Home Other Building Blocks CYCLO (ARG-GLY-ASP-D-PHE-LYS)

CYCLO (ARG-GLY-ASP-D-PHE-LYS)

CAS No.:
161552-03-0
Catalog Number:
AG00AOJO
Molecular Formula:
C29H42F3N9O9
Molecular Weight:
717.6939
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%
1 week
United States
$250
- +
10mg
98%
1 week
United States
$357
- +
50mg
98%
1 week
United States
$973
- +
100mg
98%
1 week
United States
$1307
- +
Product Description
Catalog Number:
AG00AOJO
Chemical Name:
CYCLO (ARG-GLY-ASP-D-PHE-LYS)
CAS Number:
161552-03-0
Molecular Formula:
C29H42F3N9O9
Molecular Weight:
717.6939
MDL Number:
MFCD00937400
IUPAC Name:
2-[(2S,5R,8S,11S)-8-(4-aminobutyl)-5-benzyl-11-[3-(diaminomethylideneamino)propyl]-3,6,9,12,15-pentaoxo-1,4,7,10,13-pentazacyclopentadec-2-yl]acetic acid
InChI:
InChI=1S/C27H41N9O7/c28-11-5-4-9-18-24(41)34-17(10-6-12-31-27(29)30)23(40)32-15-21(37)33-20(14-22(38)39)26(43)36-19(25(42)35-18)13-16-7-2-1-3-8-16/h1-3,7-8,17-20H,4-6,9-15,28H2,(H,32,40)(H,33,37)(H,34,41)(H,35,42)(H,36,43)(H,38,39)(H4,29,30,31)/t17-,18-,19+,20-/m0/s1
InChI Key:
NVHPXYIRNJFKTE-HAGHYFMRSA-N
SMILES:
OC(=O)C(F)(F)F.NCCCCC1NC(=O)C(Cc2ccccc2)NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C(NC1=O)CCCN=C(N)N
Properties
Complexity:
1010  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
603.313g/mol
Formal Charge:
0
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
9  
Isotope Atom Count:
0
Molecular Weight:
603.681g/mol
Monoisotopic Mass:
603.313g/mol
Rotatable Bond Count:
12  
Topological Polar Surface Area:
273A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-4.7  
Literature
Title Journal
Failure of active targeting by a cholesterol-anchored ligand and improvement by altering the lipid composition to prevent ligand desorption. International journal of pharmaceutics 20180130
Tailored polymer-lipid hybrid nanoparticles for the delivery of drug conjugate: dual strategy for brain targeting. Colloids and surfaces. B, Biointerfaces 20150201
A cyclen-based tetraphosphinate chelator for the preparation of radiolabeled tetrameric bioconjugates. Chemistry (Weinheim an der Bergstrasse, Germany) 20130610
cRGD-functionalized polymeric magnetic nanoparticles as a dual-drug delivery system for safe targeted cancer therapy. Pharmacological research 20130401
Efficient synthesis of diverse heterobifunctionalized clickable oligo(ethylene glycol) linkers: potential applications in bioconjugation and targeted drug delivery. Organic & biomolecular chemistry 20130221
Microfluidic radiolabeling of biomolecules with PET radiometals. Nuclear medicine and biology 20130101
Transferrin-modified c[RGDfK]-paclitaxel loaded hybrid micelle for sequential blood-brain barrier penetration and glioma targeting therapy. Molecular pharmaceutics 20120604
Microfluidic labeling of biomolecules with radiometals for use in nuclear medicine. Lab on a chip 20101221
Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes. Organic & biomolecular chemistry 20070321
Properties