Name: Name:7-Chloro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthylmethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Brand: Angene
SKU: AG00BBLL
Rating: 90 (10 reviews)

7-Chloro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthylmethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one

CAS No.:

216691-95-1

Catalog Number:

AG00BBLL

Molecular Formula:

C27H21ClN2O2

Molecular Weight:

440.9208

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

5mg

99%

1 week

United States

$189

- +

10mg

99%

1 week

United States

$272

- +

50mg

99%

1 week

United States

$966

- +

Product Description

Catalog Number:

AG00BBLL

Chemical Name:

7-Chloro-5-(4-hydroxyphenyl)-1-methyl-3-(2-naphthylmethyl)-2,3-dihydro-1H-1,4-benzodiazepin-2-one

CAS Number:

216691-95-1

Molecular Formula:

C27H21ClN2O2

Molecular Weight:

440.9208

MDL Number:

MFCD30536363

IUPAC Name:

7-chloro-5-(4-hydroxyphenyl)-1-methyl-3-(naphthalen-2-ylmethyl)-3H-1,4-benzodiazepin-2-one

InChI:

InChI=1S/C27H21ClN2O2/c1-30-25-13-10-21(28)16-23(25)26(19-8-11-22(31)12-9-19)29-24(27(30)32)15-17-6-7-18-4-2-3-5-20(18)14-17/h2-14,16,24,31H,15H2,1H3

InChI Key:

HIJCSNHREFFOML-UHFFFAOYSA-N

SMILES:

Clc1ccc2c(c1)C(=NC(C(=O)N2C)Cc1ccc2c(c1)cccc2)c1ccc(cc1)O

Properties

Complexity:

704

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

440.129g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

440.927g/mol

Monoisotopic Mass:

440.129g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

52.9A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

5.6

Literature

Title	Journal
Identification and validation of the mitochondrial F1F0-ATPase as the molecular target of the immunomodulatory benzodiazepine Bz-423.	Chemistry & biology 20050401
The proapoptotic benzodiazepine Bz-423 affects the growth and survival of malignant B cells.	Cancer research 20031015
A comparison of the anticonvulsant effects of 1,4- and 1,5-benzodiazepines in the amygdala-kindled rat and their effects on motor function.	Epilepsy research 19890101

Properties