EGFR and PKC are involved in the activation of ERK1/2 and p90 RSK and the subsequent proliferation of SNU-407 colon cancer cells by muscarinic acetylcholine receptors.

Molecular and cellular biochemistry 20121101

The tyrphostin AG1478 augments oridonin-induced A431 cell apoptosis by blockage of JNK MAPK and enhancement of oxidative stress.

Free radical research 20121101

Autocrine effect of EGFR ligands on the pro-inflammatory response induced by PM(2.5) exposure in human bronchial epithelial cells.

Archives of toxicology 20121001

Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts.

Arthritis and rheumatism 20121001

Cardiotoxin III suppresses MDA-MB-231 cell metastasis through the inhibition of EGF/EGFR-mediated signaling pathway.

Toxicon : official journal of the International Society on Toxinology 20121001

A novel epidermal growth factor-dependent extracellular signal-regulated MAP kinase cascade involved in sperm functionality in sheep.

Biology of reproduction 20121001

Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer.

Oncogene 20120913

Indoxyl sulfate enhances angiotensin II signaling through upregulation of epidermal growth factor receptor expression in vascular smooth muscle cells.

Life sciences 20120904

Effect of EGF-receptor tyrosine kinase inhibitor on Rab5 function during endocytosis.

Archives of biochemistry and biophysics 20120901

Regulated intramembrane cleavage of the EGF receptor.

Traffic (Copenhagen, Denmark) 20120801

The EGFR tyrosine kinase inhibitor tyrphostin AG-1478 causes hypomagnesemia and cardiac dysfunction.

Canadian journal of physiology and pharmacology 20120801

Simultaneous inhibition of EGFR and PI3K enhances radiosensitivity in human breast cancer.

International journal of radiation oncology, biology, physics 20120701

A novel role for epidermal growth factor receptor tyrosine kinase and its downstream endoplasmic reticulum stress in cardiac damage and microvascular dysfunction in type 1 diabetes mellitus.

Hypertension (Dallas, Tex. : 1979) 20120701

Increased activation of fibrocytes in patients with chronic obstructive asthma through an epidermal growth factor receptor-dependent pathway.

The Journal of allergy and clinical immunology 20120501

Neutrophil gelatinase-associated lipocalin (NGAL) expression is dependent on the tumor-associated sigma-2 receptor S2RPgrmc1.

The Journal of biological chemistry 20120427

Tyrosine kinase inhibitors influence ABCG2 expression in EGFR-positive MDCK BCRP cells via the PI3K/Akt signaling pathway.

ChemMedChem 20120401

Angiotensin AT1 receptor blockers suppress oxidized low-density lipoprotein-derived formation of foam cells.

European journal of pharmacology 20120315

Angiotensin-(1-7) inhibits epidermal growth factor receptor transactivation via a Mas receptor-dependent pathway.

British journal of pharmacology 20120301

Ovarian expression and regulation of the stromelysins during the periovulatory period in the human and the rat.

Biology of reproduction 20120301

ErbB4 localization to cardiac myocyte nuclei, and its role in myocyte DNA damage response.

Biochemical and biophysical research communications 20120203

Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells.

Phytotherapy research : PTR 20120101

Effect of bisphenol A on the EGFR-STAT3 pathway in MCF-7 breast cancer cells.

Molecular medicine reports 20120101

Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin.

Archives of virology 20120101

EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells.

Cellular signalling 20120101

An in vivo C. elegans model system for screening EGFR-inhibiting anti-cancer drugs.

PloS one 20120101

The EGF receptor and HER2 participate in TNF-α-dependent MAPK activation and IL-8 secretion in intestinal epithelial cells.

Mediators of inflammation 20120101

Specific protein kinase C isoforms α and βI are involved in follicle-stimulating hormone-induced mouse follicle-enclosed oocytes meiotic resumption.

PloS one 20120101

Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy.

Nature neuroscience 20111211

Cytosolic phospholipase A(2)α protects against Fas- but not LPS-induced liver injury.

Journal of hepatology 20111201

The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms.

Biochemical pharmacology 20111201

Insulin contributes to fine-tuning of the pancreatic beta-cell response to glucagon-like peptide-1.

Molecules and cells 20111031

Bile acids promote HCV replication through the EGFR/ERK pathway in replicon-harboring cells.

Intervirology 20111001

Mislocalization of large ARF-GEFs as a potential mechanism for BFA resistance in COG-deficient cells.

Experimental cell research 20111001

The balance between 4-hydroxynonenal and intrinsic glutathione/glutathione S-transferase A4 system may be critical for the epidermal growth factor receptor phosphorylation of human esophageal squamous cell carcinomas.

Molecular carcinogenesis 20111001

ADAM-17/tumor necrosis factor-α-converting enzyme inhibits neurogenesis and promotes gliogenesis from neural stem cells.

Stem cells (Dayton, Ohio) 20111001

Epigen is induced during the interleukin-13-stimulated cell proliferation in murine primary airway epithelial cells.

Experimental lung research 20111001

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis.

Nature medicine 20111001

ERK phosphorylation predicts synergism between gemcitabine and the epidermal growth factor receptor inhibitor AG1478.

Lung cancer (Amsterdam, Netherlands) 20110901

Epithelial growth factor receptor tyrosine kinase inhibitor prevents infiltration and cerebrospinal fluid dissemination in malignant glioma: an experimental study.

Neurosurgery 20110801

EGFR gene amplification is related to adverse clinical outcomes in cervical squamous cell carcinoma, making the EGFR pathway a novel therapeutic target.

British journal of cancer 20110726

Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: the role of size for intraocular drug delivery.

ACS nano 20110628

Small tyrosine kinase inhibitors interrupt EGFR signaling by interacting with erbB3 and erbB4 in glioblastoma cell lines.

Experimental cell research 20110610

Role of somatostatin receptor 1 and 5 on epidermal growth factor receptor mediated signaling.

Biochimica et biophysica acta 20110601

GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary.

