4,4'-METHYLENEBIS(PHENYL ISOCYANATE)
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SENS-IS, a 3D reconstituted epidermis based model for quantifying chemical sensitization potency: Reproducibility and predictivity results from an inter-laboratory study. | Toxicology in vitro : an international journal published in association with BIBRA 20160401 |
Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma. | Toxicological sciences : an official journal of the Society of Toxicology 20150701 |
Connecting glutathione with immune responses to occupational methylene diphenyl diisocyanate exposure. | Chemico-biological interactions 20130905 |
Molecular determinants of humoral immune specificity for the occupational allergen, methylene diphenyl diisocyanate. | Molecular immunology 20130601 |
Polyurethane thermoplastic elastomers with inherent radiopacity for biomedical applications. | Journal of biomedical materials research. Part A 20121201 |
Occupational contact allergy to monomeric isocyanates. | Contact dermatitis 20120801 |
Identification of contact and respiratory sensitizers according to IL-4 receptor α expression and IL-2 production. | Toxicology and applied pharmacology 20120415 |
Dermal uptake study with 4,4'-diphenylmethane diisocyanate led to active sensitization. | Contact dermatitis 20120201 |
3,3'-Bis(quinolin-8-yl)-1,1'-[4,4'-methyl-enebis(4,1-phenyl-ene)]diurea. | Acta crystallographica. Section E, Structure reports online 20120101 |
Comparison of cytokine profiles in bronchoalveolar lavage fluid of mice exposed to respiratory and contact sensitizers. | The Journal of toxicological sciences 20120101 |
Occupational asthma related to low levels of airborne methylene diphenyl diisocyanate (MDI) in orthopedic casting work. | American journal of industrial medicine 20111201 |
Interrelating the acute and chronic mode of action of inhaled methylenediphenyl diisocyanate (MDI) in rats assisted by computational toxicology. | Regulatory toxicology and pharmacology : RTP 20111201 |
Isocyanate-functional adhesives for biomedical applications. Biocompatibility and feasibility study for vascular closure applications. | Journal of biomedical materials research. Part B, Applied biomaterials 20111001 |
Development of segmented polyurethane elastomers with low iodine content exhibiting radiopacity and blood compatibility. | Biomedical materials (Bristol, England) 20111001 |
Electrospun polyurethane fibers for absorption of volatile organic compounds from air. | ACS applied materials & interfaces 20111001 |
Micronuclei, hemoglobin adducts and respiratory tract irritation in mice after inhalation of toluene diisocyanate (TDI) and 4,4'-methylenediphenyl diisocyanate (MDI). | Mutation research 20110714 |
Surface functionalization of poly(ε-caprolactone) improves its biocompatibility as scaffold material for bioartificial vessel prostheses. | Journal of biomedical materials research. Part B, Applied biomaterials 20110701 |
[Bronchial challenge tests]. | Pneumologie (Stuttgart, Germany) 20110601 |
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): determination of the elicitation threshold concentration of after inhalation sensitization. | Toxicology 20110315 |
Methyl methacrylate and respiratory sensitization: a critical review. | Critical reviews in toxicology 20110301 |
Novel hard-block polyurethanes with high strength and transparency for biomedical applications. | Journal of biomaterials science. Polymer edition 20110101 |
Immune sensitization to methylene diphenyl diisocyanate (MDI) resulting from skin exposure: albumin as a carrier protein connecting skin exposure to subsequent respiratory responses. | Journal of occupational medicine and toxicology (London, England) 20110101 |
Dermal uptake and excretion of 14C-toluene diisocyante (TDI) and 14C-methylene diphenyl diisocyanate (MDI) in male rats. Clinical signs and histopathology following dermal exposure of male rats to TDI. | Toxicology letters 20101215 |
Isocyanate and total inhalable particulate air measurements in the European wood panel industry. | International journal of hygiene and environmental health 20101101 |
Application of shape memory polyurethane in orthodontic. | Journal of materials science. Materials in medicine 20101001 |
Determination of a new biomarker in subjects exposed to 4,4'-methylenediphenyl diisocyanate. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20100901 |
Theoretical study of hydrogen bonding interactions on MDI-based polyurethane. | Journal of molecular modeling 20100801 |
Rapid approach to biobased telechelics through two one-pot thiol-ene click reactions. | Biomacromolecules 20100614 |
