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LEPTOMYCIN B

CAS No.:
21609-90-5
Catalog Number:
AG00BCGF
Molecular Formula:
Molecular Weight:
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Product Description
Catalog Number:
AG00BCGF
Chemical Name:
LEPTOMYCIN B
CAS Number:
21609-90-5
IUPAC Name:
(4-bromo-2,5-dichlorophenoxy)-methoxy-phenyl-sulfanylidene-λ5-phosphane
InChI:
InChI=1S/C13H10BrCl2O2PS/c1-17-19(20,9-5-3-2-4-6-9)18-13-8-11(15)10(14)7-12(13)16/h2-8H,1H3
InChI Key:
CVRALZAYCYJELZ-UHFFFAOYSA-N
EC Number:
244-472-8
Properties
Complexity:
368  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
409.87g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
412.059g/mol
Monoisotopic Mass:
409.87g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
50.6A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
6.3  
Literature
Title Journal
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The greening of pesticide-environment interactions: some personal observations. Environmental health perspectives 20120401
Comparative study of human and mouse pregnane X receptor agonistic activity in 200 pesticides using in vitro reporter gene assays. Toxicology 20110227
Reactivation of human acetylcholinesterase and butyrylcholinesterase inhibited by leptophos-oxon with different oxime reactivators in vitro. International journal of molecular sciences 20100101
Longitudinal trends in organophosphate incidents reported to the National Pesticide Information Center, 1995-2007. Environmental health : a global access science source 20090101
Workgroup report: incorporating in vitro alternative methods for developmental neurotoxicity into international hazard and risk assessment strategies. Environmental health perspectives 20070601
Assessing exposure to organophosphorus pesticides by biomonitoring in epidemiologic studies of birth outcomes. Environmental health perspectives 20050401
Effects of prednisolone and complex of vitamin B1, B2, B6 and B12 on organophosphorus compound-induced delayed neurotoxicity. Journal of occupational health 20040901
Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environmental health perspectives 20040401
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Separation and toxicity of enantiomers of organophosphorus insecticide leptophos. Ecotoxicology and environmental safety 20030601
Inhibition of neurite outgrowth in N2a cells by leptophos and carbaryl: effects on neurofilament heavy chain, GAP-43 and HSP-70. Toxicology in vitro : an international journal published in association with BIBRA 20030201
[Neurotoxicity of organophosphorus and dithiocarbamate compounds]. Nihon eiseigaku zasshi. Japanese journal of hygiene 20030101
Neurotoxic potential of six organophosphorus compounds in adult hens. Veterinary and human toxicology 19991001
Interaction of structurally diverse pesticides with the human MDR1 gene product P-glycoprotein. Toxicology and applied pharmacology 19961101
Lymphocyte and brain neurotoxic esterase: dose and time dependence of inhibition in the hen examined with three organophosphorus esters. Toxicology and applied pharmacology 19860330
Properties