Molecular endocrinology (Baltimore, Md.) 20110601

Activation of cumulus cell SMAD2/3 and epidermal growth factor receptor pathways are involved in porcine oocyte-cumulus cell expansion and steroidogenesis.

Molecular reproduction and development 20110601

Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism.

The Journal of clinical investigation 20110601

Expression and regulation of amphiregulin in Gsα-mutated human bone marrow stromal cells of fibrous dysplasia of mandible.

Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20110501

Endosomal signalling of epidermal growth factor receptors contributes to EGF-stimulated cell cycle progression in primary hepatocytes.

European journal of pharmacology 20110305

Epidermal growth factor receptor as a target for anti-proliferative treatment of proliferative cholangitis in hepatolithiasis.

The Journal of surgical research 20110301

Epidermal growth factor treatment switches δ-opioid receptor-stimulated extracellular signal-regulated kinases 1 and 2 signaling from an epidermal growth factor to an insulin-like growth factor-1 receptor-dependent mechanism.

Molecular pharmacology 20110201

Mechanisms of myogenic tone of coronary arteriole: Role of down stream signaling of the EGFR tyrosine kinase.

Microvascular research 20110101

EGF receptor exposed to oxidative stress acquires abnormal phosphorylation and aberrant activated conformation that impairs canonical dimerization.

PloS one 20110101

Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways.

BMC cancer 20110101

Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy.

PloS one 20110101

The prostaglandin E2 receptor, EP2, stimulates keratinocyte proliferation in mouse skin by G protein-dependent and {beta}-arrestin1-dependent signaling pathways.

The Journal of biological chemistry 20101217

Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides.

The Journal of biological chemistry 20101112

Increased Na, K-ATPase alpha2 isoform gene expression by ammonia in astrocytes and in brain in vivo.

Neurochemistry international 20101101

Serotonin increases ERK1/2 phosphorylation in astrocytes by stimulation of 5-HT2B and 5-HT2C receptors.

Neurochemistry international 20101101

Downregulated ABCG2 enhances sensitivity to topoisomerase I inhibitor in epidermal growth factor receptor tyrosine kinase inhibitor-resistant non-small cell lung cancer.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101101

α1-Adrenoceptor-mediated contraction of rat aorta is partly mediated via transactivation of the epidermal growth factor receptor.

British journal of pharmacology 20101101

Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells.

Experimental eye research 20100901

Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways.

Cancer letters 20100828

Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling.

Developmental biology 20100815

Modulation of the oncogene-dependent tissue factor expression by kinase suppressor of ras 1.

Thrombosis research 20100701

[Effects of EGFR inhibitor AG1478 in combination with celecoxib on the growth of gastric cancer cells].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100701

Epidermal growth factor receptor is a co-receptor for adeno-associated virus serotype 6.

Nature medicine 20100601

The antimicrobial peptide LL37 induces the migration of human pulp cells: a possible adjunct for regenerative endodontics.

Journal of endodontics 20100601

Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells.

Journal of neuro-oncology 20100501

New platform for controlled and sustained delivery of the EGF receptor tyrosine kinase inhibitor AG1478 using poly(lactic-co-glycolic acid) microspheres.

Journal of microencapsulation 20100501

Hypoxia-induced proliferation of human pulmonary microvascular endothelial cells depends on epidermal growth factor receptor tyrosine kinase activation.

American journal of physiology. Lung cellular and molecular physiology 20100401

Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells.

Biochemical pharmacology 20100301

Cell-type-specific roles of IGF-1R and EGFR in mediating Zn2+-induced ERK1/2 and PKB phosphorylation.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100301

The EGF receptor-sox2-EGF receptor feedback loop positively regulates the self-renewal of neural precursor cells.

Stem cells (Dayton, Ohio) 20100201

Effect of urotensin II on PC12 rat pheochromocytoma cells.

Journal of neuroendocrinology 20100201

[Effect of epidermal growth factor receptor on airway remodeling in asthmatic mice and its mechanism].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100201

Nanoscale imaging of epidermal growth factor receptor clustering: effects of inhibitors.

The Journal of biological chemistry 20100129

Differential contribution of direct-developing and stem cell-derived melanocytes to the zebrafish larval pigment pattern.

Developmental biology 20100115

Angiotensin II-induced migration of vascular smooth muscle cells is mediated by p38 mitogen-activated protein kinase-activated c-Src through spleen tyrosine kinase and epidermal growth factor receptor transactivation.

The Journal of pharmacology and experimental therapeutics 20100101

Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation.

The Journal of steroid biochemistry and molecular biology 20100101

JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells.

American journal of physiology. Gastrointestinal and liver physiology 20100101

Cross-talk between bradykinin and epidermal growth factor in regulating IL-6 production in human airway smooth muscle cells.

Chang Gung medical journal 20100101

EGFR signaling is differentially activated in patient-derived glioblastoma stem cells.

Journal of experimental therapeutics & oncology 20100101

Termination of tyrphostin AG1478 application results in different recovery of EGF receptor tyrosine residues 1045 and 1173 phosphorylation in A431 cells.

Cell biology international 20091216

Quercetin stimulates Na+/K+/2Cl- cotransport via PTK-dependent mechanisms in human airway epithelium.

American journal of respiratory cell and molecular biology 20091201

ERK phosphorylation in intact, adult brain by alpha(2)-adrenergic transactivation of EGF receptors.

Neurochemistry international 20091201

Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cells.

Canadian journal of physiology and pharmacology 20091201

Role of epidermal growth factor receptor in ovine fetal pulmonary vascular remodeling following exposure to high altitude long-term hypoxia.

High altitude medicine & biology 20091201

Evodiamine inhibits adipogenesis via the EGFR-PKCalpha-ERK signaling pathway.

FEBS letters 20091119

Suppression of ErbB-2 in androgen-independent human prostate cancer cells enhances cytotoxic effect by gemcitabine in an androgen-reduced environment.