Phthalate esters reveal skin-sensitizing activity of phenethyl isothiocyanate in mice. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100601 |
Antigenic changes in human albumin caused by reactivity with the occupational allergen diphenylmethane diisocyanate. | Analytical biochemistry 20100515 |
Microwave irradiation as a versatile tool for increasing reaction rates and yields in synthesis of optically active polyamides containing flexible L-leucine amino acid. | Amino acids 20100501 |
Extensive Analysis of Elastase-Induced Pulmonary Emphysema in Rats: ALP in the Lung, a New Biomarker for Disease Progression? | Journal of clinical biochemistry and nutrition 20100301 |
Dermal and inhalation exposure to methylene bisphenyl isocyanate (MDI) in iron foundry workers. | The Annals of occupational hygiene 20100101 |
New isocyanate-specific albumin adducts of 4,4'-methylenediphenyl diisocyanate (MDI) in rats. | Chemical research in toxicology 20091201 |
Effect of soft segment crystallization and hard segment physical crosslink on shape memory function in antibacterial segmented polyurethane ionomers. | Acta biomaterialia 20091101 |
Synthesis and characterization of iodinated polyurethane with inherent radiopacity. | Biomaterials 20091001 |
A plasmacytoid dendritic cell (CD123+/CD11c-) based assay system to predict contact allergenicity of chemicals. | Toxicology 20091001 |
[Three cases of isocyanate-induced hypersensitivity pneumonitis with different HRCT findings]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20090901 |
Graft polymerization of wood sawdust and peat with ethylene carbonate. A novel method for the preparation of supports with enhanced mechanical properties to be used in biofiltration of organic vapors. | Bioresource technology 20090101 |
Enhanced dispersion of carbon nanotubes in hyperbranched polyurethane and properties of nanocomposites. | Nanotechnology 20081210 |
Serum ferritin and transferrin levels as serologic markers of methylene diphenyl diisocyanate-induced occupational asthma. | The Journal of allergy and clinical immunology 20081001 |
Histamine release and inflammatory cell infiltration in airway Mucosa in methylene diphenyl diisocyanate (MDI)-induced occupational asthma. | Journal of clinical immunology 20080901 |
Fungal removal of gaseous hexane in biofilters packed with poly(ethylene carbonate) pine sawdust or peat composites. | Biotechnology and bioengineering 20080801 |
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): analysis of the elicitation dose-response relationship. | Toxicological sciences : an official journal of the Society of Toxicology 20080801 |
Contact sensitization to 4,4'-diaminodiphenylmethane and to isocyanates among general dermatology patients. | Contact dermatitis 20080801 |
Asthma-like syndrome in school children after accidental exposure to xylene and methylene diphenyl diisocyanate. | Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20080801 |
Fire-retardant-treated low-formaldehyde-emission particleboard made from recycled wood-waste. | Bioresource technology 20080401 |
Clinical and immunologic findings of methylene diphenyl diisocyanate-induced occupational asthma in a car upholstery factory. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20080401 |
Active single-drop microextraction for the determination of gaseous diisocyanates. | Journal of chromatography. A 20080328 |
Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20080301 |
Influence of polymorphic metabolic enzymes on biotransformation and effects of diphenylmethane diisocyanate. | International archives of occupational and environmental health 20080201 |
Brown Norway rat asthma model of diphenylmethane-4,4'-diisocyanate (MDI): impact of vehicle for topical induction. | Regulatory toxicology and pharmacology : RTP 20080201 |
Occupational airborne contact urticaria and asthma: simultaneous immediate and delayed allergy to diphenylmethane-4,4'-diisocyanate. | Contact dermatitis 20080201 |
Properties of shape memory polyurethane used as a low-temperature thermoplastic biomedical orthotic material: influence of hard segment content. | Journal of biomaterials science. Polymer edition 20080101 |
A case of isocyanate-induced asthma possibly complicated by food allergy after peanut consumption: a case report. | Journal of occupational medicine and toxicology (London, England) 20080101 |
Quantification of bromine in flame-retardant coatings by radiofrequency glow discharge-optical emission spectrometry. | Analytical and bioanalytical chemistry 20071001 |
