6,7-Dichloroindoline-2,3-dione
Title | Journal |
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Electrical conduction along endothelial cell tubes from mouse feed arteries: confounding actions of glycyrrhetinic acid derivatives. | British journal of pharmacology 20120501 |
Opening of small and intermediate calcium-activated potassium channels induces relaxation mainly mediated by nitric-oxide release in large arteries and endothelium-derived hyperpolarizing factor in small arteries from rat. | The Journal of pharmacology and experimental therapeutics 20111201 |
IKCa agonist (NS309)-elicited all-or-none dehydration response of human red blood cells is cell-age dependent. | Cell calcium 20111101 |
KCa2 channels activation prevents [Ca2+]i deregulation and reduces neuronal death following glutamate toxicity and cerebral ischemia. | Cell death & disease 20110401 |
Altered expression and function of small-conductance (SK) Ca(2+)-activated K+ channels in pilocarpine-treated epileptic rats. | Brain research 20100812 |
Openers of small conductance calcium-activated potassium channels selectively enhance NO-mediated bradykinin vasodilatation in porcine retinal arterioles. | British journal of pharmacology 20100701 |
Twenty-four-hour exposure to altered blood flow modifies endothelial Ca2+-activated K+ channels in rat mesenteric arteries. | The Journal of pharmacology and experimental therapeutics 20100401 |
Mechanisms underlying epithelium-dependent relaxation in rat bronchioles: analogy to EDHF-type relaxation in rat pulmonary arteries. | American journal of physiology. Lung cellular and molecular physiology 20100401 |
Arterial stiffness is regulated by nitric oxide and endothelium-derived hyperpolarizing factor during changes in blood flow in humans. | Hypertension (Dallas, Tex. : 1979) 20100301 |
NS309 restores EDHF-type relaxation in mesenteric small arteries from type 2 diabetic ZDF rats. | British journal of pharmacology 20100101 |
Role of calcium-activated potassium channels with small conductance in bradykinin-induced vasodilation of porcine retinal arterioles. | Investigative ophthalmology & visual science 20090801 |
Openers of SKCa and IKCa channels enhance agonist-evoked endothelial nitric oxide synthesis and arteriolar vasodilation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090401 |
TNF-alpha-mediates neuroprotection against glutamate-induced excitotoxicity via NF-kappaB-dependent up-regulation of K2.2 channels. | Journal of neurochemistry 20081101 |
Restoration of calcium influx corrects membrane hyperexcitability in injured rat dorsal root ganglion neurons. | Anesthesia and analgesia 20080901 |
Calcium-activated potassium channels contribute to human skeletal muscle microvascular endothelial dysfunction related to cardiopulmonary bypass. | Surgery 20080801 |
Openers of calcium-activated potassium channels and endothelium-dependent hyperpolarizations in the guinea pig carotid artery. | Naunyn-Schmiedeberg's archives of pharmacology 20080401 |
Fluorescence-based Tl(+)-influx assays as a novel approach for characterization of small-conductance Ca(2+)-activated K (+) channel modulators. | Methods in molecular biology (Clifton, N.J.) 20080101 |
Effects of methyl beta-cyclodextrin on EDHF responses in pig and rat arteries; association between SK(Ca) channels and caveolin-rich domains. | British journal of pharmacology 20070601 |
Selective inhibition of carboxylesterases by isatins, indole-2,3-diones. | Journal of medicinal chemistry 20070419 |
Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) reduces afterhyperpolarizing current in hippocampal CA1 neurons. | Molecular pharmacology 20061101 |
Urodynamic effects of intravesical administration of the new small/intermediate conductance calcium activated potassium channel activator NS309 in freely moving, conscious rats. | The Journal of urology 20060901 |
Activation of human IK and SK Ca2+ -activated K+ channels by NS309 (6,7-dichloro-1H-indole-2,3-dione 3-oxime). | Biochimica et biophysica acta 20041011 |