SAUCHINONE
Title | Journal |
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Sauchinone exerts anticancer effects by targeting AMPK signaling in hepatocellular carcinoma cells. | Chemico-biological interactions 20170105 |
Nodularin induces tumor necrosis factor-alpha and mitogen-activated protein kinases (MAPK) and leads to induction of endoplasmic reticulum stress. | Toxicology and applied pharmacology 20160601 |
Sauchinone attenuates liver fibrosis and hepatic stellate cell activation through TGF-β/Smad signaling pathway. | Chemico-biological interactions 20141205 |
Quantitative determination of sauchinone in rat plasma by liquid chromatography-mass spectrometry. | Biomedical chromatography : BMC 20121001 |
Protective effect of sauchinone against regional myocardial ischemia/reperfusion injury: inhibition of p38 MAPK and JNK death signaling pathways. | Journal of Korean medical science 20120501 |
Protective effect of sauchinone on methamphetamine-induced neurotoxicity in mice. | Journal of pharmacological sciences 20120101 |
Nrf2-mediated liver protection by sauchinone, an antioxidant lignan, from acetaminophen toxicity through the PKCδ-GSK3β pathway. | British journal of pharmacology 20110801 |
Sauchinone protects pancreatic β cells against cytokine-mediated toxicity. | Toxicology in vitro : an international journal published in association with BIBRA 20110301 |
Sauchinone suppresses pro-inflammatory mediators by inducing heme oxygenase-1 in RAW264.7 macrophages. | Biological & pharmaceutical bulletin 20110101 |
Sauchinone, a lignan from Saururus chinensis, reduces tumor necrosis factor-alpha production through the inhibition of c-raf/MEK1/2/ERK 1/2 pathway activation. | International immunopharmacology 20100901 |
Protective effect of sauchinone by upregulating heme oxygenase-1 via the P38 MAPK and Nrf2/ARE pathways in HepG2 cells. | Planta medica 20100101 |
Sauchinone reduces oxygen-glucose deprivation-evoked neuronal cell death via suppression of intracellular radical production. | Archives of pharmacal research 20091101 |
Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury. | Free radical biology & medicine 20091001 |
Inhibition of osteoclast differentiation and bone resorption by sauchinone. | Biochemical pharmacology 20070915 |
Sauchinone, a lignan from Saururus chinensis, suppresses iNOS expression through the inhibition of transactivation activity of RelA of NF-kappaB. | Planta medica 20031201 |
Sauchinone, a lignan from Saururus chinensis, inhibits staurosporine-induced apoptosis in C6 rat glioma cells. | Biological & pharmaceutical bulletin 20031001 |
Inhibition of lipopolysaccharide-inducible nitric oxide synthase, TNF-alpha and COX-2 expression by sauchinone effects on I-kappaBalpha phosphorylation, C/EBP and AP-1 activation. | British journal of pharmacology 20030501 |