Cancer letters 20091118

Role of epidermal growth factor receptor (EGFR) in corneal remodelling in diabetes.

Acta ophthalmologica 20091101

Naegleria fowleri induces MUC5AC and pro-inflammatory cytokines in human epithelial cells via ROS production and EGFR activation.

Microbiology (Reading, England) 20091101

Multipathway kinase signatures of multipotent stromal cells are predictive for osteogenic differentiation: tissue-specific stem cells.

Stem cells (Dayton, Ohio) 20091101

Off-target effects of epidermal growth factor receptor antagonists mediate retinal ganglion cell disinhibited axon growth.

Brain : a journal of neurology 20091101

Epidermal growth factor receptor inhibitors promote CNS axon growth through off-target effects on glia.

Neurobiology of disease 20091001

Effects of cigarette smoking on mucin production in human middle ear epithelial cells.

International journal of pediatric otorhinolaryngology 20091001

Desmoid cell motility is induced in vitro by rhEGF.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20090901

Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor.

Hepatology (Baltimore, Md.) 20090901

EGFR-PLCgamma1 signaling mediates high glucose-induced PKCbeta1-Akt activation and collagen I upregulation in mesangial cells.

American journal of physiology. Renal physiology 20090901

Regulation and function of tissue inhibitor of metalloproteinase (TIMP) 1 and TIMP3 in periovulatory rat granulosa cells.

Endocrinology 20090801

Dexamethasone enhances basal and TNF-alpha-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11beta-hydroxysteroid dehydrogenase 2 status in human proximal renal tubular cells.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601

A role for Gab1/SHP2 in thrombin activation of PAK1: gene transfer of kinase-dead PAK1 inhibits injury-induced restenosis.

Circulation research 20090508

Proliferative capacity of vein graft smooth muscle cells and fibroblasts in vitro correlates with graft stenosis.

Journal of vascular surgery 20090501

Cell migration in response to the amino-terminal fragment of urokinase requires epidermal growth factor receptor activation through an ADAM-mediated mechanism.

Journal of vascular surgery 20090501

Receptor tyrosine kinases as mediators of injury-induced bradykinin B1 receptor expression in rabbit aortic smooth muscle.

European journal of pharmacology 20090315

Epidermal growth factor receptor is involved in clusterin-induced astrocyte proliferation.

Neuroreport 20090304

Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478.

Biochemical pharmacology 20090301

Epidermal growth factor receptor lacking C-terminal autophosphorylation sites retains signal transduction and high sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor.

Cancer science 20090301

Genistein decreases androgen biosynthesis in rat Leydig cells by interference with luteinizing hormone-dependent signaling.

Toxicology letters 20090210

The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms.

Biochimica et biophysica acta 20090201

The epidermal growth factor tyrosine kinase inhibitor AG1478 and erlotinib reverse ABCG2-mediated drug resistance.

Oncology reports 20090201

Estradiol, progesterone, and transforming growth factor alpha regulate insulin-like growth factor binding protein-3 (IGFBP3) expression in mouse endometrial cells.

Zoological science 20090201

Tumor necrosis factor-alpha-stimulated membrane type 1-matrix metalloproteinase production is modulated by epidermal growth factor receptor signaling in human gingival fibroblasts.

Journal of periodontal research 20090201

TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype.

Breast cancer research and treatment 20090101

Arsenite suppresses Notch1 signaling in human keratinocytes.

The Journal of investigative dermatology 20090101

Therapeutic efficacy of 177Lu-CHX-A''-DTPA-hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy.

The Prostate 20090101

Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: novel chemotherapeutic targets in pancreatic endocrine tumors?

The American journal of gastroenterology 20090101

Global upregulation of gene expression associated with renal dysfunction in DOCA-salt-induced hypertensive rats occurs via signaling cascades involving epidermal growth factor receptor: a microarray analysis.

Vascular pharmacology 20090101

[Effects of theaflavins on the signal transduction pathway of epidermal growth factor receptor in airway mucous hypersecretion].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20090101

[Analysis of tyrphostin AG1478 effect on behavior of internalized EGF receptor at different stages of endocytosis].

Tsitologiia 20090101

Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.

Experimental & molecular medicine 20081231

Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation.

Psychopharmacology 20081201

Delta-opioid receptors activate ERK/MAP kinase via integrin-stimulated receptor tyrosine kinases.

Cellular signalling 20081201

Epidermal growth factor receptor (EGFR) regulates mechanical ventilation-induced lung injury in mice.

Translational research : the journal of laboratory and clinical medicine 20081201

c-Fos overexpression increases the proliferation of human hepatocytes by stabilizing nuclear Cyclin D1.

World journal of gastroenterology 20081107

The epidermal growth factor receptor mediates allergic airway remodelling in the rat.

The European respiratory journal 20081101

The transactivated epidermal growth factor receptor recruits Pyk2 to regulate Src kinase activity.

The Journal of biological chemistry 20081010

DNA vaccination controls Her-2+ tumors that are refractory to targeted therapies.

Cancer research 20080915

EGF mediates calcium-activated chloride channel activation in the human bronchial epithelial cell line 16HBE14o-: involvement of tyrosine kinase p60c-src.

American journal of physiology. Lung cellular and molecular physiology 20080901

Photodynamic targeting of EGFR does not predict the treatment outcome in combination with the EGFR tyrosine kinase inhibitor Tyrphostin AG1478.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080901

In human entrocytes, GLN transport and ASCT2 surface expression induced by short-term EGF are MAPK, PI3K, and Rho-dependent.

Digestive diseases and sciences 20080801

Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.

American journal of physiology. Cell physiology 20080801

Insulin-induced epidermal growth factor activation in vascular smooth muscle cells is ADAM-dependent.

Surgery 20080801

Stimulation by vasopressin of ERK phosphorylation and vector-driven water flux in astrocytes is transactivation-dependent.

