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GYKI53655 HCl

CAS No.:
143692-48-2
Catalog Number:
AG00AKQS
Molecular Formula:
C19H21ClN4O3
Molecular Weight:
388.8480
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$223
- +
10mg
99%
1 week
United States
$293
- +
50mg
99%
1 week
United States
$1015
- +
100mg
99%
1 week
United States
$1723
- +
Product Description
Catalog Number:
AG00AKQS
Chemical Name:
GYKI53655 HCl
CAS Number:
143692-48-2
Molecular Formula:
C19H21ClN4O3
Molecular Weight:
388.8480
MDL Number:
MFCD01941362
IUPAC Name:
5-(4-aminophenyl)-N,8-dimethyl-8,9-dihydro-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-7-carboxamide;hydrochloride
InChI:
InChI=1S/C19H20N4O3.ClH/c1-11-7-13-8-16-17(26-10-25-16)9-15(13)18(22-23(11)19(24)21-2)12-3-5-14(20)6-4-12;/h3-6,8-9,11H,7,10,20H2,1-2H3,(H,21,24);1H
InChI Key:
ASLCSBBDVWPSQT-UHFFFAOYSA-N
SMILES:
CNC(=O)N1N=C(c2ccc(cc2)N)c2c(CC1C)cc1c(c2)OCO1.Cl
Properties
Complexity:
561  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
388.13g/mol
Formal Charge:
0
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
388.852g/mol
Monoisotopic Mass:
388.13g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
89.2A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
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Simultaneous contribution of two rod pathways to AII amacrine and cone bipolar cell light responses. Journal of neurophysiology 20050301
Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience 20041110
Characterisation of the effects of ATPA, a GLU(K5) kainate receptor agonist, on GABAergic synaptic transmission in the CA1 region of rat hippocampal slices. Neuropharmacology 20040901
Distinct properties of carbachol- and DHPG-induced network oscillations in hippocampal slices. Neuropharmacology 20040901
Functional properties of spontaneous EPSCs and non-NMDA receptors in rod amacrine (AII) cells in the rat retina. The Journal of physiology 20030615
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The selective iGluR1-4 (AMPA) antagonist LY300168 attenuates morphine-withdrawal-induced activation of locus coeruleus neurons and behavioural signs of morphine withdrawal. Neuropharmacology 20030101
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Functional characteristics of non-NMDA-type ionotropic glutamate receptor channels in AII amacrine cells in rat retina. The Journal of physiology 20020701
Ca(2+) influx through AMPA or kainate receptors alone is sufficient to initiate excitotoxicity in cultured oligodendrocytes. Neurobiology of disease 20020301
AMPA-induced Ca(2+) influx in cultured rat cortical nonpyramidal neurones: pharmacological characterization using fura-2 microfluorimetry. European journal of pharmacology 20020301
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AMPA receptor properties at the synapse between retinal afferents and thalamocortical cells in the dorsal lateral geniculate nucleus of the rat. Neuroscience letters 20011201
A critical role of a facilitatory presynaptic kainate receptor in mossy fiber LTP. Neuron 20011120
Positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA) receptors in prefrontal cortical pyramidal neurons by a novel allosteric potentiator. The Journal of pharmacology and experimental therapeutics 20010701
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Properties