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Ipamorelin

CAS No.:
170851-70-4
Catalog Number:
AG00AOZR
Molecular Formula:
C38H49N9O5
Molecular Weight:
711.8530
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%(HPLC)
In Stock USA
United States
$69
- +
25mg
98%(HPLC)
In Stock USA
United States
$214
- +
100mg
98%(HPLC)
In Stock USA
United States
$700
- +
Product Description
Catalog Number:
AG00AOZR
Chemical Name:
Ipamorelin
CAS Number:
170851-70-4
Molecular Formula:
C38H49N9O5
Molecular Weight:
711.8530
MDL Number:
MFCD02179658
IUPAC Name:
(2S)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
InChI:
InChI=1S/C38H49N9O5/c1-38(2,41)37(52)47-32(21-28-22-42-23-43-28)36(51)46-31(20-25-15-16-26-12-6-7-13-27(26)18-25)35(50)45-30(19-24-10-4-3-5-11-24)34(49)44-29(33(40)48)14-8-9-17-39/h3-7,10-13,15-16,18,22-23,29-32H,8-9,14,17,19-21,39,41H2,1-2H3,(H2,40,48)(H,42,43)(H,44,49)(H,45,50)(H,46,51)(H,47,52)/t29-,30+,31+,32-/m0/s1
InChI Key:
NEHWBYHLYZGBNO-BVEPWEIPSA-N
SMILES:
NCCCC[C@@H](C(=O)N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccc2c(c1)cccc2)NC(=O)[C@@H](NC(=O)C(N)(C)C)Cc1c[nH]cn1
UNII:
Y9M3S784Z6
Properties
Complexity:
1200  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
711.386g/mol
Formal Charge:
0
Heavy Atom Count:
52  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
8  
Isotope Atom Count:
0
Molecular Weight:
711.868g/mol
Monoisotopic Mass:
711.386g/mol
Rotatable Bond Count:
19  
Topological Polar Surface Area:
240A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.8  
Literature
Title Journal
Mechanism of ipamorelin-evoked insulin release from the pancreas of normal and diabetic rats. Neuro endocrinology letters 20041201
Stimulation of growth hormone secretion from seabream pituitary cells in primary culture by growth hormone secretagogues is independent of growth hormone transcription. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20041001
[Ghrelin-related drugs: clinical perspectives]. Nihon rinsho. Japanese journal of clinical medicine 20040901
Growth hormone (GH) hypersecretion and GH receptor resistance in streptozotocin diabetic mice in response to a GH secretagogue. Experimental diabesity research 20030101
The influence of conformational restriction in the C-terminus of growth hormone secretagogues on their potency. European journal of medicinal chemistry 20020601
The growth hormone secretagogue ipamorelin counteracts glucocorticoid-induced decrease in bone formation of adult rats. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20011001
Highly potent growth hormone secretagogues: hybrids of NN703 and ipamorelin. Bioorganic & medicinal chemistry letters 20010723
Structural similarity of ghrelin derivatives to peptidyl growth hormone secretagogues. Biochemical and biophysical research communications 20010615
Properties