European journal of pharmacology 20080610

Involvement of tyrosine kinase in the hyposmotic stimulation of I Ks in guinea-pig ventricular myocytes.

Pflugers Archiv : European journal of physiology 20080601

MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells.

American journal of physiology. Lung cellular and molecular physiology 20080601

Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: role of reactive oxygen species production and glutathione depletion.

Biochemical pharmacology 20080515

PI3-kinase and mitogen-activated protein kinase in cumulus cells mediate EGF-induced meiotic resumption of porcine oocyte.

Domestic animal endocrinology 20080501

Tumor necrosis factor-alpha enhances neutrophil adhesiveness: induction of vascular cell adhesion molecule-1 via activation of Akt and CaM kinase II and modifications of histone acetyltransferase and histone deacetylase 4 in human tracheal smooth muscle cells.

Molecular pharmacology 20080501

Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice.

Toxicology and applied pharmacology 20080501

Epidermal growth factor receptor activation by protein kinase C is necessary for FSH-induced meiotic resumption in porcine cumulus-oocyte complexes.

The Journal of endocrinology 20080501

Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells.

Microvascular research 20080501

Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells.

The Journal of biological chemistry 20080418

Lipopolysaccharide induces VCAM-1 expression and neutrophil adhesion to human tracheal smooth muscle cells: involvement of Src/EGFR/PI3-K/Akt pathway.

Toxicology and applied pharmacology 20080415

Epidermal growth factor receptor inhibitors enhance susceptibility to Fas-mediated apoptosis in oral squamous cell carcinoma cells.

Oral oncology 20080401

Luteinizing hormone signaling in preovulatory follicles involves early activation of the epidermal growth factor receptor pathway.

Molecular endocrinology (Baltimore, Md.) 20080401

Role of epidermal growth factor gene in the development of pancreatic cancer and efficiency of inhibitors of this gene in the treatment of pancreatic carcinoma.

Bulletin of experimental biology and medicine 20080401

Heparin-binding epidermal growth factor and Src family kinases in proliferation of renal epithelial cells.

American journal of physiology. Renal physiology 20080301

EGFR inhibitor enhances cisplatin sensitivity of oral squamous cell carcinoma cell lines.

Pathology oncology research : POR 20080301

Ebselen, a redox regulator containing a selenium atom, induces neurofilament M expression in cultured rat pheochromocytoma PC12 cells via activation of mitogen-activated protein kinase.

Journal of neuroscience research 20080215

Prostaglandin E2 upregulates EGF-stimulated signaling in mitogenic pathways involving Akt and ERK in hepatocytes.

Journal of cellular physiology 20080201

Thrombin increases hyposmotic taurine efflux and accelerates ICI-swell and RVD in 3T3 fibroblasts by a src-dependent EGFR transactivation.

Pflugers Archiv : European journal of physiology 20080201

Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase.

The Journal of biological chemistry 20080104

EGF-like peptides mediate FSH-induced maturation of cumulus cell-enclosed mouse oocytes.

Molecular reproduction and development 20080101

Angiotensin II activates extracellular signal-regulated kinase independently of receptor tyrosine kinases in renal smooth muscle cells: implications for blood pressure regulation.

The Journal of pharmacology and experimental therapeutics 20080101

Biochemical assay-based selectivity profiling of clinically relevant kinase inhibitors on mutant forms of EGF receptor.

Journal of receptor and signal transduction research 20080101

HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells.

PloS one 20080101

A role for SNX5 in the regulation of macropinocytosis.

BMC cell biology 20080101

Role of elevated EGFR phosphorylation in the induction of structural remodelling and altered mechanical properties of resistance artery from type 2 diabetic mice.

Diabetes/metabolism research and reviews 20080101

Leptin stimulates the proliferation of human oesophageal adenocarcinoma cells via HB-EGF and Tgfalpha mediated transactivation of the epidermal growth factor receptor.

British journal of biomedical science 20080101

EGFR plays a pivotal role in the regulation of polyamine-dependent apoptosis in intestinal epithelial cells.

Cellular signalling 20071201

Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.

European journal of pharmacology 20071114

Lysophosphatidylcholine stimulates EGF receptor activation and mesangial cell proliferation: regulatory role of Src and PKC.

Biochimica et biophysica acta 20071101

Involvement of KATP and KvLQT1 K+ channels in EGF-stimulated alveolar epithelial cell repair processes.

American journal of physiology. Lung cellular and molecular physiology 20071001

Heparin-binding EGF-like growth factor mediates oxyhemoglobin-induced suppression of voltage-dependent potassium channels in rabbit cerebral artery myocytes.

American journal of physiology. Heart and circulatory physiology 20070901

Epidermal growth factor receptor signaling modulates apoptosis via p38alpha MAPK-dependent activation of Bax in intestinal epithelial cells.

American journal of physiology. Gastrointestinal and liver physiology 20070901

Protease activated receptor 2 and epidermal growth factor receptor are involved in the regulation of human sperm motility.

Asian journal of andrology 20070901

Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism.

The Biochemical journal 20070715

Dynamic and differential regulation of NKCC1 by calcium and cAMP in the native human colonic epithelium.

The Journal of physiology 20070715

Epiregulin promotes proliferation and migration of renal proximal tubular cells.

American journal of physiology. Renal physiology 20070701

Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.

Endocrinology 20070701

Depolarization-induced, glutamate receptor-mediated, and transactivation-dependent extracellular-signal regulated kinase phosphorylation in cultured cerebellar granule neurons.

Neuroscience 20070629

Upregulation of retinoic acid receptor-beta by the epidermal growth factor-receptor inhibitor PD153035 is not mediated by blockade of ErbB pathways.

Journal of cellular physiology 20070601

The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity.

Neuron 20070524

Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potential.

Toxicology and applied pharmacology 20070515

ERK-dependent and -independent pathways trigger human neural progenitor cell migration.

Toxicology and applied pharmacology 20070515

Inhibition of ADAM17 reduces hypoxia-induced brain tumor cell invasiveness.

