1,2,3,4,6-Penta-O-galloyl-beta-D-glucopyranose
| Title | Journal |
|---|---|
| Reactive oxygen species-mediated activation of JNK and down-regulation of DAXX are critically involved in penta-O-galloyl-beta-d-glucose-induced apoptosis in chronic myeloid leukemia K562 cells. | Biochemical and biophysical research communications 20120803 |
| A review of animal and human studies for management of benign prostatic hyperplasia with natural products: perspective of new pharmacological agents. | Inflammation & allergy drug targets 20120601 |
| Hamamelitannin from witch hazel (Hamamelis virginiana) displays specific cytotoxic activity against colon cancer cells. | Journal of natural products 20120127 |
| Aqueous Extract of Paeonia suffruticosa Inhibits Migration and Metastasis of Renal Cell Carcinoma Cells via Suppressing VEGFR-3 Pathway. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Involvement of iron in biofilm formation by Staphylococcus aureus. | PloS one 20120101 |
| A gallotannin-rich fraction from Caesalpinia spinosa (Molina) Kuntze displays cytotoxic activity and raises sensitivity to doxorubicin in a leukemia cell line. | BMC complementary and alternative medicine 20120101 |
| Gelatin tannate reduces the proinflammatory effects of lipopolysaccharide in human intestinal epithelial cells. | Clinical and experimental gastroenterology 20120101 |
| Insulin receptor signaling activated by penta-O-galloyl-α-D: -glucopyranose induces p53 and apoptosis in cancer cells. | Apoptosis : an international journal on programmed cell death 20110901 |
| Pharmacological evaluation of insulin mimetic novel suppressors of PEPCK gene transcription from Paeoniae Rubra Radix. | Journal of ethnopharmacology 20110901 |
| The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-β-D-glucose-treated MDA-MB-231 breast cancer cells: molecular target on cancer metabolism. | Molecules and cells 20110831 |
| 1,2,3,4,6-penta-O-galloyl-β-D-glucose, quercetin, curcumin and lycopene induce cell-cycle arrest in MDA-MB-231 and BT474 cells through downregulation of Skp2 protein. | Journal of agricultural and food chemistry 20110622 |
| Oral administration of penta-O-galloyl-β-D-glucose suppresses triple-negative breast cancer xenograft growth and metastasis in strong association with JAK1-STAT3 inhibition. | Carcinogenesis 20110601 |
| 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model. | Kidney international 20110301 |
| Conformation of the tridimensional structure of 1,2,3,4,6-pentagalloyl-β-D-glucopyranose (PGG) by (1)H NMR, NOESY and theoretical study and membrane interaction in a simulated phospholipid bilayer: a first insight. | Magnetic resonance in chemistry : MRC 20110301 |
| A novel small molecule 1,2,3,4,6-penta-O-galloyl-α-D-glucopyranose mimics the antiplatelet actions of insulin. | PloS one 20110101 |
| Bioactivity-guided isolation of 1,2,3,4,6-Penta-O-galloyl-D-glucopyranose from Paeonia lactiflora roots as a PTP1B inhibitor. | Journal of natural products 20100924 |
| Oenothera paradoxa defatted seeds extract and its bioactive component penta-O-galloyl-β-D-glucose decreased production of reactive oxygen species and inhibited release of leukotriene B4, interleukin-8, elastase, and myeloperoxidase in human neutrophils. | Journal of agricultural and food chemistry 20100922 |
| Intestinal alpha-glucosidase inhibitory activity and toxicological evaluation of Nymphaea stellata flowers extract. | Journal of ethnopharmacology 20100915 |
| Antioxidant effects of secondary metabolites from Geranium psilostemon. | Natural product communications 20100601 |
| Tellimagrandin I, HCV invasion inhibitor from Rosae Rugosae Flos. | Bioorganic & medicinal chemistry letters 20100301 |
| Simple in vitro assays to identify amyloid-beta aggregation blockers for Alzheimer's disease therapy. | Journal of Alzheimer's disease : JAD 20100101 |
| Effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on elastase and hyaluronidase activities and its type II collagen expression. | Acta poloniae pharmaceutica 20100101 |
| 1,2,3,4,6-penta-O-galloyl-beta-D-glucose protects splenocytes against radiation-induced apoptosis in murine splenocytes. | Biological & pharmaceutical bulletin 20100101 |
| Penta-O-galloyl-beta-D-glucose induces G1 arrest and DNA replicative S-phase arrest independently of cyclin-dependent kinase inhibitor 1A, cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple negative xenograft growth. | Breast cancer research : BCR 20100101 |
| 1,2,3,4,6-Penta-O-galloly-beta-D-glucose suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1α and signaling in LNCaP prostate cancer cells. | Biological & pharmaceutical bulletin 20100101 |
| Polyphenol-stabilized tubular elastin scaffolds for tissue engineered vascular grafts. | Tissue engineering. Part A 20091001 |
| Suppression of thymus- and activation-regulated chemokine (TARC/CCL17) production by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose via blockade of NF-kappaB and STAT1 activation in the HaCaT cells. | Biochemical and biophysical research communications 20090911 |
| [Chemical constituents from roots of Distylium myricoides]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090901 |
| Antioxidant and hepatoprotective activities of thai mango seed kernel extract. | Planta medica 20090801 |
| Melanogenesis inhibition by gallotannins from Chinese galls in B16 mouse melanoma cells. | Biological & pharmaceutical bulletin 20090801 |
| A traditional medicinal herb Paeonia suffruticosa and its active constituent 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose have potent anti-aggregation effects on Alzheimer's amyloid beta proteins in vitro and in vivo. | Journal of neurochemistry 20090601 |
| Penta-O-galloyl-beta-D-glucose induces S- and G(1)-cell cycle arrests in prostate cancer cells targeting DNA replication and cyclin D1. | Carcinogenesis 20090501 |
| Penta-O-galloyl-beta-D-glucose suppresses prostate cancer bone metastasis by transcriptionally repressing EGF-induced MMP-9 expression. | Journal of agricultural and food chemistry 20090422 |
| 1,2,3,4,6-penta-O-galloyl-beta-D-glucose attenuates renal cell migration, hyaluronan expression, and crystal adhesion. | European journal of pharmacology 20090315 |
| Tyrosinase inhibitors isolated from the roots of Paeonia suffruticosa. | Journal of cosmetic science 20090101 |
| Novel biological properties of Oenothera paradoxa defatted seed extracts: effects on metallopeptidase activity. | Journal of agricultural and food chemistry 20080910 |
| 1,2,3,4,6-penta-O-galloyl-beta-D-glucose from Galla Rhois protects primary rat hepatocytes from necrosis and apoptosis. | Planta medica 20080901 |
| Penta-1,2,3,4,6-O-galloyl-beta-D-glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo. | Molecular cancer therapeutics 20080901 |
| Elaeocarpus sylvestris modulates gamma-ray-induced immunosuppression in mice: implications in radioprotection. | Phytotherapy research : PTR 20080801 |
| Antioxidative activity of geranium (Pelargonium inquinans Ait) and its active component, 1,2,3,4,6-penta-O-galloyl-beta-D-glucose. | Phytotherapy research : PTR 20080401 |
| [Determination of 1, 2, 3, 4, 6-penta-O-galloyl-D-glucose in forty four kinds of Chinese traditional medicines by HPLC]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080301 |
| Bioactivity-guided isolation of the active compounds from Rosa nutkana and quantitative analysis of ascorbic acid by HPLC. | Canadian journal of physiology and pharmacology 20070901 |
| The isolation of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose from Acer truncatum Bunge by high-speed counter-current chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501 |
