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Home Other Building Blocks (N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE

(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE

CAS No.:
169505-93-5
Catalog Number:
AG00AKQ9
Molecular Formula:
C24H30Cl2N2O2
Molecular Weight:
449.4132
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$154
- +
10mg
99%
1 week
United States
$223
- +
50mg
99%
1 week
United States
$682
- +
100mg
99%
1 week
United States
$1098
- +
Product Description
Catalog Number:
AG00AKQ9
Chemical Name:
(N-[2-(2-CYCLOPROPYLMETHOXYPHENOXY)ETHYL]-5-CHLORO-ALPHA,ALPHA-DIMETHYL-1H-INDOLE-3-ETHANAMINE) HYDROCHLORIDE
CAS Number:
169505-93-5
Molecular Formula:
C24H30Cl2N2O2
Molecular Weight:
449.4132
MDL Number:
MFCD09971032
IUPAC Name:
1-(5-chloro-1H-indol-3-yl)-N-[2-[2-(cyclopropylmethoxy)phenoxy]ethyl]-2-methylpropan-2-amine;hydrochloride
InChI:
InChI=1S/C24H29ClN2O2.ClH/c1-24(2,14-18-15-26-21-10-9-19(25)13-20(18)21)27-11-12-28-22-5-3-4-6-23(22)29-16-17-7-8-17;/h3-6,9-10,13,15,17,26-27H,7-8,11-12,14,16H2,1-2H3;1H
InChI Key:
QFOPFGRPNPCPBX-UHFFFAOYSA-N
SMILES:
Clc1ccc2c(c1)c(c[nH]2)CC(NCCOc1ccccc1OCC1CC1)(C)C.Cl
Properties
Complexity:
513  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
448.168g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
449.416g/mol
Monoisotopic Mass:
448.168g/mol
Rotatable Bond Count:
10  
Topological Polar Surface Area:
46.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Identification of alpha 1L-adrenoceptor in mice and its abolition by alpha 1A-adrenoceptor gene knockout. British journal of pharmacology 20081201
Noradrenergic vasoconstriction of pig prostatic small arteries. Naunyn-Schmiedeberg's archives of pharmacology 20080201
Alpha(1A/L)-adrenoceptors mediate contraction of the circular smooth muscle of the pig urethra. Autonomic & autacoid pharmacology 20061001
Selective agonists reveal alpha(1A)- and alpha(1B)-adrenoceptor subtypes in caudal artery of the young rat. Autonomic & autacoid pharmacology 20061001
Alpha1L-adrenoceptors mediate contractions of the isolated mouse prostate. European journal of pharmacology 20060701
Different roles of alpha1-adrenoceptor subtypes in mediating cardiomyocyte protein synthesis in neonatal rats. Clinical and experimental pharmacology & physiology 20040901
alpha1A-adrenergic receptor mediated pressor response to phenylephrine in anesthetized rat. Science in China. Series C, Life sciences 20040201
Functional alpha1-adrenergic receptor subtypes in human right gastroepiploic artery. Acta pharmacologica Sinica 20030401
RS-17053 (N-[2-(2-cyclopropylmethoxyphenoxy)ethyl]-5-chloro-alpha, alpha-dimethyl-1H-indole-3-ethanamine hydrochloride), a selective alpha 1A-adrenoceptor antagonist, displays low affinity for functional alpha 1-adrenoceptors in human prostate: implications for adrenoceptor classification. Molecular pharmacology 19960201
Properties