Cancer science 20070501

The control of tissue architecture over nuclear organization is crucial for epithelial cell fate.

Journal of cell science 20070501

Activation of mitogen-activated protein kinase by hepatocyte growth factor is stimulated by both alpha1- and beta2-adrenergic agonists in primary cultures of adult rat hepatocytes.

Journal of pharmacological sciences 20070401

Niflumic acid and AG-1478 reduce cigarette smoke-induced mucin synthesis: the role of hCLCA1.

Chest 20070401

Nicotine-induced vascular endothelial growth factor release via the EGFR-ERK pathway in rat vascular smooth muscle cells.

Life sciences 20070320

EGFR-activated signaling and actin remodeling regulate cyclic stretch-induced NRF2-ARE activation.

American journal of respiratory cell and molecular biology 20070301

Extracellular signal-regulated kinase activation by parathyroid hormone in distal tubule cells.

American journal of physiology. Renal physiology 20070301

The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806.

The Journal of biological chemistry 20070202

Signaling of mitochondrial biogenesis following oxidant injury.

The Journal of biological chemistry 20070126

Skeletal muscle stem cells express anti-apoptotic ErbB receptors during activation from quiescence.

Experimental cell research 20070115

Histone deacetylase inhibitors in combinations: will the preclinical promises be kept?

Cancer journal (Sudbury, Mass.) 20070101

Apoptosis induced by depsipeptide FK228 coincides with inhibition of survival signaling in lung cancer cells.

Cancer journal (Sudbury, Mass.) 20070101

Histamine stimulation of MMP-1(collagenase-1) secretion and gene expression in gastric epithelial cells: role of EGFR transactivation and the MAP kinase pathway.

The international journal of biochemistry & cell biology 20070101

Aldosterone rapidly activates protein kinase D via a mineralocorticoid receptor/EGFR trans-activation pathway in the M1 kidney CCD cell line.

The Journal of steroid biochemistry and molecular biology 20070101

Maximal beta3-adrenergic regulation of lipolysis involves Src and epidermal growth factor receptor-dependent ERK1/2 activation.

The Journal of biological chemistry 20061208

Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/gelatinase A.

Endocrine-related cancer 20061201

EGFRvIII undergoes activation-dependent downregulation mediated by the Cbl proteins.

Oncogene 20061019

GnRH actions on rat preovulatory follicles are mediated by paracrine EGF-like factors.

Molecular reproduction and development 20061001

Treatment of HNSCC cell lines with the EGFR-specific inhibitor cetuximab (Erbitux) results in paradox phosphorylation of tyrosine 1173 in the receptor.

FEBS letters 20060904

Gefitinib prevents bleomycin-induced lung fibrosis in mice.

American journal of respiratory and critical care medicine 20060901

Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells.

Toxicology letters 20060820

Role of epidermal growth factor receptor transactivation in alpha1B-adrenoceptor phosphorylation.

European journal of pharmacology 20060807

STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells.

Kidney international 20060801

Peroxisome proliferator-activated receptor-gamma inhibits cigarette smoke solution-induced mucin production in human airway epithelial (NCI-H292) cells.

American journal of physiology. Lung cellular and molecular physiology 20060701

Activation of the lutropin/choriogonadotropin receptor in MA-10 cells stimulates tyrosine kinase cascades that activate ras and the extracellular signal regulated kinases (ERK1/2).

Endocrinology 20060701

Leuprorelin acetate affects ERK1/2 activity in prostate cancer cells.

International journal of oncology 20060701

[Involvement of epidermal growth factor receptor signaling pathway in tamoxifen resistance of MCF-7 cells].

Ai zheng = Aizheng = Chinese journal of cancer 20060701

Activation of insulin-like growth factor type-1 receptor is required for H2O2-induced PKB phosphorylation in vascular smooth muscle cells.

Canadian journal of physiology and pharmacology 20060701

Metalloprotease-dependent amphiregulin release mediates tumor necrosis factor-alpha-induced IL-8 secretion in the human airway epithelial cell line NCI-H292.

Life sciences 20060522

Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase.

Biochemical pharmacology 20060514

Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.

The Journal of surgical research 20060501

Galphaq expression activates EGFR and induces Akt mediated cardiomyocyte survival: dissociation from Galphaq mediated hypertrophy.

Journal of molecular and cellular cardiology 20060501

Arachidonic acid induces ERK activation via Src SH2 domain association with the epidermal growth factor receptor.

Kidney international 20060501

Transcription levels of invasion-related genes in prostate cancer cells are modified by inhibitors of tyrosine kinase.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060501

HER2 expression as a potential marker for response to therapy targeted to the EGFR.

British journal of cancer 20060424

Vascular responses to alpha1-adrenergic receptors in small rat mesenteric arteries depend on mitochondrial reactive oxygen species.

Arteriosclerosis, thrombosis, and vascular biology 20060401

PAR-type thrombin receptors in renal carcinoma cells: PAR1-mediated EGFR activation promotes cell migration.

Oncology reports 20060401

Urokinase plasminogen activator receptor (uPAR) expression is reduced by tyrosine kinase inhibitors.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060401

Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation.

Biochemical and biophysical research communications 20060310

A novel mechanism for integrin-mediated ras activation in breast carcinoma cells: the alpha6beta4 integrin regulates ErbB2 translation and transactivates epidermal growth factor receptor/ErbB2 signaling.

Cancer research 20060301

Tyrosine kinase inhibitors alter adhesivity of prostatic cancer cells to extracellular matrix components.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060301

Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility.

Experimental cell research 20060215

Tyrphostin-A47 inhibitable tyrosine phosphorylation of flagellar proteins is associated with distinct alteration of motility pattern in hamster spermatozoa.

Molecular reproduction and development 20060201

Inhibition of autophosphorylation of epidermal growth factor receptor by small peptides in vitro.