How to optimize patch testing with diphenylmethane diisocyanate. | Contact dermatitis 20070901 |
Polyurethane networks from fatty-acid-based aromatic triols: synthesis and characterization. | Biomacromolecules 20070601 |
Biological monitoring of workers exposed to 4,4'-methylenediphenyl diisocyanate (MDI) in 19 French polyurethane industries. | International archives of occupational and environmental health 20070401 |
Airborne methylene diphenyl diisocyanate (MDI) concentrations associated with the application of polyurethane spray foam in residential construction. | Journal of occupational and environmental hygiene 20070201 |
Particleboard manufacturing: an innovative way to recycle paper sludge. | Waste management (New York, N.Y.) 20070101 |
Is it possible to improve the patch-test diagnostics for isocyanates? A stability study of petrolatum preparations of diphenylmethane-4,4'-diisocyanate and polymeric diphenylmethane diisocyanate. | Contact dermatitis 20070101 |
Fabrication of zein/hyaluronic acid fibrous membranes by electrospinning. | Journal of biomaterials science. Polymer edition 20070101 |
Determination of isocyanate biomarkers in construction site workers. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20070101 |
Associations of symptoms related to isocyanate, ureaformol, and formophenolic exposures with respiratory symptoms and lung function in coal miners. | International journal of occupational and environmental health 20070101 |
Soy polyol formulations as novel seed treatments for the management of soil-borne diseases of soybean. | Communications in agricultural and applied biological sciences 20070101 |
Partial C-fiber ablation modulates diphenylmethane-4,4'-diisocyanate (MDI)-induced respiratory allergy in Brown Norway rats. | Toxicology 20061207 |
Inconsistencies between cytokine profiles, antibody responses, and respiratory hyperresponsiveness following dermal exposure to isocyanates. | Toxicological sciences : an official journal of the Society of Toxicology 20061101 |
Biological monitoring of exposure to 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate. | International archives of occupational and environmental health 20060901 |
Evaluation of antibody binding to diisocyanate protein conjugates in a general population. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060901 |
Novel silicon-containing polyurethanes from vegetable oils as renewable resources. Synthesis and properties. | Biomacromolecules 20060801 |
Analysis of biomarkers in rats and dogs exposed to polymeric methylenediphenyl diisocyanate (pMDI) and its glutathione adduct. | Toxicology 20060515 |
Isocyanate exposure in an autobody repair and collision center. | Journal of occupational and environmental hygiene 20060301 |
Brown Norway rat asthma model of diphenylmethane 4,4'-diisocyanate. | Inhalation toxicology 20051201 |
Chemical analysis of 2,4-toluene diisocyanate, 1,6-hexamethylene diisocyanate and isophorone diisocyanate in petrolatum patch-test preparations. | Dermatitis : contact, atopic, occupational, drug 20050901 |
[Synthesis, characterization and blood compatibility studies of waterproof breathable polyurethanes]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20050801 |
Design, synthesis, and photodegradation of silicon-containing polyureas. | Chemistry (Weinheim an der Bergstrasse, Germany) 20050620 |
DNA strand breaks in the lymphocytes of workers exposed to diisocyanates: indications of individual differences in susceptibility after low-dose and short-term exposure. | Archives of toxicology 20050601 |
A chemosorptive cylindrical denuder designed for personal exposure measurements of isocyanates-evaluation on generated aerosols of 4,4'-methylenediphenyl diisocyanate. | Journal of environmental monitoring : JEM 20050501 |
Work-related asthma in the spray-on truck bed lining industry. | Journal of occupational and environmental medicine 20050501 |
Solvent-free sampling with di-n-butylamine for monitoring of isocyanates in air. | Journal of environmental monitoring : JEM 20050401 |
Thermal decomposition of methylene-4,4'-di(ethylphenyl-carbamate) to methylene-4,4'-di(phenylisocyanate). | Journal of hazardous materials 20050317 |
Cytokine mRNA profiles for isocyanates with known and unknown potential to induce respiratory sensitization. | Toxicology 20050227 |
Repeated inhalation challenge with diphenylmethane-4,4'-diisocyanate in brown Norway rats leads to a time-related increase of neutrophils in bronchoalveolar lavage after topical induction. | Inhalation toxicology 20050201 |