| Elastin stabilization for treatment of abdominal aortic aneurysms. | Circulation 20070403 |
| Protein binding and astringent taste of a polymeric procyanidin, 1,2,3,4,6-penta-O-galloyl-beta-D-glucopyranose, castalagin, and grandinin. | Journal of agricultural and food chemistry 20061213 |
| In vitro antiviral activity of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose against hepatitis B virus. | Biological & pharmaceutical bulletin 20061001 |
| [Studies on HPLC fingerprint of cortex moutan]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061001 |
| Synthesis and structure-activity relationship study of antidiabetic penta-O-galloyl-D-glucopyranose and its analogues. | Journal of medicinal chemistry 20060504 |
| 1,2,3,4,6-penta-O-galloyl-beta-D-glucose up-regulates heme oxygenase-1 expression by stimulating Nrf2 nuclear translocation in an extracellular signal-regulated kinase-dependent manner in HepG2 cells. | World journal of gastroenterology 20060114 |
| Role of peptide primary sequence in polyphenol-protein recognition: an example with neurotensin. | Biochimica et biophysica acta 20051130 |
| Vasodilatory and anti-inflammatory effects of the 1,2,3,4,6-penta-O-galloyl-beta-D-glucose (PGG) via a nitric oxide-cGMP pathway. | European journal of pharmacology 20051107 |
| Phenolic constituents of galla Rhois with hepatoprotective effects on tacrine- and nitrofurantoin-induced cytotoxicity in Hep G2 cells. | Biological & pharmaceutical bulletin 20051101 |
| Natural anti-diabetic compound 1,2,3,4,6-penta-O-galloyl-D-glucopyranose binds to insulin receptor and activates insulin-mediated glucose transport signaling pathway. | Biochemical and biophysical research communications 20051021 |
| Enzymology of gallotannin and ellagitannin biosynthesis. | Phytochemistry 20050901 |
| Anticoagulant 1,2,3,4,6-pentagalloyl-beta-D-glucopyranose isolated from geranium (Pelargonium inquinans Ait). | Archives of pharmacal research 20050901 |
| Penta-O-galloyl-beta-D-glucose suppresses tumor growth via inhibition of angiogenesis and stimulation of apoptosis: roles of cyclooxygenase-2 and mitogen-activated protein kinase pathways. | Carcinogenesis 20050801 |
| Beta-secretase (BACE1) inhibitors from Sanguisorbae Radix. | Archives of pharmacal research 20050701 |
| Green tea: Health benefits as cancer preventive for humans. | Chemical record (New York, N.Y.) 20050101 |
| Chemical identification of the sources of commercial Fructus Chebulae. | Phytochemical analysis : PCA 20050101 |
| In vitro anti-HCV activities of Saxifraga melanocentra and its related polyphenolic compounds. | Antiviral chemistry & chemotherapy 20050101 |
| Antiviral compounds from traditional Chinese medicines Galla Chinese as inhibitors of HCV NS3 protease. | Bioorganic & medicinal chemistry letters 20041220 |
| Quantitative examination of oxidized polyphenol-protein complexes. | Journal of agricultural and food chemistry 20041006 |
| Theaflavin-3,3'-digallate and penta-O-galloyl-beta-D-glucose inhibit rat liver microsomal 5alpha-reductase activity and the expression of androgen receptor in LNCaP prostate cancer cells. | Carcinogenesis 20040701 |
| Characterization of soluble non-covalent complexes between bovine serum albumin and beta-1,2,3,4,6-penta-O-galloyl-D-glucopyranose by MALDI-TOF MS. | Journal of agricultural and food chemistry 20040616 |
| 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose blocks endothelial cell growth and tube formation through inhibition of VEGF binding to VEGF receptor. | Cancer letters 20040510 |
| Penta-O-galloyl-beta-D-glucose inhibits phorbol myristate acetate-induced interleukin-8 [correction of intereukin-8] gene expression in human monocytic U937 cells through its inactivation of nuclear factor-kappaB. | International immunopharmacology 20040301 |
