Chaetocin
| Title | Journal |
|---|---|
| Arsenic silences hepatic PDK4 expression through activation of histone H3K9 methylatransferase G9a. | Toxicology and applied pharmacology 20160801 |
| Chaetocin inhibits IBMX-induced melanogenesis in B16F10 mouse melanoma cells through activation of ERK. | Chemico-biological interactions 20160205 |
| Oncoepigenomics: making histone lysine methylation count. | European journal of medicinal chemistry 20121001 |
| Histone methyltransferase inhibitors induce HIV-1 recovery in resting CD4(+) T cells from HIV-1-infected HAART-treated patients. | AIDS (London, England) 20120731 |
| Inhibition of histone H3K9 methyltransferases by gliotoxin and related epipolythiodioxopiperazines. | The Journal of antibiotics 20120501 |
| Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1. | Leukemia 20120401 |
| The anticancer effects of chaetocin are independent of programmed cell death and hypoxia, and are associated with inhibition of endothelial cell proliferation. | British journal of cancer 20120117 |
| The Suv39H1 methyltransferase inhibitor chaetocin causes induction of integrated HIV-1 without producing a T cell response. | FEBS letters 20111116 |
| Epigenetic regulation of HIV-1 transcription. | Epigenomics 20110801 |
| Hypoxia-inducible factor inhibitors: a survey of recent patented compounds (2004 - 2010). | Expert opinion on therapeutic patents 20110201 |
| Antihepatoma activity of chaetocin due to deregulated splicing of hypoxia-inducible factor 1α pre-mRNA in mice and in vitro. | Hepatology (Baltimore, Md.) 20110101 |
| General approach to epipolythiodiketopiperazine alkaloids: total synthesis of (+)-chaetocins A and C and (+)-12,12'-dideoxychetracin A. | Journal of the American Chemical Society 20101020 |
| Unnatural enantiomer of chaetocin shows strong apoptosis-inducing activity through caspase-8/caspase-3 activation. | Bioorganic & medicinal chemistry letters 20100901 |
| Remodeling of nuclear architecture by the thiodioxoxpiperazine metabolite chaetocin. | Experimental cell research 20100610 |
| Assessing the trypanocidal potential of natural and semi-synthetic diketopiperazines from two deep water marine-derived fungi. | Bioorganic & medicinal chemistry 20100401 |
| Total synthesis of (+)-chaetocin and its analogues: their histone methyltransferase G9a inhibitory activity. | Journal of the American Chemical Society 20100331 |
| The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase. | Antioxidants & redox signaling 20090501 |
| Chemical probes for histone-modifying enzymes. | Nature chemical biology 20081001 |
| Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress. | Blood 20070315 |
| Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. | Nature chemical biology 20050801 |