British journal of pharmacology 20060201

Inhibition of epidermal growth factor receptor activation enhances in vivo histamine-stimulated gastric acid secretion in the rat.

Digestive diseases and sciences 20060201

Selective induction of cyclooxygenase-2 plays a role in lysophosphatidic acid regulated Fas ligand cell surface presentation.

FEBS letters 20060123

Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs.

Journal of cellular physiology 20060101

Blockade of EGFR and ErbB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis.

Cancer research 20060101

The invasive behaviour of prostatic cancer cells is suppressed by inhibitors of tyrosine kinase.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060101

Aldosterone stimulates activity and surface expression of NHE3 in human primary proximal tubule epithelial cells (RPTEC).

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101

Concomitant cell growth and differentiation are dependent on erbB1 and integrin activation in an autonomously surviving colon adenocarcinoma: involvement of autocrine amphiregulin secretion.

Anticancer research 20060101

[Oxidized glutathione induces activation of the epidermal growth factor receptor and MAP kinases ERK 1,2].

Tsitologiia 20060101

Toluene diisocyanate (TDI) induces production of inflammatory cytokines and chemokines by bronchial epithelial cells via the epidermal growth factor receptor and p38 mitogen-activated protein kinase pathways.

Experimental lung research 20060101

Signal transduction through substance P receptor in human glioblastoma cells: roles for Src and PKCdelta.

Cancer chemotherapy and pharmacology 20051201

Anilinodialkoxyquinazolines: screening epidermal growth factor receptor tyrosine kinase inhibitors for potential tumor imaging probes.

Journal of medicinal chemistry 20051117

PTPase inhibition restores ERK1/2 phosphorylation and protects mammary epithelial cells from apoptosis.

Biochemical and biophysical research communications 20051104

Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation.

Digestive diseases and sciences 20051101

Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells.

Cancer research 20051015

EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans.

Science (New York, N.Y.) 20051007

Cytokine-induced endothelial arginase expression is dependent on epidermal growth factor receptor.

American journal of respiratory cell and molecular biology 20051001

Air pollution particles activate NF-kappaB on contact with airway epithelial cell surfaces.

Toxicology and applied pharmacology 20051001

Enhanced efficacy of radioimmunotherapy with 90Y-CHX-A''-DTPA-hu3S193 by inhibition of epidermal growth factor receptor (EGFR) signaling with EGFR tyrosine kinase inhibitor AG1478.

Clinical cancer research : an official journal of the American Association for Cancer Research 20051001

beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts.

The Journal of biological chemistry 20050916

Correlation of translocation of tight junction protein Zonula occludens-1 and activation of epidermal growth factor receptor in the regulation of invasion of pancreatic cancer cells.

International journal of oncology 20050901

EGF-induced EGF-receptor and MAP kinase phosphorylation in goat cumulus cells during in vitro maturation.

Molecular reproduction and development 20050801

Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension.

Circulation 20050719

Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG 1478-mesylate, with albumin.

Analytical biochemistry 20050715

Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent.

Journal of cellular physiology 20050701

Epidermal growth factor receptor tyrosine kinase-mediated signalling contributes to diabetes-induced vascular dysfunction in the mesenteric bed.

British journal of pharmacology 20050701

A FRET-based probe for epidermal growth factor receptor bound non-covalently to a pair of synthetic amphipathic helixes.

Experimental cell research 20050701

Activation of the epidermal growth factor receptor in optic nerve astrocytes leads to early and transient induction of cyclooxygenase-2.

Investigative ophthalmology & visual science 20050601

Studies of tyrosine phosphorylation and Src family tyrosine kinases in the lens epithelium.

Investigative ophthalmology & visual science 20050601

PGE2 up-regulates vascular endothelial growth factor expression in MKN28 gastric cancer cells via epidermal growth factor receptor signaling system.

Experimental oncology 20050601

Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases.

Journal of neurochemistry 20050501

Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers.

Cancer research 20050501

Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors.

Breast cancer research and treatment 20050501

Profiling EGFR activity in head and neck squamous cell carcinoma by using a novel layered membrane Western blot technology.

Oral oncology 20050501

Inhibitors of tyrosine kinase inhibit the production of urokinase plasminogen activator in human prostatic cancer cells.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20050501

The role of tyrosine kinase-mediated pathways in diabetes-induced alterations in responsiveness of rat carotid artery.

Autonomic & autacoid pharmacology 20050401

Epidermal growth factor receptor-dependent and -independent pathways in hydrogen peroxide-induced mitogen-activated protein kinase activation in cardiomyocytes and heart fibroblasts.

The Journal of pharmacology and experimental therapeutics 20050301

Amphiregulin acts as an autocrine survival factor for adult sensory neurons.

Neuroreport 20050227

Growth of intestinal epithelium in organ culture is dependent on EGF signalling.

Experimental cell research 20050215

Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells.

Cancer research 20050215

Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor.

The Journal of biological chemistry 20050128

Novel use of zebrafish as a vertebrate model to screen radiation protectors and sensitizers.

International journal of radiation oncology, biology, physics 20050101

[Effect of tyrosine kinase inhibitors on airway remodeling in bronchial asthma].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20050101

Combining RNA interference and kinase inhibitors against cell signalling components involved in cancer.

BMC cancer 20050101

The effects of S-phase kinase-associated protein 2 (SKP2) on cell cycle status, viability, and chemoresistance in A549 lung adenocarcinoma cells.

Experimental lung research 20041201

Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.

Circulation research 20041112

Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells.

Endocrinology 20041101

Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I.

Molecular endocrinology (Baltimore, Md.) 20041101

Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells.

Journal of hepatology 20041101

Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor.

Journal of cardiovascular pharmacology 20041101

Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells.

Oncogene 20041014

Clustering of cellular prion protein induces ERK1/2 and stathmin phosphorylation in GT1-7 neuronal cells.

FEBS letters 20041008

Autocrine regulation of steroidogenic function of Leydig cells by transforming growth factor-alpha.