Structure and properties of polyurethanes prepared from triglyceride polyols by ozonolysis. | Biomacromolecules 20050101 |
Polycarbonate-urethane hard segment type influences esterase substrate specificity for human-macrophage-mediated biodegradation. | Journal of biomaterials science. Polymer edition 20050101 |
Study on rat subcutaneous reaction to experimental polyurethane elastomers. | Dental materials journal 20041201 |
Synthesis of core-shell polyurethane-urea nanoparticles containing 4,4'-methylenedi-p-phenyl diisocyanate and isophorone diisocyanate by self-assembled neutralization emulsification. | Chemical communications (Cambridge, England) 20041107 |
Allergic contact dermatitis from isocyanates among sculptors. | Dermatitis : contact, atopic, occupational, drug 20040901 |
Poor correlation between stated and found concentrations of diphenylmethane-4,4'-diisocyanate (4,4'-MDI) in petrolatum patch-test preparations. | Contact dermatitis 20040801 |
Identification and characterisation of adducts between serum albumin and 4,4'-methylenediphenyl diisocyanate (MDI) in human plasma. | Archives of toxicology 20040701 |
Beware of canine Gorilla Glue ingestions. | Veterinary and human toxicology 20040601 |
[A case of hypersensitivity pneumonitis showing acute respiratory distress syndrome due to exposure to dust containing diphenylmethane diisocyanate]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20040601 |
Acute inhalation studies with irritant aerosols: technical issues and relevance for risk characterization. | Archives of toxicology 20040501 |
Changes in macrophage function and morphology due to biomedical polyurethane surfaces undergoing biodegradation. | Journal of cellular physiology 20040401 |
MDI Exposure for Spray-On Truck Bed Lining. | Applied occupational and environmental hygiene 20031001 |
[A case of combined hypersensitivity pneumonitis and bronchial asthma due to isocyanate (MDI)]. | Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20031001 |
Occupational asthma (OA) with sensitization to diphenylmethane diisocyanate (MDI) presenting at the onset like a reactive airways dysfunction syndrome (RADS). | American journal of industrial medicine 20030901 |
Allergic contact dermatitis from dicyclohexylmethane-4,4'-diisocyanate. | Contact dermatitis 20030601 |
Enzyme induced biodegradation of polycarbonate-polyurethanes: dose dependence effect of cholesterol esterase. | Biomaterials 20030501 |
A comparison of the sampling efficiencies of a range of atmosphere samplers when collecting polymeric diphenylmethane di-isocyanate (MDI) aerosols. | Applied occupational and environmental hygiene 20030501 |
Recent developments in diisocyanate asthma. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030501 |
Occupational allergic contact dermatitis in a company manufacturing boards coated with isocyanate lacquer. | Contact dermatitis 20030501 |
Effects of thermal degradation products from polyurethane foams based on toluene diisocyanate and diphenylmethane diisocyanate on isolated, perfused lung of guinea pig. | Scandinavian journal of work, environment & health 20030401 |
Investigation of the competitive rate of derivatization of several secondary amines with phenylisocyanate (PHI), hexamethylene-1,6-diisocyanate (HDI), 4,4'-methylenebis(phenyl isocyanate) (MDI) and toluene diisocyanate (TDI) in liquid medium. | The Analyst 20030201 |
Gastric outflow obstruction after ingestion of wood glue in a dog. | Journal of the American Animal Hospital Association 20030101 |
Fate and potential environmental effects of methylenediphenyl diisocyanate and toluene diisocyanate released into the atmosphere. | Journal of the Air & Waste Management Association (1995) 20030101 |
Development, validation and characterization of an analytical method for the quantification of hydrolysable urinary metabolites and plasma protein adducts of 2,4- and 2,6-toluene diisocyanate, 1,5-naphthalene diisocyanate and 4,4'-methylenediphenyl diisocyanate. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101 |
Mouse models of diisocyanate asthma. | American journal of respiratory cell and molecular biology 20021001 |
Synthesis, characterization, and solvolysis of mono- and bis-S-(glutathionyl) adducts of methylene-bis-(phenylisocyanate) (MDI). | Chemical research in toxicology 20021001 |
N-Acetyltransferase genotypes as modifiers of diisocyanate exposure-associated asthma risk. | Pharmacogenetics 20020401 |
Critical analysis of biomonitoring endpoints for measuring exposure to polymeric diphenyl-methane-4,4'-diisocyanate (MDI) in rats: a comparison of markers of exposure and markers of effect. | Archives of toxicology 20020201 |
