MINAPRINE DIHYDROCHLORIDE
| Title | Journal |
|---|---|
| ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: potential application for the treatment of amyotrophic lateral sclerosis. | Journal of medicinal chemistry 20120112 |
| Molecular properties and CYP2D6 substrates: central nervous system therapeutics case study and pattern analysis of a substrate database. | Drug metabolism and disposition: the biological fate of chemicals 20091101 |
| A novel p38 alpha MAPK inhibitor suppresses brain proinflammatory cytokine up-regulation and attenuates synaptic dysfunction and behavioral deficits in an Alzheimer's disease mouse model. | Journal of neuroinflammation 20070101 |
| 3-Benzidino-6(4-chlorophenyl) pyridazine blocks delayed rectifier and transient outward potassium current in acutely isolated rat hippocampal pyramidal neurons. | Neuroscience letters 20060710 |
| Selective optimization of side activities: another way for drug discovery. | Journal of medicinal chemistry 20040311 |
| Comparative molecular field analysis and QSAR on substrates binding to cytochrome p450 2D6. | Bioorganic & medicinal chemistry 20031201 |
| An aminopyridazine-based inhibitor of a pro-apoptotic protein kinase attenuates hypoxia-ischemia induced acute brain injury. | Bioorganic & medicinal chemistry letters 20031020 |
| Toxic cocaine- and convulsant-induced modification of forced swimming behaviors and their interaction with ethanol: comparison with immobilization stress. | BMC pharmacology 20020101 |
| Pharmacological evaluation of minaprine dihydrochloride, a new psychotropic drug. | Arzneimittel-Forschung 19820101 |