Molecular and cellular endocrinology 20040930

Activation of epidermal growth factor receptors directs astrocytes to organize in a network surrounding axons in the developing rat optic nerve.

Developmental biology 20040915

Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae.

Oncogene 20040909

The AG1478 tyrosine kinase inhibitor is an effective suppressor of leiomyoma cell growth.

Human reproduction (Oxford, England) 20040901

Mechanisms of vascular angiotensin II surface receptor regulation by epidermal growth factor.

Journal of cellular physiology 20040901

L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer.

American journal of physiology. Gastrointestinal and liver physiology 20040901

Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck.

Clinical cancer research : an official journal of the American Association for Cancer Research 20040901

Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cells.

Biochemical and biophysical research communications 20040723

Extracellular calcium-sensing receptor transactivates the epidermal growth factor receptor by a triple-membrane-spanning signaling mechanism.

Biochemical and biophysical research communications 20040723

The epidermal growth factor receptor (EGFR) and proline rich tyrosine kinase 2 (PYK2) are involved in tissue factor dependent factor VIIa signalling in HaCaT cells.

Thrombosis and haemostasis 20040701

Insulin reduces the requirement for EGFR transactivation in bombesin-induced DNA synthesis.

Biochemical and biophysical research communications 20040611

Epidermal growth factor differentially augments G(i)-mediated stimulation of c-Jun N-terminal kinase activity.

British journal of pharmacology 20040601

Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.

The Journal of biological chemistry 20040514

Sphingosine 1-phosphate transactivates the platelet-derived growth factor beta receptor and epidermal growth factor receptor in vascular smooth muscle cells.

Circulation research 20040430

gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension.

Circulation 20040413

Human airway trypsin-like protease increases mucin gene expression in airway epithelial cells.

American journal of respiratory cell and molecular biology 20040401

Combined inhibition of epidermal growth factor receptor and JAK/STAT pathways results in greater growth inhibition in vitro than single agent therapy.

Molecular cancer therapeutics 20040401

Inhibition of epidermal growth factor receptor signaling protects human malignant glioma cells from hypoxia-induced cell death.

Cancer research 20040301

Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses.

The Journal of biological chemistry 20040220

Selective inhibition of survival signal transduction pathways enhanced radiosensitivity in human esophageal cancer cell lines in vitro.

Anticancer research 20040101

Biglycan is internalized via a chlorpromazine-sensitive route.

Cellular & molecular biology letters 20040101

Angiotensin II regulation of TGF-beta in murine mesangial cells involves both PI3 kinase and MAP kinase.

Annals of clinical and laboratory science 20040101

Epidermal growth factor induction of phenotype-dependent cell cycle arrest in vascular smooth muscle cells is through the mitogen-activated protein kinase pathway.

The Journal of biological chemistry 20031226

Antagonism of rat beta-cell voltage-dependent K+ currents by exendin 4 requires dual activation of the cAMP/protein kinase A and phosphatidylinositol 3-kinase signaling pathways.

The Journal of biological chemistry 20031226

Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinase-dependent pathways.

Cellular signalling 20031201

Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells.

Cancer research 20031015

Leukotrienes mediate part of Ova-induced lung effects in mice via EGFR.

American journal of physiology. Lung cellular and molecular physiology 20031001

Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor.

Experimental cell research 20031001

Expression of ErbB receptors in ES cell-derived cardiomyocytes.

Biochemical and biophysical research communications 20030912

EGF receptor mediates adhesion-dependent activation of the Rac GTPase: a role for phosphatidylinositol 3-kinase and Vav2.

Oncogene 20030904

Activation of ERK1/2 by platelet-activating factor receptor is independent of receptor internalisation and G-protein activation.

Cellular signalling 20030901

Epidermal growth factor receptor regulates normal urothelial regeneration.

Laboratory investigation; a journal of technical methods and pathology 20030901

Activated epidermal growth factor receptor (ErbB1) protects the heart against stress-induced injury in mice.

American journal of physiology. Regulatory, integrative and comparative physiology 20030801

Transactivation of the epidermal growth factor receptor mediates parathyroid hormone and prostaglandin F2 alpha-stimulated mitogen-activated protein kinase activation in cultured transgenic murine osteoblasts.

Molecular endocrinology (Baltimore, Md.) 20030801

Alpha-adrenergic stimulation of ERK phosphorylation in astrocytes is alpha(2)-specific and may be mediated by transactivation.

Brain research 20030718

Inhibition of zebrafish epidermal growth factor receptor activity results in cardiovascular defects.

Mechanisms of development 20030701

Activation of mitogen-activated protein kinase by cholinergic agonists and EGF in human compared with rat cultured conjunctival goblet cells.

Investigative ophthalmology & visual science 20030601

Inhibitors that target protein kinases for the treatment of ovarian carcinoma.

American journal of obstetrics and gynecology 20030501

Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR).

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401

Dissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells.

Journal of cellular physiology 20030301

Signal transduction pathways used by EGF to stimulate protein secretion in rat lacrimal gland.

Investigative ophthalmology & visual science 20030301

P2Y receptor-mediated stimulation of Müller glial cell DNA synthesis: dependence on EGF and PDGF receptor transactivation.

Investigative ophthalmology & visual science 20030301

Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201

Relationship of EGFR signal-transduction modulation by tyrosine kinase inhibitors to chemosensitivity and programmed cell death in lung cancer cell lines.

Methods in molecular medicine 20030101

Phosphorylation and subcellular distribution of connexin43 in normal and stressed cells.

Cell and tissue research 20030101

[Effect of EGF on the intracellular distribution of heat-shock proteins in A431 cells].

Tsitologiia 20030101

Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor.

The Journal of biological chemistry 20021220

Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors. Epidermal growth factor.

Science's STKE : signal transduction knowledge environment 20021203

ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases.

American journal of physiology. Heart and circulatory physiology 20021201

Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.

American journal of respiratory cell and molecular biology 20021201

Lyn- and ERK-mediated vs. Ca2+ -mediated neutrophil O responses with thermal injury.