Mechanisms of isocyanate sensitisation. An in vitro approach. | Toxicology in vitro : an international journal published in association with BIBRA 20011201 |
Assessment of preferential Th1 or Th2 induction by low-molecular-weight compounds using a reverse transcription-polymerase chain reaction method: comparison of two mouse strains, C57BL/6 and BALB/c. | Toxicology and applied pharmacology 20011115 |
Carcinogenic risk of toluene diisocyanate and 4,4'-methylenediphenyl diisocyanate: epidemiological and experimental evidence. | Critical reviews in toxicology 20011101 |
Differentiation of the mechanism of micronuclei induced by cysteine and glutathione conjugates of methylenedi-p-phenyl diisocyanate from that of 4,4'-methylenedianiline. | Mutation research 20011018 |
Bone marrow micronucleus assay in Brown-Norway rats exposed to diphenyl-methane-4,4'-diisocyanate. | Archives of toxicology 20010601 |
[IR studies on segmented polyester polyurethaneurea elastomers]. | Guang pu xue yu guang pu fen xi = Guang pu 20010601 |
Asthma from diisocyanates is not mediated through a Type IV, patch-test-positive mechanism. | Contact dermatitis 20010401 |
Exposure to 4,4'-methylenediphenyl diisocyanate (MDI) during moulding of rigid polyurethane foam: determination of airborne MDI and urinary 4,4'-methylenedianiline (MDA). | The Analyst 20010401 |
Recent developments in diisocyanate asthma. | Current opinion in allergy and clinical immunology 20010401 |
[IR studies on hydrogen bonding in hard segment domains of segmented polyester polyurethaneurea]. | Guang pu xue yu guang pu fen xi = Guang pu 20010401 |
[IR studies on deuterated polyester polyurethaneurea elastomers]. | Guang pu xue yu guang pu fen xi = Guang pu 20010401 |
Morphology and structure of microcapsules prepared by interfacial polycondensation of methylene bis(phenyl isocyanate) with hexamethylene diamine. | Journal of microencapsulation 20010101 |
Isocyanate exposure and occupational asthma: a case-referent study. | Occupational and environmental medicine 20001201 |
Long-term follow-up of hexamethylene diisocyanate-, diphenylmethane diisocyanate-, and toluene diisocyanate-induced asthma. | American journal of respiratory and critical care medicine 20000801 |
Increase in airway hyperresponsiveness among workers exposed to methylene diphenyldiisocyanate compared to workers exposed to toluene diisocyanate at a petrochemical plant in Korea. | American journal of industrial medicine 20000601 |
Phenyl isocyanate is a potent chemical sensitizer. | Toxicology letters 19961216 |
Characterization of histamine releasing factors in diisocyanate-induced occupational asthma. | Toxicology 19960717 |
Assessment of chemicals for their potential to induce respiratory allergy in guinea pigs: A comparison of different routes of induction and confounding effects due to pulmonary hyperreactivity. | Toxicology in vitro : an international journal published in association with BIBRA 19941001 |
Acute respiratory disorder, rhinoconjunctivitis and fever associated with the pyrolysis of polyurethane derived from diphenylmethane diisocyanate. | Scandinavian journal of work, environment & health 19940601 |
Sputum eosinophilia after asthmatic responses induced by isocyanates in sensitized subjects. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 19940101 |
Variable effects of chemical allergens on serum IgE concentration in mice. Preliminary evaluation of a novel approach to the identification of respiratory sensitizers. | Journal of applied toxicology : JAT 19921001 |
Characterization of murine immune responses to allergenic diisocyanates. | Toxicology and applied pharmacology 19920201 |
Diisocyanate antigens that detect specific antibodies in exposed workers and guinea pigs. | Chemical research in toxicology 19880101 |
A study of serum antibody activity in workers with occupational exposure to diphenylmethane diisocyanate. | Allergy 19850701 |
Specific IgE antibodies in twenty-eight workers with diisocyanate-induced bronchial asthma. | Clinical allergy 19840901 |
Immunologic cross-reactivity between different albumin-bound isocyanates. | The Journal of allergy and clinical immunology 19830201 |
Use of hexyl isocyanate antigen to detect antibodies to hexamethylene diisocyanate (HDI) in sensitized guinea pigs and in a sensitized worker. | Fundamental and applied toxicology : official journal of the Society of Toxicology 19820101 |
Antibodies in hemodialysis patients against hapten-protein and hapten-erythrocytes. | The Journal of laboratory and clinical medicine 19800801 |