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Home Other Building Blocks H-SER-LEU-ILE-GLY-LYS-VAL-NH2

H-SER-LEU-ILE-GLY-LYS-VAL-NH2

CAS No.:
190383-13-2
Catalog Number:
AG00APCU
Molecular Formula:
C28H54N8O7
Molecular Weight:
614.7778
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%
1 week
United States
$173
- +
10mg
98%
1 week
United States
$257
- +
25mg
98%
1 week
United States
$423
- +
Product Description
Catalog Number:
AG00APCU
Chemical Name:
H-SER-LEU-ILE-GLY-LYS-VAL-NH2
CAS Number:
190383-13-2
Molecular Formula:
C28H54N8O7
Molecular Weight:
614.7778
MDL Number:
MFCD02259590
IUPAC Name:
(2S)-6-amino-2-[[2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]acetyl]amino]-N-[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]hexanamide
InChI:
InChI=1S/C28H54N8O7/c1-7-17(6)23(36-27(42)20(12-15(2)3)34-25(40)18(30)14-37)28(43)32-13-21(38)33-19(10-8-9-11-29)26(41)35-22(16(4)5)24(31)39/h15-20,22-23,37H,7-14,29-30H2,1-6H3,(H2,31,39)(H,32,43)(H,33,38)(H,34,40)(H,35,41)(H,36,42)/t17-,18-,19-,20-,22-,23-/m0/s1
InChI Key:
HOWDUIVVWDUEED-WAUHAFJUSA-N
SMILES:
NCCCC[C@@H](C(=O)N[C@H](C(=O)N)C(C)C)NC(=O)CNC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@H](CO)N)CC(C)C
Properties
Complexity:
931  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
0
Exact Mass:
614.412g/mol
Formal Charge:
0
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
9  
Isotope Atom Count:
0
Molecular Weight:
614.789g/mol
Monoisotopic Mass:
614.412g/mol
Rotatable Bond Count:
21  
Topological Polar Surface Area:
261A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.7  
Literature
Title Journal
Mixed exposure to bacterial lipopolysaccharide and seafood proteases augments inflammatory signalling in an airway epithelial cell model (A549). Toxicology and industrial health 20161101
Interleukin-17- and protease-activated receptor 2-mediated production of CXCL1 and CXCL8 modulated by cyclosporine A, vitamin D3 and glucocorticoids in human keratinocytes. The Journal of dermatology 20120701
Activation of PAR2 or/and TLR4 promotes SW620 cell proliferation and migration via phosphorylation of ERK1/2. Oncology reports 20110201
Activation of chloride secretion via proteinase-activated receptor 2 in a human eccrine sweat gland cell line--NCL-SG3. Experimental dermatology 20080601
Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis. Biochemical and biophysical research communications 20080530
Induction of inflammatory cytokine release from human umbilical vein endothelial cells by agonists of proteinase-activated receptor-2. Clinical and experimental pharmacology & physiology 20080101
Proinflammatory and proliferative responses of human proximal tubule cells to PAR-2 activation. American journal of physiology. Renal physiology 20071101
Protease-activated receptor-1 (PAR1) and PAR2 but not PAR4 mediate relaxations in lower esophageal sphincter. Regulatory peptides 20070705
Distinct roles for PAR1- and PAR2-mediated vasomotor modulation in human arterial and venous conduits. Journal of thrombosis and haemostasis : JTH 20070101
Induction of lactoferrin and IL-8 release from human neutrophils by tryptic enzymes via proteinase activated receptor-2. Cell biology international 20060901
Properties