| Novel lipid-peroxidation- and cyclooxygenase-inhibitory tannins from Picrorhiza kurroa seeds. | Chemistry & biodiversity 20040301 |
| Inhibition of inducible nitric oxide synthase and cyclooxygenase-2 activity by 1,2,3,4,6-penta-O-galloyl-beta-D-glucose in murine macrophage cells. | Archives of pharmacal research 20031001 |
| Paeonianins A-E, new dimeric and monomeric ellagitannins from the fruits of Paeonia lactiflora. | Journal of natural products 20030601 |
| Oxidation of pentagalloylglucose to the ellagitannin, tellimagrandin II, by a phenol oxidase from Tellima grandiflora leaves. | Phytochemistry 20030201 |
| Inhibitory effects of the root cortex of Paeonia suffruticosa on interleukin-8 and macrophage chemoattractant protein-1 secretions in U937 cells. | Journal of ethnopharmacology 20030101 |
| Two new and four known polyphenolics obtained as new cell-cycle inhibitors from Rubus aleaefolius Poir. | Journal of Asian natural products research 20021201 |
| Fatty acid synthase inhibitors from plants: isolation, structure elucidation, and SAR studies. | Journal of natural products 20021201 |
| Gallotannin biosynthesis: two new galloyltransferases from Rhus typhina leaves preferentially acylating hexa- and heptagalloylglucoses. | Planta 20021101 |
| Penta-O-galloyl-beta-D-glucose inhibits the invasion of mouse melanoma by suppressing metalloproteinase-9 through down-regulation of activator protein-1. | European journal of pharmacology 20021025 |
| 1,2,3,4,6-Penta-O-galloyl-beta-D-glucose protects rat neuronal cells (Neuro 2A) from hydrogen peroxide-mediated cell death via the induction of heme oxygenase-1. | Neuroscience letters 20020809 |
| Inhibition of HIV-1 integrase by galloyl glucoses from Terminalia chebula and flavonol glycoside gallates from Euphorbia pekinensis. | Planta medica 20020501 |
| Respiratory syncytial virus infection induces matrix metalloproteinase-9 expression in epithelial cells. | Archives of virology 20020101 |
| In vitro anti-proliferative effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells. | Cancer letters 20011210 |
| Gallotannin biosynthesis: beta-glucogallin: hexagalloyl 3-O-galloyltransferase from Rhus typhina leaves. | Phytochemistry 20011101 |
| Ellagitannins and hexahydroxydiphenoyl esters as inhibitors of vertebrate squalene epoxidase. | Journal of natural products 20010801 |
| Ellagic acid formation from galloylglucoses by a crude enzyme of Cornus capitata adventitious roots. | Bioscience, biotechnology, and biochemistry 20010801 |
| Seasonal variation in the content of hydrolysable tannins in leaves of Betula pubescens. | Phytochemistry 20010501 |
| Prolyl endopeptidase inhibitors from the underground part of Rhodiola sachalinensis. | Chemical & pharmaceutical bulletin 20010401 |
| Inhibitory effects of ellagi- and gallotannins on rat intestinal alpha-glucosidase complexes. | Bioscience, biotechnology, and biochemistry 20010301 |
| Identification of hydrolysable tannins in the reaction zone of Eucalyptus nitens wood by high performance liquid chromatography--electrospray ionisation mass spectrometry. | Phytochemical analysis : PCA 20010101 |
| Induction of apoptosis by penta-O-galloyl-beta-D-glucose through activation of caspase-3 in human leukemia HL-60 cells. | European journal of pharmacology 19990924 |
| A new flavonol glycoside gallate ester from Acer okamotoanum and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase. | Journal of natural products 19980101 |
| Sulfated pentagalloyl glucose (Y-ART-3) inhibits HIV replication and cytopathic effects in vitro, and reduces HIV infection in hu-PBL-SCID mice. | Antiviral research 19960501 |
| Inhibition of human immunodeficiency viral replication by tannins and related compounds. | Antiviral research 19920501 |