experimental biology and medicine (Maywood, N.J.) 20100301 |
| Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivo. | International immunopharmacology 20081220 |
| Novel potent and selective Ca2+ release-activated Ca2+ (CRAC) channel inhibitors. Part 3: synthesis and CRAC channel inhibitory activity of 4'-[(trifluoromethyl)pyrazol-1-yl]carboxanilides. | Bioorganic & medicinal chemistry 20081101 |
| The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo. | Pulmonary pharmacology & therapeutics 20080101 |
| Store-operated calcium entry mediates intracellular alkalinization, ERK1/2, and Akt/PKB phosphorylation in bovine neutrophils. | Journal of leukocyte biology 20071101 |
| YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models. | European journal of pharmacology 20070410 |
| Potent inhibition of store-operated Ca2+ influx and superoxide production in HL60 cells and polymorphonuclear neutrophils by the pyrazole derivative BTP2. | Journal of leukocyte biology 20070401 |
| Canonical transient receptor potential channels promote cardiomyocyte hypertrophy through activation of calcineurin signaling. | The Journal of biological chemistry 20061103 |
| A store-operated Ca(2+) influx pathway in the bag cell neurons of Aplysia. | Journal of neurophysiology 20061101 |
| Basiliolides, a class of tetracyclic C19 dilactones from Thapsia garganica, release Ca(2+) from the endoplasmic reticulum and regulate the activity of the transcription factors nuclear factor of activated T cells, nuclear factor-kappaB, and activator protein 1 in T lymphocytes. | The Journal of pharmacology and experimental therapeutics 20061001 |
| Ca2+-independent phospholipase A2 enhances store-operated Ca2+ entry in dystrophic skeletal muscle fibers. | Journal of cell science 20060915 |
| A pyrazole derivative potently inhibits lymphocyte Ca2+ influx and cytokine production by facilitating transient receptor potential melastatin 4 channel activity. | Molecular pharmacology 20060401 |
| Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylate. | The Journal of physiology 20060215 |
| TRPV6 potentiates calcium-dependent cell proliferation. | Cell calcium 20060201 |
| [TRP channels as targets for novel calcium antagonists]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20051101 |
| A functional link between store-operated and TRPC channels revealed by the 3,5-bis(trifluoromethyl)pyrazole derivative, BTP2. | The Journal of biological chemistry 20050325 |
| Potent inhibition of Ca2+ release-activated Ca2+ channels and T-lymphocyte activation by the pyrazole derivative BTP2. | The Journal of biological chemistry 20040326 |
| A pyrazole derivative, YM-58483, potently inhibits store-operated sustained Ca2+ influx and IL-2 production in T lymphocytes. | Journal of immunology (Baltimore, Md. : 1950) 20030501 |