(2S,4R)-4-METHYLGLUTAMIC ACID
| Title | Journal |
|---|---|
| Modulation of neurite outgrowth by activation of calcium-permeable kainate receptors expressed by rat nociceptive-like dorsal root ganglion neurons. | Developmental neurobiology 20111001 |
| Selective kainate receptor (GluK1) ligands structurally based upon 1H-cyclopentapyrimidin-2,4(1H,3H)-dione: synthesis, molecular modeling, and pharmacological and biostructural characterization. | Journal of medicinal chemistry 20110714 |
| Substituted 2-aminothiopen-derivatives: a potential new class of GluR6-antagonists. | European journal of medicinal chemistry 20100101 |
| Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20091101 |
| Kinetic basis of partial agonism at NMDA receptors. | Nature neuroscience 20090901 |
| The role of cation binding in determining substrate selectivity of glutamate transporters. | The Journal of biological chemistry 20090213 |
| Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7. | Journal of medicinal chemistry 20080724 |
| Comparison of [(3)H]-(2S,4R)-4-methylglutamate and [(3)H]D-aspartate as ligands for binding and autoradiographic analyses of glutamate transporters. | Neurochemistry international 20071201 |
| Subunit-specific agonist activity at NR2A-, NR2B-, NR2C-, and NR2D-containing N-methyl-D-aspartate glutamate receptors. | Molecular pharmacology 20071001 |
| Developmental changes in retrograde messengers involved in depolarization-induced suppression of excitation at parallel fiber-Purkinje cell synapses in rodents. | Journal of neurophysiology 20070101 |
| Retigabine-induced population primary afferent hyperpolarisation in vitro. | Neuropharmacology 20060901 |
| Allosteric control of an ionotropic glutamate receptor with an optical switch. | Nature chemical biology 20060101 |
| Chemoenzymatic synthesis of a series of 4-substituted glutamate analogues and pharmacological characterization at human glutamate transporters subtypes 1-3. | Journal of medicinal chemistry 20051215 |
| Altered long-term synaptic plasticity and kainate-induced Ca2+ transients in the substantia gelatinosa neurons in GLU(K6)-deficient mice. | Brain research. Molecular brain research 20051207 |
| Crystal structures of the GluR5 and GluR6 ligand binding cores: molecular mechanisms underlying kainate receptor selectivity. | Neuron 20050217 |
| Functional analysis of glutamate transporters in excitatory synaptic transmission of GLAST1 and GLAST1/EAAC1 deficient mice. | Brain research. Molecular brain research 20040928 |
| Acute and late effects on induction of allodynia by acromelic acid, a mushroom poison related structurally to kainic acid. | British journal of pharmacology 20040601 |
| Binding and transport of [3H](2S,4R)- 4-methylglutamate, a new ligand for glutamate transporters, demonstrate labeling of EAAT1 in cultured murine astrocytes. | Journal of neuroscience research 20040315 |
| Activation of ionotropic glutamate receptors on peripheral axons of primary motoneurons mediates transmitter release at the zebrafish NMJ. | Journal of neurophysiology 20040201 |
| Valproic acid inhibits histone deacetylase activity and suppresses excitotoxicity-induced GAPDH nuclear accumulation and apoptotic death in neurons. | The pharmacogenomics journal 20040101 |
| Functional properties of spontaneous EPSCs and non-NMDA receptors in rod amacrine (AII) cells in the rat retina. | The Journal of physiology 20030615 |
| SYM 2081, an agonist that desensitizes kainate receptors, attenuates capsaicin and inflammatory hyperalgesia. | Brain research 20030530 |
| Regulation of kainate receptors by protein kinase C and metabotropic glutamate receptors. | The Journal of physiology 20030501 |
| The 'glial' glutamate transporter, EAAT2 (Glt-1) accounts for high affinity glutamate uptake into adult rodent nerve endings. | Journal of neurochemistry 20030201 |
| Low-affinity kainate receptor-mediated events reduce the protective activity of phenobarbital and diphenylhydantoin against maximal electroshock in mice. | Neuropharmacology 20021201 |
| Modulation of spinal nociception by GluR5 kainate receptor ligands in acute and hyperalgesic states and the role of gabaergic mechanisms. | Neuropharmacology 20020901 |
| A non-excitatory paradigm of glutamate toxicity. | Journal of neurophysiology 20020301 |
| Evaluation of drugs acting at glutamate transporters in organotypic hippocampal cultures: new evidence on substrates and blockers in excitotoxicity. | Neurochemical research 20020201 |
| Regional mapping of low-affinity kainate receptors in mouse brain using [(3)H](2S,4R)-4-methylglutamate autoradiography. | European journal of pharmacology 20011123 |
| Role of kainate receptor activation and desensitization on the [Ca(2+)](i) changes in cultured rat hippocampal neurons. | Journal of neuroscience research 20010901 |
| [(3)H](2S,4R)-4-Methylglutamate: a novel ligand for the characterization of glutamate transporters. | Journal of neurochemistry 20010601 |
| Synthesis and receptor binding affinity of new selective GluR5 ligands. | Bioorganic & medicinal chemistry 20010401 |
| Role of non-NMDA receptors in vasopressin and oxytocin release from rat hypothalamo-neurohypophysial explants. | American journal of physiology. Regulatory, integrative and comparative physiology 20010201 |
| 4-Alkyl- and 4-cinnamylglutamic acid analogues are potent GluR5 kainate receptor agonists. | Journal of medicinal chemistry 20000518 |
| LY339434, a GluR5 kainate receptor agonist. | Neuropharmacology 19980101 |
| (2S,4R)-4-methylglutamic acid (SYM 2081): a selective, high-affinity ligand for kainate receptors. | The Journal of pharmacology and experimental therapeutics 19970101 |