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Home Other Building Blocks SDZ 220-581

SDZ 220-581

CAS No.:
174575-17-8
Catalog Number:
AG00AOH2
Molecular Formula:
C16H17ClNO5P
Molecular Weight:
369.7366
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10mg
98%
1 week
United States
$307
- +
50mg
98%
1 week
United States
$1123
- +
Product Description
Catalog Number:
AG00AOH2
Chemical Name:
SDZ 220-581
CAS Number:
174575-17-8
Molecular Formula:
C16H17ClNO5P
Molecular Weight:
369.7366
MDL Number:
MFCD09878263
IUPAC Name:
(2S)-2-amino-3-[3-(2-chlorophenyl)-5-(phosphonomethyl)phenyl]propanoic acid
InChI:
InChI=1S/C16H17ClNO5P/c17-14-4-2-1-3-13(14)12-6-10(8-15(18)16(19)20)5-11(7-12)9-24(21,22)23/h1-7,15H,8-9,18H2,(H,19,20)(H2,21,22,23)/t15-/m0/s1
InChI Key:
VBRJFXSFCYEZMQ-HNNXBMFYSA-N
SMILES:
N[C@H](C(=O)O)Cc1cc(cc(c1)c1ccccc1Cl)CP(=O)(O)O
Properties
Complexity:
485  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
369.053g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
369.738g/mol
Monoisotopic Mass:
369.053g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
121A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.2  
Literature
Title Journal
Differential effects of NMDA antagonists on high frequency and gamma EEG oscillations in a neurodevelopmental model of schizophrenia. Neuropharmacology 20120301
Behavioral characterization of a mutant mouse strain lacking D-amino acid oxidase activity. Behavioural brain research 20110202
Encoding of the cough reflex in anesthetized guinea pigs. American journal of physiology. Regulatory, integrative and comparative physiology 20110201
NMDA receptor-mediated long-term alterations in epileptiform activity in experimental chronic epilepsy. Neuropharmacology 20090201
Activation of rat ventral tegmental area dopamine neurons by endogenous kynurenic acid: a pharmacological analysis. Neuropharmacology 20071201
NMDA receptor trafficking at recurrent synapses stabilizes the state of the CA3 network. Journal of neurophysiology 20071101
Contributions of receptor desensitization and saturation to plasticity at the retinogeniculate synapse. Neuron 20020227
The competitive NMDA receptor antagonist SDZ 220-581 reverses haloperidol-induced catalepsy in rats. European journal of pharmacology 19961031
Properties