Gw274150
| Title | Journal |
|---|---|
| New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors. | Current treatment options in neurology 20120201 |
| Ultrasonographic measures of synovitis in an early phase clinical trial: a double-blind, randomised, placebo and comparator controlled phase IIa trial of GW274150 (a selective inducible nitric oxide synthase inhibitor) in rheumatoid arthritis. | Clinical and experimental rheumatology 20120101 |
| Activation of hypoxia-inducible factor-1 ameliorates postischemic renal injury via inducible nitric oxide synthase. | Molecular and cellular biochemistry 20111201 |
| Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights. | Bioorganic & medicinal chemistry letters 20110715 |
| Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor. | Bioorganic & medicinal chemistry letters 20110515 |
| Neuroprotection by the selective iNOS inhibitor GW274150 in a model of Parkinson disease. | Free radical biology & medicine 20110301 |
| Lack of efficacy of the selective iNOS inhibitor GW274150 in prophylaxis of migraine headache. | Cephalalgia : an international journal of headache 20101201 |
| Inhibition of inducible nitric oxide synthase in respiratory diseases. | Biochemical Society transactions 20090801 |
| Selective inducible nitric oxide synthase inhibition has no effect on allergen challenge in asthma. | American journal of respiratory and critical care medicine 20071115 |
| y+ LAT-1 mediates transport of the potent and selective iNOS inhibitor, GW274150, in control J774 macrophages. | Amino acids 20060901 |
| An animal model of chronic inflammatory pain: pharmacological and temporal differentiation from acute models. | European journal of pain (London, England) 20060801 |
| Role of inducible nitric oxide synthase in the reduced responsiveness of the myocardium to catecholamines in a hyperdynamic, murine model of septic shock. | Critical care medicine 20060201 |
| GW274150, a novel and highly selective inhibitor of the inducible isoform of nitric oxide synthase (iNOS), shows analgesic effects in rat models of inflammatory and neuropathic pain. | Pain 20060101 |
| GW274150 and GW273629 are potent and highly selective inhibitors of inducible nitric oxide synthase in vitro and in vivo. | British journal of pharmacology 20050601 |
| Beneficial effects of GW274150 treatment on the development of experimental colitis induced by dinitrobenzene sulfonic acid. | European journal of pharmacology 20050110 |
| Inhibition or knock out of inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury. | Respiratory research 20050101 |
| 2-aminopyridines as highly selective inducible nitric oxide synthase inhibitors. Differential binding modes dependent on nitrogen substitution. | Journal of medicinal chemistry 20040603 |
| Effects of GW274150, a novel and selective inhibitor of iNOS activity, in acute lung inflammation. | British journal of pharmacology 20040301 |
| GW274150 inhibits nitric oxide production by primary cultures of rat proximal tubular cells. | Medical science monitor : international medical journal of experimental and clinical research 20031001 |
| GW274150, a potent and highly selective inhibitor of iNOS, reduces experimental renal ischemia/reperfusion injury. | Kidney international 20030301 |
| A novel, potent and selective inhibitor of the activity of inducible nitric oxide synthase (GW274150) reduces the organ injury in hemorrhagic shock. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20021201 |
| Beneficial effects of GW274150, a novel, potent and selective inhibitor of iNOS activity, in a rodent model of collagen-induced arthritis. | European journal of pharmacology 20021018 |
| NOS-II is involved in early differentiation of murine cortical, retinal and ES cell-derived neurons-an immunocytochemical and functional approach. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20020401 |
| Nitric oxide synthases: structure, function and inhibition. | The Biochemical journal 20010801 |
| Inhibitors of nitric oxide synthase in inflammatory arthritis. | IDrugs : the investigational drugs journal 19980701 |