American journal of physiology. Cell physiology 20021101

Activation of extracellular-regulated kinase by 5-hydroxytryptamine(2A) receptors in PC12 cells is protein kinase C-independent and requires calmodulin and tyrosine kinases.

The Journal of pharmacology and experimental therapeutics 20021101

Angiotensin II triggers EGFR tyrosine kinase-dependent Ca2+ influx in afferent arterioles.

Hypertension (Dallas, Tex. : 1979) 20021101

Activation of mitogen-activated protein kinase pathway by the antiandrogen hydroxyflutamide in androgen receptor-negative prostate cancer cells.

Cancer research 20021101

Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation.

Cancer research 20021101

4-Hydroxy-2-nonenal enhances fibronectin production by IMR-90 human lung fibroblasts partly via activation of epidermal growth factor receptor-linked extracellular signal-regulated kinase p44/42 pathway.

Toxicology and applied pharmacology 20021101

Secretin regulates paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.

American journal of physiology. Gastrointestinal and liver physiology 20021001

Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion.

American journal of physiology. Gastrointestinal and liver physiology 20021001

Tyrosine kinases regulate intracellular calcium during alpha(2)-adrenergic contraction in rat aorta.

American journal of physiology. Heart and circulatory physiology 20021001

Antagonistic and agonistic effects of quinazoline tyrosine kinase inhibitors on mutant EGF receptor function.

International journal of cancer 20020910

Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases.

The Journal of biological chemistry 20020830

Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion.

Cancer research 20020615

Direct inhibition of the cloned Kv1.5 channel by AG-1478, a tyrosine kinase inhibitor.

American journal of physiology. Cell physiology 20020601

Inhibitory effect and its kinetic analysis of tyrphostin AG1478 on recombinant human protein kinase CK2 holoenzyme.

Acta pharmacologica Sinica 20020601

Vitamin D inhibits the activation of stress-activated protein kinases by physiological and environmental stresses in keratinocytes.

The Journal of endocrinology 20020601

EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma.

Cancer cell 20020601

alpha 2B-adrenergic receptor activates MAPK via a pathway involving arachidonic acid metabolism, matrix metalloproteinases, and epidermal growth factor receptor transactivation.

The Journal of biological chemistry 20020531

Role of calmodulin in the modulation of the MAPK signalling pathway and the transactivation of epidermal growth factor receptor mediated by PKC.

FEBS letters 20020424

Independence of angiotensin II-induced MAP kinase activation from angiotensin type 1 receptor internalization in clone 9 hepatocytes.

Molecular endocrinology (Baltimore, Md.) 20020301

Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy.

Nature medicine 20020301

Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.

The Journal of biological chemistry 20020222

Regulation of sarcolemmal Na(+)/H(+) exchange by hydrogen peroxide in adult rat ventricular myocytes.

Cardiovascular research 20020201

TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor.

Biochemical and biophysical research communications 20020111

CD95-mediated apoptosis of human glioma cells: modulation by epidermal growth factor receptor activity.

Brain pathology (Zurich, Switzerland) 20020101

Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling.

Cancer research 20020101

Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20011215

Transactivation of the epidermal growth factor receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction.

The Journal of biological chemistry 20011214

Induction of EGFR-dependent and EGFR-independent signaling pathways by ultraviolet A irradiation.

DNA and cell biology 20011201

Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.

Journal of the American College of Cardiology 20011101

EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin.

American journal of physiology. Cell physiology 20010901

Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor.

Journal of neurosurgery 20010901

Activation of the EGF receptor signaling pathway in airway epithelial cells exposed to Utah Valley PM.

American journal of physiology. Lung cellular and molecular physiology 20010801

Further evidence for the involvement of insulin receptor substrates in epidermal growth factor-induced activation of phosphatidylinositol 3-kinase.

European journal of biochemistry 20010801

Extremely low-dose ionizing radiation causes activation of mitogen-activated protein kinase pathway and enhances proliferation of normal human diploid cells.

Cancer research 20010715

Gi-mediated activation of the Syk kinase by the receptor mimetic basic secretagogues of mast cells: role in mediating arachidonic acid/metabolites release.

Journal of immunology (Baltimore, Md. : 1950) 20010701

Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse.

Nature 20010517

c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.

The Journal of biological chemistry 20010511

Prevention of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the MCF-10A cell line: correlation with increased transforming growth factor alpha production.

Cancer research 20010415

High-performance liquid chromatographic analysis of the tyrphostin AG1478, a specific inhibitor of the epidermal growth factor receptor tyrosine kinase, in mouse plasma.

Journal of chromatography. B, Biomedical sciences and applications 20010415

Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions.

British journal of cancer 20010401

Thrombin-induced p38 mitogen-activated protein kinase activation is mediated by epidermal growth factor receptor transactivation pathway.

British journal of pharmacology 20010401

The relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells.

Oncogene 20010315

Transmodulation of epidermal growth factor receptor mediates IL-1 beta-induced MMP-1 expression in cultured human keratinocytes.

International journal of molecular medicine 20010301

BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells.

Biochemical and biophysical research communications 20010216

STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma.

Blood 20010215

Activation of extracellular-regulated kinases by normal and mutant EGF receptors.

Biochimica et biophysica acta 20010205

N-acetylcysteine inhibits angiotensin ii-mediated activation of extracellular signal-regulated kinase and epidermal growth factor receptor.

Biochemical and biophysical research communications 20010202

Tyrosine kinase involvement in renal arteriolar constrictor responses to angiotensin II.

Hypertension (Dallas, Tex. : 1979) 20010201

Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation.

Circulation research 20010119

Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications.

Cancer letters 20010101

Signal therapy for RAS-induced cancers in combination of AG 879 and PP1, specific inhibitors for ErbB2 and Src family kinases, that block PAK activation.

Cancer journal (Sudbury, Mass.) 20010101