2,2',4,4'-TETRACHLOROBIPHENYL
Title | Journal |
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Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. | Toxicology and applied pharmacology 20150401 |
Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs. | Toxicology letters 20111010 |
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines. | Environmental research 20110401 |
Serum PCB levels and congener profiles among teachers in PCB-containing schools: a pilot study. | Environmental health : a global access science source 20110101 |
PCB-47, PBDE-47, and 6-OH-PBDE-47 differentially modulate human GABAA and alpha4beta2 nicotinic acetylcholine receptors. | Toxicological sciences : an official journal of the Society of Toxicology 20101201 |
Activation and potentiation of human GABAA receptors by non-dioxin-like PCBs depends on chlorination pattern. | Toxicological sciences : an official journal of the Society of Toxicology 20101101 |
Changes in mitogen-activated protein kinase in cerebellar granule neurons by polybrominated diphenyl ethers and polychlorinated biphenyls. | Toxicology and applied pharmacology 20100515 |
Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells. | Chemico-biological interactions 20091210 |
Stimulatory effects of a microbially dechlorinated polychlorinated biphenyl (PCB) mixture on rat uterine contraction in vitro. | Environmental research 20080601 |
Non-dioxin-like polychlorinated biphenyls induce a release of arachidonic acid in liver epithelial cells: a partial role of cytosolic phospholipase A(2) and extracellular signal-regulated kinases 1/2 signalling. | Toxicology 20080502 |
Differential inhibition of hepatic microsomal alkoxyresorufin O-dealkylation activities by tetrachlorobiphenyls. | Chemico-biological interactions 20070815 |
2,2',4,4'-Tetrachlorobiphenyl upregulates cyclooxygenase-2 in HL-60 cells via p38 mitogen-activated protein kinase and NF-kappaB. | Toxicology and applied pharmacology 20070615 |
Kinetic and mechanistic study of photodechlorination of 2,2',4,4'-tetrachlorobiphenyl in surfactant solutions. | Bulletin of environmental contamination and toxicology 20070201 |
In silico prediction of pregnane X receptor activators by machine learning approaches. | Molecular pharmacology 20070101 |
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | Journal of molecular graphics & modelling 20061101 |
The effect of chlorine substitution on the disposition of polychlorinated biphenyls following dermal administration. | Toxicology and applied pharmacology 20061001 |
Chronic toxicity of 2,4,2',4'-tetrabromodiphenyl ether on the marine alga Skeletonema costatum and the crustacean Daphnia magna. | Environmental toxicology and chemistry 20060601 |
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. | Journal of medicinal chemistry 20050908 |
Coplanar PCB congeners increase uterine weight and frontal cortical dopamine in the developing rat: implications for developmental neurotoxicity. | Toxicological sciences : an official journal of the Society of Toxicology 20050701 |
Effects of 2,2',4,4'-tetrachlorobiphenyl on granulocytic HL-60 cell function and expression of cyclooxygenase-2. | Toxicological sciences : an official journal of the Society of Toxicology 20050401 |
Influence of a combination of two tetrachlorobiphenyl congeners (PCB 47; PCB 77) on thyroid status, choline acetyltransferase (ChAT) activity, and short- and long-term memory in 30-day-old Sprague-Dawley rats. | Toxicology 20041015 |
Ortho-substituted but not coplanar PCBs rapidly kill cerebellar granule cells. | Toxicological sciences : an official journal of the Society of Toxicology 20040501 |
Spectral interactions of tetrachlorobiphenyls with hepatic microsomal cytochrome p450 enzymes. | Chemico-biological interactions 20031215 |
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. | Chemical research in toxicology 20031001 |
Influence of aeration on hydrophobic organic contaminant distribution and diffusive flux in estuarine sediments. | Environmental science & technology 20030815 |
Effects of PCB congeners on the immune function of Mytilus hemocytes: alterations of tyrosine kinase-mediated cell signaling. | Aquatic toxicology (Amsterdam, Netherlands) 20030508 |
Developmental exposure to polychlorinated biphenyls affects sexual behavior of rats. | Physiology & behavior 20020415 |
Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens. | Chemical research in toxicology 20010301 |
Behavioral effects following single and combined maternal exposure to PCB 77 (3,4,3',4'-tetrachlorobiphenyl) and PCB 47 (2,4,2',4'-tetrachlorobiphenyl) in rats. | Neurotoxicology and teratology 19990101 |
Environmental xenobiotics and the antihormones cyproterone acetate and spironolactone use the nuclear hormone pregnenolone X receptor to activate the CYP3A23 hormone response element. | Molecular pharmacology 19981201 |
Inhibition of growth by 2,3,7,8-tetrachlorodibenzo-p-dioxin in 5L rat hepatoma cells is associated with the presence of Ah receptor. | Carcinogenesis 19901201 |